KPNB1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	KPNB1
Entrez Gene ID	3837
Full Name	karyopherin subunit beta 1
Synonyms	IMB1,IPO1,IPOB,Impnb,NTF97
General protein information	Preferred Names karyopherin subunit beta 1 Names importin subunit beta-1 PTAC97 importin 1 importin 90 importin beta-1 subunit karyopherin (importin) beta 1 nuclear factor p97 pore targeting complex 97 kDa subunit
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q21.32
Summary	Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013].
Disorder MIM:	602738

mRNA and Protein(s)

mRNA	Protein	Name
NM_001276453.1	NP_001263382.1	importin subunit beta-1 isoform 2
NM_002265.5	NP_002256.2	importin subunit beta-1 isoform 1
NM_002265.6	NP_002256.2	importin subunit beta-1 isoform 1
NM_001276453.2	NP_001263382.1	importin subunit beta-1 isoform 2

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	KPNB1	XP_004950071.1
Caenorhabditis elegans (roundworm)	imb-1	NP_491477.2
Kluyveromyces lactis	KLLA0B05665g	XP_451788.1
Homo sapiens (human)	KPNB1	NP_002256.2
Bos taurus (cattle)	KPNB1	NP_001180082.1
Mus musculus (house mouse)	Kpnb1	NP_032405.3
Drosophila melanogaster (fruit fly)	Fs(2)Ket	NP_001246109.1
Neurospora crassa	NCU02011	XP_964876.1
Oryza sativa (rice)	Os12g0568800	NP_001067068.1
Saccharomyces cerevisiae (baker's yeast)	KAP95	NP_013451.1
Schizosaccharomyces pombe (fission yeast)	kap95	NP_594233.1
Pan troglodytes (chimpanzee)	KPNB1	XP_003315429.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009921	XP_319040.3
Arabidopsis thaliana (thale cress)	AT5G53480	NP_200160.1
Xenopus tropicalis (tropical clawed frog)	kpnb1	XP_002940197.1
	KPNB1	XP_001082833.2
Canis lupus familiaris (dog)	KPNB1	XP_005624657.1
Rattus norvegicus (Norway rat)	Kpnb1	NP_058759.1
Danio rerio (zebrafish)	kpnb1	NP_001032791.2
Eremothecium gossypii	AGOS_ACL187W	NP_983217.2
Magnaporthe oryzae (rice blast fungus)	MGG_03668	XP_003716218.1

