Gene Symbol | SLCO1C1 |
Entrez Gene ID | 53919 |
Full Name | solute carrier organic anion transporter family member 1C1 |
Synonyms | OATP-F,OATP1,OATP14,OATP1C1,OATPF,OATPRP5,SLC21A14 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of thyroid hormones in brain tissues. This protein has particularly high affinity for the thyroid hormones thyroxine, tri-iodothyronine and reverse tri-iodothyronine. Polymorphisms in the gene encoding this protein may be associated with fatigue and depression in patients suffering from hyperthyroidism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]. |
Disorder MIM: |