IMPG2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	IMPG2
Entrez Gene ID	50939
Full Name	interphotoreceptor matrix proteoglycan 2
Synonyms	IPM200,RP56,SPACRCAN,VMD5
General protein information	Preferred Names interphotoreceptor matrix proteoglycan 2 Names interphotoreceptor matrix proteoglycan 2 IPM 200 interphotoreceptor matrix proteoglycan IPM 200 interphotoreceptor matrix proteoglycan of 200 kDa sialoprotein associated with cones and rods proteoglycan
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 3 Map Location: 3q12.3
Summary	The protein encoded by this gene binds chondroitin sulfate and hyaluronan and is a proteoglycan. The encoded protein plays a role in the organization of the interphotoreceptor matrix and may promote the growth and maintenance of the light-sensitive photoreceptor outer segment. Defects in this gene are a cause of retinitis pigmentosa type 56 and maculopathy, IMPG2-related.[provided by RefSeq, Mar 2011].
Disorder MIM:	607056
Disorder Html:	Retinitis pigmentosa 56, 613581 (3); Macular dystrophy, vitelliform, 5, 616152 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_016247.3	NP_057331.2	interphotoreceptor matrix proteoglycan 2 precursor
NM_016247.4	NP_057331.2	interphotoreceptor matrix proteoglycan 2 precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	IMPG2	XP_005639477.1
Pan troglodytes (chimpanzee)	IMPG2	XP_516627.2
Mus musculus (house mouse)	Impg2	NP_777365.2
Gallus gallus (chicken)	IMPG2	NP_001038104.1
Homo sapiens (human)	IMPG2	NP_057331.2
	IMPG2	XP_001095760.1
Bos taurus (cattle)	IMPG2	XP_002684765.3
Rattus norvegicus (Norway rat)	Impg2	NP_620788.2

Gene Ontology
Bibliography

Related articles in PubMed

Frequency and clinical pattern of vitelliform macular dystrophy caused by mutations of interphotoreceptor matrix IMPG1 and IMPG2 genes.
Meunier I, Manes G, Bocquet B, Marquette V, Baudoin C, Puech B, Defoort-Dhellemmes S, Audo I, Verdet R, Arndt C, Zanlonghi X, Le Meur G, Dhaenens CM, Hamel CP
Ophthalmology121(12)2406-14(2014 Dec)

IMPG2-associated retinitis pigmentosa displays relatively early macular involvement.
van Huet RA, Collin RW, Siemiatkowska AM, Klaver CC, Hoyng CB, Simonelli F, Khan MI, Qamar R, Banin E, Cremers FP, Theelen T, den Hollander AI, van den Born LI, Klevering BJ
Investigative ophthalmology & visual science55(6)3939-53(2014 May)

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.
Ghai R, Bugarcic A, Liu H, Norwood SJ, Skeldal S, Coulson EJ, Li SS, Teasdale RD, Collins BM
Proceedings of the National Academy of Sciences of the United States of America110(8)E643-52(2013 Feb)

Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method.
Oshikawa M, Tsutsui C, Ikegami T, Fuchida Y, Matsubara M, Toyama S, Usami R, Ohtoko K, Kato S
Investigative ophthalmology & visual science52(9)6662-70(2011 Aug)

Mutations in IMPG2, encoding interphotoreceptor matrix proteoglycan 2, cause autosomal-recessive retinitis pigmentosa.
Bandah-Rozenfeld D, Collin RW, Banin E, van den Born LI, Coene KL, Siemiatkowska AM, Zelinger L, Khan MI, Lefeber DJ, Erdinest I, Testa F, Simonelli F, Voesenek K, Blokland EA, Strom TM, Klaver CC, Qamar R, Banfi S, Cremers FP, Sharon D, den Hollander AI
American journal of human genetics87(2)199-208(2010 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

IMPG1 and IMPG2 are new causal genes of vitelliform dystrophy, involved in 8% of our families.
Title: Frequency and clinical pattern of vitelliform macular dystrophy caused by mutations of interphotoreceptor matrix IMPG1 and IMPG2 genes.

Mutations in IMPG2 cause a severe form of retinitis pigmentosa with symptoms manifesting in the first 2 decades of life.
Title: IMPG2-associated retinitis pigmentosa displays relatively early macular involvement.

identification of IMPG2 mutations in autosomal-recessive retinitis pigmentosa; data show that mutations in a structural component of the interphotoreceptor matrix can cause autosomal-recessive retinitis pigmentosa
Title: Mutations in IMPG2, encoding interphotoreceptor matrix proteoglycan 2, cause autosomal-recessive retinitis pigmentosa.

IPM 200 represents the second member of a novel family of retinal proteoglycans suspected to be involved in retinal adhesion and photoreceptor cell survival
Title: Molecular characterization and genomic mapping of human IPM 200, a second member of a novel family of proteoglycans.

The following IMPG2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IMPG2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu20511	NM_016247.4 Latest version!	Homo sapiens interphotoreceptor matrix proteoglycan 2 (IMPG2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$643.30 $919.00
View Old Accession Versions >>
OHu20511	NM_016247.3	Homo sapiens interphotoreceptor matrix proteoglycan 2 (IMPG2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$643.30 $919.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IMPG2 ( NM_016247.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_057331.2 Homo sapiens interphotoreceptor matrix proteoglycan 2 (IMPG2), mRNA.

