PCSK5 cDNA ORF clone, Homo sapiens(human)

The following PCSK5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PCSK5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu22002 NM_001190482.1
Latest version!
Homo sapiens proprotein convertase subtilisin/kexin type 5 (PCSK5), transcript variant 1, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$659.50-$923.30
$1319.00
OHu22020 NM_006200.6
Latest version!
Homo sapiens proprotein convertase subtilisin/kexin type 5 (PCSK5), transcript variant 2, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$189.50-$265.30
$379.00
OHu98687 XM_017014800.1
Latest version!
Homo sapiens proprotein convertase subtilisin/kexin type 5 (PCSK5), transcript variant X4, mRNA. pcDNA3.1-C-(k)DYK or customized vector 19-21 $727.30
$1039.00
OHu43330 NM_001372043.1
Latest version!
Homo sapiens proprotein convertase subtilisin/kexin type 5 (PCSK5), transcript variant 4, mRNA. pcDNA3.1-C-(k)DYK or customized vector 24-26 $951.30
$1359.00
OHu43330 XM_005252039.4
Latest version!
Homo sapiens proprotein convertase subtilisin/kexin type 5 (PCSK5), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 25 $951.30
$1359.00
OHu59541 XM_011518769.3
Latest version!
Homo sapiens proprotein convertase subtilisin/kexin type 5 (PCSK5), transcript variant X2, mRNA. pcDNA3.1-C-(k)DYK or customized vector 25 $951.30
$1359.00
OHu59542 XM_011518770.2
Latest version!
Homo sapiens proprotein convertase subtilisin/kexin type 5 (PCSK5), transcript variant X3, mRNA. pcDNA3.1-C-(k)DYK or customized vector 25 $727.30
$1039.00
View Old Accession Versions >>
OHu22020 NM_006200.5 Homo sapiens proprotein convertase subtilisin/kexin type 5 (PCSK5), transcript variant 2, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$189.50-$265.30
$379.00
OHu59541 XM_011518769.2 Homo sapiens proprotein convertase subtilisin/kexin type 5 (PCSK5), transcript variant X2, mRNA. pcDNA3.1-C-(k)DYK or customized vector 25 $951.30
$1359.00
OHu43330 XM_005252039.3 Homo sapiens proprotein convertase subtilisin/kexin type 5 (PCSK5), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 25 $951.30
$1359.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

  • Reference Sequences (Refseq)
    CloneID OHu22002
    Clone ID Related Accession (Same CDS sequence) NM_001190482.1
    Accession Version NM_001190482.1 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 5583bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-09-21
    Organism Homo sapiens(human)
    Product proprotein convertase subtilisin/kexin type 5 isoform PC6B preproprotein
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA992221.1, BC012064.1, DV080167.1, DY655633.1, AL589653.9, DT932737.1, AK122718.1 and AL391868.16. This sequence is a reference standard in the RefSeqGene project. Transcript Variant: This variant (1) encodes isoform PC5B, alternatively referred to as the long form. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    4201
    4261
    4321
    4381
    4441
    4501
    4561
    4621
    4681
    4741
    4801
    4861
    4921
    4981
    5041
    5101
    5161
    5221
    5281
    5341
    5401
    5461
    5521
    5581
    ATGGGCTGGG GGAGCCGCTG CTGCTGCCCG GGACGTTTGG ACCTGCTGTG CGTGCTGGCG 
    CTGCTCGGGG GCTGCCTGCT CCCCGTGTGT CGGACGCGCG TCTACACCAA CCACTGGGCA
    GTCAAAATCG CCGGGGGCTT CCCGGAGGCC AACCGTATCG CCAGCAAGTA CGGATTCATC
    AACATAGGAC AGATAGGGGC CCTGAAGGAC TACTACCACT TCTACCATAG CAGGACGATT
    AAAAGGTCAG TTATCTCGAG CAGAGGGACC CACAGTTTCA TTTCAATGGA ACCAAAGGTG
    GAATGGATCC AACAGCAAGT GGTAAAAAAG CGGACAAAGA GGGATTATGA CTTCAGTCGT
    GCCCAGTCTA CCTATTTCAA TGATCCCAAG TGGCCCAGCA TGTGGTATAT GCACTGCAGT
    GACAATACAC ATCCCTGCCA GTCTGACATG AATATCGAAG GAGCCTGGAA GAGAGGCTAC
    ACGGGAAAGA ACATTGTGGT CACTATCCTG GATGACGGAA TTGAGAGAAC CCATCCAGAT
    CTGATGCAAA ACTACGATGC TCTGGCAAGT TGCGACGTGA ATGGGAATGA CTTGGACCCA
    ATGCCTCGTT ATGATGCAAG CAACGAGAAC AAGCATGGGA CTCGCTGTGC TGGAGAAGTG
    GCAGCCGCTG CAAACAATTC GCACTGCACA GTCGGAATTG CTTTCAACGC CAAGATCGGA
    GGAGTGCGAA TGCTGGACGG AGATGTCACG GACATGGTTG AAGCAAAATC AGTTAGCTTC
    AACCCCCAGC ACGTGCACAT TTACAGCGCC AGCTGGGGCC CGGATGATGA TGGCAAGACT
    GTGGACGGAC CAGCCCCCCT CACCCGGCAA GCCTTTGAAA ACGGCGTTAG AATGGGGCGG
    AGAGGCCTCG GCTCTGTGTT TGTTTGGGCA TCTGGAAATG GTGGAAGGAG CAAAGACCAC
    TGCTCCTGTG ATGGCTACAC CAACAGCATC TACACCATCT CCATCAGCAG CACTGCAGAA
    AGCGGAAAGA AACCTTGGTA CCTGGAAGAG TGTTCATCCA CGCTGGCCAC AACCTACAGC
    AGCGGGGAGT CCTACGATAA GAAAATCATC ACTACAGATC TGAGGCAGCG TTGCACGGAC
    AACCACACTG GGACGTCAGC CTCAGCCCCC ATGGCTGCAG GCATCATTGC GCTGGCCCTG
    GAAGCCAATC CGTTTCTGAC CTGGAGAGAC GTACAGCATG TTATTGTCAG GACTTCCCGT
    GCGGGACATT TGAACGCTAA TGACTGGAAA ACCAATGCTG CTGGTTTTAA GGTGAGCCAT
    CTTTATGGAT TTGGACTGAT GGACGCAGAA GCCATGGTGA TGGAGGCAGA GAAGTGGACC
    ACCGTTCCCC GGCAGCACGT GTGTGTGGAG AGCACAGACC GACAAATCAA GACAATCCGC
    CCTAACAGTG CAGTGCGCTC CATCTACAAA GCTTCAGGCT GCTCGGATAA CCCCAACCGC
    CATGTCAACT ACCTGGAGCA CGTCGTTGTG CGCATCACCA TCACCCACCC CAGGAGAGGA
    GACCTGGCCA TCTACCTGAC CTCGCCCTCT GGAACTAGGT CTCAGCTTTT GGCCAACAGG
    CTATTTGATC ACTCCATGGA AGGATTCAAA AACTGGGAGT TCATGACCAT TCATTGCTGG
    GGAGAAAGAG CTGCTGGTGA CTGGGTCCTT GAAGTTTATG ATACTCCCTC TCAGCTAAGG
    AACTTTAAGA CTCCAGGTAA ATTGAAAGAA TGGTCTTTGG TCCTCTACGG CACCTCCGTG
    CAGCCATATT CACCAACCAA TGAATTTCCG AAAGTGGAAC GGTTCCGCTA TAGCCGAGTT
    GAAGACCCCA CAGACGACTA TGGCACAGAG GATTATGCAG GTCCCTGCGA CCCTGAGTGC
    AGTGAGGTTG GCTGTGACGG GCCAGGACCA GACCACTGCA ATGACTGTTT GCACTACTAC
    TACAAGCTGA AAAACAATAC CAGGATCTGT GTCTCCAGCT GCCCCCCTGG CCACTACCAC
    GCCGACAAGA AGCGCTGCAG GAAGTGTGCC CCCAACTGTG AGTCCTGCTT TGGGAGCCAT
    GGTGACCAAT GCATGTCCTG CAAATATGGA TACTTTCTGA ATGAAGAAAC CAACAGCTGT
    GTTACTCACT GCCCTGATGG GTCATATCAG GATACCAAGA AAAATCTTTG CCGGAAATGC
    AGTGAAAACT GCAAGACATG TACTGAATTC CATAACTGTA CAGAATGTAG GGATGGGTTA
    AGCCTGCAGG GATCCCGGTG CTCTGTCTCC TGTGAAGATG GACGGTATTT CAACGGCCAG
    GACTGCCAGC CCTGCCACCG CTTCTGCGCC ACTTGTGCTG GGGCAGGAGC TGATGGGTGC
    ATTAACTGCA CAGAGGGCTA CTTCATGGAG GATGGGAGAT GCGTGCAGAG CTGTAGTATC
    AGCTATTACT TTGACCACTC TTCAGAGAAT GGATACAAAT CCTGCAAAAA ATGTGATATC
    AGTTGTTTGA CGTGCAATGG CCCAGGATTC AAGAACTGTA CAAGCTGCCC TAGTGGGTAT
    CTCTTAGACT TAGGAATGTG TCAAATGGGA GCCATTTGCA AGGATGGAGA ATATGTTGAT
    GAGCATGGCC ACTGCCAGAC CTGTGAGGCC TCATGTGCCA AGTGCCAGGG ACCAACCCAG
    GAAGACTGCA CTACCTGCCC CATGACAAGG ATTTTTGATG ATGGCCGCTG TGTTTCGAAC
    TGCCCCTCAT GGAAATTTGA ATTTGAGAAC CAATGCCATC CATGCCACCA CACCTGCCAG
    AGATGCCAAG GAAGTGGCCC TACCCACTGC ACCTCCTGTG GAGCAGACAA CTATGGCCGA
    GAGCACTTCC TGTACCAGGG AGAGTGTGGA GATAGCTGCC CAGAGGGCCA CTATGCCACT
    GAGGGGAACA CCTGCCTGCC CTGCCCAGAC AACTGTGAGC TTTGCCACAG CGTGCATGTC
    TGCACAAGAT GCATGAAGGG CTACTTCATA GCGCCCACCA ACCACACATG CCAGAAGTTA
    GAGTGTGGAC AAGGTGAAGT CCAAGACCCA GACTATGAAG AATGTGTCCC TTGTGAAGAA
    GGATGTCTGG GATGCAGCTT GGATGATCCA GGAACATGTA CATCTTGCGC TATGGGGTAT
    TACAGGTTTG ATCACCATTG TTATAAAACC TGTCCTGAGA AGACCTACAG TGAGGAAGTG
    GAATGCAAGG CGTGTGATAG TAACTGTGGC AGCTGTGACC AGAATGGGTG TTACTGGTGT
    GAAGAGGGCT TCTTTCTCTT AGGTGGCAGT TGTGTGAGGA AATGTGGTCC TGGATTCTAT
    GGTGACCAAG AAATGGGAGA ATGTGAGTCC TGCCACCGAG CATGCGAAAC CTGCACAGGC
    CCTGGTCATG ACGAGTGCAG CAGCTGCCAG GAAGGACTGC AGCTGCTGCG TGGGATGTGC
    GTGCATGCCA CCAAGACCCA GGAGGAGGGC AAATTCTGGA ATGATATTTT GAGAAAACTC
    CAGCCTTGTC ATTCTTCTTG TAAAACCTGC AATGGATCTG CAACTCTGTG CACTTCATGT
    CCCAAAGGTG CATATCTTCT GGCTCAGGCC TGTGTTTCCT CCTGTCCCCA AGGCACATGG
    CCTTCCGTAA GGAGTGGGAG CTGCGAGAAC TGTACGGAGG CCTGTGCCAT CTGCTCTGGA
    GCCGATCTTT GCAAAAAATG CCAGATGCAG CCGGGCCACC CTCTCTTCCT CCATGAAGGC
    AGGTGCTACT CCAAGTGCCC GGAGGGCTCT TATGCAGAAG ACGGCATATG TGAACGCTGT
    AGCTCTCCTT GCAGAACATG TGAAGGAAAC GCCACCAACT GCCATTCTTG TGAAGGAGGC
    CACGTCCTGC ACCACGGAGT GTGCCAGGAA AACTGCCCCG AGAGGCACGT GGCTGTGAAG
    GGGGTATGCA AGCATTGCCC AGAGATGTGT CAGGACTGCA TCCATGAGAA AACATGCAAA
    GAGTGCACGC CTGAGTTCTT CCTGCACGAT GATATGTGCC ACCAGTCCTG TCCCCGTGGC
    TTCTATGCAG ACTCGCGCCA CTGTGTCCCC TGCCATAAAG ACTGTCTGGA GTGCAGTGGC
    CCCAAAGCCG ACGACTGCGA GCTCTGTCTT GAGAGTTCCT GGGTCCTCTA TGATGGACTG
    TGCTTGGAGG AGTGTCCAGC AGGAACCTAT TATGAAAAGG AGACTAAGGA GTGCAGAGAT
    TGCCACAAGT CCTGCTTGAC CTGCTCATCA TCTGGGACCT GCACCACCTG TCAGAAAGGC
    CTGATCATGA ACCCTCGTGG GAGCTGCATG GCCAACGAGA AGTGCTCACC CTCCGAGTAC
    TGGGATGAGG ATGCTCCCGG GTGCAAGCCC TGCCATGTTA AGTGCTTCCA CTGCATGGGG
    CCGGCGGAGG ACCAGTGTCA AACATGCCCC ATGAACAGCC TTCTTCTCAA CACAACCTGT
    GTGAAGGACT GCCCAGAGGG CTATTATGCC GATGAGGACA GCAACCGGTG TGCCCACTGC
    CACAGCTCTT GCAGGACATG TGAAGGGAGA CACAGCAGGC AGTGCCACTC CTGCCGACCG
    GGCTGGTTCC AGCTAGGAAA AGAGTGCCTG CTCCAGTGCA GGGAAGGATA TTACGCAGAC
    AACTCCACTG GCCGGTGTGA GAGGTGCAAC AGGAGCTGCA AGGGGTGCCA GGGCCCACGG
    CCCACAGACT GCCTGTCTTG CGATAGATTT TTCTTTCTGC TCCGCTCCAA AGGAGAGTGT
    CATCGCTCCT GCCCAGACCA TTACTATGTA GAGCAAAGCA CACAGACCTG TGAGAGATGC
    CATCCGACTT GTGATCAATG CAAAGGAAAA GGAGCGTTGA ATTGTTTATC CTGTGTGTGG
    AGTTACCACC TCATGGGAGG GATCTGCACC TCGGACTGTC TTGTGGGGGA ATACAGAGTG
    GGAGAGGGAG AGAAGTTTAA CTGTGAAAAA TGCCACGAGA GCTGCATGGA ATGCAAGGGA
    CCAGGGGCCA AGAACTGCAC CTTGTGCCCT GCCAACCTGG TGCTGCACAT GGACGACAGC
    CACTGCCTCC ACTGCTGCAA CACCTCTGAT CCCCCCAGTG CCCAGGAGTG CTGTGACTGC
    CAGGACACCA CGGACGAATG CATCCTTCGA ACAAGCAAGG TTAGGCCTGC AACTGAGCAT
    TTCAAGACAG CTCTGTTCAT CACCTCCTCC ATGATGCTGG TGCTTCTGCT CGGGGCAGCT
    GTGGTAGTGT GGAAGAAATC TCGTGGCCGA GTCCAGCCAG CAGCAAAGGC CGGCTATGAA
    AAACTGGCCG ACCCCAACAA GTCTTACTCC TCCTATAAGA GCAGCTATAG AGAGAGCACC
    AGCTTTGAAG AGGATCAGGT GATTGAGTAC AGGGATCGGG ACTATGATGA GGATGATGAT
    GATGACATCG TCTACATGGG CCAGGATGGC ACAGTCTACC GGAAATTTAA ATATGGGCTG
    CTGGATGACG ATGACATAGA TGAGCTGGAA TATGATGACG AGAGTTACTC CTACTACCAG
    TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001177411.1
    CDS539..6121
    Translation

    Target ORF information:

    RefSeq Version NM_001190482.1
    Organism Homo sapiens(human)
    Definition Homo sapiens proprotein convertase subtilisin/kexin type 5 (PCSK5), transcript variant 1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001190482.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    4201
    4261
    4321
    4381
    4441
    4501
    4561
    4621
    4681
    4741
    4801
    4861
    4921
    4981
    5041
    5101
    5161
    5221
    5281
    5341
    5401
    5461
    5521
    5581
    ATGGGCTGGG GGAGCCGCTG CTGCTGCCCG GGACGTTTGG ACCTGCTGTG CGTGCTGGCG 
    CTGCTCGGGG GCTGCCTGCT CCCCGTGTGT CGGACGCGCG TCTACACCAA CCACTGGGCA
    GTCAAAATCG CCGGGGGCTT CCCGGAGGCC AACCGTATCG CCAGCAAGTA CGGATTCATC
    AACATAGGAC AGATAGGGGC CCTGAAGGAC TACTACCACT TCTACCATAG CAGGACGATT
    AAAAGGTCAG TTATCTCGAG CAGAGGGACC CACAGTTTCA TTTCAATGGA ACCAAAGGTG
    GAATGGATCC AACAGCAAGT GGTAAAAAAG CGGACAAAGA GGGATTATGA CTTCAGTCGT
    GCCCAGTCTA CCTATTTCAA TGATCCCAAG TGGCCCAGCA TGTGGTATAT GCACTGCAGT
    GACAATACAC ATCCCTGCCA GTCTGACATG AATATCGAAG GAGCCTGGAA GAGAGGCTAC
    ACGGGAAAGA ACATTGTGGT CACTATCCTG GATGACGGAA TTGAGAGAAC CCATCCAGAT
    CTGATGCAAA ACTACGATGC TCTGGCAAGT TGCGACGTGA ATGGGAATGA CTTGGACCCA
    ATGCCTCGTT ATGATGCAAG CAACGAGAAC AAGCATGGGA CTCGCTGTGC TGGAGAAGTG
    GCAGCCGCTG CAAACAATTC GCACTGCACA GTCGGAATTG CTTTCAACGC CAAGATCGGA
    GGAGTGCGAA TGCTGGACGG AGATGTCACG GACATGGTTG AAGCAAAATC AGTTAGCTTC
    AACCCCCAGC ACGTGCACAT TTACAGCGCC AGCTGGGGCC CGGATGATGA TGGCAAGACT
    GTGGACGGAC CAGCCCCCCT CACCCGGCAA GCCTTTGAAA ACGGCGTTAG AATGGGGCGG
    AGAGGCCTCG GCTCTGTGTT TGTTTGGGCA TCTGGAAATG GTGGAAGGAG CAAAGACCAC
    TGCTCCTGTG ATGGCTACAC CAACAGCATC TACACCATCT CCATCAGCAG CACTGCAGAA
    AGCGGAAAGA AACCTTGGTA CCTGGAAGAG TGTTCATCCA CGCTGGCCAC AACCTACAGC
    AGCGGGGAGT CCTACGATAA GAAAATCATC ACTACAGATC TGAGGCAGCG TTGCACGGAC
    AACCACACTG GGACGTCAGC CTCAGCCCCC ATGGCTGCAG GCATCATTGC GCTGGCCCTG
    GAAGCCAATC CGTTTCTGAC CTGGAGAGAC GTACAGCATG TTATTGTCAG GACTTCCCGT
    GCGGGACATT TGAACGCTAA TGACTGGAAA ACCAATGCTG CTGGTTTTAA GGTGAGCCAT
    CTTTATGGAT TTGGACTGAT GGACGCAGAA GCCATGGTGA TGGAGGCAGA GAAGTGGACC
    ACCGTTCCCC GGCAGCACGT GTGTGTGGAG AGCACAGACC GACAAATCAA GACAATCCGC
    CCTAACAGTG CAGTGCGCTC CATCTACAAA GCTTCAGGCT GCTCGGATAA CCCCAACCGC
    CATGTCAACT ACCTGGAGCA CGTCGTTGTG CGCATCACCA TCACCCACCC CAGGAGAGGA
    GACCTGGCCA TCTACCTGAC CTCGCCCTCT GGAACTAGGT CTCAGCTTTT GGCCAACAGG
    CTATTTGATC ACTCCATGGA AGGATTCAAA AACTGGGAGT TCATGACCAT TCATTGCTGG
    GGAGAAAGAG CTGCTGGTGA CTGGGTCCTT GAAGTTTATG ATACTCCCTC TCAGCTAAGG
    AACTTTAAGA CTCCAGGTAA ATTGAAAGAA TGGTCTTTGG TCCTCTACGG CACCTCCGTG
    CAGCCATATT CACCAACCAA TGAATTTCCG AAAGTGGAAC GGTTCCGCTA TAGCCGAGTT
    GAAGACCCCA CAGACGACTA TGGCACAGAG GATTATGCAG GTCCCTGCGA CCCTGAGTGC
    AGTGAGGTTG GCTGTGACGG GCCAGGACCA GACCACTGCA ATGACTGTTT GCACTACTAC
    TACAAGCTGA AAAACAATAC CAGGATCTGT GTCTCCAGCT GCCCCCCTGG CCACTACCAC
    GCCGACAAGA AGCGCTGCAG GAAGTGTGCC CCCAACTGTG AGTCCTGCTT TGGGAGCCAT
    GGTGACCAAT GCATGTCCTG CAAATATGGA TACTTTCTGA ATGAAGAAAC CAACAGCTGT
    GTTACTCACT GCCCTGATGG GTCATATCAG GATACCAAGA AAAATCTTTG CCGGAAATGC
    AGTGAAAACT GCAAGACATG TACTGAATTC CATAACTGTA CAGAATGTAG GGATGGGTTA
    AGCCTGCAGG GATCCCGGTG CTCTGTCTCC TGTGAAGATG GACGGTATTT CAACGGCCAG
    GACTGCCAGC CCTGCCACCG CTTCTGCGCC ACTTGTGCTG GGGCAGGAGC TGATGGGTGC
    ATTAACTGCA CAGAGGGCTA CTTCATGGAG GATGGGAGAT GCGTGCAGAG CTGTAGTATC
    AGCTATTACT TTGACCACTC TTCAGAGAAT GGATACAAAT CCTGCAAAAA ATGTGATATC
    AGTTGTTTGA CGTGCAATGG CCCAGGATTC AAGAACTGTA CAAGCTGCCC TAGTGGGTAT
    CTCTTAGACT TAGGAATGTG TCAAATGGGA GCCATTTGCA AGGATGGAGA ATATGTTGAT
    GAGCATGGCC ACTGCCAGAC CTGTGAGGCC TCATGTGCCA AGTGCCAGGG ACCAACCCAG
    GAAGACTGCA CTACCTGCCC CATGACAAGG ATTTTTGATG ATGGCCGCTG TGTTTCGAAC
    TGCCCCTCAT GGAAATTTGA ATTTGAGAAC CAATGCCATC CATGCCACCA CACCTGCCAG
    AGATGCCAAG GAAGTGGCCC TACCCACTGC ACCTCCTGTG GAGCAGACAA CTATGGCCGA
    GAGCACTTCC TGTACCAGGG AGAGTGTGGA GATAGCTGCC CAGAGGGCCA CTATGCCACT
    GAGGGGAACA CCTGCCTGCC CTGCCCAGAC AACTGTGAGC TTTGCCACAG CGTGCATGTC
    TGCACAAGAT GCATGAAGGG CTACTTCATA GCGCCCACCA ACCACACATG CCAGAAGTTA
    GAGTGTGGAC AAGGTGAAGT CCAAGACCCA GACTATGAAG AATGTGTCCC TTGTGAAGAA
    GGATGTCTGG GATGCAGCTT GGATGATCCA GGAACATGTA CATCTTGCGC TATGGGGTAT
    TACAGGTTTG ATCACCATTG TTATAAAACC TGTCCTGAGA AGACCTACAG TGAGGAAGTG
    GAATGCAAGG CGTGTGATAG TAACTGTGGC AGCTGTGACC AGAATGGGTG TTACTGGTGT
    GAAGAGGGCT TCTTTCTCTT AGGTGGCAGT TGTGTGAGGA AATGTGGTCC TGGATTCTAT
    GGTGACCAAG AAATGGGAGA ATGTGAGTCC TGCCACCGAG CATGCGAAAC CTGCACAGGC
    CCTGGTCATG ACGAGTGCAG CAGCTGCCAG GAAGGACTGC AGCTGCTGCG TGGGATGTGC
    GTGCATGCCA CCAAGACCCA GGAGGAGGGC AAATTCTGGA ATGATATTTT GAGAAAACTC
    CAGCCTTGTC ATTCTTCTTG TAAAACCTGC AATGGATCTG CAACTCTGTG CACTTCATGT
    CCCAAAGGTG CATATCTTCT GGCTCAGGCC TGTGTTTCCT CCTGTCCCCA AGGCACATGG
    CCTTCCGTAA GGAGTGGGAG CTGCGAGAAC TGTACGGAGG CCTGTGCCAT CTGCTCTGGA
    GCCGATCTTT GCAAAAAATG CCAGATGCAG CCGGGCCACC CTCTCTTCCT CCATGAAGGC
    AGGTGCTACT CCAAGTGCCC GGAGGGCTCT TATGCAGAAG ACGGCATATG TGAACGCTGT
    AGCTCTCCTT GCAGAACATG TGAAGGAAAC GCCACCAACT GCCATTCTTG TGAAGGAGGC
    CACGTCCTGC ACCACGGAGT GTGCCAGGAA AACTGCCCCG AGAGGCACGT GGCTGTGAAG
    GGGGTATGCA AGCATTGCCC AGAGATGTGT CAGGACTGCA TCCATGAGAA AACATGCAAA
    GAGTGCACGC CTGAGTTCTT CCTGCACGAT GATATGTGCC ACCAGTCCTG TCCCCGTGGC
    TTCTATGCAG ACTCGCGCCA CTGTGTCCCC TGCCATAAAG ACTGTCTGGA GTGCAGTGGC
    CCCAAAGCCG ACGACTGCGA GCTCTGTCTT GAGAGTTCCT GGGTCCTCTA TGATGGACTG
    TGCTTGGAGG AGTGTCCAGC AGGAACCTAT TATGAAAAGG AGACTAAGGA GTGCAGAGAT
    TGCCACAAGT CCTGCTTGAC CTGCTCATCA TCTGGGACCT GCACCACCTG TCAGAAAGGC
    CTGATCATGA ACCCTCGTGG GAGCTGCATG GCCAACGAGA AGTGCTCACC CTCCGAGTAC
    TGGGATGAGG ATGCTCCCGG GTGCAAGCCC TGCCATGTTA AGTGCTTCCA CTGCATGGGG
    CCGGCGGAGG ACCAGTGTCA AACATGCCCC ATGAACAGCC TTCTTCTCAA CACAACCTGT
    GTGAAGGACT GCCCAGAGGG CTATTATGCC GATGAGGACA GCAACCGGTG TGCCCACTGC
    CACAGCTCTT GCAGGACATG TGAAGGGAGA CACAGCAGGC AGTGCCACTC CTGCCGACCG
    GGCTGGTTCC AGCTAGGAAA AGAGTGCCTG CTCCAGTGCA GGGAAGGATA TTACGCAGAC
    AACTCCACTG GCCGGTGTGA GAGGTGCAAC AGGAGCTGCA AGGGGTGCCA GGGCCCACGG
    CCCACAGACT GCCTGTCTTG CGATAGATTT TTCTTTCTGC TCCGCTCCAA AGGAGAGTGT
    CATCGCTCCT GCCCAGACCA TTACTATGTA GAGCAAAGCA CACAGACCTG TGAGAGATGC
    CATCCGACTT GTGATCAATG CAAAGGAAAA GGAGCGTTGA ATTGTTTATC CTGTGTGTGG
    AGTTACCACC TCATGGGAGG GATCTGCACC TCGGACTGTC TTGTGGGGGA ATACAGAGTG
    GGAGAGGGAG AGAAGTTTAA CTGTGAAAAA TGCCACGAGA GCTGCATGGA ATGCAAGGGA
    CCAGGGGCCA AGAACTGCAC CTTGTGCCCT GCCAACCTGG TGCTGCACAT GGACGACAGC
    CACTGCCTCC ACTGCTGCAA CACCTCTGAT CCCCCCAGTG CCCAGGAGTG CTGTGACTGC
    CAGGACACCA CGGACGAATG CATCCTTCGA ACAAGCAAGG TTAGGCCTGC AACTGAGCAT
    TTCAAGACAG CTCTGTTCAT CACCTCCTCC ATGATGCTGG TGCTTCTGCT CGGGGCAGCT
    GTGGTAGTGT GGAAGAAATC TCGTGGCCGA GTCCAGCCAG CAGCAAAGGC CGGCTATGAA
    AAACTGGCCG ACCCCAACAA GTCTTACTCC TCCTATAAGA GCAGCTATAG AGAGAGCACC
    AGCTTTGAAG AGGATCAGGT GATTGAGTAC AGGGATCGGG ACTATGATGA GGATGATGAT
    GATGACATCG TCTACATGGG CCAGGATGGC ACAGTCTACC GGAAATTTAA ATATGGGCTG
    CTGGATGACG ATGACATAGA TGAGCTGGAA TATGATGACG AGAGTTACTC CTACTACCAG
    TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu22020
    Clone ID Related Accession (Same CDS sequence) NM_006200.6 , NM_006200.5
    Accession Version NM_006200.6 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 2742bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-09-28
    Organism Homo sapiens(human)
    Product proprotein convertase subtilisin/kexin type 5 isoform PC6A preproprotein
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA992221.1, BC012064.1, HY155058.1, AK023096.1, CK023649.1, CN360310.1, AI379031.1 and BM719207.1. On Jun 2, 2019 this sequence version replaced NM_006200.5. Transcript Variant: This variant (2) lacks several 3' exons but contains an alternate 3' terminal exon, and it thus differs in the 3' coding region and 3' UTR, compared to variant 1. The resulting isoform (PC5A, alternatively referred to as the short form) has a substantially shorter and distinct C-terminus, compared to isoform PC5B. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.31137.1, BC012064.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    ATGGGCTGGG GGAGCCGCTG CTGCTGCCCG GGACGTTTGG ACCTGCTGTG CGTGCTGGCG 
    CTGCTCGGGG GCTGCCTGCT CCCCGTGTGT CGGACGCGCG TCTACACCAA CCACTGGGCA
    GTCAAAATCG CCGGGGGCTT CCCGGAGGCC AACCGTATCG CCAGCAAGTA CGGATTCATC
    AACATAGGAC AGATAGGGGC CCTGAAGGAC TACTACCACT TCTACCATAG CAGGACGATT
    AAAAGGTCAG TTATCTCGAG CAGAGGGACC CACAGTTTCA TTTCAATGGA ACCAAAGGTG
    GAATGGATCC AACAGCAAGT GGTAAAAAAG CGGACAAAGA GGGATTATGA CTTCAGTCGT
    GCCCAGTCTA CCTATTTCAA TGATCCCAAG TGGCCCAGCA TGTGGTATAT GCACTGCAGT
    GACAATACAC ATCCCTGCCA GTCTGACATG AATATCGAAG GAGCCTGGAA GAGAGGCTAC
    ACGGGAAAGA ACATTGTGGT CACTATCCTG GATGACGGAA TTGAGAGAAC CCATCCAGAT
    CTGATGCAAA ACTACGATGC TCTGGCAAGT TGCGACGTGA ATGGGAATGA CTTGGACCCA
    ATGCCTCGTT ATGATGCAAG CAACGAGAAC AAGCATGGGA CTCGCTGTGC TGGAGAAGTG
    GCAGCCGCTG CAAACAATTC GCACTGCACA GTCGGAATTG CTTTCAACGC CAAGATCGGA
    GGAGTGCGAA TGCTGGACGG AGATGTCACG GACATGGTTG AAGCAAAATC AGTTAGCTTC
    AACCCCCAGC ACGTGCACAT TTACAGCGCC AGCTGGGGCC CGGATGATGA TGGCAAGACT
    GTGGACGGAC CAGCCCCCCT CACCCGGCAA GCCTTTGAAA ACGGCGTTAG AATGGGGCGG
    AGAGGCCTCG GCTCTGTGTT TGTTTGGGCA TCTGGAAATG GTGGAAGGAG CAAAGACCAC
    TGCTCCTGTG ATGGCTACAC CAACAGCATC TACACCATCT CCATCAGCAG CACTGCAGAA
    AGCGGAAAGA AACCTTGGTA CCTGGAAGAG TGTTCATCCA CGCTGGCCAC AACCTACAGC
    AGCGGGGAGT CCTACGATAA GAAAATCATC ACTACAGATC TGAGGCAGCG TTGCACGGAC
    AACCACACTG GGACGTCAGC CTCAGCCCCC ATGGCTGCAG GCATCATTGC GCTGGCCCTG
    GAAGCCAATC CGTTTCTGAC CTGGAGAGAC GTACAGCATG TTATTGTCAG GACTTCCCGT
    GCGGGACATT TGAACGCTAA TGACTGGAAA ACCAATGCTG CTGGTTTTAA GGTGAGCCAT
    CTTTATGGAT TTGGACTGAT GGACGCAGAA GCCATGGTGA TGGAGGCAGA GAAGTGGACC
    ACCGTTCCCC GGCAGCACGT GTGTGTGGAG AGCACAGACC GACAAATCAA GACAATCCGC
    CCTAACAGTG CAGTGCGCTC CATCTACAAA GCTTCAGGCT GCTCGGATAA CCCCAACCGC
    CATGTCAACT ACCTGGAGCA CGTCGTTGTG CGCATCACCA TCACCCACCC CAGGAGAGGA
    GACCTGGCCA TCTACCTGAC CTCGCCCTCT GGAACTAGGT CTCAGCTTTT GGCCAACAGG
    CTATTTGATC ACTCCATGGA AGGATTCAAA AACTGGGAGT TCATGACCAT TCATTGCTGG
    GGAGAAAGAG CTGCTGGTGA CTGGGTCCTT GAAGTTTATG ATACTCCCTC TCAGCTAAGG
    AACTTTAAGA CTCCAGGTAA ATTGAAAGAA TGGTCTTTGG TCCTCTACGG CACCTCCGTG
    CAGCCATATT CACCAACCAA TGAATTTCCG AAAGTGGAAC GGTTCCGCTA TAGCCGAGTT
    GAAGACCCCA CAGACGACTA TGGCACAGAG GATTATGCAG GTCCCTGCGA CCCTGAGTGC
    AGTGAGGTTG GCTGTGACGG GCCAGGACCA GACCACTGCA ATGACTGTTT GCACTACTAC
    TACAAGCTGA AAAACAATAC CAGGATCTGT GTCTCCAGCT GCCCCCCTGG CCACTACCAC
    GCCGACAAGA AGCGCTGCAG GAAGTGTGCC CCCAACTGTG AGTCCTGCTT TGGGAGCCAT
    GGTGACCAAT GCATGTCCTG CAAATATGGA TACTTTCTGA ATGAAGAAAC CAACAGCTGT
    GTTACTCACT GCCCTGATGG GTCATATCAG GATACCAAGA AAAATCTTTG CCGGAAATGC
    AGTGAAAACT GCAAGACATG TACTGAATTC CATAACTGTA CAGAATGTAG GGATGGGTTA
    AGCCTGCAGG GATCCCGGTG CTCTGTCTCC TGTGAAGATG GACGGTATTT CAACGGCCAG
    GACTGCCAGC CCTGCCACCG CTTCTGCGCC ACTTGTGCTG GGGCAGGAGC TGATGGGTGC
    ATTAACTGCA CAGAGGGCTA CTTCATGGAG GATGGGAGAT GCGTGCAGAG CTGTAGTATC
    AGCTATTACT TTGACCACTC TTCAGAGAAT GGATACAAAT CCTGCAAAAA ATGTGATATC
    AGTTGTTTGA CGTGCAATGG CCCAGGATTC AAGAACTGTA CAAGCTGCCC TAGTGGGTAT
    CTCTTAGACT TAGGAATGTG TCAAATGGGA GCCATTTGCA AGGATGCAAC GGAAGAGTCC
    TGGGCGGAAG GAGGCTTCTG TATGCTTGTG AAAAAGAACA ATCTGTGCCA ACGGAAGGTT
    CTTCAACAAC TTTGCTGCAA AACATGTACA TTTCAAGGCT GA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_006191.2
    CDS510..3251
    Translation