Gene Ontology

The following KPNB1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KPNB1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu09855	NM_001276453.2 Latest version!	Homo sapiens karyopherin subunit beta 1 (KPNB1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu10409	NM_002265.6 Latest version!	Homo sapiens karyopherin subunit beta 1 (KPNB1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu10409	NM_002265.5	Homo sapiens karyopherin subunit beta 1 (KPNB1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu09855	NM_001276453.1	Homo sapiens karyopherin subunit beta 1 (KPNB1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KPNB1 ( NM_001276453.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001263382.1 Homo sapiens karyopherin subunit beta 1 (KPNB1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu09855
Clone ID Related Accession (Same CDS sequence)	NM_001276453.1 , NM_001276453.2
Accession Version	NM_001276453.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2196bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-03
Organism	Homo sapiens(human)
Product	importin subunit beta-1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK301463.1, BC036703.2, BQ009884.1, AC015674.12 and AI076614.1. Transcript Variant: This variant (2) has an alternate exon in place of the first two exons compared to variant 1, which causes translation to begin at a downstream AUG compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK301463.1, SRR1660807.237672.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGGAGT CGACATTGGA AGCCATCGGT TATATTTGCC AAGATATAGA CCCAGAGCAG 
CTACAAGATA AATCCAATGA GATTCTGACT GCCATAATCC AGGGGATGAG GAAAGAAGAG 
CCTAGTAATA ATGTGAAGCT AGCTGCTACG AATGCACTCC TGAACTCATT GGAGTTCACC 
AAAGCAAACT TTGATAAAGA GTCTGAAAGG CACTTTATTA TGCAGGTGGT CTGTGAAGCC 
ACACAGTGTC CAGATACGAG GGTACGAGTG GCTGCTTTAC AGAATCTGGT GAAGATAATG 
TCCTTATATT ATCAGTACAT GGAGACATAT ATGGGTCCTG CTCTTTTTGC AATCACAATC 
GAAGCAATGA AAAGTGACAT TGATGAGGTG GCTTTACAAG GGATAGAATT CTGGTCCAAT 
GTCTGTGATG AGGAAATGGA TTTGGCCATT GAAGCTTCAG AGGCAGCAGA ACAAGGACGG 
CCCCCTGAGC ACACCAGCAA GTTTTATGCG AAGGGAGCAC TACAGTATCT GGTTCCAATC 
CTCACACAGA CACTAACTAA ACAGGACGAA AATGATGATG ACGATGACTG GAACCCCTGC 
AAAGCAGCAG GGGTGTGCCT CATGCTTCTG GCCACCTGCT GTGAAGATGA CATTGTCCCA 
CATGTCCTCC CCTTCATTAA AGAACACATC AAGAACCCAG ATTGGCGGTA CCGGGATGCA 
GCAGTGATGG CTTTTGGTTG TATCTTGGAA GGACCAGAGC CCAGTCAGCT CAAACCACTA 
GTTATACAGG CTATGCCCAC CCTAATAGAA TTAATGAAAG ACCCCAGTGT AGTTGTTCGA 
GATACAGCTG CATGGACTGT AGGCAGAATT TGTGAGCTGC TTCCTGAAGC TGCCATCAAT 
GATGTCTACT TGGCTCCCCT GCTACAGTGT CTGATTGAGG GTCTCAGTGC TGAACCCAGA 
GTGGCTTCAA ATGTGTGCTG GGCTTTCTCC AGTCTGGCTG AAGCTGCTTA TGAAGCTGCA 
GACGTTGCTG ATGATCAGGA AGAACCAGCT ACTTACTGCT TATCTTCTTC ATTTGAACTC 
ATAGTTCAGA AGCTCCTAGA GACTACAGAC AGACCTGATG GACACCAGAA CAACCTGAGG 
AGTTCTGCAT ATGAATCTCT GATGGAAATT GTGAAAAACA GTGCCAAGGA TTGTTATCCT 
GCTGTCCAGA AAACGACTTT GGTCATCATG GAACGACTGC AACAGGTTCT TCAGATGGAG 
TCACATATCC AGAGCACATC CGATAGAATC CAGTTCAATG ACCTTCAGTC TTTACTCTGT 
GCAACTCTTC AGAATGTTCT TCGGAAAGTG CAACATCAAG ATGCTTTGCA GATCTCTGAT 
GTGGTTATGG CCTCCCTGTT AAGGATGTTC CAAAGCACAG CTGGGTCTGG GGGAGTACAA 
GAGGATGCCC TGATGGCAGT TAGCACACTG GTGGAAGTGT TGGGTGGTGA ATTCCTCAAG 
TACATGGAGG CCTTTAAACC CTTCCTGGGC ATTGGATTAA AAAATTATGC TGAATACCAG 
GTTTGTTTGG CAGCTGTGGG CTTAGTGGGA GACTTGTGCC GTGCCCTGCA ATCCAACATC 
ATACCTTTCT GTGACGAGGT GATGCAGCTG CTTCTGGAAA ATTTGGGGAA TGAGAACGTC 
CACAGGTCTG TGAAGCCGCA GATTCTGTCA GTGTTTGGTG ATATTGCCCT TGCTATTGGA 
GGAGAGTTTA AAAAATACTT AGAGGTTGTA TTGAATACTC TTCAGCAGGC CTCCCAAGCC 
CAGGTGGACA AGTCAGACTA TGACATGGTG GATTATCTGA ATGAGCTAAG GGAAAGCTGC 
TTGGAAGCCT ATACTGGAAT CGTCCAGGGA TTAAAGGGGG ATCAGGAGAA CGTACACCCG 
GATGTGATGC TGGTACAACC CAGAGTAGAA TTTATTCTGT CTTTCATTGA CCACATTGCT 
GGAGATGAGG ATCACACAGA TGGAGTAGTA GCTTGTGCTG CTGGACTAAT AGGGGACTTA 
TGTACAGCAT TTGGGAAGGA TGTACTGAAA TTAGTAGAAG CTAGGCCAAT GATCCATGAA 
TTGTTAACTG AAGGGCGGAG ATCGAAGACT AACAAAGCAA AAACCCTTGC TACATGGGCA 
ACAAAAGAAC TGAGGAAACT GAAGAACCAA GCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001263382.1
CDS	518..2713
Translation	MKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIMQVVCEATQCPDTRVRVAALQNLVKIMSLYYQYMETYMGPALFAITIEAMKSDIDEVALQGIEFWSNVCDEEMDLAIEASEAAEQGRPPEHTSKFYAKGALQYLVPILTQTLTKQDENDDDDDWNPCKAAGVCLMLLATCCEDDIVPHVLPFIKEHIKNPDWRYRDAAVMAFGCILEGPEPSQLKPLVIQAMPTLIELMKDPSVVVRDTAAWTVGRICELLPEAAINDVYLAPLLQCLIEGLSAEPRVASNVCWAFSSLAEAAYEAADVADDQEEPATYCLSSSFELIVQKLLETTDRPDGHQNNLRSSAYESLMEIVKNSAKDCYPAVQKTTLVIMERLQQVLQMESHIQSTSDRIQFNDLQSLLCATLQNVLRKVQHQDALQISDVVMASLLRMFQSTAGSGGVQEDALMAVSTLVEVLGGEFLKYMEAFKPFLGIGLKNYAEYQVCLAAVGLVGDLCRALQSNIIPFCDEVMQLLLENLGNENVHRSVKPQILSVFGDIALAIGGEFKKYLEVVLNTLQQASQAQVDKSDYDMVDYLNELRESCLEAYTGIVQGLKGDQENVHPDVMLVQPRVEFILSFIDHIAGDEDHTDGVVACAAGLIGDLCTAFGKDVLKLVEARPMIHELLTEGRRSKTNKAKTLATWATKELRKLKNQA

Target ORF information:

RefSeq Version	NM_001276453.1
Organism	Homo sapiens(human)
Definition	Homo sapiens karyopherin subunit beta 1 (KPNB1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001276453.1

ORF Insert Sequence:

ATGAAGGAGT CGACATTGGA AGCCATCGGT TATATTTGCC AAGATATAGA CCCAGAGCAG 
CTACAAGATA AATCCAATGA GATTCTGACT GCCATAATCC AGGGGATGAG GAAAGAAGAG 
CCTAGTAATA ATGTGAAGCT AGCTGCTACG AATGCACTCC TGAACTCATT GGAGTTCACC 
AAAGCAAACT TTGATAAAGA GTCTGAAAGG CACTTTATTA TGCAGGTGGT CTGTGAAGCC 
ACACAGTGTC CAGATACGAG GGTACGAGTG GCTGCTTTAC AGAATCTGGT GAAGATAATG 
TCCTTATATT ATCAGTACAT GGAGACATAT ATGGGTCCTG CTCTTTTTGC AATCACAATC 
GAAGCAATGA AAAGTGACAT TGATGAGGTG GCTTTACAAG GGATAGAATT CTGGTCCAAT 
GTCTGTGATG AGGAAATGGA TTTGGCCATT GAAGCTTCAG AGGCAGCAGA ACAAGGACGG 
CCCCCTGAGC ACACCAGCAA GTTTTATGCG AAGGGAGCAC TACAGTATCT GGTTCCAATC 
CTCACACAGA CACTAACTAA ACAGGACGAA AATGATGATG ACGATGACTG GAACCCCTGC 
AAAGCAGCAG GGGTGTGCCT CATGCTTCTG GCCACCTGCT GTGAAGATGA CATTGTCCCA 
CATGTCCTCC CCTTCATTAA AGAACACATC AAGAACCCAG ATTGGCGGTA CCGGGATGCA 
GCAGTGATGG CTTTTGGTTG TATCTTGGAA GGACCAGAGC CCAGTCAGCT CAAACCACTA 
GTTATACAGG CTATGCCCAC CCTAATAGAA TTAATGAAAG ACCCCAGTGT AGTTGTTCGA 
GATACAGCTG CATGGACTGT AGGCAGAATT TGTGAGCTGC TTCCTGAAGC TGCCATCAAT 
GATGTCTACT TGGCTCCCCT GCTACAGTGT CTGATTGAGG GTCTCAGTGC TGAACCCAGA 
GTGGCTTCAA ATGTGTGCTG GGCTTTCTCC AGTCTGGCTG AAGCTGCTTA TGAAGCTGCA 
GACGTTGCTG ATGATCAGGA AGAACCAGCT ACTTACTGCT TATCTTCTTC ATTTGAACTC 
ATAGTTCAGA AGCTCCTAGA GACTACAGAC AGACCTGATG GACACCAGAA CAACCTGAGG 
AGTTCTGCAT ATGAATCTCT GATGGAAATT GTGAAAAACA GTGCCAAGGA TTGTTATCCT 
GCTGTCCAGA AAACGACTTT GGTCATCATG GAACGACTGC AACAGGTTCT TCAGATGGAG 
TCACATATCC AGAGCACATC CGATAGAATC CAGTTCAATG ACCTTCAGTC TTTACTCTGT 
GCAACTCTTC AGAATGTTCT TCGGAAAGTG CAACATCAAG ATGCTTTGCA GATCTCTGAT 
GTGGTTATGG CCTCCCTGTT AAGGATGTTC CAAAGCACAG CTGGGTCTGG GGGAGTACAA 
GAGGATGCCC TGATGGCAGT TAGCACACTG GTGGAAGTGT TGGGTGGTGA ATTCCTCAAG 
TACATGGAGG CCTTTAAACC CTTCCTGGGC ATTGGATTAA AAAATTATGC TGAATACCAG 
GTTTGTTTGG CAGCTGTGGG CTTAGTGGGA GACTTGTGCC GTGCCCTGCA ATCCAACATC 
ATACCTTTCT GTGACGAGGT GATGCAGCTG CTTCTGGAAA ATTTGGGGAA TGAGAACGTC 
CACAGGTCTG TGAAGCCGCA GATTCTGTCA GTGTTTGGTG ATATTGCCCT TGCTATTGGA 
GGAGAGTTTA AAAAATACTT AGAGGTTGTA TTGAATACTC TTCAGCAGGC CTCCCAAGCC 
CAGGTGGACA AGTCAGACTA TGACATGGTG GATTATCTGA ATGAGCTAAG GGAAAGCTGC 
TTGGAAGCCT ATACTGGAAT CGTCCAGGGA TTAAAGGGGG ATCAGGAGAA CGTACACCCG 
GATGTGATGC TGGTACAACC CAGAGTAGAA TTTATTCTGT CTTTCATTGA CCACATTGCT 
GGAGATGAGG ATCACACAGA TGGAGTAGTA GCTTGTGCTG CTGGACTAAT AGGGGACTTA 
TGTACAGCAT TTGGGAAGGA TGTACTGAAA TTAGTAGAAG CTAGGCCAAT GATCCATGAA 
TTGTTAACTG AAGGGCGGAG ATCGAAGACT AACAAAGCAA AAACCCTTGC TACATGGGCA 
ACAAAAGAAC TGAGGAAACT GAAGAACCAA GCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KPNB1 ( NM_001276453.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001263382.1 Homo sapiens karyopherin subunit beta 1 (KPNB1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu09855
Clone ID Related Accession (Same CDS sequence)	NM_001276453.1 , NM_001276453.2
Accession Version	NM_001276453.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2196bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-20
Organism	Homo sapiens(human)
Product	importin subunit beta-1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC025682.6, AC015674.12 and KF570270.1. On May 31, 2019 this sequence version replaced NM_001276453.1. Transcript Variant: This variant (2) has an alternate exon in place of the first two exons compared to variant 1, which causes translation to begin at a downstream AUG compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.237672.1, SRR1803617.272225.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGGAGT CGACATTGGA AGCCATCGGT TATATTTGCC AAGATATAGA CCCAGAGCAG 
