MLLT3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MLLT3
Entrez Gene ID	4300
Full Name	MLLT3, super elongation complex subunit
Synonyms	AF9,YEATS3
General protein information	Preferred Names MLLT3, super elongation complex subunit Names protein AF-9 ALL1-fused gene from chromosome 9 protein YEATS domain-containing protein 3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); translocated to, 3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein myeloid/lymphoid or mixed-lineage leukemia; translocated to 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 9 Map Location: 9p21.3
Disorder MIM:	159558

mRNA and Protein(s)

mRNA	Protein	Name
XM_017014726.2	XP_016870215.1	protein AF-9 isoform X1
NM_004529.3	NP_004520.2	protein AF-9 isoform a
NM_001286691.2	NP_001273620.1	protein AF-9 isoform b
XM_017014726.1	XP_016870215.1	protein AF-9 isoform X1
NM_001286691.1	NP_001273620.1	protein AF-9 isoform b
XM_017014727.1	XP_016870216.1	protein AF-9 isoform X2
NM_004529.4	NP_004520.2	protein AF-9 isoform a

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	LOC549668	NP_001016914.1
Canis lupus familiaris (dog)	MLLT3	XP_538677.2
Bos taurus (cattle)	MLLT3	NP_001179478.1
	MLLT3	XP_001108646.2
Pan troglodytes (chimpanzee)	MLLT3	XP_001148491.1
Gallus gallus (chicken)	MLLT3	XP_424818.4
Homo sapiens (human)	MLLT3	NP_004520.2
Mus musculus (house mouse)	Mllt3	NP_081602.3

Gene Ontology
Bibliography

Related articles in PubMed

miR-564 inhibited metastasis and proliferation of prostate cancer by targeting MLLT3.
Meng FJ, Meng FM, Wu HX, Cao XF
European review for medical and pharmacological sciences21(21)4828-4834(2017 Nov)

MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in 11q23 acute myeloid leukemia.
Prange KHM, Mandoli A, Kuznetsova T, Wang SY, Sotoca AM, Marneth AE, van der Reijden BA, Stunnenberg HG, Martens JHA
Oncogene36(23)3346-3356(2017 Jun)

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

Structural Insights into Histone Crotonyl-Lysine Recognition by the AF9 YEATS Domain.
Zhang Q, Zeng L, Zhao C, Ju Y, Konuma T, Zhou MM
Structure (London, England : 1993)24(9)1606-12(2016 09)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

MLL-AF9 fusion is associated with acute myeloid leukemia.
Title: MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in 11q23 acute myeloid leukemia.

Exploring the mechanism how AF9 recognizes and binds H3K9ac by molecular dynamics simulations and free energy calculations.
Title: Exploring the mechanism how AF9 recognizes and binds H3K9ac by molecular dynamics simulations and free energy calculations.

Structural insights into H3 histone crotonyl-lysine recognition by the AF9 YEATS domain have been presented.
Title: Structural Insights into Histone Crotonyl-Lysine Recognition by the AF9 YEATS Domain.

Results show that human MLL-AF9 expression in mouse long-term hematopoietic stem cells causes invasive, chemoresistant acute myeloid leukemia that expresses genes related to epithelial-mesenchymal transition.
Title: MLL-AF9 Expression in Hematopoietic Stem Cells Drives a Highly Invasive AML Expressing EMT-Related Genes Linked to Poor Outcome.

Results show that MLL-AF9 reduces Id2 and increases E2-2 expression to drive and sustain leukemia stem cell potential in MLL-rearranged acute myeloid leukemia (AML). Low expression of Id2 or of an Id2 gene signature is associated with poor prognosis in not only MLL-rearranged but also t(8;21) AML patients.
Title: Id2 and E Proteins Orchestrate the Initiation and Maintenance of MLL-Rearranged Acute Myeloid Leukemia.

The following MLLT3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MLLT3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu12041	NM_004529.4 Latest version!	Homo sapiens MLLT3 super elongation complex subunit (MLLT3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu10641	NM_001286691.2 Latest version!	Homo sapiens MLLT3 super elongation complex subunit (MLLT3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
OHu98654	XM_017014726.2 Latest version!	Homo sapiens MLLT3 super elongation complex subunit (MLLT3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
OHu98655	XM_017014727.1 Latest version!	Homo sapiens MLLT3 super elongation complex subunit (MLLT3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
View Old Accession Versions >>
OHu98654	XM_017014726.1	Homo sapiens myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3 (MLLT3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
OHu10641	NM_001286691.1	Homo sapiens MLLT3 super elongation complex subunit (MLLT3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
OHu12041	NM_004529.3	Homo sapiens MLLT3, super elongation complex subunit (MLLT3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MLLT3 ( NM_004529.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_004520.2 Homo sapiens MLLT3, super elongation complex subunit (MLLT3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu12041
Clone ID Related Accession (Same CDS sequence)	NM_004529.3 , NM_004529.4
Accession Version	NM_004529.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1707bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-02
Organism	Homo sapiens(human)
Product	protein AF-9 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI550359.1, BC036089.1, L13744.1, AL512635.8 and AW451255.1. On Nov 14, 2013 this sequence version replaced NM_004529.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.40893.1, L13744.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTAGCT CGTGTGCCGT GCAGGTGAAG CTGGAGCTGG GGCACCGCGC CCAGGTGAGG 
AAAAAACCCA CCGTGGAGGG CTTCACCCAC GACTGGATGG TGTTCGTACG CGGTCCGGAG 
CACAGTAACA TACAGCACTT TGTGGAGAAA GTCGTCTTCC ACTTGCACGA AAGCTTTCCT 
AGGCCAAAAA GAGTGTGCAA AGATCCACCT TACAAAGTAG AAGAATCTGG GTATGCTGGT 
TTCATTTTGC CAATTGAAGT TTATTTTAAA AACAAGGAAG AACCTAGGAA AGTCCGCTTT 
GATTATGACT TATTCCTGCA TCTTGAAGGC CATCCACCAG TGAATCACCT CCGCTGTGAA 
AAGCTAACTT TCAACAACCC CACAGAGGAC TTTAGGAGAA AGTTGCTGAA GGCAGGAGGG 
GACCCTAATA GGAGTATTCA TACCAGCAGC AGCAGCAGCA GCAGCAGTAG CAGCAGCAGC 
AGCAGCAGCA GCAGCAGCAG TAGCAGCAGC AGCAGCAGCA GCAGCAGCAG CAGTAGCAGC 
AGCAGTAGCA GCAGCAGCAG CAGCAGTAGT ACCAGTTTTT CAAAGCCTCA CAAATTAATG 
AAGGAGCACA AGGAAAAACC TTCTAAAGAC TCCAGAGAAC ATAAAAGTGC CTTCAAAGAA 
CCTTCCAGGG ATCACAACAA ATCTTCCAAA GAATCCTCTA AGAAACCCAA AGAAAATAAA 
CCACTGAAAG AAGAGAAAAT AGTTCCTAAG ATGGCCTTCA AGGAACCTAA ACCCATGTCA 
AAAGAGCCAA AACCAGATAG TAACTTACTC ACCATCACCA GTGGACAAGA TAAGAAGGCT 
CCTAGTAAAA GGCCGCCCAT TTCAGATTCT GAAGAACTCT CAGCCAAAAA AAGGAAAAAG 
AGTAGCTCAG AGGCTTTATT TAAAAGTTTT TCTAGCGCAC CACCACTGAT ACTCACTTGT 
TCTGCTGACA AAAAACAGAT AAAAGATAAA TCTCATGTCA AGATGGGAAA GGTCAAAATT 
GAAAGTGAGA CATCAGAGAA GAAGAAATCA ACGTTACCGC CATTTGATGA TATTGTGGAT 
CCCAATGATT CAGATGTGGA GGAGAATATA TCCTCTAAAT CTGATTCTGA ACAACCCAGT 
CCTGCCAGCT CCAGCTCCAG CTCCAGCTCC AGCTTCACAC CATCCCAGAC CAGGCAACAA 
GGTCCTTTGA GGTCTATAAT GAAAGATCTG CATTCTGATG ACAATGAGGA GGAATCAGAT 
GAAGTGGAGG ATAACGACAA TGACTCTGAA ATGGAGAGGC CTGTAAATAG AGGAGGCAGC 
CGAAGTCGCA GAGTTAGCTT AAGTGATGGC AGCGATAGTG AAAGCAGTTC TGCTTCTTCA 
CCCCTACATC ACGAACCTCC ACCACCCTTA CTAAAAACCA ACAACAACCA GATTCTTGAA 
GTGAAAAGTC CAATAAAGCA AAGCAAATCA GATAAGCAAA TAAAGAATGG TGAATGTGAC 
AAGGCATACC TAGATGAACT GGTAGAGCTT CACAGAAGGT TAATGACATT GAGAGAAAGA 
CACATTCTGC AGCAGATCGT GAACCTTATA GAAGAAACTG GACACTTTCA TATCACAAAC 
ACAACATTTG ATTTTGATCT TTGCTCGCTG GACAAAACCA CAGTCCGTAA ACTACAGAGT 
TACCTGGAAA CATCTGGAAC ATCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004520.2
CDS	288..1994
Translation	MASSCAVQVKLELGHRAQVRKKPTVEGFTHDWMVFVRGPEHSNIQHFVEKVVFHLHESFPRPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEPRKVRFDYDLFLHLEGHPPVNHLRCEKLTFNNPTEDFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQILEVKSPIKQSKSDKQIKNGECDKAYLDELVELHRRLMTLRERHILQQIVNLIEETGHFHITNTTFDFDLCSLDKTTVRKLQSYLETSGTS