    Target ORF information:

    RefSeq Version NM_006200.6
    Organism Homo sapiens(human)
    Definition Homo sapiens proprotein convertase subtilisin/kexin type 5 (PCSK5), transcript variant 2, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_006200.6

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    ATGGGCTGGG GGAGCCGCTG CTGCTGCCCG GGACGTTTGG ACCTGCTGTG CGTGCTGGCG 
    CTGCTCGGGG GCTGCCTGCT CCCCGTGTGT CGGACGCGCG TCTACACCAA CCACTGGGCA
    GTCAAAATCG CCGGGGGCTT CCCGGAGGCC AACCGTATCG CCAGCAAGTA CGGATTCATC
    AACATAGGAC AGATAGGGGC CCTGAAGGAC TACTACCACT TCTACCATAG CAGGACGATT
    AAAAGGTCAG TTATCTCGAG CAGAGGGACC CACAGTTTCA TTTCAATGGA ACCAAAGGTG
    GAATGGATCC AACAGCAAGT GGTAAAAAAG CGGACAAAGA GGGATTATGA CTTCAGTCGT
    GCCCAGTCTA CCTATTTCAA TGATCCCAAG TGGCCCAGCA TGTGGTATAT GCACTGCAGT
    GACAATACAC ATCCCTGCCA GTCTGACATG AATATCGAAG GAGCCTGGAA GAGAGGCTAC
    ACGGGAAAGA ACATTGTGGT CACTATCCTG GATGACGGAA TTGAGAGAAC CCATCCAGAT
    CTGATGCAAA ACTACGATGC TCTGGCAAGT TGCGACGTGA ATGGGAATGA CTTGGACCCA
    ATGCCTCGTT ATGATGCAAG CAACGAGAAC AAGCATGGGA CTCGCTGTGC TGGAGAAGTG
    GCAGCCGCTG CAAACAATTC GCACTGCACA GTCGGAATTG CTTTCAACGC CAAGATCGGA
    GGAGTGCGAA TGCTGGACGG AGATGTCACG GACATGGTTG AAGCAAAATC AGTTAGCTTC
    AACCCCCAGC ACGTGCACAT TTACAGCGCC AGCTGGGGCC CGGATGATGA TGGCAAGACT
    GTGGACGGAC CAGCCCCCCT CACCCGGCAA GCCTTTGAAA ACGGCGTTAG AATGGGGCGG
    AGAGGCCTCG GCTCTGTGTT TGTTTGGGCA TCTGGAAATG GTGGAAGGAG CAAAGACCAC
    TGCTCCTGTG ATGGCTACAC CAACAGCATC TACACCATCT CCATCAGCAG CACTGCAGAA
    AGCGGAAAGA AACCTTGGTA CCTGGAAGAG TGTTCATCCA CGCTGGCCAC AACCTACAGC
    AGCGGGGAGT CCTACGATAA GAAAATCATC ACTACAGATC TGAGGCAGCG TTGCACGGAC
    AACCACACTG GGACGTCAGC CTCAGCCCCC ATGGCTGCAG GCATCATTGC GCTGGCCCTG
    GAAGCCAATC CGTTTCTGAC CTGGAGAGAC GTACAGCATG TTATTGTCAG GACTTCCCGT
    GCGGGACATT TGAACGCTAA TGACTGGAAA ACCAATGCTG CTGGTTTTAA GGTGAGCCAT
    CTTTATGGAT TTGGACTGAT GGACGCAGAA GCCATGGTGA TGGAGGCAGA GAAGTGGACC
    ACCGTTCCCC GGCAGCACGT GTGTGTGGAG AGCACAGACC GACAAATCAA GACAATCCGC
    CCTAACAGTG CAGTGCGCTC CATCTACAAA GCTTCAGGCT GCTCGGATAA CCCCAACCGC
    CATGTCAACT ACCTGGAGCA CGTCGTTGTG CGCATCACCA TCACCCACCC CAGGAGAGGA
    GACCTGGCCA TCTACCTGAC CTCGCCCTCT GGAACTAGGT CTCAGCTTTT GGCCAACAGG
    CTATTTGATC ACTCCATGGA AGGATTCAAA AACTGGGAGT TCATGACCAT TCATTGCTGG
    GGAGAAAGAG CTGCTGGTGA CTGGGTCCTT GAAGTTTATG ATACTCCCTC TCAGCTAAGG
    AACTTTAAGA CTCCAGGTAA ATTGAAAGAA TGGTCTTTGG TCCTCTACGG CACCTCCGTG
    CAGCCATATT CACCAACCAA TGAATTTCCG AAAGTGGAAC GGTTCCGCTA TAGCCGAGTT
    GAAGACCCCA CAGACGACTA TGGCACAGAG GATTATGCAG GTCCCTGCGA CCCTGAGTGC
    AGTGAGGTTG GCTGTGACGG GCCAGGACCA GACCACTGCA ATGACTGTTT GCACTACTAC
    TACAAGCTGA AAAACAATAC CAGGATCTGT GTCTCCAGCT GCCCCCCTGG CCACTACCAC
    GCCGACAAGA AGCGCTGCAG GAAGTGTGCC CCCAACTGTG AGTCCTGCTT TGGGAGCCAT
    GGTGACCAAT GCATGTCCTG CAAATATGGA TACTTTCTGA ATGAAGAAAC CAACAGCTGT
    GTTACTCACT GCCCTGATGG GTCATATCAG GATACCAAGA AAAATCTTTG CCGGAAATGC
    AGTGAAAACT GCAAGACATG TACTGAATTC CATAACTGTA CAGAATGTAG GGATGGGTTA
    AGCCTGCAGG GATCCCGGTG CTCTGTCTCC TGTGAAGATG GACGGTATTT CAACGGCCAG
    GACTGCCAGC CCTGCCACCG CTTCTGCGCC ACTTGTGCTG GGGCAGGAGC TGATGGGTGC
    ATTAACTGCA CAGAGGGCTA CTTCATGGAG GATGGGAGAT GCGTGCAGAG CTGTAGTATC
    AGCTATTACT TTGACCACTC TTCAGAGAAT GGATACAAAT CCTGCAAAAA ATGTGATATC
    AGTTGTTTGA CGTGCAATGG CCCAGGATTC AAGAACTGTA CAAGCTGCCC TAGTGGGTAT
    CTCTTAGACT TAGGAATGTG TCAAATGGGA GCCATTTGCA AGGATGCAAC GGAAGAGTCC
    TGGGCGGAAG GAGGCTTCTG TATGCTTGTG AAAAAGAACA ATCTGTGCCA ACGGAAGGTT
    CTTCAACAAC TTTGCTGCAA AACATGTACA TTTCAAGGCT GA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu22020
    Clone ID Related Accession (Same CDS sequence) NM_006200.6 , NM_006200.5
    Accession Version NM_006200.5 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 2742bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-02-23
    Organism Homo sapiens(human)
    Product proprotein convertase subtilisin/kexin type 5 isoform PC6A preproprotein
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA992221.1, BC012064.1, HY155058.1, AK023096.1, CK023649.1, CN360310.1, AI379031.1 and BM719207.1. On May 10, 2014 this sequence version replaced NM_006200.4. Transcript Variant: This variant (2) lacks several 3' exons but contains an alternate 3' terminal exon, and it thus differs in the 3' coding region and 3' UTR, compared to variant 1. The resulting isoform (PC5A, alternatively referred to as the short form) has a substantially shorter and distinct C-terminus, compared to isoform PC5B. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.31137.1, BC012064.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    ATGGGCTGGG GGAGCCGCTG CTGCTGCCCG GGACGTTTGG ACCTGCTGTG CGTGCTGGCG 
    CTGCTCGGGG GCTGCCTGCT CCCCGTGTGT CGGACGCGCG TCTACACCAA CCACTGGGCA
    GTCAAAATCG CCGGGGGCTT CCCGGAGGCC AACCGTATCG CCAGCAAGTA CGGATTCATC
    AACATAGGAC AGATAGGGGC CCTGAAGGAC TACTACCACT TCTACCATAG CAGGACGATT
    AAAAGGTCAG TTATCTCGAG CAGAGGGACC CACAGTTTCA TTTCAATGGA ACCAAAGGTG
    GAATGGATCC AACAGCAAGT GGTAAAAAAG CGGACAAAGA GGGATTATGA CTTCAGTCGT
    GCCCAGTCTA CCTATTTCAA TGATCCCAAG TGGCCCAGCA TGTGGTATAT GCACTGCAGT
    GACAATACAC ATCCCTGCCA GTCTGACATG AATATCGAAG GAGCCTGGAA GAGAGGCTAC
    ACGGGAAAGA ACATTGTGGT CACTATCCTG GATGACGGAA TTGAGAGAAC CCATCCAGAT
    CTGATGCAAA ACTACGATGC TCTGGCAAGT TGCGACGTGA ATGGGAATGA CTTGGACCCA
    ATGCCTCGTT ATGATGCAAG CAACGAGAAC AAGCATGGGA CTCGCTGTGC TGGAGAAGTG
    GCAGCCGCTG CAAACAATTC GCACTGCACA GTCGGAATTG CTTTCAACGC CAAGATCGGA
    GGAGTGCGAA TGCTGGACGG AGATGTCACG GACATGGTTG AAGCAAAATC AGTTAGCTTC
    AACCCCCAGC ACGTGCACAT TTACAGCGCC AGCTGGGGCC CGGATGATGA TGGCAAGACT
    GTGGACGGAC CAGCCCCCCT CACCCGGCAA GCCTTTGAAA ACGGCGTTAG AATGGGGCGG
    AGAGGCCTCG GCTCTGTGTT TGTTTGGGCA TCTGGAAATG GTGGAAGGAG CAAAGACCAC
    TGCTCCTGTG ATGGCTACAC CAACAGCATC TACACCATCT CCATCAGCAG CACTGCAGAA
    AGCGGAAAGA AACCTTGGTA CCTGGAAGAG TGTTCATCCA CGCTGGCCAC AACCTACAGC
    AGCGGGGAGT CCTACGATAA GAAAATCATC ACTACAGATC TGAGGCAGCG TTGCACGGAC
    AACCACACTG GGACGTCAGC CTCAGCCCCC ATGGCTGCAG GCATCATTGC GCTGGCCCTG
    GAAGCCAATC CGTTTCTGAC CTGGAGAGAC GTACAGCATG TTATTGTCAG GACTTCCCGT
    GCGGGACATT TGAACGCTAA TGACTGGAAA ACCAATGCTG CTGGTTTTAA GGTGAGCCAT
    CTTTATGGAT TTGGACTGAT GGACGCAGAA GCCATGGTGA TGGAGGCAGA GAAGTGGACC
    ACCGTTCCCC GGCAGCACGT GTGTGTGGAG AGCACAGACC GACAAATCAA GACAATCCGC
    CCTAACAGTG CAGTGCGCTC CATCTACAAA GCTTCAGGCT GCTCGGATAA CCCCAACCGC
    CATGTCAACT ACCTGGAGCA CGTCGTTGTG CGCATCACCA TCACCCACCC CAGGAGAGGA
    GACCTGGCCA TCTACCTGAC CTCGCCCTCT GGAACTAGGT CTCAGCTTTT GGCCAACAGG
    CTATTTGATC ACTCCATGGA AGGATTCAAA AACTGGGAGT TCATGACCAT TCATTGCTGG
    GGAGAAAGAG CTGCTGGTGA CTGGGTCCTT GAAGTTTATG ATACTCCCTC TCAGCTAAGG
    AACTTTAAGA CTCCAGGTAA ATTGAAAGAA TGGTCTTTGG TCCTCTACGG CACCTCCGTG
    CAGCCATATT CACCAACCAA TGAATTTCCG AAAGTGGAAC GGTTCCGCTA TAGCCGAGTT
    GAAGACCCCA CAGACGACTA TGGCACAGAG GATTATGCAG GTCCCTGCGA CCCTGAGTGC
    AGTGAGGTTG GCTGTGACGG GCCAGGACCA GACCACTGCA ATGACTGTTT GCACTACTAC
    TACAAGCTGA AAAACAATAC CAGGATCTGT GTCTCCAGCT GCCCCCCTGG CCACTACCAC
    GCCGACAAGA AGCGCTGCAG GAAGTGTGCC CCCAACTGTG AGTCCTGCTT TGGGAGCCAT
    GGTGACCAAT GCATGTCCTG CAAATATGGA TACTTTCTGA ATGAAGAAAC CAACAGCTGT
    GTTACTCACT GCCCTGATGG GTCATATCAG GATACCAAGA AAAATCTTTG CCGGAAATGC
    AGTGAAAACT GCAAGACATG TACTGAATTC CATAACTGTA CAGAATGTAG GGATGGGTTA
    AGCCTGCAGG GATCCCGGTG CTCTGTCTCC TGTGAAGATG GACGGTATTT CAACGGCCAG
    GACTGCCAGC CCTGCCACCG CTTCTGCGCC ACTTGTGCTG GGGCAGGAGC TGATGGGTGC
    ATTAACTGCA CAGAGGGCTA CTTCATGGAG GATGGGAGAT GCGTGCAGAG CTGTAGTATC
    AGCTATTACT TTGACCACTC TTCAGAGAAT GGATACAAAT CCTGCAAAAA ATGTGATATC
    AGTTGTTTGA CGTGCAATGG CCCAGGATTC AAGAACTGTA CAAGCTGCCC TAGTGGGTAT
    CTCTTAGACT TAGGAATGTG TCAAATGGGA GCCATTTGCA AGGATGCAAC GGAAGAGTCC
    TGGGCGGAAG GAGGCTTCTG TATGCTTGTG AAAAAGAACA ATCTGTGCCA ACGGAAGGTT
    CTTCAACAAC TTTGCTGCAA AACATGTACA TTTCAAGGCT GA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_006191.2
    CDS539..3280
    Translation

    Target ORF information:

    RefSeq Version NM_006200.5
    Organism Homo sapiens(human)
    Definition Homo sapiens proprotein convertase subtilisin/kexin type 5 (PCSK5), transcript variant 2, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_006200.5

