CRCT1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CRCT1
Entrez Gene ID	54544
Full Name	cysteine rich C-terminal 1
Synonyms	C1orf42,NICE-1,NICE1
General protein information	Preferred Names cysteine rich C-terminal 1 Names cysteine-rich C-terminal protein 1 protein NICE-1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q21.3
Disorder MIM:	617426

mRNA and Protein(s)

mRNA	Protein	Name
XM_011509656.2	XP_011507958.1	cysteine-rich C-terminal protein 1 isoform X1
NM_019060.3	NP_061933.1	cysteine-rich C-terminal protein 1
NM_019060.2	NP_061933.1	cysteine-rich C-terminal protein 1

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

CRCT1 regulated by microRNA-520?g inhibits proliferation and induces apoptosis in esophageal squamous cell cancer.
Wu N, Song Y, Pang L, Chen Z
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine37(6)8271-9(2016 Jun)

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
Comuzzie AG, Cole SA, Laston SL, Voruganti VS, Haack K, Gibbs RA, Butte NF
PloS one7(12)e51954(2012)

Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.
Torgerson DG, Ampleford EJ, Chiu GY, Gauderman WJ, Gignoux CR, Graves PE, Himes BE, Levin AM, Mathias RA, Hancock DB, Baurley JW, Eng C, Stern DA, Celed?n JC, Rafaels N, Capurso D, Conti DV, Roth LA, Soto-Quiros M, Togias A, Li X, Myers RA, Romieu I, Van Den Berg DJ, Hu D, Hansel NN, Hernandez RD, Israel E, Salam MT, Galanter J, Avila PC, Avila L, Rodriquez-Santana JR, Chapela R, Rodriguez-Cintron W, Diette GB, Adkinson NF, Abel RA, Ross KD, Shi M, Faruque MU, Dunston GM, Watson HR, Mantese VJ, Ezurum SC, Liang L, Ruczinski I, Ford JG, Huntsman S, Chung KF, Vora H, Li X, Calhoun WJ, Castro M, Sienra-Monge JJ, del Rio-Navarro B, Deichmann KA, Heinzmann A, Wenzel SE, Busse WW, Gern JE, Lemanske RF Jr, Beaty TH, Bleecker ER, Raby BA, Meyers DA, London SJ, , Gilliland FD, , Burchard EG, , Martinez FD, , Weiss ST, , Williams LK, , Barnes KC, , Ober C, Nicolae DL
Nature genetics43(9)887-92(2011 Jul)

A human protein-protein interaction network: a resource for annotating the proteome.
Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toks?z E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE
Cell122(6)957-68(2005 Sep)

Identification of human epidermal differentiation complex (EDC)-encoded genes by subtractive hybridization of entire YACs to a gridded keratinocyte cDNA library.
Marenholz I, Zirra M, Fischer DF, Backendorf C, Ziegler A, Mischke D
Genome research11(3)341-55(2001 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

CRCT1 functions as a tumor suppressor gene in ESCC and is regulated by miR-520 g, providing potential therapeutic targets for the treatment of ESCC
Title: CRCT1 regulated by microRNA-520?g inhibits proliferation and induces apoptosis in esophageal squamous cell cancer.

The following CRCT1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CRCT1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu24431	NM_019060.3 Latest version!	Homo sapiens cysteine rich C-terminal 1 (CRCT1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu24431	XM_011509656.2 Latest version!	Homo sapiens cysteine rich C-terminal 1 (CRCT1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
View Old Accession Versions >>
OHu24431	NM_019060.2	Homo sapiens cysteine rich C-terminal 1 (CRCT1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CRCT1 ( NM_019060.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_061933.1 Homo sapiens cysteine rich C-terminal 1 (CRCT1), mRNA.

Price & Availability↑

CloneID	OHu24431
Clone ID Related Accession (Same CDS sequence)	XM_011509656.2 , NM_019060.3 , NM_019060.2
Accession Version	NM_019060.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 300bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-01
Organism	Homo sapiens(human)
Product	cysteine-rich C-terminal protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL135842.15 and AJ243662.1. On Nov 22, 2018 this sequence version replaced NM_019060.2. ##Evidence-Data-START## Transcript exon combination :: ERR279834.11336.1, AJ243662.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000368790.4/ ENSP00000357779.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCCTCTC AACAGAGCGC CGTTTCCGCC AAAGGCTTTT CCAAGGGGTC GTCCCAGGGC 
CCCGCTCCGT GTCCCGCCCC GGCGCCCACC CCGGCGCCCG CCTCCTCCTC CTCCTGCTGC 
GGCTCCGGCA GGGGCTGCTG CGGCGACTCA GGCTGCTGCG GCTCCAGCTC CACCAGTTGC 
TGCTGCTTCC CAAGGAGACG CCGCCGACAG CGGAGTAGTG GTTGCTGCTG CTGCGGGGGC 
GGCAGCCAGA GGTCCCAGCG CTCCAACAAC CGGAGCTCAG GATGCTGCTC CGGCTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061933.1
CDS	94..393
Translation	MSSQQSAVSAKGFSKGSSQGPAPCPAPAPTPAPASSSSCCGSGRGCCGDSGCCGSSSTSCCCFPRRRRRQRSSGCCCCGGGSQRSQRSNNRSSGCCSGC

