Gene Symbol | UBE2J1 |
Entrez Gene ID | 51465 |
Full Name | ubiquitin conjugating enzyme E2 J1 |
Synonyms | CGI-76,HSPC153,HSPC205,HSU93243,NCUBE-1,NCUBE1,UBC6,UBC6E,Ubc6p |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum (ER) and may contribute to quality control ER-associated degradation by the ubiquitin-proteasome system. [provided by RefSeq, Jul 2008]. |
Disorder MIM: |