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    ATGGGCTGGG GGAGCCGCTG CTGCTGCCCG GGACGTTTGG ACCTGCTGTG CGTGCTGGCG 
    CTGCTCGGGG GCTGCCTGCT CCCCGTGTGT CGGACGCGCG TCTACACCAA CCACTGGGCA
    GTCAAAATCG CCGGGGGCTT CCCGGAGGCC AACCGTATCG CCAGCAAGTA CGGATTCATC
    AACATAGGAC AGATAGGGGC CCTGAAGGAC TACTACCACT TCTACCATAG CAGGACGATT
    AAAAGGTCAG TTATCTCGAG CAGAGGGACC CACAGTTTCA TTTCAATGGA ACCAAAGGTG
    GAATGGATCC AACAGCAAGT GGTAAAAAAG CGGACAAAGA GGGATTATGA CTTCAGTCGT
    GCCCAGTCTA CCTATTTCAA TGATCCCAAG TGGCCCAGCA TGTGGTATAT GCACTGCAGT
    GACAATACAC ATCCCTGCCA GTCTGACATG AATATCGAAG GAGCCTGGAA GAGAGGCTAC
    ACGGGAAAGA ACATTGTGGT CACTATCCTG GATGACGGAA TTGAGAGAAC CCATCCAGAT
    CTGATGCAAA ACTACGATGC TCTGGCAAGT TGCGACGTGA ATGGGAATGA CTTGGACCCA
    ATGCCTCGTT ATGATGCAAG CAACGAGAAC AAGCATGGGA CTCGCTGTGC TGGAGAAGTG
    GCAGCCGCTG CAAACAATTC GCACTGCACA GTCGGAATTG CTTTCAACGC CAAGATCGGA
    GGAGTGCGAA TGCTGGACGG AGATGTCACG GACATGGTTG AAGCAAAATC AGTTAGCTTC
    AACCCCCAGC ACGTGCACAT TTACAGCGCC AGCTGGGGCC CGGATGATGA TGGCAAGACT
    GTGGACGGAC CAGCCCCCCT CACCCGGCAA GCCTTTGAAA ACGGCGTTAG AATGGGGCGG
    AGAGGCCTCG GCTCTGTGTT TGTTTGGGCA TCTGGAAATG GTGGAAGGAG CAAAGACCAC
    TGCTCCTGTG ATGGCTACAC CAACAGCATC TACACCATCT CCATCAGCAG CACTGCAGAA
    AGCGGAAAGA AACCTTGGTA CCTGGAAGAG TGTTCATCCA CGCTGGCCAC AACCTACAGC
    AGCGGGGAGT CCTACGATAA GAAAATCATC ACTACAGATC TGAGGCAGCG TTGCACGGAC
    AACCACACTG GGACGTCAGC CTCAGCCCCC ATGGCTGCAG GCATCATTGC GCTGGCCCTG
    GAAGCCAATC CGTTTCTGAC CTGGAGAGAC GTACAGCATG TTATTGTCAG GACTTCCCGT
    GCGGGACATT TGAACGCTAA TGACTGGAAA ACCAATGCTG CTGGTTTTAA GGTGAGCCAT
    CTTTATGGAT TTGGACTGAT GGACGCAGAA GCCATGGTGA TGGAGGCAGA GAAGTGGACC
    ACCGTTCCCC GGCAGCACGT GTGTGTGGAG AGCACAGACC GACAAATCAA GACAATCCGC
    CCTAACAGTG CAGTGCGCTC CATCTACAAA GCTTCAGGCT GCTCGGATAA CCCCAACCGC
    CATGTCAACT ACCTGGAGCA CGTCGTTGTG CGCATCACCA TCACCCACCC CAGGAGAGGA
    GACCTGGCCA TCTACCTGAC CTCGCCCTCT GGAACTAGGT CTCAGCTTTT GGCCAACAGG
    CTATTTGATC ACTCCATGGA AGGATTCAAA AACTGGGAGT TCATGACCAT TCATTGCTGG
    GGAGAAAGAG CTGCTGGTGA CTGGGTCCTT GAAGTTTATG ATACTCCCTC TCAGCTAAGG
    AACTTTAAGA CTCCAGGTAA ATTGAAAGAA TGGTCTTTGG TCCTCTACGG CACCTCCGTG
    CAGCCATATT CACCAACCAA TGAATTTCCG AAAGTGGAAC GGTTCCGCTA TAGCCGAGTT
    GAAGACCCCA CAGACGACTA TGGCACAGAG GATTATGCAG GTCCCTGCGA CCCTGAGTGC
    AGTGAGGTTG GCTGTGACGG GCCAGGACCA GACCACTGCA ATGACTGTTT GCACTACTAC
    TACAAGCTGA AAAACAATAC CAGGATCTGT GTCTCCAGCT GCCCCCCTGG CCACTACCAC
    GCCGACAAGA AGCGCTGCAG GAAGTGTGCC CCCAACTGTG AGTCCTGCTT TGGGAGCCAT
    GGTGACCAAT GCATGTCCTG CAAATATGGA TACTTTCTGA ATGAAGAAAC CAACAGCTGT
    GTTACTCACT GCCCTGATGG GTCATATCAG GATACCAAGA AAAATCTTTG CCGGAAATGC
    AGTGAAAACT GCAAGACATG TACTGAATTC CATAACTGTA CAGAATGTAG GGATGGGTTA
    AGCCTGCAGG GATCCCGGTG CTCTGTCTCC TGTGAAGATG GACGGTATTT CAACGGCCAG
    GACTGCCAGC CCTGCCACCG CTTCTGCGCC ACTTGTGCTG GGGCAGGAGC TGATGGGTGC
    ATTAACTGCA CAGAGGGCTA CTTCATGGAG GATGGGAGAT GCGTGCAGAG CTGTAGTATC
    AGCTATTACT TTGACCACTC TTCAGAGAAT GGATACAAAT CCTGCAAAAA ATGTGATATC
    AGTTGTTTGA CGTGCAATGG CCCAGGATTC AAGAACTGTA CAAGCTGCCC TAGTGGGTAT
    CTCTTAGACT TAGGAATGTG TCAAATGGGA GCCATTTGCA AGGATGCAAC GGAAGAGTCC
    TGGGCGGAAG GAGGCTTCTG TATGCTTGTG AAAAAGAACA ATCTGTGCCA ACGGAAGGTT
    CTTCAACAAC TTTGCTGCAA AACATGTACA TTTCAAGGCT GA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu98687
    Clone ID Related Accession (Same CDS sequence) XM_017014800.1
    Accession Version XM_017014800.1 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 4353bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-05
    Organism Homo sapiens(human)
    Product proprotein convertase subtilisin/kexin type 5 isoform X4
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    4201
    4261
    4321
    ATGAGCCATC TTTATGGATT TGGACTGATG GACGCAGAAG CCATGGTGAT GGAGGCAGAG 
    AAGTGGACCA CCGTTCCCCG GCAGCACGTG TGTGTGGAGA GCACAGACCG ACAAATCAAG
    ACAATCCGCC CTAACAGTGC AGTGCGCTCC ATCTACAAAG CTTCAGGCTG CTCGGATAAC
    CCCAACCGCC ATGTCAACTA CCTGGAGCAC GTCGTTGTGC GCATCACCAT CACCCACCCC
    AGGAGAGGAG ACCTGGCCAT CTACCTGACC TCGCCCTCTG GAACTAGGTC TCAGCTTTTG
    GCCAACAGGC TATTTGATCA CTCCATGGAA GGATTCAAAA ACTGGGAGTT CATGACCATT
    CATTGCTGGG GAGAAAGAGC TGCTGGTGAC TGGGTCCTTG AAGTTTATGA TACTCCCTCT
    CAGCTAAGGA ACTTTAAGAC TCCAGGTAAA TTGAAAGAAT GGTCTTTGGT CCTCTACGGC
    ACCTCCGTGC AGCCATATTC ACCAACCAAT GAATTTCCGA AAGTGGAACG GTTCCGCTAT
    AGCCGAGTTG AAGACCCCAC AGACGACTAT GGCACAGAGG ATTATGCAGG TCCCTGCGAC
    CCTGAGTGCA GTGAGGTTGG CTGTGACGGG CCAGGACCAG ACCACTGCAA TGACTGTTTG
    CACTACTACT ACAAGCTGAA AAACAATACC AGGATCTGTG TCTCCAGCTG CCCCCCTGGC
    CACTACCACG CCGACAAGAA GCGCTGCAGG AAGTGTGCCC CCAACTGTGA GTCCTGCTTT
    GGGAGCCATG GTGACCAATG CATGTCCTGC AAATATGGAT ACTTTCTGAA TGAAGAAACC
    AACAGCTGTG TTACTCACTG CCCTGATGGG TCATATCAGG ATACCAAGAA AAATCTTTGC
    CGGAAATGCA GTGAAAACTG CAAGACATGT ACTGAATTCC ATAACTGTAC AGAATGTAGG
    GATGGGTTAA GCCTGCAGGG ATCCCGGTGC TCTGTCTCCT GTGAAGATGG ACGGTATTTC
    AACGGCCAGG ACTGCCAGCC CTGCCACCGC TTCTGCGCCA CTTGTGCTGG GGCAGGAGCT
    GATGGGTGCA TTAACTGCAC AGAGGGCTAC TTCATGGAGG ATGGGAGATG CGTGCAGAGC
    TGTAGTATCA GCTATTACTT TGACCACTCT TCAGAGAATG GATACAAATC CTGCAAAAAA
    TGTGATATCA GTTGTTTGAC GTGCAATGGC CCAGGATTCA AGAACTGTAC AAGCTGCCCT
    AGTGGGTATC TCTTAGACTT AGGAATGTGT CAAATGGGAG CCATTTGCAA GGATGGAGAA
    TATGTTGATG AGCATGGCCA CTGCCAGACC TGTGAGGCCT CATGTGCCAA GTGCCAGGGA
    CCAACCCAGG AAGACTGCAC TACCTGCCCC ATGACAAGGA TTTTTGATGA TGGCCGCTGT
    GTTTCGAACT GCCCCTCATG GAAATTTGAA TTTGAGAACC AATGCCATCC ATGCCACCAC
    ACCTGCCAGA GATGCCAAGG AAGTGGCCCT ACCCACTGCA CCTCCTGTGG AGCAGACAAC
    TATGGCCGAG AGCACTTCCT GTACCAGGGA GAGTGTGGAG ATAGCTGCCC AGAGGGCCAC
    TATGCCACTG AGGGGAACAC CTGCCTGCCC TGCCCAGACA ACTGTGAGCT TTGCCACAGC
    GTGCATGTCT GCACAAGATG CATGAAGGGC TACTTCATAG CGCCCACCAA CCACACATGC
    CAGAAGTTAG AGTGTGGACA AGGTGAAGTC CAAGACCCAG ACTATGAAGA ATGTGTCCCT
    TGTGAAGAAG GATGTCTGGG ATGCAGCTTG GATGATCCAG GAACATGTAC ATCTTGCGCT
    ATGGGGTATT ACAGGTTTGA TCACCATTGT TATAAAACCT GTCCTGAGAA GACCTACAGT
    GAGGAAGTGG AATGCAAGGC GTGTGATAGT AACTGTGGCA GCTGTGACCA GAATGGGTGT
    TACTGGTGTG AAGAGGGCTT CTTTCTCTTA GGTGGCAGTT GTGTGAGGAA ATGTGGTCCT
    GGATTCTATG GTGACCAAGA AATGGGAGAA TGTGAGTCCT GCCACCGAGC ATGCGAAACC
    TGCACAGGCC CTGGTCATGA CGAGTGCAGC AGCTGCCAGG AAGGACTGCA GCTGCTGCGT
    GGGATGTGCG TGCATGCCAC CAAGACCCAG GAGGAGGGCA AATTCTGGAA TGAAGCTGTG
    TCCACTGCAA ACCTATCTGT GGTGAAGAGC CTGCTGCAGG AGCGACGAAG GTGGAAAGTT
    CAAATCAAAA GAGATATTTT GAGAAAACTC CAGCCTTGTC ATTCTTCTTG TAAAACCTGC
    AATGGATCTG CAACTCTGTG CACTTCATGT CCCAAAGGTG CATATCTTCT GGCTCAGGCC
    TGTGTTTCCT CCTGTCCCCA AGGCACATGG CCTTCCGTAA GGAGTGGGAG CTGCGAGAAC
    TGTACGGAGG CCTGTGCCAT CTGCTCTGGA GCCGATCTTT GCAAAAAATG CCAGATGCAG
    CCGGGCCACC CTCTCTTCCT CCATGAAGGC AGGTGCTACT CCAAGTGCCC GGAGGGCTCT
    TATGCAGAAG ACGGCATATG TGAACGCTGT AGCTCTCCTT GCAGAACATG TGAAGGAAAC
    GCCACCAACT GCCATTCTTG TGAAGGAGGC CACGTCCTGC ACCACGGAGT GTGCCAGGAA
    AACTGCCCCG AGAGGCACGT GGCTGTGAAG GGGGTATGCA AGCATTGCCC AGAGATGTGT
    CAGGACTGCA TCCATGAGAA AACATGCAAA GAGTGCACGC CTGAGTTCTT CCTGCACGAT
    GATATGTGCC ACCAGTCCTG TCCCCGTGGC TTCTATGCAG ACTCGCGCCA CTGTGTCCCC
    TGCCATAAAG ACTGTCTGGA GTGCAGTGGC CCCAAAGCCG ACGACTGCGA GCTCTGTCTT
    GAGAGTTCCT GGGTCCTCTA TGATGGACTG TGCTTGGAGG AGTGTCCAGC AGGAACCTAT
    TATGAAAAGG AGACTAAGGA GTGCAGAGAT TGCCACAAGT CCTGCTTGAC CTGCTCATCA
    TCTGGGACCT GCACCACCTG TCAGAAAGGC CTGATCATGA ACCCTCGTGG GAGCTGCATG
    GCCAACGAGA AGTGCTCACC CTCCGAGTAC TGGGATGAGG ATGCTCCCGG GTGCAAGCCC
    TGCCATGTTA AGTGCTTCCA CTGCATGGGG CCGGCGGAGG ACCAGTGTCA AACATGCCCC
    ATGAACAGCC TTCTTCTCAA CACAACCTGT GTGAAGGACT GCCCAGAGGG CTATTATGCC
    GATGAGGACA GCAACCGGTG TGCCCACTGC CACAGCTCTT GCAGGACATG TGAAGGGAGA
    CACAGCAGGC AGTGCCACTC CTGCCGACCG GGCTGGTTCC AGCTAGGAAA AGAGTGCCTG
    CTCCAGTGCA GGGAAGGATA TTACGCAGAC AACTCCACTG GCCGGTGTGA GAGGTGCAAC
    AGGAGCTGCA AGGGGTGCCA GGGCCCACGG CCCACAGACT GCCTGTCTTG CGATAGATTT
    TTCTTTCTGC TCCGCTCCAA AGGAGAGTGT CATCGCTCCT GCCCAGACCA TTACTATGTA
    GAGCAAAGCA CACAGACCTG TGAGAGATGC CATCCGACTT GTGATCAATG CAAAGGAAAA
    GGAGCGTTGA ATTGTTTATC CTGTGTGTGG AGTTACCACC TCATGGGAGG GATCTGCACC
    TCGGACTGTC TTGTGGGGGA ATACAGAGTG GGAGAGGGAG AGAAGTTTAA CTGTGAAAAA
    TGCCACGAGA GCTGCATGGA ATGCAAGGGA CCAGGGGCCA AGAACTGCAC CTTGTGCCCT
    GCCAACCTGG TGCTGCACAT GGACGACAGC CACTGCCTCC ACTGCTGCAA CACCTCTGAT
    CCCCCCAGTG CCCAGGAGTG CTGTGACTGC CAGGACACCA CGGACGAATG CATCCTTCGA
    ACAAGCAAGG TTAGGCCTGC AACTGAGCAT TTCAAGACAG CTCTGTTCAT CACCTCCTCC
    ATGATGCTGG TGCTTCTGCT CGGGGCAGCT GTGGTAGTGT GGAAGAAATC TCGTGGCCGA
    GTCCAGCCAG CAGCAAAGGC CGGCTATGAA AAACTGGCCG ACCCCAACAA GTCTTACTCC
    TCCTATAAGA GCAGCTATAG AGAGAGCACC AGCTTTGAAG AGGATCAGGT GATTGAGTAC
    AGGGATCGGG ACTATGATGA GGATGATGAT GATGACATCG TCTACATGGG CCAGGATGGC
    ACAGTCTACC GGAAATTTAA ATATGGGCTG CTGGATGACG ATGACATAGA TGAGCTGGAA
    TATGATGACG AGAGTTACTC CTACTACCAG TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_016870289.1
    CDS166..4518
    Translation

    Target ORF information:

    RefSeq Version XM_017014800.1
    Organism Homo sapiens(human)
    Definition Homo sapiens proprotein convertase subtilisin/kexin type 5 (PCSK5), transcript variant X4, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_017014800.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    4201
    4261
    4321
    ATGAGCCATC TTTATGGATT TGGACTGATG GACGCAGAAG CCATGGTGAT GGAGGCAGAG 
    AAGTGGACCA CCGTTCCCCG GCAGCACGTG TGTGTGGAGA GCACAGACCG ACAAATCAAG
    ACAATCCGCC CTAACAGTGC AGTGCGCTCC ATCTACAAAG CTTCAGGCTG CTCGGATAAC
    CCCAACCGCC ATGTCAACTA CCTGGAGCAC GTCGTTGTGC GCATCACCAT CACCCACCCC
    AGGAGAGGAG ACCTGGCCAT CTACCTGACC TCGCCCTCTG GAACTAGGTC TCAGCTTTTG
    GCCAACAGGC TATTTGATCA CTCCATGGAA GGATTCAAAA ACTGGGAGTT CATGACCATT
    CATTGCTGGG GAGAAAGAGC TGCTGGTGAC TGGGTCCTTG AAGTTTATGA TACTCCCTCT
    CAGCTAAGGA ACTTTAAGAC TCCAGGTAAA TTGAAAGAAT GGTCTTTGGT CCTCTACGGC
    ACCTCCGTGC AGCCATATTC ACCAACCAAT GAATTTCCGA AAGTGGAACG GTTCCGCTAT
    AGCCGAGTTG AAGACCCCAC AGACGACTAT GGCACAGAGG ATTATGCAGG TCCCTGCGAC
    CCTGAGTGCA GTGAGGTTGG CTGTGACGGG CCAGGACCAG ACCACTGCAA TGACTGTTTG
    CACTACTACT ACAAGCTGAA AAACAATACC AGGATCTGTG TCTCCAGCTG CCCCCCTGGC
    CACTACCACG CCGACAAGAA GCGCTGCAGG AAGTGTGCCC CCAACTGTGA GTCCTGCTTT
    GGGAGCCATG GTGACCAATG CATGTCCTGC AAATATGGAT ACTTTCTGAA TGAAGAAACC
    AACAGCTGTG TTACTCACTG CCCTGATGGG TCATATCAGG ATACCAAGAA AAATCTTTGC
    CGGAAATGCA GTGAAAACTG CAAGACATGT ACTGAATTCC ATAACTGTAC AGAATGTAGG
    GATGGGTTAA GCCTGCAGGG ATCCCGGTGC TCTGTCTCCT GTGAAGATGG ACGGTATTTC
    AACGGCCAGG ACTGCCAGCC CTGCCACCGC TTCTGCGCCA CTTGTGCTGG GGCAGGAGCT
    GATGGGTGCA TTAACTGCAC AGAGGGCTAC TTCATGGAGG ATGGGAGATG CGTGCAGAGC
    TGTAGTATCA GCTATTACTT TGACCACTCT TCAGAGAATG GATACAAATC CTGCAAAAAA
    TGTGATATCA GTTGTTTGAC GTGCAATGGC CCAGGATTCA AGAACTGTAC AAGCTGCCCT
    AGTGGGTATC TCTTAGACTT AGGAATGTGT CAAATGGGAG CCATTTGCAA GGATGGAGAA
    TATGTTGATG AGCATGGCCA CTGCCAGACC TGTGAGGCCT CATGTGCCAA GTGCCAGGGA
    CCAACCCAGG AAGACTGCAC TACCTGCCCC ATGACAAGGA TTTTTGATGA TGGCCGCTGT
    GTTTCGAACT GCCCCTCATG GAAATTTGAA TTTGAGAACC AATGCCATCC ATGCCACCAC
    ACCTGCCAGA GATGCCAAGG AAGTGGCCCT ACCCACTGCA CCTCCTGTGG AGCAGACAAC
    TATGGCCGAG AGCACTTCCT GTACCAGGGA GAGTGTGGAG ATAGCTGCCC AGAGGGCCAC
    TATGCCACTG AGGGGAACAC CTGCCTGCCC TGCCCAGACA ACTGTGAGCT TTGCCACAGC
    GTGCATGTCT GCACAAGATG CATGAAGGGC TACTTCATAG CGCCCACCAA CCACACATGC
    CAGAAGTTAG AGTGTGGACA AGGTGAAGTC CAAGACCCAG ACTATGAAGA ATGTGTCCCT
    TGTGAAGAAG GATGTCTGGG ATGCAGCTTG GATGATCCAG GAACATGTAC ATCTTGCGCT
    ATGGGGTATT ACAGGTTTGA TCACCATTGT TATAAAACCT GTCCTGAGAA GACCTACAGT
    GAGGAAGTGG AATGCAAGGC GTGTGATAGT AACTGTGGCA GCTGTGACCA GAATGGGTGT
    TACTGGTGTG AAGAGGGCTT CTTTCTCTTA GGTGGCAGTT GTGTGAGGAA ATGTGGTCCT
    GGATTCTATG GTGACCAAGA AATGGGAGAA TGTGAGTCCT GCCACCGAGC ATGCGAAACC
    TGCACAGGCC CTGGTCATGA CGAGTGCAGC AGCTGCCAGG AAGGACTGCA GCTGCTGCGT
    GGGATGTGCG TGCATGCCAC CAAGACCCAG GAGGAGGGCA AATTCTGGAA TGAAGCTGTG
    TCCACTGCAA ACCTATCTGT GGTGAAGAGC CTGCTGCAGG AGCGACGAAG GTGGAAAGTT
    CAAATCAAAA GAGATATTTT GAGAAAACTC CAGCCTTGTC ATTCTTCTTG TAAAACCTGC
    AATGGATCTG CAACTCTGTG CACTTCATGT CCCAAAGGTG CATATCTTCT GGCTCAGGCC
    TGTGTTTCCT CCTGTCCCCA AGGCACATGG CCTTCCGTAA GGAGTGGGAG CTGCGAGAAC
    TGTACGGAGG CCTGTGCCAT CTGCTCTGGA GCCGATCTTT GCAAAAAATG CCAGATGCAG
    CCGGGCCACC CTCTCTTCCT CCATGAAGGC AGGTGCTACT CCAAGTGCCC GGAGGGCTCT
    TATGCAGAAG ACGGCATATG TGAACGCTGT AGCTCTCCTT GCAGAACATG TGAAGGAAAC
    GCCACCAACT GCCATTCTTG TGAAGGAGGC CACGTCCTGC ACCACGGAGT GTGCCAGGAA
    AACTGCCCCG AGAGGCACGT GGCTGTGAAG GGGGTATGCA AGCATTGCCC AGAGATGTGT
    CAGGACTGCA TCCATGAGAA AACATGCAAA GAGTGCACGC CTGAGTTCTT CCTGCACGAT
    GATATGTGCC ACCAGTCCTG TCCCCGTGGC TTCTATGCAG ACTCGCGCCA CTGTGTCCCC
    TGCCATAAAG ACTGTCTGGA GTGCAGTGGC CCCAAAGCCG ACGACTGCGA GCTCTGTCTT
    GAGAGTTCCT GGGTCCTCTA TGATGGACTG TGCTTGGAGG AGTGTCCAGC AGGAACCTAT
    TATGAAAAGG AGACTAAGGA GTGCAGAGAT TGCCACAAGT CCTGCTTGAC CTGCTCATCA
    TCTGGGACCT GCACCACCTG TCAGAAAGGC CTGATCATGA ACCCTCGTGG GAGCTGCATG
    GCCAACGAGA AGTGCTCACC CTCCGAGTAC TGGGATGAGG ATGCTCCCGG GTGCAAGCCC
    TGCCATGTTA AGTGCTTCCA CTGCATGGGG CCGGCGGAGG ACCAGTGTCA AACATGCCCC
    ATGAACAGCC TTCTTCTCAA CACAACCTGT GTGAAGGACT GCCCAGAGGG CTATTATGCC
    GATGAGGACA GCAACCGGTG TGCCCACTGC CACAGCTCTT GCAGGACATG TGAAGGGAGA
    CACAGCAGGC AGTGCCACTC CTGCCGACCG GGCTGGTTCC AGCTAGGAAA AGAGTGCCTG
    CTCCAGTGCA GGGAAGGATA TTACGCAGAC AACTCCACTG GCCGGTGTGA GAGGTGCAAC
    AGGAGCTGCA AGGGGTGCCA GGGCCCACGG CCCACAGACT GCCTGTCTTG CGATAGATTT
    TTCTTTCTGC TCCGCTCCAA AGGAGAGTGT CATCGCTCCT GCCCAGACCA TTACTATGTA
    GAGCAAAGCA CACAGACCTG TGAGAGATGC CATCCGACTT GTGATCAATG CAAAGGAAAA
    GGAGCGTTGA ATTGTTTATC CTGTGTGTGG AGTTACCACC TCATGGGAGG GATCTGCACC
    TCGGACTGTC TTGTGGGGGA ATACAGAGTG GGAGAGGGAG AGAAGTTTAA CTGTGAAAAA
    TGCCACGAGA GCTGCATGGA ATGCAAGGGA CCAGGGGCCA AGAACTGCAC CTTGTGCCCT
    GCCAACCTGG TGCTGCACAT GGACGACAGC CACTGCCTCC ACTGCTGCAA CACCTCTGAT
    CCCCCCAGTG CCCAGGAGTG CTGTGACTGC CAGGACACCA CGGACGAATG CATCCTTCGA
    ACAAGCAAGG TTAGGCCTGC AACTGAGCAT TTCAAGACAG CTCTGTTCAT CACCTCCTCC
    ATGATGCTGG TGCTTCTGCT CGGGGCAGCT GTGGTAGTGT GGAAGAAATC TCGTGGCCGA
    GTCCAGCCAG CAGCAAAGGC CGGCTATGAA AAACTGGCCG ACCCCAACAA GTCTTACTCC
    TCCTATAAGA GCAGCTATAG AGAGAGCACC AGCTTTGAAG AGGATCAGGT GATTGAGTAC
    AGGGATCGGG ACTATGATGA GGATGATGAT GATGACATCG TCTACATGGG CCAGGATGGC
    ACAGTCTACC GGAAATTTAA ATATGGGCTG CTGGATGACG ATGACATAGA TGAGCTGGAA
    TATGATGACG AGAGTTACTC CTACTACCAG TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu43330
    Clone ID Related Accession (Same CDS sequence) XM_005252039.3 , NM_001372043.1 , XM_005252039.4
    Accession Version NM_001372043.1 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 5664bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-09-14
    Organism Homo sapiens(human)
    Product proprotein convertase subtilisin/kexin type 5 isoform 3 precursor
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL359253.17, AL353607.20, AL589653.9 and AL391868.16. On Aug 2, 2019 this sequence version replaced XM_005252039.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology RefSeq Select criteria :: based on manual assertion, conservation, expression, longest protein ##RefSeq-Attributes-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    4201
    4261
    4321
    4381
    4441
    4501
    4561
    4621
    4681
    4741
    4801
    4861
    4921
    4981
    5041
    5101
    5161
    5221
    5281
    5341
    5401
    5461
    5521
    5581
    5641
    ATGGGCTGGG GGAGCCGCTG CTGCTGCCCG GGACGTTTGG ACCTGCTGTG CGTGCTGGCG 
    CTGCTCGGGG GCTGCCTGCT CCCCGTGTGT CGGACGCGCG TCTACACCAA CCACTGGGCA
    GTCAAAATCG CCGGGGGCTT CCCGGAGGCC AACCGTATCG CCAGCAAGTA CGGATTCATC
    AACATAGGAC AGATAGGGGC CCTGAAGGAC TACTACCACT TCTACCATAG CAGGACGATT
    AAAAGGTCAG TTATCTCGAG CAGAGGGACC CACAGTTTCA TTTCAATGGA ACCAAAGGTG
    GAATGGATCC AACAGCAAGT GGTAAAAAAG CGGACAAAGA GGGATTATGA CTTCAGTCGT
    GCCCAGTCTA CCTATTTCAA TGATCCCAAG TGGCCCAGCA TGTGGTATAT GCACTGCAGT
    GACAATACAC ATCCCTGCCA GTCTGACATG AATATCGAAG GAGCCTGGAA GAGAGGCTAC
    ACGGGAAAGA ACATTGTGGT CACTATCCTG GATGACGGAA TTGAGAGAAC CCATCCAGAT
    CTGATGCAAA ACTACGATGC TCTGGCAAGT TGCGACGTGA ATGGGAATGA CTTGGACCCA
    ATGCCTCGTT ATGATGCAAG CAACGAGAAC AAGCATGGGA CTCGCTGTGC TGGAGAAGTG
    GCAGCCGCTG CAAACAATTC GCACTGCACA GTCGGAATTG CTTTCAACGC CAAGATCGGA
    GGAGTGCGAA TGCTGGACGG AGATGTCACG GACATGGTTG AAGCAAAATC AGTTAGCTTC
    AACCCCCAGC ACGTGCACAT TTACAGCGCC AGCTGGGGCC CGGATGATGA TGGCAAGACT
    GTGGACGGAC CAGCCCCCCT CACCCGGCAA GCCTTTGAAA ACGGCGTTAG AATGGGGCGG
    AGAGGCCTCG GCTCTGTGTT TGTTTGGGCA TCTGGAAATG GTGGAAGGAG CAAAGACCAC
    TGCTCCTGTG ATGGCTACAC CAACAGCATC TACACCATCT CCATCAGCAG CACTGCAGAA
    AGCGGAAAGA AACCTTGGTA CCTGGAAGAG TGTTCATCCA CGCTGGCCAC AACCTACAGC
    AGCGGGGAGT CCTACGATAA GAAAATCATC ACTACAGATC TGAGGCAGCG TTGCACGGAC
    AACCACACTG GGACGTCAGC CTCAGCCCCC ATGGCTGCAG GCATCATTGC GCTGGCCCTG
    GAAGCCAATC CGTTTCTGAC CTGGAGAGAC GTACAGCATG TTATTGTCAG GACTTCCCGT
    GCGGGACATT TGAACGCTAA TGACTGGAAA ACCAATGCTG CTGGTTTTAA GGTGAGCCAT
    CTTTATGGAT TTGGACTGAT GGACGCAGAA GCCATGGTGA TGGAGGCAGA GAAGTGGACC
    ACCGTTCCCC GGCAGCACGT GTGTGTGGAG AGCACAGACC GACAAATCAA GACAATCCGC
    CCTAACAGTG CAGTGCGCTC CATCTACAAA GCTTCAGGCT GCTCGGATAA CCCCAACCGC
    CATGTCAACT ACCTGGAGCA CGTCGTTGTG CGCATCACCA TCACCCACCC CAGGAGAGGA
    GACCTGGCCA TCTACCTGAC CTCGCCCTCT GGAACTAGGT CTCAGCTTTT GGCCAACAGG
    CTATTTGATC ACTCCATGGA AGGATTCAAA AACTGGGAGT TCATGACCAT TCATTGCTGG
    GGAGAAAGAG CTGCTGGTGA CTGGGTCCTT GAAGTTTATG ATACTCCCTC TCAGCTAAGG
    AACTTTAAGA CTCCAGGTAA ATTGAAAGAA TGGTCTTTGG TCCTCTACGG CACCTCCGTG
    CAGCCATATT CACCAACCAA TGAATTTCCG AAAGTGGAAC GGTTCCGCTA TAGCCGAGTT
    GAAGACCCCA CAGACGACTA TGGCACAGAG GATTATGCAG GTCCCTGCGA CCCTGAGTGC
    AGTGAGGTTG GCTGTGACGG GCCAGGACCA GACCACTGCA ATGACTGTTT GCACTACTAC
    TACAAGCTGA AAAACAATAC CAGGATCTGT GTCTCCAGCT GCCCCCCTGG CCACTACCAC
    GCCGACAAGA AGCGCTGCAG GAAGTGTGCC CCCAACTGTG AGTCCTGCTT TGGGAGCCAT
    GGTGACCAAT GCATGTCCTG CAAATATGGA TACTTTCTGA ATGAAGAAAC CAACAGCTGT
    GTTACTCACT GCCCTGATGG GTCATATCAG GATACCAAGA AAAATCTTTG CCGGAAATGC
    AGTGAAAACT GCAAGACATG TACTGAATTC CATAACTGTA CAGAATGTAG GGATGGGTTA
    AGCCTGCAGG GATCCCGGTG CTCTGTCTCC TGTGAAGATG GACGGTATTT CAACGGCCAG
    GACTGCCAGC CCTGCCACCG CTTCTGCGCC ACTTGTGCTG GGGCAGGAGC TGATGGGTGC
    ATTAACTGCA CAGAGGGCTA CTTCATGGAG GATGGGAGAT GCGTGCAGAG CTGTAGTATC
    AGCTATTACT TTGACCACTC TTCAGAGAAT GGATACAAAT CCTGCAAAAA ATGTGATATC
    AGTTGTTTGA CGTGCAATGG CCCAGGATTC AAGAACTGTA CAAGCTGCCC TAGTGGGTAT
    CTCTTAGACT TAGGAATGTG TCAAATGGGA GCCATTTGCA AGGATGGAGA ATATGTTGAT
    GAGCATGGCC ACTGCCAGAC CTGTGAGGCC TCATGTGCCA AGTGCCAGGG ACCAACCCAG
    GAAGACTGCA CTACCTGCCC CATGACAAGG ATTTTTGATG ATGGCCGCTG TGTTTCGAAC
    TGCCCCTCAT GGAAATTTGA ATTTGAGAAC CAATGCCATC CATGCCACCA CACCTGCCAG
    AGATGCCAAG GAAGTGGCCC TACCCACTGC ACCTCCTGTG GAGCAGACAA CTATGGCCGA
    GAGCACTTCC TGTACCAGGG AGAGTGTGGA GATAGCTGCC CAGAGGGCCA CTATGCCACT
    GAGGGGAACA CCTGCCTGCC CTGCCCAGAC AACTGTGAGC TTTGCCACAG CGTGCATGTC
    TGCACAAGAT GCATGAAGGG CTACTTCATA GCGCCCACCA ACCACACATG CCAGAAGTTA
    GAGTGTGGAC AAGGTGAAGT CCAAGACCCA GACTATGAAG AATGTGTCCC TTGTGAAGAA
    GGATGTCTGG GATGCAGCTT GGATGATCCA GGAACATGTA CATCTTGCGC TATGGGGTAT
    TACAGGTTTG ATCACCATTG TTATAAAACC TGTCCTGAGA AGACCTACAG TGAGGAAGTG
    GAATGCAAGG CGTGTGATAG TAACTGTGGC AGCTGTGACC AGAATGGGTG TTACTGGTGT
    GAAGAGGGCT TCTTTCTCTT AGGTGGCAGT TGTGTGAGGA AATGTGGTCC TGGATTCTAT
    GGTGACCAAG AAATGGGAGA ATGTGAGTCC TGCCACCGAG CATGCGAAAC CTGCACAGGC
    CCTGGTCATG ACGAGTGCAG CAGCTGCCAG GAAGGACTGC AGCTGCTGCG TGGGATGTGC
    GTGCATGCCA CCAAGACCCA GGAGGAGGGC AAATTCTGGA ATGAAGCTGT GTCCACTGCA
    AACCTATCTG TGGTGAAGAG CCTGCTGCAG GAGCGACGAA GGTGGAAAGT TCAAATCAAA
    AGAGATATTT TGAGAAAACT CCAGCCTTGT CATTCTTCTT GTAAAACCTG CAATGGATCT
    GCAACTCTGT GCACTTCATG TCCCAAAGGT GCATATCTTC TGGCTCAGGC CTGTGTTTCC
    TCCTGTCCCC AAGGCACATG GCCTTCCGTA AGGAGTGGGA GCTGCGAGAA CTGTACGGAG
    GCCTGTGCCA TCTGCTCTGG AGCCGATCTT TGCAAAAAAT GCCAGATGCA GCCGGGCCAC
    CCTCTCTTCC TCCATGAAGG CAGGTGCTAC TCCAAGTGCC CGGAGGGCTC TTATGCAGAA
    GACGGCATAT GTGAACGCTG TAGCTCTCCT TGCAGAACAT GTGAAGGAAA CGCCACCAAC
    TGCCATTCTT GTGAAGGAGG CCACGTCCTG CACCACGGAG TGTGCCAGGA AAACTGCCCC
    GAGAGGCACG TGGCTGTGAA GGGGGTATGC AAGCATTGCC CAGAGATGTG TCAGGACTGC
    ATCCATGAGA AAACATGCAA AGAGTGCACG CCTGAGTTCT TCCTGCACGA TGATATGTGC
    CACCAGTCCT GTCCCCGTGG CTTCTATGCA GACTCGCGCC ACTGTGTCCC CTGCCATAAA
    GACTGTCTGG AGTGCAGTGG CCCCAAAGCC GACGACTGCG AGCTCTGTCT TGAGAGTTCC
    TGGGTCCTCT ATGATGGACT GTGCTTGGAG GAGTGTCCAG CAGGAACCTA TTATGAAAAG
    GAGACTAAGG AGTGCAGAGA TTGCCACAAG TCCTGCTTGA CCTGCTCATC ATCTGGGACC
    TGCACCACCT GTCAGAAAGG CCTGATCATG AACCCTCGTG GGAGCTGCAT GGCCAACGAG
    AAGTGCTCAC CCTCCGAGTA CTGGGATGAG GATGCTCCCG GGTGCAAGCC CTGCCATGTT
    AAGTGCTTCC ACTGCATGGG GCCGGCGGAG GACCAGTGTC AAACATGCCC CATGAACAGC
    CTTCTTCTCA ACACAACCTG TGTGAAGGAC TGCCCAGAGG GCTATTATGC CGATGAGGAC
    AGCAACCGGT GTGCCCACTG CCACAGCTCT TGCAGGACAT GTGAAGGGAG ACACAGCAGG
    CAGTGCCACT CCTGCCGACC GGGCTGGTTC CAGCTAGGAA AAGAGTGCCT GCTCCAGTGC
    AGGGAAGGAT ATTACGCAGA CAACTCCACT GGCCGGTGTG AGAGGTGCAA CAGGAGCTGC
    AAGGGGTGCC AGGGCCCACG GCCCACAGAC TGCCTGTCTT GCGATAGATT TTTCTTTCTG
    CTCCGCTCCA AAGGAGAGTG TCATCGCTCC TGCCCAGACC ATTACTATGT AGAGCAAAGC
    ACACAGACCT GTGAGAGATG CCATCCGACT TGTGATCAAT GCAAAGGAAA AGGAGCGTTG
    AATTGTTTAT CCTGTGTGTG GAGTTACCAC CTCATGGGAG GGATCTGCAC CTCGGACTGT
    CTTGTGGGGG AATACAGAGT GGGAGAGGGA GAGAAGTTTA ACTGTGAAAA ATGCCACGAG
    AGCTGCATGG AATGCAAGGG ACCAGGGGCC AAGAACTGCA CCTTGTGCCC TGCCAACCTG
    GTGCTGCACA TGGACGACAG CCACTGCCTC CACTGCTGCA ACACCTCTGA TCCCCCCAGT
    GCCCAGGAGT GCTGTGACTG CCAGGACACC ACGGACGAAT GCATCCTTCG AACAAGCAAG
    GTTAGGCCTG CAACTGAGCA TTTCAAGACA GCTCTGTTCA TCACCTCCTC CATGATGCTG
    GTGCTTCTGC TCGGGGCAGC TGTGGTAGTG TGGAAGAAAT CTCGTGGCCG AGTCCAGCCA
    GCAGCAAAGG CCGGCTATGA AAAACTGGCC GACCCCAACA AGTCTTACTC CTCCTATAAG
    AGCAGCTATA GAGAGAGCAC CAGCTTTGAA GAGGATCAGG TGATTGAGTA CAGGGATCGG
    GACTATGATG AGGATGATGA TGATGACATC GTCTACATGG GCCAGGATGG CACAGTCTAC
    CGGAAATTTA AATATGGGCT GCTGGATGAC GATGACATAG ATGAGCTGGA ATATGATGAC
    GAGAGTTACT CCTACTACCA GTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001358972.1
    CDS510..6173
    Translation

