MAGEA8 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MAGEA8
Entrez Gene ID	4107
Full Name	MAGE family member A8
Synonyms	CT1.8,MAGE8
General protein information	Preferred Names MAGE family member A8 Names melanoma-associated antigen 8 MAGE-8 antigen cancer/testis antigen 1.8 cancer/testis antigen family 1, member 8 melanoma antigen family A, 8 melanoma antigen family A8
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xq28
Summary	This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Oct 2009].
Disorder MIM:	300341

mRNA and Protein(s)

mRNA	Protein	Name
NM_001166400.1	NP_001159872.1	melanoma-associated antigen 8
XM_017029520.1	XP_016885009.1	melanoma-associated antigen 8 isoform X1
NM_005364.4	NP_005355.2	melanoma-associated antigen 8
NM_005364.5	NP_005355.2	melanoma-associated antigen 8
NM_001166401.1	NP_001159873.1	melanoma-associated antigen 8

Pathways from BioSystems

Homologies

	LOC706478	XP_002806482.1
Pan troglodytes (chimpanzee)	MAGEA8	XP_529192.1
Homo sapiens (human)	MAGEA8	NP_001159873.1

Gene Ontology
Bibliography

Related articles in PubMed

An inter-species protein-protein interaction network across vast evolutionary distance.
Zhong Q, Pevzner SJ, Hao T, Wang Y, Mosca R, Menche J, Taipale M, Ta?an M, Fan C, Yang X, Haley P, Murray RR, Mer F, Gebreab F, Tam S, MacWilliams A, Dricot A, Reichert P, Santhanam B, Ghamsari L, Calderwood MA, Rolland T, Charloteaux B, Lindquist S, Barab?si AL, Hill DE, Aloy P, Cusick ME, Xia Y, Roth FP, Vidal M
Molecular systems biology12(4)865(2016 Apr)

Widespread macromolecular interaction perturbations in human genetic disorders.
Sahni N, Yi S, Taipale M, Fuxman Bass JI, Coulombe-Huntington J, Yang F, Peng J, Weile J, Karras GI, Wang Y, Kov?cs IA, Kamburov A, Krykbaeva I, Lam MH, Tucker G, Khurana V, Sharma A, Liu YY, Yachie N, Zhong Q, Shen Y, Palagi A, San-Miguel A, Fan C, Balcha D, Dricot A, Jordan DM, Walsh JM, Shah AA, Yang X, Stoyanova AK, Leighton A, Calderwood MA, Jacob Y, Cusick ME, Salehi-Ashtiani K, Whitesell LJ, Sunyaev S, Berger B, Barab?si AL, Charloteaux B, Hill DE, Hao T, Roth FP, Xia Y, Walhout AJM, Lindquist S, Vidal M
Cell161(3)647-660(2015 Apr)

Quantitative evaluation of the expression of MAGE genes in tumors by limiting dilution of cDNA libraries.
Serrano A, Leth? B, Delroisse JM, Lurquin C, De Plaen E, Brasseur F, Rimoldi D, Boon T
International journal of cancer83(5)664-9(1999 Nov)

The melanoma antigen gene (MAGE) family is clustered in the chromosomal band Xq28.
Rogner UC, Wilke K, Steck E, Korn B, Poustka A
Genomics29(3)725-31(1995 Oct)

