LRP4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	LRP4
Entrez Gene ID	4038
Full Name	LDL receptor related protein 4
Synonyms	CLSS,CMS17,LRP-4,LRP10,MEGF7,SOST2
General protein information	Preferred Names LDL receptor related protein 4 Names low-density lipoprotein receptor-related protein 4 multiple epidermal growth factor-like domains 7
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11p11.2
Summary	This gene encodes a member of the low-density lipoprotein receptor-related protein family. The encoded protein may be a regulator of Wnt signaling. Mutations in this gene are associated with Cenani-Lenz syndrome. [provided by RefSeq, May 2010].
Disorder MIM:	604270
Disorder Html:	Cenani-Lenz syndactyly syndrome, 212780 (3); Sclerosteosis 2, 614305 (3); ?Myasthenic syndrome, congenital, 17, 616304 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_002334.3	NP_002325.2	low-density lipoprotein receptor-related protein 4 precursor
XM_011520103.2	XP_011518405.1	low-density lipoprotein receptor-related protein 4 isoform X2
XM_011520102.1	XP_011518404.1	low-density lipoprotein receptor-related protein 4 isoform X1
XM_017017734.1	XP_016873223.1	low-density lipoprotein receptor-related protein 4 isoform X1
XM_011520104.2	XP_011518406.1	low-density lipoprotein receptor-related protein 4 isoform X3
NM_002334.4	NP_002325.2	low-density lipoprotein receptor-related protein 4 precursor

Pathways from BioSystems

Homologies

	LRP4	XP_001111133.2
Mus musculus (house mouse)	Lrp4	NP_766256.3
Rattus norvegicus (Norway rat)	Lrp4	NP_112612.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000037	XP_311125.5
Pan troglodytes (chimpanzee)	LRP4	XP_508403.4
Danio rerio (zebrafish)	lrp4	XP_005169124.1
Gallus gallus (chicken)	LRP4	XP_421114.4
Drosophila melanogaster (fruit fly)	CG8909	NP_001162769.1
Xenopus tropicalis (tropical clawed frog)	lrp4	XP_002941898.2
Homo sapiens (human)	LRP4	NP_002325.2
Canis lupus familiaris (dog)	LRP4	XP_005631328.1
Bos taurus (cattle)	LRP4	NP_001071311.1

Gene Ontology
Bibliography

Related articles in PubMed

Novel splice mutation in LRP4 causes severe type of Cenani-Lenz syndactyly syndrome with oro-facial and skeletal symptoms.
Afzal M, Zaman Q, Kornak U, Mundlos S, Malik S, Fl?ttmann R
European journal of medical genetics60(8)421-425(2017 Aug)

Exome sequencing of two Italian pedigrees with non-isolated Chiari malformation type I reveals candidate genes for cranio-facial development.
Merello E, Tattini L, Magi A, Accogli A, Piatelli G, Pavanello M, Tortora D, Cama A, Kibar Z, Capra V, De Marco P
European journal of human genetics : EJHG25(8)952-959(2017 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

A novel splice variant in LRP4 (c.316+1G > A) segregated with Cenani-Lenz syndactyly phenotype in a five generations family.
Title: Novel splice mutation in LRP4 causes severe type of Cenani-Lenz syndactyly syndrome with oro-facial and skeletal symptoms.

LRP4 c.2552C>G (p.(T851R) variant was identified in the family with Chiari malformation type 1.
Title: Exome sequencing of two Italian pedigrees with non-isolated Chiari malformation type I reveals candidate genes for cranio-facial development.

the first evidence suggesting that LRP4 is responsible for the retention of sclerostin in the bone environment in humans.
Title: A Novel Domain-Specific Mutation in a Sclerosteosis Patient Suggests a Role of LRP4 as an Anchor for Sclerostin in Human Bone.

LRP4 is essential for maintaining the structural and functional activity of the neuromuscular junction.
Title: LRP4 is critical for neuromuscular junction maintenance.

study presents 2 sibling fetuses with a prenatal lethal presentation of mesomelic limb reductions, oligosyndactyly, genitourinary malformation and compound heterozygosity for 2 novel truncating mutations in LRP4
Title: Truncating mutations in LRP4 lead to a prenatal lethal form of Cenani-Lenz syndrome.

The following LRP4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LRP4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu25180	NM_002334.4 Latest version!	Homo sapiens LDL receptor related protein 4 (LRP4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$679.50-$951.30 $1359.00
OHu58774	XM_011520102.1 Latest version!	Homo sapiens low density lipoprotein receptor-related protein 4 (LRP4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$951.30 $1359.00
OHu58775	XM_011520103.2 Latest version!	Homo sapiens LDL receptor related protein 4 (LRP4), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$811.30 $1159.00
OHu58776	XM_011520104.2 Latest version!	Homo sapiens LDL receptor related protein 4 (LRP4), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$559.30 $799.00
OHu92227	XM_017017734.1 Latest version!	Homo sapiens LDL receptor related protein 4 (LRP4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$951.30 $1359.00
View Old Accession Versions >>
OHu25180	NM_002334.3	Homo sapiens LDL receptor related protein 4 (LRP4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$679.50-$951.30 $1359.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LRP4 ( NM_002334.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002325.2 Homo sapiens LDL receptor related protein 4 (LRP4), mRNA.

Price & Availability↑

CloneID	OHu25180
Clone ID Related Accession (Same CDS sequence)	NM_002334.3 , NM_002334.4
Accession Version	NM_002334.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5718bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-17
Organism	Homo sapiens(human)
Product	low-density lipoprotein receptor-related protein 4 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB084910.1, AC021573.10 and BQ446811.1. This sequence is a reference standard in the RefSeqGene project. On May 27, 2010 this sequence version replaced NM_002334.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB084910.1, AB231861.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGAGGCGGC AGTGGGGCGC GCTGCTGCTT GGCGCCCTGC TCTGCGCACA CGGCCTGGCC 
AGCAGCCCCG AGTGTGCTTG TGGTCGGAGC CACTTCACAT GTGCAGTGAG TGCTCTTGGA 
GAGTGTACCT GCATCCCTGC CCAGTGGCAG TGTGATGGAG ACAATGACTG CGGGGACCAC 
AGCGATGAGG ATGGATGTAT ACTACCTACC TGTTCCCCTC TTGACTTTCA CTGTGACAAT 
GGCAAGTGCA TCCGCCGCTC CTGGGTGTGT GACGGGGACA ACGACTGTGA GGATGACTCG 
GATGAGCAGG ACTGTCCCCC CCGGGAGTGT GAGGAGGACG AGTTTCCCTG CCAGAATGGC 
TACTGCATCC GGAGTCTGTG GCACTGCGAT GGTGACAATG ACTGTGGCGA CAACAGCGAT 
GAGCAGTGTG ACATGCGCAA GTGCTCCGAC AAGGAGTTCC GCTGTAGTGA CGGAAGCTGC 
ATTGCTGAGC ATTGGTACTG CGACGGTGAC ACCGACTGCA AAGATGGCTC CGATGAGGAG 
AACTGTCCCT CAGCAGTGCC AGCGCCCCCC TGCAACCTGG AGGAGTTCCA GTGTGCCTAT 
GGACGCTGCA TCCTCGACAT CTACCACTGC GATGGCGACG ATGACTGTGG AGACTGGTCA 
GACGAGTCTG ACTGCTCCTC CCACCAGCCC TGCCGCTCTG GGGAGTTCAT GTGTGACAGT 
GGCCTGTGCA TCAATGCAGG CTGGCGCTGC GATGGTGACG CGGACTGTGA TGACCAGTCT 
GATGAGCGCA ACTGCACCAC CTCCATGTGT ACGGCAGAAC AGTTCCGCTG TCACTCAGGC 
CGCTGTGTCC GCCTGTCCTG GCGCTGTGAT GGGGAGGACG ACTGTGCAGA CAACAGCGAT 
GAAGAGAACT GTGAGAATAC AGGAAGCCCC CAATGTGCCT TGGACCAGTT CCTGTGTTGG 
AATGGGCGCT GCATTGGGCA GAGGAAGCTG TGCAACGGGG TCAACGACTG TGGTGACAAC 
AGCGACGAAA GCCCACAGCA GAATTGCCGG CCCCGGACGG GTGAGGAGAA CTGCAATGTT 
AACAACGGTG GCTGTGCCCA GAAGTGCCAG ATGGTGCGGG GGGCAGTGCA GTGTACCTGC 
CACACAGGCT ACCGGCTCAC AGAGGATGGG CACACGTGCC AAGATGTGAA TGAATGTGCC 
GAGGAGGGGT ATTGCAGCCA GGGCTGCACC AACAGCGAAG GGGCTTTCCA ATGCTGGTGT 
GAAACAGGCT ATGAACTACG GCCCGACCGG CGCAGCTGCA AGGCTCTGGG GCCAGAGCCT 
GTGCTGCTGT TCGCCAATCG CATCGACATC CGGCAGGTGC TGCCACACCG CTCTGAGTAC 
ACACTGCTGC TTAACAACCT GGAGAATGCC ATTGCCCTTG ATTTCCACCA CCGCCGCGAG 
CTTGTCTTCT GGTCAGATGT CACCCTGGAC CGGATCCTCC GTGCCAACCT CAACGGCAGC 
AACGTGGAGG AGGTTGTGTC TACTGGGCTG GAGAGCCCAG GGGGCCTGGC TGTGGATTGG 
GTCCATGACA AACTCTACTG GACCGACTCA GGCACCTCGA GGATTGAGGT GGCCAATCTG 
GATGGGGCCC ACCGGAAAGT GTTGCTGTGG CAGAACCTGG AGAAGCCCCG GGCCATTGCC 
TTGCATCCCA TGGAGGGTAC CATTTACTGG ACAGACTGGG GCAACACCCC CCGTATTGAG 
GCCTCCAGCA TGGATGGCTC TGGACGCCGC ATCATTGCCG ATACCCATCT CTTCTGGCCC 
AATGGCCTCA CCATCGACTA TGCCGGGCGC CGTATGTACT GGGTGGATGC TAAGCACCAT 
GTCATCGAGA GGGCCAATCT GGATGGGAGT CACCGTAAGG CTGTCATTAG CCAGGGCCTC 
CCGCATCCCT TCGCCATCAC AGTGTTTGAA GACAGCCTGT ACTGGACAGA CTGGCACACC 
AAGAGCATCA ATAGCGCTAA CAAATTTACG GGGAAGAACC AGGAAATCAT TCGCAACAAA 
CTCCACTTCC CTATGGACAT CCACACCTTG CACCCCCAGC GCCAACCTGC AGGGAAAAAC 
CGCTGTGGGG ACAACAACGG AGGCTGCACG CACCTGTGTC TGCCCAGTGG CCAGAACTAC 
ACCTGTGCCT GCCCCACTGG CTTCCGCAAG ATCAGCAGCC ACGCCTGTGC CCAGAGTCTT 
GACAAGTTCC TGCTTTTTGC CCGAAGGATG GACATCCGTC GAATCAGCTT TGACACAGAG 
GACCTGTCTG ATGATGTCAT CCCACTGGCT GACGTGCGCA GTGCTGTGGC CCTTGACTGG 
GACTCCCGGG ATGACCACGT GTACTGGACA GATGTCAGCA CTGATACCAT CAGCAGGGCC 
AAGTGGGATG GAACAGGACA GGAGGTGGTA GTGGATACCA GTTTGGAGAG CCCAGCTGGC 
CTGGCCATTG ATTGGGTCAC CAACAAACTG TACTGGACAG ATGCAGGTAC AGACCGGATT 
GAAGTAGCCA ACACAGATGG CAGCATGAGA ACAGTACTCA TCTGGGAGAA CCTTGATCGT 
CCTCGGGACA TCGTGGTGGA ACCCATGGGC GGGTACATGT ATTGGACTGA CTGGGGTGCG 
AGCCCCAAGA TTGAACGAGC TGGCATGGAT GCCTCAGGCC GCCAAGTCAT TATCTCTTCT 
AATCTGACCT GGCCTAATGG GTTAGCTATT GATTATGGGT CCCAGCGTCT ATACTGGGCT 
GACGCCGGCA TGAAGACAAT TGAATTTGCT GGACTGGATG GCAGTAAGAG GAAGGTGCTG 
ATTGGAAGCC AGCTCCCCCA CCCATTTGGG CTGACCCTCT ATGGAGAGCG CATCTATTGG 
ACTGACTGGC AGACCAAGAG CATACAGAGC GCTGACCGGC TGACAGGGCT GGACCGGGAG 
ACTCTGCAGG AGAACCTGGA AAACCTAATG GACATCCATG TCTTCCACCG CCGCCGGCCC 
CCAGTGTCTA CACCATGTGC TATGGAGAAT GGCGGCTGTA GCCACCTGTG TCTTAGGTCC 
CCAAATCCAA GCGGATTCAG CTGTACCTGC CCCACAGGCA TCAACCTGCT GTCTGATGGC 
AAGACCTGCT CACCAGGCAT GAACAGTTTC CTCATCTTCG CCAGGAGGAT AGACATTCGC 
ATGGTCTCCC TGGACATCCC TTATTTTGCT GATGTGGTGG TACCAATCAA CATTACCATG 
AAGAACACCA TTGCCATTGG AGTAGACCCC CAGGAAGGAA AGGTGTACTG GTCTGACAGC 
ACACTGCACA GGATCAGTCG TGCCAATCTG GATGGCTCAC AGCATGAGGA CATCATCACC 
ACAGGGCTAC AGACCACAGA TGGGCTCGCG GTTGATGCCA TTGGCCGGAA AGTATACTGG 
ACAGACACGG GAACAAACCG GATTGAAGTG GGCAACCTGG ACGGGTCCAT GCGGAAAGTG 
TTGGTGTGGC AGAACCTTGA CAGTCCCCGG GCCATCGTAC TGTACCATGA GATGGGGTTT 
ATGTACTGGA CAGACTGGGG GGAGAATGCC AAGTTAGAGC GGTCCGGAAT GGATGGCTCA 
GACCGCGCGG TGCTCATCAA CAACAACCTA GGATGGCCCA ATGGACTGAC TGTGGACAAG 
GCCAGCTCCC AACTGCTATG GGCCGATGCC CACACCGAGC GAATTGAGGC TGCTGACCTG 
AATGGTGCCA ATCGGCATAC ATTGGTGTCA CCGGTGCAGC ACCCATATGG CCTCACCCTG 
CTCGACTCCT ATATCTACTG GACTGACTGG CAGACTCGGA GCATCCACCG TGCTGACAAG 
GGTACTGGCA GCAATGTCAT CCTCGTGAGG TCCAACCTGC CAGGCCTCAT GGACATGCAG 
GCTGTGGACC GGGCACAGCC ACTAGGTTTT AACAAGTGCG GCTCGAGAAA TGGCGGCTGC 
TCCCACCTCT GCTTGCCTCG GCCTTCTGGC TTCTCCTGTG CCTGCCCCAC TGGCATCCAG 
CTGAAGGGAG ATGGGAAGAC CTGTGATCCC TCTCCTGAGA CCTACCTGCT CTTCTCCAGC 
CGTGGCTCCA TCCGGCGTAT CTCACTGGAC ACCAGTGACC ACACCGATGT GCATGTCCCT 
GTTCCTGAGC TCAACAATGT CATCTCCCTG GACTATGACA GCGTGGATGG AAAGGTCTAT 
TACACAGATG TGTTCCTGGA TGTTATCAGG CGAGCAGACC TGAACGGCAG CAACATGGAG 
ACAGTGATCG GGCGAGGGCT GAAGACCACT GACGGGCTGG CAGTGGACTG GGTGGCCAGG 
AACCTGTACT GGACAGACAC AGGTCGAAAT ACCATTGAGG CGTCCAGGCT GGATGGTTCC 
TGCCGCAAAG TACTGATCAA CAATAGCCTG GATGAGCCCC GGGCCATTGC TGTTTTCCCC 
AGGAAGGGGT ACCTCTTCTG GACAGACTGG GGCCACATTG CCAAGATCGA ACGGGCAAAC 
TTGGATGGTT CTGAGCGGAA GGTCCTCATC AACACAGACC TGGGTTGGCC CAATGGCCTT 
ACCCTGGACT ATGATACCCG CAGGATCTAC TGGGTGGATG CGCATCTGGA CCGGATCGAG 
AGTGCTGACC TCAATGGGAA ACTGCGGCAG GTCTTGGTCA GCCATGTGTC CCACCCCTTT 
GCCCTCACAC AGCAAGACAG GTGGATCTAC TGGACAGACT GGCAGACCAA GTCAATCCAG 
CGTGTTGACA AATACTCAGG CCGGAACAAG GAGACAGTGC TGGCAAATGT GGAAGGACTC 
ATGGATATCA TCGTGGTTTC CCCTCAGCGG CAGACAGGGA CCAATGCCTG TGGTGTGAAC 
AATGGTGGCT GCACCCACCT CTGCTTTGCC AGAGCCTCGG ACTTCGTATG TGCCTGTCCT 
GACGAACCTG ATAGCCGGCC CTGCTCCCTT GTGCCTGGCC TGGTACCACC AGCTCCTAGG 
GCTACTGGCA TGAGTGAAAA GAGCCCAGTG CTACCCAACA CACCACCTAC CACCTTGTAT 
TCTTCAACCA CCCGGACCCG CACGTCTCTG GAGGAGGTGG AAGGAAGATG CTCTGAAAGG 
GATGCCAGGC TGGGCCTCTG TGCACGTTCC AATGACGCTG TTCCTGCTGC TCCAGGGGAA 
GGACTTCATA TCAGCTACGC CATTGGTGGA CTCCTCAGTA TTCTGCTGAT TTTGGTGGTG 
ATTGCAGCTT TGATGCTGTA CAGACACAAA AAATCCAAGT TCACTGATCC TGGAATGGGG 
AACCTCACCT ACAGCAACCC CTCCTACCGA ACATCCACAC AGGAAGTGAA GATTGAAGCA 
ATCCCCAAAC CAGCCATGTA CAACCAGCTG TGCTATAAGA AAGAGGGAGG GCCTGACCAT 
AACTACACCA AGGAGAAGAT CAAGATCGTA GAGGGAATCT GCCTCCTGTC TGGGGATGAT 
GCTGAGTGGG ATGACCTCAA GCAACTGCGA AGCTCACGGG GGGGCCTCCT CCGGGATCAT 
GTATGCATGA AGACAGACAC GGTGTCCATC CAGGCCAGCT CTGGCTCCCT GGATGACACA 
GAGACGGAGC AGCTGTTACA GGAAGAGCAG TCTGAGTGTA GCAGCGTCCA TACTGCAGCC 
ACTCCAGAAA GACGAGGCTC TCTGCCAGAC ACGGGCTGGA AACATGAACG CAAGCTCTCC 
TCAGAGAGCC AGGTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002325.2
CDS	244..5961
Translation	MRRQWGALLLGALLCAHGLASSPECACGRSHFTCAVSALGECTCIPAQWQCDGDNDCGDHSDEDGCILPTCSPLDFHCDNGKCIRRSWVCDGDNDCEDDSDEQDCPPRECEEDEFPCQNGYCIRSLWHCDGDNDCGDNSDEQCDMRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEENCPSAVPAPPCNLEEFQCAYGRCILDIYHCDGDDDCGDWSDESDCSSHQPCRSGEFMCDSGLCINAGWRCDGDADCDDQSDERNCTTSMCTAEQFRCHSGRCVRLSWRCDGEDDCADNSDEENCENTGSPQCALDQFLCWNGRCIGQRKLCNGVNDCGDNSDESPQQNCRPRTGEENCNVNNGGCAQKCQMVRGAVQCTCHTGYRLTEDGHTCQDVNECAEEGYCSQGCTNSEGAFQCWCETGYELRPDRRSCKALGPEPVLLFANRIDIRQVLPHRSEYTLLLNNLENAIALDFHHRRELVFWSDVTLDRILRANLNGSNVEEVVSTGLESPGGLAVDWVHDKLYWTDSGTSRIEVANLDGAHRKVLLWQNLEKPRAIALHPMEGTIYWTDWGNTPRIEASSMDGSGRRIIADTHLFWPNGLTIDYAGRRMYWVDAKHHVIERANLDGSHRKAVISQGLPHPFAITVFEDSLYWTDWHTKSINSANKFTGKNQEIIRNKLHFPMDIHTLHPQRQPAGKNRCGDNNGGCTHLCLPSGQNYTCACPTGFRKISSHACAQSLDKFLLFARRMDIRRISFDTEDLSDDVIPLADVRSAVALDWDSRDDHVYWTDVSTDTISRAKWDGTGQEVVVDTSLESPAGLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWENLDRPRDIVVEPMGGYMYWTDWGASPKIERAGMDASGRQVIISSNLTWPNGLAIDYGSQRLYWADAGMKTIEFAGLDGSKRKVLIGSQLPHPFGLTLYGERIYWTDWQTKSIQSADRLTGLDRETLQENLENLMDIHVFHRRRPPVSTPCAMENGGCSHLCLRSPNPSGFSCTCPTGINLLSDGKTCSPGMNSFLIFARRIDIRMVSLDIPYFADVVVPINITMKNTIAIGVDPQEGKVYWSDSTLHRISRANLDGSQHEDIITTGLQTTDGLAVDAIGRKVYWTDTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIVLYHEMGFMYWTDWGENAKLERSGMDGSDRAVLINNNLGWPNGLTVDKASSQLLWADAHTERIEAADLNGANRHTLVSPVQHPYGLTLLDSYIYWTDWQTRSIHRADKGTGSNVILVRSNLPGLMDMQAVDRAQPLGFNKCGSRNGGCSHLCLPRPSGFSCACPTGIQLKGDGKTCDPSPETYLLFSSRGSIRRISLDTSDHTDVHVPVPELNNVISLDYDSVDGKVYYTDVFLDVIRRADLNGSNMETVIGRGLKTTDGLAVDWVARNLYWTDTGRNTIEASRLDGSCRKVLINNSLDEPRAIAVFPRKGYLFWTDWGHIAKIERANLDGSERKVLINTDLGWPNGLTLDYDTRRIYWVDAHLDRIESADLNGKLRQVLVSHVSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGRNKETVLANVEGLMDIIVVSPQRQTGTNACGVNNGGCTHLCFARASDFVCACPDEPDSRPCSLVPGLVPPAPRATGMSEKSPVLPNTPPTTLYSSTTRTRTSLEEVEGRCSERDARLGLCARSNDAVPAAPGEGLHISYAIGGLLSILLILVVIAALMLYRHKKSKFTDPGMGNLTYSNPSYRTSTQEVKIEAIPKPAMYNQLCYKKEGGPDHNYTKEKIKIVEGICLLSGDDAEWDDLKQLRSSRGGLLRDHVCMKTDTVSIQASSGSLDDTETEQLLQEEQSECSSVHTAATPERRGSLPDTGWKHERKLSSESQV

