COPZ2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	COPZ2
Entrez Gene ID	51226
Full Name	coatomer protein complex subunit zeta 2
Synonyms	zeta2-COP
General protein information	Preferred Names coatomer protein complex subunit zeta 2 Names coatomer subunit zeta-2 nonclathrin coat protein zeta-COP zeta-2 COP zeta-2-coat protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q21.32
Summary	This gene encodes a member of the adaptor complexes small subunit family. The encoded protein is a subunit of the coatomer protein complex, a seven-subunit complex that functions in the formation of COPI-type, non-clathrin-coated vesicles. COPI vesicles function in the retrograde Golgi-to-ER transport of dilysine-tagged proteins. [provided by RefSeq, Feb 2014].
Disorder MIM:	615526

mRNA and Protein(s)

mRNA	Protein	Name
NM_016429.4	NP_057513.1	coatomer subunit zeta-2
NM_016429.3	NP_057513.1	coatomer subunit zeta-2
XM_011524874.2	XP_011523176.1	coatomer subunit zeta-2 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	COPZ2	XP_003954507.1
Rattus norvegicus (Norway rat)	Copz2	NP_001101764.1
Danio rerio (zebrafish)	copz2	NP_571582.1
Homo sapiens (human)	COPZ2	NP_057513.1
Canis lupus familiaris (dog)	COPZ2	XP_005624668.1
Bos taurus (cattle)	COPZ2	NP_001193850.1
	COPZ2	XP_001084942.1
Mus musculus (house mouse)	Copz2	NP_063930.1

Gene Ontology
Bibliography

Related articles in PubMed

Genome-wide association analysis of genetic generalized epilepsies implicates susceptibility loci at 1q43, 2p16.1, 2q22.3 and 17q21.32.
, , Steffens M, Leu C, Ruppert AK, Zara F, Striano P, Robbiano A, Capovilla G, Tinuper P, Gambardella A, Bianchi A, La Neve A, Crichiutti G, de Kovel CG, Kasteleijn-Nolst Trenit? D, de Haan GJ, Lindhout D, Gaus V, Schmitz B, Janz D, Weber YG, Becker F, Lerche H, Steinhoff BJ, Kleefu?-Lie AA, Kunz WS, Surges R, Elger CE, Muhle H, von Spiczak S, Ostertag P, Helbig I, Stephani U, M?ller RS, Hjalgrim H, Dibbens LM, Bellows S, Oliver K, Mullen S, Scheffer IE, Berkovic SF, Everett KV, Gardiner MR, Marini C, Guerrini R, Lehesjoki AE, Siren A, Guipponi M, Malafosse A, Thomas P, Nabbout R, Baulac S, Leguern E, Guerrero R, Serratosa JM, Reif PS, Rosenow F, M?rzinger M, Feucht M, Zimprich F, Kapser C, Schankin CJ, Suls A, Smets K, De Jonghe P, Jordanova A, Caglayan H, Yapici Z, Yalcin DA, Baykan B, Bebek N, Ozbek U, Gieger C, Wichmann HE, Balschun T, Ellinghaus D, Franke A, Meesters C, Becker T, Wienker TF, Hempelmann A, Schulz H, R?schendorf F, Leber M, Pauck SM, Trucks H, Toliat MR, N?rnberg P, Avanzini G, Koeleman BP, Sander T
Human molecular genetics21(24)5359-72(2012 Dec)

Tumor-specific silencing of COPZ2 gene encoding coatomer protein complex subunit ? 2 renders tumor cells dependent on its paralogous gene COPZ1.
Shtutman M, Baig M, Levina E, Hurteau G, Lim CU, Broude E, Nikiforov M, Harkins TT, Carmack CS, Ding Y, Wieland F, Buttyan R, Roninson IB
Proceedings of the National Academy of Sciences of the United States of America108(30)12449-54(2011 Jul)

Solution structure of human zeta-COP: direct evidences for structural similarity between COP I and clathrin-adaptor coats.
Yu W, Lin J, Jin C, Xia B
Journal of molecular biology386(4)903-12(2009 Mar)

Novel isotypic gamma/zeta subunits reveal three coatomer complexes in mammals.
Wegmann D, Hess P, Baier C, Wieland FT, Reinhard C
Molecular and cellular biology24(3)1070-80(2004 Feb)