CTACAAGATA AATCCAATGA GATTCTGACT GCCATAATCC AGGGGATGAG GAAAGAAGAG 
CCTAGTAATA ATGTGAAGCT AGCTGCTACG AATGCACTCC TGAACTCATT GGAGTTCACC 
AAAGCAAACT TTGATAAAGA GTCTGAAAGG CACTTTATTA TGCAGGTGGT CTGTGAAGCC 
ACACAGTGTC CAGATACGAG GGTACGAGTG GCTGCTTTAC AGAATCTGGT GAAGATAATG 
TCCTTATATT ATCAGTACAT GGAGACATAT ATGGGTCCTG CTCTTTTTGC AATCACAATC 
GAAGCAATGA AAAGTGACAT TGATGAGGTG GCTTTACAAG GGATAGAATT CTGGTCCAAT 
GTCTGTGATG AGGAAATGGA TTTGGCCATT GAAGCTTCAG AGGCAGCAGA ACAAGGACGG 
CCCCCTGAGC ACACCAGCAA GTTTTATGCG AAGGGAGCAC TACAGTATCT GGTTCCAATC 
CTCACACAGA CACTAACTAA ACAGGACGAA AATGATGATG ACGATGACTG GAACCCCTGC 
AAAGCAGCAG GGGTGTGCCT CATGCTTCTG GCCACCTGCT GTGAAGATGA CATTGTCCCA 
CATGTCCTCC CCTTCATTAA AGAACACATC AAGAACCCAG ATTGGCGGTA CCGGGATGCA 
GCAGTGATGG CTTTTGGTTG TATCTTGGAA GGACCAGAGC CCAGTCAGCT CAAACCACTA 
GTTATACAGG CTATGCCCAC CCTAATAGAA TTAATGAAAG ACCCCAGTGT AGTTGTTCGA 
GATACAGCTG CATGGACTGT AGGCAGAATT TGTGAGCTGC TTCCTGAAGC TGCCATCAAT 
GATGTCTACT TGGCTCCCCT GCTACAGTGT CTGATTGAGG GTCTCAGTGC TGAACCCAGA 
GTGGCTTCAA ATGTGTGCTG GGCTTTCTCC AGTCTGGCTG AAGCTGCTTA TGAAGCTGCA 
GACGTTGCTG ATGATCAGGA AGAACCAGCT ACTTACTGCT TATCTTCTTC ATTTGAACTC 
ATAGTTCAGA AGCTCCTAGA GACTACAGAC AGACCTGATG GACACCAGAA CAACCTGAGG 
AGTTCTGCAT ATGAATCTCT GATGGAAATT GTGAAAAACA GTGCCAAGGA TTGTTATCCT 
GCTGTCCAGA AAACGACTTT GGTCATCATG GAACGACTGC AACAGGTTCT TCAGATGGAG 
TCACATATCC AGAGCACATC CGATAGAATC CAGTTCAATG ACCTTCAGTC TTTACTCTGT 
GCAACTCTTC AGAATGTTCT TCGGAAAGTG CAACATCAAG ATGCTTTGCA GATCTCTGAT 
GTGGTTATGG CCTCCCTGTT AAGGATGTTC CAAAGCACAG CTGGGTCTGG GGGAGTACAA 
GAGGATGCCC TGATGGCAGT TAGCACACTG GTGGAAGTGT TGGGTGGTGA ATTCCTCAAG 
TACATGGAGG CCTTTAAACC CTTCCTGGGC ATTGGATTAA AAAATTATGC TGAATACCAG 
GTTTGTTTGG CAGCTGTGGG CTTAGTGGGA GACTTGTGCC GTGCCCTGCA ATCCAACATC 
ATACCTTTCT GTGACGAGGT GATGCAGCTG CTTCTGGAAA ATTTGGGGAA TGAGAACGTC 
CACAGGTCTG TGAAGCCGCA GATTCTGTCA GTGTTTGGTG ATATTGCCCT TGCTATTGGA 
GGAGAGTTTA AAAAATACTT AGAGGTTGTA TTGAATACTC TTCAGCAGGC CTCCCAAGCC 
CAGGTGGACA AGTCAGACTA TGACATGGTG GATTATCTGA ATGAGCTAAG GGAAAGCTGC 
TTGGAAGCCT ATACTGGAAT CGTCCAGGGA TTAAAGGGGG ATCAGGAGAA CGTACACCCG 
GATGTGATGC TGGTACAACC CAGAGTAGAA TTTATTCTGT CTTTCATTGA CCACATTGCT 
GGAGATGAGG ATCACACAGA TGGAGTAGTA GCTTGTGCTG CTGGACTAAT AGGGGACTTA 
TGTACAGCAT TTGGGAAGGA TGTACTGAAA TTAGTAGAAG CTAGGCCAAT GATCCATGAA 
TTGTTAACTG AAGGGCGGAG ATCGAAGACT AACAAAGCAA AAACCCTTGC TACATGGGCA 
ACAAAAGAAC TGAGGAAACT GAAGAACCAA GCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001263382.1
CDS	649..2844
Translation	MKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIMQVVCEATQCPDTRVRVAALQNLVKIMSLYYQYMETYMGPALFAITIEAMKSDIDEVALQGIEFWSNVCDEEMDLAIEASEAAEQGRPPEHTSKFYAKGALQYLVPILTQTLTKQDENDDDDDWNPCKAAGVCLMLLATCCEDDIVPHVLPFIKEHIKNPDWRYRDAAVMAFGCILEGPEPSQLKPLVIQAMPTLIELMKDPSVVVRDTAAWTVGRICELLPEAAINDVYLAPLLQCLIEGLSAEPRVASNVCWAFSSLAEAAYEAADVADDQEEPATYCLSSSFELIVQKLLETTDRPDGHQNNLRSSAYESLMEIVKNSAKDCYPAVQKTTLVIMERLQQVLQMESHIQSTSDRIQFNDLQSLLCATLQNVLRKVQHQDALQISDVVMASLLRMFQSTAGSGGVQEDALMAVSTLVEVLGGEFLKYMEAFKPFLGIGLKNYAEYQVCLAAVGLVGDLCRALQSNIIPFCDEVMQLLLENLGNENVHRSVKPQILSVFGDIALAIGGEFKKYLEVVLNTLQQASQAQVDKSDYDMVDYLNELRESCLEAYTGIVQGLKGDQENVHPDVMLVQPRVEFILSFIDHIAGDEDHTDGVVACAAGLIGDLCTAFGKDVLKLVEARPMIHELLTEGRRSKTNKAKTLATWATKELRKLKNQA