Target ORF information:

RefSeq Version	NM_002334.3
Organism	Homo sapiens(human)
Definition	Homo sapiens LDL receptor related protein 4 (LRP4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002334.3

ORF Insert Sequence:

ATGAGGCGGC AGTGGGGCGC GCTGCTGCTT GGCGCCCTGC TCTGCGCACA CGGCCTGGCC 
AGCAGCCCCG AGTGTGCTTG TGGTCGGAGC CACTTCACAT GTGCAGTGAG TGCTCTTGGA 
GAGTGTACCT GCATCCCTGC CCAGTGGCAG TGTGATGGAG ACAATGACTG CGGGGACCAC 
AGCGATGAGG ATGGATGTAT ACTACCTACC TGTTCCCCTC TTGACTTTCA CTGTGACAAT 
GGCAAGTGCA TCCGCCGCTC CTGGGTGTGT GACGGGGACA ACGACTGTGA GGATGACTCG 
GATGAGCAGG ACTGTCCCCC CCGGGAGTGT GAGGAGGACG AGTTTCCCTG CCAGAATGGC 
TACTGCATCC GGAGTCTGTG GCACTGCGAT GGTGACAATG ACTGTGGCGA CAACAGCGAT 
GAGCAGTGTG ACATGCGCAA GTGCTCCGAC AAGGAGTTCC GCTGTAGTGA CGGAAGCTGC 
ATTGCTGAGC ATTGGTACTG CGACGGTGAC ACCGACTGCA AAGATGGCTC CGATGAGGAG 
AACTGTCCCT CAGCAGTGCC AGCGCCCCCC TGCAACCTGG AGGAGTTCCA GTGTGCCTAT 
GGACGCTGCA TCCTCGACAT CTACCACTGC GATGGCGACG ATGACTGTGG AGACTGGTCA 
GACGAGTCTG ACTGCTCCTC CCACCAGCCC TGCCGCTCTG GGGAGTTCAT GTGTGACAGT 
GGCCTGTGCA TCAATGCAGG CTGGCGCTGC GATGGTGACG CGGACTGTGA TGACCAGTCT 
GATGAGCGCA ACTGCACCAC CTCCATGTGT ACGGCAGAAC AGTTCCGCTG TCACTCAGGC 
CGCTGTGTCC GCCTGTCCTG GCGCTGTGAT GGGGAGGACG ACTGTGCAGA CAACAGCGAT 
GAAGAGAACT GTGAGAATAC AGGAAGCCCC CAATGTGCCT TGGACCAGTT CCTGTGTTGG 
AATGGGCGCT GCATTGGGCA GAGGAAGCTG TGCAACGGGG TCAACGACTG TGGTGACAAC 
AGCGACGAAA GCCCACAGCA GAATTGCCGG CCCCGGACGG GTGAGGAGAA CTGCAATGTT 
AACAACGGTG GCTGTGCCCA GAAGTGCCAG ATGGTGCGGG GGGCAGTGCA GTGTACCTGC 
CACACAGGCT ACCGGCTCAC AGAGGATGGG CACACGTGCC AAGATGTGAA TGAATGTGCC 
GAGGAGGGGT ATTGCAGCCA GGGCTGCACC AACAGCGAAG GGGCTTTCCA ATGCTGGTGT 
GAAACAGGCT ATGAACTACG GCCCGACCGG CGCAGCTGCA AGGCTCTGGG GCCAGAGCCT 
GTGCTGCTGT TCGCCAATCG CATCGACATC CGGCAGGTGC TGCCACACCG CTCTGAGTAC 
ACACTGCTGC TTAACAACCT GGAGAATGCC ATTGCCCTTG ATTTCCACCA CCGCCGCGAG 
CTTGTCTTCT GGTCAGATGT CACCCTGGAC CGGATCCTCC GTGCCAACCT CAACGGCAGC 
AACGTGGAGG AGGTTGTGTC TACTGGGCTG GAGAGCCCAG GGGGCCTGGC TGTGGATTGG 
GTCCATGACA AACTCTACTG GACCGACTCA GGCACCTCGA GGATTGAGGT GGCCAATCTG 
GATGGGGCCC ACCGGAAAGT GTTGCTGTGG CAGAACCTGG AGAAGCCCCG GGCCATTGCC 
TTGCATCCCA TGGAGGGTAC CATTTACTGG ACAGACTGGG GCAACACCCC CCGTATTGAG 
GCCTCCAGCA TGGATGGCTC TGGACGCCGC ATCATTGCCG ATACCCATCT CTTCTGGCCC 
AATGGCCTCA CCATCGACTA TGCCGGGCGC CGTATGTACT GGGTGGATGC TAAGCACCAT 
GTCATCGAGA GGGCCAATCT GGATGGGAGT CACCGTAAGG CTGTCATTAG CCAGGGCCTC 
CCGCATCCCT TCGCCATCAC AGTGTTTGAA GACAGCCTGT ACTGGACAGA CTGGCACACC 
AAGAGCATCA ATAGCGCTAA CAAATTTACG GGGAAGAACC AGGAAATCAT TCGCAACAAA 
CTCCACTTCC CTATGGACAT CCACACCTTG CACCCCCAGC GCCAACCTGC AGGGAAAAAC 
CGCTGTGGGG ACAACAACGG AGGCTGCACG CACCTGTGTC TGCCCAGTGG CCAGAACTAC 
ACCTGTGCCT GCCCCACTGG CTTCCGCAAG ATCAGCAGCC ACGCCTGTGC CCAGAGTCTT 
GACAAGTTCC TGCTTTTTGC CCGAAGGATG GACATCCGTC GAATCAGCTT TGACACAGAG 
GACCTGTCTG ATGATGTCAT CCCACTGGCT GACGTGCGCA GTGCTGTGGC CCTTGACTGG 
GACTCCCGGG ATGACCACGT GTACTGGACA GATGTCAGCA CTGATACCAT CAGCAGGGCC 
AAGTGGGATG GAACAGGACA GGAGGTGGTA GTGGATACCA GTTTGGAGAG CCCAGCTGGC 
CTGGCCATTG ATTGGGTCAC CAACAAACTG TACTGGACAG ATGCAGGTAC AGACCGGATT 
GAAGTAGCCA ACACAGATGG CAGCATGAGA ACAGTACTCA TCTGGGAGAA CCTTGATCGT 
CCTCGGGACA TCGTGGTGGA ACCCATGGGC GGGTACATGT ATTGGACTGA CTGGGGTGCG 
AGCCCCAAGA TTGAACGAGC TGGCATGGAT GCCTCAGGCC GCCAAGTCAT TATCTCTTCT 
AATCTGACCT GGCCTAATGG GTTAGCTATT GATTATGGGT CCCAGCGTCT ATACTGGGCT 
GACGCCGGCA TGAAGACAAT TGAATTTGCT GGACTGGATG GCAGTAAGAG GAAGGTGCTG 
ATTGGAAGCC AGCTCCCCCA CCCATTTGGG CTGACCCTCT ATGGAGAGCG CATCTATTGG 
ACTGACTGGC AGACCAAGAG CATACAGAGC GCTGACCGGC TGACAGGGCT GGACCGGGAG 
ACTCTGCAGG AGAACCTGGA AAACCTAATG GACATCCATG TCTTCCACCG CCGCCGGCCC 
CCAGTGTCTA CACCATGTGC TATGGAGAAT GGCGGCTGTA GCCACCTGTG TCTTAGGTCC 
CCAAATCCAA GCGGATTCAG CTGTACCTGC CCCACAGGCA TCAACCTGCT GTCTGATGGC 
AAGACCTGCT CACCAGGCAT GAACAGTTTC CTCATCTTCG CCAGGAGGAT AGACATTCGC 
ATGGTCTCCC TGGACATCCC TTATTTTGCT GATGTGGTGG TACCAATCAA CATTACCATG 
AAGAACACCA TTGCCATTGG AGTAGACCCC CAGGAAGGAA AGGTGTACTG GTCTGACAGC 
ACACTGCACA GGATCAGTCG TGCCAATCTG GATGGCTCAC AGCATGAGGA CATCATCACC 
ACAGGGCTAC AGACCACAGA TGGGCTCGCG GTTGATGCCA TTGGCCGGAA AGTATACTGG 
ACAGACACGG GAACAAACCG GATTGAAGTG GGCAACCTGG ACGGGTCCAT GCGGAAAGTG 
TTGGTGTGGC AGAACCTTGA CAGTCCCCGG GCCATCGTAC TGTACCATGA GATGGGGTTT 
ATGTACTGGA CAGACTGGGG GGAGAATGCC AAGTTAGAGC GGTCCGGAAT GGATGGCTCA 
GACCGCGCGG TGCTCATCAA CAACAACCTA GGATGGCCCA ATGGACTGAC TGTGGACAAG 
GCCAGCTCCC AACTGCTATG GGCCGATGCC CACACCGAGC GAATTGAGGC TGCTGACCTG 
AATGGTGCCA ATCGGCATAC ATTGGTGTCA CCGGTGCAGC ACCCATATGG CCTCACCCTG 
CTCGACTCCT ATATCTACTG GACTGACTGG CAGACTCGGA GCATCCACCG TGCTGACAAG 
GGTACTGGCA GCAATGTCAT CCTCGTGAGG TCCAACCTGC CAGGCCTCAT GGACATGCAG 
GCTGTGGACC GGGCACAGCC ACTAGGTTTT AACAAGTGCG GCTCGAGAAA TGGCGGCTGC 
TCCCACCTCT GCTTGCCTCG GCCTTCTGGC TTCTCCTGTG CCTGCCCCAC TGGCATCCAG 
CTGAAGGGAG ATGGGAAGAC CTGTGATCCC TCTCCTGAGA CCTACCTGCT CTTCTCCAGC 
CGTGGCTCCA TCCGGCGTAT CTCACTGGAC ACCAGTGACC ACACCGATGT GCATGTCCCT 
GTTCCTGAGC TCAACAATGT CATCTCCCTG GACTATGACA GCGTGGATGG AAAGGTCTAT 
TACACAGATG TGTTCCTGGA TGTTATCAGG CGAGCAGACC TGAACGGCAG CAACATGGAG 
ACAGTGATCG GGCGAGGGCT GAAGACCACT GACGGGCTGG CAGTGGACTG GGTGGCCAGG 
AACCTGTACT GGACAGACAC AGGTCGAAAT ACCATTGAGG CGTCCAGGCT GGATGGTTCC 
TGCCGCAAAG TACTGATCAA CAATAGCCTG GATGAGCCCC GGGCCATTGC TGTTTTCCCC 
AGGAAGGGGT ACCTCTTCTG GACAGACTGG GGCCACATTG CCAAGATCGA ACGGGCAAAC 
TTGGATGGTT CTGAGCGGAA GGTCCTCATC AACACAGACC TGGGTTGGCC CAATGGCCTT 
ACCCTGGACT ATGATACCCG CAGGATCTAC TGGGTGGATG CGCATCTGGA CCGGATCGAG 
AGTGCTGACC TCAATGGGAA ACTGCGGCAG GTCTTGGTCA GCCATGTGTC CCACCCCTTT 
GCCCTCACAC AGCAAGACAG GTGGATCTAC TGGACAGACT GGCAGACCAA GTCAATCCAG 
CGTGTTGACA AATACTCAGG CCGGAACAAG GAGACAGTGC TGGCAAATGT GGAAGGACTC 
ATGGATATCA TCGTGGTTTC CCCTCAGCGG CAGACAGGGA CCAATGCCTG TGGTGTGAAC 
AATGGTGGCT GCACCCACCT CTGCTTTGCC AGAGCCTCGG ACTTCGTATG TGCCTGTCCT 
GACGAACCTG ATAGCCGGCC CTGCTCCCTT GTGCCTGGCC TGGTACCACC AGCTCCTAGG 
GCTACTGGCA TGAGTGAAAA GAGCCCAGTG CTACCCAACA CACCACCTAC CACCTTGTAT 
TCTTCAACCA CCCGGACCCG CACGTCTCTG GAGGAGGTGG AAGGAAGATG CTCTGAAAGG 
GATGCCAGGC TGGGCCTCTG TGCACGTTCC AATGACGCTG TTCCTGCTGC TCCAGGGGAA 
GGACTTCATA TCAGCTACGC CATTGGTGGA CTCCTCAGTA TTCTGCTGAT TTTGGTGGTG 
ATTGCAGCTT TGATGCTGTA CAGACACAAA AAATCCAAGT TCACTGATCC TGGAATGGGG 
AACCTCACCT ACAGCAACCC CTCCTACCGA ACATCCACAC AGGAAGTGAA GATTGAAGCA 
ATCCCCAAAC CAGCCATGTA CAACCAGCTG TGCTATAAGA AAGAGGGAGG GCCTGACCAT 
AACTACACCA AGGAGAAGAT CAAGATCGTA GAGGGAATCT GCCTCCTGTC TGGGGATGAT 
GCTGAGTGGG ATGACCTCAA GCAACTGCGA AGCTCACGGG GGGGCCTCCT CCGGGATCAT 
GTATGCATGA AGACAGACAC GGTGTCCATC CAGGCCAGCT CTGGCTCCCT GGATGACACA 
GAGACGGAGC AGCTGTTACA GGAAGAGCAG TCTGAGTGTA GCAGCGTCCA TACTGCAGCC 
ACTCCAGAAA GACGAGGCTC TCTGCCAGAC ACGGGCTGGA AACATGAACG CAAGCTCTCC 
TCAGAGAGCC AGGTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRP4 ( NM_002334.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_002325.2 Homo sapiens LDL receptor related protein 4 (LRP4), mRNA.