Price & Availability↑

CloneID	OHu20511
Clone ID Related Accession (Same CDS sequence)	NM_016247.3 , NM_016247.4
Accession Version	NM_016247.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3726bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	interphotoreceptor matrix proteoglycan 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX953286.1, AB593127.1, AC093008.10 and BM671068.1. This sequence is a reference standard in the RefSeqGene project. On Apr 1, 2011 this sequence version replaced NM_016247.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AB593127.1, AF173155.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATTATGT TTCCTCTTTT TGGGAAGATT TCTCTGGGTA TTTTGATATT TGTCCTGATA 
GAAGGAGACT TTCCATCATT AACAGCACAA ACCTACTTAT CTATAGAGGA GATCCAAGAA 
CCCAAGAGTG CAGTTTCTTT TCTCCTGCCT GAAGAATCAA CAGACCTTTC TCTAGCTACC 
AAAAAGAAAC AGCCTCTGGA CCGCAGAGAA ACTGAAAGAC AGTGGTTAAT CAGAAGGCGG 
AGATCTATTC TGTTTCCTAA TGGAGTGAAA ATCTGCCCAG ATGAAAGTGT TGCAGAGGCT 
GTGGCAAATC ATGTGAAGTA TTTTAAAGTC CGAGTGTGTC AGGAAGCTGT CTGGGAAGCC 
TTCAGGACTT TTTGGGATCG ACTTCCTGGG CGTGAGGAAT ATCATTACTG GATGAATTTG 
TGTGAGGATG GAGTCACAAG TATATTTGAA ATGGGCACAA ATTTTAGTGA ATCTGTGGAA 
CATAGAAGCT TAATCATGAA GAAACTGACT TATGCAAAGG AAACTGTAAG CAGCTCTGAA 
CTGTCTTCTC CAGTTCCTGT TGGTGATACT TCAACATTGG GAGACACTAC TCTCAGTGTT 
CCACATCCAG AGGTGGACGC CTATGAAGGT GCCTCAGAGA GCAGCTTGGA AAGGCCAGAG 
GAGAGTATTA GCAATGAAAT TGAGAATGTG ATAGAAGAAG CCACAAAACC AGCAGGTGAA 
CAGATTGCAG AATTCAGTAT CCACCTTTTG GGGAAGCAGT ACAGGGAAGA ACTACAGGAT 
TCCTCCAGCT TTCACCACCA GCACCTTGAA GAAGAATTTA TTTCAGAGGT TGAAAATGCA 
TTTACTGGGT TACCAGGCTA CAAGGAAATT CGTGTACTTG AATTTAGGTC CCCCAAGGAA 
AATGACAGTG GCGTAGATGT TTACTATGCA GTTACCTTCA ATGGTGAGGC CATCAGCAAT 
ACCACCTGGG ACCTCATTAG CCTTCACTCC AACAAGGTGG AAAACCATGG CCTTGTGGAA 
CTGGATGATA AACCCACTGT TGTTTATACA ATCAGTAACT TCAGAGATTA TATTGCTGAG 
ACATTGCAGC AGAATTTTTT GCTGGGGAAC TCTTCCTTGA ATCCAGATCC TGATTCCCTG 
CAGCTTATCA ATGTGAGAGG AGTTTTGCGT CACCAAACTG AAGATCTAGT TTGGAACACC 
CAAAGTTCAA GTCTTCAGGC AACGCCGTCA TCTATTCTGG ATAATACCTT TCAAGCTGCA 
TGGCCCTCAG CAGATGAATC CATCACCAGC AGTATTCCAC CACTTGATTT CAGCTCTGGT 
CCTCCCTCAG CCACTGGCAG GGAACTCTGG TCAGAAAGTC CTTTGGGTGA TTTAGTGTCT 
ACACACAAAT TAGCCTTTCC CTCGAAGATG GGCCTCAGCT CTTCCCCAGA GGTTTTAGAG 
GTTAGCAGCT TGACTCTTCA TTCTGTCACC CCGGCAGTGC TTCAGACTGG CTTGCCTGTG 
GCTTCTGAGG AAAGGACTTC TGGATCTCAC TTGGTAGAAG ATGGATTAGC CAATGTTGAA 
GAGTCAGAAG ATTTTCTTTC TATTGATTCA TTGCCTTCAA GTTCATTCAC TCAACCTGTG 
CCAAAAGAAA CAATACCATC CATGGAAGAC TCTGATGTGT CCTTAACATC TTCACCATAT 
CTGACCTCTT CTATACCTTT TGGCTTGGAC TCCTTGACCT CCAAAGTCAA AGACCAATTA 
AAAGTGAGCC CTTTCCTGCC AGATGCATCC ATGGAAAAAG AGTTAATATT TGACGGTGGT 
TTAGGTTCAG GGTCTGGGCA AAAGGTAGAT CTGATTACTT GGCCATGGAG TGAGACTTCA 
TCAGAGAAGA GCGCTGAACC ACTGTCCAAG CCGTGGCTTG AAGATGATGA TTCACTTTTG 
CCAGCTGAGA TTGAAGACAA GAAACTAGTT TTAGTTGACA AAATGGATTC CACAGACCAA 
ATTAGTAAGC ACTCAAAATA TGAACATGAT GACAGATCCA CACACTTTCC AGAGGAAGAG 
CCTCTTAGTG GGCCTGCTGT GCCCATCTTC GCAGATACTG CAGCTGAATC TGCGTCTCTA 
ACCCTCCCCA AGCACATATC AGAAGTACCT GGTGTTGATG ATTACTCAGT TACCAAAGCA 
