MMP10 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MMP10
Entrez Gene ID	4319
Full Name	matrix metallopeptidase 10
Synonyms	SL-2,STMY2
General protein information	Preferred Names matrix metallopeptidase 10 Names stromelysin-2 MMP-10 matrix metalloprotease 10 matrix metalloproteinase 10 (stromelysin 2) matrix metalloproteinase-10 transin 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11q22.2
Summary	This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down fibronectin, laminin, elastin, proteoglycan core protein, gelatins, and several types of collagen. The gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016].
Disorder MIM:	185260

mRNA and Protein(s)

mRNA	Protein	Name
NM_002425.2	NP_002416.1	stromelysin-2 preproprotein
NM_002425.3	NP_002416.1	stromelysin-2 preproprotein

Pathways from BioSystems

Homologies

	MMP10	XP_001086245.1
Rattus norvegicus (Norway rat)	Mmp10	NP_598198.1
Mus musculus (house mouse)	Mmp10	NP_062344.1
Pan troglodytes (chimpanzee)	MMP10	XP_001153881.1
Homo sapiens (human)	MMP10	NP_002416.1
Gallus gallus (chicken)	MMP10	NP_001265018.1

Gene Ontology
Bibliography

Related articles in PubMed

Role of Stromelysin 2 (Matrix Metalloproteinase 10) as a Novel Mediator of Vascular Remodeling Underlying Pulmonary Hypertension Associated With Systemic Sclerosis.
Avouac J, Guignabert C, Hoffmann-Vold AM, Ruiz B, Dorfmuller P, Pezet S, Amar O, Tu L, Van Wassenhove J, Sadoine J, Launay D, Elhai M, Cauvet A, Subramaniam A, Resnick R, Hachulla E, Molberg ?, Kahan A, Humbert M, Allanore Y
Arthritis & rheumatology (Hoboken, N.J.)69(11)2209-2221(2017 11)

Genomic characterization of tobacco/nut chewing HPV-negative early stage tongue tumors identify MMP10 asa candidate to predict metastases.
Upadhyay P, Gardi N, Desai S, Chandrani P, Joshi A, Dharavath B, Arora P, Bal M, Nair S, Dutt A
Oral oncology7356-64(2017 Oct)

Novel genes and mutations in patients affected by recurrent pregnancy loss.
Quintero-Ronderos P, Mercier E, Fukuda M, Gonz?lez R, Su?rez CF, Patarroyo MA, Vaiman D, Gris JC, Laissue P
PloS one12(10)e0186149(2017)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

MMP10 is overexpressed in the serum and pulmonary arteries of patients with systemic sclerosis-associated pulmonary hypertension.
Title: Role of Stromelysin 2 (Matrix Metalloproteinase 10) as a Novel Mediator of Vascular Remodeling Underlying Pulmonary Hypertension Associated With Systemic Sclerosis.

MMP10 expression is significantly upregulated in human masticatory mucosa during wound healing.
Title: Human gingiva transcriptome during wound healing.

Mycobacterium tuberculosis activates inflammatory and stromal cells to secrete MMP-10, and this is partly driven by the virulence factor early secretory antigenic target-6.
Title: Early Secretory Antigenic Target-6 Drives Matrix Metalloproteinase-10 Gene Expression and Secretion in Tuberculosis.

We conclude that in the resected esophageal cancer an increased mRNA expression of MMP-7, MMP-10 and TIMP-1 correlated with clinicopathologic features. We suggest that these genes may play a role during progression of the disease MMP-10, MMP-7, TIMP-1, TIMP-2 were overexpressed in 73%, 85%, 55% and 42% of esophageal cancer samples, respectively.
Title: MMP-10, MMP-7, TIMP-1 and TIMP-2 mRNA expression in esophageal cancer.

Using a quantum chemical approach method, it has been established that mutations in MMP-10 and FGA proteins led to substantial energetic modifications suggesting an impact on their functions and/or stability in the recurrent pregnancy loss patients.
Title: Novel genes and mutations in patients affected by recurrent pregnancy loss.

The following MMP10 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MMP10 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu23759	NM_002425.3 Latest version!	Homo sapiens matrix metallopeptidase 10 (MMP10), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu23759	NM_002425.2	Homo sapiens matrix metallopeptidase 10 (MMP10), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MMP10 ( NM_002425.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_002416.1 Homo sapiens matrix metallopeptidase 10 (MMP10), mRNA.

