IL17RD cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	IL17RD
Entrez Gene ID	54756
Full Name	interleukin 17 receptor D
Synonyms	HH18,IL-17RD,IL17RLM,SEF
General protein information	Preferred Names interleukin 17 receptor D Names interleukin-17 receptor D IL-17 receptor D IL17Rhom interleukin-17 receptor-like protein sef homolog
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 3 Map Location: 3p14.3
Summary	This gene encodes a membrane protein belonging to the interleukin-17 receptor (IL-17R) protein family. The encoded protein is a component of the interleukin-17 receptor signaling complex, and the interaction between this protein and IL-17R does not require the interleukin. The gene product also affects fibroblast growth factor signaling, inhibiting or stimulating growth through MAPK/ERK signaling. Alternate splicing generates multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2016].
Disorder MIM:	606807
Disorder Html:	Hypogonadotropic hypogonadism 18 with or without anosmia, 615267 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_017563.5	NP_060033.3	interleukin-17 receptor D isoform a precursor
XM_011533849.2	XP_011532151.2	interleukin-17 receptor D isoform X1
XM_005265238.4	XP_005265295.1	interleukin-17 receptor D isoform X2
NM_017563.4	NP_060033.3	interleukin-17 receptor D isoform a precursor
XM_006713209.3	XP_006713272.1	interleukin-17 receptor D isoform X1
NM_001318864.1	NP_001305793.1	interleukin-17 receptor D isoform b

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	IL17RD	XP_541835.3
Bos taurus (cattle)	IL17RD	NP_001192356.1
Rattus norvegicus (Norway rat)	Il17rd	NP_001178866.1
Mus musculus (house mouse)	Il17rd	NP_602319.1
Danio rerio (zebrafish)	il17rd	NP_705946.1
Homo sapiens (human)	IL17RD	NP_060033.3
	IL17RD	XP_001100582.1
Gallus gallus (chicken)	IL17RD	NP_989846.1
Xenopus tropicalis (tropical clawed frog)	il17rd	XP_002940076.1
Pan troglodytes (chimpanzee)	IL17RD	XP_516549.3

Gene Ontology
Bibliography

Related articles in PubMed

miR-193a-3p is a Key Tumor Suppressor in Ulcerative Colitis-Associated Colon Cancer and Promotes Carcinogenesis through Upregulation of IL17RD.
Pekow J, Meckel K, Dougherty U, Huang Y, Chen X, Almoghrabi A, Mustafi R, Ayaloglu-Butun F, Deng Z, Haider HI, Hart J, Rubin DT, Kwon JH, Bissonnette M
Clinical cancer research : an official journal of the American Association for Cancer Research23(17)5281-5291(2017 Sep)

Loss of hSef promotes metastasis through upregulation of EMT in prostate cancer.
Hori S, Wadhwa K, Pisupati V, Zecchini V, Ramos-Montoya A, Warren AY, Neal DE, Gnanapragasam VJ
International journal of cancer140(8)1881-1887(2017 04)

Sef Regulates Epithelial-Mesenchymal Transition in Breast Cancer Cells.
He Q, Gong Y, Gower L, Yang X, Friesel RE
Journal of cellular biochemistry117(10)2346-56(2016 Oct)

Orphan receptor IL-17RD regulates Toll-like receptor signalling via SEFIR/TIR interactions.
Mellett M, Atzei P, Bergin R, Horgan A, Floss T, Wurst W, Callanan JJ, Moynagh PN
Nature communications66669(2015 Mar)

Expression and regulation of the tumor suppressor, SEF, during folliculogenesis in humans and mice.
Lutwak E, Price CA, Abramovich SS, Rabinovitz S, Granot I, Dekel N, Ron D
Reproduction (Cambridge, England)148(5)507-17(2014 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Taken together, these data suggest evidence that loss of hSef may be a critical event facilitating tumor dissemination of prostate cancer through alteration of EMT.
Title: Loss of hSef promotes metastasis through upregulation of EMT in prostate cancer.

Low SEF expression is associated with Epithelial-Mesenchymal Transition in Breast Cancer and thus Metastasis in breast Cancer.
Title: Sef Regulates Epithelial-Mesenchymal Transition in Breast Cancer Cells.

IL17RD negatively regulates Toll-like receptor (TLR)-induced responses.
Title: Orphan receptor IL-17RD regulates Toll-like receptor signalling via SEFIR/TIR interactions.

Demonstrate SEF expression in a healthy ovary during folliculogenesis and suggest hormonal regulation of its expression may be an important factor involved in intra-ovarian control mechanisms.
Title: Expression and regulation of the tumor suppressor, SEF, during folliculogenesis in humans and mice.

Downregulation of Dusp6, Sprouty4, and Sef--negative modulators of FGF2/ERK1/2 signaling--was present in eutopic endometria of adenomyosis, which may play critical roles in the development of adenomyosis.
Title: Loss of expressions of Dusp6, Sprouty4, and Sef, negative regulators of FGF2/ERK1/2 signaling, in the endometrium of women with adenomyosis.

The following IL17RD gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IL17RD cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu37307	NM_001318864.1 Latest version!	Homo sapiens interleukin 17 receptor D (IL17RD), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu37307	XM_011533849.2 Latest version!	Homo sapiens interleukin 17 receptor D (IL17RD), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu37307	XM_006713209.3 Latest version!	Homo sapiens interleukin 17 receptor D (IL17RD), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu09609	NM_017563.5 Latest version!	Homo sapiens interleukin 17 receptor D (IL17RD), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$517.30 $739.00
OHu37306	XM_005265238.4 Latest version!	Homo sapiens interleukin 17 receptor D (IL17RD), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
View Old Accession Versions >>
OHu09609	NM_017563.4	Homo sapiens interleukin 17 receptor D (IL17RD), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$517.30 $739.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IL17RD ( NM_001318864.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001305793.1 Homo sapiens interleukin 17 receptor D (IL17RD), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu37307
Clone ID Related Accession (Same CDS sequence)	XM_011533849.2 , XM_006713209.3 , NM_001318864.1
Accession Version	NM_001318864.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1788bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-05
Organism	Homo sapiens(human)
Product	interleukin-17 receptor D isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY005493.1, AF494211.1, AC097358.2 and BQ017683.1. On Jan 15, 2016 this sequence version replaced XM_011533850.1. Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream start site, compared to variant 2. It encodes a shorter isoform (b) which has a shorter N-terminus, compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC038369.1, AF494211.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1966682, SAMEA1968189 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAATCTC AACCTTTCCT GAATATGAAA TTTGAAACGG ATTATTTCGT AAAGGTTGTC 
CCTTTTCCTT CCATTAAAAA CGAAAGCAAT TACCACCCTT TCTTCTTTAG AACCCGAGCC 
TGTGACCTGT TGTTACAGCC GGACAATCTA GCTTGTAAAC CCTTCTGGAA GCCTCGGAAC 
CTGAACATCA GCCAGCATGG CTCGGACATG CAGGTGTCCT TCGACCATGC ACCGCACAAC 
TTCGGCTTCC GTTTCTTCTA TCTTCACTAC AAGCTCAAGC ACGAAGGACC TTTCAAGCGA 
AAGACCTGTA AGCAGGAGCA AACTACAGAG ACGACCAGCT GCCTCCTTCA AAATGTTTCT 
CCAGGGGATT ATATAATTGA GCTGGTGGAT GACACTAACA CAACAAGAAA AGTGATGCAT 
TATGCCTTAA AGCCAGTGCA CTCCCCGTGG GCCGGGCCCA TCAGAGCCGT GGCCATCACA 
GTGCCACTGG TAGTCATATC GGCATTCGCG ACGCTCTTCA CTGTGATGTG CCGCAAGAAG 
CAACAAGAAA ATATATATTC ACATTTAGAT GAAGAGAGCT CTGAGTCTTC CACATACACT 
GCAGCACTCC CAAGAGAGAG GCTCCGGCCG CGGCCGAAGG TCTTTCTCTG CTATTCCAGT 
AAAGATGGCC AGAATCACAT GAATGTCGTC CAGTGTTTCG CCTACTTCCT CCAGGACTTC 
TGTGGCTGTG AGGTGGCTCT GGACCTGTGG GAAGACTTCA GCCTCTGTAG AGAAGGGCAG 
AGAGAATGGG TCATCCAGAA GATCCACGAG TCCCAGTTCA TCATTGTGGT TTGTTCCAAA 
GGTATGAAGT ACTTTGTGGA CAAGAAGAAC TACAAACACA AAGGAGGTGG CCGAGGCTCG 
GGGAAAGGAG AGCTCTTCCT GGTGGCGGTG TCAGCCATTG CCGAAAAGCT CCGCCAGGCC 
AAGCAGAGTT CGTCCGCGGC GCTCAGCAAG TTTATCGCCG TCTACTTTGA TTATTCCTGC 
GAGGGAGACG TCCCCGGTAT CCTAGACCTG AGTACCAAGT ACAGACTCAT GGACAATCTT 
CCTCAGCTCT GTTCCCACTT GCACTCCCGA GACCACGGCC TCCAGGAGCC GGGGCAGCAC 
ACGCGACAGG GCAGCAGAAG GAACTACTTC CGGAGCAAGT CAGGCCGGTC CCTATACGTC 
GCCATTTGCA ACATGCACCA GTTTATTGAC GAGGAGCCCG ACTGGTTCGA AAAGCAGTTC 
GTTCCCTTCC ATCCTCCTCC ACTGCGCTAC CGGGAGCCAG TCTTGGAGAA ATTTGATTCG 
GGCTTGGTTT TAAATGATGT CATGTGCAAA CCAGGGCCTG AGAGTGACTT CTGCCTAAAG 
GTAGAGGCGG CTGTTCTTGG GGCAACCGGA CCAGCCGACT CCCAGCACGA GAGTCAGCAT 
GGGGGCCTGG ACCAAGACGG GGAGGCCCGG CCTGCCCTTG ACGGTAGCGC CGCCCTGCAA 
CCCCTGCTGC ACACGGTGAA AGCCGGCAGC CCCTCGGACA TGCCGCGGGA CTCAGGCATC 
TATGACTCGT CTGTGCCCTC ATCCGAGCTG TCTCTGCCAC TGATGGAAGG ACTCTCGACG 
GACCAGACAG AAACGTCTTC CCTGACGGAG AGCGTGTCCT CCTCTTCAGG CCTGGGTGAG 
GAGGAACCTC CTGCCCTTCC TTCCAAGCTC CTCTCTTCTG GGTCATGCAA AGCAGATCTT 
GGTTGCCGCA GCTACACTGA TGAACTCCAC GCGGTCGCCC CTTTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001305793.1
CDS	555..2342
Translation	MESQPFLNMKFETDYFVKVVPFPSIKNESNYHPFFFRTRACDLLLQPDNLACKPFWKPRNLNISQHGSDMQVSFDHAPHNFGFRFFYLHYKLKHEGPFKRKTCKQEQTTETTSCLLQNVSPGDYIIELVDDTNTTRKVMHYALKPVHSPWAGPIRAVAITVPLVVISAFATLFTVMCRKKQQENIYSHLDEESSESSTYTAALPRERLRPRPKVFLCYSSKDGQNHMNVVQCFAYFLQDFCGCEVALDLWEDFSLCREGQREWVIQKIHESQFIIVVCSKGMKYFVDKKNYKHKGGGRGSGKGELFLVAVSAIAEKLRQAKQSSSAALSKFIAVYFDYSCEGDVPGILDLSTKYRLMDNLPQLCSHLHSRDHGLQEPGQHTRQGSRRNYFRSKSGRSLYVAICNMHQFIDEEPDWFEKQFVPFHPPPLRYREPVLEKFDSGLVLNDVMCKPGPESDFCLKVEAAVLGATGPADSQHESQHGGLDQDGEARPALDGSAALQPLLHTVKAGSPSDMPRDSGIYDSSVPSSELSLPLMEGLSTDQTETSSLTESVSSSSGLGEEEPPALPSKLLSSGSCKADLGCRSYTDELHAVAPL