CCTCTTATAC TGACATCTGT AGCAATCTCT GCCTCTACTG ATAAATCAGA TCAGGCAGAT 
GCCATCCTAA GGGAGGATAT GGAACAAATT ACTGAGTCAT CCAACTATGA ATGGTTTGAC 
AGTGAGGTTT CAATGGTAAA GCCAGATATG CAAACTTTGT GGACTATATT GCCAGAATCA 
GAGAGAGTTT GGACAAGAAC TTCTTCCCTA GAGAAATTGT CCAGAGACAT ATTGGCAAGT 
ACACCACAGA GTGCTGACAG GCTCTGGTTA TCTGTGACAC AGTCTACCAA ATTGCCTCCA 
ACCACAATCT CCACCCTGCT AGAGGATGAA GTAATTATGG GTGTACAGGA TATTTCGTTA 
GAACTGGACC GGATAGGCAC AGATTACTAT CAGCCTGAGC AAGTCCAAGA GCAAAATGGC 
AAGGTTGGTA GTTATGTGGA AATGTCAACA AGTGTTCACT CCACAGAGAT GGTTAGTGTG 
GCTTGGCCCA CAGAAGGAGG AGATGACTTG AGTTATACCC AGACTTCAGG AGCTTTGGTG 
GTTTTCTTCA GCCTCCGAGT GACTAACATG ATGTTTTCAG AAGATCTGTT TAATAAAAAC 
TCCTTGGAGT ATAAAGCCCT GGAGCAAAGA TTCTTAGAAT TGCTGGTTCC CTATCTCCAG 
TCAAATCTCA CGGGGTTCCA GAACTTAGAA ATCCTCAACT TCAGAAATGG CAGCATTGTG 
GTGAACAGTC GAATGAAGTT TGCCAATTCT GTCCCTCCTA ACGTCAACAA TGCGGTGTAC 
ATGATTCTGG AAGACTTTTG TACCACTGCC TACAATACCA TGAACTTGGC TATTGATAAA 
TACTCTCTTG ATGTGGAATC AGGTGATGAA GCCAACCCTT GCAAGTTTCA GGCCTGTAAT 
GAATTTTCAG AGTGTCTGGT CAACCCCTGG AGTGGAGAAG CAAAGTGCAG ATGCTTCCCT 
GGATACCTGA GTGTGGAAGA ACGGCCCTGT CAGAGTCTCT GTGACCTACA GCCTGACTTC 
TGCTTGAATG ATGGAAAGTG TGACATTATG CCTGGGCACG GGGCCATTTG TAGGTGCCGG 
GTGGGTGAGA ACTGGTGGTA CCGAGGCAAG CACTGTGAGG AATTTGTGTC TGAGCCCGTG 
ATCATAGGCA TCACTATTGC CTCCGTGGTT GGACTTCTTG TCATCTTTTC TGCTATCATC 
TACTTCTTCA TCAGGACTCT CCAAGCACAC CATGACAGGA GTGAAAGAGA GAGTCCCTTC 
AGTGGCTCCA GCAGGCAGCC TGACAGCCTC TCATCTATTG AGAATGCTGT GAAGTACAAC 
CCCGTGTATG AAAGTCACAG GGCTGGATGT GAGAAGTATG AGGGACCCTA TCCTCAGCAT 
CCCTTCTACA GCTCTGCTAG CGGAGACGTG ATTGGTGGGC TGAGCAGAGA AGAAATCAGA 
CAGATGTATG AGAGCAGTGA GCTTTCCAGA GAGGAAATTC AAGAGAGAAT GAGAGTTTTG 
GAACTGTATG CCAATGATCC TGAGTTTGCA GCTTTTGTGA GAGAGCAACA AGTGGAAGAG 
GTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057331.2
CDS	204..3929
Translation	MIMFPLFGKISLGILIFVLIEGDFPSLTAQTYLSIEEIQEPKSAVSFLLPEESTDLSLATKKKQPLDRRETERQWLIRRRRSILFPNGVKICPDESVAEAVANHVKYFKVRVCQEAVWEAFRTFWDRLPGREEYHYWMNLCEDGVTSIFEMGTNFSESVEHRSLIMKKLTYAKETVSSSELSSPVPVGDTSTLGDTTLSVPHPEVDAYEGASESSLERPEESISNEIENVIEEATKPAGEQIAEFSIHLLGKQYREELQDSSSFHHQHLEEEFISEVENAFTGLPGYKEIRVLEFRSPKENDSGVDVYYAVTFNGEAISNTTWDLISLHSNKVENHGLVELDDKPTVVYTISNFRDYIAETLQQNFLLGNSSLNPDPDSLQLINVRGVLRHQTEDLVWNTQSSSLQATPSSILDNTFQAAWPSADESITSSIPPLDFSSGPPSATGRELWSESPLGDLVSTHKLAFPSKMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESEDFLSIDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLTSKVKDQLKVSPFLPDASMEKELIFDGGLGSGSGQKVDLITWPWSETSSEKSAEPLSKPWLEDDDSLLPAEIEDKKLVLVDKMDSTDQISKHSKYEHDDRSTHFPEEEPLSGPAVPIFADTAAESASLTLPKHISEVPGVDDYSVTKAPLILTSVAISASTDKSDQADAILREDMEQITESSNYEWFDSEVSMVKPDMQTLWTILPESERVWTRTSSLEKLSRDILASTPQSADRLWLSVTQSTKLPPTTISTLLEDEVIMGVQDISLELDRIGTDYYQPEQVQEQNGKVGSYVEMSTSVHSTEMVSVAWPTEGGDDLSYTQTSGALVVFFSLRVTNMMFSEDLFNKNSLEYKALEQRFLELLVPYLQSNLTGFQNLEILNFRNGSIVVNSRMKFANSVPPNVNNAVYMILEDFCTTAYNTMNLAIDKYSLDVESGDEANPCKFQACNEFSECLVNPWSGEAKCRCFPGYLSVEERPCQSLCDLQPDFCLNDGKCDIMPGHGAICRCRVGENWWYRGKHCEEFVSEPVIIGITIASVVGLLVIFSAIIYFFIRTLQAHHDRSERESPFSGSSRQPDSLSSIENAVKYNPVYESHRAGCEKYEGPYPQHPFYSSASGDVIGGLSREEIRQMYESSELSREEIQERMRVLELYANDPEFAAFVREQQVEEV