Target ORF information:

RefSeq Version	NM_004529.3
Organism	Homo sapiens(human)
Definition	Homo sapiens MLLT3, super elongation complex subunit (MLLT3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004529.3

ORF Insert Sequence:

ATGGCTAGCT CGTGTGCCGT GCAGGTGAAG CTGGAGCTGG GGCACCGCGC CCAGGTGAGG 
AAAAAACCCA CCGTGGAGGG CTTCACCCAC GACTGGATGG TGTTCGTACG CGGTCCGGAG 
CACAGTAACA TACAGCACTT TGTGGAGAAA GTCGTCTTCC ACTTGCACGA AAGCTTTCCT 
AGGCCAAAAA GAGTGTGCAA AGATCCACCT TACAAAGTAG AAGAATCTGG GTATGCTGGT 
TTCATTTTGC CAATTGAAGT TTATTTTAAA AACAAGGAAG AACCTAGGAA AGTCCGCTTT 
GATTATGACT TATTCCTGCA TCTTGAAGGC CATCCACCAG TGAATCACCT CCGCTGTGAA 
AAGCTAACTT TCAACAACCC CACAGAGGAC TTTAGGAGAA AGTTGCTGAA GGCAGGAGGG 
GACCCTAATA GGAGTATTCA TACCAGCAGC AGCAGCAGCA GCAGCAGTAG CAGCAGCAGC 
AGCAGCAGCA GCAGCAGCAG TAGCAGCAGC AGCAGCAGCA GCAGCAGCAG CAGTAGCAGC 
AGCAGTAGCA GCAGCAGCAG CAGCAGTAGT ACCAGTTTTT CAAAGCCTCA CAAATTAATG 
AAGGAGCACA AGGAAAAACC TTCTAAAGAC TCCAGAGAAC ATAAAAGTGC CTTCAAAGAA 
CCTTCCAGGG ATCACAACAA ATCTTCCAAA GAATCCTCTA AGAAACCCAA AGAAAATAAA 
CCACTGAAAG AAGAGAAAAT AGTTCCTAAG ATGGCCTTCA AGGAACCTAA ACCCATGTCA 
AAAGAGCCAA AACCAGATAG TAACTTACTC ACCATCACCA GTGGACAAGA TAAGAAGGCT 
CCTAGTAAAA GGCCGCCCAT TTCAGATTCT GAAGAACTCT CAGCCAAAAA AAGGAAAAAG 
AGTAGCTCAG AGGCTTTATT TAAAAGTTTT TCTAGCGCAC CACCACTGAT ACTCACTTGT 
TCTGCTGACA AAAAACAGAT AAAAGATAAA TCTCATGTCA AGATGGGAAA GGTCAAAATT 
GAAAGTGAGA CATCAGAGAA GAAGAAATCA ACGTTACCGC CATTTGATGA TATTGTGGAT 
CCCAATGATT CAGATGTGGA GGAGAATATA TCCTCTAAAT CTGATTCTGA ACAACCCAGT 
CCTGCCAGCT CCAGCTCCAG CTCCAGCTCC AGCTTCACAC CATCCCAGAC CAGGCAACAA 
GGTCCTTTGA GGTCTATAAT GAAAGATCTG CATTCTGATG ACAATGAGGA GGAATCAGAT 
GAAGTGGAGG ATAACGACAA TGACTCTGAA ATGGAGAGGC CTGTAAATAG AGGAGGCAGC 
CGAAGTCGCA GAGTTAGCTT AAGTGATGGC AGCGATAGTG AAAGCAGTTC TGCTTCTTCA 
CCCCTACATC ACGAACCTCC ACCACCCTTA CTAAAAACCA ACAACAACCA GATTCTTGAA 
GTGAAAAGTC CAATAAAGCA AAGCAAATCA GATAAGCAAA TAAAGAATGG TGAATGTGAC 
AAGGCATACC TAGATGAACT GGTAGAGCTT CACAGAAGGT TAATGACATT GAGAGAAAGA 
CACATTCTGC AGCAGATCGT GAACCTTATA GAAGAAACTG GACACTTTCA TATCACAAAC 
ACAACATTTG ATTTTGATCT TTGCTCGCTG GACAAAACCA CAGTCCGTAA ACTACAGAGT 
TACCTGGAAA CATCTGGAAC ATCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MLLT3 ( NM_004529.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_004520.2 Homo sapiens MLLT3 super elongation complex subunit (MLLT3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu12041
Clone ID Related Accession (Same CDS sequence)	NM_004529.3 , NM_004529.4
Accession Version	NM_004529.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1707bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	protein AF-9 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC036089.1, L13744.1 and AL512635.8. On Nov 23, 2018 this sequence version replaced NM_004529.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.86219.1, SRR1660803.40893.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000380338.9/ ENSP00000369695.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCTAGCT CGTGTGCCGT GCAGGTGAAG CTGGAGCTGG GGCACCGCGC CCAGGTGAGG 
AAAAAACCCA CCGTGGAGGG CTTCACCCAC GACTGGATGG TGTTCGTACG CGGTCCGGAG 
CACAGTAACA TACAGCACTT TGTGGAGAAA GTCGTCTTCC ACTTGCACGA AAGCTTTCCT 
AGGCCAAAAA GAGTGTGCAA AGATCCACCT TACAAAGTAG AAGAATCTGG GTATGCTGGT 
TTCATTTTGC CAATTGAAGT TTATTTTAAA AACAAGGAAG AACCTAGGAA AGTCCGCTTT 
GATTATGACT TATTCCTGCA TCTTGAAGGC CATCCACCAG TGAATCACCT CCGCTGTGAA 
AAGCTAACTT TCAACAACCC CACAGAGGAC TTTAGGAGAA AGTTGCTGAA GGCAGGAGGG 
GACCCTAATA GGAGTATTCA TACCAGCAGC AGCAGCAGCA GCAGCAGTAG CAGCAGCAGC 
AGCAGCAGCA GCAGCAGCAG TAGCAGCAGC AGCAGCAGCA GCAGCAGCAG CAGTAGCAGC 
AGCAGTAGCA GCAGCAGCAG CAGCAGTAGT ACCAGTTTTT CAAAGCCTCA CAAATTAATG 
AAGGAGCACA AGGAAAAACC TTCTAAAGAC TCCAGAGAAC ATAAAAGTGC CTTCAAAGAA 
CCTTCCAGGG ATCACAACAA ATCTTCCAAA GAATCCTCTA AGAAACCCAA AGAAAATAAA 
CCACTGAAAG AAGAGAAAAT AGTTCCTAAG ATGGCCTTCA AGGAACCTAA ACCCATGTCA 
AAAGAGCCAA AACCAGATAG TAACTTACTC ACCATCACCA GTGGACAAGA TAAGAAGGCT 
CCTAGTAAAA GGCCGCCCAT TTCAGATTCT GAAGAACTCT CAGCCAAAAA AAGGAAAAAG 
AGTAGCTCAG AGGCTTTATT TAAAAGTTTT TCTAGCGCAC CACCACTGAT ACTCACTTGT 
TCTGCTGACA AAAAACAGAT AAAAGATAAA TCTCATGTCA AGATGGGAAA GGTCAAAATT 
GAAAGTGAGA CATCAGAGAA GAAGAAATCA ACGTTACCGC CATTTGATGA TATTGTGGAT 
CCCAATGATT CAGATGTGGA GGAGAATATA TCCTCTAAAT CTGATTCTGA ACAACCCAGT 
CCTGCCAGCT CCAGCTCCAG CTCCAGCTCC AGCTTCACAC CATCCCAGAC CAGGCAACAA 
GGTCCTTTGA GGTCTATAAT GAAAGATCTG CATTCTGATG ACAATGAGGA GGAATCAGAT 
GAAGTGGAGG ATAACGACAA TGACTCTGAA ATGGAGAGGC CTGTAAATAG AGGAGGCAGC 
CGAAGTCGCA GAGTTAGCTT AAGTGATGGC AGCGATAGTG AAAGCAGTTC TGCTTCTTCA 
CCCCTACATC ACGAACCTCC ACCACCCTTA CTAAAAACCA ACAACAACCA GATTCTTGAA 
GTGAAAAGTC CAATAAAGCA AAGCAAATCA GATAAGCAAA TAAAGAATGG TGAATGTGAC 
AAGGCATACC TAGATGAACT GGTAGAGCTT CACAGAAGGT TAATGACATT GAGAGAAAGA 
CACATTCTGC AGCAGATCGT GAACCTTATA GAAGAAACTG GACACTTTCA TATCACAAAC 
ACAACATTTG ATTTTGATCT TTGCTCGCTG GACAAAACCA CAGTCCGTAA ACTACAGAGT 
TACCTGGAAA CATCTGGAAC ATCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004520.2
CDS	244..1950
Translation	MASSCAVQVKLELGHRAQVRKKPTVEGFTHDWMVFVRGPEHSNIQHFVEKVVFHLHESFPRPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEPRKVRFDYDLFLHLEGHPPVNHLRCEKLTFNNPTEDFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQILEVKSPIKQSKSDKQIKNGECDKAYLDELVELHRRLMTLRERHILQQIVNLIEETGHFHITNTTFDFDLCSLDKTTVRKLQSYLETSGTS