Structure, chromosomal localization, and expression of 12 genes of the MAGE family.
De Plaen E, Arden K, Traversari C, Gaforio JJ, Szikora JP, De Smet C, Brasseur F, van der Bruggen P, Leth? B, Lurquin C
Immunogenetics40(5)360-9(1994)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following MAGEA8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAGEA8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu12673	NM_001166400.1 Latest version!	Homo sapiens MAGE family member A8 (MAGEA8), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu12673	NM_005364.5 Latest version!	Homo sapiens MAGE family member A8 (MAGEA8), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu12673	NM_001166401.1 Latest version!	Homo sapiens MAGE family member A8 (MAGEA8), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu12673	XM_017029520.1 Latest version!	Homo sapiens MAGE family member A8 (MAGEA8), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu12673	NM_005364.4	Homo sapiens MAGE family member A8 (MAGEA8), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MAGEA8 ( NM_001166400.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001159872.1 Homo sapiens MAGE family member A8 (MAGEA8), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu12673
Clone ID Related Accession (Same CDS sequence)	NM_001166400.1 , XM_017029520.1 , NM_005364.4 , NM_005364.5 , NM_001166401.1
Accession Version	NM_001166400.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 957bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-22
Organism	Homo sapiens(human)
Product	melanoma-associated antigen 8
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK313943.1, AC244099.2, BC002455.2 and AA045817.1. Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 all encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BE729897.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTTCTTG GGCAGAAGAG TCAGCGCTAC AAGGCTGAGG AAGGCCTTCA GGCCCAAGGA 
GAGGCACCAG GGCTTATGGA TGTGCAGATT CCCACAGCTG AGGAGCAGAA GGCTGCATCC 
TCCTCCTCTA CTCTGATCAT GGGAACCCTT GAGGAGGTGA CTGATTCTGG GTCACCAAGT 
CCTCCCCAGA GTCCTGAGGG TGCCTCCTCT TCCCTGACTG TCACCGACAG CACTCTGTGG 
AGCCAATCCG ATGAGGGTTC CAGCAGCAAT GAAGAGGAGG GGCCAAGCAC CTCCCCGGAC 
CCAGCTCACC TGGAGTCCCT GTTCCGGGAA GCACTTGATG AGAAAGTGGC TGAGTTAGTT 
CGTTTCCTGC TCCGCAAATA TCAAATTAAG GAGCCGGTCA CAAAGGCAGA AATGCTTGAG 
AGTGTCATCA AAAATTACAA GAACCACTTT CCTGATATCT TCAGCAAAGC CTCTGAGTGC 
ATGCAGGTGA TCTTTGGCAT TGATGTGAAG GAAGTGGACC CTGCCGGCCA CTCCTACATC 
CTTGTCACCT GCCTGGGCCT CTCCTATGAT GGCCTGCTGG GTGATGATCA GAGTACGCCC 
AAGACCGGCC TCCTGATAAT CGTCCTGGGC ATGATCTTAA TGGAGGGCAG CCGCGCCCCG 
GAGGAGGCAA TCTGGGAAGC GTTGAGTGTG ATGGGGCTGT ATGATGGGAG GGAGCACAGT 
GTCTATTGGA AGCTCAGGAA GCTGCTCACC CAAGAGTGGG TGCAGGAGAA CTACCTGGAG 
TACCGCCAGG CGCCCGGCAG TGATCCTGTG CGCTACGAGT TCCTGTGGGG TCCAAGGGCC 
CTTGCTGAAA CCAGCTATGT GAAAGTCCTG GAGCATGTGG TCAGGGTCAA TGCAAGAGTT 
CGCATTTCCT ACCCATCCCT GCATGAAGAG GCTTTGGGAG AGGAGAAAGG AGTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001159872.1
CDS	550..1506
Translation	MLLGQKSQRYKAEEGLQAQGEAPGLMDVQIPTAEEQKAASSSSTLIMGTLEEVTDSGSPSPPQSPEGASSSLTVTDSTLWSQSDEGSSSNEEEGPSTSPDPAHLESLFREALDEKVAELVRFLLRKYQIKEPVTKAEMLESVIKNYKNHFPDIFSKASECMQVIFGIDVKEVDPAGHSYILVTCLGLSYDGLLGDDQSTPKTGLLIIVLGMILMEGSRAPEEAIWEALSVMGLYDGREHSVYWKLRKLLTQEWVQENYLEYRQAPGSDPVRYEFLWGPRALAETSYVKVLEHVVRVNARVRISYPSLHEEALGEEKGV

Target ORF information:

RefSeq Version	NM_001166400.1
Organism	Homo sapiens(human)
Definition	Homo sapiens MAGE family member A8 (MAGEA8), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001166400.1

ORF Insert Sequence:

ATGCTTCTTG GGCAGAAGAG TCAGCGCTAC AAGGCTGAGG AAGGCCTTCA GGCCCAAGGA 
GAGGCACCAG GGCTTATGGA TGTGCAGATT CCCACAGCTG AGGAGCAGAA GGCTGCATCC 
TCCTCCTCTA CTCTGATCAT GGGAACCCTT GAGGAGGTGA CTGATTCTGG GTCACCAAGT 
CCTCCCCAGA GTCCTGAGGG TGCCTCCTCT TCCCTGACTG TCACCGACAG CACTCTGTGG 
AGCCAATCCG ATGAGGGTTC CAGCAGCAAT GAAGAGGAGG GGCCAAGCAC CTCCCCGGAC 
CCAGCTCACC TGGAGTCCCT GTTCCGGGAA GCACTTGATG AGAAAGTGGC TGAGTTAGTT 
CGTTTCCTGC TCCGCAAATA TCAAATTAAG GAGCCGGTCA CAAAGGCAGA AATGCTTGAG 
AGTGTCATCA AAAATTACAA GAACCACTTT CCTGATATCT TCAGCAAAGC CTCTGAGTGC 
ATGCAGGTGA TCTTTGGCAT TGATGTGAAG GAAGTGGACC CTGCCGGCCA CTCCTACATC 
CTTGTCACCT GCCTGGGCCT CTCCTATGAT GGCCTGCTGG GTGATGATCA GAGTACGCCC 
AAGACCGGCC TCCTGATAAT CGTCCTGGGC ATGATCTTAA TGGAGGGCAG CCGCGCCCCG 
GAGGAGGCAA TCTGGGAAGC GTTGAGTGTG ATGGGGCTGT ATGATGGGAG GGAGCACAGT 
GTCTATTGGA AGCTCAGGAA GCTGCTCACC CAAGAGTGGG TGCAGGAGAA CTACCTGGAG 
TACCGCCAGG CGCCCGGCAG TGATCCTGTG CGCTACGAGT TCCTGTGGGG TCCAAGGGCC 
CTTGCTGAAA CCAGCTATGT GAAAGTCCTG GAGCATGTGG TCAGGGTCAA TGCAAGAGTT 
CGCATTTCCT ACCCATCCCT GCATGAAGAG GCTTTGGGAG AGGAGAAAGG AGTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAGEA8 ( NM_005364.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_005355.2 Homo sapiens MAGE family member A8 (MAGEA8), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu12673
Clone ID Related Accession (Same CDS sequence)	NM_001166400.1 , XM_017029520.1 , NM_005364.4 , NM_005364.5 , NM_001166401.1
Accession Version	NM_005364.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 957bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-26
Organism	Homo sapiens(human)
Product	melanoma-associated antigen 8
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK313943.1, BC002455.2 and AA045817.1. This sequence is a reference standard in the RefSeqGene project. On Oct 23, 2009 this sequence version replaced NM_005364.3. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 all encode the same protein. ##Evidence-Data-START## Transcript exon combination :: AK313943.1, BC002455.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142853 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTTCTTG GGCAGAAGAG TCAGCGCTAC AAGGCTGAGG AAGGCCTTCA GGCCCAAGGA 
GAGGCACCAG GGCTTATGGA TGTGCAGATT CCCACAGCTG AGGAGCAGAA GGCTGCATCC 
TCCTCCTCTA CTCTGATCAT GGGAACCCTT GAGGAGGTGA CTGATTCTGG GTCACCAAGT 
CCTCCCCAGA GTCCTGAGGG TGCCTCCTCT TCCCTGACTG TCACCGACAG CACTCTGTGG 
AGCCAATCCG ATGAGGGTTC CAGCAGCAAT GAAGAGGAGG GGCCAAGCAC CTCCCCGGAC 
CCAGCTCACC TGGAGTCCCT GTTCCGGGAA GCACTTGATG AGAAAGTGGC TGAGTTAGTT 
CGTTTCCTGC TCCGCAAATA TCAAATTAAG GAGCCGGTCA CAAAGGCAGA AATGCTTGAG 
AGTGTCATCA AAAATTACAA GAACCACTTT CCTGATATCT TCAGCAAAGC CTCTGAGTGC 
ATGCAGGTGA TCTTTGGCAT TGATGTGAAG GAAGTGGACC CTGCCGGCCA CTCCTACATC 
CTTGTCACCT GCCTGGGCCT CTCCTATGAT GGCCTGCTGG GTGATGATCA GAGTACGCCC 
AAGACCGGCC TCCTGATAAT CGTCCTGGGC ATGATCTTAA TGGAGGGCAG CCGCGCCCCG 
GAGGAGGCAA TCTGGGAAGC GTTGAGTGTG ATGGGGCTGT ATGATGGGAG GGAGCACAGT 
GTCTATTGGA AGCTCAGGAA GCTGCTCACC CAAGAGTGGG TGCAGGAGAA CTACCTGGAG 
TACCGCCAGG CGCCCGGCAG TGATCCTGTG CGCTACGAGT TCCTGTGGGG TCCAAGGGCC 
CTTGCTGAAA CCAGCTATGT GAAAGTCCTG GAGCATGTGG TCAGGGTCAA TGCAAGAGTT 
CGCATTTCCT ACCCATCCCT GCATGAAGAG GCTTTGGGAG AGGAGAAAGG AGTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005355.2
CDS	271..1227
Translation	MLLGQKSQRYKAEEGLQAQGEAPGLMDVQIPTAEEQKAASSSSTLIMGTLEEVTDSGSPSPPQSPEGASSSLTVTDSTLWSQSDEGSSSNEEEGPSTSPDPAHLESLFREALDEKVAELVRFLLRKYQIKEPVTKAEMLESVIKNYKNHFPDIFSKASECMQVIFGIDVKEVDPAGHSYILVTCLGLSYDGLLGDDQSTPKTGLLIIVLGMILMEGSRAPEEAIWEALSVMGLYDGREHSVYWKLRKLLTQEWVQENYLEYRQAPGSDPVRYEFLWGPRALAETSYVKVLEHVVRVNARVRISYPSLHEEALGEEKGV

Target ORF information:

RefSeq Version	NM_005364.4
Organism	Homo sapiens(human)
Definition	Homo sapiens MAGE family member A8 (MAGEA8), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005364.4

ORF Insert Sequence:

ATGCTTCTTG GGCAGAAGAG TCAGCGCTAC AAGGCTGAGG AAGGCCTTCA GGCCCAAGGA 
GAGGCACCAG GGCTTATGGA TGTGCAGATT CCCACAGCTG AGGAGCAGAA GGCTGCATCC 
TCCTCCTCTA CTCTGATCAT GGGAACCCTT GAGGAGGTGA CTGATTCTGG GTCACCAAGT 
CCTCCCCAGA GTCCTGAGGG TGCCTCCTCT TCCCTGACTG TCACCGACAG CACTCTGTGG 
AGCCAATCCG ATGAGGGTTC CAGCAGCAAT GAAGAGGAGG GGCCAAGCAC CTCCCCGGAC 
CCAGCTCACC TGGAGTCCCT GTTCCGGGAA GCACTTGATG AGAAAGTGGC TGAGTTAGTT 
CGTTTCCTGC TCCGCAAATA TCAAATTAAG GAGCCGGTCA CAAAGGCAGA AATGCTTGAG 
AGTGTCATCA AAAATTACAA GAACCACTTT CCTGATATCT TCAGCAAAGC CTCTGAGTGC 
ATGCAGGTGA TCTTTGGCAT TGATGTGAAG GAAGTGGACC CTGCCGGCCA CTCCTACATC 
CTTGTCACCT GCCTGGGCCT CTCCTATGAT GGCCTGCTGG GTGATGATCA GAGTACGCCC 
AAGACCGGCC TCCTGATAAT CGTCCTGGGC ATGATCTTAA TGGAGGGCAG CCGCGCCCCG 
GAGGAGGCAA TCTGGGAAGC GTTGAGTGTG ATGGGGCTGT ATGATGGGAG GGAGCACAGT 
GTCTATTGGA AGCTCAGGAA GCTGCTCACC CAAGAGTGGG TGCAGGAGAA CTACCTGGAG 
TACCGCCAGG CGCCCGGCAG TGATCCTGTG CGCTACGAGT TCCTGTGGGG TCCAAGGGCC 
CTTGCTGAAA CCAGCTATGT GAAAGTCCTG GAGCATGTGG TCAGGGTCAA TGCAAGAGTT 
CGCATTTCCT ACCCATCCCT GCATGAAGAG GCTTTGGGAG AGGAGAAAGG AGTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAGEA8 ( NM_005364.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_005355.2 Homo sapiens MAGE family member A8 (MAGEA8), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu12673
Clone ID Related Accession (Same CDS sequence)	NM_001166400.1 , XM_017029520.1 , NM_005364.4 , NM_005364.5 , NM_001166401.1
Accession Version	NM_005364.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 957bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-24
Organism	Homo sapiens(human)
Product	melanoma-associated antigen 8
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK313943.1 and BC002455.2. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_005364.4. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 all encode the same protein. ##Evidence-Data-START## Transcript exon combination :: SRR5189667.352954.1, SRR5189667.124238.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142853 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000286482.6/ ENSP00000286482.1 RefSeq Select criteria :: based on expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCTTCTTG GGCAGAAGAG TCAGCGCTAC AAGGCTGAGG AAGGCCTTCA GGCCCAAGGA 
GAGGCACCAG GGCTTATGGA TGTGCAGATT CCCACAGCTG AGGAGCAGAA GGCTGCATCC 
TCCTCCTCTA CTCTGATCAT GGGAACCCTT GAGGAGGTGA CTGATTCTGG GTCACCAAGT 
CCTCCCCAGA GTCCTGAGGG TGCCTCCTCT TCCCTGACTG TCACCGACAG CACTCTGTGG 
AGCCAATCCG ATGAGGGTTC CAGCAGCAAT GAAGAGGAGG GGCCAAGCAC CTCCCCGGAC 
CCAGCTCACC TGGAGTCCCT GTTCCGGGAA GCACTTGATG AGAAAGTGGC TGAGTTAGTT 
CGTTTCCTGC TCCGCAAATA TCAAATTAAG GAGCCGGTCA CAAAGGCAGA AATGCTTGAG 
AGTGTCATCA AAAATTACAA GAACCACTTT CCTGATATCT TCAGCAAAGC CTCTGAGTGC 
ATGCAGGTGA TCTTTGGCAT TGATGTGAAG GAAGTGGACC CTGCCGGCCA CTCCTACATC 
CTTGTCACCT GCCTGGGCCT CTCCTATGAT GGCCTGCTGG GTGATGATCA GAGTACGCCC 
AAGACCGGCC TCCTGATAAT CGTCCTGGGC ATGATCTTAA TGGAGGGCAG CCGCGCCCCG 
GAGGAGGCAA TCTGGGAAGC GTTGAGTGTG ATGGGGCTGT ATGATGGGAG GGAGCACAGT 
GTCTATTGGA AGCTCAGGAA GCTGCTCACC CAAGAGTGGG TGCAGGAGAA CTACCTGGAG 
TACCGCCAGG CGCCCGGCAG TGATCCTGTG CGCTACGAGT TCCTGTGGGG TCCAAGGGCC 
CTTGCTGAAA CCAGCTATGT GAAAGTCCTG GAGCATGTGG TCAGGGTCAA TGCAAGAGTT 
CGCATTTCCT ACCCATCCCT GCATGAAGAG GCTTTGGGAG AGGAGAAAGG AGTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005355.2
CDS	229..1185
Translation	MLLGQKSQRYKAEEGLQAQGEAPGLMDVQIPTAEEQKAASSSSTLIMGTLEEVTDSGSPSPPQSPEGASSSLTVTDSTLWSQSDEGSSSNEEEGPSTSPDPAHLESLFREALDEKVAELVRFLLRKYQIKEPVTKAEMLESVIKNYKNHFPDIFSKASECMQVIFGIDVKEVDPAGHSYILVTCLGLSYDGLLGDDQSTPKTGLLIIVLGMILMEGSRAPEEAIWEALSVMGLYDGREHSVYWKLRKLLTQEWVQENYLEYRQAPGSDPVRYEFLWGPRALAETSYVKVLEHVVRVNARVRISYPSLHEEALGEEKGV

