Gene Symbol | TRIT1 |
Entrez Gene ID | 54802 |
Full Name | tRNA isopentenyltransferase 1 |
Synonyms | GRO1,IPPT,IPT,IPTase,MOD5,hGRO1 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a protein that that is targeted to the mitochondrion and modifies transfer RNAs (tRNAs) by adding a dimethylallyl group onto the adenine at position 37. This modification is important for maintaining the correct reading frame during protein translation. This gene is considered a tumor suppressor and its expression can decrease cell growth. Alternative splicing results in multiple transcripts variants, most of which are likely non-functional. [provided by RefSeq, Aug 2015]. |
Disorder MIM: |