Price & Availability↑

CloneID	OHu23759
Clone ID Related Accession (Same CDS sequence)	NM_002425.2 , NM_002425.3
Accession Version	NM_002425.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1431bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-31
Organism	Homo sapiens(human)
Product	stromelysin-2 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK313960.1 and BC002591.2. On May 15, 2010 this sequence version replaced NM_002425.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC002591.2, X07820.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATGCATC TTGCATTCCT TGTGCTGTTG TGTCTGCCAG TCTGCTCTGC CTATCCTCTG 
AGTGGGGCAG CAAAAGAGGA GGACTCCAAC AAGGATCTTG CCCAGCAATA CCTAGAAAAG 
TACTACAACC TCGAAAAGGA TGTGAAACAG TTTAGAAGAA AGGACAGTAA TCTCATTGTT 
AAAAAAATCC AAGGAATGCA GAAGTTCCTT GGGTTGGAGG TGACAGGGAA GCTAGACACT 
GACACTCTGG AGGTGATGCG CAAGCCCAGG TGTGGAGTTC CTGACGTTGG TCACTTCAGC 
TCCTTTCCTG GCATGCCGAA GTGGAGGAAA ACCCACCTTA CATACAGGAT TGTGAATTAT 
ACACCAGATT TGCCAAGAGA TGCTGTTGAT TCTGCCATTG AGAAAGCTCT GAAAGTCTGG 
GAAGAGGTGA CTCCACTCAC ATTCTCCAGG CTGTATGAAG GAGAGGCTGA TATAATGATC 
TCTTTTGCAG TTAAAGAACA TGGAGACTTT TACTCTTTTG ATGGCCCAGG ACACAGTTTG 
GCTCATGCCT ACCCACCTGG ACCTGGGCTT TATGGAGATA TTCACTTTGA TGATGATGAA 
AAATGGACAG AAGATGCATC AGGCACCAAT TTATTCCTCG TTGCTGCTCA TGAACTTGGC 
CACTCCCTGG GGCTCTTTCA CTCAGCCAAC ACTGAAGCTT TGATGTACCC ACTCTACAAC 
TCATTCACAG AGCTCGCCCA GTTCCGCCTT TCGCAAGATG ATGTGAATGG CATTCAGTCT 
CTCTACGGAC CTCCCCCTGC CTCTACTGAG GAACCCCTGG TGCCCACAAA ATCTGTTCCT 
TCGGGATCTG AGATGCCAGC CAAGTGTGAT CCTGCTTTGT CCTTCGATGC CATCAGCACT 
CTGAGGGGAG AATATCTGTT CTTTAAAGAC AGATATTTTT GGCGAAGATC CCACTGGAAC 
CCTGAACCTG AATTTCATTT GATTTCTGCA TTTTGGCCCT CTCTTCCATC ATATTTGGAT 
GCTGCATATG AAGTTAACAG CAGGGACACC GTTTTTATTT TTAAAGGAAA TGAGTTCTGG 
GCCATCAGAG GAAATGAGGT ACAAGCAGGT TATCCAAGAG GCATCCATAC CCTGGGTTTT 
CCTCCAACCA TAAGGAAAAT TGATGCAGCT GTTTCTGACA AGGAAAAGAA GAAAACATAC 
TTCTTTGCAG CGGACAAATA CTGGAGATTT GATGAAAATA GCCAGTCCAT GGAGCAAGGC 
TTCCCTAGAC TAATAGCTGA TGACTTTCCA GGAGTTGAGC CTAAGGTTGA TGCTGTATTA 
CAGGCATTTG GATTTTTCTA CTTCTTCAGT GGATCATCAC AGTTTGAGTT TGACCCCAAT 
GCCAGGATGG TGACACACAT ATTAAAGAGT AACAGCTGGT TACATTGCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002416.1
CDS	38..1468
Translation	MMHLAFLVLLCLPVCSAYPLSGAAKEEDSNKDLAQQYLEKYYNLEKDVKQFRRKDSNLIVKKIQGMQKFLGLEVTGKLDTDTLEVMRKPRCGVPDVGHFSSFPGMPKWRKTHLTYRIVNYTPDLPRDAVDSAIEKALKVWEEVTPLTFSRLYEGEADIMISFAVKEHGDFYSFDGPGHSLAHAYPPGPGLYGDIHFDDDEKWTEDASGTNLFLVAAHELGHSLGLFHSANTEALMYPLYNSFTELAQFRLSQDDVNGIQSLYGPPPASTEEPLVPTKSVPSGSEMPAKCDPALSFDAISTLRGEYLFFKDRYFWRRSHWNPEPEFHLISAFWPSLPSYLDAAYEVNSRDTVFIFKGNEFWAIRGNEVQAGYPRGIHTLGFPPTIRKIDAAVSDKEKKKTYFFAADKYWRFDENSQSMEQGFPRLIADDFPGVEPKVDAVLQAFGFFYFFSGSSQFEFDPNARMVTHILKSNSWLHC