Target ORF information:

RefSeq Version	NM_004529.4
Organism	Homo sapiens(human)
Definition	Homo sapiens MLLT3 super elongation complex subunit (MLLT3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004529.4

ORF Insert Sequence:

ATGGCTAGCT CGTGTGCCGT GCAGGTGAAG CTGGAGCTGG GGCACCGCGC CCAGGTGAGG 
AAAAAACCCA CCGTGGAGGG CTTCACCCAC GACTGGATGG TGTTCGTACG CGGTCCGGAG 
CACAGTAACA TACAGCACTT TGTGGAGAAA GTCGTCTTCC ACTTGCACGA AAGCTTTCCT 
AGGCCAAAAA GAGTGTGCAA AGATCCACCT TACAAAGTAG AAGAATCTGG GTATGCTGGT 
TTCATTTTGC CAATTGAAGT TTATTTTAAA AACAAGGAAG AACCTAGGAA AGTCCGCTTT 
GATTATGACT TATTCCTGCA TCTTGAAGGC CATCCACCAG TGAATCACCT CCGCTGTGAA 
AAGCTAACTT TCAACAACCC CACAGAGGAC TTTAGGAGAA AGTTGCTGAA GGCAGGAGGG 
GACCCTAATA GGAGTATTCA TACCAGCAGC AGCAGCAGCA GCAGCAGTAG CAGCAGCAGC 
AGCAGCAGCA GCAGCAGCAG TAGCAGCAGC AGCAGCAGCA GCAGCAGCAG CAGTAGCAGC 
AGCAGTAGCA GCAGCAGCAG CAGCAGTAGT ACCAGTTTTT CAAAGCCTCA CAAATTAATG 
AAGGAGCACA AGGAAAAACC TTCTAAAGAC TCCAGAGAAC ATAAAAGTGC CTTCAAAGAA 
CCTTCCAGGG ATCACAACAA ATCTTCCAAA GAATCCTCTA AGAAACCCAA AGAAAATAAA 
CCACTGAAAG AAGAGAAAAT AGTTCCTAAG ATGGCCTTCA AGGAACCTAA ACCCATGTCA 
AAAGAGCCAA AACCAGATAG TAACTTACTC ACCATCACCA GTGGACAAGA TAAGAAGGCT 
CCTAGTAAAA GGCCGCCCAT TTCAGATTCT GAAGAACTCT CAGCCAAAAA AAGGAAAAAG 
AGTAGCTCAG AGGCTTTATT TAAAAGTTTT TCTAGCGCAC CACCACTGAT ACTCACTTGT 
TCTGCTGACA AAAAACAGAT AAAAGATAAA TCTCATGTCA AGATGGGAAA GGTCAAAATT 
GAAAGTGAGA CATCAGAGAA GAAGAAATCA ACGTTACCGC CATTTGATGA TATTGTGGAT 
CCCAATGATT CAGATGTGGA GGAGAATATA TCCTCTAAAT CTGATTCTGA ACAACCCAGT 
CCTGCCAGCT CCAGCTCCAG CTCCAGCTCC AGCTTCACAC CATCCCAGAC CAGGCAACAA 
GGTCCTTTGA GGTCTATAAT GAAAGATCTG CATTCTGATG ACAATGAGGA GGAATCAGAT 
GAAGTGGAGG ATAACGACAA TGACTCTGAA ATGGAGAGGC CTGTAAATAG AGGAGGCAGC 
CGAAGTCGCA GAGTTAGCTT AAGTGATGGC AGCGATAGTG AAAGCAGTTC TGCTTCTTCA 
CCCCTACATC ACGAACCTCC ACCACCCTTA CTAAAAACCA ACAACAACCA GATTCTTGAA 
GTGAAAAGTC CAATAAAGCA AAGCAAATCA GATAAGCAAA TAAAGAATGG TGAATGTGAC 
AAGGCATACC TAGATGAACT GGTAGAGCTT CACAGAAGGT TAATGACATT GAGAGAAAGA 
CACATTCTGC AGCAGATCGT GAACCTTATA GAAGAAACTG GACACTTTCA TATCACAAAC 
ACAACATTTG ATTTTGATCT TTGCTCGCTG GACAAAACCA CAGTCCGTAA ACTACAGAGT 
TACCTGGAAA CATCTGGAAC ATCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MLLT3 ( NM_001286691.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001273620.1 Homo sapiens MLLT3 super elongation complex subunit (MLLT3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu10641
Clone ID Related Accession (Same CDS sequence)	NM_001286691.2 , NM_001286691.1
Accession Version	NM_001286691.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1698bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	protein AF-9 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC306929.1, AK301474.1 and AL512635.8. On May 31, 2019 this sequence version replaced NM_001286691.1. Transcript Variant: This variant (2) uses an alternate 5' exon and it thus differs in the 5' UTR and 5' coding region, compared to variant 1. The encoded isoform (b) has a distinct N-terminus and is shorter than isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.165338.1, SRR3476690.889003.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTGTGCCG TGCAGGTGAA GCTGGAGCTG GGGCACCGCG CCCAGGTGAG GAAAAAACCC 
ACCGTGGAGG GCTTCACCCA CGACTGGATG GTGTTCGTAC GCGGTCCGGA GCACAGTAAC 
ATACAGCACT TTGTGGAGAA AGTCGTCTTC CACTTGCACG AAAGCTTTCC TAGGCCAAAA 
AGAGTGTGCA AAGATCCACC TTACAAAGTA GAAGAATCTG GGTATGCTGG TTTCATTTTG 
CCAATTGAAG TTTATTTTAA AAACAAGGAA GAACCTAGGA AAGTCCGCTT TGATTATGAC 
TTATTCCTGC ATCTTGAAGG CCATCCACCA GTGAATCACC TCCGCTGTGA AAAGCTAACT 
TTCAACAACC CCACAGAGGA CTTTAGGAGA AAGTTGCTGA AGGCAGGAGG GGACCCTAAT 
AGGAGTATTC ATACCAGCAG CAGCAGCAGC AGCAGCAGTA GCAGCAGCAG CAGCAGCAGC 
AGCAGCAGCA GTAGCAGCAG CAGCAGCAGC AGCAGCAGCA GCAGTAGCAG CAGCAGTAGC 
AGCAGCAGCA GCAGCAGTAG TACCAGTTTT TCAAAGCCTC ACAAATTAAT GAAGGAGCAC 
AAGGAAAAAC CTTCTAAAGA CTCCAGAGAA CATAAAAGTG CCTTCAAAGA ACCTTCCAGG 
GATCACAACA AATCTTCCAA AGAATCCTCT AAGAAACCCA AAGAAAATAA ACCACTGAAA 
GAAGAGAAAA TAGTTCCTAA GATGGCCTTC AAGGAACCTA AACCCATGTC AAAAGAGCCA 
AAACCAGATA GTAACTTACT CACCATCACC AGTGGACAAG ATAAGAAGGC TCCTAGTAAA 
AGGCCGCCCA TTTCAGATTC TGAAGAACTC TCAGCCAAAA AAAGGAAAAA GAGTAGCTCA 
GAGGCTTTAT TTAAAAGTTT TTCTAGCGCA CCACCACTGA TACTCACTTG TTCTGCTGAC 
AAAAAACAGA TAAAAGATAA ATCTCATGTC AAGATGGGAA AGGTCAAAAT TGAAAGTGAG 
ACATCAGAGA AGAAGAAATC AACGTTACCG CCATTTGATG ATATTGTGGA TCCCAATGAT 
TCAGATGTGG AGGAGAATAT ATCCTCTAAA TCTGATTCTG AACAACCCAG TCCTGCCAGC 
TCCAGCTCCA GCTCCAGCTC CAGCTTCACA CCATCCCAGA CCAGGCAACA AGGTCCTTTG 
AGGTCTATAA TGAAAGATCT GCATTCTGAT GACAATGAGG AGGAATCAGA TGAAGTGGAG 
GATAACGACA ATGACTCTGA AATGGAGAGG CCTGTAAATA GAGGAGGCAG CCGAAGTCGC 
AGAGTTAGCT TAAGTGATGG CAGCGATAGT GAAAGCAGTT CTGCTTCTTC ACCCCTACAT 
CACGAACCTC CACCACCCTT ACTAAAAACC AACAACAACC AGATTCTTGA AGTGAAAAGT 
CCAATAAAGC AAAGCAAATC AGATAAGCAA ATAAAGAATG GTGAATGTGA CAAGGCATAC 
CTAGATGAAC TGGTAGAGCT TCACAGAAGG TTAATGACAT TGAGAGAAAG ACACATTCTG 
CAGCAGATCG TGAACCTTAT AGAAGAAACT GGACACTTTC ATATCACAAA CACAACATTT 
GATTTTGATC TTTGCTCGCT GGACAAAACC ACAGTCCGTA AACTACAGAG TTACCTGGAA 
ACATCTGGAA CATCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001273620.1
CDS	164..1861
Translation	MCAVQVKLELGHRAQVRKKPTVEGFTHDWMVFVRGPEHSNIQHFVEKVVFHLHESFPRPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEPRKVRFDYDLFLHLEGHPPVNHLRCEKLTFNNPTEDFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQILEVKSPIKQSKSDKQIKNGECDKAYLDELVELHRRLMTLRERHILQQIVNLIEETGHFHITNTTFDFDLCSLDKTTVRKLQSYLETSGTS