Target ORF information:

RefSeq Version	NM_001318864.1
Organism	Homo sapiens(human)
Definition	Homo sapiens interleukin 17 receptor D (IL17RD), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001318864.1

ORF Insert Sequence:

ATGGAATCTC AACCTTTCCT GAATATGAAA TTTGAAACGG ATTATTTCGT AAAGGTTGTC 
CCTTTTCCTT CCATTAAAAA CGAAAGCAAT TACCACCCTT TCTTCTTTAG AACCCGAGCC 
TGTGACCTGT TGTTACAGCC GGACAATCTA GCTTGTAAAC CCTTCTGGAA GCCTCGGAAC 
CTGAACATCA GCCAGCATGG CTCGGACATG CAGGTGTCCT TCGACCATGC ACCGCACAAC 
TTCGGCTTCC GTTTCTTCTA TCTTCACTAC AAGCTCAAGC ACGAAGGACC TTTCAAGCGA 
AAGACCTGTA AGCAGGAGCA AACTACAGAG ACGACCAGCT GCCTCCTTCA AAATGTTTCT 
CCAGGGGATT ATATAATTGA GCTGGTGGAT GACACTAACA CAACAAGAAA AGTGATGCAT 
TATGCCTTAA AGCCAGTGCA CTCCCCGTGG GCCGGGCCCA TCAGAGCCGT GGCCATCACA 
GTGCCACTGG TAGTCATATC GGCATTCGCG ACGCTCTTCA CTGTGATGTG CCGCAAGAAG 
CAACAAGAAA ATATATATTC ACATTTAGAT GAAGAGAGCT CTGAGTCTTC CACATACACT 
GCAGCACTCC CAAGAGAGAG GCTCCGGCCG CGGCCGAAGG TCTTTCTCTG CTATTCCAGT 
AAAGATGGCC AGAATCACAT GAATGTCGTC CAGTGTTTCG CCTACTTCCT CCAGGACTTC 
TGTGGCTGTG AGGTGGCTCT GGACCTGTGG GAAGACTTCA GCCTCTGTAG AGAAGGGCAG 
AGAGAATGGG TCATCCAGAA GATCCACGAG TCCCAGTTCA TCATTGTGGT TTGTTCCAAA 
GGTATGAAGT ACTTTGTGGA CAAGAAGAAC TACAAACACA AAGGAGGTGG CCGAGGCTCG 
GGGAAAGGAG AGCTCTTCCT GGTGGCGGTG TCAGCCATTG CCGAAAAGCT CCGCCAGGCC 
AAGCAGAGTT CGTCCGCGGC GCTCAGCAAG TTTATCGCCG TCTACTTTGA TTATTCCTGC 
GAGGGAGACG TCCCCGGTAT CCTAGACCTG AGTACCAAGT ACAGACTCAT GGACAATCTT 
CCTCAGCTCT GTTCCCACTT GCACTCCCGA GACCACGGCC TCCAGGAGCC GGGGCAGCAC 
ACGCGACAGG GCAGCAGAAG GAACTACTTC CGGAGCAAGT CAGGCCGGTC CCTATACGTC 
GCCATTTGCA ACATGCACCA GTTTATTGAC GAGGAGCCCG ACTGGTTCGA AAAGCAGTTC 
GTTCCCTTCC ATCCTCCTCC ACTGCGCTAC CGGGAGCCAG TCTTGGAGAA ATTTGATTCG 
GGCTTGGTTT TAAATGATGT CATGTGCAAA CCAGGGCCTG AGAGTGACTT CTGCCTAAAG 
GTAGAGGCGG CTGTTCTTGG GGCAACCGGA CCAGCCGACT CCCAGCACGA GAGTCAGCAT 
GGGGGCCTGG ACCAAGACGG GGAGGCCCGG CCTGCCCTTG ACGGTAGCGC CGCCCTGCAA 
CCCCTGCTGC ACACGGTGAA AGCCGGCAGC CCCTCGGACA TGCCGCGGGA CTCAGGCATC 
TATGACTCGT CTGTGCCCTC ATCCGAGCTG TCTCTGCCAC TGATGGAAGG ACTCTCGACG 
GACCAGACAG AAACGTCTTC CCTGACGGAG AGCGTGTCCT CCTCTTCAGG CCTGGGTGAG 
GAGGAACCTC CTGCCCTTCC TTCCAAGCTC CTCTCTTCTG GGTCATGCAA AGCAGATCTT 
GGTTGCCGCA GCTACACTGA TGAACTCCAC GCGGTCGCCC CTTTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IL17RD ( XM_011533849.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011532151.2 Homo sapiens interleukin 17 receptor D (IL17RD), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu37307
Clone ID Related Accession (Same CDS sequence)	XM_011533849.2 , XM_006713209.3 , NM_001318864.1
Accession Version	XM_011533849.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1788bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	interleukin-17 receptor D isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011533849.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAATCTC AACCTTTCCT GAATATGAAA TTTGAAACGG ATTATTTCGT AAAGGTTGTC 
CCTTTTCCTT CCATTAAAAA CGAAAGCAAT TACCACCCTT TCTTCTTTAG AACCCGAGCC 
TGTGACCTGT TGTTACAGCC GGACAATCTA GCTTGTAAAC CCTTCTGGAA GCCTCGGAAC 
CTGAACATCA GCCAGCATGG CTCGGACATG CAGGTGTCCT TCGACCATGC ACCGCACAAC 
TTCGGCTTCC GTTTCTTCTA TCTTCACTAC AAGCTCAAGC ACGAAGGACC TTTCAAGCGA 
AAGACCTGTA AGCAGGAGCA AACTACAGAG ACGACCAGCT GCCTCCTTCA AAATGTTTCT 
CCAGGGGATT ATATAATTGA GCTGGTGGAT GACACTAACA CAACAAGAAA AGTGATGCAT 
TATGCCTTAA AGCCAGTGCA CTCCCCGTGG GCCGGGCCCA TCAGAGCCGT GGCCATCACA 
GTGCCACTGG TAGTCATATC GGCATTCGCG ACGCTCTTCA CTGTGATGTG CCGCAAGAAG 
CAACAAGAAA ATATATATTC ACATTTAGAT GAAGAGAGCT CTGAGTCTTC CACATACACT 
GCAGCACTCC CAAGAGAGAG GCTCCGGCCG CGGCCGAAGG TCTTTCTCTG CTATTCCAGT 
AAAGATGGCC AGAATCACAT GAATGTCGTC CAGTGTTTCG CCTACTTCCT CCAGGACTTC 
TGTGGCTGTG AGGTGGCTCT GGACCTGTGG GAAGACTTCA GCCTCTGTAG AGAAGGGCAG 
AGAGAATGGG TCATCCAGAA GATCCACGAG TCCCAGTTCA TCATTGTGGT TTGTTCCAAA 
GGTATGAAGT ACTTTGTGGA CAAGAAGAAC TACAAACACA AAGGAGGTGG CCGAGGCTCG 
GGGAAAGGAG AGCTCTTCCT GGTGGCGGTG TCAGCCATTG CCGAAAAGCT CCGCCAGGCC 
AAGCAGAGTT CGTCCGCGGC GCTCAGCAAG TTTATCGCCG TCTACTTTGA TTATTCCTGC 
GAGGGAGACG TCCCCGGTAT CCTAGACCTG AGTACCAAGT ACAGACTCAT GGACAATCTT 
CCTCAGCTCT GTTCCCACTT GCACTCCCGA GACCACGGCC TCCAGGAGCC GGGGCAGCAC 
ACGCGACAGG GCAGCAGAAG GAACTACTTC CGGAGCAAGT CAGGCCGGTC CCTATACGTC 
GCCATTTGCA ACATGCACCA GTTTATTGAC GAGGAGCCCG ACTGGTTCGA AAAGCAGTTC 
GTTCCCTTCC ATCCTCCTCC ACTGCGCTAC CGGGAGCCAG TCTTGGAGAA ATTTGATTCG 
GGCTTGGTTT TAAATGATGT CATGTGCAAA CCAGGGCCTG AGAGTGACTT CTGCCTAAAG 
GTAGAGGCGG CTGTTCTTGG GGCAACCGGA CCAGCCGACT CCCAGCACGA GAGTCAGCAT 
GGGGGCCTGG ACCAAGACGG GGAGGCCCGG CCTGCCCTTG ACGGTAGCGC CGCCCTGCAA 
CCCCTGCTGC ACACGGTGAA AGCCGGCAGC CCCTCGGACA TGCCGCGGGA CTCAGGCATC 
TATGACTCGT CTGTGCCCTC ATCCGAGCTG TCTCTGCCAC TGATGGAAGG ACTCTCGACG 
GACCAGACAG AAACGTCTTC CCTGACGGAG AGCGTGTCCT CCTCTTCAGG CCTGGGTGAG 
GAGGAACCTC CTGCCCTTCC TTCCAAGCTC CTCTCTTCTG GGTCATGCAA AGCAGATCTT 
GGTTGCCGCA GCTACACTGA TGAACTCCAC GCGGTCGCCC CTTTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011532151.2
CDS	341..2128
Translation	MESQPFLNMKFETDYFVKVVPFPSIKNESNYHPFFFRTRACDLLLQPDNLACKPFWKPRNLNISQHGSDMQVSFDHAPHNFGFRFFYLHYKLKHEGPFKRKTCKQEQTTETTSCLLQNVSPGDYIIELVDDTNTTRKVMHYALKPVHSPWAGPIRAVAITVPLVVISAFATLFTVMCRKKQQENIYSHLDEESSESSTYTAALPRERLRPRPKVFLCYSSKDGQNHMNVVQCFAYFLQDFCGCEVALDLWEDFSLCREGQREWVIQKIHESQFIIVVCSKGMKYFVDKKNYKHKGGGRGSGKGELFLVAVSAIAEKLRQAKQSSSAALSKFIAVYFDYSCEGDVPGILDLSTKYRLMDNLPQLCSHLHSRDHGLQEPGQHTRQGSRRNYFRSKSGRSLYVAICNMHQFIDEEPDWFEKQFVPFHPPPLRYREPVLEKFDSGLVLNDVMCKPGPESDFCLKVEAAVLGATGPADSQHESQHGGLDQDGEARPALDGSAALQPLLHTVKAGSPSDMPRDSGIYDSSVPSSELSLPLMEGLSTDQTETSSLTESVSSSSGLGEEEPPALPSKLLSSGSCKADLGCRSYTDELHAVAPL

