NDUFA8 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	NDUFA8
Entrez Gene ID	4702
Full Name	NADH:ubiquinone oxidoreductase subunit A8
Synonyms	CI-19KD,CI-PGIV,PGIV
General protein information	Preferred Names NADH:ubiquinone oxidoreductase subunit A8 Names NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa NADH-ubiquinone oxidoreductase 19 kDa subunit NADH:ubiquinone oxidoreductase PGIV subunit complex I-19kD complex I-PGIV
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 9 Map Location: 9q33.2
Summary	The protein encoded by this gene belongs to the complex I 19 kDa subunit family. Mammalian complex I is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase activity. It plays an important role in transfering electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015].
Disorder MIM:	603359

mRNA and Protein(s)

mRNA	Protein	Name
NM_001318195.1	NP_001305124.1	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 isoform 2
NM_001318195.2	NP_001305124.1	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 isoform 2
NM_014222.2	NP_055037.1	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 isoform 1
NM_014222.3	NP_055037.1	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 isoform 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	NDUFA8	NP_055037.1
Canis lupus familiaris (dog)	NDUFA8	XP_537861.1
Rattus norvegicus (Norway rat)	Ndufa8	NP_001041327.1
Gallus gallus (chicken)	NDUFA8	NP_001264584.1
Drosophila melanogaster (fruit fly)	CG3683	NP_001163296.1
Caenorhabditis elegans (roundworm)	Y54F10AM.5	NP_497574.2
Xenopus tropicalis (tropical clawed frog)	ndufa8	NP_001096491.1
Bos taurus (cattle)	NDUFA8	NP_787020.1
Mus musculus (house mouse)	Ndufa8	NP_080979.1
Pan troglodytes (chimpanzee)	NDUFA8	NP_001065268.1
	NDUFA8	XP_001089493.1
Danio rerio (zebrafish)	ndufa8	NP_957021.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006918	XP_308839.2

Gene Ontology
Bibliography

Related articles in PubMed

Accessory subunits are integral for assembly and function of human mitochondrial complex I.
Stroud DA, Surgenor EE, Formosa LE, Reljic B, Frazier AE, Dibley MG, Osellame LD, Stait T, Beilharz TH, Thorburn DR, Salim A, Ryan MT
Nature538(7623)123-126(2016 Oct)

Mitochondrial Protein Interaction Mapping Identifies Regulators of Respiratory Chain Function.
Floyd BJ, Wilkerson EM, Veling MT, Minogue CE, Xia C, Beebe ET, Wrobel RL, Cho H, Kremer LS, Alston CL, Gromek KA, Dolan BK, Ulbrich A, Stefely JA, Bohl SL, Werner KM, Jochem A, Westphall MS, Rensvold JW, Taylor RW, Prokisch H, Kim JP, Coon JJ, Pagliarini DJ
Molecular cell63(4)621-632(2016 Aug)

Protein import and oxidative folding in the mitochondrial intermembrane space of intact mammalian cells.
Fischer M, Horn S, Belkacemi A, Kojer K, Petrungaro C, Habich M, Ali M, K?ttner V, Bien M, Kauff F, Dengjel J, Herrmann JM, Riemer J
Molecular biology of the cell24(14)2160-70(2013 Jul)

KIF14 negatively regulates Rap1a-Radil signaling during breast cancer progression.
Ahmed SM, Th?riault BL, Uppalapati M, Chiu CW, Gallie BL, Sidhu SS, Angers S
The Journal of cell biology199(6)951-67(2012 Dec)

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
Comuzzie AG, Cole SA, Laston SL, Voruganti VS, Haack K, Gibbs RA, Butte NF
PloS one7(12)e51954(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Intra-molecular disulfide bridges and the inter-membrane space localization of three Cx(9)C-containing subunits in human: NDUFS5, NDUFB7 and NDUFA8, are proposed.
Title: NDUFB7 and NDUFA8 are located at the intermembrane surface of complex I.

Observational study of gene-disease association. (HuGE Navigator)
Title: Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

Observational study of gene-disease association. (HuGE Navigator)
Title: Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.