Target ORF information:

RefSeq Version	NM_019060.3
Organism	Homo sapiens(human)
Definition	Homo sapiens cysteine rich C-terminal 1 (CRCT1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019060.3

ORF Insert Sequence:

ATGTCCTCTC AACAGAGCGC CGTTTCCGCC AAAGGCTTTT CCAAGGGGTC GTCCCAGGGC 
CCCGCTCCGT GTCCCGCCCC GGCGCCCACC CCGGCGCCCG CCTCCTCCTC CTCCTGCTGC 
GGCTCCGGCA GGGGCTGCTG CGGCGACTCA GGCTGCTGCG GCTCCAGCTC CACCAGTTGC 
TGCTGCTTCC CAAGGAGACG CCGCCGACAG CGGAGTAGTG GTTGCTGCTG CTGCGGGGGC 
GGCAGCCAGA GGTCCCAGCG CTCCAACAAC CGGAGCTCAG GATGCTGCTC CGGCTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CRCT1 ( NM_019060.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_061933.1 Homo sapiens cysteine rich C-terminal 1 (CRCT1), mRNA.

Price & Availability↑

CloneID	OHu24431
Clone ID Related Accession (Same CDS sequence)	XM_011509656.2 , NM_019060.3 , NM_019060.2
Accession Version	NM_019060.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 300bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	cysteine-rich C-terminal protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AJ243662.1 and AL135842.15. On Oct 9, 2008 this sequence version replaced NM_019060.1. ##Evidence-Data-START## Transcript exon combination :: AJ243662.1, ERR279834.11336.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END##

ATGTCCTCTC AACAGAGCGC CGTTTCCGCC AAAGGCTTTT CCAAGGGGTC GTCCCAGGGC 
CCCGCTCCGT GTCCCGCCCC GGCGCCCACC CCGGCGCCCG CCTCCTCCTC CTCCTGCTGC 
GGCTCCGGCA GGGGCTGCTG CGGCGACTCA GGCTGCTGCG GCTCCAGCTC CACCAGTTGC 
TGCTGCTTCC CAAGGAGACG CCGCCGACAG CGGAGTAGTG GTTGCTGCTG CTGCGGGGGC 
GGCAGCCAGA GGTCCCAGCG CTCCAACAAC CGGAGCTCAG GATGCTGCTC CGGCTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061933.1
CDS	74..373
Translation	MSSQQSAVSAKGFSKGSSQGPAPCPAPAPTPAPASSSSCCGSGRGCCGDSGCCGSSSTSCCCFPRRRRRQRSSGCCCCGGGSQRSQRSNNRSSGCCSGC

Target ORF information:

RefSeq Version	NM_019060.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cysteine rich C-terminal 1 (CRCT1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019060.2

ORF Insert Sequence:

ATGTCCTCTC AACAGAGCGC CGTTTCCGCC AAAGGCTTTT CCAAGGGGTC GTCCCAGGGC 
CCCGCTCCGT GTCCCGCCCC GGCGCCCACC CCGGCGCCCG CCTCCTCCTC CTCCTGCTGC 
GGCTCCGGCA GGGGCTGCTG CGGCGACTCA GGCTGCTGCG GCTCCAGCTC CACCAGTTGC 
TGCTGCTTCC CAAGGAGACG CCGCCGACAG CGGAGTAGTG GTTGCTGCTG CTGCGGGGGC 
GGCAGCCAGA GGTCCCAGCG CTCCAACAAC CGGAGCTCAG GATGCTGCTC CGGCTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CRCT1 ( XM_011509656.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011507958.1 Homo sapiens cysteine rich C-terminal 1 (CRCT1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu24431
Clone ID Related Accession (Same CDS sequence)	XM_011509656.2 , NM_019060.3 , NM_019060.2
Accession Version	XM_011509656.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 300bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	cysteine-rich C-terminal protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011509656.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCTCTC AACAGAGCGC CGTTTCCGCC AAAGGCTTTT CCAAGGGGTC GTCCCAGGGC 
CCCGCTCCGT GTCCCGCCCC GGCGCCCACC CCGGCGCCCG CCTCCTCCTC CTCCTGCTGC 
GGCTCCGGCA GGGGCTGCTG CGGCGACTCA GGCTGCTGCG GCTCCAGCTC CACCAGTTGC 
TGCTGCTTCC CAAGGAGACG CCGCCGACAG CGGAGTAGTG GTTGCTGCTG CTGCGGGGGC 
GGCAGCCAGA GGTCCCAGCG CTCCAACAAC CGGAGCTCAG GATGCTGCTC CGGCTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011507958.1
CDS	160..459
Translation	MSSQQSAVSAKGFSKGSSQGPAPCPAPAPTPAPASSSSCCGSGRGCCGDSGCCGSSSTSCCCFPRRRRRQRSSGCCCCGGGSQRSQRSNNRSSGCCSGC