Target ORF information:

RefSeq Version	XM_011533849.2
Organism	Homo sapiens(human)
Definition	Homo sapiens interleukin 17 receptor D (IL17RD), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011533849.2

ORF Insert Sequence:

ATGGAATCTC AACCTTTCCT GAATATGAAA TTTGAAACGG ATTATTTCGT AAAGGTTGTC 
CCTTTTCCTT CCATTAAAAA CGAAAGCAAT TACCACCCTT TCTTCTTTAG AACCCGAGCC 
TGTGACCTGT TGTTACAGCC GGACAATCTA GCTTGTAAAC CCTTCTGGAA GCCTCGGAAC 
CTGAACATCA GCCAGCATGG CTCGGACATG CAGGTGTCCT TCGACCATGC ACCGCACAAC 
TTCGGCTTCC GTTTCTTCTA TCTTCACTAC AAGCTCAAGC ACGAAGGACC TTTCAAGCGA 
AAGACCTGTA AGCAGGAGCA AACTACAGAG ACGACCAGCT GCCTCCTTCA AAATGTTTCT 
CCAGGGGATT ATATAATTGA GCTGGTGGAT GACACTAACA CAACAAGAAA AGTGATGCAT 
TATGCCTTAA AGCCAGTGCA CTCCCCGTGG GCCGGGCCCA TCAGAGCCGT GGCCATCACA 
GTGCCACTGG TAGTCATATC GGCATTCGCG ACGCTCTTCA CTGTGATGTG CCGCAAGAAG 
CAACAAGAAA ATATATATTC ACATTTAGAT GAAGAGAGCT CTGAGTCTTC CACATACACT 
GCAGCACTCC CAAGAGAGAG GCTCCGGCCG CGGCCGAAGG TCTTTCTCTG CTATTCCAGT 
AAAGATGGCC AGAATCACAT GAATGTCGTC CAGTGTTTCG CCTACTTCCT CCAGGACTTC 
TGTGGCTGTG AGGTGGCTCT GGACCTGTGG GAAGACTTCA GCCTCTGTAG AGAAGGGCAG 
AGAGAATGGG TCATCCAGAA GATCCACGAG TCCCAGTTCA TCATTGTGGT TTGTTCCAAA 
GGTATGAAGT ACTTTGTGGA CAAGAAGAAC TACAAACACA AAGGAGGTGG CCGAGGCTCG 
GGGAAAGGAG AGCTCTTCCT GGTGGCGGTG TCAGCCATTG CCGAAAAGCT CCGCCAGGCC 
AAGCAGAGTT CGTCCGCGGC GCTCAGCAAG TTTATCGCCG TCTACTTTGA TTATTCCTGC 
GAGGGAGACG TCCCCGGTAT CCTAGACCTG AGTACCAAGT ACAGACTCAT GGACAATCTT 
CCTCAGCTCT GTTCCCACTT GCACTCCCGA GACCACGGCC TCCAGGAGCC GGGGCAGCAC 
ACGCGACAGG GCAGCAGAAG GAACTACTTC CGGAGCAAGT CAGGCCGGTC CCTATACGTC 
GCCATTTGCA ACATGCACCA GTTTATTGAC GAGGAGCCCG ACTGGTTCGA AAAGCAGTTC 
GTTCCCTTCC ATCCTCCTCC ACTGCGCTAC CGGGAGCCAG TCTTGGAGAA ATTTGATTCG 
GGCTTGGTTT TAAATGATGT CATGTGCAAA CCAGGGCCTG AGAGTGACTT CTGCCTAAAG 
GTAGAGGCGG CTGTTCTTGG GGCAACCGGA CCAGCCGACT CCCAGCACGA GAGTCAGCAT 
GGGGGCCTGG ACCAAGACGG GGAGGCCCGG CCTGCCCTTG ACGGTAGCGC CGCCCTGCAA 
CCCCTGCTGC ACACGGTGAA AGCCGGCAGC CCCTCGGACA TGCCGCGGGA CTCAGGCATC 
TATGACTCGT CTGTGCCCTC ATCCGAGCTG TCTCTGCCAC TGATGGAAGG ACTCTCGACG 
GACCAGACAG AAACGTCTTC CCTGACGGAG AGCGTGTCCT CCTCTTCAGG CCTGGGTGAG 
GAGGAACCTC CTGCCCTTCC TTCCAAGCTC CTCTCTTCTG GGTCATGCAA AGCAGATCTT 
GGTTGCCGCA GCTACACTGA TGAACTCCAC GCGGTCGCCC CTTTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IL17RD ( XM_006713209.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_006713272.1 Homo sapiens interleukin 17 receptor D (IL17RD), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu37307
Clone ID Related Accession (Same CDS sequence)	XM_011533849.2 , XM_006713209.3 , NM_001318864.1
Accession Version	XM_006713209.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1788bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	interleukin-17 receptor D isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006713209.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAATCTC AACCTTTCCT GAATATGAAA TTTGAAACGG ATTATTTCGT AAAGGTTGTC 
CCTTTTCCTT CCATTAAAAA CGAAAGCAAT TACCACCCTT TCTTCTTTAG AACCCGAGCC 
TGTGACCTGT TGTTACAGCC GGACAATCTA GCTTGTAAAC CCTTCTGGAA GCCTCGGAAC 
CTGAACATCA GCCAGCATGG CTCGGACATG CAGGTGTCCT TCGACCATGC ACCGCACAAC 
TTCGGCTTCC GTTTCTTCTA TCTTCACTAC AAGCTCAAGC ACGAAGGACC TTTCAAGCGA 
AAGACCTGTA AGCAGGAGCA AACTACAGAG ACGACCAGCT GCCTCCTTCA AAATGTTTCT 
CCAGGGGATT ATATAATTGA GCTGGTGGAT GACACTAACA CAACAAGAAA AGTGATGCAT 
TATGCCTTAA AGCCAGTGCA CTCCCCGTGG GCCGGGCCCA TCAGAGCCGT GGCCATCACA 
GTGCCACTGG TAGTCATATC GGCATTCGCG ACGCTCTTCA CTGTGATGTG CCGCAAGAAG 
CAACAAGAAA ATATATATTC ACATTTAGAT GAAGAGAGCT CTGAGTCTTC CACATACACT 
GCAGCACTCC CAAGAGAGAG GCTCCGGCCG CGGCCGAAGG TCTTTCTCTG CTATTCCAGT 
AAAGATGGCC AGAATCACAT GAATGTCGTC CAGTGTTTCG CCTACTTCCT CCAGGACTTC 
TGTGGCTGTG AGGTGGCTCT GGACCTGTGG GAAGACTTCA GCCTCTGTAG AGAAGGGCAG 
AGAGAATGGG TCATCCAGAA GATCCACGAG TCCCAGTTCA TCATTGTGGT TTGTTCCAAA 
GGTATGAAGT ACTTTGTGGA CAAGAAGAAC TACAAACACA AAGGAGGTGG CCGAGGCTCG 
GGGAAAGGAG AGCTCTTCCT GGTGGCGGTG TCAGCCATTG CCGAAAAGCT CCGCCAGGCC 
AAGCAGAGTT CGTCCGCGGC GCTCAGCAAG TTTATCGCCG TCTACTTTGA TTATTCCTGC 
GAGGGAGACG TCCCCGGTAT CCTAGACCTG AGTACCAAGT ACAGACTCAT GGACAATCTT 
CCTCAGCTCT GTTCCCACTT GCACTCCCGA GACCACGGCC TCCAGGAGCC GGGGCAGCAC 
ACGCGACAGG GCAGCAGAAG GAACTACTTC CGGAGCAAGT CAGGCCGGTC CCTATACGTC 
GCCATTTGCA ACATGCACCA GTTTATTGAC GAGGAGCCCG ACTGGTTCGA AAAGCAGTTC 
GTTCCCTTCC ATCCTCCTCC ACTGCGCTAC CGGGAGCCAG TCTTGGAGAA ATTTGATTCG 
GGCTTGGTTT TAAATGATGT CATGTGCAAA CCAGGGCCTG AGAGTGACTT CTGCCTAAAG 
GTAGAGGCGG CTGTTCTTGG GGCAACCGGA CCAGCCGACT CCCAGCACGA GAGTCAGCAT 
GGGGGCCTGG ACCAAGACGG GGAGGCCCGG CCTGCCCTTG ACGGTAGCGC CGCCCTGCAA 
CCCCTGCTGC ACACGGTGAA AGCCGGCAGC CCCTCGGACA TGCCGCGGGA CTCAGGCATC 
TATGACTCGT CTGTGCCCTC ATCCGAGCTG TCTCTGCCAC TGATGGAAGG ACTCTCGACG 
GACCAGACAG AAACGTCTTC CCTGACGGAG AGCGTGTCCT CCTCTTCAGG CCTGGGTGAG 
GAGGAACCTC CTGCCCTTCC TTCCAAGCTC CTCTCTTCTG GGTCATGCAA AGCAGATCTT 
GGTTGCCGCA GCTACACTGA TGAACTCCAC GCGGTCGCCC CTTTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006713272.1
CDS	684..2471
Translation	MESQPFLNMKFETDYFVKVVPFPSIKNESNYHPFFFRTRACDLLLQPDNLACKPFWKPRNLNISQHGSDMQVSFDHAPHNFGFRFFYLHYKLKHEGPFKRKTCKQEQTTETTSCLLQNVSPGDYIIELVDDTNTTRKVMHYALKPVHSPWAGPIRAVAITVPLVVISAFATLFTVMCRKKQQENIYSHLDEESSESSTYTAALPRERLRPRPKVFLCYSSKDGQNHMNVVQCFAYFLQDFCGCEVALDLWEDFSLCREGQREWVIQKIHESQFIIVVCSKGMKYFVDKKNYKHKGGGRGSGKGELFLVAVSAIAEKLRQAKQSSSAALSKFIAVYFDYSCEGDVPGILDLSTKYRLMDNLPQLCSHLHSRDHGLQEPGQHTRQGSRRNYFRSKSGRSLYVAICNMHQFIDEEPDWFEKQFVPFHPPPLRYREPVLEKFDSGLVLNDVMCKPGPESDFCLKVEAAVLGATGPADSQHESQHGGLDQDGEARPALDGSAALQPLLHTVKAGSPSDMPRDSGIYDSSVPSSELSLPLMEGLSTDQTETSSLTESVSSSSGLGEEEPPALPSKLLSSGSCKADLGCRSYTDELHAVAPL