Target ORF information:

RefSeq Version	NM_001276453.2
Organism	Homo sapiens(human)
Definition	Homo sapiens karyopherin subunit beta 1 (KPNB1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001276453.2

ORF Insert Sequence:

ATGAAGGAGT CGACATTGGA AGCCATCGGT TATATTTGCC AAGATATAGA CCCAGAGCAG 
CTACAAGATA AATCCAATGA GATTCTGACT GCCATAATCC AGGGGATGAG GAAAGAAGAG 
CCTAGTAATA ATGTGAAGCT AGCTGCTACG AATGCACTCC TGAACTCATT GGAGTTCACC 
AAAGCAAACT TTGATAAAGA GTCTGAAAGG CACTTTATTA TGCAGGTGGT CTGTGAAGCC 
ACACAGTGTC CAGATACGAG GGTACGAGTG GCTGCTTTAC AGAATCTGGT GAAGATAATG 
TCCTTATATT ATCAGTACAT GGAGACATAT ATGGGTCCTG CTCTTTTTGC AATCACAATC 
GAAGCAATGA AAAGTGACAT TGATGAGGTG GCTTTACAAG GGATAGAATT CTGGTCCAAT 
GTCTGTGATG AGGAAATGGA TTTGGCCATT GAAGCTTCAG AGGCAGCAGA ACAAGGACGG 
CCCCCTGAGC ACACCAGCAA GTTTTATGCG AAGGGAGCAC TACAGTATCT GGTTCCAATC 
CTCACACAGA CACTAACTAA ACAGGACGAA AATGATGATG ACGATGACTG GAACCCCTGC 
AAAGCAGCAG GGGTGTGCCT CATGCTTCTG GCCACCTGCT GTGAAGATGA CATTGTCCCA 
CATGTCCTCC CCTTCATTAA AGAACACATC AAGAACCCAG ATTGGCGGTA CCGGGATGCA 
GCAGTGATGG CTTTTGGTTG TATCTTGGAA GGACCAGAGC CCAGTCAGCT CAAACCACTA 
GTTATACAGG CTATGCCCAC CCTAATAGAA TTAATGAAAG ACCCCAGTGT AGTTGTTCGA 
GATACAGCTG CATGGACTGT AGGCAGAATT TGTGAGCTGC TTCCTGAAGC TGCCATCAAT 
GATGTCTACT TGGCTCCCCT GCTACAGTGT CTGATTGAGG GTCTCAGTGC TGAACCCAGA 
GTGGCTTCAA ATGTGTGCTG GGCTTTCTCC AGTCTGGCTG AAGCTGCTTA TGAAGCTGCA 
GACGTTGCTG ATGATCAGGA AGAACCAGCT ACTTACTGCT TATCTTCTTC ATTTGAACTC 
ATAGTTCAGA AGCTCCTAGA GACTACAGAC AGACCTGATG GACACCAGAA CAACCTGAGG 
AGTTCTGCAT ATGAATCTCT GATGGAAATT GTGAAAAACA GTGCCAAGGA TTGTTATCCT 
GCTGTCCAGA AAACGACTTT GGTCATCATG GAACGACTGC AACAGGTTCT TCAGATGGAG 
TCACATATCC AGAGCACATC CGATAGAATC CAGTTCAATG ACCTTCAGTC TTTACTCTGT 
GCAACTCTTC AGAATGTTCT TCGGAAAGTG CAACATCAAG ATGCTTTGCA GATCTCTGAT 
GTGGTTATGG CCTCCCTGTT AAGGATGTTC CAAAGCACAG CTGGGTCTGG GGGAGTACAA 
GAGGATGCCC TGATGGCAGT TAGCACACTG GTGGAAGTGT TGGGTGGTGA ATTCCTCAAG 
TACATGGAGG CCTTTAAACC CTTCCTGGGC ATTGGATTAA AAAATTATGC TGAATACCAG 
GTTTGTTTGG CAGCTGTGGG CTTAGTGGGA GACTTGTGCC GTGCCCTGCA ATCCAACATC 
ATACCTTTCT GTGACGAGGT GATGCAGCTG CTTCTGGAAA ATTTGGGGAA TGAGAACGTC 
CACAGGTCTG TGAAGCCGCA GATTCTGTCA GTGTTTGGTG ATATTGCCCT TGCTATTGGA 
GGAGAGTTTA AAAAATACTT AGAGGTTGTA TTGAATACTC TTCAGCAGGC CTCCCAAGCC 
CAGGTGGACA AGTCAGACTA TGACATGGTG GATTATCTGA ATGAGCTAAG GGAAAGCTGC 
TTGGAAGCCT ATACTGGAAT CGTCCAGGGA TTAAAGGGGG ATCAGGAGAA CGTACACCCG 
GATGTGATGC TGGTACAACC CAGAGTAGAA TTTATTCTGT CTTTCATTGA CCACATTGCT 
GGAGATGAGG ATCACACAGA TGGAGTAGTA GCTTGTGCTG CTGGACTAAT AGGGGACTTA 
TGTACAGCAT TTGGGAAGGA TGTACTGAAA TTAGTAGAAG CTAGGCCAAT GATCCATGAA 
TTGTTAACTG AAGGGCGGAG ATCGAAGACT AACAAAGCAA AAACCCTTGC TACATGGGCA 
ACAAAAGAAC TGAGGAAACT GAAGAACCAA GCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KPNB1 ( NM_002265.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_002256.2 Homo sapiens karyopherin subunit beta 1 (KPNB1), transcript variant 1, mRNA.

