Gene Symbol | MRC1 |
Entrez Gene ID | 4360 |
Full Name | mannose receptor C-type 1 |
Synonyms | CD206,CLEC13D,CLEC13DL,MMR,MRC1L1,bA541I19.1,hMR |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Sep 2015]. |
Disorder MIM: |