    Target ORF information:

    RefSeq Version NM_001372043.1
    Organism Homo sapiens(human)
    Definition Homo sapiens proprotein convertase subtilisin/kexin type 5 (PCSK5), transcript variant 4, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001372043.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    4201
    4261
    4321
    4381
    4441
    4501
    4561
    4621
    4681
    4741
    4801
    4861
    4921
    4981
    5041
    5101
    5161
    5221
    5281
    5341
    5401
    5461
    5521
    5581
    5641
    ATGGGCTGGG GGAGCCGCTG CTGCTGCCCG GGACGTTTGG ACCTGCTGTG CGTGCTGGCG 
    CTGCTCGGGG GCTGCCTGCT CCCCGTGTGT CGGACGCGCG TCTACACCAA CCACTGGGCA
    GTCAAAATCG CCGGGGGCTT CCCGGAGGCC AACCGTATCG CCAGCAAGTA CGGATTCATC
    AACATAGGAC AGATAGGGGC CCTGAAGGAC TACTACCACT TCTACCATAG CAGGACGATT
    AAAAGGTCAG TTATCTCGAG CAGAGGGACC CACAGTTTCA TTTCAATGGA ACCAAAGGTG
    GAATGGATCC AACAGCAAGT GGTAAAAAAG CGGACAAAGA GGGATTATGA CTTCAGTCGT
    GCCCAGTCTA CCTATTTCAA TGATCCCAAG TGGCCCAGCA TGTGGTATAT GCACTGCAGT
    GACAATACAC ATCCCTGCCA GTCTGACATG AATATCGAAG GAGCCTGGAA GAGAGGCTAC
    ACGGGAAAGA ACATTGTGGT CACTATCCTG GATGACGGAA TTGAGAGAAC CCATCCAGAT
    CTGATGCAAA ACTACGATGC TCTGGCAAGT TGCGACGTGA ATGGGAATGA CTTGGACCCA
    ATGCCTCGTT ATGATGCAAG CAACGAGAAC AAGCATGGGA CTCGCTGTGC TGGAGAAGTG
    GCAGCCGCTG CAAACAATTC GCACTGCACA GTCGGAATTG CTTTCAACGC CAAGATCGGA
    GGAGTGCGAA TGCTGGACGG AGATGTCACG GACATGGTTG AAGCAAAATC AGTTAGCTTC
    AACCCCCAGC ACGTGCACAT TTACAGCGCC AGCTGGGGCC CGGATGATGA TGGCAAGACT
    GTGGACGGAC CAGCCCCCCT CACCCGGCAA GCCTTTGAAA ACGGCGTTAG AATGGGGCGG
    AGAGGCCTCG GCTCTGTGTT TGTTTGGGCA TCTGGAAATG GTGGAAGGAG CAAAGACCAC
    TGCTCCTGTG ATGGCTACAC CAACAGCATC TACACCATCT CCATCAGCAG CACTGCAGAA
    AGCGGAAAGA AACCTTGGTA CCTGGAAGAG TGTTCATCCA CGCTGGCCAC AACCTACAGC
    AGCGGGGAGT CCTACGATAA GAAAATCATC ACTACAGATC TGAGGCAGCG TTGCACGGAC
    AACCACACTG GGACGTCAGC CTCAGCCCCC ATGGCTGCAG GCATCATTGC GCTGGCCCTG
    GAAGCCAATC CGTTTCTGAC CTGGAGAGAC GTACAGCATG TTATTGTCAG GACTTCCCGT
    GCGGGACATT TGAACGCTAA TGACTGGAAA ACCAATGCTG CTGGTTTTAA GGTGAGCCAT
    CTTTATGGAT TTGGACTGAT GGACGCAGAA GCCATGGTGA TGGAGGCAGA GAAGTGGACC
    ACCGTTCCCC GGCAGCACGT GTGTGTGGAG AGCACAGACC GACAAATCAA GACAATCCGC
    CCTAACAGTG CAGTGCGCTC CATCTACAAA GCTTCAGGCT GCTCGGATAA CCCCAACCGC
    CATGTCAACT ACCTGGAGCA CGTCGTTGTG CGCATCACCA TCACCCACCC CAGGAGAGGA
    GACCTGGCCA TCTACCTGAC CTCGCCCTCT GGAACTAGGT CTCAGCTTTT GGCCAACAGG
    CTATTTGATC ACTCCATGGA AGGATTCAAA AACTGGGAGT TCATGACCAT TCATTGCTGG
    GGAGAAAGAG CTGCTGGTGA CTGGGTCCTT GAAGTTTATG ATACTCCCTC TCAGCTAAGG
    AACTTTAAGA CTCCAGGTAA ATTGAAAGAA TGGTCTTTGG TCCTCTACGG CACCTCCGTG
    CAGCCATATT CACCAACCAA TGAATTTCCG AAAGTGGAAC GGTTCCGCTA TAGCCGAGTT
    GAAGACCCCA CAGACGACTA TGGCACAGAG GATTATGCAG GTCCCTGCGA CCCTGAGTGC
    AGTGAGGTTG GCTGTGACGG GCCAGGACCA GACCACTGCA ATGACTGTTT GCACTACTAC
    TACAAGCTGA AAAACAATAC CAGGATCTGT GTCTCCAGCT GCCCCCCTGG CCACTACCAC
    GCCGACAAGA AGCGCTGCAG GAAGTGTGCC CCCAACTGTG AGTCCTGCTT TGGGAGCCAT
    GGTGACCAAT GCATGTCCTG CAAATATGGA TACTTTCTGA ATGAAGAAAC CAACAGCTGT
    GTTACTCACT GCCCTGATGG GTCATATCAG GATACCAAGA AAAATCTTTG CCGGAAATGC
    AGTGAAAACT GCAAGACATG TACTGAATTC CATAACTGTA CAGAATGTAG GGATGGGTTA
    AGCCTGCAGG GATCCCGGTG CTCTGTCTCC TGTGAAGATG GACGGTATTT CAACGGCCAG
    GACTGCCAGC CCTGCCACCG CTTCTGCGCC ACTTGTGCTG GGGCAGGAGC TGATGGGTGC
    ATTAACTGCA CAGAGGGCTA CTTCATGGAG GATGGGAGAT GCGTGCAGAG CTGTAGTATC
    AGCTATTACT TTGACCACTC TTCAGAGAAT GGATACAAAT CCTGCAAAAA ATGTGATATC
    AGTTGTTTGA CGTGCAATGG CCCAGGATTC AAGAACTGTA CAAGCTGCCC TAGTGGGTAT
    CTCTTAGACT TAGGAATGTG TCAAATGGGA GCCATTTGCA AGGATGGAGA ATATGTTGAT
    GAGCATGGCC ACTGCCAGAC CTGTGAGGCC TCATGTGCCA AGTGCCAGGG ACCAACCCAG
    GAAGACTGCA CTACCTGCCC CATGACAAGG ATTTTTGATG ATGGCCGCTG TGTTTCGAAC
    TGCCCCTCAT GGAAATTTGA ATTTGAGAAC CAATGCCATC CATGCCACCA CACCTGCCAG
    AGATGCCAAG GAAGTGGCCC TACCCACTGC ACCTCCTGTG GAGCAGACAA CTATGGCCGA
    GAGCACTTCC TGTACCAGGG AGAGTGTGGA GATAGCTGCC CAGAGGGCCA CTATGCCACT
    GAGGGGAACA CCTGCCTGCC CTGCCCAGAC AACTGTGAGC TTTGCCACAG CGTGCATGTC
    TGCACAAGAT GCATGAAGGG CTACTTCATA GCGCCCACCA ACCACACATG CCAGAAGTTA
    GAGTGTGGAC AAGGTGAAGT CCAAGACCCA GACTATGAAG AATGTGTCCC TTGTGAAGAA
    GGATGTCTGG GATGCAGCTT GGATGATCCA GGAACATGTA CATCTTGCGC TATGGGGTAT
    TACAGGTTTG ATCACCATTG TTATAAAACC TGTCCTGAGA AGACCTACAG TGAGGAAGTG
    GAATGCAAGG CGTGTGATAG TAACTGTGGC AGCTGTGACC AGAATGGGTG TTACTGGTGT
    GAAGAGGGCT TCTTTCTCTT AGGTGGCAGT TGTGTGAGGA AATGTGGTCC TGGATTCTAT
    GGTGACCAAG AAATGGGAGA ATGTGAGTCC TGCCACCGAG CATGCGAAAC CTGCACAGGC
    CCTGGTCATG ACGAGTGCAG CAGCTGCCAG GAAGGACTGC AGCTGCTGCG TGGGATGTGC
    GTGCATGCCA CCAAGACCCA GGAGGAGGGC AAATTCTGGA ATGAAGCTGT GTCCACTGCA
    AACCTATCTG TGGTGAAGAG CCTGCTGCAG GAGCGACGAA GGTGGAAAGT TCAAATCAAA
    AGAGATATTT TGAGAAAACT CCAGCCTTGT CATTCTTCTT GTAAAACCTG CAATGGATCT
    GCAACTCTGT GCACTTCATG TCCCAAAGGT GCATATCTTC TGGCTCAGGC CTGTGTTTCC
    TCCTGTCCCC AAGGCACATG GCCTTCCGTA AGGAGTGGGA GCTGCGAGAA CTGTACGGAG
    GCCTGTGCCA TCTGCTCTGG AGCCGATCTT TGCAAAAAAT GCCAGATGCA GCCGGGCCAC
    CCTCTCTTCC TCCATGAAGG CAGGTGCTAC TCCAAGTGCC CGGAGGGCTC TTATGCAGAA
    GACGGCATAT GTGAACGCTG TAGCTCTCCT TGCAGAACAT GTGAAGGAAA CGCCACCAAC
    TGCCATTCTT GTGAAGGAGG CCACGTCCTG CACCACGGAG TGTGCCAGGA AAACTGCCCC
    GAGAGGCACG TGGCTGTGAA GGGGGTATGC AAGCATTGCC CAGAGATGTG TCAGGACTGC
    ATCCATGAGA AAACATGCAA AGAGTGCACG CCTGAGTTCT TCCTGCACGA TGATATGTGC
    CACCAGTCCT GTCCCCGTGG CTTCTATGCA GACTCGCGCC ACTGTGTCCC CTGCCATAAA
    GACTGTCTGG AGTGCAGTGG CCCCAAAGCC GACGACTGCG AGCTCTGTCT TGAGAGTTCC
    TGGGTCCTCT ATGATGGACT GTGCTTGGAG GAGTGTCCAG CAGGAACCTA TTATGAAAAG
    GAGACTAAGG AGTGCAGAGA TTGCCACAAG TCCTGCTTGA CCTGCTCATC ATCTGGGACC
    TGCACCACCT GTCAGAAAGG CCTGATCATG AACCCTCGTG GGAGCTGCAT GGCCAACGAG
    AAGTGCTCAC CCTCCGAGTA CTGGGATGAG GATGCTCCCG GGTGCAAGCC CTGCCATGTT
    AAGTGCTTCC ACTGCATGGG GCCGGCGGAG GACCAGTGTC AAACATGCCC CATGAACAGC
    CTTCTTCTCA ACACAACCTG TGTGAAGGAC TGCCCAGAGG GCTATTATGC CGATGAGGAC
    AGCAACCGGT GTGCCCACTG CCACAGCTCT TGCAGGACAT GTGAAGGGAG ACACAGCAGG
    CAGTGCCACT CCTGCCGACC GGGCTGGTTC CAGCTAGGAA AAGAGTGCCT GCTCCAGTGC
    AGGGAAGGAT ATTACGCAGA CAACTCCACT GGCCGGTGTG AGAGGTGCAA CAGGAGCTGC
    AAGGGGTGCC AGGGCCCACG GCCCACAGAC TGCCTGTCTT GCGATAGATT TTTCTTTCTG
    CTCCGCTCCA AAGGAGAGTG TCATCGCTCC TGCCCAGACC ATTACTATGT AGAGCAAAGC
    ACACAGACCT GTGAGAGATG CCATCCGACT TGTGATCAAT GCAAAGGAAA AGGAGCGTTG
    AATTGTTTAT CCTGTGTGTG GAGTTACCAC CTCATGGGAG GGATCTGCAC CTCGGACTGT
    CTTGTGGGGG AATACAGAGT GGGAGAGGGA GAGAAGTTTA ACTGTGAAAA ATGCCACGAG
    AGCTGCATGG AATGCAAGGG ACCAGGGGCC AAGAACTGCA CCTTGTGCCC TGCCAACCTG
    GTGCTGCACA TGGACGACAG CCACTGCCTC CACTGCTGCA ACACCTCTGA TCCCCCCAGT
    GCCCAGGAGT GCTGTGACTG CCAGGACACC ACGGACGAAT GCATCCTTCG AACAAGCAAG
    GTTAGGCCTG CAACTGAGCA TTTCAAGACA GCTCTGTTCA TCACCTCCTC CATGATGCTG
    GTGCTTCTGC TCGGGGCAGC TGTGGTAGTG TGGAAGAAAT CTCGTGGCCG AGTCCAGCCA
    GCAGCAAAGG CCGGCTATGA AAAACTGGCC GACCCCAACA AGTCTTACTC CTCCTATAAG
    AGCAGCTATA GAGAGAGCAC CAGCTTTGAA GAGGATCAGG TGATTGAGTA CAGGGATCGG
    GACTATGATG AGGATGATGA TGATGACATC GTCTACATGG GCCAGGATGG CACAGTCTAC
    CGGAAATTTA AATATGGGCT GCTGGATGAC GATGACATAG ATGAGCTGGA ATATGATGAC
    GAGAGTTACT CCTACTACCA GTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu43330
    Clone ID Related Accession (Same CDS sequence) XM_005252039.3 , NM_001372043.1 , XM_005252039.4
    Accession Version XM_005252039.3 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 5664bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2016-06-05
    Organism Homo sapiens(human)
    Product proprotein convertase subtilisin/kexin type 5 isoform X1
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005252039.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    4201
    4261
    4321
    4381
    4441
    4501
    4561
    4621
    4681
    4741
    4801
    4861
    4921
    4981
    5041
    5101
    5161
    5221
    5281
    5341
    5401
    5461
    5521
    5581
    5641
    ATGGGCTGGG GGAGCCGCTG CTGCTGCCCG GGACGTTTGG ACCTGCTGTG CGTGCTGGCG 
    CTGCTCGGGG GCTGCCTGCT CCCCGTGTGT CGGACGCGCG TCTACACCAA CCACTGGGCA
    GTCAAAATCG CCGGGGGCTT CCCGGAGGCC AACCGTATCG CCAGCAAGTA CGGATTCATC
    AACATAGGAC AGATAGGGGC CCTGAAGGAC TACTACCACT TCTACCATAG CAGGACGATT
    AAAAGGTCAG TTATCTCGAG CAGAGGGACC CACAGTTTCA TTTCAATGGA ACCAAAGGTG
    GAATGGATCC AACAGCAAGT GGTAAAAAAG CGGACAAAGA GGGATTATGA CTTCAGTCGT
    GCCCAGTCTA CCTATTTCAA TGATCCCAAG TGGCCCAGCA TGTGGTATAT GCACTGCAGT
    GACAATACAC ATCCCTGCCA GTCTGACATG AATATCGAAG GAGCCTGGAA GAGAGGCTAC
    ACGGGAAAGA ACATTGTGGT CACTATCCTG GATGACGGAA TTGAGAGAAC CCATCCAGAT
    CTGATGCAAA ACTACGATGC TCTGGCAAGT TGCGACGTGA ATGGGAATGA CTTGGACCCA
    ATGCCTCGTT ATGATGCAAG CAACGAGAAC AAGCATGGGA CTCGCTGTGC TGGAGAAGTG
    GCAGCCGCTG CAAACAATTC GCACTGCACA GTCGGAATTG CTTTCAACGC CAAGATCGGA
    GGAGTGCGAA TGCTGGACGG AGATGTCACG GACATGGTTG AAGCAAAATC AGTTAGCTTC
    AACCCCCAGC ACGTGCACAT TTACAGCGCC AGCTGGGGCC CGGATGATGA TGGCAAGACT
    GTGGACGGAC CAGCCCCCCT CACCCGGCAA GCCTTTGAAA ACGGCGTTAG AATGGGGCGG
    AGAGGCCTCG GCTCTGTGTT TGTTTGGGCA TCTGGAAATG GTGGAAGGAG CAAAGACCAC
    TGCTCCTGTG ATGGCTACAC CAACAGCATC TACACCATCT CCATCAGCAG CACTGCAGAA
    AGCGGAAAGA AACCTTGGTA CCTGGAAGAG TGTTCATCCA CGCTGGCCAC AACCTACAGC
    AGCGGGGAGT CCTACGATAA GAAAATCATC ACTACAGATC TGAGGCAGCG TTGCACGGAC
    AACCACACTG GGACGTCAGC CTCAGCCCCC ATGGCTGCAG GCATCATTGC GCTGGCCCTG
    GAAGCCAATC CGTTTCTGAC CTGGAGAGAC GTACAGCATG TTATTGTCAG GACTTCCCGT
    GCGGGACATT TGAACGCTAA TGACTGGAAA ACCAATGCTG CTGGTTTTAA GGTGAGCCAT
    CTTTATGGAT TTGGACTGAT GGACGCAGAA GCCATGGTGA TGGAGGCAGA GAAGTGGACC
    ACCGTTCCCC GGCAGCACGT GTGTGTGGAG AGCACAGACC GACAAATCAA GACAATCCGC
    CCTAACAGTG CAGTGCGCTC CATCTACAAA GCTTCAGGCT GCTCGGATAA CCCCAACCGC
    CATGTCAACT ACCTGGAGCA CGTCGTTGTG CGCATCACCA TCACCCACCC CAGGAGAGGA
    GACCTGGCCA TCTACCTGAC CTCGCCCTCT GGAACTAGGT CTCAGCTTTT GGCCAACAGG
    CTATTTGATC ACTCCATGGA AGGATTCAAA AACTGGGAGT TCATGACCAT TCATTGCTGG
    GGAGAAAGAG CTGCTGGTGA CTGGGTCCTT GAAGTTTATG ATACTCCCTC TCAGCTAAGG
    AACTTTAAGA CTCCAGGTAA ATTGAAAGAA TGGTCTTTGG TCCTCTACGG CACCTCCGTG
    CAGCCATATT CACCAACCAA TGAATTTCCG AAAGTGGAAC GGTTCCGCTA TAGCCGAGTT
    GAAGACCCCA CAGACGACTA TGGCACAGAG GATTATGCAG GTCCCTGCGA CCCTGAGTGC
    AGTGAGGTTG GCTGTGACGG GCCAGGACCA GACCACTGCA ATGACTGTTT GCACTACTAC
    TACAAGCTGA AAAACAATAC CAGGATCTGT GTCTCCAGCT GCCCCCCTGG CCACTACCAC
    GCCGACAAGA AGCGCTGCAG GAAGTGTGCC CCCAACTGTG AGTCCTGCTT TGGGAGCCAT
    GGTGACCAAT GCATGTCCTG CAAATATGGA TACTTTCTGA ATGAAGAAAC CAACAGCTGT
    GTTACTCACT GCCCTGATGG GTCATATCAG GATACCAAGA AAAATCTTTG CCGGAAATGC
    AGTGAAAACT GCAAGACATG TACTGAATTC CATAACTGTA CAGAATGTAG GGATGGGTTA
    AGCCTGCAGG GATCCCGGTG CTCTGTCTCC TGTGAAGATG GACGGTATTT CAACGGCCAG
    GACTGCCAGC CCTGCCACCG CTTCTGCGCC ACTTGTGCTG GGGCAGGAGC TGATGGGTGC
    ATTAACTGCA CAGAGGGCTA CTTCATGGAG GATGGGAGAT GCGTGCAGAG CTGTAGTATC
    AGCTATTACT TTGACCACTC TTCAGAGAAT GGATACAAAT CCTGCAAAAA ATGTGATATC
    AGTTGTTTGA CGTGCAATGG CCCAGGATTC AAGAACTGTA CAAGCTGCCC TAGTGGGTAT
    CTCTTAGACT TAGGAATGTG TCAAATGGGA GCCATTTGCA AGGATGGAGA ATATGTTGAT
    GAGCATGGCC ACTGCCAGAC CTGTGAGGCC TCATGTGCCA AGTGCCAGGG ACCAACCCAG
    GAAGACTGCA CTACCTGCCC CATGACAAGG ATTTTTGATG ATGGCCGCTG TGTTTCGAAC
    TGCCCCTCAT GGAAATTTGA ATTTGAGAAC CAATGCCATC CATGCCACCA CACCTGCCAG
    AGATGCCAAG GAAGTGGCCC TACCCACTGC ACCTCCTGTG GAGCAGACAA CTATGGCCGA
    GAGCACTTCC TGTACCAGGG AGAGTGTGGA GATAGCTGCC CAGAGGGCCA CTATGCCACT
    GAGGGGAACA CCTGCCTGCC CTGCCCAGAC AACTGTGAGC TTTGCCACAG CGTGCATGTC
    TGCACAAGAT GCATGAAGGG CTACTTCATA GCGCCCACCA ACCACACATG CCAGAAGTTA
    GAGTGTGGAC AAGGTGAAGT CCAAGACCCA GACTATGAAG AATGTGTCCC TTGTGAAGAA
    GGATGTCTGG GATGCAGCTT GGATGATCCA GGAACATGTA CATCTTGCGC TATGGGGTAT
    TACAGGTTTG ATCACCATTG TTATAAAACC TGTCCTGAGA AGACCTACAG TGAGGAAGTG
    GAATGCAAGG CGTGTGATAG TAACTGTGGC AGCTGTGACC AGAATGGGTG TTACTGGTGT
    GAAGAGGGCT TCTTTCTCTT AGGTGGCAGT TGTGTGAGGA AATGTGGTCC TGGATTCTAT
    GGTGACCAAG AAATGGGAGA ATGTGAGTCC TGCCACCGAG CATGCGAAAC CTGCACAGGC
    CCTGGTCATG ACGAGTGCAG CAGCTGCCAG GAAGGACTGC AGCTGCTGCG TGGGATGTGC
    GTGCATGCCA CCAAGACCCA GGAGGAGGGC AAATTCTGGA ATGAAGCTGT GTCCACTGCA
    AACCTATCTG TGGTGAAGAG CCTGCTGCAG GAGCGACGAA GGTGGAAAGT TCAAATCAAA
    AGAGATATTT TGAGAAAACT CCAGCCTTGT CATTCTTCTT GTAAAACCTG CAATGGATCT
    GCAACTCTGT GCACTTCATG TCCCAAAGGT GCATATCTTC TGGCTCAGGC CTGTGTTTCC
    TCCTGTCCCC AAGGCACATG GCCTTCCGTA AGGAGTGGGA GCTGCGAGAA CTGTACGGAG
    GCCTGTGCCA TCTGCTCTGG AGCCGATCTT TGCAAAAAAT GCCAGATGCA GCCGGGCCAC
    CCTCTCTTCC TCCATGAAGG CAGGTGCTAC TCCAAGTGCC CGGAGGGCTC TTATGCAGAA
    GACGGCATAT GTGAACGCTG TAGCTCTCCT TGCAGAACAT GTGAAGGAAA CGCCACCAAC
    TGCCATTCTT GTGAAGGAGG CCACGTCCTG CACCACGGAG TGTGCCAGGA AAACTGCCCC
    GAGAGGCACG TGGCTGTGAA GGGGGTATGC AAGCATTGCC CAGAGATGTG TCAGGACTGC
    ATCCATGAGA AAACATGCAA AGAGTGCACG CCTGAGTTCT TCCTGCACGA TGATATGTGC
    CACCAGTCCT GTCCCCGTGG CTTCTATGCA GACTCGCGCC ACTGTGTCCC CTGCCATAAA
    GACTGTCTGG AGTGCAGTGG CCCCAAAGCC GACGACTGCG AGCTCTGTCT TGAGAGTTCC
    TGGGTCCTCT ATGATGGACT GTGCTTGGAG GAGTGTCCAG CAGGAACCTA TTATGAAAAG
    GAGACTAAGG AGTGCAGAGA TTGCCACAAG TCCTGCTTGA CCTGCTCATC ATCTGGGACC
    TGCACCACCT GTCAGAAAGG CCTGATCATG AACCCTCGTG GGAGCTGCAT GGCCAACGAG
    AAGTGCTCAC CCTCCGAGTA CTGGGATGAG GATGCTCCCG GGTGCAAGCC CTGCCATGTT
    AAGTGCTTCC ACTGCATGGG GCCGGCGGAG GACCAGTGTC AAACATGCCC CATGAACAGC
    CTTCTTCTCA ACACAACCTG TGTGAAGGAC TGCCCAGAGG GCTATTATGC CGATGAGGAC
    AGCAACCGGT GTGCCCACTG CCACAGCTCT TGCAGGACAT GTGAAGGGAG ACACAGCAGG
    CAGTGCCACT CCTGCCGACC GGGCTGGTTC CAGCTAGGAA AAGAGTGCCT GCTCCAGTGC
    AGGGAAGGAT ATTACGCAGA CAACTCCACT GGCCGGTGTG AGAGGTGCAA CAGGAGCTGC
    AAGGGGTGCC AGGGCCCACG GCCCACAGAC TGCCTGTCTT GCGATAGATT TTTCTTTCTG
    CTCCGCTCCA AAGGAGAGTG TCATCGCTCC TGCCCAGACC ATTACTATGT AGAGCAAAGC
    ACACAGACCT GTGAGAGATG CCATCCGACT TGTGATCAAT GCAAAGGAAA AGGAGCGTTG
    AATTGTTTAT CCTGTGTGTG GAGTTACCAC CTCATGGGAG GGATCTGCAC CTCGGACTGT
    CTTGTGGGGG AATACAGAGT GGGAGAGGGA GAGAAGTTTA ACTGTGAAAA ATGCCACGAG
    AGCTGCATGG AATGCAAGGG ACCAGGGGCC AAGAACTGCA CCTTGTGCCC TGCCAACCTG
    GTGCTGCACA TGGACGACAG CCACTGCCTC CACTGCTGCA ACACCTCTGA TCCCCCCAGT
    GCCCAGGAGT GCTGTGACTG CCAGGACACC ACGGACGAAT GCATCCTTCG AACAAGCAAG
    GTTAGGCCTG CAACTGAGCA TTTCAAGACA GCTCTGTTCA TCACCTCCTC CATGATGCTG
    GTGCTTCTGC TCGGGGCAGC TGTGGTAGTG TGGAAGAAAT CTCGTGGCCG AGTCCAGCCA
    GCAGCAAAGG CCGGCTATGA AAAACTGGCC GACCCCAACA AGTCTTACTC CTCCTATAAG
    AGCAGCTATA GAGAGAGCAC CAGCTTTGAA GAGGATCAGG TGATTGAGTA CAGGGATCGG
    GACTATGATG AGGATGATGA TGATGACATC GTCTACATGG GCCAGGATGG CACAGTCTAC
    CGGAAATTTA AATATGGGCT GCTGGATGAC GATGACATAG ATGAGCTGGA ATATGATGAC
    GAGAGTTACT CCTACTACCA GTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_005252096.1
    CDS582..6245
    Translation

