Gene Symbol | MFGE8 |
Entrez Gene ID | 4240 |
Full Name | milk fat globule-EGF factor 8 protein |
Synonyms | BA46,EDIL1,HMFG,HsT19888,MFG-E8,MFGM,OAcGD3S,SED1,SPAG10,hP47 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a preproprotein that is proteolytically processed to form multiple protein products. The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells. This protein has also been implicated in wound healing, autoimmune disease, and cancer. Lactadherin can be further processed to form a smaller cleavage product, medin, which comprises the major protein component of aortic medial amyloid (AMA). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]. |
Disorder MIM: |