Target ORF information:

RefSeq Version	XM_006713209.3
Organism	Homo sapiens(human)
Definition	Homo sapiens interleukin 17 receptor D (IL17RD), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006713209.3

ORF Insert Sequence:

ATGGAATCTC AACCTTTCCT GAATATGAAA TTTGAAACGG ATTATTTCGT AAAGGTTGTC 
CCTTTTCCTT CCATTAAAAA CGAAAGCAAT TACCACCCTT TCTTCTTTAG AACCCGAGCC 
TGTGACCTGT TGTTACAGCC GGACAATCTA GCTTGTAAAC CCTTCTGGAA GCCTCGGAAC 
CTGAACATCA GCCAGCATGG CTCGGACATG CAGGTGTCCT TCGACCATGC ACCGCACAAC 
TTCGGCTTCC GTTTCTTCTA TCTTCACTAC AAGCTCAAGC ACGAAGGACC TTTCAAGCGA 
AAGACCTGTA AGCAGGAGCA AACTACAGAG ACGACCAGCT GCCTCCTTCA AAATGTTTCT 
CCAGGGGATT ATATAATTGA GCTGGTGGAT GACACTAACA CAACAAGAAA AGTGATGCAT 
TATGCCTTAA AGCCAGTGCA CTCCCCGTGG GCCGGGCCCA TCAGAGCCGT GGCCATCACA 
GTGCCACTGG TAGTCATATC GGCATTCGCG ACGCTCTTCA CTGTGATGTG CCGCAAGAAG 
CAACAAGAAA ATATATATTC ACATTTAGAT GAAGAGAGCT CTGAGTCTTC CACATACACT 
GCAGCACTCC CAAGAGAGAG GCTCCGGCCG CGGCCGAAGG TCTTTCTCTG CTATTCCAGT 
AAAGATGGCC AGAATCACAT GAATGTCGTC CAGTGTTTCG CCTACTTCCT CCAGGACTTC 
TGTGGCTGTG AGGTGGCTCT GGACCTGTGG GAAGACTTCA GCCTCTGTAG AGAAGGGCAG 
AGAGAATGGG TCATCCAGAA GATCCACGAG TCCCAGTTCA TCATTGTGGT TTGTTCCAAA 
GGTATGAAGT ACTTTGTGGA CAAGAAGAAC TACAAACACA AAGGAGGTGG CCGAGGCTCG 
GGGAAAGGAG AGCTCTTCCT GGTGGCGGTG TCAGCCATTG CCGAAAAGCT CCGCCAGGCC 
AAGCAGAGTT CGTCCGCGGC GCTCAGCAAG TTTATCGCCG TCTACTTTGA TTATTCCTGC 
GAGGGAGACG TCCCCGGTAT CCTAGACCTG AGTACCAAGT ACAGACTCAT GGACAATCTT 
CCTCAGCTCT GTTCCCACTT GCACTCCCGA GACCACGGCC TCCAGGAGCC GGGGCAGCAC 
ACGCGACAGG GCAGCAGAAG GAACTACTTC CGGAGCAAGT CAGGCCGGTC CCTATACGTC 
GCCATTTGCA ACATGCACCA GTTTATTGAC GAGGAGCCCG ACTGGTTCGA AAAGCAGTTC 
GTTCCCTTCC ATCCTCCTCC ACTGCGCTAC CGGGAGCCAG TCTTGGAGAA ATTTGATTCG 
GGCTTGGTTT TAAATGATGT CATGTGCAAA CCAGGGCCTG AGAGTGACTT CTGCCTAAAG 
GTAGAGGCGG CTGTTCTTGG GGCAACCGGA CCAGCCGACT CCCAGCACGA GAGTCAGCAT 
GGGGGCCTGG ACCAAGACGG GGAGGCCCGG CCTGCCCTTG ACGGTAGCGC CGCCCTGCAA 
CCCCTGCTGC ACACGGTGAA AGCCGGCAGC CCCTCGGACA TGCCGCGGGA CTCAGGCATC 
TATGACTCGT CTGTGCCCTC ATCCGAGCTG TCTCTGCCAC TGATGGAAGG ACTCTCGACG 
GACCAGACAG AAACGTCTTC CCTGACGGAG AGCGTGTCCT CCTCTTCAGG CCTGGGTGAG 
GAGGAACCTC CTGCCCTTCC TTCCAAGCTC CTCTCTTCTG GGTCATGCAA AGCAGATCTT 
GGTTGCCGCA GCTACACTGA TGAACTCCAC GCGGTCGCCC CTTTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IL17RD ( NM_017563.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_060033.3 Homo sapiens interleukin 17 receptor D (IL17RD), transcript variant 2, mRNA.

