FADS3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	FADS3
Entrez Gene ID	3995
Full Name	fatty acid desaturase 3
Synonyms	CYB5RP,LLCDL3
General protein information	Preferred Names fatty acid desaturase 3 Names fatty acid desaturase 3 cytochrome b5-related protein delta-9 fatty acid desaturase delta-9-desaturase linoleoyl-CoA desaturase (delta-9-desaturase)-like 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11q12.2
Summary	The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. [provided by RefSeq, Jul 2008].
Disorder MIM:	606150

mRNA and Protein(s)

mRNA	Protein	Name
XM_017017724.1	XP_016873213.1	fatty acid desaturase 3 isoform X2
NM_021727.5	NP_068373.1	fatty acid desaturase 3
XM_011545023.2	XP_011543325.1	fatty acid desaturase 3 isoform X3
NM_021727.4	NP_068373.1	fatty acid desaturase 3
XM_017017723.1	XP_016873212.1	fatty acid desaturase 3 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	FADS3	NP_068373.1
Pan troglodytes (chimpanzee)	FADS3	XP_508484.2
Canis lupus familiaris (dog)	FADS3	XP_533270.4
Mus musculus (house mouse)	Fads3	NP_068690.3
Bos taurus (cattle)	FADS3	NP_001077160.1
	FADS3	XP_002799573.1
Rattus norvegicus (Norway rat)	Fads3	NP_775160.1

Gene Ontology
Bibliography

Related articles in PubMed

Association of the FADS gene cluster with coronary artery disease and plasma lipid concentrations in the northern Chinese Han population.
Wu Y, Zeng L, Chen X, Xu Y, Ye L, Qin L, Chen L, Xie L
Prostaglandins, leukotrienes, and essential fatty acids11711-16(2017 Feb)

Association of polyunsaturated fatty acids in breast milk with fatty acid desaturase gene polymorphisms among Chinese lactating mothers.
Ding Z, Liu GL, Li X, Chen XY, Wu YX, Cui CC, Zhang X, Yang G, Xie L
Prostaglandins, leukotrienes, and essential fatty acids10966-71(2016 06)

Genome-wide association study identifies three susceptibility loci for laryngeal squamous cell carcinoma in the Chinese population.
Wei Q, Yu D, Liu M, Wang M, Zhao M, Liu M, Jia W, Ma H, Fang J, Xu W, Chen K, Xu Z, Wang J, Tian L, Yuan H, Chang J, Hu Z, Wei L, Huang Y, Han Y, Liu J, Han D, Shen H, Yang S, Zheng H, Ji Q, Li D, Tan W, Wu C, Lin D
Nature genetics46(10)1110-4(2014 Oct)

Genetic variants in desaturase gene, erythrocyte fatty acids, and risk for type 2 diabetes in Chinese Hans.
Huang T, Sun J, Chen Y, Xie H, Xu D, Huang J, Li D
Nutrition (Burbank, Los Angeles County, Calif.)30(7-8)897-902(2014 Jul-Aug)

Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium.
Guan W, Steffen BT, Lemaitre RN, Wu JHY, Tanaka T, Manichaikul A, Foy M, Rich SS, Wang L, Nettleton JA, Tang W, Gu X, Bandinelli S, King IB, McKnight B, Psaty BM, Siscovick D, Djousse L, Chen YI, Ferrucci L, Fornage M, Mozafarrian D, Tsai MY, Steffen LM
Circulation. Cardiovascular genetics7(3)321-331(2014 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data demonstrated that the rs1000778-G allele in the FADS3 gene is related to increased risk for coronary artery disease in the northern Chinese Han population.
Title: Association of the FADS gene cluster with coronary artery disease and plasma lipid concentrations in the northern Chinese Han population.

pairwise comparison showed that individuals major homozygous for the SNP rs1000778 in the FADS3 gene had lower concentrations of a-linolenic acid and linoleic acid in their breast milk
Title: Association of polyunsaturated fatty acids in breast milk with fatty acid desaturase gene polymorphisms among Chinese lactating mothers.

Minor allele homozygotes and heterozygotes of rs174455 in FADS3 gene had lower levels of 22:5 omega-3, 20:4 omega-6, and Delta5desaturase activity in patients with type 2 diabetes mellitus.
Title: Genetic variants in desaturase gene, erythrocyte fatty acids, and risk for type 2 diabetes in Chinese Hans.

genetic association study in maternal/child dyads in England: Data suggest that SNPs in FADS3 (and in FADS1/FADS2) influence fetal fatty acid metabolism; both maternal and child FADS genotypes/haplotypes influence cord plasma long-chain fatty acids.
Title: Umbilical cord PUFA are determined by maternal and child fatty acid desaturase (FADS) genetic variants in the Avon Longitudinal Study of Parents and Children (ALSPAC).

Data suggest that FADS3 alternative transcripts/splicing are up-regulated in liver by dietary docosahexaenoic/arachidonic acids by peroxisome proliferator-activated receptor gamma (PPARg)-dependent mechanism unrelated to other desaturases (FADS1/2).
Title: Dietary long-chain polyunsaturated fatty acids upregulate expression of FADS3 transcripts.

The following FADS3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FADS3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu27562	NM_021727.5 Latest version!	Homo sapiens fatty acid desaturase 3 (FADS3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu92226	XM_017017724.1 Latest version!	Homo sapiens fatty acid desaturase 3 (FADS3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu92225	XM_017017723.1 Latest version!	Homo sapiens fatty acid desaturase 3 (FADS3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OHu58726	XM_011545023.2 Latest version!	Homo sapiens fatty acid desaturase 3 (FADS3), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
View Old Accession Versions >>
OHu27562	NM_021727.4	Homo sapiens fatty acid desaturase 3 (FADS3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

FADS3 ( NM_021727.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_068373.1 Homo sapiens fatty acid desaturase 3 (FADS3), mRNA.