Target ORF information:

RefSeq Version	NM_002425.2
Organism	Homo sapiens(human)
Definition	Homo sapiens matrix metallopeptidase 10 (MMP10), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002425.2

ORF Insert Sequence:

ATGATGCATC TTGCATTCCT TGTGCTGTTG TGTCTGCCAG TCTGCTCTGC CTATCCTCTG 
AGTGGGGCAG CAAAAGAGGA GGACTCCAAC AAGGATCTTG CCCAGCAATA CCTAGAAAAG 
TACTACAACC TCGAAAAGGA TGTGAAACAG TTTAGAAGAA AGGACAGTAA TCTCATTGTT 
AAAAAAATCC AAGGAATGCA GAAGTTCCTT GGGTTGGAGG TGACAGGGAA GCTAGACACT 
GACACTCTGG AGGTGATGCG CAAGCCCAGG TGTGGAGTTC CTGACGTTGG TCACTTCAGC 
TCCTTTCCTG GCATGCCGAA GTGGAGGAAA ACCCACCTTA CATACAGGAT TGTGAATTAT 
ACACCAGATT TGCCAAGAGA TGCTGTTGAT TCTGCCATTG AGAAAGCTCT GAAAGTCTGG 
GAAGAGGTGA CTCCACTCAC ATTCTCCAGG CTGTATGAAG GAGAGGCTGA TATAATGATC 
TCTTTTGCAG TTAAAGAACA TGGAGACTTT TACTCTTTTG ATGGCCCAGG ACACAGTTTG 
GCTCATGCCT ACCCACCTGG ACCTGGGCTT TATGGAGATA TTCACTTTGA TGATGATGAA 
AAATGGACAG AAGATGCATC AGGCACCAAT TTATTCCTCG TTGCTGCTCA TGAACTTGGC 
CACTCCCTGG GGCTCTTTCA CTCAGCCAAC ACTGAAGCTT TGATGTACCC ACTCTACAAC 
TCATTCACAG AGCTCGCCCA GTTCCGCCTT TCGCAAGATG ATGTGAATGG CATTCAGTCT 
CTCTACGGAC CTCCCCCTGC CTCTACTGAG GAACCCCTGG TGCCCACAAA ATCTGTTCCT 
TCGGGATCTG AGATGCCAGC CAAGTGTGAT CCTGCTTTGT CCTTCGATGC CATCAGCACT 
CTGAGGGGAG AATATCTGTT CTTTAAAGAC AGATATTTTT GGCGAAGATC CCACTGGAAC 
CCTGAACCTG AATTTCATTT GATTTCTGCA TTTTGGCCCT CTCTTCCATC ATATTTGGAT 
GCTGCATATG AAGTTAACAG CAGGGACACC GTTTTTATTT TTAAAGGAAA TGAGTTCTGG 
GCCATCAGAG GAAATGAGGT ACAAGCAGGT TATCCAAGAG GCATCCATAC CCTGGGTTTT 
CCTCCAACCA TAAGGAAAAT TGATGCAGCT GTTTCTGACA AGGAAAAGAA GAAAACATAC 
TTCTTTGCAG CGGACAAATA CTGGAGATTT GATGAAAATA GCCAGTCCAT GGAGCAAGGC 
TTCCCTAGAC TAATAGCTGA TGACTTTCCA GGAGTTGAGC CTAAGGTTGA TGCTGTATTA 
CAGGCATTTG GATTTTTCTA CTTCTTCAGT GGATCATCAC AGTTTGAGTT TGACCCCAAT 
GCCAGGATGG TGACACACAT ATTAAAGAGT AACAGCTGGT TACATTGCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MMP10 ( NM_002425.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002416.1 Homo sapiens matrix metallopeptidase 10 (MMP10), mRNA.

