NOTCH4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	NOTCH4
Entrez Gene ID	4855
Full Name	notch 4
Synonyms	INT3
General protein information	Preferred Names notch 4 Names neurogenic locus notch homolog protein 4 Notch homolog 4
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6p21.32
Summary	This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor may play a role in vascular, renal and hepatic development. Mutations in this gene may be associated with schizophrenia. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016].
Disorder MIM:	164951

mRNA and Protein(s)

mRNA	Protein	Name
NM_004557.3	NP_004548.3	neurogenic locus notch homolog protein 4 preproprotein
NM_004557.4	NP_004548.3	neurogenic locus notch homolog protein 4 preproprotein

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	NOTCH4	XP_005627807.1
Homo sapiens (human)	NOTCH4	NP_004548.3
Pan troglodytes (chimpanzee)	NOTCH4	XP_518380.3
Bos taurus (cattle)	NOTCH4	NP_001193877.1
Mus musculus (house mouse)	Notch4	NP_035059.2
Rattus norvegicus (Norway rat)	Notch4	NP_001002827.1

Gene Ontology
Bibliography

Related articles in PubMed

Human
Li Y, Jin C, Bai H, Gao Y, Sun S, Chen L, Qin L, Liu PP, Cheng L, Wang QF
Blood131(2)191-201(2018 Jan)

The
Fukusumi T, Guo TW, Sakai A, Ando M, Ren S, Haft S, Liu C, Amornphimoltham P, Gutkind JS, Califano JA
Clinical cancer research : an official journal of the American Association for Cancer Research(2017 Nov)

Downregulation of Notch4 - a prognostic marker in distinguishing oral verrucous carcinoma from oral squamous cell carcinoma.
Harishankar MK, Mohan AM, Krishnan AV, Devi A
Brazilian journal of otorhinolaryngology(2017 Oct)

Prognostic roles of mRNA expression of notch receptors in non-small cell lung cancer.
Xiong J, Zhang X, Chen X, Wei Y, Lu DG, Han YW, Xu J, Yu D
Oncotarget8(8)13157-13165(2017 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Sirt6 inhibits Notch1 and Notch4 transcription by deacetylating histone H3K9.
Title: Sirt6 deficiency exacerbates podocyte injury and proteinuria through targeting Notch signaling.

Data indicate that mRNA high expression level of Notch1 was associated with better overall survival (OS) for all NSCLC, hazard ratio (HR), better OS in adenocarcinoma (Ade), HR, as well as in squamous cell carcinoma (SCC), HR, and mRNA high expression levels of Notch2 and Notch3 were associated with worsen OS for all NSCLC, and mRNA high expression level of Notch4 was not found to be associated with to OS for all NSCLC.
Title: Prognostic roles of mRNA expression of notch receptors in non-small cell lung cancer.

Very rare missense variant in the regulatory NODP domain of NOTCH4 located at the 6p21 locus was identified in a single family.This family suggests a novel mechanism of systemic sclerosis pathogenesis in which a rare and penetrant coding variation can substantially elevate disease risk in contrast to the more modest non-coding variation typically found at this locus.
Title: Association of a rare NOTCH4 coding variant with systemic sclerosis: a family-based whole exome sequencing study.

findings indicate that Notch4+ melanoma cancer stem-like cells trigger epithelial-mesenchymal transition and promote the metastasis of melanoma cells
Title: Notch4+ cancer stem-like cells promote the metastatic and invasive ability of melanoma.

Reduced NOTCH3/NICD3 and NOTCH4/NICD4 in miR-96- and miR-183-expressing nasopharyngeal carcinoma (NPC) cells suggest the involvement of the NOTCH signaling pathway in their tumor suppressive function.
Title: MicroRNA-183 suppresses cancer stem-like cell properties in EBV-associated nasopharyngeal carcinoma.

The following NOTCH4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NOTCH4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu27711	NM_004557.4 Latest version!	Homo sapiens notch receptor 4 (NOTCH4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	22-24	$1091.30 $1559.00
View Old Accession Versions >>
OHu27711	NM_004557.3	Homo sapiens notch 4 (NOTCH4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	22-24	$1091.30 $1559.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

NOTCH4 ( NM_004557.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_004548.3 Homo sapiens notch 4 (NOTCH4), mRNA.