Price & Availability↑

CloneID	OHu27562
Clone ID Related Accession (Same CDS sequence)	NM_021727.5 , NM_021727.4
Accession Version	NM_021727.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1338bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-01
Organism	Homo sapiens(human)
Product	fatty acid desaturase 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP006260.2. On Nov 23, 2018 this sequence version replaced NM_021727.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC004901.2, AF084560.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000278829.7/ ENSP00000278829.2 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGCGGCG TCGGGGAGCC GGGACCGCGG GAGGGACCCG CGCAGCCGGG GGCGCCGCTG 
CCCACCTTCT GCTGGGAGCA GATCCGCGCG CACGACCAGC CCGGCGACAA GTGGCTGGTC 
ATCGAGCGCC GCGTCTACGA CATCAGCCGC TGGGCACAGC GGCACCCAGG GGGCAGCCGC 
CTCATCGGCC ACCACGGCGC TGAGGACGCC ACGGATGCCT TCCGTGCCTT CCATCAAGAT 
CTCAATTTTG TGCGCAAGTT CCTACAGCCC CTGTTGATTG GAGAGCTGGC TCCGGAAGAA 
CCCAGCCAGG ATGGACCCCT GAATGCGCAG CTGGTCGAGG ACTTCCGAGC CCTGCACCAG 
GCAGCCGAGG ACATGAAGCT GTTTGATGCC AGTCCCACCT TCTTTGCTTT CCTACTGGGC 
CACATCCTGG CCATGGAGGT GCTGGCCTGG CTCCTTATCT ACCTCCTGGG TCCTGGCTGG 
GTGCCCAGTG CCCTGGCCGC CTTCATCCTG GCCATCTCTC AGGCTCAGTC CTGGTGTCTG 
CAGCATGACC TGGGCCATGC CTCCATCTTC AAGAAGTCCT GGTGGAACCA CGTGGCCCAG 
AAGTTCGTGA TGGGGCAGCT AAAGGGCTTC TCCGCCCACT GGTGGAACTT CCGCCACTTC 
CAGCACCACG CCAAGCCCAA CATCTTCCAC AAAGACCCAG ACGTGACGGT GGCGCCCGTC 
TTCCTCCTGG GGGAGTCATC CGTCGAGTAT GGCAAGAAGA AACGCAGATA CCTACCCTAC 
AACCAGCAGC ACCTGTACTT CTTCCTGATC GGCCCGCCGC TGCTCACCCT GGTGAACTTT 
GAAGTGGAAA ATCTGGCGTA CATGCTGGTG TGCATGCAGT GGGCGGATTT GCTCTGGGCC 
GCCAGCTTCT ATGCCCGCTT CTTCTTATCC TACCTCCCCT TCTACGGCGT CCCTGGGGTG 
CTGCTCTTCT TTGTTGCTGT CAGGGTCCTG GAAAGCCACT GGTTCGTGTG GATCACACAG 
ATGAACCACA TCCCCAAGGA GATCGGCCAC GAGAAGCACC GGGACTGGGT CAGCTCTCAG 
CTGGCAGCCA CCTGCAACGT GGAGCCCTCA CTTTTCACCA ACTGGTTCAG CGGGCACCTC 
AACTTCCAGA TCGAGCACCA CCTCTTCCCC AGGATGCCGA GACACAACTA CAGCCGGGTG 
GCCCCGCTGG TCAAGTCGCT GTGTGCCAAG CACGGCCTCA GCTACGAAGT GAAGCCCTTC 
CTCACCGCGC TGGTGGACAT CGTCAGGTCC CTGAAGAAGT CTGGTGACAT CTGGCTGGAC 
GCCTACCTCC ATCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_068373.1
CDS	165..1502
Translation	MGGVGEPGPREGPAQPGAPLPTFCWEQIRAHDQPGDKWLVIERRVYDISRWAQRHPGGSRLIGHHGAEDATDAFRAFHQDLNFVRKFLQPLLIGELAPEEPSQDGPLNAQLVEDFRALHQAAEDMKLFDASPTFFAFLLGHILAMEVLAWLLIYLLGPGWVPSALAAFILAISQAQSWCLQHDLGHASIFKKSWWNHVAQKFVMGQLKGFSAHWWNFRHFQHHAKPNIFHKDPDVTVAPVFLLGESSVEYGKKKRRYLPYNQQHLYFFLIGPPLLTLVNFEVENLAYMLVCMQWADLLWAASFYARFFLSYLPFYGVPGVLLFFVAVRVLESHWFVWITQMNHIPKEIGHEKHRDWVSSQLAATCNVEPSLFTNWFSGHLNFQIEHHLFPRMPRHNYSRVAPLVKSLCAKHGLSYEVKPFLTALVDIVRSLKKSGDIWLDAYLHQ

Target ORF information:

RefSeq Version	NM_021727.5
Organism	Homo sapiens(human)
Definition	Homo sapiens fatty acid desaturase 3 (FADS3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021727.5

ORF Insert Sequence:

ATGGGCGGCG TCGGGGAGCC GGGACCGCGG GAGGGACCCG CGCAGCCGGG GGCGCCGCTG 
CCCACCTTCT GCTGGGAGCA GATCCGCGCG CACGACCAGC CCGGCGACAA GTGGCTGGTC 
ATCGAGCGCC GCGTCTACGA CATCAGCCGC TGGGCACAGC GGCACCCAGG GGGCAGCCGC 
CTCATCGGCC ACCACGGCGC TGAGGACGCC ACGGATGCCT TCCGTGCCTT CCATCAAGAT 
CTCAATTTTG TGCGCAAGTT CCTACAGCCC CTGTTGATTG GAGAGCTGGC TCCGGAAGAA 
CCCAGCCAGG ATGGACCCCT GAATGCGCAG CTGGTCGAGG ACTTCCGAGC CCTGCACCAG 
GCAGCCGAGG ACATGAAGCT GTTTGATGCC AGTCCCACCT TCTTTGCTTT CCTACTGGGC 
CACATCCTGG CCATGGAGGT GCTGGCCTGG CTCCTTATCT ACCTCCTGGG TCCTGGCTGG 
GTGCCCAGTG CCCTGGCCGC CTTCATCCTG GCCATCTCTC AGGCTCAGTC CTGGTGTCTG 
CAGCATGACC TGGGCCATGC CTCCATCTTC AAGAAGTCCT GGTGGAACCA CGTGGCCCAG 
AAGTTCGTGA TGGGGCAGCT AAAGGGCTTC TCCGCCCACT GGTGGAACTT CCGCCACTTC 
CAGCACCACG CCAAGCCCAA CATCTTCCAC AAAGACCCAG ACGTGACGGT GGCGCCCGTC 
TTCCTCCTGG GGGAGTCATC CGTCGAGTAT GGCAAGAAGA AACGCAGATA CCTACCCTAC 
AACCAGCAGC ACCTGTACTT CTTCCTGATC GGCCCGCCGC TGCTCACCCT GGTGAACTTT 
GAAGTGGAAA ATCTGGCGTA CATGCTGGTG TGCATGCAGT GGGCGGATTT GCTCTGGGCC 
GCCAGCTTCT ATGCCCGCTT CTTCTTATCC TACCTCCCCT TCTACGGCGT CCCTGGGGTG 
CTGCTCTTCT TTGTTGCTGT CAGGGTCCTG GAAAGCCACT GGTTCGTGTG GATCACACAG 
ATGAACCACA TCCCCAAGGA GATCGGCCAC GAGAAGCACC GGGACTGGGT CAGCTCTCAG 
CTGGCAGCCA CCTGCAACGT GGAGCCCTCA CTTTTCACCA ACTGGTTCAG CGGGCACCTC 
AACTTCCAGA TCGAGCACCA CCTCTTCCCC AGGATGCCGA GACACAACTA CAGCCGGGTG 
GCCCCGCTGG TCAAGTCGCT GTGTGCCAAG CACGGCCTCA GCTACGAAGT GAAGCCCTTC 
CTCACCGCGC TGGTGGACAT CGTCAGGTCC CTGAAGAAGT CTGGTGACAT CTGGCTGGAC 
GCCTACCTCC ATCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FADS3 ( NM_021727.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_068373.1 Homo sapiens fatty acid desaturase 3 (FADS3), mRNA.