Observational study of gene-disease association. (HuGE Navigator)
Title: Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey.

The following NDUFA8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NDUFA8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu55765	NM_014222.3 Latest version!	Homo sapiens NADH:ubiquinone oxidoreductase subunit A8 (NDUFA8), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu43297	NM_001318195.2 Latest version!	Homo sapiens NADH:ubiquinone oxidoreductase subunit A8 (NDUFA8), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu43297	NM_001318195.1	Homo sapiens NADH:ubiquinone oxidoreductase subunit A8 (NDUFA8), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu55765	NM_014222.2	Homo sapiens NADH:ubiquinone oxidoreductase subunit A8 (NDUFA8), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

NDUFA8 ( NM_014222.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_055037.1 Homo sapiens NADH:ubiquinone oxidoreductase subunit A8 (NDUFA8), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu55765
Clone ID Related Accession (Same CDS sequence)	NM_014222.2 , NM_014222.3
Accession Version	NM_014222.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 519bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK314135.1 and BC001016.2. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_014222.2. Transcript Variant: This variant (1) represents the shorter transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189661.4286.1, SRR5189664.130104.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta MANE Ensembl match :: ENST00000373768.4/ ENSP00000362873.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCCGGGGA TAGTGGAGCT GCCCACTCTA GAGGAGCTGA AAGTAGATGA GGTGAAAATT 
AGTTCTGCTG TGCTTAAAGC TGCGGCCCAT CACTATGGAG CTCAATGTGA TAAGCCCAAC 
AAGGAGTTTA TGCTCTGCCG CTGGGAAGAG AAAGATCCGA GGCGGTGTTT AGAGGAAGGC 
AAACTGGTCA ACAAGTGTGC TTTGGACTTC TTTAGGCAGA TAAAACGTCA CTGTGCAGAG 
CCTTTTACAG AATATTGGAC TTGCATTGAT TATACTGGCC AGCAGTTATT TCGTCACTGT 
CGCAAACAGC AGGCAAAGTT TGACGAGTGT GTGCTGGACA AACTGGGCTG GGTGCGGCCT 
GACCTGGGAG AACTGTCAAA GGTCACCAAA GTGAAAACAG ATCGACCTTT ACCGGAGAAT 
CCCTATCACT CAAGACCAAG ACCGGATCCC AGCCCTGAGA TCGAGGGAGA TCTGCAGCCT 
GCCACACATG GCAGCCGCTT TTATTTCTGG ACCAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055037.1
CDS	103..621
Translation	MPGIVELPTLEELKVDEVKISSAVLKAAAHHYGAQCDKPNKEFMLCRWEEKDPRRCLEEGKLVNKCALDFFRQIKRHCAEPFTEYWTCIDYTGQQLFRHCRKQQAKFDECVLDKLGWVRPDLGELSKVTKVKTDRPLPENPYHSRPRPDPSPEIEGDLQPATHGSRFYFWTK

Target ORF information:

RefSeq Version	NM_014222.3
Organism	Homo sapiens(human)
Definition	Homo sapiens NADH:ubiquinone oxidoreductase subunit A8 (NDUFA8), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014222.3

ORF Insert Sequence:

ATGCCGGGGA TAGTGGAGCT GCCCACTCTA GAGGAGCTGA AAGTAGATGA GGTGAAAATT 
AGTTCTGCTG TGCTTAAAGC TGCGGCCCAT CACTATGGAG CTCAATGTGA TAAGCCCAAC 
AAGGAGTTTA TGCTCTGCCG CTGGGAAGAG AAAGATCCGA GGCGGTGTTT AGAGGAAGGC 
AAACTGGTCA ACAAGTGTGC TTTGGACTTC TTTAGGCAGA TAAAACGTCA CTGTGCAGAG 
CCTTTTACAG AATATTGGAC TTGCATTGAT TATACTGGCC AGCAGTTATT TCGTCACTGT 
CGCAAACAGC AGGCAAAGTT TGACGAGTGT GTGCTGGACA AACTGGGCTG GGTGCGGCCT 
GACCTGGGAG AACTGTCAAA GGTCACCAAA GTGAAAACAG ATCGACCTTT ACCGGAGAAT 
CCCTATCACT CAAGACCAAG ACCGGATCCC AGCCCTGAGA TCGAGGGAGA TCTGCAGCCT 
GCCACACATG GCAGCCGCTT TTATTTCTGG ACCAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NDUFA8 ( NM_001318195.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001305124.1 Homo sapiens NADH:ubiquinone oxidoreductase subunit A8 (NDUFA8), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu43297
Clone ID Related Accession (Same CDS sequence)	NM_001318195.1 , NM_001318195.2
Accession Version	NM_001318195.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 387bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-16
Organism	Homo sapiens(human)
Product	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BU602971.1, AK301520.1 and AL162423.18. On Dec 29, 2015 this sequence version replaced XM_005251998.2. Transcript Variant: This variant (2) contains an alternate 3' terminal exon, compared to variant 1. It encodes isoform 2 which is shorter and has a distinct C-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK301520.1, DC296576.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148874, SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END##

ATGCCGGGGA TAGTGGAGCT GCCCACTCTA GAGGAGCTGA AAGTAGATGA GGTGAAAATT 
AGTTCTGCTG TGCTTAAAGC TGCGGCCCAT CACTATGGAG CTCAATGTGA TAAGCCCAAC 
AAGGAGTTTA TGCTCTGCCG CTGGGAAGAG AAAGATCCGA GGCGGTGTTT AGAGGAAGGC 
AAACTGGTCA ACAAGTGTGC TTTGGACTTC TTTAGGCAGA TAAAACGTCA CTGTGCAGAG 
CCTTTTACAG AATATTGGAC TTGCATTGAT TATACTGGCC AGCAGTTATT TCGTCACTGT 
CGCAAACAGC AGGCAAAGTT TGACGAGTGT GTGCTGGACA AACTGGGCTG GGTGCGGCCT 
GACCTGGGAG AACTGTCAAA GGGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001305124.1
CDS	143..529
Translation	MPGIVELPTLEELKVDEVKISSAVLKAAAHHYGAQCDKPNKEFMLCRWEEKDPRRCLEEGKLVNKCALDFFRQIKRHCAEPFTEYWTCIDYTGQQLFRHCRKQQAKFDECVLDKLGWVRPDLGELSKG

Target ORF information:

RefSeq Version	NM_001318195.1
Organism	Homo sapiens(human)
Definition	Homo sapiens NADH:ubiquinone oxidoreductase subunit A8 (NDUFA8), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001318195.1

ORF Insert Sequence:

ATGCCGGGGA TAGTGGAGCT GCCCACTCTA GAGGAGCTGA AAGTAGATGA GGTGAAAATT 
AGTTCTGCTG TGCTTAAAGC TGCGGCCCAT CACTATGGAG CTCAATGTGA TAAGCCCAAC 
AAGGAGTTTA TGCTCTGCCG CTGGGAAGAG AAAGATCCGA GGCGGTGTTT AGAGGAAGGC 
AAACTGGTCA ACAAGTGTGC TTTGGACTTC TTTAGGCAGA TAAAACGTCA CTGTGCAGAG 
CCTTTTACAG AATATTGGAC TTGCATTGAT TATACTGGCC AGCAGTTATT TCGTCACTGT 
CGCAAACAGC AGGCAAAGTT TGACGAGTGT GTGCTGGACA AACTGGGCTG GGTGCGGCCT 
GACCTGGGAG AACTGTCAAA GGGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NDUFA8 ( NM_001318195.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001305124.1 Homo sapiens NADH:ubiquinone oxidoreductase subunit A8 (NDUFA8), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu43297
Clone ID Related Accession (Same CDS sequence)	NM_001318195.1 , NM_001318195.2
Accession Version	NM_001318195.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 387bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK301520.1 and AL162423.18. On May 31, 2019 this sequence version replaced NM_001318195.1. Transcript Variant: This variant (2) contains an alternate 3' terminal exon, compared to variant 1. It encodes isoform 2 which is shorter and has a distinct C-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK301520.1, DC296576.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148874, SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END##