Price & Availability↑

CloneID	OHu27711
Clone ID Related Accession (Same CDS sequence)	NM_004557.3 , NM_004557.4
Accession Version	NM_004557.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 6012bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-19
Organism	Homo sapiens(human)
Product	neurogenic locus notch homolog protein 4 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL705928.1, U95299.1, D63395.1 and BQ023880.1. This sequence is a reference standard in the RefSeqGene project. On Nov 15, 2004 this sequence version replaced NM_004557.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC140782.1, U95299.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAGCCCC CTTCACTGCT GCTGCTGCTG CTGCTGCTGC TGCTGCTATG TGTCTCAGTG 
GTCAGACCCA GAGGGCTGCT GTGTGGGAGT TTCCCAGAAC CCTGTGCCAA TGGAGGCACC 
TGCCTGAGCC TGTCTCTGGG ACAAGGGACC TGCCAGTGTG CCCCTGGCTT CCTGGGTGAG 
ACGTGCCAGT TTCCTGACCC CTGCCAGAAC GCCCAGCTCT GCCAAAATGG AGGCAGCTGC 
CAAGCCCTGC TTCCCGCTCC CCTAGGGCTC CCCAGCTCTC CCTCTCCATT GACACCCAGC 
TTCTTGTGCA CTTGCCTCCC TGGCTTCACT GGTGAGAGAT GCCAGGCCAA GCTTGAAGAC 
CCTTGTCCTC CCTCCTTCTG TTCCAAAAGG GGCCGCTGCC ACATCCAGGC CTCGGGCCGC 
CCACAGTGCT CCTGCATGCC TGGATGGACA GGTGAGCAGT GCCAGCTTCG GGACTTCTGT 
TCAGCCAACC CATGTGTTAA TGGAGGGGTG TGTCTGGCCA CATACCCCCA GATCCAGTGC 
CACTGCCCAC CGGGCTTCGA GGGCCATGCC TGTGAACGTG ATGTCAACGA GTGCTTCCAG 
GACCCAGGAC CCTGCCCCAA AGGCACCTCC TGCCATAACA CCCTGGGCTC CTTCCAGTGC 
CTCTGCCCTG TGGGGCAGGA GGGTCCACGT TGTGAGCTGC GGGCAGGACC CTGCCCTCCT 
AGGGGCTGTT CGAATGGGGG CACCTGCCAG CTGATGCCAG AGAAAGACTC CACCTTTCAC 
CTCTGCCTCT GTCCCCCAGG TTTCATAGGC CCAGACTGTG AGGTGAATCC AGACAACTGT 
GTCAGCCACC AGTGTCAGAA TGGGGGCACT TGCCAGGATG GGCTGGACAC CTACACCTGC 
CTCTGCCCAG AAACCTGGAC AGGCTGGGAC TGCTCCGAAG ATGTGGATGA GTGTGAGACC 
CAGGGTCCCC CTCACTGCAG AAACGGGGGC ACCTGCCAGA ACTCTGCTGG TAGCTTTCAC 
TGCGTGTGTG TGAGTGGCTG GGGCGGCACA AGCTGTGAGG AGAACCTGGA TGACTGTATT 
GCTGCCACCT GTGCCCCGGG ATCCACCTGC ATTGACCGGG TGGGCTCTTT CTCCTGCCTC 
TGCCCACCTG GACGCACAGG ACTCCTGTGC CACTTGGAAG ACATGTGTCT GAGCCAGCCG 
TGCCATGGGG ATGCCCAATG CAGCACCAAC CCCCTCACAG GCTCCACACT CTGCCTGTGT 
CAGCCTGGCT ATTCGGGGCC CACCTGCCAC CAGGACCTGG ACGAGTGTCT GATGGCCCAG 
CAAGGCCCAA GTCCCTGTGA ACATGGCGGT TCCTGCCTCA ACACTCCTGG CTCCTTCAAC 
TGCCTCTGTC CACCTGGCTA CACAGGCTCC CGTTGTGAGG CTGATCACAA TGAGTGCCTC 
TCCCAGCCCT GCCACCCAGG AAGCACCTGT CTGGACCTAC TTGCCACCTT CCACTGCCTC 
TGCCCGCCAG GCTTAGAAGG GCAGCTCTGT GAGGTGGAGA CCAACGAGTG TGCCTCAGCT 
CCCTGCCTGA ACCACGCGGA TTGCCATGAC CTGCTCAACG GCTTCCAGTG CATCTGCCTG 
CCTGGATTCT CCGGCACCCG ATGTGAGGAG GATATCGATG AGTGCAGAAG CTCTCCCTGT 
GCCAATGGTG GGCAGTGCCA GGACCAGCCT GGAGCCTTCC ACTGCAAGTG TCTCCCAGGC 
TTTGAAGGGC CACGCTGTCA AACAGAGGTG GATGAGTGCC TGAGTGACCC ATGTCCCGTT 
GGAGCCAGCT GCCTTGATCT TCCAGGAGCC TTCTTTTGCC TCTGCCCCTC TGGTTTCACA 
GGCCAGCTCT GTGAGGTTCC CCTGTGTGCT CCCAACCTGT GCCAGCCCAA GCAGATATGT 
AAGGACCAGA AAGACAAGGC CAACTGCCTC TGTCCTGATG GAAGCCCTGG CTGTGCCCCA 
CCTGAGGACA ACTGCACCTG CCACCACGGG CACTGCCAGA GATCCTCATG TGTGTGTGAC 
GTGGGTTGGA CGGGGCCAGA GTGTGAGGCA GAGCTAGGGG GCTGCATCTC TGCACCCTGT 
GCCCATGGGG GGACCTGCTA CCCCCAGCCC TCTGGCTACA ACTGCACCTG CCCTACAGGC 
TACACAGGAC CCACCTGTAG TGAGGAGATG ACAGCTTGTC ACTCAGGGCC ATGTCTCAAT 
GGCGGCTCCT GCAACCCTAG CCCTGGAGGC TACTACTGCA CCTGCCCTCC AAGCCACACA 
GGGCCCCAGT GCCAAACCAG CACTGACTAC TGTGTGTCTG CCCCGTGCTT CAATGGGGGT 
ACCTGTGTGA ACAGGCCTGG CACCTTCTCC TGCCTCTGTG CCATGGGCTT CCAGGGCCCG 
CGCTGTGAGG GAAAGCTCCG CCCCAGCTGT GCAGACAGCC CCTGTAGGAA TAGGGCAACC 
TGCCAGGACA GCCCTCAGGG TCCCCGCTGC CTCTGCCCCA CTGGCTACAC CGGAGGCAGC 
TGCCAGACTC TGATGGACTT ATGTGCCCAG AAGCCCTGCC CACGCAATTC CCACTGCCTC 
CAGACTGGGC CCTCCTTCCA CTGCTTGTGC CTCCAGGGAT GGACCGGGCC TCTCTGCAAC 
CTTCCACTGT CCTCCTGCCA GAAGGCTGCA CTGAGCCAAG GCATAGACGT CTCTTCCCTT 
TGCCACAATG GAGGCCTCTG TGTCGACAGC GGCCCCTCCT ATTTCTGCCA CTGCCCCCCT 
GGATTCCAAG GCAGCCTGTG CCAGGATCAC GTGAACCCAT GTGAGTCCAG GCCTTGCCAG 
AACGGGGCCA CCTGCATGGC CCAGCCCAGT GGGTATCTCT GCCAGTGTGC CCCAGGCTAC 
GATGGACAGA ACTGCTCAAA GGAACTCGAT GCTTGTCAGT CCCAACCCTG TCACAACCAT 
GGAACCTGTA CTCCCAAACC TGGAGGATTC CACTGTGCCT GCCCTCCAGG CTTTGTGGGG 
CTACGCTGTG AGGGAGACGT GGACGAGTGT CTGGACCAGC CCTGCCACCC CACAGGCACT 