Price & Availability↑

CloneID	OHu27562
Clone ID Related Accession (Same CDS sequence)	NM_021727.5 , NM_021727.4
Accession Version	NM_021727.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1338bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-17
Organism	Homo sapiens(human)
Product	fatty acid desaturase 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA662142.1, BC004901.2 and AW080967.1. On Sep 11, 2013 this sequence version replaced NM_021727.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC004901.2, AF084560.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGCGGCG TCGGGGAGCC GGGACCGCGG GAGGGACCCG CGCAGCCGGG GGCGCCGCTG 
CCCACCTTCT GCTGGGAGCA GATCCGCGCG CACGACCAGC CCGGCGACAA GTGGCTGGTC 
ATCGAGCGCC GCGTCTACGA CATCAGCCGC TGGGCACAGC GGCACCCAGG GGGCAGCCGC 
CTCATCGGCC ACCACGGCGC TGAGGACGCC ACGGATGCCT TCCGTGCCTT CCATCAAGAT 
CTCAATTTTG TGCGCAAGTT CCTACAGCCC CTGTTGATTG GAGAGCTGGC TCCGGAAGAA 
CCCAGCCAGG ATGGACCCCT GAATGCGCAG CTGGTCGAGG ACTTCCGAGC CCTGCACCAG 
GCAGCCGAGG ACATGAAGCT GTTTGATGCC AGTCCCACCT TCTTTGCTTT CCTACTGGGC 
CACATCCTGG CCATGGAGGT GCTGGCCTGG CTCCTTATCT ACCTCCTGGG TCCTGGCTGG 
GTGCCCAGTG CCCTGGCCGC CTTCATCCTG GCCATCTCTC AGGCTCAGTC CTGGTGTCTG 
CAGCATGACC TGGGCCATGC CTCCATCTTC AAGAAGTCCT GGTGGAACCA CGTGGCCCAG 
AAGTTCGTGA TGGGGCAGCT AAAGGGCTTC TCCGCCCACT GGTGGAACTT CCGCCACTTC 
CAGCACCACG CCAAGCCCAA CATCTTCCAC AAAGACCCAG ACGTGACGGT GGCGCCCGTC 
TTCCTCCTGG GGGAGTCATC CGTCGAGTAT GGCAAGAAGA AACGCAGATA CCTACCCTAC 
AACCAGCAGC ACCTGTACTT CTTCCTGATC GGCCCGCCGC TGCTCACCCT GGTGAACTTT 
GAAGTGGAAA ATCTGGCGTA CATGCTGGTG TGCATGCAGT GGGCGGATTT GCTCTGGGCC 
GCCAGCTTCT ATGCCCGCTT CTTCTTATCC TACCTCCCCT TCTACGGCGT CCCTGGGGTG 
CTGCTCTTCT TTGTTGCTGT CAGGGTCCTG GAAAGCCACT GGTTCGTGTG GATCACACAG 
ATGAACCACA TCCCCAAGGA GATCGGCCAC GAGAAGCACC GGGACTGGGT CAGCTCTCAG 
CTGGCAGCCA CCTGCAACGT GGAGCCCTCA CTTTTCACCA ACTGGTTCAG CGGGCACCTC 
AACTTCCAGA TCGAGCACCA CCTCTTCCCC AGGATGCCGA GACACAACTA CAGCCGGGTG 
GCCCCGCTGG TCAAGTCGCT GTGTGCCAAG CACGGCCTCA GCTACGAAGT GAAGCCCTTC 
CTCACCGCGC TGGTGGACAT CGTCAGGTCC CTGAAGAAGT CTGGTGACAT CTGGCTGGAC 
GCCTACCTCC ATCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_068373.1
CDS	165..1502
Translation	MGGVGEPGPREGPAQPGAPLPTFCWEQIRAHDQPGDKWLVIERRVYDISRWAQRHPGGSRLIGHHGAEDATDAFRAFHQDLNFVRKFLQPLLIGELAPEEPSQDGPLNAQLVEDFRALHQAAEDMKLFDASPTFFAFLLGHILAMEVLAWLLIYLLGPGWVPSALAAFILAISQAQSWCLQHDLGHASIFKKSWWNHVAQKFVMGQLKGFSAHWWNFRHFQHHAKPNIFHKDPDVTVAPVFLLGESSVEYGKKKRRYLPYNQQHLYFFLIGPPLLTLVNFEVENLAYMLVCMQWADLLWAASFYARFFLSYLPFYGVPGVLLFFVAVRVLESHWFVWITQMNHIPKEIGHEKHRDWVSSQLAATCNVEPSLFTNWFSGHLNFQIEHHLFPRMPRHNYSRVAPLVKSLCAKHGLSYEVKPFLTALVDIVRSLKKSGDIWLDAYLHQ

Target ORF information:

RefSeq Version	NM_021727.4
Organism	Homo sapiens(human)
Definition	Homo sapiens fatty acid desaturase 3 (FADS3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021727.4

ORF Insert Sequence:

ATGGGCGGCG TCGGGGAGCC GGGACCGCGG GAGGGACCCG CGCAGCCGGG GGCGCCGCTG 
CCCACCTTCT GCTGGGAGCA GATCCGCGCG CACGACCAGC CCGGCGACAA GTGGCTGGTC 
ATCGAGCGCC GCGTCTACGA CATCAGCCGC TGGGCACAGC GGCACCCAGG GGGCAGCCGC 
CTCATCGGCC ACCACGGCGC TGAGGACGCC ACGGATGCCT TCCGTGCCTT CCATCAAGAT 
CTCAATTTTG TGCGCAAGTT CCTACAGCCC CTGTTGATTG GAGAGCTGGC TCCGGAAGAA 
CCCAGCCAGG ATGGACCCCT GAATGCGCAG CTGGTCGAGG ACTTCCGAGC CCTGCACCAG 
GCAGCCGAGG ACATGAAGCT GTTTGATGCC AGTCCCACCT TCTTTGCTTT CCTACTGGGC 
CACATCCTGG CCATGGAGGT GCTGGCCTGG CTCCTTATCT ACCTCCTGGG TCCTGGCTGG 
GTGCCCAGTG CCCTGGCCGC CTTCATCCTG GCCATCTCTC AGGCTCAGTC CTGGTGTCTG 
CAGCATGACC TGGGCCATGC CTCCATCTTC AAGAAGTCCT GGTGGAACCA CGTGGCCCAG 
AAGTTCGTGA TGGGGCAGCT AAAGGGCTTC TCCGCCCACT GGTGGAACTT CCGCCACTTC 
CAGCACCACG CCAAGCCCAA CATCTTCCAC AAAGACCCAG ACGTGACGGT GGCGCCCGTC 
TTCCTCCTGG GGGAGTCATC CGTCGAGTAT GGCAAGAAGA AACGCAGATA CCTACCCTAC 
AACCAGCAGC ACCTGTACTT CTTCCTGATC GGCCCGCCGC TGCTCACCCT GGTGAACTTT 
GAAGTGGAAA ATCTGGCGTA CATGCTGGTG TGCATGCAGT GGGCGGATTT GCTCTGGGCC 
GCCAGCTTCT ATGCCCGCTT CTTCTTATCC TACCTCCCCT TCTACGGCGT CCCTGGGGTG 
CTGCTCTTCT TTGTTGCTGT CAGGGTCCTG GAAAGCCACT GGTTCGTGTG GATCACACAG 
ATGAACCACA TCCCCAAGGA GATCGGCCAC GAGAAGCACC GGGACTGGGT CAGCTCTCAG 
CTGGCAGCCA CCTGCAACGT GGAGCCCTCA CTTTTCACCA ACTGGTTCAG CGGGCACCTC 
AACTTCCAGA TCGAGCACCA CCTCTTCCCC AGGATGCCGA GACACAACTA CAGCCGGGTG 
GCCCCGCTGG TCAAGTCGCT GTGTGCCAAG CACGGCCTCA GCTACGAAGT GAAGCCCTTC 
CTCACCGCGC TGGTGGACAT CGTCAGGTCC CTGAAGAAGT CTGGTGACAT CTGGCTGGAC 
GCCTACCTCC ATCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FADS3 ( XM_017017724.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016873213.1 Homo sapiens fatty acid desaturase 3 (FADS3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu92226
Clone ID Related Accession (Same CDS sequence)	XM_017017724.1
Accession Version	XM_017017724.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1476bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	fatty acid desaturase 3 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATGGCA GCGCCCGCCT CCACGCGCCA GTGCCCTCCT GCTCCCCTAC CTCCCCCTTG 
GCCACCCCTG GGCATCCCCA GCCCTGCAGC GCCGAGGGCG GAGGGGAGGC CACCCGCCCC 
CAGCAGAGGG CTCCGAGAGA GCTGCAGCGG CGGTGGGGGC CCCGCAGAGA TTGGGGCCCA 
TGGTTTGAAG GCTGTTCACA GGCACCCCGA GACAGCGTCC CCCCTCTGGG CGCACTGGAT 
TTGACGTTGC AGGACGCGCG GCTGGAAGCC CCCCAGGCCC CGCTGCTCAC AGACCGGGAC 
TCCGCCTCCG GTTCCCGAGG GCGTGGCGAG GCGCTGCGGG ACGCCCAACA GGATGCCTTC 
CGTGCCTTCC ATCAAGATCT CAATTTTGTG CGCAAGTTCC TACAGCCCCT GTTGATTGGA 
GAGCTGGCTC CGGAAGAACC CAGCCAGGAT GGACCCCTGA ATGCGCAGCT GGTCGAGGAC 
TTCCGAGCCC TGCACCAGGC AGCCGAGGAC ATGAAGCTGT TTGATGCCAG TCCCACCTTC 
TTTGCTTTCC TACTGGGCCA CATCCTGGCC ATGGAGGTGC TGGCCTGGCT CCTTATCTAC 
CTCCTGGGTC CTGGCTGGGT GCCCAGTGCC CTGGCCGCCT TCATCCTGGC CATCTCTCAG 
GCTCAGTCCT GGTGTCTGCA GCATGACCTG GGCCATGCCT CCATCTTCAA GAAGTCCTGG 
TGGAACCACG TGGCCCAGAA GTTCGTGATG GGGCAGCTAA AGGGCTTCTC CGCCCACTGG 
TGGAACTTCC GCCACTTCCA GCACCACGCC AAGCCCAACA TCTTCCACAA AGACCCAGAC 
GTGACGGTGG CGCCCGTCTT CCTCCTGGGG GAGTCATCCG TCGAGTATGG CAAGAAGAAA 
CGCAGATACC TACCCTACAA CCAGCAGCAC CTGTACTTCT TCCTGATCGG CCCGCCGCTG 
CTCACCCTGG TGAACTTTGA AGTGGAAAAT CTGGCGTACA TGCTGGTGTG CATGCAGTGG 
GCGGATTTGC TCTGGGCCGC CAGCTTCTAT GCCCGCTTCT TCTTATCCTA CCTCCCCTTC 
TACGGCGTCC CTGGGGTGCT GCTCTTCTTT GTTGCTGTCA GGGTCCTGGA AAGCCACTGG 
TTCGTGTGGA TCACACAGAT GAACCACATC CCCAAGGAGA TCGGCCACGA GAAGCACCGG 
GACTGGGTCA GCTCTCAGCT GGCAGCCACC TGCAACGTGG AGCCCTCACT TTTCACCAAC 
TGGTTCAGCG GGCACCTCAA CTTCCAGATC GAGCACCACC TCTTCCCCAG GATGCCGAGA 
CACAACTACA GCCGGGTGGC CCCGCTGGTC AAGTCGCTGT GTGCCAAGCA CGGCCTCAGC 
TACGAAGTGA AGCCCTTCCT CACCGCGCTG GTGGACATCG TCAGGTCCCT GAAGAAGTCT 
GGTGACATCT GGCTGGACGC CTACCTCCAT CAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016873213.1
CDS	16..1491
Translation	MDGSARLHAPVPSCSPTSPLATPGHPQPCSAEGGGEATRPQQRAPRELQRRWGPRRDWGPWFEGCSQAPRDSVPPLGALDLTLQDARLEAPQAPLLTDRDSASGSRGRGEALRDAQQDAFRAFHQDLNFVRKFLQPLLIGELAPEEPSQDGPLNAQLVEDFRALHQAAEDMKLFDASPTFFAFLLGHILAMEVLAWLLIYLLGPGWVPSALAAFILAISQAQSWCLQHDLGHASIFKKSWWNHVAQKFVMGQLKGFSAHWWNFRHFQHHAKPNIFHKDPDVTVAPVFLLGESSVEYGKKKRRYLPYNQQHLYFFLIGPPLLTLVNFEVENLAYMLVCMQWADLLWAASFYARFFLSYLPFYGVPGVLLFFVAVRVLESHWFVWITQMNHIPKEIGHEKHRDWVSSQLAATCNVEPSLFTNWFSGHLNFQIEHHLFPRMPRHNYSRVAPLVKSLCAKHGLSYEVKPFLTALVDIVRSLKKSGDIWLDAYLHQ