Target ORF information:

RefSeq Version	NM_001286691.2
Organism	Homo sapiens(human)
Definition	Homo sapiens MLLT3 super elongation complex subunit (MLLT3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001286691.2

ORF Insert Sequence:

ATGTGTGCCG TGCAGGTGAA GCTGGAGCTG GGGCACCGCG CCCAGGTGAG GAAAAAACCC 
ACCGTGGAGG GCTTCACCCA CGACTGGATG GTGTTCGTAC GCGGTCCGGA GCACAGTAAC 
ATACAGCACT TTGTGGAGAA AGTCGTCTTC CACTTGCACG AAAGCTTTCC TAGGCCAAAA 
AGAGTGTGCA AAGATCCACC TTACAAAGTA GAAGAATCTG GGTATGCTGG TTTCATTTTG 
CCAATTGAAG TTTATTTTAA AAACAAGGAA GAACCTAGGA AAGTCCGCTT TGATTATGAC 
TTATTCCTGC ATCTTGAAGG CCATCCACCA GTGAATCACC TCCGCTGTGA AAAGCTAACT 
TTCAACAACC CCACAGAGGA CTTTAGGAGA AAGTTGCTGA AGGCAGGAGG GGACCCTAAT 
AGGAGTATTC ATACCAGCAG CAGCAGCAGC AGCAGCAGTA GCAGCAGCAG CAGCAGCAGC 
AGCAGCAGCA GTAGCAGCAG CAGCAGCAGC AGCAGCAGCA GCAGTAGCAG CAGCAGTAGC 
AGCAGCAGCA GCAGCAGTAG TACCAGTTTT TCAAAGCCTC ACAAATTAAT GAAGGAGCAC 
AAGGAAAAAC CTTCTAAAGA CTCCAGAGAA CATAAAAGTG CCTTCAAAGA ACCTTCCAGG 
GATCACAACA AATCTTCCAA AGAATCCTCT AAGAAACCCA AAGAAAATAA ACCACTGAAA 
GAAGAGAAAA TAGTTCCTAA GATGGCCTTC AAGGAACCTA AACCCATGTC AAAAGAGCCA 
AAACCAGATA GTAACTTACT CACCATCACC AGTGGACAAG ATAAGAAGGC TCCTAGTAAA 
AGGCCGCCCA TTTCAGATTC TGAAGAACTC TCAGCCAAAA AAAGGAAAAA GAGTAGCTCA 
GAGGCTTTAT TTAAAAGTTT TTCTAGCGCA CCACCACTGA TACTCACTTG TTCTGCTGAC 
AAAAAACAGA TAAAAGATAA ATCTCATGTC AAGATGGGAA AGGTCAAAAT TGAAAGTGAG 
ACATCAGAGA AGAAGAAATC AACGTTACCG CCATTTGATG ATATTGTGGA TCCCAATGAT 
TCAGATGTGG AGGAGAATAT ATCCTCTAAA TCTGATTCTG AACAACCCAG TCCTGCCAGC 
TCCAGCTCCA GCTCCAGCTC CAGCTTCACA CCATCCCAGA CCAGGCAACA AGGTCCTTTG 
AGGTCTATAA TGAAAGATCT GCATTCTGAT GACAATGAGG AGGAATCAGA TGAAGTGGAG 
GATAACGACA ATGACTCTGA AATGGAGAGG CCTGTAAATA GAGGAGGCAG CCGAAGTCGC 
AGAGTTAGCT TAAGTGATGG CAGCGATAGT GAAAGCAGTT CTGCTTCTTC ACCCCTACAT 
CACGAACCTC CACCACCCTT ACTAAAAACC AACAACAACC AGATTCTTGA AGTGAAAAGT 
CCAATAAAGC AAAGCAAATC AGATAAGCAA ATAAAGAATG GTGAATGTGA CAAGGCATAC 
CTAGATGAAC TGGTAGAGCT TCACAGAAGG TTAATGACAT TGAGAGAAAG ACACATTCTG 
CAGCAGATCG TGAACCTTAT AGAAGAAACT GGACACTTTC ATATCACAAA CACAACATTT 
GATTTTGATC TTTGCTCGCT GGACAAAACC ACAGTCCGTA AACTACAGAG TTACCTGGAA 
ACATCTGGAA CATCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MLLT3 ( NM_001286691.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001273620.1 Homo sapiens MLLT3 super elongation complex subunit (MLLT3), transcript variant 2, mRNA.