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CloneID	OHu09609
Clone ID Related Accession (Same CDS sequence)	NM_017563.5 , NM_017563.4
Accession Version	NM_017563.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2220bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-21
Organism	Homo sapiens(human)
Product	interleukin-17 receptor D isoform a precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY024286.1, AF458067.1, AK302045.1, AC097358.2 and BQ017683.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_017563.4. Transcript Variant: This variant (2) represents the shorter transcript and encodes the longer isoform a (also known as hSef-a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF494208.1, SRR1803615.154012.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1966682, SAMEA1968189 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000296318.12/ ENSP00000296318.7 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCCCGT GGCTGCAGCT CTGCTCCGTC TTCTTTACGG TCAACGCCTG CCTCAACGGC 
TCGCAGCTGG CTGTGGCCGC TGGCGGGTCC GGCCGCGCGC GGGGCGCCGA CACCTGTGGC 
TGGAGGGGAG TGGGGCCAGC CAGCAGAAAC AGTGGGCTGT ACAACATCAC CTTCAAATAT 
GACAATTGTA CCACCTACTT GAATCCAGTG GGGAAGCATG TGATTGCTGA CGCCCAGAAT 
ATCACCATCA GCCAGTATGC TTGCCATGAC CAAGTGGCAG TCACCATTCT TTGGTCCCCA 
GGGGCCCTCG GCATCGAATT CCTGAAAGGA TTTCGGGTAA TACTGGAGGA GCTGAAGTCG 
GAGGGAAGAC AGTGCCAACA ACTGATTCTA AAGGATCCGA AGCAGCTCAA CAGTAGCTTC 
AAAAGAACTG GAATGGAATC TCAACCTTTC CTGAATATGA AATTTGAAAC GGATTATTTC 
GTAAAGGTTG TCCCTTTTCC TTCCATTAAA AACGAAAGCA ATTACCACCC TTTCTTCTTT 
AGAACCCGAG CCTGTGACCT GTTGTTACAG CCGGACAATC TAGCTTGTAA ACCCTTCTGG 
AAGCCTCGGA ACCTGAACAT CAGCCAGCAT GGCTCGGACA TGCAGGTGTC CTTCGACCAT 
GCACCGCACA ACTTCGGCTT CCGTTTCTTC TATCTTCACT ACAAGCTCAA GCACGAAGGA 
CCTTTCAAGC GAAAGACCTG TAAGCAGGAG CAAACTACAG AGACGACCAG CTGCCTCCTT 
CAAAATGTTT CTCCAGGGGA TTATATAATT GAGCTGGTGG ATGACACTAA CACAACAAGA 
AAAGTGATGC ATTATGCCTT AAAGCCAGTG CACTCCCCGT GGGCCGGGCC CATCAGAGCC 
GTGGCCATCA CAGTGCCACT GGTAGTCATA TCGGCATTCG CGACGCTCTT CACTGTGATG 
TGCCGCAAGA AGCAACAAGA AAATATATAT TCACATTTAG ATGAAGAGAG CTCTGAGTCT 
TCCACATACA CTGCAGCACT CCCAAGAGAG AGGCTCCGGC CGCGGCCGAA GGTCTTTCTC 
TGCTATTCCA GTAAAGATGG CCAGAATCAC ATGAATGTCG TCCAGTGTTT CGCCTACTTC 
CTCCAGGACT TCTGTGGCTG TGAGGTGGCT CTGGACCTGT GGGAAGACTT CAGCCTCTGT 
AGAGAAGGGC AGAGAGAATG GGTCATCCAG AAGATCCACG AGTCCCAGTT CATCATTGTG 
GTTTGTTCCA AAGGTATGAA GTACTTTGTG GACAAGAAGA ACTACAAACA CAAAGGAGGT 
GGCCGAGGCT CGGGGAAAGG AGAGCTCTTC CTGGTGGCGG TGTCAGCCAT TGCCGAAAAG 
CTCCGCCAGG CCAAGCAGAG TTCGTCCGCG GCGCTCAGCA AGTTTATCGC CGTCTACTTT 
GATTATTCCT GCGAGGGAGA CGTCCCCGGT ATCCTAGACC TGAGTACCAA GTACAGACTC 
ATGGACAATC TTCCTCAGCT CTGTTCCCAC TTGCACTCCC GAGACCACGG CCTCCAGGAG 
CCGGGGCAGC ACACGCGACA GGGCAGCAGA AGGAACTACT TCCGGAGCAA GTCAGGCCGG 
TCCCTATACG TCGCCATTTG CAACATGCAC CAGTTTATTG ACGAGGAGCC CGACTGGTTC 
GAAAAGCAGT TCGTTCCCTT CCATCCTCCT CCACTGCGCT ACCGGGAGCC AGTCTTGGAG 
AAATTTGATT CGGGCTTGGT TTTAAATGAT GTCATGTGCA AACCAGGGCC TGAGAGTGAC 
TTCTGCCTAA AGGTAGAGGC GGCTGTTCTT GGGGCAACCG GACCAGCCGA CTCCCAGCAC 
GAGAGTCAGC ATGGGGGCCT GGACCAAGAC GGGGAGGCCC GGCCTGCCCT TGACGGTAGC 
GCCGCCCTGC AACCCCTGCT GCACACGGTG AAAGCCGGCA GCCCCTCGGA CATGCCGCGG 
GACTCAGGCA TCTATGACTC GTCTGTGCCC TCATCCGAGC TGTCTCTGCC ACTGATGGAA 
GGACTCTCGA CGGACCAGAC AGAAACGTCT TCCCTGACGG AGAGCGTGTC CTCCTCTTCA 
GGCCTGGGTG AGGAGGAACC TCCTGCCCTT CCTTCCAAGC TCCTCTCTTC TGGGTCATGC 
AAAGCAGATC TTGGTTGCCG CAGCTACACT GATGAACTCC ACGCGGTCGC CCCTTTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060033.3
CDS	68..2287
Translation	MAPWLQLCSVFFTVNACLNGSQLAVAAGGSGRARGADTCGWRGVGPASRNSGLYNITFKYDNCTTYLNPVGKHVIADAQNITISQYACHDQVAVTILWSPGALGIEFLKGFRVILEELKSEGRQCQQLILKDPKQLNSSFKRTGMESQPFLNMKFETDYFVKVVPFPSIKNESNYHPFFFRTRACDLLLQPDNLACKPFWKPRNLNISQHGSDMQVSFDHAPHNFGFRFFYLHYKLKHEGPFKRKTCKQEQTTETTSCLLQNVSPGDYIIELVDDTNTTRKVMHYALKPVHSPWAGPIRAVAITVPLVVISAFATLFTVMCRKKQQENIYSHLDEESSESSTYTAALPRERLRPRPKVFLCYSSKDGQNHMNVVQCFAYFLQDFCGCEVALDLWEDFSLCREGQREWVIQKIHESQFIIVVCSKGMKYFVDKKNYKHKGGGRGSGKGELFLVAVSAIAEKLRQAKQSSSAALSKFIAVYFDYSCEGDVPGILDLSTKYRLMDNLPQLCSHLHSRDHGLQEPGQHTRQGSRRNYFRSKSGRSLYVAICNMHQFIDEEPDWFEKQFVPFHPPPLRYREPVLEKFDSGLVLNDVMCKPGPESDFCLKVEAAVLGATGPADSQHESQHGGLDQDGEARPALDGSAALQPLLHTVKAGSPSDMPRDSGIYDSSVPSSELSLPLMEGLSTDQTETSSLTESVSSSSGLGEEEPPALPSKLLSSGSCKADLGCRSYTDELHAVAPL

Target ORF information:

RefSeq Version	NM_017563.5
Organism	Homo sapiens(human)
Definition	Homo sapiens interleukin 17 receptor D (IL17RD), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017563.5

ORF Insert Sequence:

ATGGCCCCGT GGCTGCAGCT CTGCTCCGTC TTCTTTACGG TCAACGCCTG CCTCAACGGC 
TCGCAGCTGG CTGTGGCCGC TGGCGGGTCC GGCCGCGCGC GGGGCGCCGA CACCTGTGGC 
TGGAGGGGAG TGGGGCCAGC CAGCAGAAAC AGTGGGCTGT ACAACATCAC CTTCAAATAT 
GACAATTGTA CCACCTACTT GAATCCAGTG GGGAAGCATG TGATTGCTGA CGCCCAGAAT 
ATCACCATCA GCCAGTATGC TTGCCATGAC CAAGTGGCAG TCACCATTCT TTGGTCCCCA 
GGGGCCCTCG GCATCGAATT CCTGAAAGGA TTTCGGGTAA TACTGGAGGA GCTGAAGTCG 
GAGGGAAGAC AGTGCCAACA ACTGATTCTA AAGGATCCGA AGCAGCTCAA CAGTAGCTTC 
AAAAGAACTG GAATGGAATC TCAACCTTTC CTGAATATGA AATTTGAAAC GGATTATTTC 
GTAAAGGTTG TCCCTTTTCC TTCCATTAAA AACGAAAGCA ATTACCACCC TTTCTTCTTT 
AGAACCCGAG CCTGTGACCT GTTGTTACAG CCGGACAATC TAGCTTGTAA ACCCTTCTGG 
AAGCCTCGGA ACCTGAACAT CAGCCAGCAT GGCTCGGACA TGCAGGTGTC CTTCGACCAT 
GCACCGCACA ACTTCGGCTT CCGTTTCTTC TATCTTCACT ACAAGCTCAA GCACGAAGGA 
CCTTTCAAGC GAAAGACCTG TAAGCAGGAG CAAACTACAG AGACGACCAG CTGCCTCCTT 
CAAAATGTTT CTCCAGGGGA TTATATAATT GAGCTGGTGG ATGACACTAA CACAACAAGA 
AAAGTGATGC ATTATGCCTT AAAGCCAGTG CACTCCCCGT GGGCCGGGCC CATCAGAGCC 
GTGGCCATCA CAGTGCCACT GGTAGTCATA TCGGCATTCG CGACGCTCTT CACTGTGATG 
TGCCGCAAGA AGCAACAAGA AAATATATAT TCACATTTAG ATGAAGAGAG CTCTGAGTCT 
TCCACATACA CTGCAGCACT CCCAAGAGAG AGGCTCCGGC CGCGGCCGAA GGTCTTTCTC 
TGCTATTCCA GTAAAGATGG CCAGAATCAC ATGAATGTCG TCCAGTGTTT CGCCTACTTC 
CTCCAGGACT TCTGTGGCTG TGAGGTGGCT CTGGACCTGT GGGAAGACTT CAGCCTCTGT 
AGAGAAGGGC AGAGAGAATG GGTCATCCAG AAGATCCACG AGTCCCAGTT CATCATTGTG 
GTTTGTTCCA AAGGTATGAA GTACTTTGTG GACAAGAAGA ACTACAAACA CAAAGGAGGT 
GGCCGAGGCT CGGGGAAAGG AGAGCTCTTC CTGGTGGCGG TGTCAGCCAT TGCCGAAAAG 
CTCCGCCAGG CCAAGCAGAG TTCGTCCGCG GCGCTCAGCA AGTTTATCGC CGTCTACTTT 
GATTATTCCT GCGAGGGAGA CGTCCCCGGT ATCCTAGACC TGAGTACCAA GTACAGACTC 
ATGGACAATC TTCCTCAGCT CTGTTCCCAC TTGCACTCCC GAGACCACGG CCTCCAGGAG 
CCGGGGCAGC ACACGCGACA GGGCAGCAGA AGGAACTACT TCCGGAGCAA GTCAGGCCGG 
TCCCTATACG TCGCCATTTG CAACATGCAC CAGTTTATTG ACGAGGAGCC CGACTGGTTC 
GAAAAGCAGT TCGTTCCCTT CCATCCTCCT CCACTGCGCT ACCGGGAGCC AGTCTTGGAG 
AAATTTGATT CGGGCTTGGT TTTAAATGAT GTCATGTGCA AACCAGGGCC TGAGAGTGAC 
TTCTGCCTAA AGGTAGAGGC GGCTGTTCTT GGGGCAACCG GACCAGCCGA CTCCCAGCAC 
GAGAGTCAGC ATGGGGGCCT GGACCAAGAC GGGGAGGCCC GGCCTGCCCT TGACGGTAGC 
GCCGCCCTGC AACCCCTGCT GCACACGGTG AAAGCCGGCA GCCCCTCGGA CATGCCGCGG 
GACTCAGGCA TCTATGACTC GTCTGTGCCC TCATCCGAGC TGTCTCTGCC ACTGATGGAA 
GGACTCTCGA CGGACCAGAC AGAAACGTCT TCCCTGACGG AGAGCGTGTC CTCCTCTTCA 
GGCCTGGGTG AGGAGGAACC TCCTGCCCTT CCTTCCAAGC TCCTCTCTTC TGGGTCATGC 
AAAGCAGATC TTGGTTGCCG CAGCTACACT GATGAACTCC ACGCGGTCGC CCCTTTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IL17RD ( NM_017563.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_060033.3 Homo sapiens interleukin 17 receptor D (IL17RD), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu09609
Clone ID Related Accession (Same CDS sequence)	NM_017563.5 , NM_017563.4
Accession Version	NM_017563.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2220bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-02
Organism	Homo sapiens(human)
Product	interleukin-17 receptor D isoform a precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY024286.1, AF458067.1, AK302045.1, AC097358.2 and BQ017683.1. This sequence is a reference standard in the RefSeqGene project. On Jan 15, 2016 this sequence version replaced NM_017563.3. Transcript Variant: This variant (2) represents the shorter transcript and encodes the longer isoform a (also known as hSef-a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF494208.1, SRR1803615.154012.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1966682, SAMEA1968189 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCCCGT GGCTGCAGCT CTGCTCCGTC TTCTTTACGG TCAACGCCTG CCTCAACGGC 
TCGCAGCTGG CTGTGGCCGC TGGCGGGTCC GGCCGCGCGC GGGGCGCCGA CACCTGTGGC 
TGGAGGGGAG TGGGGCCAGC CAGCAGAAAC AGTGGGCTGT ACAACATCAC CTTCAAATAT 
GACAATTGTA CCACCTACTT GAATCCAGTG GGGAAGCATG TGATTGCTGA CGCCCAGAAT 
ATCACCATCA GCCAGTATGC TTGCCATGAC CAAGTGGCAG TCACCATTCT TTGGTCCCCA 
GGGGCCCTCG GCATCGAATT CCTGAAAGGA TTTCGGGTAA TACTGGAGGA GCTGAAGTCG 
GAGGGAAGAC AGTGCCAACA ACTGATTCTA AAGGATCCGA AGCAGCTCAA CAGTAGCTTC 
AAAAGAACTG GAATGGAATC TCAACCTTTC CTGAATATGA AATTTGAAAC GGATTATTTC 
GTAAAGGTTG TCCCTTTTCC TTCCATTAAA AACGAAAGCA ATTACCACCC TTTCTTCTTT 
AGAACCCGAG CCTGTGACCT GTTGTTACAG CCGGACAATC TAGCTTGTAA ACCCTTCTGG 
AAGCCTCGGA ACCTGAACAT CAGCCAGCAT GGCTCGGACA TGCAGGTGTC CTTCGACCAT 
GCACCGCACA ACTTCGGCTT CCGTTTCTTC TATCTTCACT ACAAGCTCAA GCACGAAGGA 
CCTTTCAAGC GAAAGACCTG TAAGCAGGAG CAAACTACAG AGACGACCAG CTGCCTCCTT 
CAAAATGTTT CTCCAGGGGA TTATATAATT GAGCTGGTGG ATGACACTAA CACAACAAGA 
AAAGTGATGC ATTATGCCTT AAAGCCAGTG CACTCCCCGT GGGCCGGGCC CATCAGAGCC 
GTGGCCATCA CAGTGCCACT GGTAGTCATA TCGGCATTCG CGACGCTCTT CACTGTGATG 
TGCCGCAAGA AGCAACAAGA AAATATATAT TCACATTTAG ATGAAGAGAG CTCTGAGTCT 
TCCACATACA CTGCAGCACT CCCAAGAGAG AGGCTCCGGC CGCGGCCGAA GGTCTTTCTC 
TGCTATTCCA GTAAAGATGG CCAGAATCAC ATGAATGTCG TCCAGTGTTT CGCCTACTTC 
CTCCAGGACT TCTGTGGCTG TGAGGTGGCT CTGGACCTGT GGGAAGACTT CAGCCTCTGT 
AGAGAAGGGC AGAGAGAATG GGTCATCCAG AAGATCCACG AGTCCCAGTT CATCATTGTG 
GTTTGTTCCA AAGGTATGAA GTACTTTGTG GACAAGAAGA ACTACAAACA CAAAGGAGGT 
GGCCGAGGCT CGGGGAAAGG AGAGCTCTTC CTGGTGGCGG TGTCAGCCAT TGCCGAAAAG 
CTCCGCCAGG CCAAGCAGAG TTCGTCCGCG GCGCTCAGCA AGTTTATCGC CGTCTACTTT 
GATTATTCCT GCGAGGGAGA CGTCCCCGGT ATCCTAGACC TGAGTACCAA GTACAGACTC 
ATGGACAATC TTCCTCAGCT CTGTTCCCAC TTGCACTCCC GAGACCACGG CCTCCAGGAG 
CCGGGGCAGC ACACGCGACA GGGCAGCAGA AGGAACTACT TCCGGAGCAA GTCAGGCCGG 
TCCCTATACG TCGCCATTTG CAACATGCAC CAGTTTATTG ACGAGGAGCC CGACTGGTTC 
GAAAAGCAGT TCGTTCCCTT CCATCCTCCT CCACTGCGCT ACCGGGAGCC AGTCTTGGAG 
AAATTTGATT CGGGCTTGGT TTTAAATGAT GTCATGTGCA AACCAGGGCC TGAGAGTGAC 
TTCTGCCTAA AGGTAGAGGC GGCTGTTCTT GGGGCAACCG GACCAGCCGA CTCCCAGCAC 
GAGAGTCAGC ATGGGGGCCT GGACCAAGAC GGGGAGGCCC GGCCTGCCCT TGACGGTAGC 
GCCGCCCTGC AACCCCTGCT GCACACGGTG AAAGCCGGCA GCCCCTCGGA CATGCCGCGG 
GACTCAGGCA TCTATGACTC GTCTGTGCCC TCATCCGAGC TGTCTCTGCC ACTGATGGAA 
GGACTCTCGA CGGACCAGAC AGAAACGTCT TCCCTGACGG AGAGCGTGTC CTCCTCTTCA 
GGCCTGGGTG AGGAGGAACC TCCTGCCCTT CCTTCCAAGC TCCTCTCTTC TGGGTCATGC 
AAAGCAGATC TTGGTTGCCG CAGCTACACT GATGAACTCC ACGCGGTCGC CCCTTTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060033.3
CDS	114..2333
Translation	MAPWLQLCSVFFTVNACLNGSQLAVAAGGSGRARGADTCGWRGVGPASRNSGLYNITFKYDNCTTYLNPVGKHVIADAQNITISQYACHDQVAVTILWSPGALGIEFLKGFRVILEELKSEGRQCQQLILKDPKQLNSSFKRTGMESQPFLNMKFETDYFVKVVPFPSIKNESNYHPFFFRTRACDLLLQPDNLACKPFWKPRNLNISQHGSDMQVSFDHAPHNFGFRFFYLHYKLKHEGPFKRKTCKQEQTTETTSCLLQNVSPGDYIIELVDDTNTTRKVMHYALKPVHSPWAGPIRAVAITVPLVVISAFATLFTVMCRKKQQENIYSHLDEESSESSTYTAALPRERLRPRPKVFLCYSSKDGQNHMNVVQCFAYFLQDFCGCEVALDLWEDFSLCREGQREWVIQKIHESQFIIVVCSKGMKYFVDKKNYKHKGGGRGSGKGELFLVAVSAIAEKLRQAKQSSSAALSKFIAVYFDYSCEGDVPGILDLSTKYRLMDNLPQLCSHLHSRDHGLQEPGQHTRQGSRRNYFRSKSGRSLYVAICNMHQFIDEEPDWFEKQFVPFHPPPLRYREPVLEKFDSGLVLNDVMCKPGPESDFCLKVEAAVLGATGPADSQHESQHGGLDQDGEARPALDGSAALQPLLHTVKAGSPSDMPRDSGIYDSSVPSSELSLPLMEGLSTDQTETSSLTESVSSSSGLGEEEPPALPSKLLSSGSCKADLGCRSYTDELHAVAPL