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CloneID	OHu10409
Clone ID Related Accession (Same CDS sequence)	NM_002265.5 , NM_002265.6
Accession Version	NM_002265.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2631bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-05
Organism	Homo sapiens(human)
Product	importin subunit beta-1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB083013.1, BC036703.2, BQ009884.1, AC015674.12 and AI076614.1. On Feb 13, 2013 this sequence version replaced NM_002265.4. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: L38951.1, SRR1660805.130913.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCTGA TCACCATTCT CGAGAAGACC GTGTCTCCCG ATCGGCTGGA GCTGGAAGCG 
GCGCAGAAGT TCCTGGAGCG TGCGGCCGTG GAGAACCTGC CCACTTTCCT TGTGGAACTG 
TCCAGAGTGC TGGCAAATCC AGGAAACAGT CAGGTTGCCA GAGTTGCAGC TGGTCTACAA 
ATCAAGAACT CTTTGACATC TAAAGATCCA GATATCAAGG CACAATATCA GCAGAGGTGG 
CTTGCTATTG ATGCTAATGC TCGACGAGAA GTCAAGAACT ATGTTTTGCA GACATTGGGT 
ACAGAAACTT ACCGGCCTAG TTCTGCCTCA CAGTGTGTGG CTGGTATTGC TTGTGCAGAG 
ATCCCAGTAA ACCAGTGGCC AGAACTCATT CCTCAGCTGG TGGCCAATGT CACAAACCCC 
AACAGCACAG AGCACATGAA GGAGTCGACA TTGGAAGCCA TCGGTTATAT TTGCCAAGAT 
ATAGACCCAG AGCAGCTACA AGATAAATCC AATGAGATTC TGACTGCCAT AATCCAGGGG 
ATGAGGAAAG AAGAGCCTAG TAATAATGTG AAGCTAGCTG CTACGAATGC ACTCCTGAAC 
TCATTGGAGT TCACCAAAGC AAACTTTGAT AAAGAGTCTG AAAGGCACTT TATTATGCAG 
GTGGTCTGTG AAGCCACACA GTGTCCAGAT ACGAGGGTAC GAGTGGCTGC TTTACAGAAT 
CTGGTGAAGA TAATGTCCTT ATATTATCAG TACATGGAGA CATATATGGG TCCTGCTCTT 
TTTGCAATCA CAATCGAAGC AATGAAAAGT GACATTGATG AGGTGGCTTT ACAAGGGATA 
GAATTCTGGT CCAATGTCTG TGATGAGGAA ATGGATTTGG CCATTGAAGC TTCAGAGGCA 
GCAGAACAAG GACGGCCCCC TGAGCACACC AGCAAGTTTT ATGCGAAGGG AGCACTACAG 
TATCTGGTTC CAATCCTCAC ACAGACACTA ACTAAACAGG ACGAAAATGA TGATGACGAT 
GACTGGAACC CCTGCAAAGC AGCAGGGGTG TGCCTCATGC TTCTGGCCAC CTGCTGTGAA 
GATGACATTG TCCCACATGT CCTCCCCTTC ATTAAAGAAC ACATCAAGAA CCCAGATTGG 
CGGTACCGGG ATGCAGCAGT GATGGCTTTT GGTTGTATCT TGGAAGGACC AGAGCCCAGT 
CAGCTCAAAC CACTAGTTAT ACAGGCTATG CCCACCCTAA TAGAATTAAT GAAAGACCCC 
AGTGTAGTTG TTCGAGATAC AGCTGCATGG ACTGTAGGCA GAATTTGTGA GCTGCTTCCT 
GAAGCTGCCA TCAATGATGT CTACTTGGCT CCCCTGCTAC AGTGTCTGAT TGAGGGTCTC 
AGTGCTGAAC CCAGAGTGGC TTCAAATGTG TGCTGGGCTT TCTCCAGTCT GGCTGAAGCT 
GCTTATGAAG CTGCAGACGT TGCTGATGAT CAGGAAGAAC CAGCTACTTA CTGCTTATCT 
TCTTCATTTG AACTCATAGT TCAGAAGCTC CTAGAGACTA CAGACAGACC TGATGGACAC 
CAGAACAACC TGAGGAGTTC TGCATATGAA TCTCTGATGG AAATTGTGAA AAACAGTGCC 
AAGGATTGTT ATCCTGCTGT CCAGAAAACG ACTTTGGTCA TCATGGAACG ACTGCAACAG 
GTTCTTCAGA TGGAGTCACA TATCCAGAGC ACATCCGATA GAATCCAGTT CAATGACCTT 
CAGTCTTTAC TCTGTGCAAC TCTTCAGAAT GTTCTTCGGA AAGTGCAACA TCAAGATGCT 
TTGCAGATCT CTGATGTGGT TATGGCCTCC CTGTTAAGGA TGTTCCAAAG CACAGCTGGG 
TCTGGGGGAG TACAAGAGGA TGCCCTGATG GCAGTTAGCA CACTGGTGGA AGTGTTGGGT 
GGTGAATTCC TCAAGTACAT GGAGGCCTTT AAACCCTTCC TGGGCATTGG ATTAAAAAAT 
TATGCTGAAT ACCAGGTTTG TTTGGCAGCT GTGGGCTTAG TGGGAGACTT GTGCCGTGCC 
CTGCAATCCA ACATCATACC TTTCTGTGAC GAGGTGATGC AGCTGCTTCT GGAAAATTTG 
GGGAATGAGA ACGTCCACAG GTCTGTGAAG CCGCAGATTC TGTCAGTGTT TGGTGATATT 
GCCCTTGCTA TTGGAGGAGA GTTTAAAAAA TACTTAGAGG TTGTATTGAA TACTCTTCAG 
CAGGCCTCCC AAGCCCAGGT GGACAAGTCA GACTATGACA TGGTGGATTA TCTGAATGAG 
CTAAGGGAAA GCTGCTTGGA AGCCTATACT GGAATCGTCC AGGGATTAAA GGGGGATCAG 
GAGAACGTAC ACCCGGATGT GATGCTGGTA CAACCCAGAG TAGAATTTAT TCTGTCTTTC 
ATTGACCACA TTGCTGGAGA TGAGGATCAC ACAGATGGAG TAGTAGCTTG TGCTGCTGGA 
CTAATAGGGG ACTTATGTAC AGCATTTGGG AAGGATGTAC TGAAATTAGT AGAAGCTAGG 
CCAATGATCC ATGAATTGTT AACTGAAGGG CGGAGATCGA AGACTAACAA AGCAAAAACC 
CTTGCTACAT GGGCAACAAA AGAACTGAGG AAACTGAAGA ACCAAGCTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002256.2
CDS	408..3038
Translation	MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQIKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIACAEIPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIMQVVCEATQCPDTRVRVAALQNLVKIMSLYYQYMETYMGPALFAITIEAMKSDIDEVALQGIEFWSNVCDEEMDLAIEASEAAEQGRPPEHTSKFYAKGALQYLVPILTQTLTKQDENDDDDDWNPCKAAGVCLMLLATCCEDDIVPHVLPFIKEHIKNPDWRYRDAAVMAFGCILEGPEPSQLKPLVIQAMPTLIELMKDPSVVVRDTAAWTVGRICELLPEAAINDVYLAPLLQCLIEGLSAEPRVASNVCWAFSSLAEAAYEAADVADDQEEPATYCLSSSFELIVQKLLETTDRPDGHQNNLRSSAYESLMEIVKNSAKDCYPAVQKTTLVIMERLQQVLQMESHIQSTSDRIQFNDLQSLLCATLQNVLRKVQHQDALQISDVVMASLLRMFQSTAGSGGVQEDALMAVSTLVEVLGGEFLKYMEAFKPFLGIGLKNYAEYQVCLAAVGLVGDLCRALQSNIIPFCDEVMQLLLENLGNENVHRSVKPQILSVFGDIALAIGGEFKKYLEVVLNTLQQASQAQVDKSDYDMVDYLNELRESCLEAYTGIVQGLKGDQENVHPDVMLVQPRVEFILSFIDHIAGDEDHTDGVVACAAGLIGDLCTAFGKDVLKLVEARPMIHELLTEGRRSKTNKAKTLATWATKELRKLKNQA