Target ORF information:

RefSeq Version	NM_005364.5
Organism	Homo sapiens(human)
Definition	Homo sapiens MAGE family member A8 (MAGEA8), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005364.5

ORF Insert Sequence:

ATGCTTCTTG GGCAGAAGAG TCAGCGCTAC AAGGCTGAGG AAGGCCTTCA GGCCCAAGGA 
GAGGCACCAG GGCTTATGGA TGTGCAGATT CCCACAGCTG AGGAGCAGAA GGCTGCATCC 
TCCTCCTCTA CTCTGATCAT GGGAACCCTT GAGGAGGTGA CTGATTCTGG GTCACCAAGT 
CCTCCCCAGA GTCCTGAGGG TGCCTCCTCT TCCCTGACTG TCACCGACAG CACTCTGTGG 
AGCCAATCCG ATGAGGGTTC CAGCAGCAAT GAAGAGGAGG GGCCAAGCAC CTCCCCGGAC 
CCAGCTCACC TGGAGTCCCT GTTCCGGGAA GCACTTGATG AGAAAGTGGC TGAGTTAGTT 
CGTTTCCTGC TCCGCAAATA TCAAATTAAG GAGCCGGTCA CAAAGGCAGA AATGCTTGAG 
AGTGTCATCA AAAATTACAA GAACCACTTT CCTGATATCT TCAGCAAAGC CTCTGAGTGC 
ATGCAGGTGA TCTTTGGCAT TGATGTGAAG GAAGTGGACC CTGCCGGCCA CTCCTACATC 
CTTGTCACCT GCCTGGGCCT CTCCTATGAT GGCCTGCTGG GTGATGATCA GAGTACGCCC 
AAGACCGGCC TCCTGATAAT CGTCCTGGGC ATGATCTTAA TGGAGGGCAG CCGCGCCCCG 
GAGGAGGCAA TCTGGGAAGC GTTGAGTGTG ATGGGGCTGT ATGATGGGAG GGAGCACAGT 
GTCTATTGGA AGCTCAGGAA GCTGCTCACC CAAGAGTGGG TGCAGGAGAA CTACCTGGAG 
TACCGCCAGG CGCCCGGCAG TGATCCTGTG CGCTACGAGT TCCTGTGGGG TCCAAGGGCC 
CTTGCTGAAA CCAGCTATGT GAAAGTCCTG GAGCATGTGG TCAGGGTCAA TGCAAGAGTT 
CGCATTTCCT ACCCATCCCT GCATGAAGAG GCTTTGGGAG AGGAGAAAGG AGTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAGEA8 ( NM_001166401.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001159873.1 Homo sapiens MAGE family member A8 (MAGEA8), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu12673
Clone ID Related Accession (Same CDS sequence)	NM_001166400.1 , XM_017029520.1 , NM_005364.4 , NM_005364.5 , NM_001166401.1
Accession Version	NM_001166401.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 957bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Homo sapiens(human)
Product	melanoma-associated antigen 8
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK313943.1, BI092675.1, BC002455.2 and AA045817.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 all encode the same protein. ##Evidence-Data-START## Transcript exon combination :: BI092675.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142853, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTTCTTG GGCAGAAGAG TCAGCGCTAC AAGGCTGAGG AAGGCCTTCA GGCCCAAGGA 
GAGGCACCAG GGCTTATGGA TGTGCAGATT CCCACAGCTG AGGAGCAGAA GGCTGCATCC 
TCCTCCTCTA CTCTGATCAT GGGAACCCTT GAGGAGGTGA CTGATTCTGG GTCACCAAGT 
CCTCCCCAGA GTCCTGAGGG TGCCTCCTCT TCCCTGACTG TCACCGACAG CACTCTGTGG 
AGCCAATCCG ATGAGGGTTC CAGCAGCAAT GAAGAGGAGG GGCCAAGCAC CTCCCCGGAC 
CCAGCTCACC TGGAGTCCCT GTTCCGGGAA GCACTTGATG AGAAAGTGGC TGAGTTAGTT 