GCAGCCTGCC ACTCTCTGGC CAATGCCTTC TACTGCCAGT GTCTGCCTGG ACACACAGGC 
CAGTGGTGTG AGGTGGAGAT AGACCCCTGC CACAGCCAAC CCTGCTTTCA TGGAGGGACC 
TGTGAGGCCA CAGCAGGATC ACCCCTGGGT TTCATCTGCC ACTGCCCCAA GGGTTTTGAA 
GGCCCCACCT GCAGCCACAG GGCCCCTTCC TGCGGCTTCC ATCACTGCCA CCACGGAGGC 
CTGTGTCTGC CCTCCCCTAA GCCAGGCTTC CCACCACGCT GTGCCTGCCT CAGTGGCTAT 
GGGGGTCCTG ACTGCCTGAC CCCACCAGCT CCTAAAGGCT GTGGCCCTCC CTCCCCATGC 
CTATACAATG GCAGCTGCTC AGAGACCACG GGCTTGGGGG GCCCAGGCTT TCGATGCTCC 
TGCCCTCACA GCTCTCCAGG GCCCCGGTGT CAGAAACCCG GAGCCAAGGG GTGTGAGGGC 
AGAAGTGGAG ATGGGGCCTG CGATGCTGGC TGCAGTGGCC CGGGAGGAAA CTGGGATGGA 
GGGGACTGCT CTCTGGGAGT CCCAGACCCC TGGAAGGGCT GCCCCTCCCA CTCTCGGTGC 
TGGCTTCTCT TCCGGGACGG GCAGTGCCAC CCACAGTGTG ACTCTGAAGA GTGTCTGTTT 
GATGGCTACG ACTGTGAGAC CCCTCCAGCC TGCACTCCAG CCTATGACCA GTACTGCCAT 
GATCACTTCC ACAACGGGCA CTGTGAGAAA GGCTGCAACA CTGCAGAGTG TGGCTGGGAT 
GGAGGTGACT GCAGGCCTGA AGATGGGGAC CCAGAGTGGG GGCCCTCCCT GGCCCTGCTG 
GTGGTACTGA GCCCCCCAGC CCTAGACCAG CAGCTGTTTG CCCTGGCCCG GGTGCTGTCC 
CTGACTCTGA GGGTAGGACT CTGGGTAAGG AAGGATCGTG ATGGCAGGGA CATGGTGTAC 
CCCTATCCTG GGGCCCGGGC TGAAGAAAAG CTAGGAGGAA CTCGGGACCC CACCTATCAG 
GAGAGAGCAG CCCCTCAAAC GCAGCCCCTG GGCAAGGAGA CCGACTCCCT CAGTGCTGGG 
TTTGTGGTGG TCATGGGTGT GGATTTGTCC CGCTGTGGCC CTGACCACCC GGCATCCCGC 
TGTCCCTGGG ACCCTGGGCT TCTACTCCGC TTCCTTGCTG CGATGGCTGC AGTGGGAGCC 
CTGGAGCCCC TGCTGCCTGG ACCACTGCTG GCTGTCCACC CTCATGCAGG GACCGCACCC 
CCTGCCAACC AGCTTCCCTG GCCTGTGCTG TGCTCCCCAG TGGCCGGGGT GATTCTCCTG 
GCCCTAGGGG CTCTTCTCGT CCTCCAGCTC ATCCGGCGTC GACGCCGAGA GCATGGAGCT 
CTCTGGCTGC CCCCTGGTTT CACTCGACGG CCTCGGACTC AGTCAGCTCC CCACCGACGC 
CGGCCCCCAC TAGGCGAGGA CAGCATTGGT CTCAAGGCAC TGAAGCCAAA GGCAGAAGTT 
GATGAGGATG GAGTTGTGAT GTGCTCAGGC CCTGAGGAGG GAGAGGAGGT GGGCCAGGCT 
GAAGAAACAG GCCCACCCTC CACGTGCCAG CTCTGGTCTC TGAGTGGTGG CTGTGGGGCG 
CTCCCTCAGG CAGCCATGCT AACTCCTCCC CAGGAATCTG AGATGGAAGC CCCTGACCTG 
GACACCCGTG GACCTGATGG GGTGACACCC CTGATGTCAG CAGTTTGCTG TGGGGAAGTA 
CAGTCCGGGA CCTTCCAAGG GGCATGGTTG GGATGTCCTG AGCCCTGGGA ACCTCTGCTG 
GATGGAGGGG CCTGTCCCCA GGCTCACACC GTGGGCACTG GGGAGACCCC CCTGCACCTG 
GCTGCCCGAT TCTCCCGGCC AACCGCTGCC CGCCGCCTCC TTGAGGCTGG AGCCAACCCC 
AACCAGCCAG ACCGGGCAGG GCGCACACCC CTTCATGCTG CTGTGGCTGC TGATGCTCGG 
GAGGTCTGCC AGCTTCTGCT CCGTAGCAGA CAAACTGCAG TGGACGCTCG CACAGAGGAC 
GGGACCACAC CCTTGATGCT GGCTGCCAGG CTGGCGGTGG AAGACCTGGT TGAAGAACTG 
ATTGCAGCCC AAGCAGACGT GGGGGCCAGA GATAAATGGG GGAAAACTGC GCTGCACTGG 
GCTGCTGCCG TGAACAACGC CCGAGCCGCC CGCTCGCTTC TCCAGGCCGG AGCCGATAAA 
GATGCCCAGG ACAACAGGGA GCAGACGCCG CTATTCCTGG CGGCGCGGGA AGGAGCGGTG 
GAAGTAGCCC AGCTACTGCT GGGGCTGGGG GCAGCCCGAG AGCTGCGGGA CCAGGCTGGG 
CTAGCGCCGG CGGACGTCGC TCACCAACGT AACCACTGGG ATCTGCTGAC GCTGCTGGAA 
GGGGCTGGGC CACCAGAGGC CCGTCACAAA GCCACGCCGG GCCGCGAGGC TGGGCCCTTC 
CCGCGCGCAC GGACGGTGTC AGTAAGCGTG CCCCCGCATG GGGGCGGGGC TCTGCCGCGC 
TGCCGGACGC TGTCAGCCGG AGCAGGCCCT CGTGGGGGCG GAGCTTGTCT GCAGGCTCGG 
ACTTGGTCCG TAGACTTGGC TGCGCGGGGG GGCGGGGCCT ATTCTCATTG CCGGAGCCTC 
TCGGGAGTAG GAGCAGGAGG AGGCCCGACC CCTCGCGGCC GTAGGTTTTC TGCAGGCATG 
CGCGGGCCTC GGCCCAACCC TGCGATAATG CGAGGAAGAT ACGGAGTGGC TGCCGGGCGC 
GGAGGCAGGG TCTCAACGGA TGACTGGCCC TGTGATTGGG TGGCCCTGGG AGCTTGCGGT 
TCTGCCTCCA ACATTCCGAT CCCGCCTCCT TGCCTTACTC CGTCCCCGGA GCGGGGATCA 
CCTCAACTTG ACTGTGGTCC CCCAGCCCTC CAAGAAATGC CCATAAACCA AGGAGGAGAG 
GGTAAAAAAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004548.3
CDS	140..6151
Translation	MQPPSLLLLLLLLLLLCVSVVRPRGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDCETPPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDCRPEDGDPEWGPSLALLVVLSPPALDQQLFALARVLSLTLRVGLWVRKDRDGRDMVYPYPGARAEEKLGGTRDPTYQERAAPQTQPLGKETDSLSAGFVVVMGVDLSRCGPDHPASRCPWDPGLLLRFLAAMAAVGALEPLLPGPLLAVHPHAGTAPPANQLPWPVLCSPVAGVILLALGALLVLQLIRRRRREHGALWLPPGFTRRPRTQSAPHRRRPPLGEDSIGLKALKPKAEVDEDGVVMCSGPEEGEEVGQAEETGPPSTCQLWSLSGGCGALPQAAMLTPPQESEMEAPDLDTRGPDGVTPLMSAVCCGEVQSGTFQGAWLGCPEPWEPLLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQAGLAPADVAHQRNHWDLLTLLEGAGPPEARHKATPGREAGPFPRARTVSVSVPPHGGGALPRCRTLSAGAGPRGGGACLQARTWSVDLAARGGGAYSHCRSLSGVGAGGGPTPRGRRFSAGMRGPRPNPAIMRGRYGVAAGRGGRVSTDDWPCDWVALGACGSASNIPIPPPCLTPSPERGSPQLDCGPPALQEMPINQGGEGKK

