Gene Symbol | USP27X |
Entrez Gene ID | 389856 |
Full Name | ubiquitin specific peptidase 27, X-linked |
Synonyms | MRX105,USP22L,USP27 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a member of the peptidase protein family. The encoded protein functions as a deubiquitinase that is involved in upregulation of the pro-apoptotic Bim protein. This protein may act as a tumor suppressor by increasing levels of Bim to counteract anti-apoptotic signals in cancer cells. Mutations in this gene have been associated with X-linked cognitive disability. [provided by RefSeq, Dec 2016]. |
Disorder MIM: | |
Disorder Html: | Mental retardation 105, 300984 (3) |