CGTTTCCTGC TCCGCAAATA TCAAATTAAG GAGCCGGTCA CAAAGGCAGA AATGCTTGAG 
AGTGTCATCA AAAATTACAA GAACCACTTT CCTGATATCT TCAGCAAAGC CTCTGAGTGC 
ATGCAGGTGA TCTTTGGCAT TGATGTGAAG GAAGTGGACC CTGCCGGCCA CTCCTACATC 
CTTGTCACCT GCCTGGGCCT CTCCTATGAT GGCCTGCTGG GTGATGATCA GAGTACGCCC 
AAGACCGGCC TCCTGATAAT CGTCCTGGGC ATGATCTTAA TGGAGGGCAG CCGCGCCCCG 
GAGGAGGCAA TCTGGGAAGC GTTGAGTGTG ATGGGGCTGT ATGATGGGAG GGAGCACAGT 
GTCTATTGGA AGCTCAGGAA GCTGCTCACC CAAGAGTGGG TGCAGGAGAA CTACCTGGAG 
TACCGCCAGG CGCCCGGCAG TGATCCTGTG CGCTACGAGT TCCTGTGGGG TCCAAGGGCC 
CTTGCTGAAA CCAGCTATGT GAAAGTCCTG GAGCATGTGG TCAGGGTCAA TGCAAGAGTT 
CGCATTTCCT ACCCATCCCT GCATGAAGAG GCTTTGGGAG AGGAGAAAGG AGTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001159873.1
CDS	522..1478
Translation	MLLGQKSQRYKAEEGLQAQGEAPGLMDVQIPTAEEQKAASSSSTLIMGTLEEVTDSGSPSPPQSPEGASSSLTVTDSTLWSQSDEGSSSNEEEGPSTSPDPAHLESLFREALDEKVAELVRFLLRKYQIKEPVTKAEMLESVIKNYKNHFPDIFSKASECMQVIFGIDVKEVDPAGHSYILVTCLGLSYDGLLGDDQSTPKTGLLIIVLGMILMEGSRAPEEAIWEALSVMGLYDGREHSVYWKLRKLLTQEWVQENYLEYRQAPGSDPVRYEFLWGPRALAETSYVKVLEHVVRVNARVRISYPSLHEEALGEEKGV

Target ORF information:

RefSeq Version	NM_001166401.1
Organism	Homo sapiens(human)
Definition	Homo sapiens MAGE family member A8 (MAGEA8), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001166401.1

ORF Insert Sequence:

ATGCTTCTTG GGCAGAAGAG TCAGCGCTAC AAGGCTGAGG AAGGCCTTCA GGCCCAAGGA 
GAGGCACCAG GGCTTATGGA TGTGCAGATT CCCACAGCTG AGGAGCAGAA GGCTGCATCC 
TCCTCCTCTA CTCTGATCAT GGGAACCCTT GAGGAGGTGA CTGATTCTGG GTCACCAAGT 
CCTCCCCAGA GTCCTGAGGG TGCCTCCTCT TCCCTGACTG TCACCGACAG CACTCTGTGG 
AGCCAATCCG ATGAGGGTTC CAGCAGCAAT GAAGAGGAGG GGCCAAGCAC CTCCCCGGAC 
CCAGCTCACC TGGAGTCCCT GTTCCGGGAA GCACTTGATG AGAAAGTGGC TGAGTTAGTT 
CGTTTCCTGC TCCGCAAATA TCAAATTAAG GAGCCGGTCA CAAAGGCAGA AATGCTTGAG 
AGTGTCATCA AAAATTACAA GAACCACTTT CCTGATATCT TCAGCAAAGC CTCTGAGTGC 
ATGCAGGTGA TCTTTGGCAT TGATGTGAAG GAAGTGGACC CTGCCGGCCA CTCCTACATC 
CTTGTCACCT GCCTGGGCCT CTCCTATGAT GGCCTGCTGG GTGATGATCA GAGTACGCCC 
AAGACCGGCC TCCTGATAAT CGTCCTGGGC ATGATCTTAA TGGAGGGCAG CCGCGCCCCG 
GAGGAGGCAA TCTGGGAAGC GTTGAGTGTG ATGGGGCTGT ATGATGGGAG GGAGCACAGT 
GTCTATTGGA AGCTCAGGAA GCTGCTCACC CAAGAGTGGG TGCAGGAGAA CTACCTGGAG 
TACCGCCAGG CGCCCGGCAG TGATCCTGTG CGCTACGAGT TCCTGTGGGG TCCAAGGGCC 
CTTGCTGAAA CCAGCTATGT GAAAGTCCTG GAGCATGTGG TCAGGGTCAA TGCAAGAGTT 
CGCATTTCCT ACCCATCCCT GCATGAAGAG GCTTTGGGAG AGGAGAAAGG AGTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAGEA8 ( XM_017029520.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016885009.1 Homo sapiens MAGE family member A8 (MAGEA8), transcript variant X1, mRNA.