ATGCCGGGGA TAGTGGAGCT GCCCACTCTA GAGGAGCTGA AAGTAGATGA GGTGAAAATT 
AGTTCTGCTG TGCTTAAAGC TGCGGCCCAT CACTATGGAG CTCAATGTGA TAAGCCCAAC 
AAGGAGTTTA TGCTCTGCCG CTGGGAAGAG AAAGATCCGA GGCGGTGTTT AGAGGAAGGC 
AAACTGGTCA ACAAGTGTGC TTTGGACTTC TTTAGGCAGA TAAAACGTCA CTGTGCAGAG 
CCTTTTACAG AATATTGGAC TTGCATTGAT TATACTGGCC AGCAGTTATT TCGTCACTGT 
CGCAAACAGC AGGCAAAGTT TGACGAGTGT GTGCTGGACA AACTGGGCTG GGTGCGGCCT 
GACCTGGGAG AACTGTCAAA GGGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001305124.1
CDS	103..489
Translation	MPGIVELPTLEELKVDEVKISSAVLKAAAHHYGAQCDKPNKEFMLCRWEEKDPRRCLEEGKLVNKCALDFFRQIKRHCAEPFTEYWTCIDYTGQQLFRHCRKQQAKFDECVLDKLGWVRPDLGELSKG

Target ORF information:

RefSeq Version	NM_001318195.2
Organism	Homo sapiens(human)
Definition	Homo sapiens NADH:ubiquinone oxidoreductase subunit A8 (NDUFA8), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001318195.2

ORF Insert Sequence:

ATGCCGGGGA TAGTGGAGCT GCCCACTCTA GAGGAGCTGA AAGTAGATGA GGTGAAAATT 
AGTTCTGCTG TGCTTAAAGC TGCGGCCCAT CACTATGGAG CTCAATGTGA TAAGCCCAAC 
AAGGAGTTTA TGCTCTGCCG CTGGGAAGAG AAAGATCCGA GGCGGTGTTT AGAGGAAGGC 
AAACTGGTCA ACAAGTGTGC TTTGGACTTC TTTAGGCAGA TAAAACGTCA CTGTGCAGAG 
CCTTTTACAG AATATTGGAC TTGCATTGAT TATACTGGCC AGCAGTTATT TCGTCACTGT 
CGCAAACAGC AGGCAAAGTT TGACGAGTGT GTGCTGGACA AACTGGGCTG GGTGCGGCCT 
GACCTGGGAG AACTGTCAAA GGGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NDUFA8 ( NM_014222.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_055037.1 Homo sapiens NADH:ubiquinone oxidoreductase subunit A8 (NDUFA8), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu55765
Clone ID Related Accession (Same CDS sequence)	NM_014222.2 , NM_014222.3
Accession Version	NM_014222.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 519bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Homo sapiens(human)
Product	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BU602971.1, AK314135.1 and BC001016.2. This sequence is a reference standard in the RefSeqGene project. On Aug 8, 2003 this sequence version replaced NM_014222.1. Transcript Variant: This variant (1) represents the shorter transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.542641.1, SRR1163658.272283.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCCGGGGA TAGTGGAGCT GCCCACTCTA GAGGAGCTGA AAGTAGATGA GGTGAAAATT 
AGTTCTGCTG TGCTTAAAGC TGCGGCCCAT CACTATGGAG CTCAATGTGA TAAGCCCAAC 
AAGGAGTTTA TGCTCTGCCG CTGGGAAGAG AAAGATCCGA GGCGGTGTTT AGAGGAAGGC 
AAACTGGTCA ACAAGTGTGC TTTGGACTTC TTTAGGCAGA TAAAACGTCA CTGTGCAGAG 
CCTTTTACAG AATATTGGAC TTGCATTGAT TATACTGGCC AGCAGTTATT TCGTCACTGT 
CGCAAACAGC AGGCAAAGTT TGACGAGTGT GTGCTGGACA AACTGGGCTG GGTGCGGCCT 
GACCTGGGAG AACTGTCAAA GGTCACCAAA GTGAAAACAG ATCGACCTTT ACCGGAGAAT 
CCCTATCACT CAAGACCAAG ACCGGATCCC AGCCCTGAGA TCGAGGGAGA TCTGCAGCCT 
GCCACACATG GCAGCCGCTT TTATTTCTGG ACCAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055037.1
CDS	143..661
Translation	MPGIVELPTLEELKVDEVKISSAVLKAAAHHYGAQCDKPNKEFMLCRWEEKDPRRCLEEGKLVNKCALDFFRQIKRHCAEPFTEYWTCIDYTGQQLFRHCRKQQAKFDECVLDKLGWVRPDLGELSKVTKVKTDRPLPENPYHSRPRPDPSPEIEGDLQPATHGSRFYFWTK