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CloneID	OHu10641
Clone ID Related Accession (Same CDS sequence)	NM_001286691.2 , NM_001286691.1
Accession Version	NM_001286691.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1698bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-03
Organism	Homo sapiens(human)
Product	protein AF-9 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC345433.1, DC306929.1, AK301474.1, AL512635.8 and AW451255.1. On Nov 14, 2013 this sequence version replaced XM_005251460.1. Transcript Variant: This variant (2) uses an alternate 5' exon and it thus differs in the 5' UTR and 5' coding region, compared to variant 1. The encoded isoform (b) has a distinct N-terminus and is shorter than isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.165338.1, AK301474.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTGTGCCG TGCAGGTGAA GCTGGAGCTG GGGCACCGCG CCCAGGTGAG GAAAAAACCC 
ACCGTGGAGG GCTTCACCCA CGACTGGATG GTGTTCGTAC GCGGTCCGGA GCACAGTAAC 
ATACAGCACT TTGTGGAGAA AGTCGTCTTC CACTTGCACG AAAGCTTTCC TAGGCCAAAA 
AGAGTGTGCA AAGATCCACC TTACAAAGTA GAAGAATCTG GGTATGCTGG TTTCATTTTG 
CCAATTGAAG TTTATTTTAA AAACAAGGAA GAACCTAGGA AAGTCCGCTT TGATTATGAC 
TTATTCCTGC ATCTTGAAGG CCATCCACCA GTGAATCACC TCCGCTGTGA AAAGCTAACT 
TTCAACAACC CCACAGAGGA CTTTAGGAGA AAGTTGCTGA AGGCAGGAGG GGACCCTAAT 
AGGAGTATTC ATACCAGCAG CAGCAGCAGC AGCAGCAGTA GCAGCAGCAG CAGCAGCAGC 
AGCAGCAGCA GTAGCAGCAG CAGCAGCAGC AGCAGCAGCA GCAGTAGCAG CAGCAGTAGC 
AGCAGCAGCA GCAGCAGTAG TACCAGTTTT TCAAAGCCTC ACAAATTAAT GAAGGAGCAC 
AAGGAAAAAC CTTCTAAAGA CTCCAGAGAA CATAAAAGTG CCTTCAAAGA ACCTTCCAGG 
GATCACAACA AATCTTCCAA AGAATCCTCT AAGAAACCCA AAGAAAATAA ACCACTGAAA 
GAAGAGAAAA TAGTTCCTAA GATGGCCTTC AAGGAACCTA AACCCATGTC AAAAGAGCCA 
AAACCAGATA GTAACTTACT CACCATCACC AGTGGACAAG ATAAGAAGGC TCCTAGTAAA 
AGGCCGCCCA TTTCAGATTC TGAAGAACTC TCAGCCAAAA AAAGGAAAAA GAGTAGCTCA 
GAGGCTTTAT TTAAAAGTTT TTCTAGCGCA CCACCACTGA TACTCACTTG TTCTGCTGAC 
AAAAAACAGA TAAAAGATAA ATCTCATGTC AAGATGGGAA AGGTCAAAAT TGAAAGTGAG 
ACATCAGAGA AGAAGAAATC AACGTTACCG CCATTTGATG ATATTGTGGA TCCCAATGAT 
TCAGATGTGG AGGAGAATAT ATCCTCTAAA TCTGATTCTG AACAACCCAG TCCTGCCAGC 
TCCAGCTCCA GCTCCAGCTC CAGCTTCACA CCATCCCAGA CCAGGCAACA AGGTCCTTTG 
AGGTCTATAA TGAAAGATCT GCATTCTGAT GACAATGAGG AGGAATCAGA TGAAGTGGAG 
GATAACGACA ATGACTCTGA AATGGAGAGG CCTGTAAATA GAGGAGGCAG CCGAAGTCGC 
AGAGTTAGCT TAAGTGATGG CAGCGATAGT GAAAGCAGTT CTGCTTCTTC ACCCCTACAT 
CACGAACCTC CACCACCCTT ACTAAAAACC AACAACAACC AGATTCTTGA AGTGAAAAGT 
CCAATAAAGC AAAGCAAATC AGATAAGCAA ATAAAGAATG GTGAATGTGA CAAGGCATAC 
CTAGATGAAC TGGTAGAGCT TCACAGAAGG TTAATGACAT TGAGAGAAAG ACACATTCTG 
CAGCAGATCG TGAACCTTAT AGAAGAAACT GGACACTTTC ATATCACAAA CACAACATTT 
GATTTTGATC TTTGCTCGCT GGACAAAACC ACAGTCCGTA AACTACAGAG TTACCTGGAA 
ACATCTGGAA CATCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001273620.1
CDS	213..1910
Translation	MCAVQVKLELGHRAQVRKKPTVEGFTHDWMVFVRGPEHSNIQHFVEKVVFHLHESFPRPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEPRKVRFDYDLFLHLEGHPPVNHLRCEKLTFNNPTEDFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQILEVKSPIKQSKSDKQIKNGECDKAYLDELVELHRRLMTLRERHILQQIVNLIEETGHFHITNTTFDFDLCSLDKTTVRKLQSYLETSGTS

Target ORF information:

RefSeq Version	NM_001286691.1
Organism	Homo sapiens(human)
Definition	Homo sapiens MLLT3 super elongation complex subunit (MLLT3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001286691.1

ORF Insert Sequence:

ATGTGTGCCG TGCAGGTGAA GCTGGAGCTG GGGCACCGCG CCCAGGTGAG GAAAAAACCC 
ACCGTGGAGG GCTTCACCCA CGACTGGATG GTGTTCGTAC GCGGTCCGGA GCACAGTAAC 
ATACAGCACT TTGTGGAGAA AGTCGTCTTC CACTTGCACG AAAGCTTTCC TAGGCCAAAA 
AGAGTGTGCA AAGATCCACC TTACAAAGTA GAAGAATCTG GGTATGCTGG TTTCATTTTG 
CCAATTGAAG TTTATTTTAA AAACAAGGAA GAACCTAGGA AAGTCCGCTT TGATTATGAC 
TTATTCCTGC ATCTTGAAGG CCATCCACCA GTGAATCACC TCCGCTGTGA AAAGCTAACT 
TTCAACAACC CCACAGAGGA CTTTAGGAGA AAGTTGCTGA AGGCAGGAGG GGACCCTAAT 
AGGAGTATTC ATACCAGCAG CAGCAGCAGC AGCAGCAGTA GCAGCAGCAG CAGCAGCAGC 
AGCAGCAGCA GTAGCAGCAG CAGCAGCAGC AGCAGCAGCA GCAGTAGCAG CAGCAGTAGC 
AGCAGCAGCA GCAGCAGTAG TACCAGTTTT TCAAAGCCTC ACAAATTAAT GAAGGAGCAC 
AAGGAAAAAC CTTCTAAAGA CTCCAGAGAA CATAAAAGTG CCTTCAAAGA ACCTTCCAGG 
GATCACAACA AATCTTCCAA AGAATCCTCT AAGAAACCCA AAGAAAATAA ACCACTGAAA 
GAAGAGAAAA TAGTTCCTAA GATGGCCTTC AAGGAACCTA AACCCATGTC AAAAGAGCCA 
AAACCAGATA GTAACTTACT CACCATCACC AGTGGACAAG ATAAGAAGGC TCCTAGTAAA 
AGGCCGCCCA TTTCAGATTC TGAAGAACTC TCAGCCAAAA AAAGGAAAAA GAGTAGCTCA 
GAGGCTTTAT TTAAAAGTTT TTCTAGCGCA CCACCACTGA TACTCACTTG TTCTGCTGAC 
AAAAAACAGA TAAAAGATAA ATCTCATGTC AAGATGGGAA AGGTCAAAAT TGAAAGTGAG 
ACATCAGAGA AGAAGAAATC AACGTTACCG CCATTTGATG ATATTGTGGA TCCCAATGAT 
TCAGATGTGG AGGAGAATAT ATCCTCTAAA TCTGATTCTG AACAACCCAG TCCTGCCAGC 
TCCAGCTCCA GCTCCAGCTC CAGCTTCACA CCATCCCAGA CCAGGCAACA AGGTCCTTTG 
AGGTCTATAA TGAAAGATCT GCATTCTGAT GACAATGAGG AGGAATCAGA TGAAGTGGAG 
GATAACGACA ATGACTCTGA AATGGAGAGG CCTGTAAATA GAGGAGGCAG CCGAAGTCGC 
AGAGTTAGCT TAAGTGATGG CAGCGATAGT GAAAGCAGTT CTGCTTCTTC ACCCCTACAT 
CACGAACCTC CACCACCCTT ACTAAAAACC AACAACAACC AGATTCTTGA AGTGAAAAGT 
CCAATAAAGC AAAGCAAATC AGATAAGCAA ATAAAGAATG GTGAATGTGA CAAGGCATAC 
CTAGATGAAC TGGTAGAGCT TCACAGAAGG TTAATGACAT TGAGAGAAAG ACACATTCTG 
CAGCAGATCG TGAACCTTAT AGAAGAAACT GGACACTTTC ATATCACAAA CACAACATTT 
GATTTTGATC TTTGCTCGCT GGACAAAACC ACAGTCCGTA AACTACAGAG TTACCTGGAA 
ACATCTGGAA CATCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MLLT3 ( XM_017014726.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016870215.1 Homo sapiens MLLT3 super elongation complex subunit (MLLT3), transcript variant X1, mRNA.