Target ORF information:

RefSeq Version	NM_002265.5
Organism	Homo sapiens(human)
Definition	Homo sapiens karyopherin subunit beta 1 (KPNB1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002265.5

ORF Insert Sequence:

ATGGAGCTGA TCACCATTCT CGAGAAGACC GTGTCTCCCG ATCGGCTGGA GCTGGAAGCG 
GCGCAGAAGT TCCTGGAGCG TGCGGCCGTG GAGAACCTGC CCACTTTCCT TGTGGAACTG 
TCCAGAGTGC TGGCAAATCC AGGAAACAGT CAGGTTGCCA GAGTTGCAGC TGGTCTACAA 
ATCAAGAACT CTTTGACATC TAAAGATCCA GATATCAAGG CACAATATCA GCAGAGGTGG 
CTTGCTATTG ATGCTAATGC TCGACGAGAA GTCAAGAACT ATGTTTTGCA GACATTGGGT 
ACAGAAACTT ACCGGCCTAG TTCTGCCTCA CAGTGTGTGG CTGGTATTGC TTGTGCAGAG 
ATCCCAGTAA ACCAGTGGCC AGAACTCATT CCTCAGCTGG TGGCCAATGT CACAAACCCC 
AACAGCACAG AGCACATGAA GGAGTCGACA TTGGAAGCCA TCGGTTATAT TTGCCAAGAT 
ATAGACCCAG AGCAGCTACA AGATAAATCC AATGAGATTC TGACTGCCAT AATCCAGGGG 
ATGAGGAAAG AAGAGCCTAG TAATAATGTG AAGCTAGCTG CTACGAATGC ACTCCTGAAC 
TCATTGGAGT TCACCAAAGC AAACTTTGAT AAAGAGTCTG AAAGGCACTT TATTATGCAG 
GTGGTCTGTG AAGCCACACA GTGTCCAGAT ACGAGGGTAC GAGTGGCTGC TTTACAGAAT 
CTGGTGAAGA TAATGTCCTT ATATTATCAG TACATGGAGA CATATATGGG TCCTGCTCTT 
TTTGCAATCA CAATCGAAGC AATGAAAAGT GACATTGATG AGGTGGCTTT ACAAGGGATA 
GAATTCTGGT CCAATGTCTG TGATGAGGAA ATGGATTTGG CCATTGAAGC TTCAGAGGCA 
GCAGAACAAG GACGGCCCCC TGAGCACACC AGCAAGTTTT ATGCGAAGGG AGCACTACAG 
TATCTGGTTC CAATCCTCAC ACAGACACTA ACTAAACAGG ACGAAAATGA TGATGACGAT 
GACTGGAACC CCTGCAAAGC AGCAGGGGTG TGCCTCATGC TTCTGGCCAC CTGCTGTGAA 
GATGACATTG TCCCACATGT CCTCCCCTTC ATTAAAGAAC ACATCAAGAA CCCAGATTGG 
CGGTACCGGG ATGCAGCAGT GATGGCTTTT GGTTGTATCT TGGAAGGACC AGAGCCCAGT 
CAGCTCAAAC CACTAGTTAT ACAGGCTATG CCCACCCTAA TAGAATTAAT GAAAGACCCC 
AGTGTAGTTG TTCGAGATAC AGCTGCATGG ACTGTAGGCA GAATTTGTGA GCTGCTTCCT 
GAAGCTGCCA TCAATGATGT CTACTTGGCT CCCCTGCTAC AGTGTCTGAT TGAGGGTCTC 
AGTGCTGAAC CCAGAGTGGC TTCAAATGTG TGCTGGGCTT TCTCCAGTCT GGCTGAAGCT 
GCTTATGAAG CTGCAGACGT TGCTGATGAT CAGGAAGAAC CAGCTACTTA CTGCTTATCT 
TCTTCATTTG AACTCATAGT TCAGAAGCTC CTAGAGACTA CAGACAGACC TGATGGACAC 
CAGAACAACC TGAGGAGTTC TGCATATGAA TCTCTGATGG AAATTGTGAA AAACAGTGCC 
AAGGATTGTT ATCCTGCTGT CCAGAAAACG ACTTTGGTCA TCATGGAACG ACTGCAACAG 
GTTCTTCAGA TGGAGTCACA TATCCAGAGC ACATCCGATA GAATCCAGTT CAATGACCTT 
CAGTCTTTAC TCTGTGCAAC TCTTCAGAAT GTTCTTCGGA AAGTGCAACA TCAAGATGCT 
TTGCAGATCT CTGATGTGGT TATGGCCTCC CTGTTAAGGA TGTTCCAAAG CACAGCTGGG 
TCTGGGGGAG TACAAGAGGA TGCCCTGATG GCAGTTAGCA CACTGGTGGA AGTGTTGGGT 
GGTGAATTCC TCAAGTACAT GGAGGCCTTT AAACCCTTCC TGGGCATTGG ATTAAAAAAT 