Target ORF information:

RefSeq Version	NM_004557.3
Organism	Homo sapiens(human)
Definition	Homo sapiens notch 4 (NOTCH4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004557.3

ORF Insert Sequence:

ATGCAGCCCC CTTCACTGCT GCTGCTGCTG CTGCTGCTGC TGCTGCTATG TGTCTCAGTG 
GTCAGACCCA GAGGGCTGCT GTGTGGGAGT TTCCCAGAAC CCTGTGCCAA TGGAGGCACC 
TGCCTGAGCC TGTCTCTGGG ACAAGGGACC TGCCAGTGTG CCCCTGGCTT CCTGGGTGAG 
ACGTGCCAGT TTCCTGACCC CTGCCAGAAC GCCCAGCTCT GCCAAAATGG AGGCAGCTGC 
CAAGCCCTGC TTCCCGCTCC CCTAGGGCTC CCCAGCTCTC CCTCTCCATT GACACCCAGC 
TTCTTGTGCA CTTGCCTCCC TGGCTTCACT GGTGAGAGAT GCCAGGCCAA GCTTGAAGAC 
CCTTGTCCTC CCTCCTTCTG TTCCAAAAGG GGCCGCTGCC ACATCCAGGC CTCGGGCCGC 
CCACAGTGCT CCTGCATGCC TGGATGGACA GGTGAGCAGT GCCAGCTTCG GGACTTCTGT 
TCAGCCAACC CATGTGTTAA TGGAGGGGTG TGTCTGGCCA CATACCCCCA GATCCAGTGC 
CACTGCCCAC CGGGCTTCGA GGGCCATGCC TGTGAACGTG ATGTCAACGA GTGCTTCCAG 
GACCCAGGAC CCTGCCCCAA AGGCACCTCC TGCCATAACA CCCTGGGCTC CTTCCAGTGC 
CTCTGCCCTG TGGGGCAGGA GGGTCCACGT TGTGAGCTGC GGGCAGGACC CTGCCCTCCT 
AGGGGCTGTT CGAATGGGGG CACCTGCCAG CTGATGCCAG AGAAAGACTC CACCTTTCAC 
CTCTGCCTCT GTCCCCCAGG TTTCATAGGC CCAGACTGTG AGGTGAATCC AGACAACTGT 
GTCAGCCACC AGTGTCAGAA TGGGGGCACT TGCCAGGATG GGCTGGACAC CTACACCTGC 
CTCTGCCCAG AAACCTGGAC AGGCTGGGAC TGCTCCGAAG ATGTGGATGA GTGTGAGACC 
CAGGGTCCCC CTCACTGCAG AAACGGGGGC ACCTGCCAGA ACTCTGCTGG TAGCTTTCAC 
TGCGTGTGTG TGAGTGGCTG GGGCGGCACA AGCTGTGAGG AGAACCTGGA TGACTGTATT 
GCTGCCACCT GTGCCCCGGG ATCCACCTGC ATTGACCGGG TGGGCTCTTT CTCCTGCCTC 
TGCCCACCTG GACGCACAGG ACTCCTGTGC CACTTGGAAG ACATGTGTCT GAGCCAGCCG 
TGCCATGGGG ATGCCCAATG CAGCACCAAC CCCCTCACAG GCTCCACACT CTGCCTGTGT 
CAGCCTGGCT ATTCGGGGCC CACCTGCCAC CAGGACCTGG ACGAGTGTCT GATGGCCCAG 
CAAGGCCCAA GTCCCTGTGA ACATGGCGGT TCCTGCCTCA ACACTCCTGG CTCCTTCAAC 
TGCCTCTGTC CACCTGGCTA CACAGGCTCC CGTTGTGAGG CTGATCACAA TGAGTGCCTC 
TCCCAGCCCT GCCACCCAGG AAGCACCTGT CTGGACCTAC TTGCCACCTT CCACTGCCTC 
TGCCCGCCAG GCTTAGAAGG GCAGCTCTGT GAGGTGGAGA CCAACGAGTG TGCCTCAGCT 
CCCTGCCTGA ACCACGCGGA TTGCCATGAC CTGCTCAACG GCTTCCAGTG CATCTGCCTG 
CCTGGATTCT CCGGCACCCG ATGTGAGGAG GATATCGATG AGTGCAGAAG CTCTCCCTGT 
GCCAATGGTG GGCAGTGCCA GGACCAGCCT GGAGCCTTCC ACTGCAAGTG TCTCCCAGGC 
TTTGAAGGGC CACGCTGTCA AACAGAGGTG GATGAGTGCC TGAGTGACCC ATGTCCCGTT 
GGAGCCAGCT GCCTTGATCT TCCAGGAGCC TTCTTTTGCC TCTGCCCCTC TGGTTTCACA 
GGCCAGCTCT GTGAGGTTCC CCTGTGTGCT CCCAACCTGT GCCAGCCCAA GCAGATATGT 
AAGGACCAGA AAGACAAGGC CAACTGCCTC TGTCCTGATG GAAGCCCTGG CTGTGCCCCA 
CCTGAGGACA ACTGCACCTG CCACCACGGG CACTGCCAGA GATCCTCATG TGTGTGTGAC 
GTGGGTTGGA CGGGGCCAGA GTGTGAGGCA GAGCTAGGGG GCTGCATCTC TGCACCCTGT 
GCCCATGGGG GGACCTGCTA CCCCCAGCCC TCTGGCTACA ACTGCACCTG CCCTACAGGC 
TACACAGGAC CCACCTGTAG TGAGGAGATG ACAGCTTGTC ACTCAGGGCC ATGTCTCAAT 
GGCGGCTCCT GCAACCCTAG CCCTGGAGGC TACTACTGCA CCTGCCCTCC AAGCCACACA 
GGGCCCCAGT GCCAAACCAG CACTGACTAC TGTGTGTCTG CCCCGTGCTT CAATGGGGGT 
ACCTGTGTGA ACAGGCCTGG CACCTTCTCC TGCCTCTGTG CCATGGGCTT CCAGGGCCCG 
CGCTGTGAGG GAAAGCTCCG CCCCAGCTGT GCAGACAGCC CCTGTAGGAA TAGGGCAACC 
TGCCAGGACA GCCCTCAGGG TCCCCGCTGC CTCTGCCCCA CTGGCTACAC CGGAGGCAGC 
TGCCAGACTC TGATGGACTT ATGTGCCCAG AAGCCCTGCC CACGCAATTC CCACTGCCTC 
CAGACTGGGC CCTCCTTCCA CTGCTTGTGC CTCCAGGGAT GGACCGGGCC TCTCTGCAAC 
CTTCCACTGT CCTCCTGCCA GAAGGCTGCA CTGAGCCAAG GCATAGACGT CTCTTCCCTT 
TGCCACAATG GAGGCCTCTG TGTCGACAGC GGCCCCTCCT ATTTCTGCCA CTGCCCCCCT 
GGATTCCAAG GCAGCCTGTG CCAGGATCAC GTGAACCCAT GTGAGTCCAG GCCTTGCCAG 
AACGGGGCCA CCTGCATGGC CCAGCCCAGT GGGTATCTCT GCCAGTGTGC CCCAGGCTAC 
GATGGACAGA ACTGCTCAAA GGAACTCGAT GCTTGTCAGT CCCAACCCTG TCACAACCAT 
GGAACCTGTA CTCCCAAACC TGGAGGATTC CACTGTGCCT GCCCTCCAGG CTTTGTGGGG 
CTACGCTGTG AGGGAGACGT GGACGAGTGT CTGGACCAGC CCTGCCACCC CACAGGCACT 
GCAGCCTGCC ACTCTCTGGC CAATGCCTTC TACTGCCAGT GTCTGCCTGG ACACACAGGC 
CAGTGGTGTG AGGTGGAGAT AGACCCCTGC CACAGCCAAC CCTGCTTTCA TGGAGGGACC 
TGTGAGGCCA CAGCAGGATC ACCCCTGGGT TTCATCTGCC ACTGCCCCAA GGGTTTTGAA 
GGCCCCACCT GCAGCCACAG GGCCCCTTCC TGCGGCTTCC ATCACTGCCA CCACGGAGGC 
CTGTGTCTGC CCTCCCCTAA GCCAGGCTTC CCACCACGCT GTGCCTGCCT CAGTGGCTAT 
GGGGGTCCTG ACTGCCTGAC CCCACCAGCT CCTAAAGGCT GTGGCCCTCC CTCCCCATGC 
CTATACAATG GCAGCTGCTC AGAGACCACG GGCTTGGGGG GCCCAGGCTT TCGATGCTCC 
TGCCCTCACA GCTCTCCAGG GCCCCGGTGT CAGAAACCCG GAGCCAAGGG GTGTGAGGGC 
AGAAGTGGAG ATGGGGCCTG CGATGCTGGC TGCAGTGGCC CGGGAGGAAA CTGGGATGGA 
GGGGACTGCT CTCTGGGAGT CCCAGACCCC TGGAAGGGCT GCCCCTCCCA CTCTCGGTGC 
TGGCTTCTCT TCCGGGACGG GCAGTGCCAC CCACAGTGTG ACTCTGAAGA GTGTCTGTTT 
GATGGCTACG ACTGTGAGAC CCCTCCAGCC TGCACTCCAG CCTATGACCA GTACTGCCAT 
GATCACTTCC ACAACGGGCA CTGTGAGAAA GGCTGCAACA CTGCAGAGTG TGGCTGGGAT 
GGAGGTGACT GCAGGCCTGA AGATGGGGAC CCAGAGTGGG GGCCCTCCCT GGCCCTGCTG 
GTGGTACTGA GCCCCCCAGC CCTAGACCAG CAGCTGTTTG CCCTGGCCCG GGTGCTGTCC 
CTGACTCTGA GGGTAGGACT CTGGGTAAGG AAGGATCGTG ATGGCAGGGA CATGGTGTAC 
CCCTATCCTG GGGCCCGGGC TGAAGAAAAG CTAGGAGGAA CTCGGGACCC CACCTATCAG 
GAGAGAGCAG CCCCTCAAAC GCAGCCCCTG GGCAAGGAGA CCGACTCCCT CAGTGCTGGG 
TTTGTGGTGG TCATGGGTGT GGATTTGTCC CGCTGTGGCC CTGACCACCC GGCATCCCGC 
TGTCCCTGGG ACCCTGGGCT TCTACTCCGC TTCCTTGCTG CGATGGCTGC AGTGGGAGCC 
CTGGAGCCCC TGCTGCCTGG ACCACTGCTG GCTGTCCACC CTCATGCAGG GACCGCACCC 
CCTGCCAACC AGCTTCCCTG GCCTGTGCTG TGCTCCCCAG TGGCCGGGGT GATTCTCCTG 
GCCCTAGGGG CTCTTCTCGT CCTCCAGCTC ATCCGGCGTC GACGCCGAGA GCATGGAGCT 
CTCTGGCTGC CCCCTGGTTT CACTCGACGG CCTCGGACTC AGTCAGCTCC CCACCGACGC 
CGGCCCCCAC TAGGCGAGGA CAGCATTGGT CTCAAGGCAC TGAAGCCAAA GGCAGAAGTT 
GATGAGGATG GAGTTGTGAT GTGCTCAGGC CCTGAGGAGG GAGAGGAGGT GGGCCAGGCT 
GAAGAAACAG GCCCACCCTC CACGTGCCAG CTCTGGTCTC TGAGTGGTGG CTGTGGGGCG 
CTCCCTCAGG CAGCCATGCT AACTCCTCCC CAGGAATCTG AGATGGAAGC CCCTGACCTG 
GACACCCGTG GACCTGATGG GGTGACACCC CTGATGTCAG CAGTTTGCTG TGGGGAAGTA 
CAGTCCGGGA CCTTCCAAGG GGCATGGTTG GGATGTCCTG AGCCCTGGGA ACCTCTGCTG 
GATGGAGGGG CCTGTCCCCA GGCTCACACC GTGGGCACTG GGGAGACCCC CCTGCACCTG 
GCTGCCCGAT TCTCCCGGCC AACCGCTGCC CGCCGCCTCC TTGAGGCTGG AGCCAACCCC 
AACCAGCCAG ACCGGGCAGG GCGCACACCC CTTCATGCTG CTGTGGCTGC TGATGCTCGG 
GAGGTCTGCC AGCTTCTGCT CCGTAGCAGA CAAACTGCAG TGGACGCTCG CACAGAGGAC 
GGGACCACAC CCTTGATGCT GGCTGCCAGG CTGGCGGTGG AAGACCTGGT TGAAGAACTG 
ATTGCAGCCC AAGCAGACGT GGGGGCCAGA GATAAATGGG GGAAAACTGC GCTGCACTGG 
GCTGCTGCCG TGAACAACGC CCGAGCCGCC CGCTCGCTTC TCCAGGCCGG AGCCGATAAA 
GATGCCCAGG ACAACAGGGA GCAGACGCCG CTATTCCTGG CGGCGCGGGA AGGAGCGGTG 
GAAGTAGCCC AGCTACTGCT GGGGCTGGGG GCAGCCCGAG AGCTGCGGGA CCAGGCTGGG 
CTAGCGCCGG CGGACGTCGC TCACCAACGT AACCACTGGG ATCTGCTGAC GCTGCTGGAA 
GGGGCTGGGC CACCAGAGGC CCGTCACAAA GCCACGCCGG GCCGCGAGGC TGGGCCCTTC 
CCGCGCGCAC GGACGGTGTC AGTAAGCGTG CCCCCGCATG GGGGCGGGGC TCTGCCGCGC 
TGCCGGACGC TGTCAGCCGG AGCAGGCCCT CGTGGGGGCG GAGCTTGTCT GCAGGCTCGG 
ACTTGGTCCG TAGACTTGGC TGCGCGGGGG GGCGGGGCCT ATTCTCATTG CCGGAGCCTC 
TCGGGAGTAG GAGCAGGAGG AGGCCCGACC CCTCGCGGCC GTAGGTTTTC TGCAGGCATG 
CGCGGGCCTC GGCCCAACCC TGCGATAATG CGAGGAAGAT ACGGAGTGGC TGCCGGGCGC 
GGAGGCAGGG TCTCAACGGA TGACTGGCCC TGTGATTGGG TGGCCCTGGG AGCTTGCGGT 
TCTGCCTCCA ACATTCCGAT CCCGCCTCCT TGCCTTACTC CGTCCCCGGA GCGGGGATCA 
CCTCAACTTG ACTGTGGTCC CCCAGCCCTC CAAGAAATGC CCATAAACCA AGGAGGAGAG 
GGTAAAAAAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NOTCH4 ( NM_004557.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_004548.3 Homo sapiens notch receptor 4 (NOTCH4), mRNA.