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CloneID	OHu25180
Clone ID Related Accession (Same CDS sequence)	NM_002334.3 , NM_002334.4
Accession Version	NM_002334.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5718bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-06
Organism	Homo sapiens(human)
Product	low-density lipoprotein receptor-related protein 4 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC021573.10. On Nov 23, 2018 this sequence version replaced NM_002334.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB084910.1, AB231861.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000378623.6/ ENSP00000367888.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAGGCGGC AGTGGGGCGC GCTGCTGCTT GGCGCCCTGC TCTGCGCACA CGGCCTGGCC 
AGCAGCCCCG AGTGTGCTTG TGGTCGGAGC CACTTCACAT GTGCAGTGAG TGCTCTTGGA 
GAGTGTACCT GCATCCCTGC CCAGTGGCAG TGTGATGGAG ACAATGACTG CGGGGACCAC 
AGCGATGAGG ATGGATGTAT ACTACCTACC TGTTCCCCTC TTGACTTTCA CTGTGACAAT 
GGCAAGTGCA TCCGCCGCTC CTGGGTGTGT GACGGGGACA ACGACTGTGA GGATGACTCG 
GATGAGCAGG ACTGTCCCCC CCGGGAGTGT GAGGAGGACG AGTTTCCCTG CCAGAATGGC 
TACTGCATCC GGAGTCTGTG GCACTGCGAT GGTGACAATG ACTGTGGCGA CAACAGCGAT 
GAGCAGTGTG ACATGCGCAA GTGCTCCGAC AAGGAGTTCC GCTGTAGTGA CGGAAGCTGC 
ATTGCTGAGC ATTGGTACTG CGACGGTGAC ACCGACTGCA AAGATGGCTC CGATGAGGAG 
AACTGTCCCT CAGCAGTGCC AGCGCCCCCC TGCAACCTGG AGGAGTTCCA GTGTGCCTAT 
GGACGCTGCA TCCTCGACAT CTACCACTGC GATGGCGACG ATGACTGTGG AGACTGGTCA 
GACGAGTCTG ACTGCTCCTC CCACCAGCCC TGCCGCTCTG GGGAGTTCAT GTGTGACAGT 
GGCCTGTGCA TCAATGCAGG CTGGCGCTGC GATGGTGACG CGGACTGTGA TGACCAGTCT 
GATGAGCGCA ACTGCACCAC CTCCATGTGT ACGGCAGAAC AGTTCCGCTG TCACTCAGGC 
CGCTGTGTCC GCCTGTCCTG GCGCTGTGAT GGGGAGGACG ACTGTGCAGA CAACAGCGAT 
GAAGAGAACT GTGAGAATAC AGGAAGCCCC CAATGTGCCT TGGACCAGTT CCTGTGTTGG 
AATGGGCGCT GCATTGGGCA GAGGAAGCTG TGCAACGGGG TCAACGACTG TGGTGACAAC 
AGCGACGAAA GCCCACAGCA GAATTGCCGG CCCCGGACGG GTGAGGAGAA CTGCAATGTT 
AACAACGGTG GCTGTGCCCA GAAGTGCCAG ATGGTGCGGG GGGCAGTGCA GTGTACCTGC 
CACACAGGCT ACCGGCTCAC AGAGGATGGG CACACGTGCC AAGATGTGAA TGAATGTGCC 
GAGGAGGGGT ATTGCAGCCA GGGCTGCACC AACAGCGAAG GGGCTTTCCA ATGCTGGTGT 
GAAACAGGCT ATGAACTACG GCCCGACCGG CGCAGCTGCA AGGCTCTGGG GCCAGAGCCT 
GTGCTGCTGT TCGCCAATCG CATCGACATC CGGCAGGTGC TGCCACACCG CTCTGAGTAC 
ACACTGCTGC TTAACAACCT GGAGAATGCC ATTGCCCTTG ATTTCCACCA CCGCCGCGAG 
CTTGTCTTCT GGTCAGATGT CACCCTGGAC CGGATCCTCC GTGCCAACCT CAACGGCAGC 
AACGTGGAGG AGGTTGTGTC TACTGGGCTG GAGAGCCCAG GGGGCCTGGC TGTGGATTGG 
GTCCATGACA AACTCTACTG GACCGACTCA GGCACCTCGA GGATTGAGGT GGCCAATCTG 
GATGGGGCCC ACCGGAAAGT GTTGCTGTGG CAGAACCTGG AGAAGCCCCG GGCCATTGCC 
TTGCATCCCA TGGAGGGTAC CATTTACTGG ACAGACTGGG GCAACACCCC CCGTATTGAG 
GCCTCCAGCA TGGATGGCTC TGGACGCCGC ATCATTGCCG ATACCCATCT CTTCTGGCCC 
AATGGCCTCA CCATCGACTA TGCCGGGCGC CGTATGTACT GGGTGGATGC TAAGCACCAT 
GTCATCGAGA GGGCCAATCT GGATGGGAGT CACCGTAAGG CTGTCATTAG CCAGGGCCTC 
CCGCATCCCT TCGCCATCAC AGTGTTTGAA GACAGCCTGT ACTGGACAGA CTGGCACACC 
AAGAGCATCA ATAGCGCTAA CAAATTTACG GGGAAGAACC AGGAAATCAT TCGCAACAAA 
CTCCACTTCC CTATGGACAT CCACACCTTG CACCCCCAGC GCCAACCTGC AGGGAAAAAC 
CGCTGTGGGG ACAACAACGG AGGCTGCACG CACCTGTGTC TGCCCAGTGG CCAGAACTAC 
ACCTGTGCCT GCCCCACTGG CTTCCGCAAG ATCAGCAGCC ACGCCTGTGC CCAGAGTCTT 
GACAAGTTCC TGCTTTTTGC CCGAAGGATG GACATCCGTC GAATCAGCTT TGACACAGAG 
GACCTGTCTG ATGATGTCAT CCCACTGGCT GACGTGCGCA GTGCTGTGGC CCTTGACTGG 
GACTCCCGGG ATGACCACGT GTACTGGACA GATGTCAGCA CTGATACCAT CAGCAGGGCC 
AAGTGGGATG GAACAGGACA GGAGGTGGTA GTGGATACCA GTTTGGAGAG CCCAGCTGGC 
CTGGCCATTG ATTGGGTCAC CAACAAACTG TACTGGACAG ATGCAGGTAC AGACCGGATT 
GAAGTAGCCA ACACAGATGG CAGCATGAGA ACAGTACTCA TCTGGGAGAA CCTTGATCGT 
CCTCGGGACA TCGTGGTGGA ACCCATGGGC GGGTACATGT ATTGGACTGA CTGGGGTGCG 
AGCCCCAAGA TTGAACGAGC TGGCATGGAT GCCTCAGGCC GCCAAGTCAT TATCTCTTCT 
AATCTGACCT GGCCTAATGG GTTAGCTATT GATTATGGGT CCCAGCGTCT ATACTGGGCT 
GACGCCGGCA TGAAGACAAT TGAATTTGCT GGACTGGATG GCAGTAAGAG GAAGGTGCTG 
ATTGGAAGCC AGCTCCCCCA CCCATTTGGG CTGACCCTCT ATGGAGAGCG CATCTATTGG 
ACTGACTGGC AGACCAAGAG CATACAGAGC GCTGACCGGC TGACAGGGCT GGACCGGGAG 
ACTCTGCAGG AGAACCTGGA AAACCTAATG GACATCCATG TCTTCCACCG CCGCCGGCCC 
CCAGTGTCTA CACCATGTGC TATGGAGAAT GGCGGCTGTA GCCACCTGTG TCTTAGGTCC 
CCAAATCCAA GCGGATTCAG CTGTACCTGC CCCACAGGCA TCAACCTGCT GTCTGATGGC 
AAGACCTGCT CACCAGGCAT GAACAGTTTC CTCATCTTCG CCAGGAGGAT AGACATTCGC 
ATGGTCTCCC TGGACATCCC TTATTTTGCT GATGTGGTGG TACCAATCAA CATTACCATG 
AAGAACACCA TTGCCATTGG AGTAGACCCC CAGGAAGGAA AGGTGTACTG GTCTGACAGC 
ACACTGCACA GGATCAGTCG TGCCAATCTG GATGGCTCAC AGCATGAGGA CATCATCACC 
ACAGGGCTAC AGACCACAGA TGGGCTCGCG GTTGATGCCA TTGGCCGGAA AGTATACTGG 
ACAGACACGG GAACAAACCG GATTGAAGTG GGCAACCTGG ACGGGTCCAT GCGGAAAGTG 
TTGGTGTGGC AGAACCTTGA CAGTCCCCGG GCCATCGTAC TGTACCATGA GATGGGGTTT 
ATGTACTGGA CAGACTGGGG GGAGAATGCC AAGTTAGAGC GGTCCGGAAT GGATGGCTCA 
GACCGCGCGG TGCTCATCAA CAACAACCTA GGATGGCCCA ATGGACTGAC TGTGGACAAG 
GCCAGCTCCC AACTGCTATG GGCCGATGCC CACACCGAGC GAATTGAGGC TGCTGACCTG 
AATGGTGCCA ATCGGCATAC ATTGGTGTCA CCGGTGCAGC ACCCATATGG CCTCACCCTG 
CTCGACTCCT ATATCTACTG GACTGACTGG CAGACTCGGA GCATCCACCG TGCTGACAAG 
GGTACTGGCA GCAATGTCAT CCTCGTGAGG TCCAACCTGC CAGGCCTCAT GGACATGCAG 
GCTGTGGACC GGGCACAGCC ACTAGGTTTT AACAAGTGCG GCTCGAGAAA TGGCGGCTGC 
TCCCACCTCT GCTTGCCTCG GCCTTCTGGC TTCTCCTGTG CCTGCCCCAC TGGCATCCAG 
CTGAAGGGAG ATGGGAAGAC CTGTGATCCC TCTCCTGAGA CCTACCTGCT CTTCTCCAGC 
CGTGGCTCCA TCCGGCGTAT CTCACTGGAC ACCAGTGACC ACACCGATGT GCATGTCCCT 
GTTCCTGAGC TCAACAATGT CATCTCCCTG GACTATGACA GCGTGGATGG AAAGGTCTAT 
TACACAGATG TGTTCCTGGA TGTTATCAGG CGAGCAGACC TGAACGGCAG CAACATGGAG 
ACAGTGATCG GGCGAGGGCT GAAGACCACT GACGGGCTGG CAGTGGACTG GGTGGCCAGG 
AACCTGTACT GGACAGACAC AGGTCGAAAT ACCATTGAGG CGTCCAGGCT GGATGGTTCC 
TGCCGCAAAG TACTGATCAA CAATAGCCTG GATGAGCCCC GGGCCATTGC TGTTTTCCCC 
AGGAAGGGGT ACCTCTTCTG GACAGACTGG GGCCACATTG CCAAGATCGA ACGGGCAAAC 
TTGGATGGTT CTGAGCGGAA GGTCCTCATC AACACAGACC TGGGTTGGCC CAATGGCCTT 
ACCCTGGACT ATGATACCCG CAGGATCTAC TGGGTGGATG CGCATCTGGA CCGGATCGAG 
AGTGCTGACC TCAATGGGAA ACTGCGGCAG GTCTTGGTCA GCCATGTGTC CCACCCCTTT 
GCCCTCACAC AGCAAGACAG GTGGATCTAC TGGACAGACT GGCAGACCAA GTCAATCCAG 
CGTGTTGACA AATACTCAGG CCGGAACAAG GAGACAGTGC TGGCAAATGT GGAAGGACTC 
ATGGATATCA TCGTGGTTTC CCCTCAGCGG CAGACAGGGA CCAATGCCTG TGGTGTGAAC 
AATGGTGGCT GCACCCACCT CTGCTTTGCC AGAGCCTCGG ACTTCGTATG TGCCTGTCCT 
GACGAACCTG ATAGCCGGCC CTGCTCCCTT GTGCCTGGCC TGGTACCACC AGCTCCTAGG 
GCTACTGGCA TGAGTGAAAA GAGCCCAGTG CTACCCAACA CACCACCTAC CACCTTGTAT 
TCTTCAACCA CCCGGACCCG CACGTCTCTG GAGGAGGTGG AAGGAAGATG CTCTGAAAGG 
GATGCCAGGC TGGGCCTCTG TGCACGTTCC AATGACGCTG TTCCTGCTGC TCCAGGGGAA 
GGACTTCATA TCAGCTACGC CATTGGTGGA CTCCTCAGTA TTCTGCTGAT TTTGGTGGTG 
ATTGCAGCTT TGATGCTGTA CAGACACAAA AAATCCAAGT TCACTGATCC TGGAATGGGG 
AACCTCACCT ACAGCAACCC CTCCTACCGA ACATCCACAC AGGAAGTGAA GATTGAAGCA 
ATCCCCAAAC CAGCCATGTA CAACCAGCTG TGCTATAAGA AAGAGGGAGG GCCTGACCAT 
AACTACACCA AGGAGAAGAT CAAGATCGTA GAGGGAATCT GCCTCCTGTC TGGGGATGAT 
GCTGAGTGGG ATGACCTCAA GCAACTGCGA AGCTCACGGG GGGGCCTCCT CCGGGATCAT 
GTATGCATGA AGACAGACAC GGTGTCCATC CAGGCCAGCT CTGGCTCCCT GGATGACACA 
GAGACGGAGC AGCTGTTACA GGAAGAGCAG TCTGAGTGTA GCAGCGTCCA TACTGCAGCC 
ACTCCAGAAA GACGAGGCTC TCTGCCAGAC ACGGGCTGGA AACATGAACG CAAGCTCTCC 
TCAGAGAGCC AGGTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002325.2
CDS	172..5889
Translation	MRRQWGALLLGALLCAHGLASSPECACGRSHFTCAVSALGECTCIPAQWQCDGDNDCGDHSDEDGCILPTCSPLDFHCDNGKCIRRSWVCDGDNDCEDDSDEQDCPPRECEEDEFPCQNGYCIRSLWHCDGDNDCGDNSDEQCDMRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEENCPSAVPAPPCNLEEFQCAYGRCILDIYHCDGDDDCGDWSDESDCSSHQPCRSGEFMCDSGLCINAGWRCDGDADCDDQSDERNCTTSMCTAEQFRCHSGRCVRLSWRCDGEDDCADNSDEENCENTGSPQCALDQFLCWNGRCIGQRKLCNGVNDCGDNSDESPQQNCRPRTGEENCNVNNGGCAQKCQMVRGAVQCTCHTGYRLTEDGHTCQDVNECAEEGYCSQGCTNSEGAFQCWCETGYELRPDRRSCKALGPEPVLLFANRIDIRQVLPHRSEYTLLLNNLENAIALDFHHRRELVFWSDVTLDRILRANLNGSNVEEVVSTGLESPGGLAVDWVHDKLYWTDSGTSRIEVANLDGAHRKVLLWQNLEKPRAIALHPMEGTIYWTDWGNTPRIEASSMDGSGRRIIADTHLFWPNGLTIDYAGRRMYWVDAKHHVIERANLDGSHRKAVISQGLPHPFAITVFEDSLYWTDWHTKSINSANKFTGKNQEIIRNKLHFPMDIHTLHPQRQPAGKNRCGDNNGGCTHLCLPSGQNYTCACPTGFRKISSHACAQSLDKFLLFARRMDIRRISFDTEDLSDDVIPLADVRSAVALDWDSRDDHVYWTDVSTDTISRAKWDGTGQEVVVDTSLESPAGLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWENLDRPRDIVVEPMGGYMYWTDWGASPKIERAGMDASGRQVIISSNLTWPNGLAIDYGSQRLYWADAGMKTIEFAGLDGSKRKVLIGSQLPHPFGLTLYGERIYWTDWQTKSIQSADRLTGLDRETLQENLENLMDIHVFHRRRPPVSTPCAMENGGCSHLCLRSPNPSGFSCTCPTGINLLSDGKTCSPGMNSFLIFARRIDIRMVSLDIPYFADVVVPINITMKNTIAIGVDPQEGKVYWSDSTLHRISRANLDGSQHEDIITTGLQTTDGLAVDAIGRKVYWTDTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIVLYHEMGFMYWTDWGENAKLERSGMDGSDRAVLINNNLGWPNGLTVDKASSQLLWADAHTERIEAADLNGANRHTLVSPVQHPYGLTLLDSYIYWTDWQTRSIHRADKGTGSNVILVRSNLPGLMDMQAVDRAQPLGFNKCGSRNGGCSHLCLPRPSGFSCACPTGIQLKGDGKTCDPSPETYLLFSSRGSIRRISLDTSDHTDVHVPVPELNNVISLDYDSVDGKVYYTDVFLDVIRRADLNGSNMETVIGRGLKTTDGLAVDWVARNLYWTDTGRNTIEASRLDGSCRKVLINNSLDEPRAIAVFPRKGYLFWTDWGHIAKIERANLDGSERKVLINTDLGWPNGLTLDYDTRRIYWVDAHLDRIESADLNGKLRQVLVSHVSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGRNKETVLANVEGLMDIIVVSPQRQTGTNACGVNNGGCTHLCFARASDFVCACPDEPDSRPCSLVPGLVPPAPRATGMSEKSPVLPNTPPTTLYSSTTRTRTSLEEVEGRCSERDARLGLCARSNDAVPAAPGEGLHISYAIGGLLSILLILVVIAALMLYRHKKSKFTDPGMGNLTYSNPSYRTSTQEVKIEAIPKPAMYNQLCYKKEGGPDHNYTKEKIKIVEGICLLSGDDAEWDDLKQLRSSRGGLLRDHVCMKTDTVSIQASSGSLDDTETEQLLQEEQSECSSVHTAATPERRGSLPDTGWKHERKLSSESQV

Target ORF information:

RefSeq Version	NM_002334.4
Organism	Homo sapiens(human)
Definition	Homo sapiens LDL receptor related protein 4 (LRP4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002334.4

ORF Insert Sequence:

ATGAGGCGGC AGTGGGGCGC GCTGCTGCTT GGCGCCCTGC TCTGCGCACA CGGCCTGGCC 
AGCAGCCCCG AGTGTGCTTG TGGTCGGAGC CACTTCACAT GTGCAGTGAG TGCTCTTGGA 
GAGTGTACCT GCATCCCTGC CCAGTGGCAG TGTGATGGAG ACAATGACTG CGGGGACCAC 
AGCGATGAGG ATGGATGTAT ACTACCTACC TGTTCCCCTC TTGACTTTCA CTGTGACAAT 
GGCAAGTGCA TCCGCCGCTC CTGGGTGTGT GACGGGGACA ACGACTGTGA GGATGACTCG 
GATGAGCAGG ACTGTCCCCC CCGGGAGTGT GAGGAGGACG AGTTTCCCTG CCAGAATGGC 
TACTGCATCC GGAGTCTGTG GCACTGCGAT GGTGACAATG ACTGTGGCGA CAACAGCGAT 
GAGCAGTGTG ACATGCGCAA GTGCTCCGAC AAGGAGTTCC GCTGTAGTGA CGGAAGCTGC 
ATTGCTGAGC ATTGGTACTG CGACGGTGAC ACCGACTGCA AAGATGGCTC CGATGAGGAG 
AACTGTCCCT CAGCAGTGCC AGCGCCCCCC TGCAACCTGG AGGAGTTCCA GTGTGCCTAT 
GGACGCTGCA TCCTCGACAT CTACCACTGC GATGGCGACG ATGACTGTGG AGACTGGTCA 
GACGAGTCTG ACTGCTCCTC CCACCAGCCC TGCCGCTCTG GGGAGTTCAT GTGTGACAGT 
GGCCTGTGCA TCAATGCAGG CTGGCGCTGC GATGGTGACG CGGACTGTGA TGACCAGTCT 
GATGAGCGCA ACTGCACCAC CTCCATGTGT ACGGCAGAAC AGTTCCGCTG TCACTCAGGC 
CGCTGTGTCC GCCTGTCCTG GCGCTGTGAT GGGGAGGACG ACTGTGCAGA CAACAGCGAT 
GAAGAGAACT GTGAGAATAC AGGAAGCCCC CAATGTGCCT TGGACCAGTT CCTGTGTTGG 
AATGGGCGCT GCATTGGGCA GAGGAAGCTG TGCAACGGGG TCAACGACTG TGGTGACAAC 
AGCGACGAAA GCCCACAGCA GAATTGCCGG CCCCGGACGG GTGAGGAGAA CTGCAATGTT 
AACAACGGTG GCTGTGCCCA GAAGTGCCAG ATGGTGCGGG GGGCAGTGCA GTGTACCTGC 
CACACAGGCT ACCGGCTCAC AGAGGATGGG CACACGTGCC AAGATGTGAA TGAATGTGCC 
GAGGAGGGGT ATTGCAGCCA GGGCTGCACC AACAGCGAAG GGGCTTTCCA ATGCTGGTGT 
GAAACAGGCT ATGAACTACG GCCCGACCGG CGCAGCTGCA AGGCTCTGGG GCCAGAGCCT 
GTGCTGCTGT TCGCCAATCG CATCGACATC CGGCAGGTGC TGCCACACCG CTCTGAGTAC 
ACACTGCTGC TTAACAACCT GGAGAATGCC ATTGCCCTTG ATTTCCACCA CCGCCGCGAG 
CTTGTCTTCT GGTCAGATGT CACCCTGGAC CGGATCCTCC GTGCCAACCT CAACGGCAGC 
AACGTGGAGG AGGTTGTGTC TACTGGGCTG GAGAGCCCAG GGGGCCTGGC TGTGGATTGG 
GTCCATGACA AACTCTACTG GACCGACTCA GGCACCTCGA GGATTGAGGT GGCCAATCTG 
GATGGGGCCC ACCGGAAAGT GTTGCTGTGG CAGAACCTGG AGAAGCCCCG GGCCATTGCC 
TTGCATCCCA TGGAGGGTAC CATTTACTGG ACAGACTGGG GCAACACCCC CCGTATTGAG 
GCCTCCAGCA TGGATGGCTC TGGACGCCGC ATCATTGCCG ATACCCATCT CTTCTGGCCC 
AATGGCCTCA CCATCGACTA TGCCGGGCGC CGTATGTACT GGGTGGATGC TAAGCACCAT 
GTCATCGAGA GGGCCAATCT GGATGGGAGT CACCGTAAGG CTGTCATTAG CCAGGGCCTC 
CCGCATCCCT TCGCCATCAC AGTGTTTGAA GACAGCCTGT ACTGGACAGA CTGGCACACC 
AAGAGCATCA ATAGCGCTAA CAAATTTACG GGGAAGAACC AGGAAATCAT TCGCAACAAA 
CTCCACTTCC CTATGGACAT CCACACCTTG CACCCCCAGC GCCAACCTGC AGGGAAAAAC 
CGCTGTGGGG ACAACAACGG AGGCTGCACG CACCTGTGTC TGCCCAGTGG CCAGAACTAC 
ACCTGTGCCT GCCCCACTGG CTTCCGCAAG ATCAGCAGCC ACGCCTGTGC CCAGAGTCTT 
GACAAGTTCC TGCTTTTTGC CCGAAGGATG GACATCCGTC GAATCAGCTT TGACACAGAG 
GACCTGTCTG ATGATGTCAT CCCACTGGCT GACGTGCGCA GTGCTGTGGC CCTTGACTGG 
GACTCCCGGG ATGACCACGT GTACTGGACA GATGTCAGCA CTGATACCAT CAGCAGGGCC 
AAGTGGGATG GAACAGGACA GGAGGTGGTA GTGGATACCA GTTTGGAGAG CCCAGCTGGC 
CTGGCCATTG ATTGGGTCAC CAACAAACTG TACTGGACAG ATGCAGGTAC AGACCGGATT 
GAAGTAGCCA ACACAGATGG CAGCATGAGA ACAGTACTCA TCTGGGAGAA CCTTGATCGT 
CCTCGGGACA TCGTGGTGGA ACCCATGGGC GGGTACATGT ATTGGACTGA CTGGGGTGCG 
AGCCCCAAGA TTGAACGAGC TGGCATGGAT GCCTCAGGCC GCCAAGTCAT TATCTCTTCT 
AATCTGACCT GGCCTAATGG GTTAGCTATT GATTATGGGT CCCAGCGTCT ATACTGGGCT 
GACGCCGGCA TGAAGACAAT TGAATTTGCT GGACTGGATG GCAGTAAGAG GAAGGTGCTG 
ATTGGAAGCC AGCTCCCCCA CCCATTTGGG CTGACCCTCT ATGGAGAGCG CATCTATTGG 
ACTGACTGGC AGACCAAGAG CATACAGAGC GCTGACCGGC TGACAGGGCT GGACCGGGAG 
ACTCTGCAGG AGAACCTGGA AAACCTAATG GACATCCATG TCTTCCACCG CCGCCGGCCC 
CCAGTGTCTA CACCATGTGC TATGGAGAAT GGCGGCTGTA GCCACCTGTG TCTTAGGTCC 
CCAAATCCAA GCGGATTCAG CTGTACCTGC CCCACAGGCA TCAACCTGCT GTCTGATGGC 
AAGACCTGCT CACCAGGCAT GAACAGTTTC CTCATCTTCG CCAGGAGGAT AGACATTCGC 
ATGGTCTCCC TGGACATCCC TTATTTTGCT GATGTGGTGG TACCAATCAA CATTACCATG 
AAGAACACCA TTGCCATTGG AGTAGACCCC CAGGAAGGAA AGGTGTACTG GTCTGACAGC 
ACACTGCACA GGATCAGTCG TGCCAATCTG GATGGCTCAC AGCATGAGGA CATCATCACC 
ACAGGGCTAC AGACCACAGA TGGGCTCGCG GTTGATGCCA TTGGCCGGAA AGTATACTGG 
ACAGACACGG GAACAAACCG GATTGAAGTG GGCAACCTGG ACGGGTCCAT GCGGAAAGTG 
TTGGTGTGGC AGAACCTTGA CAGTCCCCGG GCCATCGTAC TGTACCATGA GATGGGGTTT 
ATGTACTGGA CAGACTGGGG GGAGAATGCC AAGTTAGAGC GGTCCGGAAT GGATGGCTCA 
GACCGCGCGG TGCTCATCAA CAACAACCTA GGATGGCCCA ATGGACTGAC TGTGGACAAG 
GCCAGCTCCC AACTGCTATG GGCCGATGCC CACACCGAGC GAATTGAGGC TGCTGACCTG 
AATGGTGCCA ATCGGCATAC ATTGGTGTCA CCGGTGCAGC ACCCATATGG CCTCACCCTG 
CTCGACTCCT ATATCTACTG GACTGACTGG CAGACTCGGA GCATCCACCG TGCTGACAAG 
GGTACTGGCA GCAATGTCAT CCTCGTGAGG TCCAACCTGC CAGGCCTCAT GGACATGCAG 
GCTGTGGACC GGGCACAGCC ACTAGGTTTT AACAAGTGCG GCTCGAGAAA TGGCGGCTGC 
TCCCACCTCT GCTTGCCTCG GCCTTCTGGC TTCTCCTGTG CCTGCCCCAC TGGCATCCAG 
CTGAAGGGAG ATGGGAAGAC CTGTGATCCC TCTCCTGAGA CCTACCTGCT CTTCTCCAGC 
CGTGGCTCCA TCCGGCGTAT CTCACTGGAC ACCAGTGACC ACACCGATGT GCATGTCCCT 
GTTCCTGAGC TCAACAATGT CATCTCCCTG GACTATGACA GCGTGGATGG AAAGGTCTAT 
TACACAGATG TGTTCCTGGA TGTTATCAGG CGAGCAGACC TGAACGGCAG CAACATGGAG 
ACAGTGATCG GGCGAGGGCT GAAGACCACT GACGGGCTGG CAGTGGACTG GGTGGCCAGG 
AACCTGTACT GGACAGACAC AGGTCGAAAT ACCATTGAGG CGTCCAGGCT GGATGGTTCC 
TGCCGCAAAG TACTGATCAA CAATAGCCTG GATGAGCCCC GGGCCATTGC TGTTTTCCCC 
AGGAAGGGGT ACCTCTTCTG GACAGACTGG GGCCACATTG CCAAGATCGA ACGGGCAAAC 
TTGGATGGTT CTGAGCGGAA GGTCCTCATC AACACAGACC TGGGTTGGCC CAATGGCCTT 
ACCCTGGACT ATGATACCCG CAGGATCTAC TGGGTGGATG CGCATCTGGA CCGGATCGAG 
AGTGCTGACC TCAATGGGAA ACTGCGGCAG GTCTTGGTCA GCCATGTGTC CCACCCCTTT 
GCCCTCACAC AGCAAGACAG GTGGATCTAC TGGACAGACT GGCAGACCAA GTCAATCCAG 
CGTGTTGACA AATACTCAGG CCGGAACAAG GAGACAGTGC TGGCAAATGT GGAAGGACTC 
ATGGATATCA TCGTGGTTTC CCCTCAGCGG CAGACAGGGA CCAATGCCTG TGGTGTGAAC 
AATGGTGGCT GCACCCACCT CTGCTTTGCC AGAGCCTCGG ACTTCGTATG TGCCTGTCCT 
GACGAACCTG ATAGCCGGCC CTGCTCCCTT GTGCCTGGCC TGGTACCACC AGCTCCTAGG 
GCTACTGGCA TGAGTGAAAA GAGCCCAGTG CTACCCAACA CACCACCTAC CACCTTGTAT 
TCTTCAACCA CCCGGACCCG CACGTCTCTG GAGGAGGTGG AAGGAAGATG CTCTGAAAGG 
GATGCCAGGC TGGGCCTCTG TGCACGTTCC AATGACGCTG TTCCTGCTGC TCCAGGGGAA 
GGACTTCATA TCAGCTACGC CATTGGTGGA CTCCTCAGTA TTCTGCTGAT TTTGGTGGTG 
ATTGCAGCTT TGATGCTGTA CAGACACAAA AAATCCAAGT TCACTGATCC TGGAATGGGG 
AACCTCACCT ACAGCAACCC CTCCTACCGA ACATCCACAC AGGAAGTGAA GATTGAAGCA 
ATCCCCAAAC CAGCCATGTA CAACCAGCTG TGCTATAAGA AAGAGGGAGG GCCTGACCAT 
AACTACACCA AGGAGAAGAT CAAGATCGTA GAGGGAATCT GCCTCCTGTC TGGGGATGAT 
GCTGAGTGGG ATGACCTCAA GCAACTGCGA AGCTCACGGG GGGGCCTCCT CCGGGATCAT 
GTATGCATGA AGACAGACAC GGTGTCCATC CAGGCCAGCT CTGGCTCCCT GGATGACACA 
GAGACGGAGC AGCTGTTACA GGAAGAGCAG TCTGAGTGTA GCAGCGTCCA TACTGCAGCC 
ACTCCAGAAA GACGAGGCTC TCTGCCAGAC ACGGGCTGGA AACATGAACG CAAGCTCTCC 
TCAGAGAGCC AGGTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRP4 ( XM_011520102.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011518404.1 Homo sapiens low density lipoprotein receptor-related protein 4 (LRP4), transcript variant X1, mRNA.