Target ORF information:

RefSeq Version	NM_016247.3
Organism	Homo sapiens(human)
Definition	Homo sapiens interphotoreceptor matrix proteoglycan 2 (IMPG2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016247.3

ORF Insert Sequence:

ATGATTATGT TTCCTCTTTT TGGGAAGATT TCTCTGGGTA TTTTGATATT TGTCCTGATA 
GAAGGAGACT TTCCATCATT AACAGCACAA ACCTACTTAT CTATAGAGGA GATCCAAGAA 
CCCAAGAGTG CAGTTTCTTT TCTCCTGCCT GAAGAATCAA CAGACCTTTC TCTAGCTACC 
AAAAAGAAAC AGCCTCTGGA CCGCAGAGAA ACTGAAAGAC AGTGGTTAAT CAGAAGGCGG 
AGATCTATTC TGTTTCCTAA TGGAGTGAAA ATCTGCCCAG ATGAAAGTGT TGCAGAGGCT 
GTGGCAAATC ATGTGAAGTA TTTTAAAGTC CGAGTGTGTC AGGAAGCTGT CTGGGAAGCC 
TTCAGGACTT TTTGGGATCG ACTTCCTGGG CGTGAGGAAT ATCATTACTG GATGAATTTG 
TGTGAGGATG GAGTCACAAG TATATTTGAA ATGGGCACAA ATTTTAGTGA ATCTGTGGAA 
CATAGAAGCT TAATCATGAA GAAACTGACT TATGCAAAGG AAACTGTAAG CAGCTCTGAA 
CTGTCTTCTC CAGTTCCTGT TGGTGATACT TCAACATTGG GAGACACTAC TCTCAGTGTT 
CCACATCCAG AGGTGGACGC CTATGAAGGT GCCTCAGAGA GCAGCTTGGA AAGGCCAGAG 
GAGAGTATTA GCAATGAAAT TGAGAATGTG ATAGAAGAAG CCACAAAACC AGCAGGTGAA 
CAGATTGCAG AATTCAGTAT CCACCTTTTG GGGAAGCAGT ACAGGGAAGA ACTACAGGAT 
TCCTCCAGCT TTCACCACCA GCACCTTGAA GAAGAATTTA TTTCAGAGGT TGAAAATGCA 
TTTACTGGGT TACCAGGCTA CAAGGAAATT CGTGTACTTG AATTTAGGTC CCCCAAGGAA 
AATGACAGTG GCGTAGATGT TTACTATGCA GTTACCTTCA ATGGTGAGGC CATCAGCAAT 
ACCACCTGGG ACCTCATTAG CCTTCACTCC AACAAGGTGG AAAACCATGG CCTTGTGGAA 
CTGGATGATA AACCCACTGT TGTTTATACA ATCAGTAACT TCAGAGATTA TATTGCTGAG 
ACATTGCAGC AGAATTTTTT GCTGGGGAAC TCTTCCTTGA ATCCAGATCC TGATTCCCTG 
CAGCTTATCA ATGTGAGAGG AGTTTTGCGT CACCAAACTG AAGATCTAGT TTGGAACACC 
CAAAGTTCAA GTCTTCAGGC AACGCCGTCA TCTATTCTGG ATAATACCTT TCAAGCTGCA 
TGGCCCTCAG CAGATGAATC CATCACCAGC AGTATTCCAC CACTTGATTT CAGCTCTGGT 
CCTCCCTCAG CCACTGGCAG GGAACTCTGG TCAGAAAGTC CTTTGGGTGA TTTAGTGTCT 
ACACACAAAT TAGCCTTTCC CTCGAAGATG GGCCTCAGCT CTTCCCCAGA GGTTTTAGAG 
GTTAGCAGCT TGACTCTTCA TTCTGTCACC CCGGCAGTGC TTCAGACTGG CTTGCCTGTG 
GCTTCTGAGG AAAGGACTTC TGGATCTCAC TTGGTAGAAG ATGGATTAGC CAATGTTGAA 
GAGTCAGAAG ATTTTCTTTC TATTGATTCA TTGCCTTCAA GTTCATTCAC TCAACCTGTG 
CCAAAAGAAA CAATACCATC CATGGAAGAC TCTGATGTGT CCTTAACATC TTCACCATAT 
CTGACCTCTT CTATACCTTT TGGCTTGGAC TCCTTGACCT CCAAAGTCAA AGACCAATTA 
AAAGTGAGCC CTTTCCTGCC AGATGCATCC ATGGAAAAAG AGTTAATATT TGACGGTGGT 
TTAGGTTCAG GGTCTGGGCA AAAGGTAGAT CTGATTACTT GGCCATGGAG TGAGACTTCA 
TCAGAGAAGA GCGCTGAACC ACTGTCCAAG CCGTGGCTTG AAGATGATGA TTCACTTTTG 
CCAGCTGAGA TTGAAGACAA GAAACTAGTT TTAGTTGACA AAATGGATTC CACAGACCAA 
ATTAGTAAGC ACTCAAAATA TGAACATGAT GACAGATCCA CACACTTTCC AGAGGAAGAG 
CCTCTTAGTG GGCCTGCTGT GCCCATCTTC GCAGATACTG CAGCTGAATC TGCGTCTCTA 
ACCCTCCCCA AGCACATATC AGAAGTACCT GGTGTTGATG ATTACTCAGT TACCAAAGCA 
CCTCTTATAC TGACATCTGT AGCAATCTCT GCCTCTACTG ATAAATCAGA TCAGGCAGAT 
GCCATCCTAA GGGAGGATAT GGAACAAATT ACTGAGTCAT CCAACTATGA ATGGTTTGAC 
AGTGAGGTTT CAATGGTAAA GCCAGATATG CAAACTTTGT GGACTATATT GCCAGAATCA 
GAGAGAGTTT GGACAAGAAC TTCTTCCCTA GAGAAATTGT CCAGAGACAT ATTGGCAAGT 
ACACCACAGA GTGCTGACAG GCTCTGGTTA TCTGTGACAC AGTCTACCAA ATTGCCTCCA 
ACCACAATCT CCACCCTGCT AGAGGATGAA GTAATTATGG GTGTACAGGA TATTTCGTTA 
GAACTGGACC GGATAGGCAC AGATTACTAT CAGCCTGAGC AAGTCCAAGA GCAAAATGGC 
AAGGTTGGTA GTTATGTGGA AATGTCAACA AGTGTTCACT CCACAGAGAT GGTTAGTGTG 
GCTTGGCCCA CAGAAGGAGG AGATGACTTG AGTTATACCC AGACTTCAGG AGCTTTGGTG 
GTTTTCTTCA GCCTCCGAGT GACTAACATG ATGTTTTCAG AAGATCTGTT TAATAAAAAC 
TCCTTGGAGT ATAAAGCCCT GGAGCAAAGA TTCTTAGAAT TGCTGGTTCC CTATCTCCAG 
TCAAATCTCA CGGGGTTCCA GAACTTAGAA ATCCTCAACT TCAGAAATGG CAGCATTGTG 
GTGAACAGTC GAATGAAGTT TGCCAATTCT GTCCCTCCTA ACGTCAACAA TGCGGTGTAC 
ATGATTCTGG AAGACTTTTG TACCACTGCC TACAATACCA TGAACTTGGC TATTGATAAA 
TACTCTCTTG ATGTGGAATC AGGTGATGAA GCCAACCCTT GCAAGTTTCA GGCCTGTAAT 
GAATTTTCAG AGTGTCTGGT CAACCCCTGG AGTGGAGAAG CAAAGTGCAG ATGCTTCCCT 
GGATACCTGA GTGTGGAAGA ACGGCCCTGT CAGAGTCTCT GTGACCTACA GCCTGACTTC 
TGCTTGAATG ATGGAAAGTG TGACATTATG CCTGGGCACG GGGCCATTTG TAGGTGCCGG 
GTGGGTGAGA ACTGGTGGTA CCGAGGCAAG CACTGTGAGG AATTTGTGTC TGAGCCCGTG 
ATCATAGGCA TCACTATTGC CTCCGTGGTT GGACTTCTTG TCATCTTTTC TGCTATCATC 
TACTTCTTCA TCAGGACTCT CCAAGCACAC CATGACAGGA GTGAAAGAGA GAGTCCCTTC 
AGTGGCTCCA GCAGGCAGCC TGACAGCCTC TCATCTATTG AGAATGCTGT GAAGTACAAC 
CCCGTGTATG AAAGTCACAG GGCTGGATGT GAGAAGTATG AGGGACCCTA TCCTCAGCAT 
CCCTTCTACA GCTCTGCTAG CGGAGACGTG ATTGGTGGGC TGAGCAGAGA AGAAATCAGA 
CAGATGTATG AGAGCAGTGA GCTTTCCAGA GAGGAAATTC AAGAGAGAAT GAGAGTTTTG 
GAACTGTATG CCAATGATCC TGAGTTTGCA GCTTTTGTGA GAGAGCAACA AGTGGAAGAG 
GTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IMPG2 ( NM_016247.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_057331.2 Homo sapiens interphotoreceptor matrix proteoglycan 2 (IMPG2), mRNA.