    Target ORF information:

    RefSeq Version XM_005252039.3
    Organism Homo sapiens(human)
    Definition Homo sapiens proprotein convertase subtilisin/kexin type 5 (PCSK5), transcript variant X1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_005252039.3

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    4201
    4261
    4321
    4381
    4441
    4501
    4561
    4621
    4681
    4741
    4801
    4861
    4921
    4981
    5041
    5101
    5161
    5221
    5281
    5341
    5401
    5461
    5521
    5581
    5641
    ATGGGCTGGG GGAGCCGCTG CTGCTGCCCG GGACGTTTGG ACCTGCTGTG CGTGCTGGCG 
    CTGCTCGGGG GCTGCCTGCT CCCCGTGTGT CGGACGCGCG TCTACACCAA CCACTGGGCA
    GTCAAAATCG CCGGGGGCTT CCCGGAGGCC AACCGTATCG CCAGCAAGTA CGGATTCATC
    AACATAGGAC AGATAGGGGC CCTGAAGGAC TACTACCACT TCTACCATAG CAGGACGATT
    AAAAGGTCAG TTATCTCGAG CAGAGGGACC CACAGTTTCA TTTCAATGGA ACCAAAGGTG
    GAATGGATCC AACAGCAAGT GGTAAAAAAG CGGACAAAGA GGGATTATGA CTTCAGTCGT
    GCCCAGTCTA CCTATTTCAA TGATCCCAAG TGGCCCAGCA TGTGGTATAT GCACTGCAGT
    GACAATACAC ATCCCTGCCA GTCTGACATG AATATCGAAG GAGCCTGGAA GAGAGGCTAC
    ACGGGAAAGA ACATTGTGGT CACTATCCTG GATGACGGAA TTGAGAGAAC CCATCCAGAT
    CTGATGCAAA ACTACGATGC TCTGGCAAGT TGCGACGTGA ATGGGAATGA CTTGGACCCA
    ATGCCTCGTT ATGATGCAAG CAACGAGAAC AAGCATGGGA CTCGCTGTGC TGGAGAAGTG
    GCAGCCGCTG CAAACAATTC GCACTGCACA GTCGGAATTG CTTTCAACGC CAAGATCGGA
    GGAGTGCGAA TGCTGGACGG AGATGTCACG GACATGGTTG AAGCAAAATC AGTTAGCTTC
    AACCCCCAGC ACGTGCACAT TTACAGCGCC AGCTGGGGCC CGGATGATGA TGGCAAGACT
    GTGGACGGAC CAGCCCCCCT CACCCGGCAA GCCTTTGAAA ACGGCGTTAG AATGGGGCGG
    AGAGGCCTCG GCTCTGTGTT TGTTTGGGCA TCTGGAAATG GTGGAAGGAG CAAAGACCAC
    TGCTCCTGTG ATGGCTACAC CAACAGCATC TACACCATCT CCATCAGCAG CACTGCAGAA
    AGCGGAAAGA AACCTTGGTA CCTGGAAGAG TGTTCATCCA CGCTGGCCAC AACCTACAGC
    AGCGGGGAGT CCTACGATAA GAAAATCATC ACTACAGATC TGAGGCAGCG TTGCACGGAC
    AACCACACTG GGACGTCAGC CTCAGCCCCC ATGGCTGCAG GCATCATTGC GCTGGCCCTG
    GAAGCCAATC CGTTTCTGAC CTGGAGAGAC GTACAGCATG TTATTGTCAG GACTTCCCGT
    GCGGGACATT TGAACGCTAA TGACTGGAAA ACCAATGCTG CTGGTTTTAA GGTGAGCCAT
    CTTTATGGAT TTGGACTGAT GGACGCAGAA GCCATGGTGA TGGAGGCAGA GAAGTGGACC
    ACCGTTCCCC GGCAGCACGT GTGTGTGGAG AGCACAGACC GACAAATCAA GACAATCCGC
    CCTAACAGTG CAGTGCGCTC CATCTACAAA GCTTCAGGCT GCTCGGATAA CCCCAACCGC
    CATGTCAACT ACCTGGAGCA CGTCGTTGTG CGCATCACCA TCACCCACCC CAGGAGAGGA
    GACCTGGCCA TCTACCTGAC CTCGCCCTCT GGAACTAGGT CTCAGCTTTT GGCCAACAGG
    CTATTTGATC ACTCCATGGA AGGATTCAAA AACTGGGAGT TCATGACCAT TCATTGCTGG
    GGAGAAAGAG CTGCTGGTGA CTGGGTCCTT GAAGTTTATG ATACTCCCTC TCAGCTAAGG
    AACTTTAAGA CTCCAGGTAA ATTGAAAGAA TGGTCTTTGG TCCTCTACGG CACCTCCGTG
    CAGCCATATT CACCAACCAA TGAATTTCCG AAAGTGGAAC GGTTCCGCTA TAGCCGAGTT
    GAAGACCCCA CAGACGACTA TGGCACAGAG GATTATGCAG GTCCCTGCGA CCCTGAGTGC
    AGTGAGGTTG GCTGTGACGG GCCAGGACCA GACCACTGCA ATGACTGTTT GCACTACTAC
    TACAAGCTGA AAAACAATAC CAGGATCTGT GTCTCCAGCT GCCCCCCTGG CCACTACCAC
    GCCGACAAGA AGCGCTGCAG GAAGTGTGCC CCCAACTGTG AGTCCTGCTT TGGGAGCCAT
    GGTGACCAAT GCATGTCCTG CAAATATGGA TACTTTCTGA ATGAAGAAAC CAACAGCTGT
    GTTACTCACT GCCCTGATGG GTCATATCAG GATACCAAGA AAAATCTTTG CCGGAAATGC
    AGTGAAAACT GCAAGACATG TACTGAATTC CATAACTGTA CAGAATGTAG GGATGGGTTA
    AGCCTGCAGG GATCCCGGTG CTCTGTCTCC TGTGAAGATG GACGGTATTT CAACGGCCAG
    GACTGCCAGC CCTGCCACCG CTTCTGCGCC ACTTGTGCTG GGGCAGGAGC TGATGGGTGC
    ATTAACTGCA CAGAGGGCTA CTTCATGGAG GATGGGAGAT GCGTGCAGAG CTGTAGTATC
    AGCTATTACT TTGACCACTC TTCAGAGAAT GGATACAAAT CCTGCAAAAA ATGTGATATC
    AGTTGTTTGA CGTGCAATGG CCCAGGATTC AAGAACTGTA CAAGCTGCCC TAGTGGGTAT
    CTCTTAGACT TAGGAATGTG TCAAATGGGA GCCATTTGCA AGGATGGAGA ATATGTTGAT
    GAGCATGGCC ACTGCCAGAC CTGTGAGGCC TCATGTGCCA AGTGCCAGGG ACCAACCCAG
    GAAGACTGCA CTACCTGCCC CATGACAAGG ATTTTTGATG ATGGCCGCTG TGTTTCGAAC
    TGCCCCTCAT GGAAATTTGA ATTTGAGAAC CAATGCCATC CATGCCACCA CACCTGCCAG
    AGATGCCAAG GAAGTGGCCC TACCCACTGC ACCTCCTGTG GAGCAGACAA CTATGGCCGA
    GAGCACTTCC TGTACCAGGG AGAGTGTGGA GATAGCTGCC CAGAGGGCCA CTATGCCACT
    GAGGGGAACA CCTGCCTGCC CTGCCCAGAC AACTGTGAGC TTTGCCACAG CGTGCATGTC
    TGCACAAGAT GCATGAAGGG CTACTTCATA GCGCCCACCA ACCACACATG CCAGAAGTTA
    GAGTGTGGAC AAGGTGAAGT CCAAGACCCA GACTATGAAG AATGTGTCCC TTGTGAAGAA
    GGATGTCTGG GATGCAGCTT GGATGATCCA GGAACATGTA CATCTTGCGC TATGGGGTAT
    TACAGGTTTG ATCACCATTG TTATAAAACC TGTCCTGAGA AGACCTACAG TGAGGAAGTG
    GAATGCAAGG CGTGTGATAG TAACTGTGGC AGCTGTGACC AGAATGGGTG TTACTGGTGT
    GAAGAGGGCT TCTTTCTCTT AGGTGGCAGT TGTGTGAGGA AATGTGGTCC TGGATTCTAT
    GGTGACCAAG AAATGGGAGA ATGTGAGTCC TGCCACCGAG CATGCGAAAC CTGCACAGGC
    CCTGGTCATG ACGAGTGCAG CAGCTGCCAG GAAGGACTGC AGCTGCTGCG TGGGATGTGC
    GTGCATGCCA CCAAGACCCA GGAGGAGGGC AAATTCTGGA ATGAAGCTGT GTCCACTGCA
    AACCTATCTG TGGTGAAGAG CCTGCTGCAG GAGCGACGAA GGTGGAAAGT TCAAATCAAA
    AGAGATATTT TGAGAAAACT CCAGCCTTGT CATTCTTCTT GTAAAACCTG CAATGGATCT
    GCAACTCTGT GCACTTCATG TCCCAAAGGT GCATATCTTC TGGCTCAGGC CTGTGTTTCC
    TCCTGTCCCC AAGGCACATG GCCTTCCGTA AGGAGTGGGA GCTGCGAGAA CTGTACGGAG
    GCCTGTGCCA TCTGCTCTGG AGCCGATCTT TGCAAAAAAT GCCAGATGCA GCCGGGCCAC
    CCTCTCTTCC TCCATGAAGG CAGGTGCTAC TCCAAGTGCC CGGAGGGCTC TTATGCAGAA
    GACGGCATAT GTGAACGCTG TAGCTCTCCT TGCAGAACAT GTGAAGGAAA CGCCACCAAC
    TGCCATTCTT GTGAAGGAGG CCACGTCCTG CACCACGGAG TGTGCCAGGA AAACTGCCCC
    GAGAGGCACG TGGCTGTGAA GGGGGTATGC AAGCATTGCC CAGAGATGTG TCAGGACTGC
    ATCCATGAGA AAACATGCAA AGAGTGCACG CCTGAGTTCT TCCTGCACGA TGATATGTGC
    CACCAGTCCT GTCCCCGTGG CTTCTATGCA GACTCGCGCC ACTGTGTCCC CTGCCATAAA
    GACTGTCTGG AGTGCAGTGG CCCCAAAGCC GACGACTGCG AGCTCTGTCT TGAGAGTTCC
    TGGGTCCTCT ATGATGGACT GTGCTTGGAG GAGTGTCCAG CAGGAACCTA TTATGAAAAG
    GAGACTAAGG AGTGCAGAGA TTGCCACAAG TCCTGCTTGA CCTGCTCATC ATCTGGGACC
    TGCACCACCT GTCAGAAAGG CCTGATCATG AACCCTCGTG GGAGCTGCAT GGCCAACGAG
    AAGTGCTCAC CCTCCGAGTA CTGGGATGAG GATGCTCCCG GGTGCAAGCC CTGCCATGTT
    AAGTGCTTCC ACTGCATGGG GCCGGCGGAG GACCAGTGTC AAACATGCCC CATGAACAGC
    CTTCTTCTCA ACACAACCTG TGTGAAGGAC TGCCCAGAGG GCTATTATGC CGATGAGGAC
    AGCAACCGGT GTGCCCACTG CCACAGCTCT TGCAGGACAT GTGAAGGGAG ACACAGCAGG
    CAGTGCCACT CCTGCCGACC GGGCTGGTTC CAGCTAGGAA AAGAGTGCCT GCTCCAGTGC
    AGGGAAGGAT ATTACGCAGA CAACTCCACT GGCCGGTGTG AGAGGTGCAA CAGGAGCTGC
    AAGGGGTGCC AGGGCCCACG GCCCACAGAC TGCCTGTCTT GCGATAGATT TTTCTTTCTG
    CTCCGCTCCA AAGGAGAGTG TCATCGCTCC TGCCCAGACC ATTACTATGT AGAGCAAAGC
    ACACAGACCT GTGAGAGATG CCATCCGACT TGTGATCAAT GCAAAGGAAA AGGAGCGTTG
    AATTGTTTAT CCTGTGTGTG GAGTTACCAC CTCATGGGAG GGATCTGCAC CTCGGACTGT
    CTTGTGGGGG AATACAGAGT GGGAGAGGGA GAGAAGTTTA ACTGTGAAAA ATGCCACGAG
    AGCTGCATGG AATGCAAGGG ACCAGGGGCC AAGAACTGCA CCTTGTGCCC TGCCAACCTG
    GTGCTGCACA TGGACGACAG CCACTGCCTC CACTGCTGCA ACACCTCTGA TCCCCCCAGT
    GCCCAGGAGT GCTGTGACTG CCAGGACACC ACGGACGAAT GCATCCTTCG AACAAGCAAG
    GTTAGGCCTG CAACTGAGCA TTTCAAGACA GCTCTGTTCA TCACCTCCTC CATGATGCTG
    GTGCTTCTGC TCGGGGCAGC TGTGGTAGTG TGGAAGAAAT CTCGTGGCCG AGTCCAGCCA
    GCAGCAAAGG CCGGCTATGA AAAACTGGCC GACCCCAACA AGTCTTACTC CTCCTATAAG
    AGCAGCTATA GAGAGAGCAC CAGCTTTGAA GAGGATCAGG TGATTGAGTA CAGGGATCGG
    GACTATGATG AGGATGATGA TGATGACATC GTCTACATGG GCCAGGATGG CACAGTCTAC
    CGGAAATTTA AATATGGGCT GCTGGATGAC GATGACATAG ATGAGCTGGA ATATGATGAC
    GAGAGTTACT CCTACTACCA GTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu43330
    Clone ID Related Accession (Same CDS sequence) XM_005252039.3 , NM_001372043.1 , XM_005252039.4
    Accession Version XM_005252039.4 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 5664bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-06-12
    Organism Homo sapiens(human)
    Product proprotein convertase subtilisin/kexin type 5 isoform X1
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005252039.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20190607 Annotation Version :: 109.20190607 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Freeze :: 20190607 ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    4201
    4261
    4321
    4381
    4441
    4501
    4561
    4621
    4681
    4741
    4801
    4861
    4921
    4981
    5041
    5101
    5161
    5221
    5281
    5341
    5401
    5461
    5521
    5581
    5641
    ATGGGCTGGG GGAGCCGCTG CTGCTGCCCG GGACGTTTGG ACCTGCTGTG CGTGCTGGCG 
    CTGCTCGGGG GCTGCCTGCT CCCCGTGTGT CGGACGCGCG TCTACACCAA CCACTGGGCA
    GTCAAAATCG CCGGGGGCTT CCCGGAGGCC AACCGTATCG CCAGCAAGTA CGGATTCATC
    AACATAGGAC AGATAGGGGC CCTGAAGGAC TACTACCACT TCTACCATAG CAGGACGATT
    AAAAGGTCAG TTATCTCGAG CAGAGGGACC CACAGTTTCA TTTCAATGGA ACCAAAGGTG
    GAATGGATCC AACAGCAAGT GGTAAAAAAG CGGACAAAGA GGGATTATGA CTTCAGTCGT
    GCCCAGTCTA CCTATTTCAA TGATCCCAAG TGGCCCAGCA TGTGGTATAT GCACTGCAGT
    GACAATACAC ATCCCTGCCA GTCTGACATG AATATCGAAG GAGCCTGGAA GAGAGGCTAC
    ACGGGAAAGA ACATTGTGGT CACTATCCTG GATGACGGAA TTGAGAGAAC CCATCCAGAT
    CTGATGCAAA ACTACGATGC TCTGGCAAGT TGCGACGTGA ATGGGAATGA CTTGGACCCA
    ATGCCTCGTT ATGATGCAAG CAACGAGAAC AAGCATGGGA CTCGCTGTGC TGGAGAAGTG
    GCAGCCGCTG CAAACAATTC GCACTGCACA GTCGGAATTG CTTTCAACGC CAAGATCGGA
    GGAGTGCGAA TGCTGGACGG AGATGTCACG GACATGGTTG AAGCAAAATC AGTTAGCTTC
    AACCCCCAGC ACGTGCACAT TTACAGCGCC AGCTGGGGCC CGGATGATGA TGGCAAGACT
    GTGGACGGAC CAGCCCCCCT CACCCGGCAA GCCTTTGAAA ACGGCGTTAG AATGGGGCGG
    AGAGGCCTCG GCTCTGTGTT TGTTTGGGCA TCTGGAAATG GTGGAAGGAG CAAAGACCAC
    TGCTCCTGTG ATGGCTACAC CAACAGCATC TACACCATCT CCATCAGCAG CACTGCAGAA
    AGCGGAAAGA AACCTTGGTA CCTGGAAGAG TGTTCATCCA CGCTGGCCAC AACCTACAGC
    AGCGGGGAGT CCTACGATAA GAAAATCATC ACTACAGATC TGAGGCAGCG TTGCACGGAC
    AACCACACTG GGACGTCAGC CTCAGCCCCC ATGGCTGCAG GCATCATTGC GCTGGCCCTG
    GAAGCCAATC CGTTTCTGAC CTGGAGAGAC GTACAGCATG TTATTGTCAG GACTTCCCGT
    GCGGGACATT TGAACGCTAA TGACTGGAAA ACCAATGCTG CTGGTTTTAA GGTGAGCCAT
    CTTTATGGAT TTGGACTGAT GGACGCAGAA GCCATGGTGA TGGAGGCAGA GAAGTGGACC
    ACCGTTCCCC GGCAGCACGT GTGTGTGGAG AGCACAGACC GACAAATCAA GACAATCCGC
    CCTAACAGTG CAGTGCGCTC CATCTACAAA GCTTCAGGCT GCTCGGATAA CCCCAACCGC
    CATGTCAACT ACCTGGAGCA CGTCGTTGTG CGCATCACCA TCACCCACCC CAGGAGAGGA
    GACCTGGCCA TCTACCTGAC CTCGCCCTCT GGAACTAGGT CTCAGCTTTT GGCCAACAGG
    CTATTTGATC ACTCCATGGA AGGATTCAAA AACTGGGAGT TCATGACCAT TCATTGCTGG
    GGAGAAAGAG CTGCTGGTGA CTGGGTCCTT GAAGTTTATG ATACTCCCTC TCAGCTAAGG
    AACTTTAAGA CTCCAGGTAA ATTGAAAGAA TGGTCTTTGG TCCTCTACGG CACCTCCGTG
    CAGCCATATT CACCAACCAA TGAATTTCCG AAAGTGGAAC GGTTCCGCTA TAGCCGAGTT
    GAAGACCCCA CAGACGACTA TGGCACAGAG GATTATGCAG GTCCCTGCGA CCCTGAGTGC
    AGTGAGGTTG GCTGTGACGG GCCAGGACCA GACCACTGCA ATGACTGTTT GCACTACTAC
    TACAAGCTGA AAAACAATAC CAGGATCTGT GTCTCCAGCT GCCCCCCTGG CCACTACCAC
    GCCGACAAGA AGCGCTGCAG GAAGTGTGCC CCCAACTGTG AGTCCTGCTT TGGGAGCCAT
    GGTGACCAAT GCATGTCCTG CAAATATGGA TACTTTCTGA ATGAAGAAAC CAACAGCTGT
    GTTACTCACT GCCCTGATGG GTCATATCAG GATACCAAGA AAAATCTTTG CCGGAAATGC
    AGTGAAAACT GCAAGACATG TACTGAATTC CATAACTGTA CAGAATGTAG GGATGGGTTA
    AGCCTGCAGG GATCCCGGTG CTCTGTCTCC TGTGAAGATG GACGGTATTT CAACGGCCAG
    GACTGCCAGC CCTGCCACCG CTTCTGCGCC ACTTGTGCTG GGGCAGGAGC TGATGGGTGC
    ATTAACTGCA CAGAGGGCTA CTTCATGGAG GATGGGAGAT GCGTGCAGAG CTGTAGTATC
    AGCTATTACT TTGACCACTC TTCAGAGAAT GGATACAAAT CCTGCAAAAA ATGTGATATC
    AGTTGTTTGA CGTGCAATGG CCCAGGATTC AAGAACTGTA CAAGCTGCCC TAGTGGGTAT
    CTCTTAGACT TAGGAATGTG TCAAATGGGA GCCATTTGCA AGGATGGAGA ATATGTTGAT
    GAGCATGGCC ACTGCCAGAC CTGTGAGGCC TCATGTGCCA AGTGCCAGGG ACCAACCCAG
    GAAGACTGCA CTACCTGCCC CATGACAAGG ATTTTTGATG ATGGCCGCTG TGTTTCGAAC
    TGCCCCTCAT GGAAATTTGA ATTTGAGAAC CAATGCCATC CATGCCACCA CACCTGCCAG
    AGATGCCAAG GAAGTGGCCC TACCCACTGC ACCTCCTGTG GAGCAGACAA CTATGGCCGA
    GAGCACTTCC TGTACCAGGG AGAGTGTGGA GATAGCTGCC CAGAGGGCCA CTATGCCACT
    GAGGGGAACA CCTGCCTGCC CTGCCCAGAC AACTGTGAGC TTTGCCACAG CGTGCATGTC
    TGCACAAGAT GCATGAAGGG CTACTTCATA GCGCCCACCA ACCACACATG CCAGAAGTTA
    GAGTGTGGAC AAGGTGAAGT CCAAGACCCA GACTATGAAG AATGTGTCCC TTGTGAAGAA
    GGATGTCTGG GATGCAGCTT GGATGATCCA GGAACATGTA CATCTTGCGC TATGGGGTAT
    TACAGGTTTG ATCACCATTG TTATAAAACC TGTCCTGAGA AGACCTACAG TGAGGAAGTG
    GAATGCAAGG CGTGTGATAG TAACTGTGGC AGCTGTGACC AGAATGGGTG TTACTGGTGT
    GAAGAGGGCT TCTTTCTCTT AGGTGGCAGT TGTGTGAGGA AATGTGGTCC TGGATTCTAT
    GGTGACCAAG AAATGGGAGA ATGTGAGTCC TGCCACCGAG CATGCGAAAC CTGCACAGGC
    CCTGGTCATG ACGAGTGCAG CAGCTGCCAG GAAGGACTGC AGCTGCTGCG TGGGATGTGC
    GTGCATGCCA CCAAGACCCA GGAGGAGGGC AAATTCTGGA ATGAAGCTGT GTCCACTGCA
    AACCTATCTG TGGTGAAGAG CCTGCTGCAG GAGCGACGAA GGTGGAAAGT TCAAATCAAA
    AGAGATATTT TGAGAAAACT CCAGCCTTGT CATTCTTCTT GTAAAACCTG CAATGGATCT
    GCAACTCTGT GCACTTCATG TCCCAAAGGT GCATATCTTC TGGCTCAGGC CTGTGTTTCC
    TCCTGTCCCC AAGGCACATG GCCTTCCGTA AGGAGTGGGA GCTGCGAGAA CTGTACGGAG
    GCCTGTGCCA TCTGCTCTGG AGCCGATCTT TGCAAAAAAT GCCAGATGCA GCCGGGCCAC
    CCTCTCTTCC TCCATGAAGG CAGGTGCTAC TCCAAGTGCC CGGAGGGCTC TTATGCAGAA
    GACGGCATAT GTGAACGCTG TAGCTCTCCT TGCAGAACAT GTGAAGGAAA CGCCACCAAC
    TGCCATTCTT GTGAAGGAGG CCACGTCCTG CACCACGGAG TGTGCCAGGA AAACTGCCCC
    GAGAGGCACG TGGCTGTGAA GGGGGTATGC AAGCATTGCC CAGAGATGTG TCAGGACTGC
    ATCCATGAGA AAACATGCAA AGAGTGCACG CCTGAGTTCT TCCTGCACGA TGATATGTGC
    CACCAGTCCT GTCCCCGTGG CTTCTATGCA GACTCGCGCC ACTGTGTCCC CTGCCATAAA
    GACTGTCTGG AGTGCAGTGG CCCCAAAGCC GACGACTGCG AGCTCTGTCT TGAGAGTTCC
    TGGGTCCTCT ATGATGGACT GTGCTTGGAG GAGTGTCCAG CAGGAACCTA TTATGAAAAG
    GAGACTAAGG AGTGCAGAGA TTGCCACAAG TCCTGCTTGA CCTGCTCATC ATCTGGGACC
    TGCACCACCT GTCAGAAAGG CCTGATCATG AACCCTCGTG GGAGCTGCAT GGCCAACGAG
    AAGTGCTCAC CCTCCGAGTA CTGGGATGAG GATGCTCCCG GGTGCAAGCC CTGCCATGTT
    AAGTGCTTCC ACTGCATGGG GCCGGCGGAG GACCAGTGTC AAACATGCCC CATGAACAGC
    CTTCTTCTCA ACACAACCTG TGTGAAGGAC TGCCCAGAGG GCTATTATGC CGATGAGGAC
    AGCAACCGGT GTGCCCACTG CCACAGCTCT TGCAGGACAT GTGAAGGGAG ACACAGCAGG
    CAGTGCCACT CCTGCCGACC GGGCTGGTTC CAGCTAGGAA AAGAGTGCCT GCTCCAGTGC
    AGGGAAGGAT ATTACGCAGA CAACTCCACT GGCCGGTGTG AGAGGTGCAA CAGGAGCTGC
    AAGGGGTGCC AGGGCCCACG GCCCACAGAC TGCCTGTCTT GCGATAGATT TTTCTTTCTG
    CTCCGCTCCA AAGGAGAGTG TCATCGCTCC TGCCCAGACC ATTACTATGT AGAGCAAAGC
    ACACAGACCT GTGAGAGATG CCATCCGACT TGTGATCAAT GCAAAGGAAA AGGAGCGTTG
    AATTGTTTAT CCTGTGTGTG GAGTTACCAC CTCATGGGAG GGATCTGCAC CTCGGACTGT
    CTTGTGGGGG AATACAGAGT GGGAGAGGGA GAGAAGTTTA ACTGTGAAAA ATGCCACGAG
    AGCTGCATGG AATGCAAGGG ACCAGGGGCC AAGAACTGCA CCTTGTGCCC TGCCAACCTG
    GTGCTGCACA TGGACGACAG CCACTGCCTC CACTGCTGCA ACACCTCTGA TCCCCCCAGT
    GCCCAGGAGT GCTGTGACTG CCAGGACACC ACGGACGAAT GCATCCTTCG AACAAGCAAG
    GTTAGGCCTG CAACTGAGCA TTTCAAGACA GCTCTGTTCA TCACCTCCTC CATGATGCTG
    GTGCTTCTGC TCGGGGCAGC TGTGGTAGTG TGGAAGAAAT CTCGTGGCCG AGTCCAGCCA
    GCAGCAAAGG CCGGCTATGA AAAACTGGCC GACCCCAACA AGTCTTACTC CTCCTATAAG
    AGCAGCTATA GAGAGAGCAC CAGCTTTGAA GAGGATCAGG TGATTGAGTA CAGGGATCGG
    GACTATGATG AGGATGATGA TGATGACATC GTCTACATGG GCCAGGATGG CACAGTCTAC
    CGGAAATTTA AATATGGGCT GCTGGATGAC GATGACATAG ATGAGCTGGA ATATGATGAC
    GAGAGTTACT CCTACTACCA GTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_005252096.1
    CDS537..6200
    Translation

    Target ORF information:

    RefSeq Version XM_005252039.4
    Organism Homo sapiens(human)
    Definition Homo sapiens proprotein convertase subtilisin/kexin type 5 (PCSK5), transcript variant X1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_005252039.4