Price & Availability↑

CloneID	OHu23759
Clone ID Related Accession (Same CDS sequence)	NM_002425.2 , NM_002425.3
Accession Version	NM_002425.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1431bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Homo sapiens(human)
Product	stromelysin-2 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK313960.1 and BC002591.2. On Nov 22, 2018 this sequence version replaced NM_002425.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK222601.1, SRR5189667.372209.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1966682, SAMEA1968189 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000279441.9/ ENSP00000279441.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGATGCATC TTGCATTCCT TGTGCTGTTG TGTCTGCCAG TCTGCTCTGC CTATCCTCTG 
AGTGGGGCAG CAAAAGAGGA GGACTCCAAC AAGGATCTTG CCCAGCAATA CCTAGAAAAG 
TACTACAACC TCGAAAAGGA TGTGAAACAG TTTAGAAGAA AGGACAGTAA TCTCATTGTT 
AAAAAAATCC AAGGAATGCA GAAGTTCCTT GGGTTGGAGG TGACAGGGAA GCTAGACACT 
GACACTCTGG AGGTGATGCG CAAGCCCAGG TGTGGAGTTC CTGACGTTGG TCACTTCAGC 
TCCTTTCCTG GCATGCCGAA GTGGAGGAAA ACCCACCTTA CATACAGGAT TGTGAATTAT 
ACACCAGATT TGCCAAGAGA TGCTGTTGAT TCTGCCATTG AGAAAGCTCT GAAAGTCTGG 
GAAGAGGTGA CTCCACTCAC ATTCTCCAGG CTGTATGAAG GAGAGGCTGA TATAATGATC 
TCTTTTGCAG TTAAAGAACA TGGAGACTTT TACTCTTTTG ATGGCCCAGG ACACAGTTTG 
GCTCATGCCT ACCCACCTGG ACCTGGGCTT TATGGAGATA TTCACTTTGA TGATGATGAA 
AAATGGACAG AAGATGCATC AGGCACCAAT TTATTCCTCG TTGCTGCTCA TGAACTTGGC 
CACTCCCTGG GGCTCTTTCA CTCAGCCAAC ACTGAAGCTT TGATGTACCC ACTCTACAAC 
TCATTCACAG AGCTCGCCCA GTTCCGCCTT TCGCAAGATG ATGTGAATGG CATTCAGTCT 
CTCTACGGAC CTCCCCCTGC CTCTACTGAG GAACCCCTGG TGCCCACAAA ATCTGTTCCT 
TCGGGATCTG AGATGCCAGC CAAGTGTGAT CCTGCTTTGT CCTTCGATGC CATCAGCACT 
CTGAGGGGAG AATATCTGTT CTTTAAAGAC AGATATTTTT GGCGAAGATC CCACTGGAAC 
CCTGAACCTG AATTTCATTT GATTTCTGCA TTTTGGCCCT CTCTTCCATC ATATTTGGAT 
GCTGCATATG AAGTTAACAG CAGGGACACC GTTTTTATTT TTAAAGGAAA TGAGTTCTGG 
GCCATCAGAG GAAATGAGGT ACAAGCAGGT TATCCAAGAG GCATCCATAC CCTGGGTTTT 
CCTCCAACCA TAAGGAAAAT TGATGCAGCT GTTTCTGACA AGGAAAAGAA GAAAACATAC 
TTCTTTGCAG CGGACAAATA CTGGAGATTT GATGAAAATA GCCAGTCCAT GGAGCAAGGC 
TTCCCTAGAC TAATAGCTGA TGACTTTCCA GGAGTTGAGC CTAAGGTTGA TGCTGTATTA 
CAGGCATTTG GATTTTTCTA CTTCTTCAGT GGATCATCAC AGTTTGAGTT TGACCCCAAT 
GCCAGGATGG TGACACACAT ATTAAAGAGT AACAGCTGGT TACATTGCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002416.1
CDS	38..1468
Translation	MMHLAFLVLLCLPVCSAYPLSGAAKEEDSNKDLAQQYLEKYYNLEKDVKQFRRKDSNLIVKKIQGMQKFLGLEVTGKLDTDTLEVMRKPRCGVPDVGHFSSFPGMPKWRKTHLTYRIVNYTPDLPRDAVDSAIEKALKVWEEVTPLTFSRLYEGEADIMISFAVKEHGDFYSFDGPGHSLAHAYPPGPGLYGDIHFDDDEKWTEDASGTNLFLVAAHELGHSLGLFHSANTEALMYPLYNSFTELAQFRLSQDDVNGIQSLYGPPPASTEEPLVPTKSVPSGSEMPAKCDPALSFDAISTLRGEYLFFKDRYFWRRSHWNPEPEFHLISAFWPSLPSYLDAAYEVNSRDTVFIFKGNEFWAIRGNEVQAGYPRGIHTLGFPPTIRKIDAAVSDKEKKKTYFFAADKYWRFDENSQSMEQGFPRLIADDFPGVEPKVDAVLQAFGFFYFFSGSSQFEFDPNARMVTHILKSNSWLHC

Target ORF information:

RefSeq Version	NM_002425.3
Organism	Homo sapiens(human)
Definition	Homo sapiens matrix metallopeptidase 10 (MMP10), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002425.3

ORF Insert Sequence:

