Gene Symbol | PIK3CD |
Entrez Gene ID | 5293 |
Full Name | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta |
Synonyms | APDS,IMD14,P110DELTA,PI3K,p110D |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I PI3K found primarily in leukocytes. Like other class I PI3Ks (p110-alpha p110-beta, and p110-gamma), the encoded protein binds p85 adapter proteins and GTP-bound RAS. However, unlike the other class I PI3Ks, this protein phosphorylates itself, not p85 protein.[provided by RefSeq, Jul 2010]. |
Disorder MIM: | |
Disorder Html: | Immunodeficiency 14, 615513 (3) |