Price & Availability↑

CloneID	OHu27711
Clone ID Related Accession (Same CDS sequence)	NM_004557.3 , NM_004557.4
Accession Version	NM_004557.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 6012bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	neurogenic locus notch homolog protein 4 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL705928.1, U95299.1, D63395.1 and BQ023880.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_004557.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC140782.1, U95299.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000375023.3/ ENSP00000364163.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCAGCCCC CTTCACTGCT GCTGCTGCTG CTGCTGCTGC TGCTGCTATG TGTCTCAGTG 
GTCAGACCCA GAGGGCTGCT GTGTGGGAGT TTCCCAGAAC CCTGTGCCAA TGGAGGCACC 
TGCCTGAGCC TGTCTCTGGG ACAAGGGACC TGCCAGTGTG CCCCTGGCTT CCTGGGTGAG 
ACGTGCCAGT TTCCTGACCC CTGCCAGAAC GCCCAGCTCT GCCAAAATGG AGGCAGCTGC 
CAAGCCCTGC TTCCCGCTCC CCTAGGGCTC CCCAGCTCTC CCTCTCCATT GACACCCAGC 
TTCTTGTGCA CTTGCCTCCC TGGCTTCACT GGTGAGAGAT GCCAGGCCAA GCTTGAAGAC 
CCTTGTCCTC CCTCCTTCTG TTCCAAAAGG GGCCGCTGCC ACATCCAGGC CTCGGGCCGC 
CCACAGTGCT CCTGCATGCC TGGATGGACA GGTGAGCAGT GCCAGCTTCG GGACTTCTGT 
TCAGCCAACC CATGTGTTAA TGGAGGGGTG TGTCTGGCCA CATACCCCCA GATCCAGTGC 
CACTGCCCAC CGGGCTTCGA GGGCCATGCC TGTGAACGTG ATGTCAACGA GTGCTTCCAG 
GACCCAGGAC CCTGCCCCAA AGGCACCTCC TGCCATAACA CCCTGGGCTC CTTCCAGTGC 
CTCTGCCCTG TGGGGCAGGA GGGTCCACGT TGTGAGCTGC GGGCAGGACC CTGCCCTCCT 
AGGGGCTGTT CGAATGGGGG CACCTGCCAG CTGATGCCAG AGAAAGACTC CACCTTTCAC 
CTCTGCCTCT GTCCCCCAGG TTTCATAGGC CCAGACTGTG AGGTGAATCC AGACAACTGT 
GTCAGCCACC AGTGTCAGAA TGGGGGCACT TGCCAGGATG GGCTGGACAC CTACACCTGC 
CTCTGCCCAG AAACCTGGAC AGGCTGGGAC TGCTCCGAAG ATGTGGATGA GTGTGAGACC 
CAGGGTCCCC CTCACTGCAG AAACGGGGGC ACCTGCCAGA ACTCTGCTGG TAGCTTTCAC 
TGCGTGTGTG TGAGTGGCTG GGGCGGCACA AGCTGTGAGG AGAACCTGGA TGACTGTATT 
GCTGCCACCT GTGCCCCGGG ATCCACCTGC ATTGACCGGG TGGGCTCTTT CTCCTGCCTC 
TGCCCACCTG GACGCACAGG ACTCCTGTGC CACTTGGAAG ACATGTGTCT GAGCCAGCCG 
TGCCATGGGG ATGCCCAATG CAGCACCAAC CCCCTCACAG GCTCCACACT CTGCCTGTGT 
CAGCCTGGCT ATTCGGGGCC CACCTGCCAC CAGGACCTGG ACGAGTGTCT GATGGCCCAG 
CAAGGCCCAA GTCCCTGTGA ACATGGCGGT TCCTGCCTCA ACACTCCTGG CTCCTTCAAC 
TGCCTCTGTC CACCTGGCTA CACAGGCTCC CGTTGTGAGG CTGATCACAA TGAGTGCCTC 
TCCCAGCCCT GCCACCCAGG AAGCACCTGT CTGGACCTAC TTGCCACCTT CCACTGCCTC 
TGCCCGCCAG GCTTAGAAGG GCAGCTCTGT GAGGTGGAGA CCAACGAGTG TGCCTCAGCT 
CCCTGCCTGA ACCACGCGGA TTGCCATGAC CTGCTCAACG GCTTCCAGTG CATCTGCCTG 
CCTGGATTCT CCGGCACCCG ATGTGAGGAG GATATCGATG AGTGCAGAAG CTCTCCCTGT 
GCCAATGGTG GGCAGTGCCA GGACCAGCCT GGAGCCTTCC ACTGCAAGTG TCTCCCAGGC 
TTTGAAGGGC CACGCTGTCA AACAGAGGTG GATGAGTGCC TGAGTGACCC ATGTCCCGTT 
GGAGCCAGCT GCCTTGATCT TCCAGGAGCC TTCTTTTGCC TCTGCCCCTC TGGTTTCACA 
GGCCAGCTCT GTGAGGTTCC CCTGTGTGCT CCCAACCTGT GCCAGCCCAA GCAGATATGT 
AAGGACCAGA AAGACAAGGC CAACTGCCTC TGTCCTGATG GAAGCCCTGG CTGTGCCCCA 
CCTGAGGACA ACTGCACCTG CCACCACGGG CACTGCCAGA GATCCTCATG TGTGTGTGAC 
GTGGGTTGGA CGGGGCCAGA GTGTGAGGCA GAGCTAGGGG GCTGCATCTC TGCACCCTGT 
GCCCATGGGG GGACCTGCTA CCCCCAGCCC TCTGGCTACA ACTGCACCTG CCCTACAGGC 
TACACAGGAC CCACCTGTAG TGAGGAGATG ACAGCTTGTC ACTCAGGGCC ATGTCTCAAT 
GGCGGCTCCT GCAACCCTAG CCCTGGAGGC TACTACTGCA CCTGCCCTCC AAGCCACACA 
GGGCCCCAGT GCCAAACCAG CACTGACTAC TGTGTGTCTG CCCCGTGCTT CAATGGGGGT 
ACCTGTGTGA ACAGGCCTGG CACCTTCTCC TGCCTCTGTG CCATGGGCTT CCAGGGCCCG 
CGCTGTGAGG GAAAGCTCCG CCCCAGCTGT GCAGACAGCC CCTGTAGGAA TAGGGCAACC 
TGCCAGGACA GCCCTCAGGG TCCCCGCTGC CTCTGCCCCA CTGGCTACAC CGGAGGCAGC 
TGCCAGACTC TGATGGACTT ATGTGCCCAG AAGCCCTGCC CACGCAATTC CCACTGCCTC 
CAGACTGGGC CCTCCTTCCA CTGCTTGTGC CTCCAGGGAT GGACCGGGCC TCTCTGCAAC 
CTTCCACTGT CCTCCTGCCA GAAGGCTGCA CTGAGCCAAG GCATAGACGT CTCTTCCCTT 
TGCCACAATG GAGGCCTCTG TGTCGACAGC GGCCCCTCCT ATTTCTGCCA CTGCCCCCCT 
GGATTCCAAG GCAGCCTGTG CCAGGATCAC GTGAACCCAT GTGAGTCCAG GCCTTGCCAG 
AACGGGGCCA CCTGCATGGC CCAGCCCAGT GGGTATCTCT GCCAGTGTGC CCCAGGCTAC 
GATGGACAGA ACTGCTCAAA GGAACTCGAT GCTTGTCAGT CCCAACCCTG TCACAACCAT 
GGAACCTGTA CTCCCAAACC TGGAGGATTC CACTGTGCCT GCCCTCCAGG CTTTGTGGGG 
CTACGCTGTG AGGGAGACGT GGACGAGTGT CTGGACCAGC CCTGCCACCC CACAGGCACT 