ATGATGCATC TTGCATTCCT TGTGCTGTTG TGTCTGCCAG TCTGCTCTGC CTATCCTCTG 
AGTGGGGCAG CAAAAGAGGA GGACTCCAAC AAGGATCTTG CCCAGCAATA CCTAGAAAAG 
TACTACAACC TCGAAAAGGA TGTGAAACAG TTTAGAAGAA AGGACAGTAA TCTCATTGTT 
AAAAAAATCC AAGGAATGCA GAAGTTCCTT GGGTTGGAGG TGACAGGGAA GCTAGACACT 
GACACTCTGG AGGTGATGCG CAAGCCCAGG TGTGGAGTTC CTGACGTTGG TCACTTCAGC 
TCCTTTCCTG GCATGCCGAA GTGGAGGAAA ACCCACCTTA CATACAGGAT TGTGAATTAT 
ACACCAGATT TGCCAAGAGA TGCTGTTGAT TCTGCCATTG AGAAAGCTCT GAAAGTCTGG 
GAAGAGGTGA CTCCACTCAC ATTCTCCAGG CTGTATGAAG GAGAGGCTGA TATAATGATC 
TCTTTTGCAG TTAAAGAACA TGGAGACTTT TACTCTTTTG ATGGCCCAGG ACACAGTTTG 
GCTCATGCCT ACCCACCTGG ACCTGGGCTT TATGGAGATA TTCACTTTGA TGATGATGAA 
AAATGGACAG AAGATGCATC AGGCACCAAT TTATTCCTCG TTGCTGCTCA TGAACTTGGC 
CACTCCCTGG GGCTCTTTCA CTCAGCCAAC ACTGAAGCTT TGATGTACCC ACTCTACAAC 
TCATTCACAG AGCTCGCCCA GTTCCGCCTT TCGCAAGATG ATGTGAATGG CATTCAGTCT 
CTCTACGGAC CTCCCCCTGC CTCTACTGAG GAACCCCTGG TGCCCACAAA ATCTGTTCCT 
TCGGGATCTG AGATGCCAGC CAAGTGTGAT CCTGCTTTGT CCTTCGATGC CATCAGCACT 
CTGAGGGGAG AATATCTGTT CTTTAAAGAC AGATATTTTT GGCGAAGATC CCACTGGAAC 
CCTGAACCTG AATTTCATTT GATTTCTGCA TTTTGGCCCT CTCTTCCATC ATATTTGGAT 
GCTGCATATG AAGTTAACAG CAGGGACACC GTTTTTATTT TTAAAGGAAA TGAGTTCTGG 
GCCATCAGAG GAAATGAGGT ACAAGCAGGT TATCCAAGAG GCATCCATAC CCTGGGTTTT 
CCTCCAACCA TAAGGAAAAT TGATGCAGCT GTTTCTGACA AGGAAAAGAA GAAAACATAC 
TTCTTTGCAG CGGACAAATA CTGGAGATTT GATGAAAATA GCCAGTCCAT GGAGCAAGGC 
TTCCCTAGAC TAATAGCTGA TGACTTTCCA GGAGTTGAGC CTAAGGTTGA TGCTGTATTA 
CAGGCATTTG GATTTTTCTA CTTCTTCAGT GGATCATCAC AGTTTGAGTT TGACCCCAAT 
GCCAGGATGG TGACACACAT ATTAAAGAGT AACAGCTGGT TACATTGCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Role of Stromelysin 2 (Matrix Metalloproteinase 10) as a Novel Mediator of Vascular Remodeling Underlying Pulmonary Hypertension Associated With Systemic Sclerosis.
Arthritis & rheumatology (Hoboken, N.J.)69(11)2209-2221(2017 11)
Avouac J,Guignabert C,Hoffmann-Vold AM,Ruiz B,Dorfmuller P,Pezet S,Amar O,Tu L,Van Wassenhove J,Sadoine J,Launay D,Elhai M,Cauvet A,Subramaniam A,Resnick R,Hachulla E,Molberg ?,Kahan A,Humbert M,Allanore Y

Genomic characterization of tobacco/nut chewing HPV-negative early stage tongue tumors identify MMP10 asa candidate to predict metastases.
Oral oncology7356-64(2017 Oct)
Upadhyay P,Gardi N,Desai S,Chandrani P,Joshi A,Dharavath B,Arora P,Bal M,Nair S,Dutt A

Novel genes and mutations in patients affected by recurrent pregnancy loss.
PloS one12(10)e0186149(2017)
Quintero-Ronderos P,Mercier E,Fukuda M,Gonz?lez R,Su?rez CF,Patarroyo MA,Vaiman D,Gris JC,Laissue P

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MMP10 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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