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CloneID	OHu98654
Clone ID Related Accession (Same CDS sequence)	XM_017014726.2 , XM_017014726.1
Accession Version	XM_017014726.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1563bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein AF-9 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017014726.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTAGCT CGTGTGCCGT GCAGGTGAAG CTGGAGCTGG GGCACCGCGC CCAGGTGAGG 
AAAAAACCCA CCGTGGAGGG CTTCACCCAC GACTGGATGG TGTTCGTACG CGGTCCGGAG 
CACAGTAACA TACAGCACTT TGTGGAGAAA GTCGTCTTCC ACTTGCACGA AAGCTTTCCT 
AGGCCAAAAA GAGTGTGCAA AGATCCACCT TACAAAGTAG AAGAATCTGG GTATGCTGGT 
TTCATTTTGC CAATTGAAGT TTATTTTAAA AACAAGGAAG AACCTAGGAA AGTCCGCTTT 
GATTATGACT TATTCCTGCA TCTTGAAGGC CATCCACCAG TGAATCACCT CCGCTGTGAA 
AAGCTAACTT TCAACAACCC CACAGAGGAC TTTAGGAGAA AGTTGCTGAA GGCAGGAGGG 
GACCCTAATA GGAGTATTCA TACCAGCAGC AGCAGCAGCA GCAGCAGTAG CAGCAGCAGC 
AGCAGCAGCA GCAGCAGCAG TAGCAGCAGC AGCAGCAGCA GCAGCAGCAG CAGTAGCAGC 
AGCAGTAGCA GCAGCAGCAG CAGCAGTAGT ACCAGTTTTT CAAAGCCTCA CAAATTAATG 
AAGGAGCACA AGGAAAAACC TTCTAAAGAC TCCAGAGAAC ATAAAAGTGC CTTCAAAGAA 
CCTTCCAGGG ATCACAACAA ATCTTCCAAA GAATCCTCTA AGAAACCCAA AGAAAATAAA 
CCACTGAAAG AAGAGAAAAT AGTTCCTAAG ATGGCCTTCA AGGAACCTAA ACCCATGTCA 
AAAGAGCCAA AACCAGATAG TAACTTACTC ACCATCACCA GTGGACAAGA TAAGAAGGCT 
CCTAGTAAAA GGCCGCCCAT TTCAGATTCT GAAGAACTCT CAGCCAAAAA AAGGAAAAAG 
AGTAGCTCAG AGGCTTTATT TAAAAGTTTT TCTAGCGCAC CACCACTGAT ACTCACTTGT 
TCTGCTGACA AAAAACAGAT AAAAGATAAA TCTCATGTCA AGATGGGAAA GGTCAAAATT 
GAAAGTGAGA CATCAGAGAA GAAGAAATCA ACGTTACCGC CATTTGATGA TATTGTGGAT 
CCCAATGATT CAGATGTGGA GGAGAATATA TCCTCTAAAT CTGATTCTGA ACAACCCAGT 
CCTGCCAGCT CCAGCTCCAG CTCCAGCTCC AGCTTCACAC CATCCCAGAC CAGGCAACAA 
GGTCCTTTGA GGTCTATAAT GAAAGATCTG CATTCTGATG ACAATGAGGA GGAATCAGAT 
GAAGTGGAGG ATAACGACAA TGACTCTGAA ATGGAGAGGC CTGTAAATAG AGGAGGCAGC 
CGAAGTCGCA GAGTTAGCTT AAGTGATGGC AGCGATAGTG AAAGCAGTTC TGCTTCTTCA 
CCCCTACATC ACGAACCTCC ACCACCCTTA CTAAAAACCA ACAACAACCA GATCGTGAAC 
CTTATAGAAG AAACTGGACA CTTTCATATC ACAAACACAA CATTTGATTT TGATCTTTGC 
TCGCTGGACA AAACCACAGT CCGTAAACTA CAGAGTTACC TGGAAACATC TGGAACATCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016870215.1
CDS	244..1806
Translation	MASSCAVQVKLELGHRAQVRKKPTVEGFTHDWMVFVRGPEHSNIQHFVEKVVFHLHESFPRPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEPRKVRFDYDLFLHLEGHPPVNHLRCEKLTFNNPTEDFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQIVNLIEETGHFHITNTTFDFDLCSLDKTTVRKLQSYLETSGTS

Target ORF information:

RefSeq Version	XM_017014726.2
Organism	Homo sapiens(human)
Definition	Homo sapiens MLLT3 super elongation complex subunit (MLLT3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017014726.2

ORF Insert Sequence:

ATGGCTAGCT CGTGTGCCGT GCAGGTGAAG CTGGAGCTGG GGCACCGCGC CCAGGTGAGG 
AAAAAACCCA CCGTGGAGGG CTTCACCCAC GACTGGATGG TGTTCGTACG CGGTCCGGAG 
CACAGTAACA TACAGCACTT TGTGGAGAAA GTCGTCTTCC ACTTGCACGA AAGCTTTCCT 
AGGCCAAAAA GAGTGTGCAA AGATCCACCT TACAAAGTAG AAGAATCTGG GTATGCTGGT 
TTCATTTTGC CAATTGAAGT TTATTTTAAA AACAAGGAAG AACCTAGGAA AGTCCGCTTT 
GATTATGACT TATTCCTGCA TCTTGAAGGC CATCCACCAG TGAATCACCT CCGCTGTGAA 
AAGCTAACTT TCAACAACCC CACAGAGGAC TTTAGGAGAA AGTTGCTGAA GGCAGGAGGG 
GACCCTAATA GGAGTATTCA TACCAGCAGC AGCAGCAGCA GCAGCAGTAG CAGCAGCAGC 
AGCAGCAGCA GCAGCAGCAG TAGCAGCAGC AGCAGCAGCA GCAGCAGCAG CAGTAGCAGC 
AGCAGTAGCA GCAGCAGCAG CAGCAGTAGT ACCAGTTTTT CAAAGCCTCA CAAATTAATG 
AAGGAGCACA AGGAAAAACC TTCTAAAGAC TCCAGAGAAC ATAAAAGTGC CTTCAAAGAA 
CCTTCCAGGG ATCACAACAA ATCTTCCAAA GAATCCTCTA AGAAACCCAA AGAAAATAAA 
CCACTGAAAG AAGAGAAAAT AGTTCCTAAG ATGGCCTTCA AGGAACCTAA ACCCATGTCA 
AAAGAGCCAA AACCAGATAG TAACTTACTC ACCATCACCA GTGGACAAGA TAAGAAGGCT 
CCTAGTAAAA GGCCGCCCAT TTCAGATTCT GAAGAACTCT CAGCCAAAAA AAGGAAAAAG 
AGTAGCTCAG AGGCTTTATT TAAAAGTTTT TCTAGCGCAC CACCACTGAT ACTCACTTGT 
TCTGCTGACA AAAAACAGAT AAAAGATAAA TCTCATGTCA AGATGGGAAA GGTCAAAATT 
GAAAGTGAGA CATCAGAGAA GAAGAAATCA ACGTTACCGC CATTTGATGA TATTGTGGAT 
CCCAATGATT CAGATGTGGA GGAGAATATA TCCTCTAAAT CTGATTCTGA ACAACCCAGT 
CCTGCCAGCT CCAGCTCCAG CTCCAGCTCC AGCTTCACAC CATCCCAGAC CAGGCAACAA 
GGTCCTTTGA GGTCTATAAT GAAAGATCTG CATTCTGATG ACAATGAGGA GGAATCAGAT 
GAAGTGGAGG ATAACGACAA TGACTCTGAA ATGGAGAGGC CTGTAAATAG AGGAGGCAGC 
CGAAGTCGCA GAGTTAGCTT AAGTGATGGC AGCGATAGTG AAAGCAGTTC TGCTTCTTCA 
CCCCTACATC ACGAACCTCC ACCACCCTTA CTAAAAACCA ACAACAACCA GATCGTGAAC 
CTTATAGAAG AAACTGGACA CTTTCATATC ACAAACACAA CATTTGATTT TGATCTTTGC 
TCGCTGGACA AAACCACAGT CCGTAAACTA CAGAGTTACC TGGAAACATC TGGAACATCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MLLT3 ( XM_017014726.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016870215.1 Homo sapiens myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3 (MLLT3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu98654
Clone ID Related Accession (Same CDS sequence)	XM_017014726.2 , XM_017014726.1
Accession Version	XM_017014726.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1563bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	protein AF-9 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTAGCT CGTGTGCCGT GCAGGTGAAG CTGGAGCTGG GGCACCGCGC CCAGGTGAGG 
AAAAAACCCA CCGTGGAGGG CTTCACCCAC GACTGGATGG TGTTCGTACG CGGTCCGGAG 
CACAGTAACA TACAGCACTT TGTGGAGAAA GTCGTCTTCC ACTTGCACGA AAGCTTTCCT 
AGGCCAAAAA GAGTGTGCAA AGATCCACCT TACAAAGTAG AAGAATCTGG GTATGCTGGT 
TTCATTTTGC CAATTGAAGT TTATTTTAAA AACAAGGAAG AACCTAGGAA AGTCCGCTTT 
GATTATGACT TATTCCTGCA TCTTGAAGGC CATCCACCAG TGAATCACCT CCGCTGTGAA 
AAGCTAACTT TCAACAACCC CACAGAGGAC TTTAGGAGAA AGTTGCTGAA GGCAGGAGGG 
GACCCTAATA GGAGTATTCA TACCAGCAGC AGCAGCAGCA GCAGCAGTAG CAGCAGCAGC 
AGCAGCAGCA GCAGCAGCAG TAGCAGCAGC AGCAGCAGCA GCAGCAGCAG CAGTAGCAGC 
AGCAGTAGCA GCAGCAGCAG CAGCAGTAGT ACCAGTTTTT CAAAGCCTCA CAAATTAATG 
AAGGAGCACA AGGAAAAACC TTCTAAAGAC TCCAGAGAAC ATAAAAGTGC CTTCAAAGAA 
CCTTCCAGGG ATCACAACAA ATCTTCCAAA GAATCCTCTA AGAAACCCAA AGAAAATAAA 
CCACTGAAAG AAGAGAAAAT AGTTCCTAAG ATGGCCTTCA AGGAACCTAA ACCCATGTCA 
AAAGAGCCAA AACCAGATAG TAACTTACTC ACCATCACCA GTGGACAAGA TAAGAAGGCT 
CCTAGTAAAA GGCCGCCCAT TTCAGATTCT GAAGAACTCT CAGCCAAAAA AAGGAAAAAG 
AGTAGCTCAG AGGCTTTATT TAAAAGTTTT TCTAGCGCAC CACCACTGAT ACTCACTTGT 
TCTGCTGACA AAAAACAGAT AAAAGATAAA TCTCATGTCA AGATGGGAAA GGTCAAAATT 
GAAAGTGAGA CATCAGAGAA GAAGAAATCA ACGTTACCGC CATTTGATGA TATTGTGGAT 
CCCAATGATT CAGATGTGGA GGAGAATATA TCCTCTAAAT CTGATTCTGA ACAACCCAGT 
CCTGCCAGCT CCAGCTCCAG CTCCAGCTCC AGCTTCACAC CATCCCAGAC CAGGCAACAA 
GGTCCTTTGA GGTCTATAAT GAAAGATCTG CATTCTGATG ACAATGAGGA GGAATCAGAT 
GAAGTGGAGG ATAACGACAA TGACTCTGAA ATGGAGAGGC CTGTAAATAG AGGAGGCAGC 
CGAAGTCGCA GAGTTAGCTT AAGTGATGGC AGCGATAGTG AAAGCAGTTC TGCTTCTTCA 
CCCCTACATC ACGAACCTCC ACCACCCTTA CTAAAAACCA ACAACAACCA GATCGTGAAC 
CTTATAGAAG AAACTGGACA CTTTCATATC ACAAACACAA CATTTGATTT TGATCTTTGC 
TCGCTGGACA AAACCACAGT CCGTAAACTA CAGAGTTACC TGGAAACATC TGGAACATCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016870215.1
CDS	203..1765
Translation	MASSCAVQVKLELGHRAQVRKKPTVEGFTHDWMVFVRGPEHSNIQHFVEKVVFHLHESFPRPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEPRKVRFDYDLFLHLEGHPPVNHLRCEKLTFNNPTEDFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQIVNLIEETGHFHITNTTFDFDLCSLDKTTVRKLQSYLETSGTS