Price & Availability↑

CloneID	OHu20511
Clone ID Related Accession (Same CDS sequence)	NM_016247.3 , NM_016247.4
Accession Version	NM_016247.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3726bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	interphotoreceptor matrix proteoglycan 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX953286.1, AB593127.1, AC093008.10 and BM671068.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_016247.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AB593127.1, AF173155.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000193391.8/ ENSP00000193391.6 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGATTATGT TTCCTCTTTT TGGGAAGATT TCTCTGGGTA TTTTGATATT TGTCCTGATA 
GAAGGAGACT TTCCATCATT AACAGCACAA ACCTACTTAT CTATAGAGGA GATCCAAGAA 
CCCAAGAGTG CAGTTTCTTT TCTCCTGCCT GAAGAATCAA CAGACCTTTC TCTAGCTACC 
AAAAAGAAAC AGCCTCTGGA CCGCAGAGAA ACTGAAAGAC AGTGGTTAAT CAGAAGGCGG 
AGATCTATTC TGTTTCCTAA TGGAGTGAAA ATCTGCCCAG ATGAAAGTGT TGCAGAGGCT 
GTGGCAAATC ATGTGAAGTA TTTTAAAGTC CGAGTGTGTC AGGAAGCTGT CTGGGAAGCC 
TTCAGGACTT TTTGGGATCG ACTTCCTGGG CGTGAGGAAT ATCATTACTG GATGAATTTG 
TGTGAGGATG GAGTCACAAG TATATTTGAA ATGGGCACAA ATTTTAGTGA ATCTGTGGAA 
CATAGAAGCT TAATCATGAA GAAACTGACT TATGCAAAGG AAACTGTAAG CAGCTCTGAA 
CTGTCTTCTC CAGTTCCTGT TGGTGATACT TCAACATTGG GAGACACTAC TCTCAGTGTT 
CCACATCCAG AGGTGGACGC CTATGAAGGT GCCTCAGAGA GCAGCTTGGA AAGGCCAGAG 
GAGAGTATTA GCAATGAAAT TGAGAATGTG ATAGAAGAAG CCACAAAACC AGCAGGTGAA 
CAGATTGCAG AATTCAGTAT CCACCTTTTG GGGAAGCAGT ACAGGGAAGA ACTACAGGAT 
TCCTCCAGCT TTCACCACCA GCACCTTGAA GAAGAATTTA TTTCAGAGGT TGAAAATGCA 
TTTACTGGGT TACCAGGCTA CAAGGAAATT CGTGTACTTG AATTTAGGTC CCCCAAGGAA 
AATGACAGTG GCGTAGATGT TTACTATGCA GTTACCTTCA ATGGTGAGGC CATCAGCAAT 
ACCACCTGGG ACCTCATTAG CCTTCACTCC AACAAGGTGG AAAACCATGG CCTTGTGGAA 
CTGGATGATA AACCCACTGT TGTTTATACA ATCAGTAACT TCAGAGATTA TATTGCTGAG 
ACATTGCAGC AGAATTTTTT GCTGGGGAAC TCTTCCTTGA ATCCAGATCC TGATTCCCTG 
CAGCTTATCA ATGTGAGAGG AGTTTTGCGT CACCAAACTG AAGATCTAGT TTGGAACACC 
CAAAGTTCAA GTCTTCAGGC AACGCCGTCA TCTATTCTGG ATAATACCTT TCAAGCTGCA 
TGGCCCTCAG CAGATGAATC CATCACCAGC AGTATTCCAC CACTTGATTT CAGCTCTGGT 
CCTCCCTCAG CCACTGGCAG GGAACTCTGG TCAGAAAGTC CTTTGGGTGA TTTAGTGTCT 
ACACACAAAT TAGCCTTTCC CTCGAAGATG GGCCTCAGCT CTTCCCCAGA GGTTTTAGAG 
GTTAGCAGCT TGACTCTTCA TTCTGTCACC CCGGCAGTGC TTCAGACTGG CTTGCCTGTG 
GCTTCTGAGG AAAGGACTTC TGGATCTCAC TTGGTAGAAG ATGGATTAGC CAATGTTGAA 
GAGTCAGAAG ATTTTCTTTC TATTGATTCA TTGCCTTCAA GTTCATTCAC TCAACCTGTG 
CCAAAAGAAA CAATACCATC CATGGAAGAC TCTGATGTGT CCTTAACATC TTCACCATAT 
CTGACCTCTT CTATACCTTT TGGCTTGGAC TCCTTGACCT CCAAAGTCAA AGACCAATTA 
AAAGTGAGCC CTTTCCTGCC AGATGCATCC ATGGAAAAAG AGTTAATATT TGACGGTGGT 
TTAGGTTCAG GGTCTGGGCA AAAGGTAGAT CTGATTACTT GGCCATGGAG TGAGACTTCA 
TCAGAGAAGA GCGCTGAACC ACTGTCCAAG CCGTGGCTTG AAGATGATGA TTCACTTTTG 
CCAGCTGAGA TTGAAGACAA GAAACTAGTT TTAGTTGACA AAATGGATTC CACAGACCAA 
ATTAGTAAGC ACTCAAAATA TGAACATGAT GACAGATCCA CACACTTTCC AGAGGAAGAG 
CCTCTTAGTG GGCCTGCTGT GCCCATCTTC GCAGATACTG CAGCTGAATC TGCGTCTCTA 
ACCCTCCCCA AGCACATATC AGAAGTACCT GGTGTTGATG ATTACTCAGT TACCAAAGCA 