Target ORF information:

RefSeq Version	NM_017563.4
Organism	Homo sapiens(human)
Definition	Homo sapiens interleukin 17 receptor D (IL17RD), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017563.4

ORF Insert Sequence:

ATGGCCCCGT GGCTGCAGCT CTGCTCCGTC TTCTTTACGG TCAACGCCTG CCTCAACGGC 
TCGCAGCTGG CTGTGGCCGC TGGCGGGTCC GGCCGCGCGC GGGGCGCCGA CACCTGTGGC 
TGGAGGGGAG TGGGGCCAGC CAGCAGAAAC AGTGGGCTGT ACAACATCAC CTTCAAATAT 
GACAATTGTA CCACCTACTT GAATCCAGTG GGGAAGCATG TGATTGCTGA CGCCCAGAAT 
ATCACCATCA GCCAGTATGC TTGCCATGAC CAAGTGGCAG TCACCATTCT TTGGTCCCCA 
GGGGCCCTCG GCATCGAATT CCTGAAAGGA TTTCGGGTAA TACTGGAGGA GCTGAAGTCG 
GAGGGAAGAC AGTGCCAACA ACTGATTCTA AAGGATCCGA AGCAGCTCAA CAGTAGCTTC 
AAAAGAACTG GAATGGAATC TCAACCTTTC CTGAATATGA AATTTGAAAC GGATTATTTC 
GTAAAGGTTG TCCCTTTTCC TTCCATTAAA AACGAAAGCA ATTACCACCC TTTCTTCTTT 
AGAACCCGAG CCTGTGACCT GTTGTTACAG CCGGACAATC TAGCTTGTAA ACCCTTCTGG 
AAGCCTCGGA ACCTGAACAT CAGCCAGCAT GGCTCGGACA TGCAGGTGTC CTTCGACCAT 
GCACCGCACA ACTTCGGCTT CCGTTTCTTC TATCTTCACT ACAAGCTCAA GCACGAAGGA 
CCTTTCAAGC GAAAGACCTG TAAGCAGGAG CAAACTACAG AGACGACCAG CTGCCTCCTT 
CAAAATGTTT CTCCAGGGGA TTATATAATT GAGCTGGTGG ATGACACTAA CACAACAAGA 
AAAGTGATGC ATTATGCCTT AAAGCCAGTG CACTCCCCGT GGGCCGGGCC CATCAGAGCC 
GTGGCCATCA CAGTGCCACT GGTAGTCATA TCGGCATTCG CGACGCTCTT CACTGTGATG 
TGCCGCAAGA AGCAACAAGA AAATATATAT TCACATTTAG ATGAAGAGAG CTCTGAGTCT 
TCCACATACA CTGCAGCACT CCCAAGAGAG AGGCTCCGGC CGCGGCCGAA GGTCTTTCTC 
TGCTATTCCA GTAAAGATGG CCAGAATCAC ATGAATGTCG TCCAGTGTTT CGCCTACTTC 
CTCCAGGACT TCTGTGGCTG TGAGGTGGCT CTGGACCTGT GGGAAGACTT CAGCCTCTGT 
AGAGAAGGGC AGAGAGAATG GGTCATCCAG AAGATCCACG AGTCCCAGTT CATCATTGTG 
GTTTGTTCCA AAGGTATGAA GTACTTTGTG GACAAGAAGA ACTACAAACA CAAAGGAGGT 
GGCCGAGGCT CGGGGAAAGG AGAGCTCTTC CTGGTGGCGG TGTCAGCCAT TGCCGAAAAG 
CTCCGCCAGG CCAAGCAGAG TTCGTCCGCG GCGCTCAGCA AGTTTATCGC CGTCTACTTT 
GATTATTCCT GCGAGGGAGA CGTCCCCGGT ATCCTAGACC TGAGTACCAA GTACAGACTC 
ATGGACAATC TTCCTCAGCT CTGTTCCCAC TTGCACTCCC GAGACCACGG CCTCCAGGAG 
CCGGGGCAGC ACACGCGACA GGGCAGCAGA AGGAACTACT TCCGGAGCAA GTCAGGCCGG 
TCCCTATACG TCGCCATTTG CAACATGCAC CAGTTTATTG ACGAGGAGCC CGACTGGTTC 
GAAAAGCAGT TCGTTCCCTT CCATCCTCCT CCACTGCGCT ACCGGGAGCC AGTCTTGGAG 
AAATTTGATT CGGGCTTGGT TTTAAATGAT GTCATGTGCA AACCAGGGCC TGAGAGTGAC 
TTCTGCCTAA AGGTAGAGGC GGCTGTTCTT GGGGCAACCG GACCAGCCGA CTCCCAGCAC 
GAGAGTCAGC ATGGGGGCCT GGACCAAGAC GGGGAGGCCC GGCCTGCCCT TGACGGTAGC 
GCCGCCCTGC AACCCCTGCT GCACACGGTG AAAGCCGGCA GCCCCTCGGA CATGCCGCGG 
GACTCAGGCA TCTATGACTC GTCTGTGCCC TCATCCGAGC TGTCTCTGCC ACTGATGGAA 
GGACTCTCGA CGGACCAGAC AGAAACGTCT TCCCTGACGG AGAGCGTGTC CTCCTCTTCA 
GGCCTGGGTG AGGAGGAACC TCCTGCCCTT CCTTCCAAGC TCCTCTCTTC TGGGTCATGC 
AAAGCAGATC TTGGTTGCCG CAGCTACACT GATGAACTCC ACGCGGTCGC CCCTTTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IL17RD ( XM_005265238.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005265295.1 Homo sapiens interleukin 17 receptor D (IL17RD), transcript variant X2, mRNA.

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CloneID	OHu37306
Clone ID Related Accession (Same CDS sequence)	XM_005265238.4
Accession Version	XM_005265238.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2136bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	interleukin-17 receptor D isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005265238.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAAGCGG CTGCCCGACC CCGGCTTTGT GTTGCTAATG AGGGAGTGGG GCCAGCCAGC 
AGAAACAGTG GGCTGTACAA CATCACCTTC AAATATGACA ATTGTACCAC CTACTTGAAT 
CCAGTGGGGA AGCATGTGAT TGCTGACGCC CAGAATATCA CCATCAGCCA GTATGCTTGC 
CATGACCAAG TGGCAGTCAC CATTCTTTGG TCCCCAGGGG CCCTCGGCAT CGAATTCCTG 
AAAGGATTTC GGGTAATACT GGAGGAGCTG AAGTCGGAGG GAAGACAGTG CCAACAACTG 
ATTCTAAAGG ATCCGAAGCA GCTCAACAGT AGCTTCAAAA GAACTGGAAT GGAATCTCAA 
CCTTTCCTGA ATATGAAATT TGAAACGGAT TATTTCGTAA AGGTTGTCCC TTTTCCTTCC 
ATTAAAAACG AAAGCAATTA CCACCCTTTC TTCTTTAGAA CCCGAGCCTG TGACCTGTTG 
TTACAGCCGG ACAATCTAGC TTGTAAACCC TTCTGGAAGC CTCGGAACCT GAACATCAGC 
CAGCATGGCT CGGACATGCA GGTGTCCTTC GACCATGCAC CGCACAACTT CGGCTTCCGT 
TTCTTCTATC TTCACTACAA GCTCAAGCAC GAAGGACCTT TCAAGCGAAA GACCTGTAAG 
CAGGAGCAAA CTACAGAGAC GACCAGCTGC CTCCTTCAAA ATGTTTCTCC AGGGGATTAT 
ATAATTGAGC TGGTGGATGA CACTAACACA ACAAGAAAAG TGATGCATTA TGCCTTAAAG 
CCAGTGCACT CCCCGTGGGC CGGGCCCATC AGAGCCGTGG CCATCACAGT GCCACTGGTA 
GTCATATCGG CATTCGCGAC GCTCTTCACT GTGATGTGCC GCAAGAAGCA ACAAGAAAAT 
ATATATTCAC ATTTAGATGA AGAGAGCTCT GAGTCTTCCA CATACACTGC AGCACTCCCA 
AGAGAGAGGC TCCGGCCGCG GCCGAAGGTC TTTCTCTGCT ATTCCAGTAA AGATGGCCAG 
AATCACATGA ATGTCGTCCA GTGTTTCGCC TACTTCCTCC AGGACTTCTG TGGCTGTGAG 
GTGGCTCTGG ACCTGTGGGA AGACTTCAGC CTCTGTAGAG AAGGGCAGAG AGAATGGGTC 
ATCCAGAAGA TCCACGAGTC CCAGTTCATC ATTGTGGTTT GTTCCAAAGG TATGAAGTAC 
TTTGTGGACA AGAAGAACTA CAAACACAAA GGAGGTGGCC GAGGCTCGGG GAAAGGAGAG 
CTCTTCCTGG TGGCGGTGTC AGCCATTGCC GAAAAGCTCC GCCAGGCCAA GCAGAGTTCG 
TCCGCGGCGC TCAGCAAGTT TATCGCCGTC TACTTTGATT ATTCCTGCGA GGGAGACGTC 
CCCGGTATCC TAGACCTGAG TACCAAGTAC AGACTCATGG ACAATCTTCC TCAGCTCTGT 
TCCCACTTGC ACTCCCGAGA CCACGGCCTC CAGGAGCCGG GGCAGCACAC GCGACAGGGC 
AGCAGAAGGA ACTACTTCCG GAGCAAGTCA GGCCGGTCCC TATACGTCGC CATTTGCAAC 
ATGCACCAGT TTATTGACGA GGAGCCCGAC TGGTTCGAAA AGCAGTTCGT TCCCTTCCAT 
CCTCCTCCAC TGCGCTACCG GGAGCCAGTC TTGGAGAAAT TTGATTCGGG CTTGGTTTTA 
AATGATGTCA TGTGCAAACC AGGGCCTGAG AGTGACTTCT GCCTAAAGGT AGAGGCGGCT 
GTTCTTGGGG CAACCGGACC AGCCGACTCC CAGCACGAGA GTCAGCATGG GGGCCTGGAC 
CAAGACGGGG AGGCCCGGCC TGCCCTTGAC GGTAGCGCCG CCCTGCAACC CCTGCTGCAC 
ACGGTGAAAG CCGGCAGCCC CTCGGACATG CCGCGGGACT CAGGCATCTA TGACTCGTCT 
GTGCCCTCAT CCGAGCTGTC TCTGCCACTG ATGGAAGGAC TCTCGACGGA CCAGACAGAA 
ACGTCTTCCC TGACGGAGAG CGTGTCCTCC TCTTCAGGCC TGGGTGAGGA GGAACCTCCT 
GCCCTTCCTT CCAAGCTCCT CTCTTCTGGG TCATGCAAAG CAGATCTTGG TTGCCGCAGC 
TACACTGATG AACTCCACGC GGTCGCCCCT TTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005265295.1
CDS	409..2544
Translation	MKAAARPRLCVANEGVGPASRNSGLYNITFKYDNCTTYLNPVGKHVIADAQNITISQYACHDQVAVTILWSPGALGIEFLKGFRVILEELKSEGRQCQQLILKDPKQLNSSFKRTGMESQPFLNMKFETDYFVKVVPFPSIKNESNYHPFFFRTRACDLLLQPDNLACKPFWKPRNLNISQHGSDMQVSFDHAPHNFGFRFFYLHYKLKHEGPFKRKTCKQEQTTETTSCLLQNVSPGDYIIELVDDTNTTRKVMHYALKPVHSPWAGPIRAVAITVPLVVISAFATLFTVMCRKKQQENIYSHLDEESSESSTYTAALPRERLRPRPKVFLCYSSKDGQNHMNVVQCFAYFLQDFCGCEVALDLWEDFSLCREGQREWVIQKIHESQFIIVVCSKGMKYFVDKKNYKHKGGGRGSGKGELFLVAVSAIAEKLRQAKQSSSAALSKFIAVYFDYSCEGDVPGILDLSTKYRLMDNLPQLCSHLHSRDHGLQEPGQHTRQGSRRNYFRSKSGRSLYVAICNMHQFIDEEPDWFEKQFVPFHPPPLRYREPVLEKFDSGLVLNDVMCKPGPESDFCLKVEAAVLGATGPADSQHESQHGGLDQDGEARPALDGSAALQPLLHTVKAGSPSDMPRDSGIYDSSVPSSELSLPLMEGLSTDQTETSSLTESVSSSSGLGEEEPPALPSKLLSSGSCKADLGCRSYTDELHAVAPL