Target ORF information:

RefSeq Version	XM_017014726.1
Organism	Homo sapiens(human)
Definition	Homo sapiens myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3 (MLLT3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017014726.1

ORF Insert Sequence:

ATGGCTAGCT CGTGTGCCGT GCAGGTGAAG CTGGAGCTGG GGCACCGCGC CCAGGTGAGG 
AAAAAACCCA CCGTGGAGGG CTTCACCCAC GACTGGATGG TGTTCGTACG CGGTCCGGAG 
CACAGTAACA TACAGCACTT TGTGGAGAAA GTCGTCTTCC ACTTGCACGA AAGCTTTCCT 
AGGCCAAAAA GAGTGTGCAA AGATCCACCT TACAAAGTAG AAGAATCTGG GTATGCTGGT 
TTCATTTTGC CAATTGAAGT TTATTTTAAA AACAAGGAAG AACCTAGGAA AGTCCGCTTT 
GATTATGACT TATTCCTGCA TCTTGAAGGC CATCCACCAG TGAATCACCT CCGCTGTGAA 
AAGCTAACTT TCAACAACCC CACAGAGGAC TTTAGGAGAA AGTTGCTGAA GGCAGGAGGG 
GACCCTAATA GGAGTATTCA TACCAGCAGC AGCAGCAGCA GCAGCAGTAG CAGCAGCAGC 
AGCAGCAGCA GCAGCAGCAG TAGCAGCAGC AGCAGCAGCA GCAGCAGCAG CAGTAGCAGC 
AGCAGTAGCA GCAGCAGCAG CAGCAGTAGT ACCAGTTTTT CAAAGCCTCA CAAATTAATG 
AAGGAGCACA AGGAAAAACC TTCTAAAGAC TCCAGAGAAC ATAAAAGTGC CTTCAAAGAA 
CCTTCCAGGG ATCACAACAA ATCTTCCAAA GAATCCTCTA AGAAACCCAA AGAAAATAAA 
CCACTGAAAG AAGAGAAAAT AGTTCCTAAG ATGGCCTTCA AGGAACCTAA ACCCATGTCA 
AAAGAGCCAA AACCAGATAG TAACTTACTC ACCATCACCA GTGGACAAGA TAAGAAGGCT 
CCTAGTAAAA GGCCGCCCAT TTCAGATTCT GAAGAACTCT CAGCCAAAAA AAGGAAAAAG 
AGTAGCTCAG AGGCTTTATT TAAAAGTTTT TCTAGCGCAC CACCACTGAT ACTCACTTGT 
TCTGCTGACA AAAAACAGAT AAAAGATAAA TCTCATGTCA AGATGGGAAA GGTCAAAATT 
GAAAGTGAGA CATCAGAGAA GAAGAAATCA ACGTTACCGC CATTTGATGA TATTGTGGAT 
CCCAATGATT CAGATGTGGA GGAGAATATA TCCTCTAAAT CTGATTCTGA ACAACCCAGT 
CCTGCCAGCT CCAGCTCCAG CTCCAGCTCC AGCTTCACAC CATCCCAGAC CAGGCAACAA 
GGTCCTTTGA GGTCTATAAT GAAAGATCTG CATTCTGATG ACAATGAGGA GGAATCAGAT 
GAAGTGGAGG ATAACGACAA TGACTCTGAA ATGGAGAGGC CTGTAAATAG AGGAGGCAGC 
CGAAGTCGCA GAGTTAGCTT AAGTGATGGC AGCGATAGTG AAAGCAGTTC TGCTTCTTCA 
CCCCTACATC ACGAACCTCC ACCACCCTTA CTAAAAACCA ACAACAACCA GATCGTGAAC 
CTTATAGAAG AAACTGGACA CTTTCATATC ACAAACACAA CATTTGATTT TGATCTTTGC 
TCGCTGGACA AAACCACAGT CCGTAAACTA CAGAGTTACC TGGAAACATC TGGAACATCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MLLT3 ( XM_017014727.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016870216.1 Homo sapiens MLLT3 super elongation complex subunit (MLLT3), transcript variant X2, mRNA.

