OR51B6 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	OR51B6
Entrez Gene ID	390058
Full Name	olfactory receptor family 51 subfamily B member 6
Synonyms	HOR5'Beta6
General protein information	Preferred Names olfactory receptor family 51 subfamily B member 6 Names olfactory receptor 51B6 odorant receptor HOR5'beta6 olfactory receptor 51B5
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11p15.4
Summary	Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001004750.1	NP_001004750.1	olfactory receptor 51B6

Pathways from BioSystems

Homologies

Homo sapiens (human)	OR51B6	NP_001004750.1
Rattus norvegicus (Norway rat)	Olr132	NP_001001273.1
Pan troglodytes (chimpanzee)	LOC466375	XP_521774.2
Mus musculus (house mouse)	Olfr65	NP_038644.2
Canis lupus familiaris (dog)	LOC100683227	XP_003433027.2

Gene Ontology
Bibliography

Related articles in PubMed

Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster.
Solovieff N, Milton JN, Hartley SW, Sherva R, Sebastiani P, Dworkis DA, Klings ES, Farrer LA, Garrett ME, Ashley-Koch A, Telen MJ, Fucharoen S, Ha SY, Li CK, Chui DH, Baldwin CT, Steinberg MH
Blood115(9)1815-22(2010 Mar)

Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters.
Bulger M, Bender MA, van Doorninck JH, Wertman B, Farrell CM, Felsenfeld G, Groudine M, Hardison R
Proceedings of the National Academy of Sciences of the United States of America97(26)14560-5(2000 Dec)

Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes.
Bulger M, van Doorninck JH, Saitoh N, Telling A, Farrell C, Bender MA, Felsenfeld G, Axel R, Groudine M, von Doorninck JH
Proceedings of the National Academy of Sciences of the United States of America96(9)5129-34(1999 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
Title: Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster.

The following OR51B6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the OR51B6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu29479	NM_001004750.1 Latest version!	Homo sapiens olfactory receptor family 51 subfamily B member 6 (OR51B6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

OR51B6 ( NM_001004750.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001004750.1 Homo sapiens olfactory receptor family 51 subfamily B member 6 (OR51B6), mRNA.

Price & Availability↑

CloneID	OHu29479
Clone ID Related Accession (Same CDS sequence)	NM_001004750.1
Accession Version	NM_001004750.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 939bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-29
Organism	Homo sapiens(human)
Product	olfactory receptor 51B6
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC104389.8. On Sep 22, 2004 this sequence version replaced XM_372353.1. ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000380219.1/ ENSP00000369568.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGGGGCTCA ATAAGTCTGC TTCCACCTTC CAGCTTACTG GCTTCCCAGG CATGGAGAAG 
GCACATCACT GGATATTCAT CCCATTATTG GCAGCCTACA TCTCCATACT TCTTGGCAAT 
GGCACTCTTC TCTTTCTCAT CAGGAATGAT CATAACCTCC ATGAGCCCAT GTACTATTTC 
TTAGCTATGT TGGCAGCTAC AGACCTCGGA GTGACATTGA CCACAATGCC CACAGTGCTA 
GGTGTTCTGT GGTTAGATCA CAGGGAGATT GGCCATGGAG CCTGCTTCTC TCAGGCCTAT 
TTTATCCATA CTCTTTCTGT CATGGAGTCA GGTGTCTTGC TTGCCATGGC TTATGACTGT 
TTCATTACCA TCCGCAGCCC CTTAAGATAT ACCTCTATCC TGACCAACAC CCAGGTAATG 
AAGATTGGTG TGCGGGTATT GACAAGGGCT GGTCTGTCCA TTATGCCAAT AGTTGTTCGC 
CTACACTGGT TTCCCTACTG TCGATCCCAT GTACTCTCCC ATGCTTTCTG TCTACACCAA 
GATGTCATCA AGCTAGCCTG TGCTGACATC ACCTTCAACC GTCTCTATCC AGTTGTAGTT 
TTATTTGCAA TGGTCTTGTT GGACTTTCTC ATCATCTTTT TCTCCTACAT TTTGATTCTC 
AAGACTGTCA TGGGCATTGG TTCTGGAGGA GAAAGGGCCA AGGCCCTCAA CACATGTGTC 
TCTCATATCT GCTGCATCCT GGTCTTCTAT GTCACTGTAG TTTGTCTGAC ATTTATTCAT 
AGGTTTGGAA AGCATGTTCC TCATGTCGTT CACATCACAA TGAGCTACAT CCACTTCCTT 
TTCCCACCTT TTATGAACCC ATTTATCTAT AGCATTAAAA CTAAGCAGAT TCAGAGTGGC 
ATACTTCGTT TATTCTCTCT GCCTCACTCT AGAGCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001004750.1
CDS	1..939
Translation	MGLNKSASTFQLTGFPGMEKAHHWIFIPLLAAYISILLGNGTLLFLIRNDHNLHEPMYYFLAMLAATDLGVTLTTMPTVLGVLWLDHREIGHGACFSQAYFIHTLSVMESGVLLAMAYDCFITIRSPLRYTSILTNTQVMKIGVRVLTRAGLSIMPIVVRLHWFPYCRSHVLSHAFCLHQDVIKLACADITFNRLYPVVVLFAMVLLDFLIIFFSYILILKTVMGIGSGGERAKALNTCVSHICCILVFYVTVVCLTFIHRFGKHVPHVVHITMSYIHFLFPPFMNPFIYSIKTKQIQSGILRLFSLPHSRA