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CloneID	OHu12673
Clone ID Related Accession (Same CDS sequence)	NM_001166400.1 , XM_017029520.1 , NM_005364.4 , NM_005364.5 , NM_001166401.1
Accession Version	XM_017029520.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 957bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	melanoma-associated antigen 8 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTTCTTG GGCAGAAGAG TCAGCGCTAC AAGGCTGAGG AAGGCCTTCA GGCCCAAGGA 
GAGGCACCAG GGCTTATGGA TGTGCAGATT CCCACAGCTG AGGAGCAGAA GGCTGCATCC 
TCCTCCTCTA CTCTGATCAT GGGAACCCTT GAGGAGGTGA CTGATTCTGG GTCACCAAGT 
CCTCCCCAGA GTCCTGAGGG TGCCTCCTCT TCCCTGACTG TCACCGACAG CACTCTGTGG 
AGCCAATCCG ATGAGGGTTC CAGCAGCAAT GAAGAGGAGG GGCCAAGCAC CTCCCCGGAC 
CCAGCTCACC TGGAGTCCCT GTTCCGGGAA GCACTTGATG AGAAAGTGGC TGAGTTAGTT 
CGTTTCCTGC TCCGCAAATA TCAAATTAAG GAGCCGGTCA CAAAGGCAGA AATGCTTGAG 
AGTGTCATCA AAAATTACAA GAACCACTTT CCTGATATCT TCAGCAAAGC CTCTGAGTGC 
ATGCAGGTGA TCTTTGGCAT TGATGTGAAG GAAGTGGACC CTGCCGGCCA CTCCTACATC 
CTTGTCACCT GCCTGGGCCT CTCCTATGAT GGCCTGCTGG GTGATGATCA GAGTACGCCC 
AAGACCGGCC TCCTGATAAT CGTCCTGGGC ATGATCTTAA TGGAGGGCAG CCGCGCCCCG 
GAGGAGGCAA TCTGGGAAGC GTTGAGTGTG ATGGGGCTGT ATGATGGGAG GGAGCACAGT 
GTCTATTGGA AGCTCAGGAA GCTGCTCACC CAAGAGTGGG TGCAGGAGAA CTACCTGGAG 
TACCGCCAGG CGCCCGGCAG TGATCCTGTG CGCTACGAGT TCCTGTGGGG TCCAAGGGCC 
CTTGCTGAAA CCAGCTATGT GAAAGTCCTG GAGCATGTGG TCAGGGTCAA TGCAAGAGTT 
CGCATTTCCT ACCCATCCCT GCATGAAGAG GCTTTGGGAG AGGAGAAAGG AGTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016885009.1
CDS	338..1294
Translation	MLLGQKSQRYKAEEGLQAQGEAPGLMDVQIPTAEEQKAASSSSTLIMGTLEEVTDSGSPSPPQSPEGASSSLTVTDSTLWSQSDEGSSSNEEEGPSTSPDPAHLESLFREALDEKVAELVRFLLRKYQIKEPVTKAEMLESVIKNYKNHFPDIFSKASECMQVIFGIDVKEVDPAGHSYILVTCLGLSYDGLLGDDQSTPKTGLLIIVLGMILMEGSRAPEEAIWEALSVMGLYDGREHSVYWKLRKLLTQEWVQENYLEYRQAPGSDPVRYEFLWGPRALAETSYVKVLEHVVRVNARVRISYPSLHEEALGEEKGV

Target ORF information:

RefSeq Version	XM_017029520.1
Organism	Homo sapiens(human)
Definition	Homo sapiens MAGE family member A8 (MAGEA8), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017029520.1