Target ORF information:

RefSeq Version	XM_005265238.4
Organism	Homo sapiens(human)
Definition	Homo sapiens interleukin 17 receptor D (IL17RD), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005265238.4

ORF Insert Sequence:

ATGAAAGCGG CTGCCCGACC CCGGCTTTGT GTTGCTAATG AGGGAGTGGG GCCAGCCAGC 
AGAAACAGTG GGCTGTACAA CATCACCTTC AAATATGACA ATTGTACCAC CTACTTGAAT 
CCAGTGGGGA AGCATGTGAT TGCTGACGCC CAGAATATCA CCATCAGCCA GTATGCTTGC 
CATGACCAAG TGGCAGTCAC CATTCTTTGG TCCCCAGGGG CCCTCGGCAT CGAATTCCTG 
AAAGGATTTC GGGTAATACT GGAGGAGCTG AAGTCGGAGG GAAGACAGTG CCAACAACTG 
ATTCTAAAGG ATCCGAAGCA GCTCAACAGT AGCTTCAAAA GAACTGGAAT GGAATCTCAA 
CCTTTCCTGA ATATGAAATT TGAAACGGAT TATTTCGTAA AGGTTGTCCC TTTTCCTTCC 
ATTAAAAACG AAAGCAATTA CCACCCTTTC TTCTTTAGAA CCCGAGCCTG TGACCTGTTG 
TTACAGCCGG ACAATCTAGC TTGTAAACCC TTCTGGAAGC CTCGGAACCT GAACATCAGC 
CAGCATGGCT CGGACATGCA GGTGTCCTTC GACCATGCAC CGCACAACTT CGGCTTCCGT 
TTCTTCTATC TTCACTACAA GCTCAAGCAC GAAGGACCTT TCAAGCGAAA GACCTGTAAG 
CAGGAGCAAA CTACAGAGAC GACCAGCTGC CTCCTTCAAA ATGTTTCTCC AGGGGATTAT 
ATAATTGAGC TGGTGGATGA CACTAACACA ACAAGAAAAG TGATGCATTA TGCCTTAAAG 
CCAGTGCACT CCCCGTGGGC CGGGCCCATC AGAGCCGTGG CCATCACAGT GCCACTGGTA 
GTCATATCGG CATTCGCGAC GCTCTTCACT GTGATGTGCC GCAAGAAGCA ACAAGAAAAT 
ATATATTCAC ATTTAGATGA AGAGAGCTCT GAGTCTTCCA CATACACTGC AGCACTCCCA 
AGAGAGAGGC TCCGGCCGCG GCCGAAGGTC TTTCTCTGCT ATTCCAGTAA AGATGGCCAG 
AATCACATGA ATGTCGTCCA GTGTTTCGCC TACTTCCTCC AGGACTTCTG TGGCTGTGAG 
GTGGCTCTGG ACCTGTGGGA AGACTTCAGC CTCTGTAGAG AAGGGCAGAG AGAATGGGTC 
ATCCAGAAGA TCCACGAGTC CCAGTTCATC ATTGTGGTTT GTTCCAAAGG TATGAAGTAC 
TTTGTGGACA AGAAGAACTA CAAACACAAA GGAGGTGGCC GAGGCTCGGG GAAAGGAGAG 
CTCTTCCTGG TGGCGGTGTC AGCCATTGCC GAAAAGCTCC GCCAGGCCAA GCAGAGTTCG 
TCCGCGGCGC TCAGCAAGTT TATCGCCGTC TACTTTGATT ATTCCTGCGA GGGAGACGTC 
CCCGGTATCC TAGACCTGAG TACCAAGTAC AGACTCATGG ACAATCTTCC TCAGCTCTGT 
TCCCACTTGC ACTCCCGAGA CCACGGCCTC CAGGAGCCGG GGCAGCACAC GCGACAGGGC 
AGCAGAAGGA ACTACTTCCG GAGCAAGTCA GGCCGGTCCC TATACGTCGC CATTTGCAAC 
ATGCACCAGT TTATTGACGA GGAGCCCGAC TGGTTCGAAA AGCAGTTCGT TCCCTTCCAT 
CCTCCTCCAC TGCGCTACCG GGAGCCAGTC TTGGAGAAAT TTGATTCGGG CTTGGTTTTA 
AATGATGTCA TGTGCAAACC AGGGCCTGAG AGTGACTTCT GCCTAAAGGT AGAGGCGGCT 
GTTCTTGGGG CAACCGGACC AGCCGACTCC CAGCACGAGA GTCAGCATGG GGGCCTGGAC 
CAAGACGGGG AGGCCCGGCC TGCCCTTGAC GGTAGCGCCG CCCTGCAACC CCTGCTGCAC 
ACGGTGAAAG CCGGCAGCCC CTCGGACATG CCGCGGGACT CAGGCATCTA TGACTCGTCT 
GTGCCCTCAT CCGAGCTGTC TCTGCCACTG ATGGAAGGAC TCTCGACGGA CCAGACAGAA 
ACGTCTTCCC TGACGGAGAG CGTGTCCTCC TCTTCAGGCC TGGGTGAGGA GGAACCTCCT 
GCCCTTCCTT CCAAGCTCCT CTCTTCTGGG TCATGCAAAG CAGATCTTGG TTGCCGCAGC 
TACACTGATG AACTCCACGC GGTCGCCCCT TTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

miR-193a-3p is a Key Tumor Suppressor in Ulcerative Colitis-Associated Colon Cancer and Promotes Carcinogenesis through Upregulation of IL17RD.
Clinical cancer research : an official journal of the American Association for Cancer Research23(17)5281-5291(2017 Sep)
Pekow J,Meckel K,Dougherty U,Huang Y,Chen X,Almoghrabi A,Mustafi R,Ayaloglu-Butun F,Deng Z,Haider HI,Hart J,Rubin DT,Kwon JH,Bissonnette M

Loss of hSef promotes metastasis through upregulation of EMT in prostate cancer.
International journal of cancer140(8)1881-1887(2017 04)
Hori S,Wadhwa K,Pisupati V,Zecchini V,Ramos-Montoya A,Warren AY,Neal DE,Gnanapragasam VJ

Sef Regulates Epithelial-Mesenchymal Transition in Breast Cancer Cells.
Journal of cellular biochemistry117(10)2346-56(2016 Oct)
He Q,Gong Y,Gower L,Yang X,Friesel RE

Orphan receptor IL-17RD regulates Toll-like receptor signalling via SEFIR/TIR interactions.
Nature communications66669(2015 Mar)
Mellett M,Atzei P,Bergin R,Horgan A,Floss T,Wurst W,Callanan JJ,Moynagh PN

Expression and regulation of the tumor suppressor, SEF, during folliculogenesis in humans and mice.
Reproduction (Cambridge, England)148(5)507-17(2014 Nov)
Lutwak E,Price CA,Abramovich SS,Rabinovitz S,Granot I,Dekel N,Ron D

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IL17RD cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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