Target ORF information:

RefSeq Version	NM_001004750.1
Organism	Homo sapiens(human)
Definition	Homo sapiens olfactory receptor family 51 subfamily B member 6 (OR51B6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001004750.1

ORF Insert Sequence:

ATGGGGCTCA ATAAGTCTGC TTCCACCTTC CAGCTTACTG GCTTCCCAGG CATGGAGAAG 
GCACATCACT GGATATTCAT CCCATTATTG GCAGCCTACA TCTCCATACT TCTTGGCAAT 
GGCACTCTTC TCTTTCTCAT CAGGAATGAT CATAACCTCC ATGAGCCCAT GTACTATTTC 
TTAGCTATGT TGGCAGCTAC AGACCTCGGA GTGACATTGA CCACAATGCC CACAGTGCTA 
GGTGTTCTGT GGTTAGATCA CAGGGAGATT GGCCATGGAG CCTGCTTCTC TCAGGCCTAT 
TTTATCCATA CTCTTTCTGT CATGGAGTCA GGTGTCTTGC TTGCCATGGC TTATGACTGT 
TTCATTACCA TCCGCAGCCC CTTAAGATAT ACCTCTATCC TGACCAACAC CCAGGTAATG 
AAGATTGGTG TGCGGGTATT GACAAGGGCT GGTCTGTCCA TTATGCCAAT AGTTGTTCGC 
CTACACTGGT TTCCCTACTG TCGATCCCAT GTACTCTCCC ATGCTTTCTG TCTACACCAA 
GATGTCATCA AGCTAGCCTG TGCTGACATC ACCTTCAACC GTCTCTATCC AGTTGTAGTT 
TTATTTGCAA TGGTCTTGTT GGACTTTCTC ATCATCTTTT TCTCCTACAT TTTGATTCTC 
AAGACTGTCA TGGGCATTGG TTCTGGAGGA GAAAGGGCCA AGGCCCTCAA CACATGTGTC 
TCTCATATCT GCTGCATCCT GGTCTTCTAT GTCACTGTAG TTTGTCTGAC ATTTATTCAT 
AGGTTTGGAA AGCATGTTCC TCATGTCGTT CACATCACAA TGAGCTACAT CCACTTCCTT 
TTCCCACCTT TTATGAACCC ATTTATCTAT AGCATTAAAA CTAAGCAGAT TCAGAGTGGC 
ATACTTCGTT TATTCTCTCT GCCTCACTCT AGAGCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster.
Blood115(9)1815-22(2010 Mar)
Solovieff N,Milton JN,Hartley SW,Sherva R,Sebastiani P,Dworkis DA,Klings ES,Farrer LA,Garrett ME,Ashley-Koch A,Telen MJ,Fucharoen S,Ha SY,Li CK,Chui DH,Baldwin CT,Steinberg MH

Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters.
Proceedings of the National Academy of Sciences of the United States of America97(26)14560-5(2000 Dec)
Bulger M,Bender MA,van Doorninck JH,Wertman B,Farrell CM,Felsenfeld G,Groudine M,Hardison R

Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes.
Proceedings of the National Academy of Sciences of the United States of America96(9)5129-34(1999 Apr)
Bulger M,van Doorninck JH,Saitoh N,Telling A,Farrell C,Bender MA,Felsenfeld G,Axel R,Groudine M,von Doorninck JH

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OR51B6 cDNA ORF clone, Homo sapiens(human)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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