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    4201
    4261
    4321
    4381
    4441
    4501
    4561
    4621
    4681
    4741
    4801
    4861
    4921
    4981
    5041
    5101
    5161
    5221
    5281
    5341
    5401
    5461
    5521
    5581
    5641
    ATGGGCTGGG GGAGCCGCTG CTGCTGCCCG GGACGTTTGG ACCTGCTGTG CGTGCTGGCG 
    CTGCTCGGGG GCTGCCTGCT CCCCGTGTGT CGGACGCGCG TCTACACCAA CCACTGGGCA
    GTCAAAATCG CCGGGGGCTT CCCGGAGGCC AACCGTATCG CCAGCAAGTA CGGATTCATC
    AACATAGGAC AGATAGGGGC CCTGAAGGAC TACTACCACT TCTACCATAG CAGGACGATT
    AAAAGGTCAG TTATCTCGAG CAGAGGGACC CACAGTTTCA TTTCAATGGA ACCAAAGGTG
    GAATGGATCC AACAGCAAGT GGTAAAAAAG CGGACAAAGA GGGATTATGA CTTCAGTCGT
    GCCCAGTCTA CCTATTTCAA TGATCCCAAG TGGCCCAGCA TGTGGTATAT GCACTGCAGT
    GACAATACAC ATCCCTGCCA GTCTGACATG AATATCGAAG GAGCCTGGAA GAGAGGCTAC
    ACGGGAAAGA ACATTGTGGT CACTATCCTG GATGACGGAA TTGAGAGAAC CCATCCAGAT
    CTGATGCAAA ACTACGATGC TCTGGCAAGT TGCGACGTGA ATGGGAATGA CTTGGACCCA
    ATGCCTCGTT ATGATGCAAG CAACGAGAAC AAGCATGGGA CTCGCTGTGC TGGAGAAGTG
    GCAGCCGCTG CAAACAATTC GCACTGCACA GTCGGAATTG CTTTCAACGC CAAGATCGGA
    GGAGTGCGAA TGCTGGACGG AGATGTCACG GACATGGTTG AAGCAAAATC AGTTAGCTTC
    AACCCCCAGC ACGTGCACAT TTACAGCGCC AGCTGGGGCC CGGATGATGA TGGCAAGACT
    GTGGACGGAC CAGCCCCCCT CACCCGGCAA GCCTTTGAAA ACGGCGTTAG AATGGGGCGG
    AGAGGCCTCG GCTCTGTGTT TGTTTGGGCA TCTGGAAATG GTGGAAGGAG CAAAGACCAC
    TGCTCCTGTG ATGGCTACAC CAACAGCATC TACACCATCT CCATCAGCAG CACTGCAGAA
    AGCGGAAAGA AACCTTGGTA CCTGGAAGAG TGTTCATCCA CGCTGGCCAC AACCTACAGC
    AGCGGGGAGT CCTACGATAA GAAAATCATC ACTACAGATC TGAGGCAGCG TTGCACGGAC
    AACCACACTG GGACGTCAGC CTCAGCCCCC ATGGCTGCAG GCATCATTGC GCTGGCCCTG
    GAAGCCAATC CGTTTCTGAC CTGGAGAGAC GTACAGCATG TTATTGTCAG GACTTCCCGT
    GCGGGACATT TGAACGCTAA TGACTGGAAA ACCAATGCTG CTGGTTTTAA GGTGAGCCAT
    CTTTATGGAT TTGGACTGAT GGACGCAGAA GCCATGGTGA TGGAGGCAGA GAAGTGGACC
    ACCGTTCCCC GGCAGCACGT GTGTGTGGAG AGCACAGACC GACAAATCAA GACAATCCGC
    CCTAACAGTG CAGTGCGCTC CATCTACAAA GCTTCAGGCT GCTCGGATAA CCCCAACCGC
    CATGTCAACT ACCTGGAGCA CGTCGTTGTG CGCATCACCA TCACCCACCC CAGGAGAGGA
    GACCTGGCCA TCTACCTGAC CTCGCCCTCT GGAACTAGGT CTCAGCTTTT GGCCAACAGG
    CTATTTGATC ACTCCATGGA AGGATTCAAA AACTGGGAGT TCATGACCAT TCATTGCTGG
    GGAGAAAGAG CTGCTGGTGA CTGGGTCCTT GAAGTTTATG ATACTCCCTC TCAGCTAAGG
    AACTTTAAGA CTCCAGGTAA ATTGAAAGAA TGGTCTTTGG TCCTCTACGG CACCTCCGTG
    CAGCCATATT CACCAACCAA TGAATTTCCG AAAGTGGAAC GGTTCCGCTA TAGCCGAGTT
    GAAGACCCCA CAGACGACTA TGGCACAGAG GATTATGCAG GTCCCTGCGA CCCTGAGTGC
    AGTGAGGTTG GCTGTGACGG GCCAGGACCA GACCACTGCA ATGACTGTTT GCACTACTAC
    TACAAGCTGA AAAACAATAC CAGGATCTGT GTCTCCAGCT GCCCCCCTGG CCACTACCAC
    GCCGACAAGA AGCGCTGCAG GAAGTGTGCC CCCAACTGTG AGTCCTGCTT TGGGAGCCAT
    GGTGACCAAT GCATGTCCTG CAAATATGGA TACTTTCTGA ATGAAGAAAC CAACAGCTGT
    GTTACTCACT GCCCTGATGG GTCATATCAG GATACCAAGA AAAATCTTTG CCGGAAATGC
    AGTGAAAACT GCAAGACATG TACTGAATTC CATAACTGTA CAGAATGTAG GGATGGGTTA
    AGCCTGCAGG GATCCCGGTG CTCTGTCTCC TGTGAAGATG GACGGTATTT CAACGGCCAG
    GACTGCCAGC CCTGCCACCG CTTCTGCGCC ACTTGTGCTG GGGCAGGAGC TGATGGGTGC
    ATTAACTGCA CAGAGGGCTA CTTCATGGAG GATGGGAGAT GCGTGCAGAG CTGTAGTATC
    AGCTATTACT TTGACCACTC TTCAGAGAAT GGATACAAAT CCTGCAAAAA ATGTGATATC
    AGTTGTTTGA CGTGCAATGG CCCAGGATTC AAGAACTGTA CAAGCTGCCC TAGTGGGTAT
    CTCTTAGACT TAGGAATGTG TCAAATGGGA GCCATTTGCA AGGATGGAGA ATATGTTGAT
    GAGCATGGCC ACTGCCAGAC CTGTGAGGCC TCATGTGCCA AGTGCCAGGG ACCAACCCAG
    GAAGACTGCA CTACCTGCCC CATGACAAGG ATTTTTGATG ATGGCCGCTG TGTTTCGAAC
    TGCCCCTCAT GGAAATTTGA ATTTGAGAAC CAATGCCATC CATGCCACCA CACCTGCCAG
    AGATGCCAAG GAAGTGGCCC TACCCACTGC ACCTCCTGTG GAGCAGACAA CTATGGCCGA
    GAGCACTTCC TGTACCAGGG AGAGTGTGGA GATAGCTGCC CAGAGGGCCA CTATGCCACT
    GAGGGGAACA CCTGCCTGCC CTGCCCAGAC AACTGTGAGC TTTGCCACAG CGTGCATGTC
    TGCACAAGAT GCATGAAGGG CTACTTCATA GCGCCCACCA ACCACACATG CCAGAAGTTA
    GAGTGTGGAC AAGGTGAAGT CCAAGACCCA GACTATGAAG AATGTGTCCC TTGTGAAGAA
    GGATGTCTGG GATGCAGCTT GGATGATCCA GGAACATGTA CATCTTGCGC TATGGGGTAT
    TACAGGTTTG ATCACCATTG TTATAAAACC TGTCCTGAGA AGACCTACAG TGAGGAAGTG
    GAATGCAAGG CGTGTGATAG TAACTGTGGC AGCTGTGACC AGAATGGGTG TTACTGGTGT
    GAAGAGGGCT TCTTTCTCTT AGGTGGCAGT TGTGTGAGGA AATGTGGTCC TGGATTCTAT
    GGTGACCAAG AAATGGGAGA ATGTGAGTCC TGCCACCGAG CATGCGAAAC CTGCACAGGC
    CCTGGTCATG ACGAGTGCAG CAGCTGCCAG GAAGGACTGC AGCTGCTGCG TGGGATGTGC
    GTGCATGCCA CCAAGACCCA GGAGGAGGGC AAATTCTGGA ATGAAGCTGT GTCCACTGCA
    AACCTATCTG TGGTGAAGAG CCTGCTGCAG GAGCGACGAA GGTGGAAAGT TCAAATCAAA
    AGAGATATTT TGAGAAAACT CCAGCCTTGT CATTCTTCTT GTAAAACCTG CAATGGATCT
    GCAACTCTGT GCACTTCATG TCCCAAAGGT GCATATCTTC TGGCTCAGGC CTGTGTTTCC
    TCCTGTCCCC AAGGCACATG GCCTTCCGTA AGGAGTGGGA GCTGCGAGAA CTGTACGGAG
    GCCTGTGCCA TCTGCTCTGG AGCCGATCTT TGCAAAAAAT GCCAGATGCA GCCGGGCCAC
    CCTCTCTTCC TCCATGAAGG CAGGTGCTAC TCCAAGTGCC CGGAGGGCTC TTATGCAGAA
    GACGGCATAT GTGAACGCTG TAGCTCTCCT TGCAGAACAT GTGAAGGAAA CGCCACCAAC
    TGCCATTCTT GTGAAGGAGG CCACGTCCTG CACCACGGAG TGTGCCAGGA AAACTGCCCC
    GAGAGGCACG TGGCTGTGAA GGGGGTATGC AAGCATTGCC CAGAGATGTG TCAGGACTGC
    ATCCATGAGA AAACATGCAA AGAGTGCACG CCTGAGTTCT TCCTGCACGA TGATATGTGC
    CACCAGTCCT GTCCCCGTGG CTTCTATGCA GACTCGCGCC ACTGTGTCCC CTGCCATAAA
    GACTGTCTGG AGTGCAGTGG CCCCAAAGCC GACGACTGCG AGCTCTGTCT TGAGAGTTCC
    TGGGTCCTCT ATGATGGACT GTGCTTGGAG GAGTGTCCAG CAGGAACCTA TTATGAAAAG
    GAGACTAAGG AGTGCAGAGA TTGCCACAAG TCCTGCTTGA CCTGCTCATC ATCTGGGACC
    TGCACCACCT GTCAGAAAGG CCTGATCATG AACCCTCGTG GGAGCTGCAT GGCCAACGAG
    AAGTGCTCAC CCTCCGAGTA CTGGGATGAG GATGCTCCCG GGTGCAAGCC CTGCCATGTT
    AAGTGCTTCC ACTGCATGGG GCCGGCGGAG GACCAGTGTC AAACATGCCC CATGAACAGC
    CTTCTTCTCA ACACAACCTG TGTGAAGGAC TGCCCAGAGG GCTATTATGC CGATGAGGAC
    AGCAACCGGT GTGCCCACTG CCACAGCTCT TGCAGGACAT GTGAAGGGAG ACACAGCAGG
    CAGTGCCACT CCTGCCGACC GGGCTGGTTC CAGCTAGGAA AAGAGTGCCT GCTCCAGTGC
    AGGGAAGGAT ATTACGCAGA CAACTCCACT GGCCGGTGTG AGAGGTGCAA CAGGAGCTGC
    AAGGGGTGCC AGGGCCCACG GCCCACAGAC TGCCTGTCTT GCGATAGATT TTTCTTTCTG
    CTCCGCTCCA AAGGAGAGTG TCATCGCTCC TGCCCAGACC ATTACTATGT AGAGCAAAGC
    ACACAGACCT GTGAGAGATG CCATCCGACT TGTGATCAAT GCAAAGGAAA AGGAGCGTTG
    AATTGTTTAT CCTGTGTGTG GAGTTACCAC CTCATGGGAG GGATCTGCAC CTCGGACTGT
    CTTGTGGGGG AATACAGAGT GGGAGAGGGA GAGAAGTTTA ACTGTGAAAA ATGCCACGAG
    AGCTGCATGG AATGCAAGGG ACCAGGGGCC AAGAACTGCA CCTTGTGCCC TGCCAACCTG
    GTGCTGCACA TGGACGACAG CCACTGCCTC CACTGCTGCA ACACCTCTGA TCCCCCCAGT
    GCCCAGGAGT GCTGTGACTG CCAGGACACC ACGGACGAAT GCATCCTTCG AACAAGCAAG
    GTTAGGCCTG CAACTGAGCA TTTCAAGACA GCTCTGTTCA TCACCTCCTC CATGATGCTG
    GTGCTTCTGC TCGGGGCAGC TGTGGTAGTG TGGAAGAAAT CTCGTGGCCG AGTCCAGCCA
    GCAGCAAAGG CCGGCTATGA AAAACTGGCC GACCCCAACA AGTCTTACTC CTCCTATAAG
    AGCAGCTATA GAGAGAGCAC CAGCTTTGAA GAGGATCAGG TGATTGAGTA CAGGGATCGG
    GACTATGATG AGGATGATGA TGATGACATC GTCTACATGG GCCAGGATGG CACAGTCTAC
    CGGAAATTTA AATATGGGCT GCTGGATGAC GATGACATAG ATGAGCTGGA ATATGATGAC
    GAGAGTTACT CCTACTACCA GTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu59541
    Clone ID Related Accession (Same CDS sequence) XM_011518769.3 , XM_011518769.2
    Accession Version XM_011518769.3 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 5661bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-05
    Organism Homo sapiens(human)
    Product proprotein convertase subtilisin/kexin type 5 isoform X2
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011518769.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    4201
    4261
    4321
    4381
    4441
    4501
    4561
    4621
    4681
    4741
    4801
    4861
    4921
    4981
    5041
    5101
    5161
    5221
    5281
    5341
    5401
    5461
    5521
    5581
    5641
    ATGGGCTGGG GGAGCCGCTG CTGCTGCCCG GGACGTTTGG ACCTGCTGTG CGTGCTGGCG 
    CTGCTCGGGG GCTGCCTGCT CCCCGTGTGT CGGACGCGCG TCTACACCAA CCACTGGGCA
    GTCAAAATCG CCGGGGGCTT CCCGGAGGCC AACCGTATCG CCAGCAAGTA CGGATTCATC
    AACATAGGAC AGATAGGGGC CCTGAAGGAC TACTACCACT TCTACCATAG CAGGACGATT
    AAAAGGTCAG TTATCTCGAG CAGAGGGACC CACAGTTTCA TTTCAATGGA ACCAAAGGTG
    GAATGGATCC AACAGCAAGT GGTAAAAAAG CGGACAAAGA GGGATTATGA CTTCAGTCGT
    GCCCAGTCTA CCTATTTCAA TGATCCCAAG TGGCCCAGCA TGTGGTATAT GCACTGCAGT
    GACAATACAC ATCCCTGCCA GTCTGACATG AATATCGAAG GAGCCTGGAA GAGAGGCTAC
    ACGGGAAAGA ACATTGTGGT CACTATCCTG GATGACGGAA TTGAGAGAAC CCATCCAGAT
    CTGATGCAAA ACTACGATGC TCTGGCAAGT TGCGACGTGA ATGGGAATGA CTTGGACCCA
    ATGCCTCGTT ATGATGCAAG CAACGAGAAC AAGCATGGGA CTCGCTGTGC TGGAGAAGTG
    GCAGCCGCTG CAAACAATTC GCACTGCACA GTCGGAATTG CTTTCAACGC CAAGATCGGA
    GGAGTGCGAA TGCTGGACGG AGATGTCACG GACATGGTTG AAGCAAAATC AGTTAGCTTC
    AACCCCCAGC ACGTGCACAT TTACAGCGCC AGCTGGGGCC CGGATGATGA TGGCAAGACT
    GTGGACGGAC CAGCCCCCCT CACCCGGCAA GCCTTTGAAA ACGGCGTTAG AATGGGGCGG
    AGAGGCCTCG GCTCTGTGTT TGTTTGGGCA TCTGGAAATG GTGGAAGGAG CAAAGACCAC
    TGCTCCTGTG ATGGCTACAC CAACAGCATC TACACCATCT CCATCAGCAG CACTGCAGAA
    AGCGGAAAGA AACCTTGGTA CCTGGAAGAG TGTTCATCCA CGCTGGCCAC AACCTACAGC
    AGCGGGGAGT CCTACGATAA GAAAATCATC ACTACAGATC TGAGGCAGCG TTGCACGGAC
    AACCACACTG GGACGTCAGC CTCAGCCCCC ATGGCTGCAG GCATCATTGC GCTGGCCCTG
    GAAGCCAATC CGTTTCTGAC CTGGAGAGAC GTACAGCATG TTATTGTCAG GACTTCCCGT
    GCGGGACATT TGAACGCTAA TGACTGGAAA ACCAATGCTG CTGGTTTTAA GGTGAGCCAT
    CTTTATGGAT TTGGACTGAT GGACGCAGAA GCCATGGTGA TGGAGGCAGA GAAGTGGACC
    ACCGTTCCCC GGCAGCACGT GTGTGTGGAG AGCACAGACC GACAAATCAA GACAATCCGC
    CCTAACAGTG CAGTGCGCTC CATCTACAAA GCTTCAGGCT GCTCGGATAA CCCCAACCGC
    CATGTCAACT ACCTGGAGCA CGTCGTTGTG CGCATCACCA TCACCCACCC CAGGAGAGGA
    GACCTGGCCA TCTACCTGAC CTCGCCCTCT GGAACTAGGT CTCAGCTTTT GGCCAACAGG
    CTATTTGATC ACTCCATGGA AGGATTCAAA AACTGGGAGT TCATGACCAT TCATTGCTGG
    GGAGAAAGAG CTGCTGGTGA CTGGGTCCTT GAAGTTTATG ATACTCCCTC TCAGCTAAGG
    AACTTTAAGA CTCCAGGTAA ATTGAAAGAA TGGTCTTTGG TCCTCTACGG CACCTCCGTG
    CAGCCATATT CACCAACCAA TGAATTTCCG AAAGTGGAAC GGTTCCGCTA TAGCCGAGTT
    GAAGACCCCA CAGACGACTA TGGCACAGAG GATTATGCAG GTCCCTGCGA CCCTGAGTGC
    AGTGAGGTTG GCTGTGACGG GCCAGGACCA GACCACTGCA ATGACTGTTT GCACTACTAC
    TACAAGCTGA AAAACAATAC CAGGATCTGT GTCTCCAGCT GCCCCCCTGG CCACTACCAC
    GCCGACAAGA AGCGCTGCAG GAAGTGTGCC CCCAACTGTG AGTCCTGCTT TGGGAGCCAT
    GGTGACCAAT GCATGTCCTG CAAATATGGA TACTTTCTGA ATGAAGAAAC CAACAGCTGT
    GTTACTCACT GCCCTGATGG GTCATATCAG GATACCAAGA AAAATCTTTG CCGGAAATGC
    AGTGAAAACT GCAAGACATG TACTGAATTC CATAACTGTA CAGAATGTAG GGATGGGTTA
    AGCCTGCAGG GATCCCGGTG CTCTGTCTCC TGTGAAGATG GACGGTATTT CAACGGCCAG
    GACTGCCAGC CCTGCCACCG CTTCTGCGCC ACTTGTGCTG GGGCAGGAGC TGATGGGTGC
    ATTAACTGCA CAGAGGGCTA CTTCATGGAG GATGGGAGAT GCGTGCAGAG CTGTAGTATC
    AGCTATTACT TTGACCACTC TTCAGAGAAT GGATACAAAT CCTGCAAAAA ATGTGATATC
    AGTTGTTTGA CGTGCAATGG CCCAGGATTC AAGAACTGTA CAAGCTGCCC TAGTGGGTAT
    CTCTTAGACT TAGGAATGTG TCAAATGGGA GCCATTTGCA AGGATGGAGA ATATGTTGAT
    GAGCATGGCC ACTGCCAGAC CTGTGAGGCC TCATGTGCCA AGTGCCAGGG ACCAACCCAG
    GAAGACTGCA CTACCTGCCC CATGACAAGG ATTTTTGATG ATGGCCGCTG TGTTTCGAAC
    TGCCCCTCAT GGAAATTTGA ATTTGAGAAC CAATGCCATC CATGCCACCA CACCTGCCAG
    AGATGCCAAG GAAGTGGCCC TACCCACTGC ACCTCCTGTG GAGCAGACAA CTATGGCCGA
    GAGCACTTCC TGTACCAGGG AGAGTGTGGA GATAGCTGCC CAGAGGGCCA CTATGCCACT
    GAGGGGAACA CCTGCCTGCC CTGCCCAGAC AACTGTGAGC TTTGCCACAG CGTGCATGTC
    TGCACAAGAT GCATGAAGGG CTACTTCATA GCGCCCACCA ACCACACATG CCAGAAGTTA
    GAGTGTGGAC AAGGTGAAGT CCAAGACCCA GACTATGAAG AATGTGTCCC TTGTGAAGAA
    GGATGTCTGG GATGCAGCTT GGATGATCCA GGAACATGTA CATCTTGCGC TATGGGGTAT
    TACAGGTTTG ATCACCATTG TTATAAAACC TGTCCTGAGA AGACCTACAG TGAGGAAGTG
    GAATGCAAGG CGTGTGATAG TAACTGTGGC AGCTGTGACC AGAATGGGTG TTACTGGTGT
    GAAGAGGGCT TCTTTCTCTT AGGTGGCAGT TGTGTGAGGA AATGTGGTCC TGGATTCTAT
    GGTGACCAAG AAATGGGAGA ATGTGAGTCC TGCCACCGAG CATGCGAAAC CTGCACAGGC
    CCTGGTCATG ACGAGTGCAG CAGCTGCCAG GAAGGACTGC AGCTGCTGCG TGGGATGTGC
    GTGCATGCCA CCAAGACCCA GGAGGAGGGC AAATTCTGGA ATGCTGTGTC CACTGCAAAC
    CTATCTGTGG TGAAGAGCCT GCTGCAGGAG CGACGAAGGT GGAAAGTTCA AATCAAAAGA
    GATATTTTGA GAAAACTCCA GCCTTGTCAT TCTTCTTGTA AAACCTGCAA TGGATCTGCA
    ACTCTGTGCA CTTCATGTCC CAAAGGTGCA TATCTTCTGG CTCAGGCCTG TGTTTCCTCC
    TGTCCCCAAG GCACATGGCC TTCCGTAAGG AGTGGGAGCT GCGAGAACTG TACGGAGGCC
    TGTGCCATCT GCTCTGGAGC CGATCTTTGC AAAAAATGCC AGATGCAGCC GGGCCACCCT
    CTCTTCCTCC ATGAAGGCAG GTGCTACTCC AAGTGCCCGG AGGGCTCTTA TGCAGAAGAC
    GGCATATGTG AACGCTGTAG CTCTCCTTGC AGAACATGTG AAGGAAACGC CACCAACTGC
    CATTCTTGTG AAGGAGGCCA CGTCCTGCAC CACGGAGTGT GCCAGGAAAA CTGCCCCGAG
    AGGCACGTGG CTGTGAAGGG GGTATGCAAG CATTGCCCAG AGATGTGTCA GGACTGCATC
    CATGAGAAAA CATGCAAAGA GTGCACGCCT GAGTTCTTCC TGCACGATGA TATGTGCCAC
    CAGTCCTGTC CCCGTGGCTT CTATGCAGAC TCGCGCCACT GTGTCCCCTG CCATAAAGAC
    TGTCTGGAGT GCAGTGGCCC CAAAGCCGAC GACTGCGAGC TCTGTCTTGA GAGTTCCTGG
    GTCCTCTATG ATGGACTGTG CTTGGAGGAG TGTCCAGCAG GAACCTATTA TGAAAAGGAG
    ACTAAGGAGT GCAGAGATTG CCACAAGTCC TGCTTGACCT GCTCATCATC TGGGACCTGC
    ACCACCTGTC AGAAAGGCCT GATCATGAAC CCTCGTGGGA GCTGCATGGC CAACGAGAAG
    TGCTCACCCT CCGAGTACTG GGATGAGGAT GCTCCCGGGT GCAAGCCCTG CCATGTTAAG
    TGCTTCCACT GCATGGGGCC GGCGGAGGAC CAGTGTCAAA CATGCCCCAT GAACAGCCTT
    CTTCTCAACA CAACCTGTGT GAAGGACTGC CCAGAGGGCT ATTATGCCGA TGAGGACAGC
    AACCGGTGTG CCCACTGCCA CAGCTCTTGC AGGACATGTG AAGGGAGACA CAGCAGGCAG
    TGCCACTCCT GCCGACCGGG CTGGTTCCAG CTAGGAAAAG AGTGCCTGCT CCAGTGCAGG
    GAAGGATATT ACGCAGACAA CTCCACTGGC CGGTGTGAGA GGTGCAACAG GAGCTGCAAG
    GGGTGCCAGG GCCCACGGCC CACAGACTGC CTGTCTTGCG ATAGATTTTT CTTTCTGCTC
    CGCTCCAAAG GAGAGTGTCA TCGCTCCTGC CCAGACCATT ACTATGTAGA GCAAAGCACA
    CAGACCTGTG AGAGATGCCA TCCGACTTGT GATCAATGCA AAGGAAAAGG AGCGTTGAAT
    TGTTTATCCT GTGTGTGGAG TTACCACCTC ATGGGAGGGA TCTGCACCTC GGACTGTCTT
    GTGGGGGAAT ACAGAGTGGG AGAGGGAGAG AAGTTTAACT GTGAAAAATG CCACGAGAGC
    TGCATGGAAT GCAAGGGACC AGGGGCCAAG AACTGCACCT TGTGCCCTGC CAACCTGGTG
    CTGCACATGG ACGACAGCCA CTGCCTCCAC TGCTGCAACA CCTCTGATCC CCCCAGTGCC
    CAGGAGTGCT GTGACTGCCA GGACACCACG GACGAATGCA TCCTTCGAAC AAGCAAGGTT
    AGGCCTGCAA CTGAGCATTT CAAGACAGCT CTGTTCATCA CCTCCTCCAT GATGCTGGTG
    CTTCTGCTCG GGGCAGCTGT GGTAGTGTGG AAGAAATCTC GTGGCCGAGT CCAGCCAGCA
    GCAAAGGCCG GCTATGAAAA ACTGGCCGAC CCCAACAAGT CTTACTCCTC CTATAAGAGC
    AGCTATAGAG AGAGCACCAG CTTTGAAGAG GATCAGGTGA TTGAGTACAG GGATCGGGAC
    TATGATGAGG ATGATGATGA TGACATCGTC TACATGGGCC AGGATGGCAC AGTCTACCGG
    AAATTTAAAT ATGGGCTGCT GGATGACGAT GACATAGATG AGCTGGAATA TGATGACGAG
    AGTTACTCCT ACTACCAGTA A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_011517071.1
    CDS537..6197
    Translation

    Target ORF information:

    RefSeq Version XM_011518769.3
    Organism Homo sapiens(human)
    Definition Homo sapiens proprotein convertase subtilisin/kexin type 5 (PCSK5), transcript variant X2, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_011518769.3

