Gene Symbol | PIK3CG |
Entrez Gene ID | 5294 |
Full Name | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma |
Synonyms | PI3CG,PI3K,PI3Kgamma,PIK3,p110gamma,p120-PI3K |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I catalytic subunit of PI3K. Like other class I catalytic subunits (p110-alpha p110-beta, and p110-delta), the encoded protein binds a p85 regulatory subunit to form PI3K. This gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2015]. |
Disorder MIM: |