GCAGCCTGCC ACTCTCTGGC CAATGCCTTC TACTGCCAGT GTCTGCCTGG ACACACAGGC 
CAGTGGTGTG AGGTGGAGAT AGACCCCTGC CACAGCCAAC CCTGCTTTCA TGGAGGGACC 
TGTGAGGCCA CAGCAGGATC ACCCCTGGGT TTCATCTGCC ACTGCCCCAA GGGTTTTGAA 
GGCCCCACCT GCAGCCACAG GGCCCCTTCC TGCGGCTTCC ATCACTGCCA CCACGGAGGC 
CTGTGTCTGC CCTCCCCTAA GCCAGGCTTC CCACCACGCT GTGCCTGCCT CAGTGGCTAT 
GGGGGTCCTG ACTGCCTGAC CCCACCAGCT CCTAAAGGCT GTGGCCCTCC CTCCCCATGC 
CTATACAATG GCAGCTGCTC AGAGACCACG GGCTTGGGGG GCCCAGGCTT TCGATGCTCC 
TGCCCTCACA GCTCTCCAGG GCCCCGGTGT CAGAAACCCG GAGCCAAGGG GTGTGAGGGC 
AGAAGTGGAG ATGGGGCCTG CGATGCTGGC TGCAGTGGCC CGGGAGGAAA CTGGGATGGA 
GGGGACTGCT CTCTGGGAGT CCCAGACCCC TGGAAGGGCT GCCCCTCCCA CTCTCGGTGC 
TGGCTTCTCT TCCGGGACGG GCAGTGCCAC CCACAGTGTG ACTCTGAAGA GTGTCTGTTT 
GATGGCTACG ACTGTGAGAC CCCTCCAGCC TGCACTCCAG CCTATGACCA GTACTGCCAT 
GATCACTTCC ACAACGGGCA CTGTGAGAAA GGCTGCAACA CTGCAGAGTG TGGCTGGGAT 
GGAGGTGACT GCAGGCCTGA AGATGGGGAC CCAGAGTGGG GGCCCTCCCT GGCCCTGCTG 
GTGGTACTGA GCCCCCCAGC CCTAGACCAG CAGCTGTTTG CCCTGGCCCG GGTGCTGTCC 
CTGACTCTGA GGGTAGGACT CTGGGTAAGG AAGGATCGTG ATGGCAGGGA CATGGTGTAC 
CCCTATCCTG GGGCCCGGGC TGAAGAAAAG CTAGGAGGAA CTCGGGACCC CACCTATCAG 
GAGAGAGCAG CCCCTCAAAC GCAGCCCCTG GGCAAGGAGA CCGACTCCCT CAGTGCTGGG 
TTTGTGGTGG TCATGGGTGT GGATTTGTCC CGCTGTGGCC CTGACCACCC GGCATCCCGC 
TGTCCCTGGG ACCCTGGGCT TCTACTCCGC TTCCTTGCTG CGATGGCTGC AGTGGGAGCC 
CTGGAGCCCC TGCTGCCTGG ACCACTGCTG GCTGTCCACC CTCATGCAGG GACCGCACCC 
CCTGCCAACC AGCTTCCCTG GCCTGTGCTG TGCTCCCCAG TGGCCGGGGT GATTCTCCTG 
GCCCTAGGGG CTCTTCTCGT CCTCCAGCTC ATCCGGCGTC GACGCCGAGA GCATGGAGCT 
CTCTGGCTGC CCCCTGGTTT CACTCGACGG CCTCGGACTC AGTCAGCTCC CCACCGACGC 
CGGCCCCCAC TAGGCGAGGA CAGCATTGGT CTCAAGGCAC TGAAGCCAAA GGCAGAAGTT 
GATGAGGATG GAGTTGTGAT GTGCTCAGGC CCTGAGGAGG GAGAGGAGGT GGGCCAGGCT 
GAAGAAACAG GCCCACCCTC CACGTGCCAG CTCTGGTCTC TGAGTGGTGG CTGTGGGGCG 
CTCCCTCAGG CAGCCATGCT AACTCCTCCC CAGGAATCTG AGATGGAAGC CCCTGACCTG 
GACACCCGTG GACCTGATGG GGTGACACCC CTGATGTCAG CAGTTTGCTG TGGGGAAGTA 
CAGTCCGGGA CCTTCCAAGG GGCATGGTTG GGATGTCCTG AGCCCTGGGA ACCTCTGCTG 
GATGGAGGGG CCTGTCCCCA GGCTCACACC GTGGGCACTG GGGAGACCCC CCTGCACCTG 
GCTGCCCGAT TCTCCCGGCC AACCGCTGCC CGCCGCCTCC TTGAGGCTGG AGCCAACCCC 
AACCAGCCAG ACCGGGCAGG GCGCACACCC CTTCATGCTG CTGTGGCTGC TGATGCTCGG 
GAGGTCTGCC AGCTTCTGCT CCGTAGCAGA CAAACTGCAG TGGACGCTCG CACAGAGGAC 
GGGACCACAC CCTTGATGCT GGCTGCCAGG CTGGCGGTGG AAGACCTGGT TGAAGAACTG 
ATTGCAGCCC AAGCAGACGT GGGGGCCAGA GATAAATGGG GGAAAACTGC GCTGCACTGG 
GCTGCTGCCG TGAACAACGC CCGAGCCGCC CGCTCGCTTC TCCAGGCCGG AGCCGATAAA 
GATGCCCAGG ACAACAGGGA GCAGACGCCG CTATTCCTGG CGGCGCGGGA AGGAGCGGTG 
GAAGTAGCCC AGCTACTGCT GGGGCTGGGG GCAGCCCGAG AGCTGCGGGA CCAGGCTGGG 
CTAGCGCCGG CGGACGTCGC TCACCAACGT AACCACTGGG ATCTGCTGAC GCTGCTGGAA 
GGGGCTGGGC CACCAGAGGC CCGTCACAAA GCCACGCCGG GCCGCGAGGC TGGGCCCTTC 
CCGCGCGCAC GGACGGTGTC AGTAAGCGTG CCCCCGCATG GGGGCGGGGC TCTGCCGCGC 
TGCCGGACGC TGTCAGCCGG AGCAGGCCCT CGTGGGGGCG GAGCTTGTCT GCAGGCTCGG 
ACTTGGTCCG TAGACTTGGC TGCGCGGGGG GGCGGGGCCT ATTCTCATTG CCGGAGCCTC 
TCGGGAGTAG GAGCAGGAGG AGGCCCGACC CCTCGCGGCC GTAGGTTTTC TGCAGGCATG 
CGCGGGCCTC GGCCCAACCC TGCGATAATG CGAGGAAGAT ACGGAGTGGC TGCCGGGCGC 
GGAGGCAGGG TCTCAACGGA TGACTGGCCC TGTGATTGGG TGGCCCTGGG AGCTTGCGGT 
TCTGCCTCCA ACATTCCGAT CCCGCCTCCT TGCCTTACTC CGTCCCCGGA GCGGGGATCA 
CCTCAACTTG ACTGTGGTCC CCCAGCCCTC CAAGAAATGC CCATAAACCA AGGAGGAGAG 
GGTAAAAAAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004548.3
CDS	140..6151
Translation	MQPPSLLLLLLLLLLLCVSVVRPRGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDCETPPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDCRPEDGDPEWGPSLALLVVLSPPALDQQLFALARVLSLTLRVGLWVRKDRDGRDMVYPYPGARAEEKLGGTRDPTYQERAAPQTQPLGKETDSLSAGFVVVMGVDLSRCGPDHPASRCPWDPGLLLRFLAAMAAVGALEPLLPGPLLAVHPHAGTAPPANQLPWPVLCSPVAGVILLALGALLVLQLIRRRRREHGALWLPPGFTRRPRTQSAPHRRRPPLGEDSIGLKALKPKAEVDEDGVVMCSGPEEGEEVGQAEETGPPSTCQLWSLSGGCGALPQAAMLTPPQESEMEAPDLDTRGPDGVTPLMSAVCCGEVQSGTFQGAWLGCPEPWEPLLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQAGLAPADVAHQRNHWDLLTLLEGAGPPEARHKATPGREAGPFPRARTVSVSVPPHGGGALPRCRTLSAGAGPRGGGACLQARTWSVDLAARGGGAYSHCRSLSGVGAGGGPTPRGRRFSAGMRGPRPNPAIMRGRYGVAAGRGGRVSTDDWPCDWVALGACGSASNIPIPPPCLTPSPERGSPQLDCGPPALQEMPINQGGEGKK