CCTCTTATAC TGACATCTGT AGCAATCTCT GCCTCTACTG ATAAATCAGA TCAGGCAGAT 
GCCATCCTAA GGGAGGATAT GGAACAAATT ACTGAGTCAT CCAACTATGA ATGGTTTGAC 
AGTGAGGTTT CAATGGTAAA GCCAGATATG CAAACTTTGT GGACTATATT GCCAGAATCA 
GAGAGAGTTT GGACAAGAAC TTCTTCCCTA GAGAAATTGT CCAGAGACAT ATTGGCAAGT 
ACACCACAGA GTGCTGACAG GCTCTGGTTA TCTGTGACAC AGTCTACCAA ATTGCCTCCA 
ACCACAATCT CCACCCTGCT AGAGGATGAA GTAATTATGG GTGTACAGGA TATTTCGTTA 
GAACTGGACC GGATAGGCAC AGATTACTAT CAGCCTGAGC AAGTCCAAGA GCAAAATGGC 
AAGGTTGGTA GTTATGTGGA AATGTCAACA AGTGTTCACT CCACAGAGAT GGTTAGTGTG 
GCTTGGCCCA CAGAAGGAGG AGATGACTTG AGTTATACCC AGACTTCAGG AGCTTTGGTG 
GTTTTCTTCA GCCTCCGAGT GACTAACATG ATGTTTTCAG AAGATCTGTT TAATAAAAAC 
TCCTTGGAGT ATAAAGCCCT GGAGCAAAGA TTCTTAGAAT TGCTGGTTCC CTATCTCCAG 
TCAAATCTCA CGGGGTTCCA GAACTTAGAA ATCCTCAACT TCAGAAATGG CAGCATTGTG 
GTGAACAGTC GAATGAAGTT TGCCAATTCT GTCCCTCCTA ACGTCAACAA TGCGGTGTAC 
ATGATTCTGG AAGACTTTTG TACCACTGCC TACAATACCA TGAACTTGGC TATTGATAAA 
TACTCTCTTG ATGTGGAATC AGGTGATGAA GCCAACCCTT GCAAGTTTCA GGCCTGTAAT 
GAATTTTCAG AGTGTCTGGT CAACCCCTGG AGTGGAGAAG CAAAGTGCAG ATGCTTCCCT 
GGATACCTGA GTGTGGAAGA ACGGCCCTGT CAGAGTCTCT GTGACCTACA GCCTGACTTC 
TGCTTGAATG ATGGAAAGTG TGACATTATG CCTGGGCACG GGGCCATTTG TAGGTGCCGG 
GTGGGTGAGA ACTGGTGGTA CCGAGGCAAG CACTGTGAGG AATTTGTGTC TGAGCCCGTG 
ATCATAGGCA TCACTATTGC CTCCGTGGTT GGACTTCTTG TCATCTTTTC TGCTATCATC 
TACTTCTTCA TCAGGACTCT CCAAGCACAC CATGACAGGA GTGAAAGAGA GAGTCCCTTC 
AGTGGCTCCA GCAGGCAGCC TGACAGCCTC TCATCTATTG AGAATGCTGT GAAGTACAAC 
CCCGTGTATG AAAGTCACAG GGCTGGATGT GAGAAGTATG AGGGACCCTA TCCTCAGCAT 
CCCTTCTACA GCTCTGCTAG CGGAGACGTG ATTGGTGGGC TGAGCAGAGA AGAAATCAGA 
CAGATGTATG AGAGCAGTGA GCTTTCCAGA GAGGAAATTC AAGAGAGAAT GAGAGTTTTG 
GAACTGTATG CCAATGATCC TGAGTTTGCA GCTTTTGTGA GAGAGCAACA AGTGGAAGAG 
GTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057331.2
CDS	204..3929
Translation	MIMFPLFGKISLGILIFVLIEGDFPSLTAQTYLSIEEIQEPKSAVSFLLPEESTDLSLATKKKQPLDRRETERQWLIRRRRSILFPNGVKICPDESVAEAVANHVKYFKVRVCQEAVWEAFRTFWDRLPGREEYHYWMNLCEDGVTSIFEMGTNFSESVEHRSLIMKKLTYAKETVSSSELSSPVPVGDTSTLGDTTLSVPHPEVDAYEGASESSLERPEESISNEIENVIEEATKPAGEQIAEFSIHLLGKQYREELQDSSSFHHQHLEEEFISEVENAFTGLPGYKEIRVLEFRSPKENDSGVDVYYAVTFNGEAISNTTWDLISLHSNKVENHGLVELDDKPTVVYTISNFRDYIAETLQQNFLLGNSSLNPDPDSLQLINVRGVLRHQTEDLVWNTQSSSLQATPSSILDNTFQAAWPSADESITSSIPPLDFSSGPPSATGRELWSESPLGDLVSTHKLAFPSKMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPVASEERTSGSHLVEDGLANVEESEDFLSIDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIPFGLDSLTSKVKDQLKVSPFLPDASMEKELIFDGGLGSGSGQKVDLITWPWSETSSEKSAEPLSKPWLEDDDSLLPAEIEDKKLVLVDKMDSTDQISKHSKYEHDDRSTHFPEEEPLSGPAVPIFADTAAESASLTLPKHISEVPGVDDYSVTKAPLILTSVAISASTDKSDQADAILREDMEQITESSNYEWFDSEVSMVKPDMQTLWTILPESERVWTRTSSLEKLSRDILASTPQSADRLWLSVTQSTKLPPTTISTLLEDEVIMGVQDISLELDRIGTDYYQPEQVQEQNGKVGSYVEMSTSVHSTEMVSVAWPTEGGDDLSYTQTSGALVVFFSLRVTNMMFSEDLFNKNSLEYKALEQRFLELLVPYLQSNLTGFQNLEILNFRNGSIVVNSRMKFANSVPPNVNNAVYMILEDFCTTAYNTMNLAIDKYSLDVESGDEANPCKFQACNEFSECLVNPWSGEAKCRCFPGYLSVEERPCQSLCDLQPDFCLNDGKCDIMPGHGAICRCRVGENWWYRGKHCEEFVSEPVIIGITIASVVGLLVIFSAIIYFFIRTLQAHHDRSERESPFSGSSRQPDSLSSIENAVKYNPVYESHRAGCEKYEGPYPQHPFYSSASGDVIGGLSREEIRQMYESSELSREEIQERMRVLELYANDPEFAAFVREQQVEEV