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CloneID	OHu58774
Clone ID Related Accession (Same CDS sequence)	XM_011520102.1
Accession Version	XM_011520102.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5931bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	low-density lipoprotein receptor-related protein 4 isoform X1
Comment

ATGTCCCTTT CGAAACGGGC CACTGAGGAG AAGACTTCAC CTGGTAGATT TTCCAAACCA 
ACCAAGTTAA GCTGGCCTCT AGGAATCGGG AATAAAAGGG ACCATGGGAC AGAAATAAGT 
AGAAACATGG CGTGTCAGTT TCACAGCCGG ATAATACAGC TGGTGAAAGG AACTCTTGTA 
GGAGAAAGGA GTAAACAAAA CCTGGGTAGG ACAAAGAGGC TGCCTTGCAA ACGAGAAGAT 
TCCTGTTCTC TCCAGCACTG GTTAGGCCTG GCCAGCAGCC CCGAGTGTGC TTGTGGTCGG 
AGCCACTTCA CATGTGCAGT GAGTGCTCTT GGAGAGTGTA CCTGCATCCC TGCCCAGTGG 
CAGTGTGATG GAGACAATGA CTGCGGGGAC CACAGCGATG AGGATGGATG TATACTACCT 
ACCTGTTCCC CTCTTGACTT TCACTGTGAC AATGGCAAGT GCATCCGCCG CTCCTGGGTG 
TGTGACGGGG ACAACGACTG TGAGGATGAC TCGGATGAGC AGGACTGTCC CCCCCGGGAG 
TGTGAGGAGG ACGAGTTTCC CTGCCAGAAT GGCTACTGCA TCCGGAGTCT GTGGCACTGC 
GATGGTGACA ATGACTGTGG CGACAACAGC GATGAGCAGT GTGACATGCG CAAGTGCTCC 
GACAAGGAGT TCCGCTGTAG TGACGGAAGC TGCATTGCTG AGCATTGGTA CTGCGACGGT 
GACACCGACT GCAAAGATGG CTCCGATGAG GAGAACTGTC CCTCAGCAGT GCCAGCGCCC 
CCCTGCAACC TGGAGGAGTT CCAGTGTGCC TATGGACGCT GCATCCTCGA CATCTACCAC 
TGCGATGGCG ACGATGACTG TGGAGACTGG TCAGACGAGT CTGACTGCTC CTCCCACCAG 
CCCTGCCGCT CTGGGGAGTT CATGTGTGAC AGTGGCCTGT GCATCAATGC AGGCTGGCGC 
TGCGATGGTG ACGCGGACTG TGATGACCAG TCTGATGAGC GCAACTGCAC CACCTCCATG 
TGTACGGCAG AACAGTTCCG CTGTCACTCA GGCCGCTGTG TCCGCCTGTC CTGGCGCTGT 
GATGGGGAGG ACGACTGTGC AGACAACAGC GATGAAGAGA ACTGTGAGAA TACAGGAAGC 
CCCCAATGTG CCTTGGACCA GTTCCTGTGT TGGAATGGGC GCTGCATTGG GCAGAGGAAG 
CTGTGCAACG GGGTCAACGA CTGTGGTGAC AACAGCGACG AAAGCCCACA GCAGAATTGC 
CGGCCCCGGA CGGGTGAGGA GAACTGCAAT GTTAACAACG GTGGCTGTGC CCAGAAGTGC 
CAGATGGTGC GGGGGGCAGT GCAGTGTACC TGCCACACAG GCTACCGGCT CACAGAGGAT 
GGGCACACGT GCCAAGATGT GAATGAATGT GCCGAGGAGG GGTATTGCAG CCAGGGCTGC 
ACCAACAGCG AAGGGGCTTT CCAATGCTGG TGTGAAACAG GCTATGAACT ACGGCCCGAC 
CGGCGCAGCT GCAAGGCTCT GGGGCCAGAG CCTGTGCTGC TGTTCGCCAA TCGCATCGAC 
ATCCGGCAGG TGCTGCCACA CCGCTCTGAG TACACACTGC TGCTTAACAA CCTGGAGAAT 
GCCATTGCCC TTGATTTCCA CCACCGCCGC GAGCTTGTCT TCTGGTCAGA TGTCACCCTG 
GACCGGATCC TCCGTGCCAA CCTCAACGGC AGCAACGTGG AGGAGGTTGT GTCTACTGGG 
CTGGAGAGCC CAGGGGGCCT GGCTGTGGAT TGGGTCCATG ACAAACTCTA CTGGACCGAC 
TCAGGCACCT CGAGGATTGA GGTGGCCAAT CTGGATGGGG CCCACCGGAA AGTGTTGCTG 
TGGCAGAACC TGGAGAAGCC CCGGGCCATT GCCTTGCATC CCATGGAGGG TACCATTTAC 
TGGACAGACT GGGGCAACAC CCCCCGTATT GAGGCCTCCA GCATGGATGG CTCTGGACGC 
CGCATCATTG CCGATACCCA TCTCTTCTGG CCCAATGGCC TCACCATCGA CTATGCCGGG 
CGCCGTATGT ACTGGGTGGA TGCTAAGCAC CATGTCATCG AGAGGGCCAA TCTGGATGGG 
AGTCACCGTA AGGCTGTCAT TAGCCAGGGC CTCCCGCATC CCTTCGCCAT CACAGTGTTT 
GAAGACAGCC TGTACTGGAC AGACTGGCAC ACCAAGAGCA TCAATAGCGC TAACAAATTT 
ACGGGGAAGA ACCAGGAAAT CATTCGCAAC AAACTCCACT TCCCTATGGA CATCCACACC 
TTGCACCCCC AGCGCCAACC TGCAGGGAAA AACCGCTGTG GGGACAACAA CGGAGGCTGC 
ACGCACCTGT GTCTGCCCAG TGGCCAGAAC TACACCTGTG CCTGCCCCAC TGGCTTCCGC 
AAGATCAGCA GCCACGCCTG TGCCCAGAGT CTTGACAAGT TCCTGCTTTT TGCCCGAAGG 
ATGGACATCC GTCGAATCAG CTTTGACACA GAGGACCTGT CTGATGATGT CATCCCACTG 
GCTGACGTGC GCAGTGCTGT GGCCCTTGAC TGGGACTCCC GGGATGACCA CGTGTACTGG 
ACAGATGTCA GCACTGATAC CATCAGCAGG GCCAAGTGGG ATGGAACAGG ACAGGAGGTG 
GTAGTGGATA CCAGTTTGGA GAGCCCAGCT GGCCTGGCCA TTGATTGGGT CACCAACAAA 
CTGTACTGGA CAGATGCAGG TACAGACCGG ATTGAAGTAG CCAACACAGA TGGCAGCATG 
AGAACAGTAC TCATCTGGGA GAACCTTGAT CGTCCTCGGG ACATCGTGGT GGAACCCATG 
GGCGGGTACA TGTATTGGAC TGACTGGGGT GCGAGCCCCA AGATTGAACG AGCTGGCATG 
GATGCCTCAG GCCGCCAAGT CATTATCTCT TCTAATCTGA CCTGGCCTAA TGGGTTAGCT 
ATTGATTATG GGTCCCAGCG TCTATACTGG GCTGACGCCG GCATGAAGAC AATTGAATTT 
GCTGGACTGG ATGGCAGTAA GAGGAAGGTG CTGATTGGAA GCCAGCTCCC CCACCCATTT 
GGGCTGACCC TCTATGGAGA GCGCATCTAT TGGACTGACT GGCAGACCAA GAGCATACAG 
AGCGCTGACC GGCTGACAGG GCTGGACCGG GAGACTCTGC AGGAGAACCT GGAAAACCTA 
ATGGACATCC ATGTCTTCCA CCGCCGCCGG CCCCCAGTGT CTACACCATG TGCTATGGAG 
AATGGCGGCT GTAGCCACCT GTGTCTTAGG TCCCCAAATC CAAGCGGATT CAGCTGTACC 
TGCCCCACAG GCATCAACCT GCTGTCTGAT GGCAAGACCT GCTCACCAGG CATGAACAGT 
TTCCTCATCT TCGCCAGGAG GATAGACATT CGCATGGTCT CCCTGGACAT CCCTTATTTT 
GCTGATGTGG TGGTACCAAT CAACATTACC ATGAAGAACA CCATTGCCAT TGGAGTAGAC 
CCCCAGGAAG GAAAGGTGTA CTGGTCTGAC AGCACACTGC ACAGGATCAG TCGTGCCAAT 
CTGGATGGCT CACAGCATGA GGACATCATC ACCACAGGGC TACAGACCAC AGATGGGCTC 
GCGGTTGATG CCATTGGCCG GAAAGTATAC TGGACAGACA CGGGAACAAA CCGGATTGAA 
GTGGGCAACC TGGACGGGTC CATGCGGAAA GTGTTGGTGT GGCAGAACCT TGACAGTCCC 
CGGGCCATCG TACTGTACCA TGAGATGGGG TTTATGTACT GGACAGACTG GGGGGAGAAT 
GCCAAGTTAG AGCGGTCCGG AATGGATGGC TCAGACCGCG CGGTGCTCAT CAACAACAAC 
CTAGGATGGC CCAATGGACT GACTGTGGAC AAGGCCAGCT CCCAACTGCT ATGGGCCGAT 
GCCCACACCG AGCGAATTGA GGCTGCTGAC CTGAATGGTG CCAATCGGCA TACATTGGTG 
TCACCGGTGC AGCACCCATA TGGCCTCACC CTGCTCGACT CCTATATCTA CTGGACTGAC 
TGGCAGACTC GGAGCATCCA CCGTGCTGAC AAGGGTACTG GCAGCAATGT CATCCTCGTG 
AGGTCCAACC TGCCAGGCCT CATGGACATG CAGGCTGTGG ACCGGGCACA GCCACTAGGT 
TTTAACAAGT GCGGCTCGAG AAATGGCGGC TGCTCCCACC TCTGCTTGCC TCGGCCTTCT 
GGCTTCTCCT GTGCCTGCCC CACTGGCATC CAGCTGAAGG GAGATGGGAA GACCTGTGAT 
CCCTCTCCTG AGACCTACCT GCTCTTCTCC AGCCGTGGCT CCATCCGGCG TATCTCACTG 
GACACCAGTG ACCACACCGA TGTGCATGTC CCTGTTCCTG AGCTCAACAA TGTCATCTCC 
CTGGACTATG ACAGCGTGGA TGGAAAGGTC TATTACACAG ATGTGTTCCT GGATGTTATC 
AGGCGAGCAG ACCTGAACGG CAGCAACATG GAGACAGTGA TCGGGCGAGG GCTGAAGACC 
ACTGACGGGC TGGCAGTGGA CTGGGTGGCC AGGAACCTGT ACTGGACAGA CACAGGTCGA 
AATACCATTG AGGCGTCCAG GCTGGATGGT TCCTGCCGCA AAGTACTGAT CAACAATAGC 
CTGGATGAGC CCCGGGCCAT TGCTGTTTTC CCCAGGAAGG GGTACCTCTT CTGGACAGAC 
TGGGGCCACA TTGCCAAGAT CGAACGGGCA AACTTGGATG GTTCTGAGCG GAAGGTCCTC 
ATCAACACAG ACCTGGGTTG GCCCAATGGC CTTACCCTGG ACTATGATAC CCGCAGGATC 
TACTGGGTGG ATGCGCATCT GGACCGGATC GAGAGTGCTG ACCTCAATGG GAAACTGCGG 
CAGGTCTTGG TCAGCCATGT GTCCCACCCC TTTGCCCTCA CACAGCAAGA CAGGTGGATC 
TACTGGACAG ACTGGCAGAC CAAGTCAATC CAGCGTGTTG ACAAATACTC AGGCCGGAAC 
AAGGAGACAG TGCTGGCAAA TGTGGAAGGA CTCATGGATA TCATCGTGGT TTCCCCTCAG 
CGGCAGACAG GGACCAATGC CTGTGGTGTG AACAATGGTG GCTGCACCCA CCTCTGCTTT 
GCCAGAGCCT CGGACTTCGT ATGTGCCTGT CCTGACGAAC CTGATAGCCG GCCCTGCTCC 
CTTGTGCCTG GCCTGGTACC ACCAGCTCCT AGGGCTACTG GCATGAGTGA AAAGAGCCCA 
GTGCTACCCA ACACACCACC TACCACCTTG TATTCTTCAA CCACCCGGAC CCGCACGTCT 
CTGGAGGAGG TGGAAGGAAG ATGCTCTGAA AGGGATGCCA GGCTGGGCCT CTGTGCACGT 
TCCAATGACG CTGTTCCTGC TGCTCCAGGG GAAGGACTTC ATATCAGCTA CGCCATTGGT 
GGACTCCTCA GTATTCTGCT GATTTTGGTG GTGATTGCAG CTTTGATGCT GTACAGACAC 
AAAAAATCCA AGTTCACTGA TCCTGGAATG GGGAACCTCA CCTACAGCAA CCCCTCCTAC 
CGAACATCCA CACAGGAAGT GAAGATTGAA GCAATCCCCA AACCAGCCAT GTACAACCAG 
CTGTGCTATA AGAAAGAGGG AGGGCCTGAC CATAACTACA CCAAGGAGAA GATCAAGATC 
GTAGAGGGAA TCTGCCTCCT GTCTGGGGAT GATGCTGAGT GGGATGACCT CAAGCAACTG 
CGAAGCTCAC GGGGGGGCCT CCTCCGGGAT CATGTATGCA TGAAGACAGA CACGGTGTCC 
ATCCAGGCCA GCTCTGGCTC CCTGGATGAC ACAGAGACGG AGCAGCTGTT ACAGGAAGAG 
CAGTCTGAGT GTAGCAGCGT CCATACTGCA GCCACTCCAG AAAGACGAGG CTCTCTGCCA 
GACACGGGCT GGAAACATGA ACGCAAGCTC TCCTCAGAGA GCCAGGTCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_011518404.1

Translation

MSLSKRATEEKTSPGRFSKPTKLSWPLGIGNKRDHGTEISRNMACQFHSRIIQLVKGTLVGERSKQNLGRTKRLPCKREDSCSLQHWLGLASSPECACGRSHFTCAVSALGECTCIPAQWQCDGDNDCGDHSDEDGCILPTCSPLDFHCDNGKCIRRSWVCDGDNDCEDDSDEQDCPPRECEEDEFPCQNGYCIRSLWHCDGDNDCGDNSDEQCDMRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEENCPSAVPAPPCNLEEFQCAYGRCILDIYHCDGDDDCGDWSDESDCSSHQPCRSGEFMCDSGLCINAGWRCDGDADCDDQSDERNCTTSMCTAEQFRCHSGRCVRLSWRCDGEDDCADNSDEENCENTGSPQCALDQFLCWNGRCIGQRKLCNGVNDCGDNSDESPQQNCRPRTGEENCNVNNGGCAQKCQMVRGAVQCTCHTGYRLTEDGHTCQDVNECAEEGYCSQGCTNSEGAFQCWCETGYELRPDRRSCKALGPEPVLLFANRIDIRQVLPHRSEYTLLLNNLENAIALDFHHRRELVFWSDVTLDRILRANLNGSNVEEVVSTGLESPGGLAVDWVHDKLYWTDSGTSRIEVANLDGAHRKVLLWQNLEKPRAIALHPMEGTIYWTDWGNTPRIEASSMDGSGRRIIADTHLFWPNGLTIDYAGRRMYWVDAKHHVIERANLDGSHRKAVISQGLPHPFAITVFEDSLYWTDWHTKSINSANKFTGKNQEIIRNKLHFPMDIHTLHPQRQPAGKNRCGDNNGGCTHLCLPSGQNYTCACPTGFRKISSHACAQSLDKFLLFARRMDIRRISFDTEDLSDDVIPLADVRSAVALDWDSRDDHVYWTDVSTDTISRAKWDGTGQEVVVDTSLESPAGLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWENLDRPRDIVVEPMGGYMYWTDWGASPKIERAGMDASGRQVIISSNLTWPNGLAIDYGSQRLYWADAGMKTIEFAGLDGSKRKVLIGSQLPHPFGLTLYGERIYWTDWQTKSIQSADRLTGLDRETLQENLENLMDIHVFHRRRPPVSTPCAMENGGCSHLCLRSPNPSGFSCTCPTGINLLSDGKTCSPGMNSFLIFARRIDIRMVSLDIPYFADVVVPINITMKNTIAIGVDPQEGKVYWSDSTLHRISRANLDGSQHEDIITTGLQTTDGLAVDAIGRKVYWTDTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIVLYHEMGFMYWTDWGENAKLERSGMDGSDRAVLINNNLGWPNGLTVDKASSQLLWADAHTERIEAADLNGANRHTLVSPVQHPYGLTLLDSYIYWTDWQTRSIHRADKGTGSNVILVRSNLPGLMDMQAVDRAQPLGFNKCGSRNGGCSHLCLPRPSGFSCACPTGIQLKGDGKTCDPSPETYLLFSSRGSIRRISLDTSDHTDVHVPVPELNNVISLDYDSVDGKVYYTDVFLDVIRRADLNGSNMETVIGRGLKTTDGLAVDWVARNLYWTDTGRNTIEASRLDGSCRKVLINNSLDEPRAIAVFPRKGYLFWTDWGHIAKIERANLDGSERKVLINTDLGWPNGLTLDYDTRRIYWVDAHLDRIESADLNGKLRQVLVSHVSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGRNKETVLANVEGLMDIIVVSPQRQTGTNACGVNNGGCTHLCFARASDFVCACPDEPDSRPCSLVPGLVPPAPRATGMSEKSPVLPNTPPTTLYSSTTRTRTSLEEVEGRCSERDARLGLCARSNDAVPAAPGEGLHISYAIGGLLSILLILVVIAALMLYRHKKSKFTDPGMGNLTYSNPSYRTSTQEVKIEAIPKPAMYNQLCYKKEGGPDHNYTKEKIKIVEGICLLSGDDAEWDDLKQLRSSRGGLLRDHVCMKTDTVSIQASSGSLDDTETEQLLQEEQSECSSVHTAATPERRGSLPDTGWKHERKLSSESQV

Target ORF information:

RefSeq Version	XM_011520102.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens low density lipoprotein receptor-related protein 4 (LRP4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011520102.1

ORF Insert Sequence:

ATGTCCCTTT CGAAACGGGC CACTGAGGAG AAGACTTCAC CTGGTAGATT TTCCAAACCA 
ACCAAGTTAA GCTGGCCTCT AGGAATCGGG AATAAAAGGG ACCATGGGAC AGAAATAAGT 
AGAAACATGG CGTGTCAGTT TCACAGCCGG ATAATACAGC TGGTGAAAGG AACTCTTGTA 
GGAGAAAGGA GTAAACAAAA CCTGGGTAGG ACAAAGAGGC TGCCTTGCAA ACGAGAAGAT 
TCCTGTTCTC TCCAGCACTG GTTAGGCCTG GCCAGCAGCC CCGAGTGTGC TTGTGGTCGG 
AGCCACTTCA CATGTGCAGT GAGTGCTCTT GGAGAGTGTA CCTGCATCCC TGCCCAGTGG 
CAGTGTGATG GAGACAATGA CTGCGGGGAC CACAGCGATG AGGATGGATG TATACTACCT 
ACCTGTTCCC CTCTTGACTT TCACTGTGAC AATGGCAAGT GCATCCGCCG CTCCTGGGTG 
TGTGACGGGG ACAACGACTG TGAGGATGAC TCGGATGAGC AGGACTGTCC CCCCCGGGAG 
TGTGAGGAGG ACGAGTTTCC CTGCCAGAAT GGCTACTGCA TCCGGAGTCT GTGGCACTGC 
GATGGTGACA ATGACTGTGG CGACAACAGC GATGAGCAGT GTGACATGCG CAAGTGCTCC 
GACAAGGAGT TCCGCTGTAG TGACGGAAGC TGCATTGCTG AGCATTGGTA CTGCGACGGT 
GACACCGACT GCAAAGATGG CTCCGATGAG GAGAACTGTC CCTCAGCAGT GCCAGCGCCC 
CCCTGCAACC TGGAGGAGTT CCAGTGTGCC TATGGACGCT GCATCCTCGA CATCTACCAC 
TGCGATGGCG ACGATGACTG TGGAGACTGG TCAGACGAGT CTGACTGCTC CTCCCACCAG 
CCCTGCCGCT CTGGGGAGTT CATGTGTGAC AGTGGCCTGT GCATCAATGC AGGCTGGCGC 
TGCGATGGTG ACGCGGACTG TGATGACCAG TCTGATGAGC GCAACTGCAC CACCTCCATG 
TGTACGGCAG AACAGTTCCG CTGTCACTCA GGCCGCTGTG TCCGCCTGTC CTGGCGCTGT 
GATGGGGAGG ACGACTGTGC AGACAACAGC GATGAAGAGA ACTGTGAGAA TACAGGAAGC 
CCCCAATGTG CCTTGGACCA GTTCCTGTGT TGGAATGGGC GCTGCATTGG GCAGAGGAAG 
CTGTGCAACG GGGTCAACGA CTGTGGTGAC AACAGCGACG AAAGCCCACA GCAGAATTGC 
CGGCCCCGGA CGGGTGAGGA GAACTGCAAT GTTAACAACG GTGGCTGTGC CCAGAAGTGC 
CAGATGGTGC GGGGGGCAGT GCAGTGTACC TGCCACACAG GCTACCGGCT CACAGAGGAT 
GGGCACACGT GCCAAGATGT GAATGAATGT GCCGAGGAGG GGTATTGCAG CCAGGGCTGC 
ACCAACAGCG AAGGGGCTTT CCAATGCTGG TGTGAAACAG GCTATGAACT ACGGCCCGAC 
CGGCGCAGCT GCAAGGCTCT GGGGCCAGAG CCTGTGCTGC TGTTCGCCAA TCGCATCGAC 
ATCCGGCAGG TGCTGCCACA CCGCTCTGAG TACACACTGC TGCTTAACAA CCTGGAGAAT 
GCCATTGCCC TTGATTTCCA CCACCGCCGC GAGCTTGTCT TCTGGTCAGA TGTCACCCTG 
GACCGGATCC TCCGTGCCAA CCTCAACGGC AGCAACGTGG AGGAGGTTGT GTCTACTGGG 
CTGGAGAGCC CAGGGGGCCT GGCTGTGGAT TGGGTCCATG ACAAACTCTA CTGGACCGAC 
TCAGGCACCT CGAGGATTGA GGTGGCCAAT CTGGATGGGG CCCACCGGAA AGTGTTGCTG 
TGGCAGAACC TGGAGAAGCC CCGGGCCATT GCCTTGCATC CCATGGAGGG TACCATTTAC 
TGGACAGACT GGGGCAACAC CCCCCGTATT GAGGCCTCCA GCATGGATGG CTCTGGACGC 
CGCATCATTG CCGATACCCA TCTCTTCTGG CCCAATGGCC TCACCATCGA CTATGCCGGG 
CGCCGTATGT ACTGGGTGGA TGCTAAGCAC CATGTCATCG AGAGGGCCAA TCTGGATGGG 
AGTCACCGTA AGGCTGTCAT TAGCCAGGGC CTCCCGCATC CCTTCGCCAT CACAGTGTTT 
GAAGACAGCC TGTACTGGAC AGACTGGCAC ACCAAGAGCA TCAATAGCGC TAACAAATTT 
ACGGGGAAGA ACCAGGAAAT CATTCGCAAC AAACTCCACT TCCCTATGGA CATCCACACC 
TTGCACCCCC AGCGCCAACC TGCAGGGAAA AACCGCTGTG GGGACAACAA CGGAGGCTGC 
ACGCACCTGT GTCTGCCCAG TGGCCAGAAC TACACCTGTG CCTGCCCCAC TGGCTTCCGC 
AAGATCAGCA GCCACGCCTG TGCCCAGAGT CTTGACAAGT TCCTGCTTTT TGCCCGAAGG 
ATGGACATCC GTCGAATCAG CTTTGACACA GAGGACCTGT CTGATGATGT CATCCCACTG 
GCTGACGTGC GCAGTGCTGT GGCCCTTGAC TGGGACTCCC GGGATGACCA CGTGTACTGG 
ACAGATGTCA GCACTGATAC CATCAGCAGG GCCAAGTGGG ATGGAACAGG ACAGGAGGTG 
GTAGTGGATA CCAGTTTGGA GAGCCCAGCT GGCCTGGCCA TTGATTGGGT CACCAACAAA 
CTGTACTGGA CAGATGCAGG TACAGACCGG ATTGAAGTAG CCAACACAGA TGGCAGCATG 
AGAACAGTAC TCATCTGGGA GAACCTTGAT CGTCCTCGGG ACATCGTGGT GGAACCCATG 
GGCGGGTACA TGTATTGGAC TGACTGGGGT GCGAGCCCCA AGATTGAACG AGCTGGCATG 
GATGCCTCAG GCCGCCAAGT CATTATCTCT TCTAATCTGA CCTGGCCTAA TGGGTTAGCT 
ATTGATTATG GGTCCCAGCG TCTATACTGG GCTGACGCCG GCATGAAGAC AATTGAATTT 
GCTGGACTGG ATGGCAGTAA GAGGAAGGTG CTGATTGGAA GCCAGCTCCC CCACCCATTT 
GGGCTGACCC TCTATGGAGA GCGCATCTAT TGGACTGACT GGCAGACCAA GAGCATACAG 
AGCGCTGACC GGCTGACAGG GCTGGACCGG GAGACTCTGC AGGAGAACCT GGAAAACCTA 
ATGGACATCC ATGTCTTCCA CCGCCGCCGG CCCCCAGTGT CTACACCATG TGCTATGGAG 
AATGGCGGCT GTAGCCACCT GTGTCTTAGG TCCCCAAATC CAAGCGGATT CAGCTGTACC 
TGCCCCACAG GCATCAACCT GCTGTCTGAT GGCAAGACCT GCTCACCAGG CATGAACAGT 
TTCCTCATCT TCGCCAGGAG GATAGACATT CGCATGGTCT CCCTGGACAT CCCTTATTTT 
GCTGATGTGG TGGTACCAAT CAACATTACC ATGAAGAACA CCATTGCCAT TGGAGTAGAC 
CCCCAGGAAG GAAAGGTGTA CTGGTCTGAC AGCACACTGC ACAGGATCAG TCGTGCCAAT 
CTGGATGGCT CACAGCATGA GGACATCATC ACCACAGGGC TACAGACCAC AGATGGGCTC 
GCGGTTGATG CCATTGGCCG GAAAGTATAC TGGACAGACA CGGGAACAAA CCGGATTGAA 
GTGGGCAACC TGGACGGGTC CATGCGGAAA GTGTTGGTGT GGCAGAACCT TGACAGTCCC 
CGGGCCATCG TACTGTACCA TGAGATGGGG TTTATGTACT GGACAGACTG GGGGGAGAAT 
GCCAAGTTAG AGCGGTCCGG AATGGATGGC TCAGACCGCG CGGTGCTCAT CAACAACAAC 
CTAGGATGGC CCAATGGACT GACTGTGGAC AAGGCCAGCT CCCAACTGCT ATGGGCCGAT 
GCCCACACCG AGCGAATTGA GGCTGCTGAC CTGAATGGTG CCAATCGGCA TACATTGGTG 
TCACCGGTGC AGCACCCATA TGGCCTCACC CTGCTCGACT CCTATATCTA CTGGACTGAC 
TGGCAGACTC GGAGCATCCA CCGTGCTGAC AAGGGTACTG GCAGCAATGT CATCCTCGTG 
AGGTCCAACC TGCCAGGCCT CATGGACATG CAGGCTGTGG ACCGGGCACA GCCACTAGGT 
TTTAACAAGT GCGGCTCGAG AAATGGCGGC TGCTCCCACC TCTGCTTGCC TCGGCCTTCT 
GGCTTCTCCT GTGCCTGCCC CACTGGCATC CAGCTGAAGG GAGATGGGAA GACCTGTGAT 
CCCTCTCCTG AGACCTACCT GCTCTTCTCC AGCCGTGGCT CCATCCGGCG TATCTCACTG 
GACACCAGTG ACCACACCGA TGTGCATGTC CCTGTTCCTG AGCTCAACAA TGTCATCTCC 
CTGGACTATG ACAGCGTGGA TGGAAAGGTC TATTACACAG ATGTGTTCCT GGATGTTATC 
AGGCGAGCAG ACCTGAACGG CAGCAACATG GAGACAGTGA TCGGGCGAGG GCTGAAGACC 
ACTGACGGGC TGGCAGTGGA CTGGGTGGCC AGGAACCTGT ACTGGACAGA CACAGGTCGA 
AATACCATTG AGGCGTCCAG GCTGGATGGT TCCTGCCGCA AAGTACTGAT CAACAATAGC 
CTGGATGAGC CCCGGGCCAT TGCTGTTTTC CCCAGGAAGG GGTACCTCTT CTGGACAGAC 
TGGGGCCACA TTGCCAAGAT CGAACGGGCA AACTTGGATG GTTCTGAGCG GAAGGTCCTC 
ATCAACACAG ACCTGGGTTG GCCCAATGGC CTTACCCTGG ACTATGATAC CCGCAGGATC 
TACTGGGTGG ATGCGCATCT GGACCGGATC GAGAGTGCTG ACCTCAATGG GAAACTGCGG 
CAGGTCTTGG TCAGCCATGT GTCCCACCCC TTTGCCCTCA CACAGCAAGA CAGGTGGATC 
TACTGGACAG ACTGGCAGAC CAAGTCAATC CAGCGTGTTG ACAAATACTC AGGCCGGAAC 
AAGGAGACAG TGCTGGCAAA TGTGGAAGGA CTCATGGATA TCATCGTGGT TTCCCCTCAG 
CGGCAGACAG GGACCAATGC CTGTGGTGTG AACAATGGTG GCTGCACCCA CCTCTGCTTT 
GCCAGAGCCT CGGACTTCGT ATGTGCCTGT CCTGACGAAC CTGATAGCCG GCCCTGCTCC 
CTTGTGCCTG GCCTGGTACC ACCAGCTCCT AGGGCTACTG GCATGAGTGA AAAGAGCCCA 
GTGCTACCCA ACACACCACC TACCACCTTG TATTCTTCAA CCACCCGGAC CCGCACGTCT 
CTGGAGGAGG TGGAAGGAAG ATGCTCTGAA AGGGATGCCA GGCTGGGCCT CTGTGCACGT 
TCCAATGACG CTGTTCCTGC TGCTCCAGGG GAAGGACTTC ATATCAGCTA CGCCATTGGT 
GGACTCCTCA GTATTCTGCT GATTTTGGTG GTGATTGCAG CTTTGATGCT GTACAGACAC 
AAAAAATCCA AGTTCACTGA TCCTGGAATG GGGAACCTCA CCTACAGCAA CCCCTCCTAC 
CGAACATCCA CACAGGAAGT GAAGATTGAA GCAATCCCCA AACCAGCCAT GTACAACCAG 
CTGTGCTATA AGAAAGAGGG AGGGCCTGAC CATAACTACA CCAAGGAGAA GATCAAGATC 
GTAGAGGGAA TCTGCCTCCT GTCTGGGGAT GATGCTGAGT GGGATGACCT CAAGCAACTG 
CGAAGCTCAC GGGGGGGCCT CCTCCGGGAT CATGTATGCA TGAAGACAGA CACGGTGTCC 
ATCCAGGCCA GCTCTGGCTC CCTGGATGAC ACAGAGACGG AGCAGCTGTT ACAGGAAGAG 
CAGTCTGAGT GTAGCAGCGT CCATACTGCA GCCACTCCAG AAAGACGAGG CTCTCTGCCA 
GACACGGGCT GGAAACATGA ACGCAAGCTC TCCTCAGAGA GCCAGGTCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRP4 ( XM_011520103.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011518405.1 Homo sapiens LDL receptor related protein 4 (LRP4), transcript variant X2, mRNA.

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CloneID	OHu58775
Clone ID Related Accession (Same CDS sequence)	XM_011520103.2
Accession Version	XM_011520103.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4914bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	low-density lipoprotein receptor-related protein 4 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011520103.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGTACGG CAGAACAGTT CCGCTGTCAC TCAGGCCGCT GTGTCCGCCT GTCCTGGCGC 
TGTGATGGGG AGGACGACTG TGCAGACAAC AGCGATGAAG AGAACTGTGA GAATACAGGA 
AGCCCCCAAT GTGCCTTGGA CCAGTTCCTG TGTTGGAATG GGCGCTGCAT TGGGCAGAGG 
AAGCTGTGCA ACGGGGTCAA CGACTGTGGT GACAACAGCG ACGAAAGCCC ACAGCAGAAT 
TGCCGGCCCC GGACGGGTGA GGAGAACTGC AATGTTAACA ACGGTGGCTG TGCCCAGAAG 
TGCCAGATGG TGCGGGGGGC AGTGCAGTGT ACCTGCCACA CAGGCTACCG GCTCACAGAG 
GATGGGCACA CGTGCCAAGA TGTGAATGAA TGTGCCGAGG AGGGGTATTG CAGCCAGGGC 
TGCACCAACA GCGAAGGGGC TTTCCAATGC TGGTGTGAAA CAGGCTATGA ACTACGGCCC 
GACCGGCGCA GCTGCAAGGC TCTGGGGCCA GAGCCTGTGC TGCTGTTCGC CAATCGCATC 
GACATCCGGC AGGTGCTGCC ACACCGCTCT GAGTACACAC TGCTGCTTAA CAACCTGGAG 
AATGCCATTG CCCTTGATTT CCACCACCGC CGCGAGCTTG TCTTCTGGTC AGATGTCACC 
CTGGACCGGA TCCTCCGTGC CAACCTCAAC GGCAGCAACG TGGAGGAGGT TGTGTCTACT 
GGGCTGGAGA GCCCAGGGGG CCTGGCTGTG GATTGGGTCC ATGACAAACT CTACTGGACC 
GACTCAGGCA CCTCGAGGAT TGAGGTGGCC AATCTGGATG GGGCCCACCG GAAAGTGTTG 
CTGTGGCAGA ACCTGGAGAA GCCCCGGGCC ATTGCCTTGC ATCCCATGGA GGGTACCATT 
TACTGGACAG ACTGGGGCAA CACCCCCCGT ATTGAGGCCT CCAGCATGGA TGGCTCTGGA 
CGCCGCATCA TTGCCGATAC CCATCTCTTC TGGCCCAATG GCCTCACCAT CGACTATGCC 
GGGCGCCGTA TGTACTGGGT GGATGCTAAG CACCATGTCA TCGAGAGGGC CAATCTGGAT 
GGGAGTCACC GTAAGGCTGT CATTAGCCAG GGCCTCCCGC ATCCCTTCGC CATCACAGTG 
TTTGAAGACA GCCTGTACTG GACAGACTGG CACACCAAGA GCATCAATAG CGCTAACAAA 
TTTACGGGGA AGAACCAGGA AATCATTCGC AACAAACTCC ACTTCCCTAT GGACATCCAC 
ACCTTGCACC CCCAGCGCCA ACCTGCAGGG AAAAACCGCT GTGGGGACAA CAACGGAGGC 
TGCACGCACC TGTGTCTGCC CAGTGGCCAG AACTACACCT GTGCCTGCCC CACTGGCTTC 
CGCAAGATCA GCAGCCACGC CTGTGCCCAG AGTCTTGACA AGTTCCTGCT TTTTGCCCGA 
AGGATGGACA TCCGTCGAAT CAGCTTTGAC ACAGAGGACC TGTCTGATGA TGTCATCCCA 
CTGGCTGACG TGCGCAGTGC TGTGGCCCTT GACTGGGACT CCCGGGATGA CCACGTGTAC 
TGGACAGATG TCAGCACTGA TACCATCAGC AGGGCCAAGT GGGATGGAAC AGGACAGGAG 
GTGGTAGTGG ATACCAGTTT GGAGAGCCCA GCTGGCCTGG CCATTGATTG GGTCACCAAC 
AAACTGTACT GGACAGATGC AGGTACAGAC CGGATTGAAG TAGCCAACAC AGATGGCAGC 
ATGAGAACAG TACTCATCTG GGAGAACCTT GATCGTCCTC GGGACATCGT GGTGGAACCC 
ATGGGCGGGT ACATGTATTG GACTGACTGG GGTGCGAGCC CCAAGATTGA ACGAGCTGGC 
ATGGATGCCT CAGGCCGCCA AGTCATTATC TCTTCTAATC TGACCTGGCC TAATGGGTTA 
GCTATTGATT ATGGGTCCCA GCGTCTATAC TGGGCTGACG CCGGCATGAA GACAATTGAA 
TTTGCTGGAC TGGATGGCAG TAAGAGGAAG GTGCTGATTG GAAGCCAGCT CCCCCACCCA 
TTTGGGCTGA CCCTCTATGG AGAGCGCATC TATTGGACTG ACTGGCAGAC CAAGAGCATA 
CAGAGCGCTG ACCGGCTGAC AGGGCTGGAC CGGGAGACTC TGCAGGAGAA CCTGGAAAAC 
CTAATGGACA TCCATGTCTT CCACCGCCGC CGGCCCCCAG TGTCTACACC ATGTGCTATG 
GAGAATGGCG GCTGTAGCCA CCTGTGTCTT AGGTCCCCAA ATCCAAGCGG ATTCAGCTGT 
ACCTGCCCCA CAGGCATCAA CCTGCTGTCT GATGGCAAGA CCTGCTCACC AGGCATGAAC 
AGTTTCCTCA TCTTCGCCAG GAGGATAGAC ATTCGCATGG TCTCCCTGGA CATCCCTTAT 
TTTGCTGATG TGGTGGTACC AATCAACATT ACCATGAAGA ACACCATTGC CATTGGAGTA 
GACCCCCAGG AAGGAAAGGT GTACTGGTCT GACAGCACAC TGCACAGGAT CAGTCGTGCC 
AATCTGGATG GCTCACAGCA TGAGGACATC ATCACCACAG GGCTACAGAC CACAGATGGG 
CTCGCGGTTG ATGCCATTGG CCGGAAAGTA TACTGGACAG ACACGGGAAC AAACCGGATT 
GAAGTGGGCA ACCTGGACGG GTCCATGCGG AAAGTGTTGG TGTGGCAGAA CCTTGACAGT 
CCCCGGGCCA TCGTACTGTA CCATGAGATG GGGTTTATGT ACTGGACAGA CTGGGGGGAG 
AATGCCAAGT TAGAGCGGTC CGGAATGGAT GGCTCAGACC GCGCGGTGCT CATCAACAAC 
AACCTAGGAT GGCCCAATGG ACTGACTGTG GACAAGGCCA GCTCCCAACT GCTATGGGCC 
GATGCCCACA CCGAGCGAAT TGAGGCTGCT GACCTGAATG GTGCCAATCG GCATACATTG 
GTGTCACCGG TGCAGCACCC ATATGGCCTC ACCCTGCTCG ACTCCTATAT CTACTGGACT 
GACTGGCAGA CTCGGAGCAT CCACCGTGCT GACAAGGGTA CTGGCAGCAA TGTCATCCTC 
GTGAGGTCCA ACCTGCCAGG CCTCATGGAC ATGCAGGCTG TGGACCGGGC ACAGCCACTA 
GGTTTTAACA AGTGCGGCTC GAGAAATGGC GGCTGCTCCC ACCTCTGCTT GCCTCGGCCT 
TCTGGCTTCT CCTGTGCCTG CCCCACTGGC ATCCAGCTGA AGGGAGATGG GAAGACCTGT 
GATCCCTCTC CTGAGACCTA CCTGCTCTTC TCCAGCCGTG GCTCCATCCG GCGTATCTCA 
CTGGACACCA GTGACCACAC CGATGTGCAT GTCCCTGTTC CTGAGCTCAA CAATGTCATC 
TCCCTGGACT ATGACAGCGT GGATGGAAAG GTCTATTACA CAGATGTGTT CCTGGATGTT 
ATCAGGCGAG CAGACCTGAA CGGCAGCAAC ATGGAGACAG TGATCGGGCG AGGGCTGAAG 
ACCACTGACG GGCTGGCAGT GGACTGGGTG GCCAGGAACC TGTACTGGAC AGACACAGGT 
CGAAATACCA TTGAGGCGTC CAGGCTGGAT GGTTCCTGCC GCAAAGTACT GATCAACAAT 
AGCCTGGATG AGCCCCGGGC CATTGCTGTT TTCCCCAGGA AGGGGTACCT CTTCTGGACA 
GACTGGGGCC ACATTGCCAA GATCGAACGG GCAAACTTGG ATGGTTCTGA GCGGAAGGTC 
CTCATCAACA CAGACCTGGG TTGGCCCAAT GGCCTTACCC TGGACTATGA TACCCGCAGG 
ATCTACTGGG TGGATGCGCA TCTGGACCGG ATCGAGAGTG CTGACCTCAA TGGGAAACTG 
CGGCAGGTCT TGGTCAGCCA TGTGTCCCAC CCCTTTGCCC TCACACAGCA AGACAGGTGG 
ATCTACTGGA CAGACTGGCA GACCAAGTCA ATCCAGCGTG TTGACAAATA CTCAGGCCGG 
AACAAGGAGA CAGTGCTGGC AAATGTGGAA GGACTCATGG ATATCATCGT GGTTTCCCCT 
CAGCGGCAGA CAGGGACCAA TGCCTGTGGT GTGAACAATG GTGGCTGCAC CCACCTCTGC 
TTTGCCAGAG CCTCGGACTT CGTATGTGCC TGTCCTGACG AACCTGATAG CCGGCCCTGC 
TCCCTTGTGC CTGGCCTGGT ACCACCAGCT CCTAGGGCTA CTGGCATGAG TGAAAAGAGC 
CCAGTGCTAC CCAACACACC ACCTACCACC TTGTATTCTT CAACCACCCG GACCCGCACG 
TCTCTGGAGG AGGTGGAAGG AAGATGCTCT GAAAGGGATG CCAGGCTGGG CCTCTGTGCA 
CGTTCCAATG ACGCTGTTCC TGCTGCTCCA GGGGAAGGAC TTCATATCAG CTACGCCATT 
GGTGGACTCC TCAGTATTCT GCTGATTTTG GTGGTGATTG CAGCTTTGAT GCTGTACAGA 
CACAAAAAAT CCAAGTTCAC TGATCCTGGA ATGGGGAACC TCACCTACAG CAACCCCTCC 
TACCGAACAT CCACACAGGA AGTGAAGATT GAAGCAATCC CCAAACCAGC CATGTACAAC 
CAGCTGTGCT ATAAGAAAGA GGGAGGGCCT GACCATAACT ACACCAAGGA GAAGATCAAG 
ATCGTAGAGG GAATCTGCCT CCTGTCTGGG GATGATGCTG AGTGGGATGA CCTCAAGCAA 
CTGCGAAGCT CACGGGGGGG CCTCCTCCGG GATCATGTAT GCATGAAGAC AGACACGGTG 
TCCATCCAGG CCAGCTCTGG CTCCCTGGAT GACACAGAGA CGGAGCAGCT GTTACAGGAA 
GAGCAGTCTG AGTGTAGCAG CGTCCATACT GCAGCCACTC CAGAAAGACG AGGCTCTCTG 
CCAGACACGG GCTGGAAACA TGAACGCAAG CTCTCCTCAG AGAGCCAGGT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011518405.1
CDS	118..5031
Translation	MCTAEQFRCHSGRCVRLSWRCDGEDDCADNSDEENCENTGSPQCALDQFLCWNGRCIGQRKLCNGVNDCGDNSDESPQQNCRPRTGEENCNVNNGGCAQKCQMVRGAVQCTCHTGYRLTEDGHTCQDVNECAEEGYCSQGCTNSEGAFQCWCETGYELRPDRRSCKALGPEPVLLFANRIDIRQVLPHRSEYTLLLNNLENAIALDFHHRRELVFWSDVTLDRILRANLNGSNVEEVVSTGLESPGGLAVDWVHDKLYWTDSGTSRIEVANLDGAHRKVLLWQNLEKPRAIALHPMEGTIYWTDWGNTPRIEASSMDGSGRRIIADTHLFWPNGLTIDYAGRRMYWVDAKHHVIERANLDGSHRKAVISQGLPHPFAITVFEDSLYWTDWHTKSINSANKFTGKNQEIIRNKLHFPMDIHTLHPQRQPAGKNRCGDNNGGCTHLCLPSGQNYTCACPTGFRKISSHACAQSLDKFLLFARRMDIRRISFDTEDLSDDVIPLADVRSAVALDWDSRDDHVYWTDVSTDTISRAKWDGTGQEVVVDTSLESPAGLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWENLDRPRDIVVEPMGGYMYWTDWGASPKIERAGMDASGRQVIISSNLTWPNGLAIDYGSQRLYWADAGMKTIEFAGLDGSKRKVLIGSQLPHPFGLTLYGERIYWTDWQTKSIQSADRLTGLDRETLQENLENLMDIHVFHRRRPPVSTPCAMENGGCSHLCLRSPNPSGFSCTCPTGINLLSDGKTCSPGMNSFLIFARRIDIRMVSLDIPYFADVVVPINITMKNTIAIGVDPQEGKVYWSDSTLHRISRANLDGSQHEDIITTGLQTTDGLAVDAIGRKVYWTDTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIVLYHEMGFMYWTDWGENAKLERSGMDGSDRAVLINNNLGWPNGLTVDKASSQLLWADAHTERIEAADLNGANRHTLVSPVQHPYGLTLLDSYIYWTDWQTRSIHRADKGTGSNVILVRSNLPGLMDMQAVDRAQPLGFNKCGSRNGGCSHLCLPRPSGFSCACPTGIQLKGDGKTCDPSPETYLLFSSRGSIRRISLDTSDHTDVHVPVPELNNVISLDYDSVDGKVYYTDVFLDVIRRADLNGSNMETVIGRGLKTTDGLAVDWVARNLYWTDTGRNTIEASRLDGSCRKVLINNSLDEPRAIAVFPRKGYLFWTDWGHIAKIERANLDGSERKVLINTDLGWPNGLTLDYDTRRIYWVDAHLDRIESADLNGKLRQVLVSHVSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGRNKETVLANVEGLMDIIVVSPQRQTGTNACGVNNGGCTHLCFARASDFVCACPDEPDSRPCSLVPGLVPPAPRATGMSEKSPVLPNTPPTTLYSSTTRTRTSLEEVEGRCSERDARLGLCARSNDAVPAAPGEGLHISYAIGGLLSILLILVVIAALMLYRHKKSKFTDPGMGNLTYSNPSYRTSTQEVKIEAIPKPAMYNQLCYKKEGGPDHNYTKEKIKIVEGICLLSGDDAEWDDLKQLRSSRGGLLRDHVCMKTDTVSIQASSGSLDDTETEQLLQEEQSECSSVHTAATPERRGSLPDTGWKHERKLSSESQV