Target ORF information:

RefSeq Version	NM_014222.2
Organism	Homo sapiens(human)
Definition	Homo sapiens NADH:ubiquinone oxidoreductase subunit A8 (NDUFA8), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014222.2

ORF Insert Sequence:

ATGCCGGGGA TAGTGGAGCT GCCCACTCTA GAGGAGCTGA AAGTAGATGA GGTGAAAATT 
AGTTCTGCTG TGCTTAAAGC TGCGGCCCAT CACTATGGAG CTCAATGTGA TAAGCCCAAC 
AAGGAGTTTA TGCTCTGCCG CTGGGAAGAG AAAGATCCGA GGCGGTGTTT AGAGGAAGGC 
AAACTGGTCA ACAAGTGTGC TTTGGACTTC TTTAGGCAGA TAAAACGTCA CTGTGCAGAG 
CCTTTTACAG AATATTGGAC TTGCATTGAT TATACTGGCC AGCAGTTATT TCGTCACTGT 
CGCAAACAGC AGGCAAAGTT TGACGAGTGT GTGCTGGACA AACTGGGCTG GGTGCGGCCT 
GACCTGGGAG AACTGTCAAA GGTCACCAAA GTGAAAACAG ATCGACCTTT ACCGGAGAAT 
CCCTATCACT CAAGACCAAG ACCGGATCCC AGCCCTGAGA TCGAGGGAGA TCTGCAGCCT 
GCCACACATG GCAGCCGCTT TTATTTCTGG ACCAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Accessory subunits are integral for assembly and function of human mitochondrial complex I.
Nature538(7623)123-126(2016 Oct)
Stroud DA,Surgenor EE,Formosa LE,Reljic B,Frazier AE,Dibley MG,Osellame LD,Stait T,Beilharz TH,Thorburn DR,Salim A,Ryan MT

Mitochondrial Protein Interaction Mapping Identifies Regulators of Respiratory Chain Function.
Molecular cell63(4)621-632(2016 Aug)
Floyd BJ,Wilkerson EM,Veling MT,Minogue CE,Xia C,Beebe ET,Wrobel RL,Cho H,Kremer LS,Alston CL,Gromek KA,Dolan BK,Ulbrich A,Stefely JA,Bohl SL,Werner KM,Jochem A,Westphall MS,Rensvold JW,Taylor RW,Prokisch H,Kim JP,Coon JJ,Pagliarini DJ

Protein import and oxidative folding in the mitochondrial intermembrane space of intact mammalian cells.
Molecular biology of the cell24(14)2160-70(2013 Jul)
Fischer M,Horn S,Belkacemi A,Kojer K,Petrungaro C,Habich M,Ali M,K?ttner V,Bien M,Kauff F,Dengjel J,Herrmann JM,Riemer J

KIF14 negatively regulates Rap1a-Radil signaling during breast cancer progression.
The Journal of cell biology199(6)951-67(2012 Dec)
Ahmed SM,Th?riault BL,Uppalapati M,Chiu CW,Gallie BL,Sidhu SS,Angers S

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
PloS one7(12)e51954(2012)
Comuzzie AG,Cole SA,Laston SL,Voruganti VS,Haack K,Gibbs RA,Butte NF

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

NDUFA8 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報