Target ORF information:

RefSeq Version	XM_017017724.1
Organism	Homo sapiens(human)
Definition	Homo sapiens fatty acid desaturase 3 (FADS3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017017724.1

ORF Insert Sequence:

ATGGATGGCA GCGCCCGCCT CCACGCGCCA GTGCCCTCCT GCTCCCCTAC CTCCCCCTTG 
GCCACCCCTG GGCATCCCCA GCCCTGCAGC GCCGAGGGCG GAGGGGAGGC CACCCGCCCC 
CAGCAGAGGG CTCCGAGAGA GCTGCAGCGG CGGTGGGGGC CCCGCAGAGA TTGGGGCCCA 
TGGTTTGAAG GCTGTTCACA GGCACCCCGA GACAGCGTCC CCCCTCTGGG CGCACTGGAT 
TTGACGTTGC AGGACGCGCG GCTGGAAGCC CCCCAGGCCC CGCTGCTCAC AGACCGGGAC 
TCCGCCTCCG GTTCCCGAGG GCGTGGCGAG GCGCTGCGGG ACGCCCAACA GGATGCCTTC 
CGTGCCTTCC ATCAAGATCT CAATTTTGTG CGCAAGTTCC TACAGCCCCT GTTGATTGGA 
GAGCTGGCTC CGGAAGAACC CAGCCAGGAT GGACCCCTGA ATGCGCAGCT GGTCGAGGAC 
TTCCGAGCCC TGCACCAGGC AGCCGAGGAC ATGAAGCTGT TTGATGCCAG TCCCACCTTC 
TTTGCTTTCC TACTGGGCCA CATCCTGGCC ATGGAGGTGC TGGCCTGGCT CCTTATCTAC 
CTCCTGGGTC CTGGCTGGGT GCCCAGTGCC CTGGCCGCCT TCATCCTGGC CATCTCTCAG 
GCTCAGTCCT GGTGTCTGCA GCATGACCTG GGCCATGCCT CCATCTTCAA GAAGTCCTGG 
TGGAACCACG TGGCCCAGAA GTTCGTGATG GGGCAGCTAA AGGGCTTCTC CGCCCACTGG 
TGGAACTTCC GCCACTTCCA GCACCACGCC AAGCCCAACA TCTTCCACAA AGACCCAGAC 
GTGACGGTGG CGCCCGTCTT CCTCCTGGGG GAGTCATCCG TCGAGTATGG CAAGAAGAAA 
CGCAGATACC TACCCTACAA CCAGCAGCAC CTGTACTTCT TCCTGATCGG CCCGCCGCTG 
CTCACCCTGG TGAACTTTGA AGTGGAAAAT CTGGCGTACA TGCTGGTGTG CATGCAGTGG 
GCGGATTTGC TCTGGGCCGC CAGCTTCTAT GCCCGCTTCT TCTTATCCTA CCTCCCCTTC 
TACGGCGTCC CTGGGGTGCT GCTCTTCTTT GTTGCTGTCA GGGTCCTGGA AAGCCACTGG 
TTCGTGTGGA TCACACAGAT GAACCACATC CCCAAGGAGA TCGGCCACGA GAAGCACCGG 
GACTGGGTCA GCTCTCAGCT GGCAGCCACC TGCAACGTGG AGCCCTCACT TTTCACCAAC 
TGGTTCAGCG GGCACCTCAA CTTCCAGATC GAGCACCACC TCTTCCCCAG GATGCCGAGA 
CACAACTACA GCCGGGTGGC CCCGCTGGTC AAGTCGCTGT GTGCCAAGCA CGGCCTCAGC 
TACGAAGTGA AGCCCTTCCT CACCGCGCTG GTGGACATCG TCAGGTCCCT GAAGAAGTCT 
GGTGACATCT GGCTGGACGC CTACCTCCAT CAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FADS3 ( XM_017017723.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016873212.1 Homo sapiens fatty acid desaturase 3 (FADS3), transcript variant X1, mRNA.