Target ORF information:

RefSeq Version	XM_011520103.2
Organism	Homo sapiens(human)
Definition	Homo sapiens LDL receptor related protein 4 (LRP4), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011520103.2

ORF Insert Sequence:

ATGTGTACGG CAGAACAGTT CCGCTGTCAC TCAGGCCGCT GTGTCCGCCT GTCCTGGCGC 
TGTGATGGGG AGGACGACTG TGCAGACAAC AGCGATGAAG AGAACTGTGA GAATACAGGA 
AGCCCCCAAT GTGCCTTGGA CCAGTTCCTG TGTTGGAATG GGCGCTGCAT TGGGCAGAGG 
AAGCTGTGCA ACGGGGTCAA CGACTGTGGT GACAACAGCG ACGAAAGCCC ACAGCAGAAT 
TGCCGGCCCC GGACGGGTGA GGAGAACTGC AATGTTAACA ACGGTGGCTG TGCCCAGAAG 
TGCCAGATGG TGCGGGGGGC AGTGCAGTGT ACCTGCCACA CAGGCTACCG GCTCACAGAG 
GATGGGCACA CGTGCCAAGA TGTGAATGAA TGTGCCGAGG AGGGGTATTG CAGCCAGGGC 
TGCACCAACA GCGAAGGGGC TTTCCAATGC TGGTGTGAAA CAGGCTATGA ACTACGGCCC 
GACCGGCGCA GCTGCAAGGC TCTGGGGCCA GAGCCTGTGC TGCTGTTCGC CAATCGCATC 
GACATCCGGC AGGTGCTGCC ACACCGCTCT GAGTACACAC TGCTGCTTAA CAACCTGGAG 
AATGCCATTG CCCTTGATTT CCACCACCGC CGCGAGCTTG TCTTCTGGTC AGATGTCACC 
CTGGACCGGA TCCTCCGTGC CAACCTCAAC GGCAGCAACG TGGAGGAGGT TGTGTCTACT 
GGGCTGGAGA GCCCAGGGGG CCTGGCTGTG GATTGGGTCC ATGACAAACT CTACTGGACC 
GACTCAGGCA CCTCGAGGAT TGAGGTGGCC AATCTGGATG GGGCCCACCG GAAAGTGTTG 
CTGTGGCAGA ACCTGGAGAA GCCCCGGGCC ATTGCCTTGC ATCCCATGGA GGGTACCATT 
TACTGGACAG ACTGGGGCAA CACCCCCCGT ATTGAGGCCT CCAGCATGGA TGGCTCTGGA 
CGCCGCATCA TTGCCGATAC CCATCTCTTC TGGCCCAATG GCCTCACCAT CGACTATGCC 
GGGCGCCGTA TGTACTGGGT GGATGCTAAG CACCATGTCA TCGAGAGGGC CAATCTGGAT 
GGGAGTCACC GTAAGGCTGT CATTAGCCAG GGCCTCCCGC ATCCCTTCGC CATCACAGTG 
TTTGAAGACA GCCTGTACTG GACAGACTGG CACACCAAGA GCATCAATAG CGCTAACAAA 
TTTACGGGGA AGAACCAGGA AATCATTCGC AACAAACTCC ACTTCCCTAT GGACATCCAC 
ACCTTGCACC CCCAGCGCCA ACCTGCAGGG AAAAACCGCT GTGGGGACAA CAACGGAGGC 
TGCACGCACC TGTGTCTGCC CAGTGGCCAG AACTACACCT GTGCCTGCCC CACTGGCTTC 
CGCAAGATCA GCAGCCACGC CTGTGCCCAG AGTCTTGACA AGTTCCTGCT TTTTGCCCGA 
AGGATGGACA TCCGTCGAAT CAGCTTTGAC ACAGAGGACC TGTCTGATGA TGTCATCCCA 
CTGGCTGACG TGCGCAGTGC TGTGGCCCTT GACTGGGACT CCCGGGATGA CCACGTGTAC 
TGGACAGATG TCAGCACTGA TACCATCAGC AGGGCCAAGT GGGATGGAAC AGGACAGGAG 
GTGGTAGTGG ATACCAGTTT GGAGAGCCCA GCTGGCCTGG CCATTGATTG GGTCACCAAC 
AAACTGTACT GGACAGATGC AGGTACAGAC CGGATTGAAG TAGCCAACAC AGATGGCAGC 
ATGAGAACAG TACTCATCTG GGAGAACCTT GATCGTCCTC GGGACATCGT GGTGGAACCC 
ATGGGCGGGT ACATGTATTG GACTGACTGG GGTGCGAGCC CCAAGATTGA ACGAGCTGGC 
ATGGATGCCT CAGGCCGCCA AGTCATTATC TCTTCTAATC TGACCTGGCC TAATGGGTTA 
GCTATTGATT ATGGGTCCCA GCGTCTATAC TGGGCTGACG CCGGCATGAA GACAATTGAA 
TTTGCTGGAC TGGATGGCAG TAAGAGGAAG GTGCTGATTG GAAGCCAGCT CCCCCACCCA 
TTTGGGCTGA CCCTCTATGG AGAGCGCATC TATTGGACTG ACTGGCAGAC CAAGAGCATA 
CAGAGCGCTG ACCGGCTGAC AGGGCTGGAC CGGGAGACTC TGCAGGAGAA CCTGGAAAAC 
CTAATGGACA TCCATGTCTT CCACCGCCGC CGGCCCCCAG TGTCTACACC ATGTGCTATG 
GAGAATGGCG GCTGTAGCCA CCTGTGTCTT AGGTCCCCAA ATCCAAGCGG ATTCAGCTGT 
ACCTGCCCCA CAGGCATCAA CCTGCTGTCT GATGGCAAGA CCTGCTCACC AGGCATGAAC 
AGTTTCCTCA TCTTCGCCAG GAGGATAGAC ATTCGCATGG TCTCCCTGGA CATCCCTTAT 
TTTGCTGATG TGGTGGTACC AATCAACATT ACCATGAAGA ACACCATTGC CATTGGAGTA 
GACCCCCAGG AAGGAAAGGT GTACTGGTCT GACAGCACAC TGCACAGGAT CAGTCGTGCC 
AATCTGGATG GCTCACAGCA TGAGGACATC ATCACCACAG GGCTACAGAC CACAGATGGG 
CTCGCGGTTG ATGCCATTGG CCGGAAAGTA TACTGGACAG ACACGGGAAC AAACCGGATT 
GAAGTGGGCA ACCTGGACGG GTCCATGCGG AAAGTGTTGG TGTGGCAGAA CCTTGACAGT 
CCCCGGGCCA TCGTACTGTA CCATGAGATG GGGTTTATGT ACTGGACAGA CTGGGGGGAG 
AATGCCAAGT TAGAGCGGTC CGGAATGGAT GGCTCAGACC GCGCGGTGCT CATCAACAAC 
AACCTAGGAT GGCCCAATGG ACTGACTGTG GACAAGGCCA GCTCCCAACT GCTATGGGCC 
GATGCCCACA CCGAGCGAAT TGAGGCTGCT GACCTGAATG GTGCCAATCG GCATACATTG 
GTGTCACCGG TGCAGCACCC ATATGGCCTC ACCCTGCTCG ACTCCTATAT CTACTGGACT 
GACTGGCAGA CTCGGAGCAT CCACCGTGCT GACAAGGGTA CTGGCAGCAA TGTCATCCTC 
GTGAGGTCCA ACCTGCCAGG CCTCATGGAC ATGCAGGCTG TGGACCGGGC ACAGCCACTA 
GGTTTTAACA AGTGCGGCTC GAGAAATGGC GGCTGCTCCC ACCTCTGCTT GCCTCGGCCT 
TCTGGCTTCT CCTGTGCCTG CCCCACTGGC ATCCAGCTGA AGGGAGATGG GAAGACCTGT 
GATCCCTCTC CTGAGACCTA CCTGCTCTTC TCCAGCCGTG GCTCCATCCG GCGTATCTCA 
CTGGACACCA GTGACCACAC CGATGTGCAT GTCCCTGTTC CTGAGCTCAA CAATGTCATC 
TCCCTGGACT ATGACAGCGT GGATGGAAAG GTCTATTACA CAGATGTGTT CCTGGATGTT 
ATCAGGCGAG CAGACCTGAA CGGCAGCAAC ATGGAGACAG TGATCGGGCG AGGGCTGAAG 
ACCACTGACG GGCTGGCAGT GGACTGGGTG GCCAGGAACC TGTACTGGAC AGACACAGGT 
CGAAATACCA TTGAGGCGTC CAGGCTGGAT GGTTCCTGCC GCAAAGTACT GATCAACAAT 
AGCCTGGATG AGCCCCGGGC CATTGCTGTT TTCCCCAGGA AGGGGTACCT CTTCTGGACA 
GACTGGGGCC ACATTGCCAA GATCGAACGG GCAAACTTGG ATGGTTCTGA GCGGAAGGTC 
CTCATCAACA CAGACCTGGG TTGGCCCAAT GGCCTTACCC TGGACTATGA TACCCGCAGG 
ATCTACTGGG TGGATGCGCA TCTGGACCGG ATCGAGAGTG CTGACCTCAA TGGGAAACTG 
CGGCAGGTCT TGGTCAGCCA TGTGTCCCAC CCCTTTGCCC TCACACAGCA AGACAGGTGG 
ATCTACTGGA CAGACTGGCA GACCAAGTCA ATCCAGCGTG TTGACAAATA CTCAGGCCGG 
AACAAGGAGA CAGTGCTGGC AAATGTGGAA GGACTCATGG ATATCATCGT GGTTTCCCCT 
CAGCGGCAGA CAGGGACCAA TGCCTGTGGT GTGAACAATG GTGGCTGCAC CCACCTCTGC 
TTTGCCAGAG CCTCGGACTT CGTATGTGCC TGTCCTGACG AACCTGATAG CCGGCCCTGC 
TCCCTTGTGC CTGGCCTGGT ACCACCAGCT CCTAGGGCTA CTGGCATGAG TGAAAAGAGC 
CCAGTGCTAC CCAACACACC ACCTACCACC TTGTATTCTT CAACCACCCG GACCCGCACG 
TCTCTGGAGG AGGTGGAAGG AAGATGCTCT GAAAGGGATG CCAGGCTGGG CCTCTGTGCA 
CGTTCCAATG ACGCTGTTCC TGCTGCTCCA GGGGAAGGAC TTCATATCAG CTACGCCATT 
GGTGGACTCC TCAGTATTCT GCTGATTTTG GTGGTGATTG CAGCTTTGAT GCTGTACAGA 
CACAAAAAAT CCAAGTTCAC TGATCCTGGA ATGGGGAACC TCACCTACAG CAACCCCTCC 
TACCGAACAT CCACACAGGA AGTGAAGATT GAAGCAATCC CCAAACCAGC CATGTACAAC 
CAGCTGTGCT ATAAGAAAGA GGGAGGGCCT GACCATAACT ACACCAAGGA GAAGATCAAG 
ATCGTAGAGG GAATCTGCCT CCTGTCTGGG GATGATGCTG AGTGGGATGA CCTCAAGCAA 
CTGCGAAGCT CACGGGGGGG CCTCCTCCGG GATCATGTAT GCATGAAGAC AGACACGGTG 
TCCATCCAGG CCAGCTCTGG CTCCCTGGAT GACACAGAGA CGGAGCAGCT GTTACAGGAA 
GAGCAGTCTG AGTGTAGCAG CGTCCATACT GCAGCCACTC CAGAAAGACG AGGCTCTCTG 
CCAGACACGG GCTGGAAACA TGAACGCAAG CTCTCCTCAG AGAGCCAGGT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRP4 ( XM_011520104.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011518406.1 Homo sapiens LDL receptor related protein 4 (LRP4), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu58776
Clone ID Related Accession (Same CDS sequence)	XM_011520104.2
Accession Version	XM_011520104.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3483bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	low-density lipoprotein receptor-related protein 4 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011520104.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCACGCA GGATGGACAT CCGTCGAATC AGCTTTGACA CAGAGGACCT GTCTGATGAT 
GTCATCCCAC TGGCTGACGT GCGCAGTGCT GTGGCCCTTG ACTGGGACTC CCGGGATGAC 
CACGTGTACT GGACAGATGT CAGCACTGAT ACCATCAGCA GGGCCAAGTG GGATGGAACA 
GGACAGGAGG TGGTAGTGGA TACCAGTTTG GAGAGCCCAG CTGGCCTGGC CATTGATTGG 
GTCACCAACA AACTGTACTG GACAGATGCA GGTACAGACC GGATTGAAGT AGCCAACACA 
GATGGCAGCA TGAGAACAGT ACTCATCTGG GAGAACCTTG ATCGTCCTCG GGACATCGTG 
GTGGAACCCA TGGGCGGGTA CATGTATTGG ACTGACTGGG GTGCGAGCCC CAAGATTGAA 
CGAGCTGGCA TGGATGCCTC AGGCCGCCAA GTCATTATCT CTTCTAATCT GACCTGGCCT 
AATGGGTTAG CTATTGATTA TGGGTCCCAG CGTCTATACT GGGCTGACGC CGGCATGAAG 
ACAATTGAAT TTGCTGGACT GGATGGCAGT AAGAGGAAGG TGCTGATTGG AAGCCAGCTC 
CCCCACCCAT TTGGGCTGAC CCTCTATGGA GAGCGCATCT ATTGGACTGA CTGGCAGACC 
AAGAGCATAC AGAGCGCTGA CCGGCTGACA GGGCTGGACC GGGAGACTCT GCAGGAGAAC 
CTGGAAAACC TAATGGACAT CCATGTCTTC CACCGCCGCC GGCCCCCAGT GTCTACACCA 
TGTGCTATGG AGAATGGCGG CTGTAGCCAC CTGTGTCTTA GGTCCCCAAA TCCAAGCGGA 
TTCAGCTGTA CCTGCCCCAC AGGCATCAAC CTGCTGTCTG ATGGCAAGAC CTGCTCACCA 
GGCATGAACA GTTTCCTCAT CTTCGCCAGG AGGATAGACA TTCGCATGGT CTCCCTGGAC 
ATCCCTTATT TTGCTGATGT GGTGGTACCA ATCAACATTA CCATGAAGAA CACCATTGCC 
ATTGGAGTAG ACCCCCAGGA AGGAAAGGTG TACTGGTCTG ACAGCACACT GCACAGGATC 
AGTCGTGCCA ATCTGGATGG CTCACAGCAT GAGGACATCA TCACCACAGG GCTACAGACC 
ACAGATGGGC TCGCGGTTGA TGCCATTGGC CGGAAAGTAT ACTGGACAGA CACGGGAACA 
AACCGGATTG AAGTGGGCAA CCTGGACGGG TCCATGCGGA AAGTGTTGGT GTGGCAGAAC 
CTTGACAGTC CCCGGGCCAT CGTACTGTAC CATGAGATGG GGTTTATGTA CTGGACAGAC 
TGGGGGGAGA ATGCCAAGTT AGAGCGGTCC GGAATGGATG GCTCAGACCG CGCGGTGCTC 
ATCAACAACA ACCTAGGATG GCCCAATGGA CTGACTGTGG ACAAGGCCAG CTCCCAACTG 
CTATGGGCCG ATGCCCACAC CGAGCGAATT GAGGCTGCTG ACCTGAATGG TGCCAATCGG 
CATACATTGG TGTCACCGGT GCAGCACCCA TATGGCCTCA CCCTGCTCGA CTCCTATATC 
TACTGGACTG ACTGGCAGAC TCGGAGCATC CACCGTGCTG ACAAGGGTAC TGGCAGCAAT 
GTCATCCTCG TGAGGTCCAA CCTGCCAGGC CTCATGGACA TGCAGGCTGT GGACCGGGCA 
CAGCCACTAG GTTTTAACAA GTGCGGCTCG AGAAATGGCG GCTGCTCCCA CCTCTGCTTG 
CCTCGGCCTT CTGGCTTCTC CTGTGCCTGC CCCACTGGCA TCCAGCTGAA GGGAGATGGG 
AAGACCTGTG ATCCCTCTCC TGAGACCTAC CTGCTCTTCT CCAGCCGTGG CTCCATCCGG 
CGTATCTCAC TGGACACCAG TGACCACACC GATGTGCATG TCCCTGTTCC TGAGCTCAAC 
AATGTCATCT CCCTGGACTA TGACAGCGTG GATGGAAAGG TCTATTACAC AGATGTGTTC 
CTGGATGTTA TCAGGCGAGC AGACCTGAAC GGCAGCAACA TGGAGACAGT GATCGGGCGA 
GGGCTGAAGA CCACTGACGG GCTGGCAGTG GACTGGGTGG CCAGGAACCT GTACTGGACA 
GACACAGGTC GAAATACCAT TGAGGCGTCC AGGCTGGATG GTTCCTGCCG CAAAGTACTG 
ATCAACAATA GCCTGGATGA GCCCCGGGCC ATTGCTGTTT TCCCCAGGAA GGGGTACCTC 
TTCTGGACAG ACTGGGGCCA CATTGCCAAG ATCGAACGGG CAAACTTGGA TGGTTCTGAG 
CGGAAGGTCC TCATCAACAC AGACCTGGGT TGGCCCAATG GCCTTACCCT GGACTATGAT 
ACCCGCAGGA TCTACTGGGT GGATGCGCAT CTGGACCGGA TCGAGAGTGC TGACCTCAAT 
GGGAAACTGC GGCAGGTCTT GGTCAGCCAT GTGTCCCACC CCTTTGCCCT CACACAGCAA 
GACAGGTGGA TCTACTGGAC AGACTGGCAG ACCAAGTCAA TCCAGCGTGT TGACAAATAC 
TCAGGCCGGA ACAAGGAGAC AGTGCTGGCA AATGTGGAAG GACTCATGGA TATCATCGTG 
GTTTCCCCTC AGCGGCAGAC AGGGACCAAT GCCTGTGGTG TGAACAATGG TGGCTGCACC 
CACCTCTGCT TTGCCAGAGC CTCGGACTTC GTATGTGCCT GTCCTGACGA ACCTGATAGC 
CGGCCCTGCT CCCTTGTGCC TGGCCTGGTA CCACCAGCTC CTAGGGCTAC TGGCATGAGT 
GAAAAGAGCC CAGTGCTACC CAACACACCA CCTACCACCT TGTATTCTTC AACCACCCGG 
ACCCGCACGT CTCTGGAGGA GGTGGAAGGA AGATGCTCTG AAAGGGATGC CAGGCTGGGC 
CTCTGTGCAC GTTCCAATGA CGCTGTTCCT GCTGCTCCAG GGGAAGGACT TCATATCAGC 
TACGCCATTG GTGGACTCCT CAGTATTCTG CTGATTTTGG TGGTGATTGC AGCTTTGATG 
CTGTACAGAC ACAAAAAATC CAAGTTCACT GATCCTGGAA TGGGGAACCT CACCTACAGC 
AACCCCTCCT ACCGAACATC CACACAGGAA GTGAAGATTG AAGCAATCCC CAAACCAGCC 
ATGTACAACC AGCTGTGCTA TAAGAAAGAG GGAGGGCCTG ACCATAACTA CACCAAGGAG 
AAGATCAAGA TCGTAGAGGG AATCTGCCTC CTGTCTGGGG ATGATGCTGA GTGGGATGAC 
CTCAAGCAAC TGCGAAGCTC ACGGGGGGGC CTCCTCCGGG ATCATGTATG CATGAAGACA 
GACACGGTGT CCATCCAGGC CAGCTCTGGC TCCCTGGATG ACACAGAGAC GGAGCAGCTG 
TTACAGGAAG AGCAGTCTGA GTGTAGCAGC GTCCATACTG CAGCCACTCC AGAAAGACGA 
GGCTCTCTGC CAGACACGGG CTGGAAACAT GAACGCAAGC TCTCCTCAGA GAGCCAGGTC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011518406.1
CDS	16..3498
Translation	MSRRMDIRRISFDTEDLSDDVIPLADVRSAVALDWDSRDDHVYWTDVSTDTISRAKWDGTGQEVVVDTSLESPAGLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWENLDRPRDIVVEPMGGYMYWTDWGASPKIERAGMDASGRQVIISSNLTWPNGLAIDYGSQRLYWADAGMKTIEFAGLDGSKRKVLIGSQLPHPFGLTLYGERIYWTDWQTKSIQSADRLTGLDRETLQENLENLMDIHVFHRRRPPVSTPCAMENGGCSHLCLRSPNPSGFSCTCPTGINLLSDGKTCSPGMNSFLIFARRIDIRMVSLDIPYFADVVVPINITMKNTIAIGVDPQEGKVYWSDSTLHRISRANLDGSQHEDIITTGLQTTDGLAVDAIGRKVYWTDTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIVLYHEMGFMYWTDWGENAKLERSGMDGSDRAVLINNNLGWPNGLTVDKASSQLLWADAHTERIEAADLNGANRHTLVSPVQHPYGLTLLDSYIYWTDWQTRSIHRADKGTGSNVILVRSNLPGLMDMQAVDRAQPLGFNKCGSRNGGCSHLCLPRPSGFSCACPTGIQLKGDGKTCDPSPETYLLFSSRGSIRRISLDTSDHTDVHVPVPELNNVISLDYDSVDGKVYYTDVFLDVIRRADLNGSNMETVIGRGLKTTDGLAVDWVARNLYWTDTGRNTIEASRLDGSCRKVLINNSLDEPRAIAVFPRKGYLFWTDWGHIAKIERANLDGSERKVLINTDLGWPNGLTLDYDTRRIYWVDAHLDRIESADLNGKLRQVLVSHVSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGRNKETVLANVEGLMDIIVVSPQRQTGTNACGVNNGGCTHLCFARASDFVCACPDEPDSRPCSLVPGLVPPAPRATGMSEKSPVLPNTPPTTLYSSTTRTRTSLEEVEGRCSERDARLGLCARSNDAVPAAPGEGLHISYAIGGLLSILLILVVIAALMLYRHKKSKFTDPGMGNLTYSNPSYRTSTQEVKIEAIPKPAMYNQLCYKKEGGPDHNYTKEKIKIVEGICLLSGDDAEWDDLKQLRSSRGGLLRDHVCMKTDTVSIQASSGSLDDTETEQLLQEEQSECSSVHTAATPERRGSLPDTGWKHERKLSSESQV