ORF Insert Sequence:

ATGCTTCTTG GGCAGAAGAG TCAGCGCTAC AAGGCTGAGG AAGGCCTTCA GGCCCAAGGA 
GAGGCACCAG GGCTTATGGA TGTGCAGATT CCCACAGCTG AGGAGCAGAA GGCTGCATCC 
TCCTCCTCTA CTCTGATCAT GGGAACCCTT GAGGAGGTGA CTGATTCTGG GTCACCAAGT 
CCTCCCCAGA GTCCTGAGGG TGCCTCCTCT TCCCTGACTG TCACCGACAG CACTCTGTGG 
AGCCAATCCG ATGAGGGTTC CAGCAGCAAT GAAGAGGAGG GGCCAAGCAC CTCCCCGGAC 
CCAGCTCACC TGGAGTCCCT GTTCCGGGAA GCACTTGATG AGAAAGTGGC TGAGTTAGTT 
CGTTTCCTGC TCCGCAAATA TCAAATTAAG GAGCCGGTCA CAAAGGCAGA AATGCTTGAG 
AGTGTCATCA AAAATTACAA GAACCACTTT CCTGATATCT TCAGCAAAGC CTCTGAGTGC 
ATGCAGGTGA TCTTTGGCAT TGATGTGAAG GAAGTGGACC CTGCCGGCCA CTCCTACATC 
CTTGTCACCT GCCTGGGCCT CTCCTATGAT GGCCTGCTGG GTGATGATCA GAGTACGCCC 
AAGACCGGCC TCCTGATAAT CGTCCTGGGC ATGATCTTAA TGGAGGGCAG CCGCGCCCCG 
GAGGAGGCAA TCTGGGAAGC GTTGAGTGTG ATGGGGCTGT ATGATGGGAG GGAGCACAGT 
GTCTATTGGA AGCTCAGGAA GCTGCTCACC CAAGAGTGGG TGCAGGAGAA CTACCTGGAG 
TACCGCCAGG CGCCCGGCAG TGATCCTGTG CGCTACGAGT TCCTGTGGGG TCCAAGGGCC 
CTTGCTGAAA CCAGCTATGT GAAAGTCCTG GAGCATGTGG TCAGGGTCAA TGCAAGAGTT 
CGCATTTCCT ACCCATCCCT GCATGAAGAG GCTTTGGGAG AGGAGAAAGG AGTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

An inter-species protein-protein interaction network across vast evolutionary distance.
Molecular systems biology12(4)865(2016 Apr)
Zhong Q,Pevzner SJ,Hao T,Wang Y,Mosca R,Menche J,Taipale M,Ta?an M,Fan C,Yang X,Haley P,Murray RR,Mer F,Gebreab F,Tam S,MacWilliams A,Dricot A,Reichert P,Santhanam B,Ghamsari L,Calderwood MA,Rolland T,Charloteaux B,Lindquist S,Barab?si AL,Hill DE,Aloy P,Cusick ME,Xia Y,Roth FP,Vidal M

Widespread macromolecular interaction perturbations in human genetic disorders.
Cell161(3)647-660(2015 Apr)
Sahni N,Yi S,Taipale M,Fuxman Bass JI,Coulombe-Huntington J,Yang F,Peng J,Weile J,Karras GI,Wang Y,Kov?cs IA,Kamburov A,Krykbaeva I,Lam MH,Tucker G,Khurana V,Sharma A,Liu YY,Yachie N,Zhong Q,Shen Y,Palagi A,San-Miguel A,Fan C,Balcha D,Dricot A,Jordan DM,Walsh JM,Shah AA,Yang X,Stoyanova AK,Leighton A,Calderwood MA,Jacob Y,Cusick ME,Salehi-Ashtiani K,Whitesell LJ,Sunyaev S,Berger B,Barab?si AL,Charloteaux B,Hill DE,Hao T,Roth FP,Xia Y,Walhout AJM,Lindquist S,Vidal M

Quantitative evaluation of the expression of MAGE genes in tumors by limiting dilution of cDNA libraries.
International journal of cancer83(5)664-9(1999 Nov)
Serrano A,Leth? B,Delroisse JM,Lurquin C,De Plaen E,Brasseur F,Rimoldi D,Boon T

The melanoma antigen gene (MAGE) family is clustered in the chromosomal band Xq28.
Genomics29(3)725-31(1995 Oct)
Rogner UC,Wilke K,Steck E,Korn B,Poustka A

Structure, chromosomal localization, and expression of 12 genes of the MAGE family.
Immunogenetics40(5)360-9(1994)
De Plaen E,Arden K,Traversari C,Gaforio JJ,Szikora JP,De Smet C,Brasseur F,van der Bruggen P,Leth? B,Lurquin C

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MAGEA8 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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