Target ORF information:

RefSeq Version	NM_016247.4
Organism	Homo sapiens(human)
Definition	Homo sapiens interphotoreceptor matrix proteoglycan 2 (IMPG2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016247.4

ORF Insert Sequence:

ATGATTATGT TTCCTCTTTT TGGGAAGATT TCTCTGGGTA TTTTGATATT TGTCCTGATA 
GAAGGAGACT TTCCATCATT AACAGCACAA ACCTACTTAT CTATAGAGGA GATCCAAGAA 
CCCAAGAGTG CAGTTTCTTT TCTCCTGCCT GAAGAATCAA CAGACCTTTC TCTAGCTACC 
AAAAAGAAAC AGCCTCTGGA CCGCAGAGAA ACTGAAAGAC AGTGGTTAAT CAGAAGGCGG 
AGATCTATTC TGTTTCCTAA TGGAGTGAAA ATCTGCCCAG ATGAAAGTGT TGCAGAGGCT 
GTGGCAAATC ATGTGAAGTA TTTTAAAGTC CGAGTGTGTC AGGAAGCTGT CTGGGAAGCC 
TTCAGGACTT TTTGGGATCG ACTTCCTGGG CGTGAGGAAT ATCATTACTG GATGAATTTG 
TGTGAGGATG GAGTCACAAG TATATTTGAA ATGGGCACAA ATTTTAGTGA ATCTGTGGAA 
CATAGAAGCT TAATCATGAA GAAACTGACT TATGCAAAGG AAACTGTAAG CAGCTCTGAA 
CTGTCTTCTC CAGTTCCTGT TGGTGATACT TCAACATTGG GAGACACTAC TCTCAGTGTT 
CCACATCCAG AGGTGGACGC CTATGAAGGT GCCTCAGAGA GCAGCTTGGA AAGGCCAGAG 
GAGAGTATTA GCAATGAAAT TGAGAATGTG ATAGAAGAAG CCACAAAACC AGCAGGTGAA 
CAGATTGCAG AATTCAGTAT CCACCTTTTG GGGAAGCAGT ACAGGGAAGA ACTACAGGAT 
TCCTCCAGCT TTCACCACCA GCACCTTGAA GAAGAATTTA TTTCAGAGGT TGAAAATGCA 
TTTACTGGGT TACCAGGCTA CAAGGAAATT CGTGTACTTG AATTTAGGTC CCCCAAGGAA 
AATGACAGTG GCGTAGATGT TTACTATGCA GTTACCTTCA ATGGTGAGGC CATCAGCAAT 
ACCACCTGGG ACCTCATTAG CCTTCACTCC AACAAGGTGG AAAACCATGG CCTTGTGGAA 
CTGGATGATA AACCCACTGT TGTTTATACA ATCAGTAACT TCAGAGATTA TATTGCTGAG 
ACATTGCAGC AGAATTTTTT GCTGGGGAAC TCTTCCTTGA ATCCAGATCC TGATTCCCTG 
CAGCTTATCA ATGTGAGAGG AGTTTTGCGT CACCAAACTG AAGATCTAGT TTGGAACACC 
CAAAGTTCAA GTCTTCAGGC AACGCCGTCA TCTATTCTGG ATAATACCTT TCAAGCTGCA 
TGGCCCTCAG CAGATGAATC CATCACCAGC AGTATTCCAC CACTTGATTT CAGCTCTGGT 
CCTCCCTCAG CCACTGGCAG GGAACTCTGG TCAGAAAGTC CTTTGGGTGA TTTAGTGTCT 
ACACACAAAT TAGCCTTTCC CTCGAAGATG GGCCTCAGCT CTTCCCCAGA GGTTTTAGAG 
GTTAGCAGCT TGACTCTTCA TTCTGTCACC CCGGCAGTGC TTCAGACTGG CTTGCCTGTG 
GCTTCTGAGG AAAGGACTTC TGGATCTCAC TTGGTAGAAG ATGGATTAGC CAATGTTGAA 
GAGTCAGAAG ATTTTCTTTC TATTGATTCA TTGCCTTCAA GTTCATTCAC TCAACCTGTG 
CCAAAAGAAA CAATACCATC CATGGAAGAC TCTGATGTGT CCTTAACATC TTCACCATAT 
CTGACCTCTT CTATACCTTT TGGCTTGGAC TCCTTGACCT CCAAAGTCAA AGACCAATTA 
AAAGTGAGCC CTTTCCTGCC AGATGCATCC ATGGAAAAAG AGTTAATATT TGACGGTGGT 
TTAGGTTCAG GGTCTGGGCA AAAGGTAGAT CTGATTACTT GGCCATGGAG TGAGACTTCA 
TCAGAGAAGA GCGCTGAACC ACTGTCCAAG CCGTGGCTTG AAGATGATGA TTCACTTTTG 
CCAGCTGAGA TTGAAGACAA GAAACTAGTT TTAGTTGACA AAATGGATTC CACAGACCAA 
ATTAGTAAGC ACTCAAAATA TGAACATGAT GACAGATCCA CACACTTTCC AGAGGAAGAG 
CCTCTTAGTG GGCCTGCTGT GCCCATCTTC GCAGATACTG CAGCTGAATC TGCGTCTCTA 
ACCCTCCCCA AGCACATATC AGAAGTACCT GGTGTTGATG ATTACTCAGT TACCAAAGCA 
CCTCTTATAC TGACATCTGT AGCAATCTCT GCCTCTACTG ATAAATCAGA TCAGGCAGAT 
GCCATCCTAA GGGAGGATAT GGAACAAATT ACTGAGTCAT CCAACTATGA ATGGTTTGAC 
AGTGAGGTTT CAATGGTAAA GCCAGATATG CAAACTTTGT GGACTATATT GCCAGAATCA 
GAGAGAGTTT GGACAAGAAC TTCTTCCCTA GAGAAATTGT CCAGAGACAT ATTGGCAAGT 
ACACCACAGA GTGCTGACAG GCTCTGGTTA TCTGTGACAC AGTCTACCAA ATTGCCTCCA 
ACCACAATCT CCACCCTGCT AGAGGATGAA GTAATTATGG GTGTACAGGA TATTTCGTTA 