Target ORF information:

RefSeq Version	XM_011520104.2
Organism	Homo sapiens(human)
Definition	Homo sapiens LDL receptor related protein 4 (LRP4), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011520104.2

ORF Insert Sequence:

ATGTCACGCA GGATGGACAT CCGTCGAATC AGCTTTGACA CAGAGGACCT GTCTGATGAT 
GTCATCCCAC TGGCTGACGT GCGCAGTGCT GTGGCCCTTG ACTGGGACTC CCGGGATGAC 
CACGTGTACT GGACAGATGT CAGCACTGAT ACCATCAGCA GGGCCAAGTG GGATGGAACA 
GGACAGGAGG TGGTAGTGGA TACCAGTTTG GAGAGCCCAG CTGGCCTGGC CATTGATTGG 
GTCACCAACA AACTGTACTG GACAGATGCA GGTACAGACC GGATTGAAGT AGCCAACACA 
GATGGCAGCA TGAGAACAGT ACTCATCTGG GAGAACCTTG ATCGTCCTCG GGACATCGTG 
GTGGAACCCA TGGGCGGGTA CATGTATTGG ACTGACTGGG GTGCGAGCCC CAAGATTGAA 
CGAGCTGGCA TGGATGCCTC AGGCCGCCAA GTCATTATCT CTTCTAATCT GACCTGGCCT 
AATGGGTTAG CTATTGATTA TGGGTCCCAG CGTCTATACT GGGCTGACGC CGGCATGAAG 
ACAATTGAAT TTGCTGGACT GGATGGCAGT AAGAGGAAGG TGCTGATTGG AAGCCAGCTC 
CCCCACCCAT TTGGGCTGAC CCTCTATGGA GAGCGCATCT ATTGGACTGA CTGGCAGACC 
AAGAGCATAC AGAGCGCTGA CCGGCTGACA GGGCTGGACC GGGAGACTCT GCAGGAGAAC 
CTGGAAAACC TAATGGACAT CCATGTCTTC CACCGCCGCC GGCCCCCAGT GTCTACACCA 
TGTGCTATGG AGAATGGCGG CTGTAGCCAC CTGTGTCTTA GGTCCCCAAA TCCAAGCGGA 
TTCAGCTGTA CCTGCCCCAC AGGCATCAAC CTGCTGTCTG ATGGCAAGAC CTGCTCACCA 
GGCATGAACA GTTTCCTCAT CTTCGCCAGG AGGATAGACA TTCGCATGGT CTCCCTGGAC 
ATCCCTTATT TTGCTGATGT GGTGGTACCA ATCAACATTA CCATGAAGAA CACCATTGCC 
ATTGGAGTAG ACCCCCAGGA AGGAAAGGTG TACTGGTCTG ACAGCACACT GCACAGGATC 
AGTCGTGCCA ATCTGGATGG CTCACAGCAT GAGGACATCA TCACCACAGG GCTACAGACC 
ACAGATGGGC TCGCGGTTGA TGCCATTGGC CGGAAAGTAT ACTGGACAGA CACGGGAACA 
AACCGGATTG AAGTGGGCAA CCTGGACGGG TCCATGCGGA AAGTGTTGGT GTGGCAGAAC 
CTTGACAGTC CCCGGGCCAT CGTACTGTAC CATGAGATGG GGTTTATGTA CTGGACAGAC 
TGGGGGGAGA ATGCCAAGTT AGAGCGGTCC GGAATGGATG GCTCAGACCG CGCGGTGCTC 
ATCAACAACA ACCTAGGATG GCCCAATGGA CTGACTGTGG ACAAGGCCAG CTCCCAACTG 
CTATGGGCCG ATGCCCACAC CGAGCGAATT GAGGCTGCTG ACCTGAATGG TGCCAATCGG 
CATACATTGG TGTCACCGGT GCAGCACCCA TATGGCCTCA CCCTGCTCGA CTCCTATATC 
TACTGGACTG ACTGGCAGAC TCGGAGCATC CACCGTGCTG ACAAGGGTAC TGGCAGCAAT 
GTCATCCTCG TGAGGTCCAA CCTGCCAGGC CTCATGGACA TGCAGGCTGT GGACCGGGCA 
CAGCCACTAG GTTTTAACAA GTGCGGCTCG AGAAATGGCG GCTGCTCCCA CCTCTGCTTG 
CCTCGGCCTT CTGGCTTCTC CTGTGCCTGC CCCACTGGCA TCCAGCTGAA GGGAGATGGG 
AAGACCTGTG ATCCCTCTCC TGAGACCTAC CTGCTCTTCT CCAGCCGTGG CTCCATCCGG 
CGTATCTCAC TGGACACCAG TGACCACACC GATGTGCATG TCCCTGTTCC TGAGCTCAAC 
AATGTCATCT CCCTGGACTA TGACAGCGTG GATGGAAAGG TCTATTACAC AGATGTGTTC 
CTGGATGTTA TCAGGCGAGC AGACCTGAAC GGCAGCAACA TGGAGACAGT GATCGGGCGA 
GGGCTGAAGA CCACTGACGG GCTGGCAGTG GACTGGGTGG CCAGGAACCT GTACTGGACA 
GACACAGGTC GAAATACCAT TGAGGCGTCC AGGCTGGATG GTTCCTGCCG CAAAGTACTG 
ATCAACAATA GCCTGGATGA GCCCCGGGCC ATTGCTGTTT TCCCCAGGAA GGGGTACCTC 
TTCTGGACAG ACTGGGGCCA CATTGCCAAG ATCGAACGGG CAAACTTGGA TGGTTCTGAG 
CGGAAGGTCC TCATCAACAC AGACCTGGGT TGGCCCAATG GCCTTACCCT GGACTATGAT 
ACCCGCAGGA TCTACTGGGT GGATGCGCAT CTGGACCGGA TCGAGAGTGC TGACCTCAAT 
GGGAAACTGC GGCAGGTCTT GGTCAGCCAT GTGTCCCACC CCTTTGCCCT CACACAGCAA 
GACAGGTGGA TCTACTGGAC AGACTGGCAG ACCAAGTCAA TCCAGCGTGT TGACAAATAC 
TCAGGCCGGA ACAAGGAGAC AGTGCTGGCA AATGTGGAAG GACTCATGGA TATCATCGTG 
GTTTCCCCTC AGCGGCAGAC AGGGACCAAT GCCTGTGGTG TGAACAATGG TGGCTGCACC 
CACCTCTGCT TTGCCAGAGC CTCGGACTTC GTATGTGCCT GTCCTGACGA ACCTGATAGC 
CGGCCCTGCT CCCTTGTGCC TGGCCTGGTA CCACCAGCTC CTAGGGCTAC TGGCATGAGT 
GAAAAGAGCC CAGTGCTACC CAACACACCA CCTACCACCT TGTATTCTTC AACCACCCGG 
ACCCGCACGT CTCTGGAGGA GGTGGAAGGA AGATGCTCTG AAAGGGATGC CAGGCTGGGC 
CTCTGTGCAC GTTCCAATGA CGCTGTTCCT GCTGCTCCAG GGGAAGGACT TCATATCAGC 
TACGCCATTG GTGGACTCCT CAGTATTCTG CTGATTTTGG TGGTGATTGC AGCTTTGATG 
CTGTACAGAC ACAAAAAATC CAAGTTCACT GATCCTGGAA TGGGGAACCT CACCTACAGC 
AACCCCTCCT ACCGAACATC CACACAGGAA GTGAAGATTG AAGCAATCCC CAAACCAGCC 
ATGTACAACC AGCTGTGCTA TAAGAAAGAG GGAGGGCCTG ACCATAACTA CACCAAGGAG 
AAGATCAAGA TCGTAGAGGG AATCTGCCTC CTGTCTGGGG ATGATGCTGA GTGGGATGAC 
CTCAAGCAAC TGCGAAGCTC ACGGGGGGGC CTCCTCCGGG ATCATGTATG CATGAAGACA 
GACACGGTGT CCATCCAGGC CAGCTCTGGC TCCCTGGATG ACACAGAGAC GGAGCAGCTG 
TTACAGGAAG AGCAGTCTGA GTGTAGCAGC GTCCATACTG CAGCCACTCC AGAAAGACGA 
GGCTCTCTGC CAGACACGGG CTGGAAACAT GAACGCAAGC TCTCCTCAGA GAGCCAGGTC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRP4 ( XM_017017734.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016873223.1 Homo sapiens LDL receptor related protein 4 (LRP4), transcript variant X1, mRNA.