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CloneID	OHu92225
Clone ID Related Accession (Same CDS sequence)	XM_017017723.1
Accession Version	XM_017017723.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1503bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	fatty acid desaturase 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATGGCA GCGCCCGCCT CCACGCGCCA GTGCCCTCCT GCTCCCCTAC CTCCCCCTTG 
GCCACCCCTG GGCATCCCCA GCCCTGCAGC GCCGAGGGCG GAGGGGAGGC CACCCGCCCC 
CAGCAGAGGG CTCCGAGAGA GCTGCAGCGG CGGTGGGGGC CCCGCAGAGA TTGGGGCCCA 
TGGTTTGAAG GCTGTTCACA GGCACCCCGA GACAGCGTCC CCCCTCTGGG CGCACTGGAT 
TTGACGTTGC AGGACGCGCG GCTGGAAGCC CCCCAGGCCC CGCTGCTCAC AGACCGGGAC 
TCCGCCTCCG GTTCCCGAGG GCGTGGCGAG GCGCTGCGGG ACGCCCAACA GGATGCCTTC 
CGTGCCTTCC ATCAAGATCT CAATTTTGTG CGCAAGTTCC TACAGCCCCT GTTGATTGGA 
GAGCTGGCTC CGGAAGAACC CAGCCAGGAT GGACCCCTGA ATGCGCAGCT GGTCGAGGAC 
TTCCGAGCCC TGCACCAGGC AGCCGAGGAC ATGAAGCTGT TTGATGCCAG TCCCACCTTC 
TTTGCTTTCC TACTGGGCCA CATCCTGGCC ATGGAGGTGC TGGCCTGGCT CCTTATCTAC 
CTCCTGGGTC CTGGCTGGGT GCCCAGTGCC CTGGCCGCCT TCATCCTGGC CATCTCTCAG 
GCTCAGTCCT GGTGTCTGCA GCATGACCTG GGCCATGCCT CCATCTTCAA GAAGTCCTGG 
TGGAACCACG TGGCCCAGAA GTTCGTGATG GGGCAGCTAA AGGGCTTCTC CGCCCACTGG 
TGGAACTTCC GCCACTTCCA GCACCACGCC AAGCCCAACA TCTTCCACAA AGACCCAGAC 
GTGACGGTGG CGCCCGTCTT CCTCCTGGGG GAGTCATCCG TCGAGTATGG CAAGAAGAAA 
CGCAGATACC TACCCTACAA CCAGCAGCAC CTGTACTTCT TCCTGATCGG CCCGCCGCTG 
CTCACCCTGG TGAACTTTGA AGTGGAAAAT CTGGCGTACA TGCTGGTGTG CATGCAGTGG 
GCGGATTTGC TCTGGGCCGC CAGCTTCTAT GCCCGCTTCT TCTTATCCTA CCTCCCCTTC 
TACGGCGTCC CTGGGGTGCT GCTCTTCTTT GTTGCTGTCA GGGTCCTGGA AAGCCACTGG 
TTCGTGTGGA TCACACAGAT GAACCACATC CCCAAGGAGA TCGGCCACGA GAAGCACCGG 
GACTGGGTCA GCTCTCAGCT GGCAGCCACC TGCAACGTGG AGCCCTCACT TTTCACCAAC 
TGGTTCAGCG GGCACCTCAA CTTCCAGATC GAGCACCAGT GCCAGCATAC GCTCCCCACC 
CCCAGCCTCT TCCCCAGGAT GCCGAGACAC AACTACAGCC GGGTGGCCCC GCTGGTCAAG 
TCGCTGTGTG CCAAGCACGG CCTCAGCTAC GAAGTGAAGC CCTTCCTCAC CGCGCTGGTG 
GACATCGTCA GGTCCCTGAA GAAGTCTGGT GACATCTGGC TGGACGCCTA CCTCCATCAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016873212.1
CDS	16..1518
Translation	MDGSARLHAPVPSCSPTSPLATPGHPQPCSAEGGGEATRPQQRAPRELQRRWGPRRDWGPWFEGCSQAPRDSVPPLGALDLTLQDARLEAPQAPLLTDRDSASGSRGRGEALRDAQQDAFRAFHQDLNFVRKFLQPLLIGELAPEEPSQDGPLNAQLVEDFRALHQAAEDMKLFDASPTFFAFLLGHILAMEVLAWLLIYLLGPGWVPSALAAFILAISQAQSWCLQHDLGHASIFKKSWWNHVAQKFVMGQLKGFSAHWWNFRHFQHHAKPNIFHKDPDVTVAPVFLLGESSVEYGKKKRRYLPYNQQHLYFFLIGPPLLTLVNFEVENLAYMLVCMQWADLLWAASFYARFFLSYLPFYGVPGVLLFFVAVRVLESHWFVWITQMNHIPKEIGHEKHRDWVSSQLAATCNVEPSLFTNWFSGHLNFQIEHQCQHTLPTPSLFPRMPRHNYSRVAPLVKSLCAKHGLSYEVKPFLTALVDIVRSLKKSGDIWLDAYLHQ

Target ORF information:

RefSeq Version	XM_017017723.1
Organism	Homo sapiens(human)
Definition	Homo sapiens fatty acid desaturase 3 (FADS3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017017723.1

ORF Insert Sequence:

ATGGATGGCA GCGCCCGCCT CCACGCGCCA GTGCCCTCCT GCTCCCCTAC CTCCCCCTTG 
GCCACCCCTG GGCATCCCCA GCCCTGCAGC GCCGAGGGCG GAGGGGAGGC CACCCGCCCC 
CAGCAGAGGG CTCCGAGAGA GCTGCAGCGG CGGTGGGGGC CCCGCAGAGA TTGGGGCCCA 
TGGTTTGAAG GCTGTTCACA GGCACCCCGA GACAGCGTCC CCCCTCTGGG CGCACTGGAT 
TTGACGTTGC AGGACGCGCG GCTGGAAGCC CCCCAGGCCC CGCTGCTCAC AGACCGGGAC 
TCCGCCTCCG GTTCCCGAGG GCGTGGCGAG GCGCTGCGGG ACGCCCAACA GGATGCCTTC 
CGTGCCTTCC ATCAAGATCT CAATTTTGTG CGCAAGTTCC TACAGCCCCT GTTGATTGGA 
GAGCTGGCTC CGGAAGAACC CAGCCAGGAT GGACCCCTGA ATGCGCAGCT GGTCGAGGAC 
TTCCGAGCCC TGCACCAGGC AGCCGAGGAC ATGAAGCTGT TTGATGCCAG TCCCACCTTC 
TTTGCTTTCC TACTGGGCCA CATCCTGGCC ATGGAGGTGC TGGCCTGGCT CCTTATCTAC 
CTCCTGGGTC CTGGCTGGGT GCCCAGTGCC CTGGCCGCCT TCATCCTGGC CATCTCTCAG 
GCTCAGTCCT GGTGTCTGCA GCATGACCTG GGCCATGCCT CCATCTTCAA GAAGTCCTGG 
TGGAACCACG TGGCCCAGAA GTTCGTGATG GGGCAGCTAA AGGGCTTCTC CGCCCACTGG 
TGGAACTTCC GCCACTTCCA GCACCACGCC AAGCCCAACA TCTTCCACAA AGACCCAGAC 
GTGACGGTGG CGCCCGTCTT CCTCCTGGGG GAGTCATCCG TCGAGTATGG CAAGAAGAAA 
CGCAGATACC TACCCTACAA CCAGCAGCAC CTGTACTTCT TCCTGATCGG CCCGCCGCTG 
CTCACCCTGG TGAACTTTGA AGTGGAAAAT CTGGCGTACA TGCTGGTGTG CATGCAGTGG 
GCGGATTTGC TCTGGGCCGC CAGCTTCTAT GCCCGCTTCT TCTTATCCTA CCTCCCCTTC 
TACGGCGTCC CTGGGGTGCT GCTCTTCTTT GTTGCTGTCA GGGTCCTGGA AAGCCACTGG 
TTCGTGTGGA TCACACAGAT GAACCACATC CCCAAGGAGA TCGGCCACGA GAAGCACCGG 
GACTGGGTCA GCTCTCAGCT GGCAGCCACC TGCAACGTGG AGCCCTCACT TTTCACCAAC 
TGGTTCAGCG GGCACCTCAA CTTCCAGATC GAGCACCAGT GCCAGCATAC GCTCCCCACC 
CCCAGCCTCT TCCCCAGGAT GCCGAGACAC AACTACAGCC GGGTGGCCCC GCTGGTCAAG 
TCGCTGTGTG CCAAGCACGG CCTCAGCTAC GAAGTGAAGC CCTTCCTCAC CGCGCTGGTG 
GACATCGTCA GGTCCCTGAA GAAGTCTGGT GACATCTGGC TGGACGCCTA CCTCCATCAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FADS3 ( XM_011545023.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011543325.1 Homo sapiens fatty acid desaturase 3 (FADS3), transcript variant X3, mRNA.

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CloneID	OHu58726
Clone ID Related Accession (Same CDS sequence)	XM_011545023.2
Accession Version	XM_011545023.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1365bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	fatty acid desaturase 3 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011545023.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCGGCG TCGGGGAGCC GGGACCGCGG GAGGGACCCG CGCAGCCGGG GGCGCCGCTG 
CCCACCTTCT GCTGGGAGCA GATCCGCGCG CACGACCAGC CCGGCGACAA GTGGCTGGTC 
ATCGAGCGCC GCGTCTACGA CATCAGCCGC TGGGCACAGC GGCACCCAGG GGGCAGCCGC 
CTCATCGGCC ACCACGGCGC TGAGGACGCC ACGGATGCCT TCCGTGCCTT CCATCAAGAT 
CTCAATTTTG TGCGCAAGTT CCTACAGCCC CTGTTGATTG GAGAGCTGGC TCCGGAAGAA 
CCCAGCCAGG ATGGACCCCT GAATGCGCAG CTGGTCGAGG ACTTCCGAGC CCTGCACCAG 
GCAGCCGAGG ACATGAAGCT GTTTGATGCC AGTCCCACCT TCTTTGCTTT CCTACTGGGC 
CACATCCTGG CCATGGAGGT GCTGGCCTGG CTCCTTATCT ACCTCCTGGG TCCTGGCTGG 
GTGCCCAGTG CCCTGGCCGC CTTCATCCTG GCCATCTCTC AGGCTCAGTC CTGGTGTCTG 
CAGCATGACC TGGGCCATGC CTCCATCTTC AAGAAGTCCT GGTGGAACCA CGTGGCCCAG 
AAGTTCGTGA TGGGGCAGCT AAAGGGCTTC TCCGCCCACT GGTGGAACTT CCGCCACTTC 
CAGCACCACG CCAAGCCCAA CATCTTCCAC AAAGACCCAG ACGTGACGGT GGCGCCCGTC 
TTCCTCCTGG GGGAGTCATC CGTCGAGTAT GGCAAGAAGA AACGCAGATA CCTACCCTAC 
AACCAGCAGC ACCTGTACTT CTTCCTGATC GGCCCGCCGC TGCTCACCCT GGTGAACTTT 
GAAGTGGAAA ATCTGGCGTA CATGCTGGTG TGCATGCAGT GGGCGGATTT GCTCTGGGCC 
GCCAGCTTCT ATGCCCGCTT CTTCTTATCC TACCTCCCCT TCTACGGCGT CCCTGGGGTG 
CTGCTCTTCT TTGTTGCTGT CAGGGTCCTG GAAAGCCACT GGTTCGTGTG GATCACACAG 
ATGAACCACA TCCCCAAGGA GATCGGCCAC GAGAAGCACC GGGACTGGGT CAGCTCTCAG 
CTGGCAGCCA CCTGCAACGT GGAGCCCTCA CTTTTCACCA ACTGGTTCAG CGGGCACCTC 
AACTTCCAGA TCGAGCACCA GTGCCAGCAT ACGCTCCCCA CCCCCAGCCT CTTCCCCAGG 
ATGCCGAGAC ACAACTACAG CCGGGTGGCC CCGCTGGTCA AGTCGCTGTG TGCCAAGCAC 
GGCCTCAGCT ACGAAGTGAA GCCCTTCCTC ACCGCGCTGG TGGACATCGT CAGGTCCCTG 
AAGAAGTCTG GTGACATCTG GCTGGACGCC TACCTCCATC AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011543325.1
CDS	165..1529
Translation	MGGVGEPGPREGPAQPGAPLPTFCWEQIRAHDQPGDKWLVIERRVYDISRWAQRHPGGSRLIGHHGAEDATDAFRAFHQDLNFVRKFLQPLLIGELAPEEPSQDGPLNAQLVEDFRALHQAAEDMKLFDASPTFFAFLLGHILAMEVLAWLLIYLLGPGWVPSALAAFILAISQAQSWCLQHDLGHASIFKKSWWNHVAQKFVMGQLKGFSAHWWNFRHFQHHAKPNIFHKDPDVTVAPVFLLGESSVEYGKKKRRYLPYNQQHLYFFLIGPPLLTLVNFEVENLAYMLVCMQWADLLWAASFYARFFLSYLPFYGVPGVLLFFVAVRVLESHWFVWITQMNHIPKEIGHEKHRDWVSSQLAATCNVEPSLFTNWFSGHLNFQIEHQCQHTLPTPSLFPRMPRHNYSRVAPLVKSLCAKHGLSYEVKPFLTALVDIVRSLKKSGDIWLDAYLHQ