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    4201
    4261
    4321
    4381
    4441
    4501
    4561
    4621
    4681
    4741
    4801
    4861
    4921
    4981
    5041
    5101
    5161
    5221
    5281
    5341
    5401
    5461
    5521
    5581
    5641
    ATGGGCTGGG GGAGCCGCTG CTGCTGCCCG GGACGTTTGG ACCTGCTGTG CGTGCTGGCG 
    CTGCTCGGGG GCTGCCTGCT CCCCGTGTGT CGGACGCGCG TCTACACCAA CCACTGGGCA
    GTCAAAATCG CCGGGGGCTT CCCGGAGGCC AACCGTATCG CCAGCAAGTA CGGATTCATC
    AACATAGGAC AGATAGGGGC CCTGAAGGAC TACTACCACT TCTACCATAG CAGGACGATT
    AAAAGGTCAG TTATCTCGAG CAGAGGGACC CACAGTTTCA TTTCAATGGA ACCAAAGGTG
    GAATGGATCC AACAGCAAGT GGTAAAAAAG CGGACAAAGA GGGATTATGA CTTCAGTCGT
    GCCCAGTCTA CCTATTTCAA TGATCCCAAG TGGCCCAGCA TGTGGTATAT GCACTGCAGT
    GACAATACAC ATCCCTGCCA GTCTGACATG AATATCGAAG GAGCCTGGAA GAGAGGCTAC
    ACGGGAAAGA ACATTGTGGT CACTATCCTG GATGACGGAA TTGAGAGAAC CCATCCAGAT
    CTGATGCAAA ACTACGATGC TCTGGCAAGT TGCGACGTGA ATGGGAATGA CTTGGACCCA
    ATGCCTCGTT ATGATGCAAG CAACGAGAAC AAGCATGGGA CTCGCTGTGC TGGAGAAGTG
    GCAGCCGCTG CAAACAATTC GCACTGCACA GTCGGAATTG CTTTCAACGC CAAGATCGGA
    GGAGTGCGAA TGCTGGACGG AGATGTCACG GACATGGTTG AAGCAAAATC AGTTAGCTTC
    AACCCCCAGC ACGTGCACAT TTACAGCGCC AGCTGGGGCC CGGATGATGA TGGCAAGACT
    GTGGACGGAC CAGCCCCCCT CACCCGGCAA GCCTTTGAAA ACGGCGTTAG AATGGGGCGG
    AGAGGCCTCG GCTCTGTGTT TGTTTGGGCA TCTGGAAATG GTGGAAGGAG CAAAGACCAC
    TGCTCCTGTG ATGGCTACAC CAACAGCATC TACACCATCT CCATCAGCAG CACTGCAGAA
    AGCGGAAAGA AACCTTGGTA CCTGGAAGAG TGTTCATCCA CGCTGGCCAC AACCTACAGC
    AGCGGGGAGT CCTACGATAA GAAAATCATC ACTACAGATC TGAGGCAGCG TTGCACGGAC
    AACCACACTG GGACGTCAGC CTCAGCCCCC ATGGCTGCAG GCATCATTGC GCTGGCCCTG
    GAAGCCAATC CGTTTCTGAC CTGGAGAGAC GTACAGCATG TTATTGTCAG GACTTCCCGT
    GCGGGACATT TGAACGCTAA TGACTGGAAA ACCAATGCTG CTGGTTTTAA GGTGAGCCAT
    CTTTATGGAT TTGGACTGAT GGACGCAGAA GCCATGGTGA TGGAGGCAGA GAAGTGGACC
    ACCGTTCCCC GGCAGCACGT GTGTGTGGAG AGCACAGACC GACAAATCAA GACAATCCGC
    CCTAACAGTG CAGTGCGCTC CATCTACAAA GCTTCAGGCT GCTCGGATAA CCCCAACCGC
    CATGTCAACT ACCTGGAGCA CGTCGTTGTG CGCATCACCA TCACCCACCC CAGGAGAGGA
    GACCTGGCCA TCTACCTGAC CTCGCCCTCT GGAACTAGGT CTCAGCTTTT GGCCAACAGG
    CTATTTGATC ACTCCATGGA AGGATTCAAA AACTGGGAGT TCATGACCAT TCATTGCTGG
    GGAGAAAGAG CTGCTGGTGA CTGGGTCCTT GAAGTTTATG ATACTCCCTC TCAGCTAAGG
    AACTTTAAGA CTCCAGGTAA ATTGAAAGAA TGGTCTTTGG TCCTCTACGG CACCTCCGTG
    CAGCCATATT CACCAACCAA TGAATTTCCG AAAGTGGAAC GGTTCCGCTA TAGCCGAGTT
    GAAGACCCCA CAGACGACTA TGGCACAGAG GATTATGCAG GTCCCTGCGA CCCTGAGTGC
    AGTGAGGTTG GCTGTGACGG GCCAGGACCA GACCACTGCA ATGACTGTTT GCACTACTAC
    TACAAGCTGA AAAACAATAC CAGGATCTGT GTCTCCAGCT GCCCCCCTGG CCACTACCAC
    GCCGACAAGA AGCGCTGCAG GAAGTGTGCC CCCAACTGTG AGTCCTGCTT TGGGAGCCAT
    GGTGACCAAT GCATGTCCTG CAAATATGGA TACTTTCTGA ATGAAGAAAC CAACAGCTGT
    GTTACTCACT GCCCTGATGG GTCATATCAG GATACCAAGA AAAATCTTTG CCGGAAATGC
    AGTGAAAACT GCAAGACATG TACTGAATTC CATAACTGTA CAGAATGTAG GGATGGGTTA
    AGCCTGCAGG GATCCCGGTG CTCTGTCTCC TGTGAAGATG GACGGTATTT CAACGGCCAG
    GACTGCCAGC CCTGCCACCG CTTCTGCGCC ACTTGTGCTG GGGCAGGAGC TGATGGGTGC
    ATTAACTGCA CAGAGGGCTA CTTCATGGAG GATGGGAGAT GCGTGCAGAG CTGTAGTATC
    AGCTATTACT TTGACCACTC TTCAGAGAAT GGATACAAAT CCTGCAAAAA ATGTGATATC
    AGTTGTTTGA CGTGCAATGG CCCAGGATTC AAGAACTGTA CAAGCTGCCC TAGTGGGTAT
    CTCTTAGACT TAGGAATGTG TCAAATGGGA GCCATTTGCA AGGATGGAGA ATATGTTGAT
    GAGCATGGCC ACTGCCAGAC CTGTGAGGCC TCATGTGCCA AGTGCCAGGG ACCAACCCAG
    GAAGACTGCA CTACCTGCCC CATGACAAGG ATTTTTGATG ATGGCCGCTG TGTTTCGAAC
    TGCCCCTCAT GGAAATTTGA ATTTGAGAAC CAATGCCATC CATGCCACCA CACCTGCCAG
    AGATGCCAAG GAAGTGGCCC TACCCACTGC ACCTCCTGTG GAGCAGACAA CTATGGCCGA
    GAGCACTTCC TGTACCAGGG AGAGTGTGGA GATAGCTGCC CAGAGGGCCA CTATGCCACT
    GAGGGGAACA CCTGCCTGCC CTGCCCAGAC AACTGTGAGC TTTGCCACAG CGTGCATGTC
    TGCACAAGAT GCATGAAGGG CTACTTCATA GCGCCCACCA ACCACACATG CCAGAAGTTA
    GAGTGTGGAC AAGGTGAAGT CCAAGACCCA GACTATGAAG AATGTGTCCC TTGTGAAGAA
    GGATGTCTGG GATGCAGCTT GGATGATCCA GGAACATGTA CATCTTGCGC TATGGGGTAT
    TACAGGTTTG ATCACCATTG TTATAAAACC TGTCCTGAGA AGACCTACAG TGAGGAAGTG
    GAATGCAAGG CGTGTGATAG TAACTGTGGC AGCTGTGACC AGAATGGGTG TTACTGGTGT
    GAAGAGGGCT TCTTTCTCTT AGGTGGCAGT TGTGTGAGGA AATGTGGTCC TGGATTCTAT
    GGTGACCAAG AAATGGGAGA ATGTGAGTCC TGCCACCGAG CATGCGAAAC CTGCACAGGC
    CCTGGTCATG ACGAGTGCAG CAGCTGCCAG GAAGGACTGC AGCTGCTGCG TGGGATGTGC
    GTGCATGCCA CCAAGACCCA GGAGGAGGGC AAATTCTGGA ATGCTGTGTC CACTGCAAAC
    CTATCTGTGG TGAAGAGCCT GCTGCAGGAG CGACGAAGGT GGAAAGTTCA AATCAAAAGA
    GATATTTTGA GAAAACTCCA GCCTTGTCAT TCTTCTTGTA AAACCTGCAA TGGATCTGCA
    ACTCTGTGCA CTTCATGTCC CAAAGGTGCA TATCTTCTGG CTCAGGCCTG TGTTTCCTCC
    TGTCCCCAAG GCACATGGCC TTCCGTAAGG AGTGGGAGCT GCGAGAACTG TACGGAGGCC
    TGTGCCATCT GCTCTGGAGC CGATCTTTGC AAAAAATGCC AGATGCAGCC GGGCCACCCT
    CTCTTCCTCC ATGAAGGCAG GTGCTACTCC AAGTGCCCGG AGGGCTCTTA TGCAGAAGAC
    GGCATATGTG AACGCTGTAG CTCTCCTTGC AGAACATGTG AAGGAAACGC CACCAACTGC
    CATTCTTGTG AAGGAGGCCA CGTCCTGCAC CACGGAGTGT GCCAGGAAAA CTGCCCCGAG
    AGGCACGTGG CTGTGAAGGG GGTATGCAAG CATTGCCCAG AGATGTGTCA GGACTGCATC
    CATGAGAAAA CATGCAAAGA GTGCACGCCT GAGTTCTTCC TGCACGATGA TATGTGCCAC
    CAGTCCTGTC CCCGTGGCTT CTATGCAGAC TCGCGCCACT GTGTCCCCTG CCATAAAGAC
    TGTCTGGAGT GCAGTGGCCC CAAAGCCGAC GACTGCGAGC TCTGTCTTGA GAGTTCCTGG
    GTCCTCTATG ATGGACTGTG CTTGGAGGAG TGTCCAGCAG GAACCTATTA TGAAAAGGAG
    ACTAAGGAGT GCAGAGATTG CCACAAGTCC TGCTTGACCT GCTCATCATC TGGGACCTGC
    ACCACCTGTC AGAAAGGCCT GATCATGAAC CCTCGTGGGA GCTGCATGGC CAACGAGAAG
    TGCTCACCCT CCGAGTACTG GGATGAGGAT GCTCCCGGGT GCAAGCCCTG CCATGTTAAG
    TGCTTCCACT GCATGGGGCC GGCGGAGGAC CAGTGTCAAA CATGCCCCAT GAACAGCCTT
    CTTCTCAACA CAACCTGTGT GAAGGACTGC CCAGAGGGCT ATTATGCCGA TGAGGACAGC
    AACCGGTGTG CCCACTGCCA CAGCTCTTGC AGGACATGTG AAGGGAGACA CAGCAGGCAG
    TGCCACTCCT GCCGACCGGG CTGGTTCCAG CTAGGAAAAG AGTGCCTGCT CCAGTGCAGG
    GAAGGATATT ACGCAGACAA CTCCACTGGC CGGTGTGAGA GGTGCAACAG GAGCTGCAAG
    GGGTGCCAGG GCCCACGGCC CACAGACTGC CTGTCTTGCG ATAGATTTTT CTTTCTGCTC
    CGCTCCAAAG GAGAGTGTCA TCGCTCCTGC CCAGACCATT ACTATGTAGA GCAAAGCACA
    CAGACCTGTG AGAGATGCCA TCCGACTTGT GATCAATGCA AAGGAAAAGG AGCGTTGAAT
    TGTTTATCCT GTGTGTGGAG TTACCACCTC ATGGGAGGGA TCTGCACCTC GGACTGTCTT
    GTGGGGGAAT ACAGAGTGGG AGAGGGAGAG AAGTTTAACT GTGAAAAATG CCACGAGAGC
    TGCATGGAAT GCAAGGGACC AGGGGCCAAG AACTGCACCT TGTGCCCTGC CAACCTGGTG
    CTGCACATGG ACGACAGCCA CTGCCTCCAC TGCTGCAACA CCTCTGATCC CCCCAGTGCC
    CAGGAGTGCT GTGACTGCCA GGACACCACG GACGAATGCA TCCTTCGAAC AAGCAAGGTT
    AGGCCTGCAA CTGAGCATTT CAAGACAGCT CTGTTCATCA CCTCCTCCAT GATGCTGGTG
    CTTCTGCTCG GGGCAGCTGT GGTAGTGTGG AAGAAATCTC GTGGCCGAGT CCAGCCAGCA
    GCAAAGGCCG GCTATGAAAA ACTGGCCGAC CCCAACAAGT CTTACTCCTC CTATAAGAGC
    AGCTATAGAG AGAGCACCAG CTTTGAAGAG GATCAGGTGA TTGAGTACAG GGATCGGGAC
    TATGATGAGG ATGATGATGA TGACATCGTC TACATGGGCC AGGATGGCAC AGTCTACCGG
    AAATTTAAAT ATGGGCTGCT GGATGACGAT GACATAGATG AGCTGGAATA TGATGACGAG
    AGTTACTCCT ACTACCAGTA A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu59541
    Clone ID Related Accession (Same CDS sequence) XM_011518769.3 , XM_011518769.2
    Accession Version XM_011518769.2 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 5661bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2016-06-05
    Organism Homo sapiens(human)
    Product proprotein convertase subtilisin/kexin type 5 isoform X2
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011518769.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    4201
    4261
    4321
    4381
    4441
    4501
    4561
    4621
    4681
    4741
    4801
    4861
    4921
    4981
    5041
    5101
    5161
    5221
    5281
    5341
    5401
    5461
    5521
    5581
    5641
    ATGGGCTGGG GGAGCCGCTG CTGCTGCCCG GGACGTTTGG ACCTGCTGTG CGTGCTGGCG 
    CTGCTCGGGG GCTGCCTGCT CCCCGTGTGT CGGACGCGCG TCTACACCAA CCACTGGGCA
    GTCAAAATCG CCGGGGGCTT CCCGGAGGCC AACCGTATCG CCAGCAAGTA CGGATTCATC
    AACATAGGAC AGATAGGGGC CCTGAAGGAC TACTACCACT TCTACCATAG CAGGACGATT
    AAAAGGTCAG TTATCTCGAG CAGAGGGACC CACAGTTTCA TTTCAATGGA ACCAAAGGTG
    GAATGGATCC AACAGCAAGT GGTAAAAAAG CGGACAAAGA GGGATTATGA CTTCAGTCGT
    GCCCAGTCTA CCTATTTCAA TGATCCCAAG TGGCCCAGCA TGTGGTATAT GCACTGCAGT
    GACAATACAC ATCCCTGCCA GTCTGACATG AATATCGAAG GAGCCTGGAA GAGAGGCTAC
    ACGGGAAAGA ACATTGTGGT CACTATCCTG GATGACGGAA TTGAGAGAAC CCATCCAGAT
    CTGATGCAAA ACTACGATGC TCTGGCAAGT TGCGACGTGA ATGGGAATGA CTTGGACCCA
    ATGCCTCGTT ATGATGCAAG CAACGAGAAC AAGCATGGGA CTCGCTGTGC TGGAGAAGTG
    GCAGCCGCTG CAAACAATTC GCACTGCACA GTCGGAATTG CTTTCAACGC CAAGATCGGA
    GGAGTGCGAA TGCTGGACGG AGATGTCACG GACATGGTTG AAGCAAAATC AGTTAGCTTC
    AACCCCCAGC ACGTGCACAT TTACAGCGCC AGCTGGGGCC CGGATGATGA TGGCAAGACT
    GTGGACGGAC CAGCCCCCCT CACCCGGCAA GCCTTTGAAA ACGGCGTTAG AATGGGGCGG
    AGAGGCCTCG GCTCTGTGTT TGTTTGGGCA TCTGGAAATG GTGGAAGGAG CAAAGACCAC
    TGCTCCTGTG ATGGCTACAC CAACAGCATC TACACCATCT CCATCAGCAG CACTGCAGAA
    AGCGGAAAGA AACCTTGGTA CCTGGAAGAG TGTTCATCCA CGCTGGCCAC AACCTACAGC
    AGCGGGGAGT CCTACGATAA GAAAATCATC ACTACAGATC TGAGGCAGCG TTGCACGGAC
    AACCACACTG GGACGTCAGC CTCAGCCCCC ATGGCTGCAG GCATCATTGC GCTGGCCCTG
    GAAGCCAATC CGTTTCTGAC CTGGAGAGAC GTACAGCATG TTATTGTCAG GACTTCCCGT
    GCGGGACATT TGAACGCTAA TGACTGGAAA ACCAATGCTG CTGGTTTTAA GGTGAGCCAT
    CTTTATGGAT TTGGACTGAT GGACGCAGAA GCCATGGTGA TGGAGGCAGA GAAGTGGACC
    ACCGTTCCCC GGCAGCACGT GTGTGTGGAG AGCACAGACC GACAAATCAA GACAATCCGC
    CCTAACAGTG CAGTGCGCTC CATCTACAAA GCTTCAGGCT GCTCGGATAA CCCCAACCGC
    CATGTCAACT ACCTGGAGCA CGTCGTTGTG CGCATCACCA TCACCCACCC CAGGAGAGGA
    GACCTGGCCA TCTACCTGAC CTCGCCCTCT GGAACTAGGT CTCAGCTTTT GGCCAACAGG
    CTATTTGATC ACTCCATGGA AGGATTCAAA AACTGGGAGT TCATGACCAT TCATTGCTGG
    GGAGAAAGAG CTGCTGGTGA CTGGGTCCTT GAAGTTTATG ATACTCCCTC TCAGCTAAGG
    AACTTTAAGA CTCCAGGTAA ATTGAAAGAA TGGTCTTTGG TCCTCTACGG CACCTCCGTG
    CAGCCATATT CACCAACCAA TGAATTTCCG AAAGTGGAAC GGTTCCGCTA TAGCCGAGTT
    GAAGACCCCA CAGACGACTA TGGCACAGAG GATTATGCAG GTCCCTGCGA CCCTGAGTGC
    AGTGAGGTTG GCTGTGACGG GCCAGGACCA GACCACTGCA ATGACTGTTT GCACTACTAC
    TACAAGCTGA AAAACAATAC CAGGATCTGT GTCTCCAGCT GCCCCCCTGG CCACTACCAC
    GCCGACAAGA AGCGCTGCAG GAAGTGTGCC CCCAACTGTG AGTCCTGCTT TGGGAGCCAT
    GGTGACCAAT GCATGTCCTG CAAATATGGA TACTTTCTGA ATGAAGAAAC CAACAGCTGT
    GTTACTCACT GCCCTGATGG GTCATATCAG GATACCAAGA AAAATCTTTG CCGGAAATGC
    AGTGAAAACT GCAAGACATG TACTGAATTC CATAACTGTA CAGAATGTAG GGATGGGTTA
    AGCCTGCAGG GATCCCGGTG CTCTGTCTCC TGTGAAGATG GACGGTATTT CAACGGCCAG
    GACTGCCAGC CCTGCCACCG CTTCTGCGCC ACTTGTGCTG GGGCAGGAGC TGATGGGTGC
    ATTAACTGCA CAGAGGGCTA CTTCATGGAG GATGGGAGAT GCGTGCAGAG CTGTAGTATC
    AGCTATTACT TTGACCACTC TTCAGAGAAT GGATACAAAT CCTGCAAAAA ATGTGATATC
    AGTTGTTTGA CGTGCAATGG CCCAGGATTC AAGAACTGTA CAAGCTGCCC TAGTGGGTAT
    CTCTTAGACT TAGGAATGTG TCAAATGGGA GCCATTTGCA AGGATGGAGA ATATGTTGAT
    GAGCATGGCC ACTGCCAGAC CTGTGAGGCC TCATGTGCCA AGTGCCAGGG ACCAACCCAG
    GAAGACTGCA CTACCTGCCC CATGACAAGG ATTTTTGATG ATGGCCGCTG TGTTTCGAAC
    TGCCCCTCAT GGAAATTTGA ATTTGAGAAC CAATGCCATC CATGCCACCA CACCTGCCAG
    AGATGCCAAG GAAGTGGCCC TACCCACTGC ACCTCCTGTG GAGCAGACAA CTATGGCCGA
    GAGCACTTCC TGTACCAGGG AGAGTGTGGA GATAGCTGCC CAGAGGGCCA CTATGCCACT
    GAGGGGAACA CCTGCCTGCC CTGCCCAGAC AACTGTGAGC TTTGCCACAG CGTGCATGTC
    TGCACAAGAT GCATGAAGGG CTACTTCATA GCGCCCACCA ACCACACATG CCAGAAGTTA
    GAGTGTGGAC AAGGTGAAGT CCAAGACCCA GACTATGAAG AATGTGTCCC TTGTGAAGAA
    GGATGTCTGG GATGCAGCTT GGATGATCCA GGAACATGTA CATCTTGCGC TATGGGGTAT
    TACAGGTTTG ATCACCATTG TTATAAAACC TGTCCTGAGA AGACCTACAG TGAGGAAGTG
    GAATGCAAGG CGTGTGATAG TAACTGTGGC AGCTGTGACC AGAATGGGTG TTACTGGTGT
    GAAGAGGGCT TCTTTCTCTT AGGTGGCAGT TGTGTGAGGA AATGTGGTCC TGGATTCTAT
    GGTGACCAAG AAATGGGAGA ATGTGAGTCC TGCCACCGAG CATGCGAAAC CTGCACAGGC
    CCTGGTCATG ACGAGTGCAG CAGCTGCCAG GAAGGACTGC AGCTGCTGCG TGGGATGTGC
    GTGCATGCCA CCAAGACCCA GGAGGAGGGC AAATTCTGGA ATGCTGTGTC CACTGCAAAC
    CTATCTGTGG TGAAGAGCCT GCTGCAGGAG CGACGAAGGT GGAAAGTTCA AATCAAAAGA
    GATATTTTGA GAAAACTCCA GCCTTGTCAT TCTTCTTGTA AAACCTGCAA TGGATCTGCA
    ACTCTGTGCA CTTCATGTCC CAAAGGTGCA TATCTTCTGG CTCAGGCCTG TGTTTCCTCC
    TGTCCCCAAG GCACATGGCC TTCCGTAAGG AGTGGGAGCT GCGAGAACTG TACGGAGGCC
    TGTGCCATCT GCTCTGGAGC CGATCTTTGC AAAAAATGCC AGATGCAGCC GGGCCACCCT
    CTCTTCCTCC ATGAAGGCAG GTGCTACTCC AAGTGCCCGG AGGGCTCTTA TGCAGAAGAC
    GGCATATGTG AACGCTGTAG CTCTCCTTGC AGAACATGTG AAGGAAACGC CACCAACTGC
    CATTCTTGTG AAGGAGGCCA CGTCCTGCAC CACGGAGTGT GCCAGGAAAA CTGCCCCGAG
    AGGCACGTGG CTGTGAAGGG GGTATGCAAG CATTGCCCAG AGATGTGTCA GGACTGCATC
    CATGAGAAAA CATGCAAAGA GTGCACGCCT GAGTTCTTCC TGCACGATGA TATGTGCCAC
    CAGTCCTGTC CCCGTGGCTT CTATGCAGAC TCGCGCCACT GTGTCCCCTG CCATAAAGAC
    TGTCTGGAGT GCAGTGGCCC CAAAGCCGAC GACTGCGAGC TCTGTCTTGA GAGTTCCTGG
    GTCCTCTATG ATGGACTGTG CTTGGAGGAG TGTCCAGCAG GAACCTATTA TGAAAAGGAG
    ACTAAGGAGT GCAGAGATTG CCACAAGTCC TGCTTGACCT GCTCATCATC TGGGACCTGC
    ACCACCTGTC AGAAAGGCCT GATCATGAAC CCTCGTGGGA GCTGCATGGC CAACGAGAAG
    TGCTCACCCT CCGAGTACTG GGATGAGGAT GCTCCCGGGT GCAAGCCCTG CCATGTTAAG
    TGCTTCCACT GCATGGGGCC GGCGGAGGAC CAGTGTCAAA CATGCCCCAT GAACAGCCTT
    CTTCTCAACA CAACCTGTGT GAAGGACTGC CCAGAGGGCT ATTATGCCGA TGAGGACAGC
    AACCGGTGTG CCCACTGCCA CAGCTCTTGC AGGACATGTG AAGGGAGACA CAGCAGGCAG
    TGCCACTCCT GCCGACCGGG CTGGTTCCAG CTAGGAAAAG AGTGCCTGCT CCAGTGCAGG
    GAAGGATATT ACGCAGACAA CTCCACTGGC CGGTGTGAGA GGTGCAACAG GAGCTGCAAG
    GGGTGCCAGG GCCCACGGCC CACAGACTGC CTGTCTTGCG ATAGATTTTT CTTTCTGCTC
    CGCTCCAAAG GAGAGTGTCA TCGCTCCTGC CCAGACCATT ACTATGTAGA GCAAAGCACA
    CAGACCTGTG AGAGATGCCA TCCGACTTGT GATCAATGCA AAGGAAAAGG AGCGTTGAAT
    TGTTTATCCT GTGTGTGGAG TTACCACCTC ATGGGAGGGA TCTGCACCTC GGACTGTCTT
    GTGGGGGAAT ACAGAGTGGG AGAGGGAGAG AAGTTTAACT GTGAAAAATG CCACGAGAGC
    TGCATGGAAT GCAAGGGACC AGGGGCCAAG AACTGCACCT TGTGCCCTGC CAACCTGGTG
    CTGCACATGG ACGACAGCCA CTGCCTCCAC TGCTGCAACA CCTCTGATCC CCCCAGTGCC
    CAGGAGTGCT GTGACTGCCA GGACACCACG GACGAATGCA TCCTTCGAAC AAGCAAGGTT
    AGGCCTGCAA CTGAGCATTT CAAGACAGCT CTGTTCATCA CCTCCTCCAT GATGCTGGTG
    CTTCTGCTCG GGGCAGCTGT GGTAGTGTGG AAGAAATCTC GTGGCCGAGT CCAGCCAGCA
    GCAAAGGCCG GCTATGAAAA ACTGGCCGAC CCCAACAAGT CTTACTCCTC CTATAAGAGC
    AGCTATAGAG AGAGCACCAG CTTTGAAGAG GATCAGGTGA TTGAGTACAG GGATCGGGAC
    TATGATGAGG ATGATGATGA TGACATCGTC TACATGGGCC AGGATGGCAC AGTCTACCGG
    AAATTTAAAT ATGGGCTGCT GGATGACGAT GACATAGATG AGCTGGAATA TGATGACGAG
    AGTTACTCCT ACTACCAGTA A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_011517071.1
    CDS582..6242
    Translation

    Target ORF information:

    RefSeq Version XM_011518769.2
    Organism Homo sapiens(human)
    Definition Homo sapiens proprotein convertase subtilisin/kexin type 5 (PCSK5), transcript variant X2, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_011518769.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    4201
    4261
    4321
    4381
    4441
    4501
    4561
    4621
    4681
    4741
    4801
    4861
    4921
    4981
    5041
    5101
    5161
    5221
    5281
    5341
    5401
    5461
    5521
    5581
    5641
    ATGGGCTGGG GGAGCCGCTG CTGCTGCCCG GGACGTTTGG ACCTGCTGTG CGTGCTGGCG 
    CTGCTCGGGG GCTGCCTGCT CCCCGTGTGT CGGACGCGCG TCTACACCAA CCACTGGGCA
    GTCAAAATCG CCGGGGGCTT CCCGGAGGCC AACCGTATCG CCAGCAAGTA CGGATTCATC
    AACATAGGAC AGATAGGGGC CCTGAAGGAC TACTACCACT TCTACCATAG CAGGACGATT
    AAAAGGTCAG TTATCTCGAG CAGAGGGACC CACAGTTTCA TTTCAATGGA ACCAAAGGTG
    GAATGGATCC AACAGCAAGT GGTAAAAAAG CGGACAAAGA GGGATTATGA CTTCAGTCGT
    GCCCAGTCTA CCTATTTCAA TGATCCCAAG TGGCCCAGCA TGTGGTATAT GCACTGCAGT
    GACAATACAC ATCCCTGCCA GTCTGACATG AATATCGAAG GAGCCTGGAA GAGAGGCTAC
    ACGGGAAAGA ACATTGTGGT CACTATCCTG GATGACGGAA TTGAGAGAAC CCATCCAGAT
    CTGATGCAAA ACTACGATGC TCTGGCAAGT TGCGACGTGA ATGGGAATGA CTTGGACCCA
    ATGCCTCGTT ATGATGCAAG CAACGAGAAC AAGCATGGGA CTCGCTGTGC TGGAGAAGTG
    GCAGCCGCTG CAAACAATTC GCACTGCACA GTCGGAATTG CTTTCAACGC CAAGATCGGA
    GGAGTGCGAA TGCTGGACGG AGATGTCACG GACATGGTTG AAGCAAAATC AGTTAGCTTC
    AACCCCCAGC ACGTGCACAT TTACAGCGCC AGCTGGGGCC CGGATGATGA TGGCAAGACT
    GTGGACGGAC CAGCCCCCCT CACCCGGCAA GCCTTTGAAA ACGGCGTTAG AATGGGGCGG
    AGAGGCCTCG GCTCTGTGTT TGTTTGGGCA TCTGGAAATG GTGGAAGGAG CAAAGACCAC
    TGCTCCTGTG ATGGCTACAC CAACAGCATC TACACCATCT CCATCAGCAG CACTGCAGAA
    AGCGGAAAGA AACCTTGGTA CCTGGAAGAG TGTTCATCCA CGCTGGCCAC AACCTACAGC
    AGCGGGGAGT CCTACGATAA GAAAATCATC ACTACAGATC TGAGGCAGCG TTGCACGGAC
    AACCACACTG GGACGTCAGC CTCAGCCCCC ATGGCTGCAG GCATCATTGC GCTGGCCCTG
    GAAGCCAATC CGTTTCTGAC CTGGAGAGAC GTACAGCATG TTATTGTCAG GACTTCCCGT
    GCGGGACATT TGAACGCTAA TGACTGGAAA ACCAATGCTG CTGGTTTTAA GGTGAGCCAT
    CTTTATGGAT TTGGACTGAT GGACGCAGAA GCCATGGTGA TGGAGGCAGA GAAGTGGACC
    ACCGTTCCCC GGCAGCACGT GTGTGTGGAG AGCACAGACC GACAAATCAA GACAATCCGC
    CCTAACAGTG CAGTGCGCTC CATCTACAAA GCTTCAGGCT GCTCGGATAA CCCCAACCGC
    CATGTCAACT ACCTGGAGCA CGTCGTTGTG CGCATCACCA TCACCCACCC CAGGAGAGGA
    GACCTGGCCA TCTACCTGAC CTCGCCCTCT GGAACTAGGT CTCAGCTTTT GGCCAACAGG
    CTATTTGATC ACTCCATGGA AGGATTCAAA AACTGGGAGT TCATGACCAT TCATTGCTGG
    GGAGAAAGAG CTGCTGGTGA CTGGGTCCTT GAAGTTTATG ATACTCCCTC TCAGCTAAGG
    AACTTTAAGA CTCCAGGTAA ATTGAAAGAA TGGTCTTTGG TCCTCTACGG CACCTCCGTG
    CAGCCATATT CACCAACCAA TGAATTTCCG AAAGTGGAAC GGTTCCGCTA TAGCCGAGTT
    GAAGACCCCA CAGACGACTA TGGCACAGAG GATTATGCAG GTCCCTGCGA CCCTGAGTGC
    AGTGAGGTTG GCTGTGACGG GCCAGGACCA GACCACTGCA ATGACTGTTT GCACTACTAC
    TACAAGCTGA AAAACAATAC CAGGATCTGT GTCTCCAGCT GCCCCCCTGG CCACTACCAC
    GCCGACAAGA AGCGCTGCAG GAAGTGTGCC CCCAACTGTG AGTCCTGCTT TGGGAGCCAT
    GGTGACCAAT GCATGTCCTG CAAATATGGA TACTTTCTGA ATGAAGAAAC CAACAGCTGT
    GTTACTCACT GCCCTGATGG GTCATATCAG GATACCAAGA AAAATCTTTG CCGGAAATGC
    AGTGAAAACT GCAAGACATG TACTGAATTC CATAACTGTA CAGAATGTAG GGATGGGTTA
    AGCCTGCAGG GATCCCGGTG CTCTGTCTCC TGTGAAGATG GACGGTATTT CAACGGCCAG
    GACTGCCAGC CCTGCCACCG CTTCTGCGCC ACTTGTGCTG GGGCAGGAGC TGATGGGTGC
    ATTAACTGCA CAGAGGGCTA CTTCATGGAG GATGGGAGAT GCGTGCAGAG CTGTAGTATC
    AGCTATTACT TTGACCACTC TTCAGAGAAT GGATACAAAT CCTGCAAAAA ATGTGATATC
    AGTTGTTTGA CGTGCAATGG CCCAGGATTC AAGAACTGTA CAAGCTGCCC TAGTGGGTAT
    CTCTTAGACT TAGGAATGTG TCAAATGGGA GCCATTTGCA AGGATGGAGA ATATGTTGAT
    GAGCATGGCC ACTGCCAGAC CTGTGAGGCC TCATGTGCCA AGTGCCAGGG ACCAACCCAG
    GAAGACTGCA CTACCTGCCC CATGACAAGG ATTTTTGATG ATGGCCGCTG TGTTTCGAAC
    TGCCCCTCAT GGAAATTTGA ATTTGAGAAC CAATGCCATC CATGCCACCA CACCTGCCAG
    AGATGCCAAG GAAGTGGCCC TACCCACTGC ACCTCCTGTG GAGCAGACAA CTATGGCCGA
    GAGCACTTCC TGTACCAGGG AGAGTGTGGA GATAGCTGCC CAGAGGGCCA CTATGCCACT
    GAGGGGAACA CCTGCCTGCC CTGCCCAGAC AACTGTGAGC TTTGCCACAG CGTGCATGTC
    TGCACAAGAT GCATGAAGGG CTACTTCATA GCGCCCACCA ACCACACATG CCAGAAGTTA
    GAGTGTGGAC AAGGTGAAGT CCAAGACCCA GACTATGAAG AATGTGTCCC TTGTGAAGAA
    GGATGTCTGG GATGCAGCTT GGATGATCCA GGAACATGTA CATCTTGCGC TATGGGGTAT
    TACAGGTTTG ATCACCATTG TTATAAAACC TGTCCTGAGA AGACCTACAG TGAGGAAGTG
    GAATGCAAGG CGTGTGATAG TAACTGTGGC AGCTGTGACC AGAATGGGTG TTACTGGTGT
    GAAGAGGGCT TCTTTCTCTT AGGTGGCAGT TGTGTGAGGA AATGTGGTCC TGGATTCTAT
    GGTGACCAAG AAATGGGAGA ATGTGAGTCC TGCCACCGAG CATGCGAAAC CTGCACAGGC
    CCTGGTCATG ACGAGTGCAG CAGCTGCCAG GAAGGACTGC AGCTGCTGCG TGGGATGTGC
    GTGCATGCCA CCAAGACCCA GGAGGAGGGC AAATTCTGGA ATGCTGTGTC CACTGCAAAC
    CTATCTGTGG TGAAGAGCCT GCTGCAGGAG CGACGAAGGT GGAAAGTTCA AATCAAAAGA
    GATATTTTGA GAAAACTCCA GCCTTGTCAT TCTTCTTGTA AAACCTGCAA TGGATCTGCA
    ACTCTGTGCA CTTCATGTCC CAAAGGTGCA TATCTTCTGG CTCAGGCCTG TGTTTCCTCC
    TGTCCCCAAG GCACATGGCC TTCCGTAAGG AGTGGGAGCT GCGAGAACTG TACGGAGGCC
    TGTGCCATCT GCTCTGGAGC CGATCTTTGC AAAAAATGCC AGATGCAGCC GGGCCACCCT
    CTCTTCCTCC ATGAAGGCAG GTGCTACTCC AAGTGCCCGG AGGGCTCTTA TGCAGAAGAC
    GGCATATGTG AACGCTGTAG CTCTCCTTGC AGAACATGTG AAGGAAACGC CACCAACTGC
    CATTCTTGTG AAGGAGGCCA CGTCCTGCAC CACGGAGTGT GCCAGGAAAA CTGCCCCGAG
    AGGCACGTGG CTGTGAAGGG GGTATGCAAG CATTGCCCAG AGATGTGTCA GGACTGCATC
    CATGAGAAAA CATGCAAAGA GTGCACGCCT GAGTTCTTCC TGCACGATGA TATGTGCCAC
    CAGTCCTGTC CCCGTGGCTT CTATGCAGAC TCGCGCCACT GTGTCCCCTG CCATAAAGAC
    TGTCTGGAGT GCAGTGGCCC CAAAGCCGAC GACTGCGAGC TCTGTCTTGA GAGTTCCTGG
    GTCCTCTATG ATGGACTGTG CTTGGAGGAG TGTCCAGCAG GAACCTATTA TGAAAAGGAG
    ACTAAGGAGT GCAGAGATTG CCACAAGTCC TGCTTGACCT GCTCATCATC TGGGACCTGC
    ACCACCTGTC AGAAAGGCCT GATCATGAAC CCTCGTGGGA GCTGCATGGC CAACGAGAAG
    TGCTCACCCT CCGAGTACTG GGATGAGGAT GCTCCCGGGT GCAAGCCCTG CCATGTTAAG
    TGCTTCCACT GCATGGGGCC GGCGGAGGAC CAGTGTCAAA CATGCCCCAT GAACAGCCTT
    CTTCTCAACA CAACCTGTGT GAAGGACTGC CCAGAGGGCT ATTATGCCGA TGAGGACAGC
    AACCGGTGTG CCCACTGCCA CAGCTCTTGC AGGACATGTG AAGGGAGACA CAGCAGGCAG
    TGCCACTCCT GCCGACCGGG CTGGTTCCAG CTAGGAAAAG AGTGCCTGCT CCAGTGCAGG
    GAAGGATATT ACGCAGACAA CTCCACTGGC CGGTGTGAGA GGTGCAACAG GAGCTGCAAG
    GGGTGCCAGG GCCCACGGCC CACAGACTGC CTGTCTTGCG ATAGATTTTT CTTTCTGCTC
    CGCTCCAAAG GAGAGTGTCA TCGCTCCTGC CCAGACCATT ACTATGTAGA GCAAAGCACA
    CAGACCTGTG AGAGATGCCA TCCGACTTGT GATCAATGCA AAGGAAAAGG AGCGTTGAAT
    TGTTTATCCT GTGTGTGGAG TTACCACCTC ATGGGAGGGA TCTGCACCTC GGACTGTCTT
    GTGGGGGAAT ACAGAGTGGG AGAGGGAGAG AAGTTTAACT GTGAAAAATG CCACGAGAGC
    TGCATGGAAT GCAAGGGACC AGGGGCCAAG AACTGCACCT TGTGCCCTGC CAACCTGGTG
    CTGCACATGG ACGACAGCCA CTGCCTCCAC TGCTGCAACA CCTCTGATCC CCCCAGTGCC
    CAGGAGTGCT GTGACTGCCA GGACACCACG GACGAATGCA TCCTTCGAAC AAGCAAGGTT
    AGGCCTGCAA CTGAGCATTT CAAGACAGCT CTGTTCATCA CCTCCTCCAT GATGCTGGTG
    CTTCTGCTCG GGGCAGCTGT GGTAGTGTGG AAGAAATCTC GTGGCCGAGT CCAGCCAGCA
    GCAAAGGCCG GCTATGAAAA ACTGGCCGAC CCCAACAAGT CTTACTCCTC CTATAAGAGC
    AGCTATAGAG AGAGCACCAG CTTTGAAGAG GATCAGGTGA TTGAGTACAG GGATCGGGAC
    TATGATGAGG ATGATGATGA TGACATCGTC TACATGGGCC AGGATGGCAC AGTCTACCGG
    AAATTTAAAT ATGGGCTGCT GGATGACGAT GACATAGATG AGCTGGAATA TGATGACGAG
    AGTTACTCCT ACTACCAGTA A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu59542
    Clone ID Related Accession (Same CDS sequence) XM_011518770.2
    Accession Version XM_011518770.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 4326bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-05
    Organism Homo sapiens(human)
    Product proprotein convertase subtilisin/kexin type 5 isoform X3
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011518770.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    4201
    4261
    4321
    ATGGACGCAG AAGCCATGGT GATGGAGGCA GAGAAGTGGA CCACCGTTCC CCGGCAGCAC 
    GTGTGTGTGG AGAGCACAGA CCGACAAATC AAGACAATCC GCCCTAACAG TGCAGTGCGC
    TCCATCTACA AAGCTTCAGG CTGCTCGGAT AACCCCAACC GCCATGTCAA CTACCTGGAG
    CACGTCGTTG TGCGCATCAC CATCACCCAC CCCAGGAGAG GAGACCTGGC CATCTACCTG
    ACCTCGCCCT CTGGAACTAG GTCTCAGCTT TTGGCCAACA GGCTATTTGA TCACTCCATG
    GAAGGATTCA AAAACTGGGA GTTCATGACC ATTCATTGCT GGGGAGAAAG AGCTGCTGGT
    GACTGGGTCC TTGAAGTTTA TGATACTCCC TCTCAGCTAA GGAACTTTAA GACTCCAGGT
    AAATTGAAAG AATGGTCTTT GGTCCTCTAC GGCACCTCCG TGCAGCCATA TTCACCAACC
    AATGAATTTC CGAAAGTGGA ACGGTTCCGC TATAGCCGAG TTGAAGACCC CACAGACGAC
    TATGGCACAG AGGATTATGC AGGTCCCTGC GACCCTGAGT GCAGTGAGGT TGGCTGTGAC
    GGGCCAGGAC CAGACCACTG CAATGACTGT TTGCACTACT ACTACAAGCT GAAAAACAAT
    ACCAGGATCT GTGTCTCCAG CTGCCCCCCT GGCCACTACC ACGCCGACAA GAAGCGCTGC
    AGGAAGTGTG CCCCCAACTG TGAGTCCTGC TTTGGGAGCC ATGGTGACCA ATGCATGTCC
    TGCAAATATG GATACTTTCT GAATGAAGAA ACCAACAGCT GTGTTACTCA CTGCCCTGAT
    GGGTCATATC AGGATACCAA GAAAAATCTT TGCCGGAAAT GCAGTGAAAA CTGCAAGACA
    TGTACTGAAT TCCATAACTG TACAGAATGT AGGGATGGGT TAAGCCTGCA GGGATCCCGG
    TGCTCTGTCT CCTGTGAAGA TGGACGGTAT TTCAACGGCC AGGACTGCCA GCCCTGCCAC
    CGCTTCTGCG CCACTTGTGC TGGGGCAGGA GCTGATGGGT GCATTAACTG CACAGAGGGC
    TACTTCATGG AGGATGGGAG ATGCGTGCAG AGCTGTAGTA TCAGCTATTA CTTTGACCAC
    TCTTCAGAGA ATGGATACAA ATCCTGCAAA AAATGTGATA TCAGTTGTTT GACGTGCAAT
    GGCCCAGGAT TCAAGAACTG TACAAGCTGC CCTAGTGGGT ATCTCTTAGA CTTAGGAATG
    TGTCAAATGG GAGCCATTTG CAAGGATGGA GAATATGTTG ATGAGCATGG CCACTGCCAG
    ACCTGTGAGG CCTCATGTGC CAAGTGCCAG GGACCAACCC AGGAAGACTG CACTACCTGC
    CCCATGACAA GGATTTTTGA TGATGGCCGC TGTGTTTCGA ACTGCCCCTC ATGGAAATTT
    GAATTTGAGA ACCAATGCCA TCCATGCCAC CACACCTGCC AGAGATGCCA AGGAAGTGGC
    CCTACCCACT GCACCTCCTG TGGAGCAGAC AACTATGGCC GAGAGCACTT CCTGTACCAG
    GGAGAGTGTG GAGATAGCTG CCCAGAGGGC CACTATGCCA CTGAGGGGAA CACCTGCCTG
    CCCTGCCCAG ACAACTGTGA GCTTTGCCAC AGCGTGCATG TCTGCACAAG ATGCATGAAG
    GGCTACTTCA TAGCGCCCAC CAACCACACA TGCCAGAAGT TAGAGTGTGG ACAAGGTGAA
    GTCCAAGACC CAGACTATGA AGAATGTGTC CCTTGTGAAG AAGGATGTCT GGGATGCAGC
    TTGGATGATC CAGGAACATG TACATCTTGC GCTATGGGGT ATTACAGGTT TGATCACCAT
    TGTTATAAAA CCTGTCCTGA GAAGACCTAC AGTGAGGAAG TGGAATGCAA GGCGTGTGAT
    AGTAACTGTG GCAGCTGTGA CCAGAATGGG TGTTACTGGT GTGAAGAGGG CTTCTTTCTC
    TTAGGTGGCA GTTGTGTGAG GAAATGTGGT CCTGGATTCT ATGGTGACCA AGAAATGGGA
    GAATGTGAGT CCTGCCACCG AGCATGCGAA ACCTGCACAG GCCCTGGTCA TGACGAGTGC
    AGCAGCTGCC AGGAAGGACT GCAGCTGCTG CGTGGGATGT GCGTGCATGC CACCAAGACC
    CAGGAGGAGG GCAAATTCTG GAATGAAGCT GTGTCCACTG CAAACCTATC TGTGGTGAAG
    AGCCTGCTGC AGGAGCGACG AAGGTGGAAA GTTCAAATCA AAAGAGATAT TTTGAGAAAA
    CTCCAGCCTT GTCATTCTTC TTGTAAAACC TGCAATGGAT CTGCAACTCT GTGCACTTCA
    TGTCCCAAAG GTGCATATCT TCTGGCTCAG GCCTGTGTTT CCTCCTGTCC CCAAGGCACA
    TGGCCTTCCG TAAGGAGTGG GAGCTGCGAG AACTGTACGG AGGCCTGTGC CATCTGCTCT
    GGAGCCGATC TTTGCAAAAA ATGCCAGATG CAGCCGGGCC ACCCTCTCTT CCTCCATGAA
    GGCAGGTGCT ACTCCAAGTG CCCGGAGGGC TCTTATGCAG AAGACGGCAT ATGTGAACGC
    TGTAGCTCTC CTTGCAGAAC ATGTGAAGGA AACGCCACCA ACTGCCATTC TTGTGAAGGA
    GGCCACGTCC TGCACCACGG AGTGTGCCAG GAAAACTGCC CCGAGAGGCA CGTGGCTGTG
    AAGGGGGTAT GCAAGCATTG CCCAGAGATG TGTCAGGACT GCATCCATGA GAAAACATGC
    AAAGAGTGCA CGCCTGAGTT CTTCCTGCAC GATGATATGT GCCACCAGTC CTGTCCCCGT
    GGCTTCTATG CAGACTCGCG CCACTGTGTC CCCTGCCATA AAGACTGTCT GGAGTGCAGT
    GGCCCCAAAG CCGACGACTG CGAGCTCTGT CTTGAGAGTT CCTGGGTCCT CTATGATGGA
    CTGTGCTTGG AGGAGTGTCC AGCAGGAACC TATTATGAAA AGGAGACTAA GGAGTGCAGA
    GATTGCCACA AGTCCTGCTT GACCTGCTCA TCATCTGGGA CCTGCACCAC CTGTCAGAAA
    GGCCTGATCA TGAACCCTCG TGGGAGCTGC ATGGCCAACG AGAAGTGCTC ACCCTCCGAG
    TACTGGGATG AGGATGCTCC CGGGTGCAAG CCCTGCCATG TTAAGTGCTT CCACTGCATG
    GGGCCGGCGG AGGACCAGTG TCAAACATGC CCCATGAACA GCCTTCTTCT CAACACAACC
    TGTGTGAAGG ACTGCCCAGA GGGCTATTAT GCCGATGAGG ACAGCAACCG GTGTGCCCAC
    TGCCACAGCT CTTGCAGGAC ATGTGAAGGG AGACACAGCA GGCAGTGCCA CTCCTGCCGA
    CCGGGCTGGT TCCAGCTAGG AAAAGAGTGC CTGCTCCAGT GCAGGGAAGG ATATTACGCA
    GACAACTCCA CTGGCCGGTG TGAGAGGTGC AACAGGAGCT GCAAGGGGTG CCAGGGCCCA
    CGGCCCACAG ACTGCCTGTC TTGCGATAGA TTTTTCTTTC TGCTCCGCTC CAAAGGAGAG
    TGTCATCGCT CCTGCCCAGA CCATTACTAT GTAGAGCAAA GCACACAGAC CTGTGAGAGA
    TGCCATCCGA CTTGTGATCA ATGCAAAGGA AAAGGAGCGT TGAATTGTTT ATCCTGTGTG
    TGGAGTTACC ACCTCATGGG AGGGATCTGC ACCTCGGACT GTCTTGTGGG GGAATACAGA
    GTGGGAGAGG GAGAGAAGTT TAACTGTGAA AAATGCCACG AGAGCTGCAT GGAATGCAAG
    GGACCAGGGG CCAAGAACTG CACCTTGTGC CCTGCCAACC TGGTGCTGCA CATGGACGAC
    AGCCACTGCC TCCACTGCTG CAACACCTCT GATCCCCCCA GTGCCCAGGA GTGCTGTGAC
    TGCCAGGACA CCACGGACGA ATGCATCCTT CGAACAAGCA AGGTTAGGCC TGCAACTGAG
    CATTTCAAGA CAGCTCTGTT CATCACCTCC TCCATGATGC TGGTGCTTCT GCTCGGGGCA
    GCTGTGGTAG TGTGGAAGAA ATCTCGTGGC CGAGTCCAGC CAGCAGCAAA GGCCGGCTAT
    GAAAAACTGG CCGACCCCAA CAAGTCTTAC TCCTCCTATA AGAGCAGCTA TAGAGAGAGC
    ACCAGCTTTG AAGAGGATCA GGTGATTGAG TACAGGGATC GGGACTATGA TGAGGATGAT
    GATGATGACA TCGTCTACAT GGGCCAGGAT GGCACAGTCT ACCGGAAATT TAAATATGGG
    CTGCTGGATG ACGATGACAT AGATGAGCTG GAATATGATG ACGAGAGTTA CTCCTACTAC
    CAGTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_011517072.1
    CDS4693..9018
    Translation

    Target ORF information:

    RefSeq Version XM_011518770.2
    Organism Homo sapiens(human)
    Definition Homo sapiens proprotein convertase subtilisin/kexin type 5 (PCSK5), transcript variant X3, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_011518770.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    4201
    4261
    4321
    ATGGACGCAG AAGCCATGGT GATGGAGGCA GAGAAGTGGA CCACCGTTCC CCGGCAGCAC 
    GTGTGTGTGG AGAGCACAGA CCGACAAATC AAGACAATCC GCCCTAACAG TGCAGTGCGC
    TCCATCTACA AAGCTTCAGG CTGCTCGGAT AACCCCAACC GCCATGTCAA CTACCTGGAG
    CACGTCGTTG TGCGCATCAC CATCACCCAC CCCAGGAGAG GAGACCTGGC CATCTACCTG
    ACCTCGCCCT CTGGAACTAG GTCTCAGCTT TTGGCCAACA GGCTATTTGA TCACTCCATG
    GAAGGATTCA AAAACTGGGA GTTCATGACC ATTCATTGCT GGGGAGAAAG AGCTGCTGGT
    GACTGGGTCC TTGAAGTTTA TGATACTCCC TCTCAGCTAA GGAACTTTAA GACTCCAGGT
    AAATTGAAAG AATGGTCTTT GGTCCTCTAC GGCACCTCCG TGCAGCCATA TTCACCAACC
    AATGAATTTC CGAAAGTGGA ACGGTTCCGC TATAGCCGAG TTGAAGACCC CACAGACGAC
    TATGGCACAG AGGATTATGC AGGTCCCTGC GACCCTGAGT GCAGTGAGGT TGGCTGTGAC
    GGGCCAGGAC CAGACCACTG CAATGACTGT TTGCACTACT ACTACAAGCT GAAAAACAAT
    ACCAGGATCT GTGTCTCCAG CTGCCCCCCT GGCCACTACC ACGCCGACAA GAAGCGCTGC
    AGGAAGTGTG CCCCCAACTG TGAGTCCTGC TTTGGGAGCC ATGGTGACCA ATGCATGTCC
    TGCAAATATG GATACTTTCT GAATGAAGAA ACCAACAGCT GTGTTACTCA CTGCCCTGAT
    GGGTCATATC AGGATACCAA GAAAAATCTT TGCCGGAAAT GCAGTGAAAA CTGCAAGACA
    TGTACTGAAT TCCATAACTG TACAGAATGT AGGGATGGGT TAAGCCTGCA GGGATCCCGG
    TGCTCTGTCT CCTGTGAAGA TGGACGGTAT TTCAACGGCC AGGACTGCCA GCCCTGCCAC
    CGCTTCTGCG CCACTTGTGC TGGGGCAGGA GCTGATGGGT GCATTAACTG CACAGAGGGC
    TACTTCATGG AGGATGGGAG ATGCGTGCAG AGCTGTAGTA TCAGCTATTA CTTTGACCAC
    TCTTCAGAGA ATGGATACAA ATCCTGCAAA AAATGTGATA TCAGTTGTTT GACGTGCAAT
    GGCCCAGGAT TCAAGAACTG TACAAGCTGC CCTAGTGGGT ATCTCTTAGA CTTAGGAATG
    TGTCAAATGG GAGCCATTTG CAAGGATGGA GAATATGTTG ATGAGCATGG CCACTGCCAG
    ACCTGTGAGG CCTCATGTGC CAAGTGCCAG GGACCAACCC AGGAAGACTG CACTACCTGC
    CCCATGACAA GGATTTTTGA TGATGGCCGC TGTGTTTCGA ACTGCCCCTC ATGGAAATTT
    GAATTTGAGA ACCAATGCCA TCCATGCCAC CACACCTGCC AGAGATGCCA AGGAAGTGGC
    CCTACCCACT GCACCTCCTG TGGAGCAGAC AACTATGGCC GAGAGCACTT CCTGTACCAG
    GGAGAGTGTG GAGATAGCTG CCCAGAGGGC CACTATGCCA CTGAGGGGAA CACCTGCCTG
    CCCTGCCCAG ACAACTGTGA GCTTTGCCAC AGCGTGCATG TCTGCACAAG ATGCATGAAG
    GGCTACTTCA TAGCGCCCAC CAACCACACA TGCCAGAAGT TAGAGTGTGG ACAAGGTGAA
    GTCCAAGACC CAGACTATGA AGAATGTGTC CCTTGTGAAG AAGGATGTCT GGGATGCAGC
    TTGGATGATC CAGGAACATG TACATCTTGC GCTATGGGGT ATTACAGGTT TGATCACCAT
    TGTTATAAAA CCTGTCCTGA GAAGACCTAC AGTGAGGAAG TGGAATGCAA GGCGTGTGAT
    AGTAACTGTG GCAGCTGTGA CCAGAATGGG TGTTACTGGT GTGAAGAGGG CTTCTTTCTC
    TTAGGTGGCA GTTGTGTGAG GAAATGTGGT CCTGGATTCT ATGGTGACCA AGAAATGGGA
    GAATGTGAGT CCTGCCACCG AGCATGCGAA ACCTGCACAG GCCCTGGTCA TGACGAGTGC
    AGCAGCTGCC AGGAAGGACT GCAGCTGCTG CGTGGGATGT GCGTGCATGC CACCAAGACC
    CAGGAGGAGG GCAAATTCTG GAATGAAGCT GTGTCCACTG CAAACCTATC TGTGGTGAAG
    AGCCTGCTGC AGGAGCGACG AAGGTGGAAA GTTCAAATCA AAAGAGATAT TTTGAGAAAA
    CTCCAGCCTT GTCATTCTTC TTGTAAAACC TGCAATGGAT CTGCAACTCT GTGCACTTCA
    TGTCCCAAAG GTGCATATCT TCTGGCTCAG GCCTGTGTTT CCTCCTGTCC CCAAGGCACA
    TGGCCTTCCG TAAGGAGTGG GAGCTGCGAG AACTGTACGG AGGCCTGTGC CATCTGCTCT
    GGAGCCGATC TTTGCAAAAA ATGCCAGATG CAGCCGGGCC ACCCTCTCTT CCTCCATGAA
    GGCAGGTGCT ACTCCAAGTG CCCGGAGGGC TCTTATGCAG AAGACGGCAT ATGTGAACGC
    TGTAGCTCTC CTTGCAGAAC ATGTGAAGGA AACGCCACCA ACTGCCATTC TTGTGAAGGA
    GGCCACGTCC TGCACCACGG AGTGTGCCAG GAAAACTGCC CCGAGAGGCA CGTGGCTGTG
    AAGGGGGTAT GCAAGCATTG CCCAGAGATG TGTCAGGACT GCATCCATGA GAAAACATGC
    AAAGAGTGCA CGCCTGAGTT CTTCCTGCAC GATGATATGT GCCACCAGTC CTGTCCCCGT
    GGCTTCTATG CAGACTCGCG CCACTGTGTC CCCTGCCATA AAGACTGTCT GGAGTGCAGT
    GGCCCCAAAG CCGACGACTG CGAGCTCTGT CTTGAGAGTT CCTGGGTCCT CTATGATGGA
    CTGTGCTTGG AGGAGTGTCC AGCAGGAACC TATTATGAAA AGGAGACTAA GGAGTGCAGA
    GATTGCCACA AGTCCTGCTT GACCTGCTCA TCATCTGGGA CCTGCACCAC CTGTCAGAAA
    GGCCTGATCA TGAACCCTCG TGGGAGCTGC ATGGCCAACG AGAAGTGCTC ACCCTCCGAG
    TACTGGGATG AGGATGCTCC CGGGTGCAAG CCCTGCCATG TTAAGTGCTT CCACTGCATG
    GGGCCGGCGG AGGACCAGTG TCAAACATGC CCCATGAACA GCCTTCTTCT CAACACAACC
    TGTGTGAAGG ACTGCCCAGA GGGCTATTAT GCCGATGAGG ACAGCAACCG GTGTGCCCAC
    TGCCACAGCT CTTGCAGGAC ATGTGAAGGG AGACACAGCA GGCAGTGCCA CTCCTGCCGA
    CCGGGCTGGT TCCAGCTAGG AAAAGAGTGC CTGCTCCAGT GCAGGGAAGG ATATTACGCA
    GACAACTCCA CTGGCCGGTG TGAGAGGTGC AACAGGAGCT GCAAGGGGTG CCAGGGCCCA
    CGGCCCACAG ACTGCCTGTC TTGCGATAGA TTTTTCTTTC TGCTCCGCTC CAAAGGAGAG
    TGTCATCGCT CCTGCCCAGA CCATTACTAT GTAGAGCAAA GCACACAGAC CTGTGAGAGA
    TGCCATCCGA CTTGTGATCA ATGCAAAGGA AAAGGAGCGT TGAATTGTTT ATCCTGTGTG
    TGGAGTTACC ACCTCATGGG AGGGATCTGC ACCTCGGACT GTCTTGTGGG GGAATACAGA
    GTGGGAGAGG GAGAGAAGTT TAACTGTGAA AAATGCCACG AGAGCTGCAT GGAATGCAAG
    GGACCAGGGG CCAAGAACTG CACCTTGTGC CCTGCCAACC TGGTGCTGCA CATGGACGAC
    AGCCACTGCC TCCACTGCTG CAACACCTCT GATCCCCCCA GTGCCCAGGA GTGCTGTGAC
    TGCCAGGACA CCACGGACGA ATGCATCCTT CGAACAAGCA AGGTTAGGCC TGCAACTGAG
    CATTTCAAGA CAGCTCTGTT CATCACCTCC TCCATGATGC TGGTGCTTCT GCTCGGGGCA
    GCTGTGGTAG TGTGGAAGAA ATCTCGTGGC CGAGTCCAGC CAGCAGCAAA GGCCGGCTAT
    GAAAAACTGG CCGACCCCAA CAAGTCTTAC TCCTCCTATA AGAGCAGCTA TAGAGAGAGC
    ACCAGCTTTG AAGAGGATCA GGTGATTGAG TACAGGGATC GGGACTATGA TGAGGATGAT
    GATGATGACA TCGTCTACAT GGGCCAGGAT GGCACAGTCT ACCGGAAATT TAAATATGGG
    CTGCTGGATG ACGATGACAT AGATGAGCTG GAATATGATG ACGAGAGTTA CTCCTACTAC
    CAGTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.