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CloneID	OHu98655
Clone ID Related Accession (Same CDS sequence)	XM_017014727.1
Accession Version	XM_017014727.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1554bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein AF-9 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGTGCCG TGCAGGTGAA GCTGGAGCTG GGGCACCGCG CCCAGGTGAG GAAAAAACCC 
ACCGTGGAGG GCTTCACCCA CGACTGGATG GTGTTCGTAC GCGGTCCGGA GCACAGTAAC 
ATACAGCACT TTGTGGAGAA AGTCGTCTTC CACTTGCACG AAAGCTTTCC TAGGCCAAAA 
AGAGTGTGCA AAGATCCACC TTACAAAGTA GAAGAATCTG GGTATGCTGG TTTCATTTTG 
CCAATTGAAG TTTATTTTAA AAACAAGGAA GAACCTAGGA AAGTCCGCTT TGATTATGAC 
TTATTCCTGC ATCTTGAAGG CCATCCACCA GTGAATCACC TCCGCTGTGA AAAGCTAACT 
TTCAACAACC CCACAGAGGA CTTTAGGAGA AAGTTGCTGA AGGCAGGAGG GGACCCTAAT 
AGGAGTATTC ATACCAGCAG CAGCAGCAGC AGCAGCAGTA GCAGCAGCAG CAGCAGCAGC 
AGCAGCAGCA GTAGCAGCAG CAGCAGCAGC AGCAGCAGCA GCAGTAGCAG CAGCAGTAGC 
AGCAGCAGCA GCAGCAGTAG TACCAGTTTT TCAAAGCCTC ACAAATTAAT GAAGGAGCAC 
AAGGAAAAAC CTTCTAAAGA CTCCAGAGAA CATAAAAGTG CCTTCAAAGA ACCTTCCAGG 
GATCACAACA AATCTTCCAA AGAATCCTCT AAGAAACCCA AAGAAAATAA ACCACTGAAA 
GAAGAGAAAA TAGTTCCTAA GATGGCCTTC AAGGAACCTA AACCCATGTC AAAAGAGCCA 
AAACCAGATA GTAACTTACT CACCATCACC AGTGGACAAG ATAAGAAGGC TCCTAGTAAA 
AGGCCGCCCA TTTCAGATTC TGAAGAACTC TCAGCCAAAA AAAGGAAAAA GAGTAGCTCA 
GAGGCTTTAT TTAAAAGTTT TTCTAGCGCA CCACCACTGA TACTCACTTG TTCTGCTGAC 
AAAAAACAGA TAAAAGATAA ATCTCATGTC AAGATGGGAA AGGTCAAAAT TGAAAGTGAG 
ACATCAGAGA AGAAGAAATC AACGTTACCG CCATTTGATG ATATTGTGGA TCCCAATGAT 
TCAGATGTGG AGGAGAATAT ATCCTCTAAA TCTGATTCTG AACAACCCAG TCCTGCCAGC 
TCCAGCTCCA GCTCCAGCTC CAGCTTCACA CCATCCCAGA CCAGGCAACA AGGTCCTTTG 
AGGTCTATAA TGAAAGATCT GCATTCTGAT GACAATGAGG AGGAATCAGA TGAAGTGGAG 
GATAACGACA ATGACTCTGA AATGGAGAGG CCTGTAAATA GAGGAGGCAG CCGAAGTCGC 
AGAGTTAGCT TAAGTGATGG CAGCGATAGT GAAAGCAGTT CTGCTTCTTC ACCCCTACAT 
CACGAACCTC CACCACCCTT ACTAAAAACC AACAACAACC AGATCGTGAA CCTTATAGAA 
GAAACTGGAC ACTTTCATAT CACAAACACA ACATTTGATT TTGATCTTTG CTCGCTGGAC 
AAAACCACAG TCCGTAAACT ACAGAGTTAC CTGGAAACAT CTGGAACATC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016870216.1
CDS	208..1761
Translation	MCAVQVKLELGHRAQVRKKPTVEGFTHDWMVFVRGPEHSNIQHFVEKVVFHLHESFPRPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEPRKVRFDYDLFLHLEGHPPVNHLRCEKLTFNNPTEDFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQIVNLIEETGHFHITNTTFDFDLCSLDKTTVRKLQSYLETSGTS

Target ORF information:

RefSeq Version	XM_017014727.1
Organism	Homo sapiens(human)
Definition	Homo sapiens MLLT3 super elongation complex subunit (MLLT3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017014727.1

ORF Insert Sequence:

ATGTGTGCCG TGCAGGTGAA GCTGGAGCTG GGGCACCGCG CCCAGGTGAG GAAAAAACCC 
ACCGTGGAGG GCTTCACCCA CGACTGGATG GTGTTCGTAC GCGGTCCGGA GCACAGTAAC 
ATACAGCACT TTGTGGAGAA AGTCGTCTTC CACTTGCACG AAAGCTTTCC TAGGCCAAAA 
AGAGTGTGCA AAGATCCACC TTACAAAGTA GAAGAATCTG GGTATGCTGG TTTCATTTTG 
CCAATTGAAG TTTATTTTAA AAACAAGGAA GAACCTAGGA AAGTCCGCTT TGATTATGAC 
TTATTCCTGC ATCTTGAAGG CCATCCACCA GTGAATCACC TCCGCTGTGA AAAGCTAACT 
TTCAACAACC CCACAGAGGA CTTTAGGAGA AAGTTGCTGA AGGCAGGAGG GGACCCTAAT 
AGGAGTATTC ATACCAGCAG CAGCAGCAGC AGCAGCAGTA GCAGCAGCAG CAGCAGCAGC 
AGCAGCAGCA GTAGCAGCAG CAGCAGCAGC AGCAGCAGCA GCAGTAGCAG CAGCAGTAGC 
AGCAGCAGCA GCAGCAGTAG TACCAGTTTT TCAAAGCCTC ACAAATTAAT GAAGGAGCAC 
AAGGAAAAAC CTTCTAAAGA CTCCAGAGAA CATAAAAGTG CCTTCAAAGA ACCTTCCAGG 
GATCACAACA AATCTTCCAA AGAATCCTCT AAGAAACCCA AAGAAAATAA ACCACTGAAA 
GAAGAGAAAA TAGTTCCTAA GATGGCCTTC AAGGAACCTA AACCCATGTC AAAAGAGCCA 
AAACCAGATA GTAACTTACT CACCATCACC AGTGGACAAG ATAAGAAGGC TCCTAGTAAA 
AGGCCGCCCA TTTCAGATTC TGAAGAACTC TCAGCCAAAA AAAGGAAAAA GAGTAGCTCA 
GAGGCTTTAT TTAAAAGTTT TTCTAGCGCA CCACCACTGA TACTCACTTG TTCTGCTGAC 
AAAAAACAGA TAAAAGATAA ATCTCATGTC AAGATGGGAA AGGTCAAAAT TGAAAGTGAG 
ACATCAGAGA AGAAGAAATC AACGTTACCG CCATTTGATG ATATTGTGGA TCCCAATGAT 
TCAGATGTGG AGGAGAATAT ATCCTCTAAA TCTGATTCTG AACAACCCAG TCCTGCCAGC 
TCCAGCTCCA GCTCCAGCTC CAGCTTCACA CCATCCCAGA CCAGGCAACA AGGTCCTTTG 
AGGTCTATAA TGAAAGATCT GCATTCTGAT GACAATGAGG AGGAATCAGA TGAAGTGGAG 
GATAACGACA ATGACTCTGA AATGGAGAGG CCTGTAAATA GAGGAGGCAG CCGAAGTCGC 
AGAGTTAGCT TAAGTGATGG CAGCGATAGT GAAAGCAGTT CTGCTTCTTC ACCCCTACAT 
CACGAACCTC CACCACCCTT ACTAAAAACC AACAACAACC AGATCGTGAA CCTTATAGAA 
GAAACTGGAC ACTTTCATAT CACAAACACA ACATTTGATT TTGATCTTTG CTCGCTGGAC 
AAAACCACAG TCCGTAAACT ACAGAGTTAC CTGGAAACAT CTGGAACATC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

miR-564 inhibited metastasis and proliferation of prostate cancer by targeting MLLT3.
European review for medical and pharmacological sciences21(21)4828-4834(2017 Nov)
Meng FJ,Meng FM,Wu HX,Cao XF

MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in 11q23 acute myeloid leukemia.
Oncogene36(23)3346-3356(2017 Jun)
Prange KHM,Mandoli A,Kuznetsova T,Wang SY,Sotoca AM,Marneth AE,van der Reijden BA,Stunnenberg HG,Martens JHA

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

Structural Insights into Histone Crotonyl-Lysine Recognition by the AF9 YEATS Domain.
Structure (London, England : 1993)24(9)1606-12(2016 09)
Zhang Q,Zeng L,Zhao C,Ju Y,Konuma T,Zhou MM

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MLLT3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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