Target ORF information:

RefSeq Version	NM_004557.4
Organism	Homo sapiens(human)
Definition	Homo sapiens notch receptor 4 (NOTCH4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004557.4

ORF Insert Sequence:

ATGCAGCCCC CTTCACTGCT GCTGCTGCTG CTGCTGCTGC TGCTGCTATG TGTCTCAGTG 
GTCAGACCCA GAGGGCTGCT GTGTGGGAGT TTCCCAGAAC CCTGTGCCAA TGGAGGCACC 
TGCCTGAGCC TGTCTCTGGG ACAAGGGACC TGCCAGTGTG CCCCTGGCTT CCTGGGTGAG 
ACGTGCCAGT TTCCTGACCC CTGCCAGAAC GCCCAGCTCT GCCAAAATGG AGGCAGCTGC 
CAAGCCCTGC TTCCCGCTCC CCTAGGGCTC CCCAGCTCTC CCTCTCCATT GACACCCAGC 
TTCTTGTGCA CTTGCCTCCC TGGCTTCACT GGTGAGAGAT GCCAGGCCAA GCTTGAAGAC 
CCTTGTCCTC CCTCCTTCTG TTCCAAAAGG GGCCGCTGCC ACATCCAGGC CTCGGGCCGC 
CCACAGTGCT CCTGCATGCC TGGATGGACA GGTGAGCAGT GCCAGCTTCG GGACTTCTGT 
TCAGCCAACC CATGTGTTAA TGGAGGGGTG TGTCTGGCCA CATACCCCCA GATCCAGTGC 
CACTGCCCAC CGGGCTTCGA GGGCCATGCC TGTGAACGTG ATGTCAACGA GTGCTTCCAG 
GACCCAGGAC CCTGCCCCAA AGGCACCTCC TGCCATAACA CCCTGGGCTC CTTCCAGTGC 
CTCTGCCCTG TGGGGCAGGA GGGTCCACGT TGTGAGCTGC GGGCAGGACC CTGCCCTCCT 
AGGGGCTGTT CGAATGGGGG CACCTGCCAG CTGATGCCAG AGAAAGACTC CACCTTTCAC 
CTCTGCCTCT GTCCCCCAGG TTTCATAGGC CCAGACTGTG AGGTGAATCC AGACAACTGT 
GTCAGCCACC AGTGTCAGAA TGGGGGCACT TGCCAGGATG GGCTGGACAC CTACACCTGC 
CTCTGCCCAG AAACCTGGAC AGGCTGGGAC TGCTCCGAAG ATGTGGATGA GTGTGAGACC 
CAGGGTCCCC CTCACTGCAG AAACGGGGGC ACCTGCCAGA ACTCTGCTGG TAGCTTTCAC 
TGCGTGTGTG TGAGTGGCTG GGGCGGCACA AGCTGTGAGG AGAACCTGGA TGACTGTATT 
GCTGCCACCT GTGCCCCGGG ATCCACCTGC ATTGACCGGG TGGGCTCTTT CTCCTGCCTC 
TGCCCACCTG GACGCACAGG ACTCCTGTGC CACTTGGAAG ACATGTGTCT GAGCCAGCCG 
TGCCATGGGG ATGCCCAATG CAGCACCAAC CCCCTCACAG GCTCCACACT CTGCCTGTGT 
CAGCCTGGCT ATTCGGGGCC CACCTGCCAC CAGGACCTGG ACGAGTGTCT GATGGCCCAG 
CAAGGCCCAA GTCCCTGTGA ACATGGCGGT TCCTGCCTCA ACACTCCTGG CTCCTTCAAC 
TGCCTCTGTC CACCTGGCTA CACAGGCTCC CGTTGTGAGG CTGATCACAA TGAGTGCCTC 
TCCCAGCCCT GCCACCCAGG AAGCACCTGT CTGGACCTAC TTGCCACCTT CCACTGCCTC 
TGCCCGCCAG GCTTAGAAGG GCAGCTCTGT GAGGTGGAGA CCAACGAGTG TGCCTCAGCT 
CCCTGCCTGA ACCACGCGGA TTGCCATGAC CTGCTCAACG GCTTCCAGTG CATCTGCCTG 
CCTGGATTCT CCGGCACCCG ATGTGAGGAG GATATCGATG AGTGCAGAAG CTCTCCCTGT 
GCCAATGGTG GGCAGTGCCA GGACCAGCCT GGAGCCTTCC ACTGCAAGTG TCTCCCAGGC 
TTTGAAGGGC CACGCTGTCA AACAGAGGTG GATGAGTGCC TGAGTGACCC ATGTCCCGTT 
GGAGCCAGCT GCCTTGATCT TCCAGGAGCC TTCTTTTGCC TCTGCCCCTC TGGTTTCACA 
GGCCAGCTCT GTGAGGTTCC CCTGTGTGCT CCCAACCTGT GCCAGCCCAA GCAGATATGT 
AAGGACCAGA AAGACAAGGC CAACTGCCTC TGTCCTGATG GAAGCCCTGG CTGTGCCCCA 
CCTGAGGACA ACTGCACCTG CCACCACGGG CACTGCCAGA GATCCTCATG TGTGTGTGAC 
GTGGGTTGGA CGGGGCCAGA GTGTGAGGCA GAGCTAGGGG GCTGCATCTC TGCACCCTGT 
GCCCATGGGG GGACCTGCTA CCCCCAGCCC TCTGGCTACA ACTGCACCTG CCCTACAGGC 
TACACAGGAC CCACCTGTAG TGAGGAGATG ACAGCTTGTC ACTCAGGGCC ATGTCTCAAT 
GGCGGCTCCT GCAACCCTAG CCCTGGAGGC TACTACTGCA CCTGCCCTCC AAGCCACACA 
GGGCCCCAGT GCCAAACCAG CACTGACTAC TGTGTGTCTG CCCCGTGCTT CAATGGGGGT 
ACCTGTGTGA ACAGGCCTGG CACCTTCTCC TGCCTCTGTG CCATGGGCTT CCAGGGCCCG 
CGCTGTGAGG GAAAGCTCCG CCCCAGCTGT GCAGACAGCC CCTGTAGGAA TAGGGCAACC 
TGCCAGGACA GCCCTCAGGG TCCCCGCTGC CTCTGCCCCA CTGGCTACAC CGGAGGCAGC 
TGCCAGACTC TGATGGACTT ATGTGCCCAG AAGCCCTGCC CACGCAATTC CCACTGCCTC 
CAGACTGGGC CCTCCTTCCA CTGCTTGTGC CTCCAGGGAT GGACCGGGCC TCTCTGCAAC 
CTTCCACTGT CCTCCTGCCA GAAGGCTGCA CTGAGCCAAG GCATAGACGT CTCTTCCCTT 
TGCCACAATG GAGGCCTCTG TGTCGACAGC GGCCCCTCCT ATTTCTGCCA CTGCCCCCCT 
GGATTCCAAG GCAGCCTGTG CCAGGATCAC GTGAACCCAT GTGAGTCCAG GCCTTGCCAG 
AACGGGGCCA CCTGCATGGC CCAGCCCAGT GGGTATCTCT GCCAGTGTGC CCCAGGCTAC 
GATGGACAGA ACTGCTCAAA GGAACTCGAT GCTTGTCAGT CCCAACCCTG TCACAACCAT 
GGAACCTGTA CTCCCAAACC TGGAGGATTC CACTGTGCCT GCCCTCCAGG CTTTGTGGGG 
CTACGCTGTG AGGGAGACGT GGACGAGTGT CTGGACCAGC CCTGCCACCC CACAGGCACT 
GCAGCCTGCC ACTCTCTGGC CAATGCCTTC TACTGCCAGT GTCTGCCTGG ACACACAGGC 
CAGTGGTGTG AGGTGGAGAT AGACCCCTGC CACAGCCAAC CCTGCTTTCA TGGAGGGACC 
TGTGAGGCCA CAGCAGGATC ACCCCTGGGT TTCATCTGCC ACTGCCCCAA GGGTTTTGAA 
GGCCCCACCT GCAGCCACAG GGCCCCTTCC TGCGGCTTCC ATCACTGCCA CCACGGAGGC 