Identification and characterization of novel isoforms of COP I subunits.
Futatsumori M, Kasai K, Takatsu H, Shin HW, Nakayama K
Journal of biochemistry128(5)793-801(2000 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The knockdown of COPZ1, but not of COPZ2 encoding isoform coatomer protein complex zeta2, caused Golgi apparatus collapse, blocked autophagy, and induced apoptosis in both proliferating and nondividing tumor cells.
Title: Tumor-specific silencing of COPZ2 gene encoding coatomer protein complex subunit ? 2 renders tumor cells dependent on its paralogous gene COPZ1.

The solution structure of a truncated form (residues 1-149; zeta-COP149) of human zeta-COP (total 177 residues), is reported.
Title: Solution structure of human zeta-COP: direct evidences for structural similarity between COP I and clathrin-adaptor coats.

The following COPZ2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the COPZ2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu23368	NM_016429.4 Latest version!	Homo sapiens COPI coat complex subunit zeta 2 (COPZ2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu67778	XM_011524874.2 Latest version!	Homo sapiens COPI coat complex subunit zeta 2 (COPZ2), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
View Old Accession Versions >>
OHu23368	NM_016429.3	Homo sapiens coatomer protein complex subunit zeta 2 (COPZ2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

COPZ2 ( NM_016429.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_057513.1 Homo sapiens COPI coat complex subunit zeta 2 (COPZ2), mRNA.

Price & Availability↑

CloneID	OHu23368
Clone ID Related Accession (Same CDS sequence)	NM_016429.4 , NM_016429.3
Accession Version	NM_016429.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 633bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-28
Organism	Homo sapiens(human)
Product	coatomer subunit zeta-2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY179834.1, BC015924.1 and BQ002984.1. On Nov 23, 2018 this sequence version replaced NM_016429.3. ##Evidence-Data-START## Transcript exon combination :: ERR279874.4501.1, AB037938.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000621465.5/ ENSP00000480707.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCAGCGGC CCGAGGCCTG GCCACGTCCG CACCCGGGGG AGGGGGCCGC GGCGGCCCAG 
GCCGGGGGCC CGGCGCCGCC TGCTCGAGCC GGGGAGCCCT CGGGGCTGCG GTTGCAGGAA 
CCTTCCCTCT ACACCATCAA GGCTGTTTTC ATCCTAGATA ATGACGGGCG CCGGCTGCTG 
GCCAAGTATT ATGATGACAC ATTCCCCTCC ATGAAGGAGC AGATGGTTTT CGAGAAAAAT 
GTCTTCAACA AGACCAGCCG GACTGAGAGT GAGATTGCAT TTTTTGGGGG TATGACCATC 
GTCTACAAGA ACAGCATTGA CCTCTTCCTA TACGTGGTGG GCTCATCCTA CGAGAATGAG 
CTGATGCTCA TGTCTGTTCT CACCTGCCTG TTTGAGTCTC TGAACCACAT GTTAAGGAAG 
AACGTGGAGA AGCGCTGGTT GCTGGAGAAC ATGGACGGAG CCTTCTTGGT GCTGGACGAG 
ATTGTGGATG GCGGTGTGAT TCTGGAGAGT GACCCCCAGC AAGTGATCCA GAAGGTGAAT 
TTTAGGGCAG ATGATGGCGG CTTGACTGAA CAGAGTGTGG CCCAGGTTCT TCAGTCTGCC 
AAGGAACAAA TTAAATGGTC GTTATTGAAA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057513.1
CDS	21..653
Translation	MQRPEAWPRPHPGEGAAAAQAGGPAPPARAGEPSGLRLQEPSLYTIKAVFILDNDGRRLLAKYYDDTFPSMKEQMVFEKNVFNKTSRTESEIAFFGGMTIVYKNSIDLFLYVVGSSYENELMLMSVLTCLFESLNHMLRKNVEKRWLLENMDGAFLVLDEIVDGGVILESDPQQVIQKVNFRADDGGLTEQSVAQVLQSAKEQIKWSLLK

Target ORF information:

RefSeq Version	NM_016429.4
Organism	Homo sapiens(human)
Definition	Homo sapiens COPI coat complex subunit zeta 2 (COPZ2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016429.4