Target ORF information:

RefSeq Version	XM_011545023.2
Organism	Homo sapiens(human)
Definition	Homo sapiens fatty acid desaturase 3 (FADS3), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011545023.2

ORF Insert Sequence:

ATGGGCGGCG TCGGGGAGCC GGGACCGCGG GAGGGACCCG CGCAGCCGGG GGCGCCGCTG 
CCCACCTTCT GCTGGGAGCA GATCCGCGCG CACGACCAGC CCGGCGACAA GTGGCTGGTC 
ATCGAGCGCC GCGTCTACGA CATCAGCCGC TGGGCACAGC GGCACCCAGG GGGCAGCCGC 
CTCATCGGCC ACCACGGCGC TGAGGACGCC ACGGATGCCT TCCGTGCCTT CCATCAAGAT 
CTCAATTTTG TGCGCAAGTT CCTACAGCCC CTGTTGATTG GAGAGCTGGC TCCGGAAGAA 
CCCAGCCAGG ATGGACCCCT GAATGCGCAG CTGGTCGAGG ACTTCCGAGC CCTGCACCAG 
GCAGCCGAGG ACATGAAGCT GTTTGATGCC AGTCCCACCT TCTTTGCTTT CCTACTGGGC 
CACATCCTGG CCATGGAGGT GCTGGCCTGG CTCCTTATCT ACCTCCTGGG TCCTGGCTGG 
GTGCCCAGTG CCCTGGCCGC CTTCATCCTG GCCATCTCTC AGGCTCAGTC CTGGTGTCTG 
CAGCATGACC TGGGCCATGC CTCCATCTTC AAGAAGTCCT GGTGGAACCA CGTGGCCCAG 
AAGTTCGTGA TGGGGCAGCT AAAGGGCTTC TCCGCCCACT GGTGGAACTT CCGCCACTTC 
CAGCACCACG CCAAGCCCAA CATCTTCCAC AAAGACCCAG ACGTGACGGT GGCGCCCGTC 
TTCCTCCTGG GGGAGTCATC CGTCGAGTAT GGCAAGAAGA AACGCAGATA CCTACCCTAC 
AACCAGCAGC ACCTGTACTT CTTCCTGATC GGCCCGCCGC TGCTCACCCT GGTGAACTTT 
GAAGTGGAAA ATCTGGCGTA CATGCTGGTG TGCATGCAGT GGGCGGATTT GCTCTGGGCC 
GCCAGCTTCT ATGCCCGCTT CTTCTTATCC TACCTCCCCT TCTACGGCGT CCCTGGGGTG 
CTGCTCTTCT TTGTTGCTGT CAGGGTCCTG GAAAGCCACT GGTTCGTGTG GATCACACAG 
ATGAACCACA TCCCCAAGGA GATCGGCCAC GAGAAGCACC GGGACTGGGT CAGCTCTCAG 
CTGGCAGCCA CCTGCAACGT GGAGCCCTCA CTTTTCACCA ACTGGTTCAG CGGGCACCTC 
AACTTCCAGA TCGAGCACCA GTGCCAGCAT ACGCTCCCCA CCCCCAGCCT CTTCCCCAGG 
ATGCCGAGAC ACAACTACAG CCGGGTGGCC CCGCTGGTCA AGTCGCTGTG TGCCAAGCAC 
GGCCTCAGCT ACGAAGTGAA GCCCTTCCTC ACCGCGCTGG TGGACATCGT CAGGTCCCTG 
AAGAAGTCTG GTGACATCTG GCTGGACGCC TACCTCCATC AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Association of the FADS gene cluster with coronary artery disease and plasma lipid concentrations in the northern Chinese Han population.
Prostaglandins, leukotrienes, and essential fatty acids11711-16(2017 Feb)
Wu Y,Zeng L,Chen X,Xu Y,Ye L,Qin L,Chen L,Xie L

Association of polyunsaturated fatty acids in breast milk with fatty acid desaturase gene polymorphisms among Chinese lactating mothers.
Prostaglandins, leukotrienes, and essential fatty acids10966-71(2016 06)
Ding Z,Liu GL,Li X,Chen XY,Wu YX,Cui CC,Zhang X,Yang G,Xie L

Genome-wide association study identifies three susceptibility loci for laryngeal squamous cell carcinoma in the Chinese population.
Nature genetics46(10)1110-4(2014 Oct)
Wei Q,Yu D,Liu M,Wang M,Zhao M,Liu M,Jia W,Ma H,Fang J,Xu W,Chen K,Xu Z,Wang J,Tian L,Yuan H,Chang J,Hu Z,Wei L,Huang Y,Han Y,Liu J,Han D,Shen H,Yang S,Zheng H,Ji Q,Li D,Tan W,Wu C,Lin D

Genetic variants in desaturase gene, erythrocyte fatty acids, and risk for type 2 diabetes in Chinese Hans.
Nutrition (Burbank, Los Angeles County, Calif.)30(7-8)897-902(2014 Jul-Aug)
Huang T,Sun J,Chen Y,Xie H,Xu D,Huang J,Li D

Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium.
Circulation. Cardiovascular genetics7(3)321-331(2014 Jun)
Guan W,Steffen BT,Lemaitre RN,Wu JHY,Tanaka T,Manichaikul A,Foy M,Rich SS,Wang L,Nettleton JA,Tang W,Gu X,Bandinelli S,King IB,McKnight B,Psaty BM,Siscovick D,Djousse L,Chen YI,Ferrucci L,Fornage M,Mozafarrian D,Tsai MY,Steffen LM

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FADS3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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