Target ORF information:

RefSeq Version	XM_011509656.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cysteine rich C-terminal 1 (CRCT1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011509656.2

ORF Insert Sequence:

ATGTCCTCTC AACAGAGCGC CGTTTCCGCC AAAGGCTTTT CCAAGGGGTC GTCCCAGGGC 
CCCGCTCCGT GTCCCGCCCC GGCGCCCACC CCGGCGCCCG CCTCCTCCTC CTCCTGCTGC 
GGCTCCGGCA GGGGCTGCTG CGGCGACTCA GGCTGCTGCG GCTCCAGCTC CACCAGTTGC 
TGCTGCTTCC CAAGGAGACG CCGCCGACAG CGGAGTAGTG GTTGCTGCTG CTGCGGGGGC 
GGCAGCCAGA GGTCCCAGCG CTCCAACAAC CGGAGCTCAG GATGCTGCTC CGGCTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

CRCT1 regulated by microRNA-520?g inhibits proliferation and induces apoptosis in esophageal squamous cell cancer.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine37(6)8271-9(2016 Jun)
Wu N,Song Y,Pang L,Chen Z

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
PloS one7(12)e51954(2012)
Comuzzie AG,Cole SA,Laston SL,Voruganti VS,Haack K,Gibbs RA,Butte NF

Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.
Nature genetics43(9)887-92(2011 Jul)
Torgerson DG,Ampleford EJ,Chiu GY,Gauderman WJ,Gignoux CR,Graves PE,Himes BE,Levin AM,Mathias RA,Hancock DB,Baurley JW,Eng C,Stern DA,Celed?n JC,Rafaels N,Capurso D,Conti DV,Roth LA,Soto-Quiros M,Togias A,Li X,Myers RA,Romieu I,Van Den Berg DJ,Hu D,Hansel NN,Hernandez RD,Israel E,Salam MT,Galanter J,Avila PC,Avila L,Rodriquez-Santana JR,Chapela R,Rodriguez-Cintron W,Diette GB,Adkinson NF,Abel RA,Ross KD,Shi M,Faruque MU,Dunston GM,Watson HR,Mantese VJ,Ezurum SC,Liang L,Ruczinski I,Ford JG,Huntsman S,Chung KF,Vora H,Li X,Calhoun WJ,Castro M,Sienra-Monge JJ,del Rio-Navarro B,Deichmann KA,Heinzmann A,Wenzel SE,Busse WW,Gern JE,Lemanske RF Jr,Beaty TH,Bleecker ER,Raby BA,Meyers DA,London SJ,,Gilliland FD,,Burchard EG,,Martinez FD,,Weiss ST,,Williams LK,,Barnes KC,,Ober C,Nicolae DL

A human protein-protein interaction network: a resource for annotating the proteome.
Cell122(6)957-68(2005 Sep)
Stelzl U,Worm U,Lalowski M,Haenig C,Brembeck FH,Goehler H,Stroedicke M,Zenkner M,Schoenherr A,Koeppen S,Timm J,Mintzlaff S,Abraham C,Bock N,Kietzmann S,Goedde A,Toks?z E,Droege A,Krobitsch S,Korn B,Birchmeier W,Lehrach H,Wanker EE

Identification of human epidermal differentiation complex (EDC)-encoded genes by subtractive hybridization of entire YACs to a gridded keratinocyte cDNA library.
Genome research11(3)341-55(2001 Mar)
Marenholz I,Zirra M,Fischer DF,Backendorf C,Ziegler A,Mischke D

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CRCT1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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