ORF Insert Sequence:

ATGCAGCGGC CCGAGGCCTG GCCACGTCCG CACCCGGGGG AGGGGGCCGC GGCGGCCCAG 
GCCGGGGGCC CGGCGCCGCC TGCTCGAGCC GGGGAGCCCT CGGGGCTGCG GTTGCAGGAA 
CCTTCCCTCT ACACCATCAA GGCTGTTTTC ATCCTAGATA ATGACGGGCG CCGGCTGCTG 
GCCAAGTATT ATGATGACAC ATTCCCCTCC ATGAAGGAGC AGATGGTTTT CGAGAAAAAT 
GTCTTCAACA AGACCAGCCG GACTGAGAGT GAGATTGCAT TTTTTGGGGG TATGACCATC 
GTCTACAAGA ACAGCATTGA CCTCTTCCTA TACGTGGTGG GCTCATCCTA CGAGAATGAG 
CTGATGCTCA TGTCTGTTCT CACCTGCCTG TTTGAGTCTC TGAACCACAT GTTAAGGAAG 
AACGTGGAGA AGCGCTGGTT GCTGGAGAAC ATGGACGGAG CCTTCTTGGT GCTGGACGAG 
ATTGTGGATG GCGGTGTGAT TCTGGAGAGT GACCCCCAGC AAGTGATCCA GAAGGTGAAT 
TTTAGGGCAG ATGATGGCGG CTTGACTGAA CAGAGTGTGG CCCAGGTTCT TCAGTCTGCC 
AAGGAACAAA TTAAATGGTC GTTATTGAAA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

COPZ2 ( NM_016429.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_057513.1 Homo sapiens coatomer protein complex subunit zeta 2 (COPZ2), mRNA.

Price & Availability↑

CloneID	OHu23368
Clone ID Related Accession (Same CDS sequence)	NM_016429.4 , NM_016429.3
Accession Version	NM_016429.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 633bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	coatomer subunit zeta-2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY179834.1, BC015924.1 and BQ002984.1. On Feb 26, 2014 this sequence version replaced NM_016429.2. ##Evidence-Data-START## Transcript exon combination :: ERR279874.4501.1, AB047849.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAGCGGC CCGAGGCCTG GCCACGTCCG CACCCGGGGG AGGGGGCCGC GGCGGCCCAG 
GCCGGGGGCC CGGCGCCGCC TGCTCGAGCC GGGGAGCCCT CGGGGCTGCG GTTGCAGGAA 
CCTTCCCTCT ACACCATCAA GGCTGTTTTC ATCCTAGATA ATGACGGGCG CCGGCTGCTG 
GCCAAGTATT ATGATGACAC ATTCCCCTCC ATGAAGGAGC AGATGGTTTT CGAGAAAAAT 
GTCTTCAACA AGACCAGCCG GACTGAGAGT GAGATTGCAT TTTTTGGGGG TATGACCATC 
GTCTACAAGA ACAGCATTGA CCTCTTCCTA TACGTGGTGG GCTCATCCTA CGAGAATGAG 
CTGATGCTCA TGTCTGTTCT CACCTGCCTG TTTGAGTCTC TGAACCACAT GTTAAGGAAG 
AACGTGGAGA AGCGCTGGTT GCTGGAGAAC ATGGACGGAG CCTTCTTGGT GCTGGACGAG 
ATTGTGGATG GCGGTGTGAT TCTGGAGAGT GACCCCCAGC AAGTGATCCA GAAGGTGAAT 
TTTAGGGCAG ATGATGGCGG CTTGACTGAA CAGAGTGTGG CCCAGGTTCT TCAGTCTGCC 
AAGGAACAAA TTAAATGGTC GTTATTGAAA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057513.1
CDS	30..662
Translation	MQRPEAWPRPHPGEGAAAAQAGGPAPPARAGEPSGLRLQEPSLYTIKAVFILDNDGRRLLAKYYDDTFPSMKEQMVFEKNVFNKTSRTESEIAFFGGMTIVYKNSIDLFLYVVGSSYENELMLMSVLTCLFESLNHMLRKNVEKRWLLENMDGAFLVLDEIVDGGVILESDPQQVIQKVNFRADDGGLTEQSVAQVLQSAKEQIKWSLLK