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CloneID	OHu92227
Clone ID Related Accession (Same CDS sequence)	XM_017017734.1
Accession Version	XM_017017734.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5430bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	low-density lipoprotein receptor-related protein 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGGCGGC AGTGGGGCGC GCTGCTGCTT GGCGCCCTGC TCTGCGCACA CGGCCTGGCC 
AGCAGCCCCG AGTGTGCTTG TGGTCGGAGC CACTTCACAT GTGCAGTGAG TGCTCTTGGA 
GAGTGTACCT GCATCCCTGC CCAGTGGCAG TGTGATGGAG ACAATGACTG CGGGGACCAC 
AGCGATGAGG ATGGATGTAT ACTACCTACC TGTTCCCCTC TTGACTTTCA CTGTGACAAT 
GGCAAGTGCA TCCGCCGCTC CTGGGTGTGT GACGGGGACA ACGACTGTGA GGATGACTCG 
GATGAGCAGG ACTGTCCCCC CCGGGAGTGT GAGGAGGACG AGTTTCCCTG CCAGAATGGC 
TACTGCATCC GGAGTCTGTG GCACTGCGAT GGTGACAATG ACTGTGGCGA CAACAGCGAT 
GAGCAGTGTG ACATGCGCAA GTGCTCCGAC AAGGAGTTCC GCTGTAGTGA CGGAAGCTGC 
ATTGCTGAGC ATTGGTACTG CGACGGTGAC ACCGACTGCA AAGATGGCTC CGATGAGGAG 
AACTGTCCCT CAGCAGTGCC AGCGCCCCCC TGCAACCTGG AGGAGTTCCA GTGTGCCTAT 
GGACGCTGCA TCCTCGACAT CTACCACTGC GATGGCGACG ATGACTGTGG AGACTGGTCA 
GACGAGTCTG ACTGCTCCTC CCACCAGCCC TGCCGCTCTG GGGAGTTCAT GTGTGACAGT 
GGCCTGTGCA TCAATGCAGG CTGGCGCTGC GATGGTGACG CGGACTGTGA TGACCAGTCT 
GATGAGCGCA ACTGCACCAC CTCCATGTGT ACGGCAGAAC AGTTCCGCTG TCACTCAGGC 
CGCTGTGTCC GCCTGTCCTG GCGCTGTGAT GGGGAGGACG ACTGTGCAGA CAACAGCGAT 
GAAGAGAACT GTGAGAATAC AGGAAGCCCC CAATGTGCCT TGGACCAGTT CCTGTGTTGG 
AATGGGCGCT GCATTGGGCA GAGGAAGCTG TGCAACGGGG TCAACGACTG TGGTGACAAC 
AGCGACGAAA GCCCACAGCA GAATTGCCGG CCCCGGACGG GTGAGGAGAA CTGCAATGTT 
AACAACGGTG GCTGTGCCCA GAAGTGCCAG ATGGTGCGGG GGGCAGTGCA GTGTACCTGC 
CACACAGGCT ACCGGCTCAC AGAGGATGGG CACACGTGCC AAGATGTGAA TGAATGTGCC 
GAGGAGGGGT ATTGCAGCCA GGGCTGCACC AACAGCGAAG GGGCTTTCCA ATGCTGGTGT 
GAAACAGGCT ATGAACTACG GCCCGACCGG CGCAGCTGCA AGGCTCTGGG GCCAGAGCCT 
GTGCTGCTGT TCGCCAATCG CATCGACATC CGGCAGGTGC TGCCACACCG CTCTGAGTAC 
ACACTGCTGC TTAACAACCT GGAGAATGCC ATTGCCCTTG ATTTCCACCA CCGCCGCGAG 
CTTGTCTTCT GGTCAGATGT CACCCTGGAC CGGATCCTCC GTGCCAACCT CAACGGCAGC 
AACGTGGAGG AGGTTGTGTC TACTGGGCTG GAGAGCCCAG GGGGCCTGGC TGTGGATTGG 
GTCCATGACA AACTCTACTG GACCGACTCA GGCACCTCGA GGATTGAGGT GGCCAATCTG 
GATGGGGCCC ACCGGAAAGT GTTGCTGTGG CAGAACCTGG AGAAGCCCCG GGCCATTGCC 
TTGCATCCCA TGGAGGGTAC CATTTACTGG ACAGACTGGG GCAACACCCC CCGTATTGAG 
GCCTCCAGCA TGGATGGCTC TGGACGCCGC ATCATTGCCG ATACCCATCT CTTCTGGCCC 
AATGGCCTCA CCATCGACTA TGCCGGGCGC CGTATGTACT GGGTGGATGC TAAGCACCAT 
GTCATCGAGA GGGCCAATCT GGATGGGAGT CACCGTAAGG CTGTCATTAG CCAGGGCCTC 
CCGCATCCCT TCGCCATCAC AGTGTTTGAA GACAGCCTGT ACTGGACAGA CTGGCACACC 
AAGAGCATCA ATAGCGCTAA CAAATTTACG GGGAAGAACC AGGAAATCAT TCGCAACAAA 
CTCCACTTCC CTATGGACAT CCACACCTTG CACCCCCAGC GCCAACCTGC AGGGAAAAAC 
CGCTGTGGGG ACAACAACGG AGGCTGCACG CACCTGTGTC TGCCCAGTGG CCAGAACTAC 
ACCTGTGCCT GCCCCACTGG CTTCCGCAAG ATCAGCAGCC ACGCCTGTGC CCAGAGTCTT 
GACAAGTTCC TGCTTTTTGC CCGAAGGATG GACATCCGTC GAATCAGCTT TGACACAGAG 
GACCTGTCTG ATGATGTCAT CCCACTGGCT GACGTGCGCA GTGCTGTGGC CCTTGACTGG 
GACTCCCGGG ATGACCACGT GTACTGGACA GATGTCAGCA CTGATACCAT CAGCAGGGCC 
AAGTGGGATG GAACAGGACA GGAGGTGGTA GTGGATACCA GTTTGGAGAG CCCAGCTGGC 
CTGGCCATTG ATTGGGTCAC CAACAAACTG TACTGGACAG ATGCAGGTAC AGACCGGATT 
GAAGTAGCCA ACACAGATGG CAGCATGAGA ACAGTACTCA TCTGGGAGAA CCTTGATCGT 
CCTCGGGACA TCGTGGTGGA ACCCATGGGC GGGTACATGT ATTGGACTGA CTGGGGTGCG 
AGCCCCAAGA TTGAACGAGC TGGCATGGAT GCCTCAGGCC GCCAAGTCAT TATCTCTTCT 
AATCTGACCT GGCCTAATGG GTTAGCTATT GATTATGGGT CCCAGCGTCT ATACTGGGCT 
GACGCCGGCA TGAAGACAAT TGAATTTGCT GGACTGGATG GCAGTAAGAG GAAGGTGCTG 
ATTGGAAGCC AGCTCCCCCA CCCATTTGGG CTGACCCTCT ATGGAGAGCG CATCTATTGG 
ACTGACTGGC AGACCAAGAG CATACAGAGC GCTGACCGGC TGACAGGGCT GGACCGGGAG 
ACTCTGCAGG AGAACCTGGA AAACCTAATG GACATCCATG TCTTCCACCG CCGCCGGCCC 
CCAGTGTCTA CACCATGTGC TATGGAGAAT GGCGGCTGTA GCCACCTGTG TCTTAGGTCC 
CCAAATCCAA GCGGATTCAG CTGTACCTGC CCCACAGGCA TCAACCTGCT GTCTGATGGC 
AAGACCTGCT CACCAGGCAT GAACAGTTTC CTCATCTTCG CCAGGAGGAT AGACATTCGC 
ATGGTCTCCC TGGACATCCC TTATTTTGCT GATGTGGTGG TACCAATCAA CATTACCATG 
AAGAACACCA TTGCCATTGG AGTAGACCCC CAGGAAGGAA AGGTGTACTG GTCTGACAGC 
ACACTGCACA GGATCAGTCG TGCCAATCTG GATGGCTCAC AGCATGAGGA CATCATCACC 
ACAGGGCTAC AGACCACAGA TGGGCTCGCG GTTGATGCCA TTGGCCGGAA AGTATACTGG 
ACAGACACGG GAACAAACCG GATTGAAGTG GGCAACCTGG ACGGGTCCAT GCGGAAAGTG 
TTGGTGTGGC AGAACCTTGA CAGTCCCCGG GCCATCGTAC TGTACCATGA GATGGGGTTT 
ATGTACTGGA CAGACTGGGG GGAGAATGCC AAGTTAGAGC GGTCCGGAAT GGATGGCTCA 
GACCGCGCGG TGCTCATCAA CAACAACCTA GGATGGCCCA ATGGACTGAC TGTGGACAAG 
GCCAGCTCCC AACTGCTATG GGCCGATGCC CACACCGAGC GAATTGAGGC TGCTGACCTG 
AATGGTGCCA ATCGGCATAC ATTGGTGTCA CCGGTGCAGC ACCCATATGG CCTCACCCTG 
CTCGACTCCT ATATCTACTG GACTGACTGG CAGACTCGGA GCATCCACCG TGCTGACAAG 
GGTACTGGCA GCAATGTCAT CCTCGTGAGG TCCAACCTGC CAGGCCTCAT GGACATGCAG 
GCTGTGGACC GGGCACAGCC ACTAGGTTTT AACAAGTGCG GCTCGAGAAA TGGCGGCTGC 
TCCCACCTCT GCTTGCCTCG GCCTTCTGGC TTCTCCTGTG CCTGCCCCAC TGGCATCCAG 
CTGAAGGGAG ATGGGAAGAC CTGTGATCCC TCTCCTGAGA CCTACCTGCT CTTCTCCAGC 
CGTGGCTCCA TCCGGCGTAT CTCACTGGAC ACCAGTGACC ACACCGATGT GCATGTCCCT 
GTTCCTGAGC TCAACAATGT CATCTCCCTG GACTATGACA GCGTGGATGG AAAGGTCTAT 
TACACAGATG TGTTCCTGGA TGTTATCAGG CGAGCAGACC TGAACGGCAG CAACATGGAG 
ACAGTGATCG GGCGAGGGCT GAAGACCACT GACGGGCTGG CAGTGGACTG GGTGGCCAGG 
AACCTGTACT GGACAGACAC AGGTCGAAAT ACCATTGAGG CGTCCAGGCT GGATGGTTCC 
TGCCGCAAAG TACTGATCAA CAATAGCCTG GATGAGCCCC GGGCCATTGC TGTTTTCCCC 
AGGAAGGGGT ACCTCTTCTG GACAGACTGG GGCCACATTG CCAAGATCGA ACGGGCAAAC 
TTGGATGGTT CTGAGCGGAA GGTCCTCATC AACACAGACC TGGGTTGGCC CAATGGCCTT 
ACCCTGGACT ATGATACCCG CAGGATCTAC TGGGTGGATG CGCATCTGGA CCGGATCGAG 
AGTGCTGACC TCAATGGGAA ACTGCGGCAG GTCTTGGTCA GCCATGTGTC CCACCCCTTT 
GCCCTCACAC AGCAAGACAG GTGGATCTAC TGGACAGACT GGCAGACCAA GTCAATCCAG 
CGTGTTGACA AATACTCAGG CCGGAACAAG GAGACAGTGC TGGCAAATGT GGAAGGACTC 
ATGGATATCA TCGTGGTTTC CCCTCAGCGG CAGACAGGGA CCAATGCCTG TGGTGTGAAC 
AATGGTGGCT GCACCCACCT CTGCTTTGCC AGAGCCTCGG ACTTCGTATG TGCCTGTCCT 
GACGAACCTG ATAGCCGGCC CTGCTCCCTT GTGCCTGGCC TGGTACCACC AGCTCCTAGG 
GCTACTGGCA TGAGTGAAAA GAGCCCAGTG CTACCCAACA CACCACCTAC CACCTTGTAT 
TCTTCAACCA CCCGGACCCG CACGTCTCTG GAGGAGGTGG AAGGAAGATG CTCTGAAAGG 
GATGCCAGGC TGGGCCTCTG TGCACGTTCC AATGACGCTG TTCCTGCTGC TCCAGGGGAA 
GGACTTCATA TCAGCTACGC CATTGGTGGA CTCCTCAGTA TTCTGCTGAT TTTGGTGGTG 
ATTGCAGCTT TGATGCTGTA CAGACACAAA AAATCCAAGT TCACTGATCC TGGAATGGGG 
AACCTCACCT ACAGCAACCC CTCCTACCGA ACATCCACAC AGGAAGTGAA GATTGAAGCA 
ATCCCCAAAC CAGCCATGTA CAACCAGCTG TGCTATAAGA AAGAGCAGCT CTTTCACCCC 
TCTGATAGTC TTTCACCTTT TCTCTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016873223.1
CDS	161..5590
Translation	MRRQWGALLLGALLCAHGLASSPECACGRSHFTCAVSALGECTCIPAQWQCDGDNDCGDHSDEDGCILPTCSPLDFHCDNGKCIRRSWVCDGDNDCEDDSDEQDCPPRECEEDEFPCQNGYCIRSLWHCDGDNDCGDNSDEQCDMRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEENCPSAVPAPPCNLEEFQCAYGRCILDIYHCDGDDDCGDWSDESDCSSHQPCRSGEFMCDSGLCINAGWRCDGDADCDDQSDERNCTTSMCTAEQFRCHSGRCVRLSWRCDGEDDCADNSDEENCENTGSPQCALDQFLCWNGRCIGQRKLCNGVNDCGDNSDESPQQNCRPRTGEENCNVNNGGCAQKCQMVRGAVQCTCHTGYRLTEDGHTCQDVNECAEEGYCSQGCTNSEGAFQCWCETGYELRPDRRSCKALGPEPVLLFANRIDIRQVLPHRSEYTLLLNNLENAIALDFHHRRELVFWSDVTLDRILRANLNGSNVEEVVSTGLESPGGLAVDWVHDKLYWTDSGTSRIEVANLDGAHRKVLLWQNLEKPRAIALHPMEGTIYWTDWGNTPRIEASSMDGSGRRIIADTHLFWPNGLTIDYAGRRMYWVDAKHHVIERANLDGSHRKAVISQGLPHPFAITVFEDSLYWTDWHTKSINSANKFTGKNQEIIRNKLHFPMDIHTLHPQRQPAGKNRCGDNNGGCTHLCLPSGQNYTCACPTGFRKISSHACAQSLDKFLLFARRMDIRRISFDTEDLSDDVIPLADVRSAVALDWDSRDDHVYWTDVSTDTISRAKWDGTGQEVVVDTSLESPAGLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWENLDRPRDIVVEPMGGYMYWTDWGASPKIERAGMDASGRQVIISSNLTWPNGLAIDYGSQRLYWADAGMKTIEFAGLDGSKRKVLIGSQLPHPFGLTLYGERIYWTDWQTKSIQSADRLTGLDRETLQENLENLMDIHVFHRRRPPVSTPCAMENGGCSHLCLRSPNPSGFSCTCPTGINLLSDGKTCSPGMNSFLIFARRIDIRMVSLDIPYFADVVVPINITMKNTIAIGVDPQEGKVYWSDSTLHRISRANLDGSQHEDIITTGLQTTDGLAVDAIGRKVYWTDTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIVLYHEMGFMYWTDWGENAKLERSGMDGSDRAVLINNNLGWPNGLTVDKASSQLLWADAHTERIEAADLNGANRHTLVSPVQHPYGLTLLDSYIYWTDWQTRSIHRADKGTGSNVILVRSNLPGLMDMQAVDRAQPLGFNKCGSRNGGCSHLCLPRPSGFSCACPTGIQLKGDGKTCDPSPETYLLFSSRGSIRRISLDTSDHTDVHVPVPELNNVISLDYDSVDGKVYYTDVFLDVIRRADLNGSNMETVIGRGLKTTDGLAVDWVARNLYWTDTGRNTIEASRLDGSCRKVLINNSLDEPRAIAVFPRKGYLFWTDWGHIAKIERANLDGSERKVLINTDLGWPNGLTLDYDTRRIYWVDAHLDRIESADLNGKLRQVLVSHVSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGRNKETVLANVEGLMDIIVVSPQRQTGTNACGVNNGGCTHLCFARASDFVCACPDEPDSRPCSLVPGLVPPAPRATGMSEKSPVLPNTPPTTLYSSTTRTRTSLEEVEGRCSERDARLGLCARSNDAVPAAPGEGLHISYAIGGLLSILLILVVIAALMLYRHKKSKFTDPGMGNLTYSNPSYRTSTQEVKIEAIPKPAMYNQLCYKKEQLFHPSDSLSPFLF

Target ORF information:

RefSeq Version	XM_017017734.1
Organism	Homo sapiens(human)
Definition	Homo sapiens LDL receptor related protein 4 (LRP4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017017734.1

ORF Insert Sequence:

ATGAGGCGGC AGTGGGGCGC GCTGCTGCTT GGCGCCCTGC TCTGCGCACA CGGCCTGGCC 
AGCAGCCCCG AGTGTGCTTG TGGTCGGAGC CACTTCACAT GTGCAGTGAG TGCTCTTGGA 
GAGTGTACCT GCATCCCTGC CCAGTGGCAG TGTGATGGAG ACAATGACTG CGGGGACCAC 
AGCGATGAGG ATGGATGTAT ACTACCTACC TGTTCCCCTC TTGACTTTCA CTGTGACAAT 
GGCAAGTGCA TCCGCCGCTC CTGGGTGTGT GACGGGGACA ACGACTGTGA GGATGACTCG 
GATGAGCAGG ACTGTCCCCC CCGGGAGTGT GAGGAGGACG AGTTTCCCTG CCAGAATGGC 
TACTGCATCC GGAGTCTGTG GCACTGCGAT GGTGACAATG ACTGTGGCGA CAACAGCGAT 
GAGCAGTGTG ACATGCGCAA GTGCTCCGAC AAGGAGTTCC GCTGTAGTGA CGGAAGCTGC 
ATTGCTGAGC ATTGGTACTG CGACGGTGAC ACCGACTGCA AAGATGGCTC CGATGAGGAG 
AACTGTCCCT CAGCAGTGCC AGCGCCCCCC TGCAACCTGG AGGAGTTCCA GTGTGCCTAT 
GGACGCTGCA TCCTCGACAT CTACCACTGC GATGGCGACG ATGACTGTGG AGACTGGTCA 
GACGAGTCTG ACTGCTCCTC CCACCAGCCC TGCCGCTCTG GGGAGTTCAT GTGTGACAGT 
GGCCTGTGCA TCAATGCAGG CTGGCGCTGC GATGGTGACG CGGACTGTGA TGACCAGTCT 
GATGAGCGCA ACTGCACCAC CTCCATGTGT ACGGCAGAAC AGTTCCGCTG TCACTCAGGC 
CGCTGTGTCC GCCTGTCCTG GCGCTGTGAT GGGGAGGACG ACTGTGCAGA CAACAGCGAT 
GAAGAGAACT GTGAGAATAC AGGAAGCCCC CAATGTGCCT TGGACCAGTT CCTGTGTTGG 
AATGGGCGCT GCATTGGGCA GAGGAAGCTG TGCAACGGGG TCAACGACTG TGGTGACAAC 
AGCGACGAAA GCCCACAGCA GAATTGCCGG CCCCGGACGG GTGAGGAGAA CTGCAATGTT 
AACAACGGTG GCTGTGCCCA GAAGTGCCAG ATGGTGCGGG GGGCAGTGCA GTGTACCTGC 
CACACAGGCT ACCGGCTCAC AGAGGATGGG CACACGTGCC AAGATGTGAA TGAATGTGCC 
GAGGAGGGGT ATTGCAGCCA GGGCTGCACC AACAGCGAAG GGGCTTTCCA ATGCTGGTGT 
GAAACAGGCT ATGAACTACG GCCCGACCGG CGCAGCTGCA AGGCTCTGGG GCCAGAGCCT 
GTGCTGCTGT TCGCCAATCG CATCGACATC CGGCAGGTGC TGCCACACCG CTCTGAGTAC 
ACACTGCTGC TTAACAACCT GGAGAATGCC ATTGCCCTTG ATTTCCACCA CCGCCGCGAG 
CTTGTCTTCT GGTCAGATGT CACCCTGGAC CGGATCCTCC GTGCCAACCT CAACGGCAGC 
AACGTGGAGG AGGTTGTGTC TACTGGGCTG GAGAGCCCAG GGGGCCTGGC TGTGGATTGG 
GTCCATGACA AACTCTACTG GACCGACTCA GGCACCTCGA GGATTGAGGT GGCCAATCTG 
GATGGGGCCC ACCGGAAAGT GTTGCTGTGG CAGAACCTGG AGAAGCCCCG GGCCATTGCC 
TTGCATCCCA TGGAGGGTAC CATTTACTGG ACAGACTGGG GCAACACCCC CCGTATTGAG 
GCCTCCAGCA TGGATGGCTC TGGACGCCGC ATCATTGCCG ATACCCATCT CTTCTGGCCC 
AATGGCCTCA CCATCGACTA TGCCGGGCGC CGTATGTACT GGGTGGATGC TAAGCACCAT 
GTCATCGAGA GGGCCAATCT GGATGGGAGT CACCGTAAGG CTGTCATTAG CCAGGGCCTC 
CCGCATCCCT TCGCCATCAC AGTGTTTGAA GACAGCCTGT ACTGGACAGA CTGGCACACC 
AAGAGCATCA ATAGCGCTAA CAAATTTACG GGGAAGAACC AGGAAATCAT TCGCAACAAA 
CTCCACTTCC CTATGGACAT CCACACCTTG CACCCCCAGC GCCAACCTGC AGGGAAAAAC 
CGCTGTGGGG ACAACAACGG AGGCTGCACG CACCTGTGTC TGCCCAGTGG CCAGAACTAC 
ACCTGTGCCT GCCCCACTGG CTTCCGCAAG ATCAGCAGCC ACGCCTGTGC CCAGAGTCTT 
GACAAGTTCC TGCTTTTTGC CCGAAGGATG GACATCCGTC GAATCAGCTT TGACACAGAG 
GACCTGTCTG ATGATGTCAT CCCACTGGCT GACGTGCGCA GTGCTGTGGC CCTTGACTGG 
GACTCCCGGG ATGACCACGT GTACTGGACA GATGTCAGCA CTGATACCAT CAGCAGGGCC 
AAGTGGGATG GAACAGGACA GGAGGTGGTA GTGGATACCA GTTTGGAGAG CCCAGCTGGC 
CTGGCCATTG ATTGGGTCAC CAACAAACTG TACTGGACAG ATGCAGGTAC AGACCGGATT 
GAAGTAGCCA ACACAGATGG CAGCATGAGA ACAGTACTCA TCTGGGAGAA CCTTGATCGT 
CCTCGGGACA TCGTGGTGGA ACCCATGGGC GGGTACATGT ATTGGACTGA CTGGGGTGCG 
AGCCCCAAGA TTGAACGAGC TGGCATGGAT GCCTCAGGCC GCCAAGTCAT TATCTCTTCT 
AATCTGACCT GGCCTAATGG GTTAGCTATT GATTATGGGT CCCAGCGTCT ATACTGGGCT 
GACGCCGGCA TGAAGACAAT TGAATTTGCT GGACTGGATG GCAGTAAGAG GAAGGTGCTG 
ATTGGAAGCC AGCTCCCCCA CCCATTTGGG CTGACCCTCT ATGGAGAGCG CATCTATTGG 
ACTGACTGGC AGACCAAGAG CATACAGAGC GCTGACCGGC TGACAGGGCT GGACCGGGAG 
ACTCTGCAGG AGAACCTGGA AAACCTAATG GACATCCATG TCTTCCACCG CCGCCGGCCC 
CCAGTGTCTA CACCATGTGC TATGGAGAAT GGCGGCTGTA GCCACCTGTG TCTTAGGTCC 
CCAAATCCAA GCGGATTCAG CTGTACCTGC CCCACAGGCA TCAACCTGCT GTCTGATGGC 
AAGACCTGCT CACCAGGCAT GAACAGTTTC CTCATCTTCG CCAGGAGGAT AGACATTCGC 
ATGGTCTCCC TGGACATCCC TTATTTTGCT GATGTGGTGG TACCAATCAA CATTACCATG 
AAGAACACCA TTGCCATTGG AGTAGACCCC CAGGAAGGAA AGGTGTACTG GTCTGACAGC 
ACACTGCACA GGATCAGTCG TGCCAATCTG GATGGCTCAC AGCATGAGGA CATCATCACC 
ACAGGGCTAC AGACCACAGA TGGGCTCGCG GTTGATGCCA TTGGCCGGAA AGTATACTGG 
ACAGACACGG GAACAAACCG GATTGAAGTG GGCAACCTGG ACGGGTCCAT GCGGAAAGTG 
TTGGTGTGGC AGAACCTTGA CAGTCCCCGG GCCATCGTAC TGTACCATGA GATGGGGTTT 
ATGTACTGGA CAGACTGGGG GGAGAATGCC AAGTTAGAGC GGTCCGGAAT GGATGGCTCA 
GACCGCGCGG TGCTCATCAA CAACAACCTA GGATGGCCCA ATGGACTGAC TGTGGACAAG 
GCCAGCTCCC AACTGCTATG GGCCGATGCC CACACCGAGC GAATTGAGGC TGCTGACCTG 
AATGGTGCCA ATCGGCATAC ATTGGTGTCA CCGGTGCAGC ACCCATATGG CCTCACCCTG 
CTCGACTCCT ATATCTACTG GACTGACTGG CAGACTCGGA GCATCCACCG TGCTGACAAG 
GGTACTGGCA GCAATGTCAT CCTCGTGAGG TCCAACCTGC CAGGCCTCAT GGACATGCAG 
GCTGTGGACC GGGCACAGCC ACTAGGTTTT AACAAGTGCG GCTCGAGAAA TGGCGGCTGC 
TCCCACCTCT GCTTGCCTCG GCCTTCTGGC TTCTCCTGTG CCTGCCCCAC TGGCATCCAG 
CTGAAGGGAG ATGGGAAGAC CTGTGATCCC TCTCCTGAGA CCTACCTGCT CTTCTCCAGC 
CGTGGCTCCA TCCGGCGTAT CTCACTGGAC ACCAGTGACC ACACCGATGT GCATGTCCCT 
GTTCCTGAGC TCAACAATGT CATCTCCCTG GACTATGACA GCGTGGATGG AAAGGTCTAT 
TACACAGATG TGTTCCTGGA TGTTATCAGG CGAGCAGACC TGAACGGCAG CAACATGGAG 
ACAGTGATCG GGCGAGGGCT GAAGACCACT GACGGGCTGG CAGTGGACTG GGTGGCCAGG 
AACCTGTACT GGACAGACAC AGGTCGAAAT ACCATTGAGG CGTCCAGGCT GGATGGTTCC 
TGCCGCAAAG TACTGATCAA CAATAGCCTG GATGAGCCCC GGGCCATTGC TGTTTTCCCC 
AGGAAGGGGT ACCTCTTCTG GACAGACTGG GGCCACATTG CCAAGATCGA ACGGGCAAAC 
TTGGATGGTT CTGAGCGGAA GGTCCTCATC AACACAGACC TGGGTTGGCC CAATGGCCTT 
ACCCTGGACT ATGATACCCG CAGGATCTAC TGGGTGGATG CGCATCTGGA CCGGATCGAG 
AGTGCTGACC TCAATGGGAA ACTGCGGCAG GTCTTGGTCA GCCATGTGTC CCACCCCTTT 
GCCCTCACAC AGCAAGACAG GTGGATCTAC TGGACAGACT GGCAGACCAA GTCAATCCAG 
CGTGTTGACA AATACTCAGG CCGGAACAAG GAGACAGTGC TGGCAAATGT GGAAGGACTC 
ATGGATATCA TCGTGGTTTC CCCTCAGCGG CAGACAGGGA CCAATGCCTG TGGTGTGAAC 
AATGGTGGCT GCACCCACCT CTGCTTTGCC AGAGCCTCGG ACTTCGTATG TGCCTGTCCT 
GACGAACCTG ATAGCCGGCC CTGCTCCCTT GTGCCTGGCC TGGTACCACC AGCTCCTAGG 
GCTACTGGCA TGAGTGAAAA GAGCCCAGTG CTACCCAACA CACCACCTAC CACCTTGTAT 
TCTTCAACCA CCCGGACCCG CACGTCTCTG GAGGAGGTGG AAGGAAGATG CTCTGAAAGG 
GATGCCAGGC TGGGCCTCTG TGCACGTTCC AATGACGCTG TTCCTGCTGC TCCAGGGGAA 
GGACTTCATA TCAGCTACGC CATTGGTGGA CTCCTCAGTA TTCTGCTGAT TTTGGTGGTG 
ATTGCAGCTT TGATGCTGTA CAGACACAAA AAATCCAAGT TCACTGATCC TGGAATGGGG 
AACCTCACCT ACAGCAACCC CTCCTACCGA ACATCCACAC AGGAAGTGAA GATTGAAGCA 
ATCCCCAAAC CAGCCATGTA CAACCAGCTG TGCTATAAGA AAGAGCAGCT CTTTCACCCC 
TCTGATAGTC TTTCACCTTT TCTCTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Novel splice mutation in LRP4 causes severe type of Cenani-Lenz syndactyly syndrome with oro-facial and skeletal symptoms.
European journal of medical genetics60(8)421-425(2017 Aug)
Afzal M,Zaman Q,Kornak U,Mundlos S,Malik S,Fl?ttmann R

Exome sequencing of two Italian pedigrees with non-isolated Chiari malformation type I reveals candidate genes for cranio-facial development.
European journal of human genetics : EJHG25(8)952-959(2017 Aug)
Merello E,Tattini L,Magi A,Accogli A,Piatelli G,Pavanello M,Tortora D,Cama A,Kibar Z,Capra V,De Marco P

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LRP4 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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