CTGTGTCTGC CCTCCCCTAA GCCAGGCTTC CCACCACGCT GTGCCTGCCT CAGTGGCTAT 
GGGGGTCCTG ACTGCCTGAC CCCACCAGCT CCTAAAGGCT GTGGCCCTCC CTCCCCATGC 
CTATACAATG GCAGCTGCTC AGAGACCACG GGCTTGGGGG GCCCAGGCTT TCGATGCTCC 
TGCCCTCACA GCTCTCCAGG GCCCCGGTGT CAGAAACCCG GAGCCAAGGG GTGTGAGGGC 
AGAAGTGGAG ATGGGGCCTG CGATGCTGGC TGCAGTGGCC CGGGAGGAAA CTGGGATGGA 
GGGGACTGCT CTCTGGGAGT CCCAGACCCC TGGAAGGGCT GCCCCTCCCA CTCTCGGTGC 
TGGCTTCTCT TCCGGGACGG GCAGTGCCAC CCACAGTGTG ACTCTGAAGA GTGTCTGTTT 
GATGGCTACG ACTGTGAGAC CCCTCCAGCC TGCACTCCAG CCTATGACCA GTACTGCCAT 
GATCACTTCC ACAACGGGCA CTGTGAGAAA GGCTGCAACA CTGCAGAGTG TGGCTGGGAT 
GGAGGTGACT GCAGGCCTGA AGATGGGGAC CCAGAGTGGG GGCCCTCCCT GGCCCTGCTG 
GTGGTACTGA GCCCCCCAGC CCTAGACCAG CAGCTGTTTG CCCTGGCCCG GGTGCTGTCC 
CTGACTCTGA GGGTAGGACT CTGGGTAAGG AAGGATCGTG ATGGCAGGGA CATGGTGTAC 
CCCTATCCTG GGGCCCGGGC TGAAGAAAAG CTAGGAGGAA CTCGGGACCC CACCTATCAG 
GAGAGAGCAG CCCCTCAAAC GCAGCCCCTG GGCAAGGAGA CCGACTCCCT CAGTGCTGGG 
TTTGTGGTGG TCATGGGTGT GGATTTGTCC CGCTGTGGCC CTGACCACCC GGCATCCCGC 
TGTCCCTGGG ACCCTGGGCT TCTACTCCGC TTCCTTGCTG CGATGGCTGC AGTGGGAGCC 
CTGGAGCCCC TGCTGCCTGG ACCACTGCTG GCTGTCCACC CTCATGCAGG GACCGCACCC 
CCTGCCAACC AGCTTCCCTG GCCTGTGCTG TGCTCCCCAG TGGCCGGGGT GATTCTCCTG 
GCCCTAGGGG CTCTTCTCGT CCTCCAGCTC ATCCGGCGTC GACGCCGAGA GCATGGAGCT 
CTCTGGCTGC CCCCTGGTTT CACTCGACGG CCTCGGACTC AGTCAGCTCC CCACCGACGC 
CGGCCCCCAC TAGGCGAGGA CAGCATTGGT CTCAAGGCAC TGAAGCCAAA GGCAGAAGTT 
GATGAGGATG GAGTTGTGAT GTGCTCAGGC CCTGAGGAGG GAGAGGAGGT GGGCCAGGCT 
GAAGAAACAG GCCCACCCTC CACGTGCCAG CTCTGGTCTC TGAGTGGTGG CTGTGGGGCG 
CTCCCTCAGG CAGCCATGCT AACTCCTCCC CAGGAATCTG AGATGGAAGC CCCTGACCTG 
GACACCCGTG GACCTGATGG GGTGACACCC CTGATGTCAG CAGTTTGCTG TGGGGAAGTA 
CAGTCCGGGA CCTTCCAAGG GGCATGGTTG GGATGTCCTG AGCCCTGGGA ACCTCTGCTG 
GATGGAGGGG CCTGTCCCCA GGCTCACACC GTGGGCACTG GGGAGACCCC CCTGCACCTG 
GCTGCCCGAT TCTCCCGGCC AACCGCTGCC CGCCGCCTCC TTGAGGCTGG AGCCAACCCC 
AACCAGCCAG ACCGGGCAGG GCGCACACCC CTTCATGCTG CTGTGGCTGC TGATGCTCGG 
GAGGTCTGCC AGCTTCTGCT CCGTAGCAGA CAAACTGCAG TGGACGCTCG CACAGAGGAC 
GGGACCACAC CCTTGATGCT GGCTGCCAGG CTGGCGGTGG AAGACCTGGT TGAAGAACTG 
ATTGCAGCCC AAGCAGACGT GGGGGCCAGA GATAAATGGG GGAAAACTGC GCTGCACTGG 
GCTGCTGCCG TGAACAACGC CCGAGCCGCC CGCTCGCTTC TCCAGGCCGG AGCCGATAAA 
GATGCCCAGG ACAACAGGGA GCAGACGCCG CTATTCCTGG CGGCGCGGGA AGGAGCGGTG 
GAAGTAGCCC AGCTACTGCT GGGGCTGGGG GCAGCCCGAG AGCTGCGGGA CCAGGCTGGG 
CTAGCGCCGG CGGACGTCGC TCACCAACGT AACCACTGGG ATCTGCTGAC GCTGCTGGAA 
GGGGCTGGGC CACCAGAGGC CCGTCACAAA GCCACGCCGG GCCGCGAGGC TGGGCCCTTC 
CCGCGCGCAC GGACGGTGTC AGTAAGCGTG CCCCCGCATG GGGGCGGGGC TCTGCCGCGC 
TGCCGGACGC TGTCAGCCGG AGCAGGCCCT CGTGGGGGCG GAGCTTGTCT GCAGGCTCGG 
ACTTGGTCCG TAGACTTGGC TGCGCGGGGG GGCGGGGCCT ATTCTCATTG CCGGAGCCTC 
TCGGGAGTAG GAGCAGGAGG AGGCCCGACC CCTCGCGGCC GTAGGTTTTC TGCAGGCATG 
CGCGGGCCTC GGCCCAACCC TGCGATAATG CGAGGAAGAT ACGGAGTGGC TGCCGGGCGC 
GGAGGCAGGG TCTCAACGGA TGACTGGCCC TGTGATTGGG TGGCCCTGGG AGCTTGCGGT 
TCTGCCTCCA ACATTCCGAT CCCGCCTCCT TGCCTTACTC CGTCCCCGGA GCGGGGATCA 
CCTCAACTTG ACTGTGGTCC CCCAGCCCTC CAAGAAATGC CCATAAACCA AGGAGGAGAG 
GGTAAAAAAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Human
Blood131(2)191-201(2018 Jan)
Li Y,Jin C,Bai H,Gao Y,Sun S,Chen L,Qin L,Liu PP,Cheng L,Wang QF

The
Clinical cancer research : an official journal of the American Association for Cancer Research(2017 Nov)
Fukusumi T,Guo TW,Sakai A,Ando M,Ren S,Haft S,Liu C,Amornphimoltham P,Gutkind JS,Califano JA

Downregulation of Notch4 - a prognostic marker in distinguishing oral verrucous carcinoma from oral squamous cell carcinoma.
Brazilian journal of otorhinolaryngology(2017 Oct)
Harishankar MK,Mohan AM,Krishnan AV,Devi A

Prognostic roles of mRNA expression of notch receptors in non-small cell lung cancer.
Oncotarget8(8)13157-13165(2017 Feb)
Xiong J,Zhang X,Chen X,Wei Y,Lu DG,Han YW,Xu J,Yu D

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

NOTCH4 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報