Target ORF information:

RefSeq Version	NM_016429.3
Organism	Homo sapiens(human)
Definition	Homo sapiens coatomer protein complex subunit zeta 2 (COPZ2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016429.3

ORF Insert Sequence:

ATGCAGCGGC CCGAGGCCTG GCCACGTCCG CACCCGGGGG AGGGGGCCGC GGCGGCCCAG 
GCCGGGGGCC CGGCGCCGCC TGCTCGAGCC GGGGAGCCCT CGGGGCTGCG GTTGCAGGAA 
CCTTCCCTCT ACACCATCAA GGCTGTTTTC ATCCTAGATA ATGACGGGCG CCGGCTGCTG 
GCCAAGTATT ATGATGACAC ATTCCCCTCC ATGAAGGAGC AGATGGTTTT CGAGAAAAAT 
GTCTTCAACA AGACCAGCCG GACTGAGAGT GAGATTGCAT TTTTTGGGGG TATGACCATC 
GTCTACAAGA ACAGCATTGA CCTCTTCCTA TACGTGGTGG GCTCATCCTA CGAGAATGAG 
CTGATGCTCA TGTCTGTTCT CACCTGCCTG TTTGAGTCTC TGAACCACAT GTTAAGGAAG 
AACGTGGAGA AGCGCTGGTT GCTGGAGAAC ATGGACGGAG CCTTCTTGGT GCTGGACGAG 
ATTGTGGATG GCGGTGTGAT TCTGGAGAGT GACCCCCAGC AAGTGATCCA GAAGGTGAAT 
TTTAGGGCAG ATGATGGCGG CTTGACTGAA CAGAGTGTGG CCCAGGTTCT TCAGTCTGCC 
AAGGAACAAA TTAAATGGTC GTTATTGAAA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

COPZ2 ( XM_011524874.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011523176.1 Homo sapiens COPI coat complex subunit zeta 2 (COPZ2), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu67778
Clone ID Related Accession (Same CDS sequence)	XM_011524874.2
Accession Version	XM_011524874.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 555bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	coatomer subunit zeta-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011524874.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGCGGC CCGAGGCCTG GCCACGTCCG CACCCGGGGG AGGGGGCCGC GGCGGCCCAG 
GCCGGGGGCC CGGCGCCGCC TGCTCGAGCC GGGGAGCCCT CGGGGCTGCG GTTGCAGGAA 
CCTTCCCTCT ACACCATCAA GGCTGTTTTC ATCCTAGATA ATGACGGGCG CCGGCTGCTG 
GCCAAGTATT ATGATGACAC ATTCCCCTCC ATGAAGGAGC AGATGGTTTT CGAGAAAAAT 
GTCTTCAACA AGACCAGCCG GACTGAGAGT GAGATTGCAT TTTTTGGGGG TATGACCATC 
GTCTACAAGA ACAGCATTGA CCTCTTCCTA TACGTGGTGG GCTCATCCTA CGAGAATGAG 
CTGATGCTCA TGTCTGTTCT CACCTGCCTG TTTGAGTCTC TGAACCACAT GTTAAGTGTG 
ATTCTGGAGA GTGACCCCCA GCAAGTGATC CAGAAGGTGA ATTTTAGGGC AGATGATGGC 
GGCTTGACTG AACAGAGTGT GGCCCAGGTT CTTCAGTCTG CCAAGGAACA AATTAAATGG 
TCGTTATTGA AATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011523176.1
CDS	29..583
Translation	MQRPEAWPRPHPGEGAAAAQAGGPAPPARAGEPSGLRLQEPSLYTIKAVFILDNDGRRLLAKYYDDTFPSMKEQMVFEKNVFNKTSRTESEIAFFGGMTIVYKNSIDLFLYVVGSSYENELMLMSVLTCLFESLNHMLSVILESDPQQVIQKVNFRADDGGLTEQSVAQVLQSAKEQIKWSLLK

Target ORF information:

RefSeq Version	XM_011524874.2
Organism	Homo sapiens(human)
Definition	Homo sapiens COPI coat complex subunit zeta 2 (COPZ2), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011524874.2

ORF Insert Sequence:

ATGCAGCGGC CCGAGGCCTG GCCACGTCCG CACCCGGGGG AGGGGGCCGC GGCGGCCCAG 
GCCGGGGGCC CGGCGCCGCC TGCTCGAGCC GGGGAGCCCT CGGGGCTGCG GTTGCAGGAA 
CCTTCCCTCT ACACCATCAA GGCTGTTTTC ATCCTAGATA ATGACGGGCG CCGGCTGCTG 
GCCAAGTATT ATGATGACAC ATTCCCCTCC ATGAAGGAGC AGATGGTTTT CGAGAAAAAT 
GTCTTCAACA AGACCAGCCG GACTGAGAGT GAGATTGCAT TTTTTGGGGG TATGACCATC 
GTCTACAAGA ACAGCATTGA CCTCTTCCTA TACGTGGTGG GCTCATCCTA CGAGAATGAG 
CTGATGCTCA TGTCTGTTCT CACCTGCCTG TTTGAGTCTC TGAACCACAT GTTAAGTGTG 
ATTCTGGAGA GTGACCCCCA GCAAGTGATC CAGAAGGTGA ATTTTAGGGC AGATGATGGC 
GGCTTGACTG AACAGAGTGT GGCCCAGGTT CTTCAGTCTG CCAAGGAACA AATTAAATGG 
TCGTTATTGA AATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genome-wide association analysis of genetic generalized epilepsies implicates susceptibility loci at 1q43, 2p16.1, 2q22.3 and 17q21.32.
Human molecular genetics21(24)5359-72(2012 Dec)
,,Steffens M,Leu C,Ruppert AK,Zara F,Striano P,Robbiano A,Capovilla G,Tinuper P,Gambardella A,Bianchi A,La Neve A,Crichiutti G,de Kovel CG,Kasteleijn-Nolst Trenit? D,de Haan GJ,Lindhout D,Gaus V,Schmitz B,Janz D,Weber YG,Becker F,Lerche H,Steinhoff BJ,Kleefu?-Lie AA,Kunz WS,Surges R,Elger CE,Muhle H,von Spiczak S,Ostertag P,Helbig I,Stephani U,M?ller RS,Hjalgrim H,Dibbens LM,Bellows S,Oliver K,Mullen S,Scheffer IE,Berkovic SF,Everett KV,Gardiner MR,Marini C,Guerrini R,Lehesjoki AE,Siren A,Guipponi M,Malafosse A,Thomas P,Nabbout R,Baulac S,Leguern E,Guerrero R,Serratosa JM,Reif PS,Rosenow F,M?rzinger M,Feucht M,Zimprich F,Kapser C,Schankin CJ,Suls A,Smets K,De Jonghe P,Jordanova A,Caglayan H,Yapici Z,Yalcin DA,Baykan B,Bebek N,Ozbek U,Gieger C,Wichmann HE,Balschun T,Ellinghaus D,Franke A,Meesters C,Becker T,Wienker TF,Hempelmann A,Schulz H,R?schendorf F,Leber M,Pauck SM,Trucks H,Toliat MR,N?rnberg P,Avanzini G,Koeleman BP,Sander T

Tumor-specific silencing of COPZ2 gene encoding coatomer protein complex subunit ? 2 renders tumor cells dependent on its paralogous gene COPZ1.
Proceedings of the National Academy of Sciences of the United States of America108(30)12449-54(2011 Jul)
Shtutman M,Baig M,Levina E,Hurteau G,Lim CU,Broude E,Nikiforov M,Harkins TT,Carmack CS,Ding Y,Wieland F,Buttyan R,Roninson IB

Solution structure of human zeta-COP: direct evidences for structural similarity between COP I and clathrin-adaptor coats.
Journal of molecular biology386(4)903-12(2009 Mar)
Yu W,Lin J,Jin C,Xia B

Novel isotypic gamma/zeta subunits reveal three coatomer complexes in mammals.
Molecular and cellular biology24(3)1070-80(2004 Feb)
Wegmann D,Hess P,Baier C,Wieland FT,Reinhard C

Identification and characterization of novel isoforms of COP I subunits.
Journal of biochemistry128(5)793-801(2000 Nov)
Futatsumori M,Kasai K,Takatsu H,Shin HW,Nakayama K

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COPZ2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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