GAACTGGACC GGATAGGCAC AGATTACTAT CAGCCTGAGC AAGTCCAAGA GCAAAATGGC 
AAGGTTGGTA GTTATGTGGA AATGTCAACA AGTGTTCACT CCACAGAGAT GGTTAGTGTG 
GCTTGGCCCA CAGAAGGAGG AGATGACTTG AGTTATACCC AGACTTCAGG AGCTTTGGTG 
GTTTTCTTCA GCCTCCGAGT GACTAACATG ATGTTTTCAG AAGATCTGTT TAATAAAAAC 
TCCTTGGAGT ATAAAGCCCT GGAGCAAAGA TTCTTAGAAT TGCTGGTTCC CTATCTCCAG 
TCAAATCTCA CGGGGTTCCA GAACTTAGAA ATCCTCAACT TCAGAAATGG CAGCATTGTG 
GTGAACAGTC GAATGAAGTT TGCCAATTCT GTCCCTCCTA ACGTCAACAA TGCGGTGTAC 
ATGATTCTGG AAGACTTTTG TACCACTGCC TACAATACCA TGAACTTGGC TATTGATAAA 
TACTCTCTTG ATGTGGAATC AGGTGATGAA GCCAACCCTT GCAAGTTTCA GGCCTGTAAT 
GAATTTTCAG AGTGTCTGGT CAACCCCTGG AGTGGAGAAG CAAAGTGCAG ATGCTTCCCT 
GGATACCTGA GTGTGGAAGA ACGGCCCTGT CAGAGTCTCT GTGACCTACA GCCTGACTTC 
TGCTTGAATG ATGGAAAGTG TGACATTATG CCTGGGCACG GGGCCATTTG TAGGTGCCGG 
GTGGGTGAGA ACTGGTGGTA CCGAGGCAAG CACTGTGAGG AATTTGTGTC TGAGCCCGTG 
ATCATAGGCA TCACTATTGC CTCCGTGGTT GGACTTCTTG TCATCTTTTC TGCTATCATC 
TACTTCTTCA TCAGGACTCT CCAAGCACAC CATGACAGGA GTGAAAGAGA GAGTCCCTTC 
AGTGGCTCCA GCAGGCAGCC TGACAGCCTC TCATCTATTG AGAATGCTGT GAAGTACAAC 
CCCGTGTATG AAAGTCACAG GGCTGGATGT GAGAAGTATG AGGGACCCTA TCCTCAGCAT 
CCCTTCTACA GCTCTGCTAG CGGAGACGTG ATTGGTGGGC TGAGCAGAGA AGAAATCAGA 
CAGATGTATG AGAGCAGTGA GCTTTCCAGA GAGGAAATTC AAGAGAGAAT GAGAGTTTTG 
GAACTGTATG CCAATGATCC TGAGTTTGCA GCTTTTGTGA GAGAGCAACA AGTGGAAGAG 
GTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Frequency and clinical pattern of vitelliform macular dystrophy caused by mutations of interphotoreceptor matrix IMPG1 and IMPG2 genes.
Ophthalmology121(12)2406-14(2014 Dec)
Meunier I,Manes G,Bocquet B,Marquette V,Baudoin C,Puech B,Defoort-Dhellemmes S,Audo I,Verdet R,Arndt C,Zanlonghi X,Le Meur G,Dhaenens CM,Hamel CP

IMPG2-associated retinitis pigmentosa displays relatively early macular involvement.
Investigative ophthalmology & visual science55(6)3939-53(2014 May)
van Huet RA,Collin RW,Siemiatkowska AM,Klaver CC,Hoyng CB,Simonelli F,Khan MI,Qamar R,Banin E,Cremers FP,Theelen T,den Hollander AI,van den Born LI,Klevering BJ

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.
Proceedings of the National Academy of Sciences of the United States of America110(8)E643-52(2013 Feb)
Ghai R,Bugarcic A,Liu H,Norwood SJ,Skeldal S,Coulson EJ,Li SS,Teasdale RD,Collins BM

Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method.
Investigative ophthalmology & visual science52(9)6662-70(2011 Aug)
Oshikawa M,Tsutsui C,Ikegami T,Fuchida Y,Matsubara M,Toyama S,Usami R,Ohtoko K,Kato S

Mutations in IMPG2, encoding interphotoreceptor matrix proteoglycan 2, cause autosomal-recessive retinitis pigmentosa.
American journal of human genetics87(2)199-208(2010 Aug)
Bandah-Rozenfeld D,Collin RW,Banin E,van den Born LI,Coene KL,Siemiatkowska AM,Zelinger L,Khan MI,Lefeber DJ,Erdinest I,Testa F,Simonelli F,Voesenek K,Blokland EA,Strom TM,Klaver CC,Qamar R,Banfi S,Cremers FP,Sharon D,den Hollander AI

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IMPG2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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