TATGCTGAAT ACCAGGTTTG TTTGGCAGCT GTGGGCTTAG TGGGAGACTT GTGCCGTGCC 
CTGCAATCCA ACATCATACC TTTCTGTGAC GAGGTGATGC AGCTGCTTCT GGAAAATTTG 
GGGAATGAGA ACGTCCACAG GTCTGTGAAG CCGCAGATTC TGTCAGTGTT TGGTGATATT 
GCCCTTGCTA TTGGAGGAGA GTTTAAAAAA TACTTAGAGG TTGTATTGAA TACTCTTCAG 
CAGGCCTCCC AAGCCCAGGT GGACAAGTCA GACTATGACA TGGTGGATTA TCTGAATGAG 
CTAAGGGAAA GCTGCTTGGA AGCCTATACT GGAATCGTCC AGGGATTAAA GGGGGATCAG 
GAGAACGTAC ACCCGGATGT GATGCTGGTA CAACCCAGAG TAGAATTTAT TCTGTCTTTC 
ATTGACCACA TTGCTGGAGA TGAGGATCAC ACAGATGGAG TAGTAGCTTG TGCTGCTGGA 
CTAATAGGGG ACTTATGTAC AGCATTTGGG AAGGATGTAC TGAAATTAGT AGAAGCTAGG 
CCAATGATCC ATGAATTGTT AACTGAAGGG CGGAGATCGA AGACTAACAA AGCAAAAACC 
CTTGCTACAT GGGCAACAAA AGAACTGAGG AAACTGAAGA ACCAAGCTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KPNB1 ( NM_002265.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_002256.2 Homo sapiens karyopherin subunit beta 1 (KPNB1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu10409
Clone ID Related Accession (Same CDS sequence)	NM_002265.5 , NM_002265.6
Accession Version	NM_002265.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2631bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Homo sapiens(human)
Product	importin subunit beta-1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC025682.6, AC015674.12 and KF570270.1. On Nov 22, 2018 this sequence version replaced NM_002265.5. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: L38951.1, SRR1660805.130913.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000290158.9/ ENSP00000290158.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGCTGA TCACCATTCT CGAGAAGACC GTGTCTCCCG ATCGGCTGGA GCTGGAAGCG 
GCGCAGAAGT TCCTGGAGCG TGCGGCCGTG GAGAACCTGC CCACTTTCCT TGTGGAACTG 
TCCAGAGTGC TGGCAAATCC AGGAAACAGT CAGGTTGCCA GAGTTGCAGC TGGTCTACAA 
ATCAAGAACT CTTTGACATC TAAAGATCCA GATATCAAGG CACAATATCA GCAGAGGTGG 
CTTGCTATTG ATGCTAATGC TCGACGAGAA GTCAAGAACT ATGTTTTGCA GACATTGGGT 
ACAGAAACTT ACCGGCCTAG TTCTGCCTCA CAGTGTGTGG CTGGTATTGC TTGTGCAGAG 
ATCCCAGTAA ACCAGTGGCC AGAACTCATT CCTCAGCTGG TGGCCAATGT CACAAACCCC 
AACAGCACAG AGCACATGAA GGAGTCGACA TTGGAAGCCA TCGGTTATAT TTGCCAAGAT 
ATAGACCCAG AGCAGCTACA AGATAAATCC AATGAGATTC TGACTGCCAT AATCCAGGGG 
ATGAGGAAAG AAGAGCCTAG TAATAATGTG AAGCTAGCTG CTACGAATGC ACTCCTGAAC 
TCATTGGAGT TCACCAAAGC AAACTTTGAT AAAGAGTCTG AAAGGCACTT TATTATGCAG 
GTGGTCTGTG AAGCCACACA GTGTCCAGAT ACGAGGGTAC GAGTGGCTGC TTTACAGAAT 
CTGGTGAAGA TAATGTCCTT ATATTATCAG TACATGGAGA CATATATGGG TCCTGCTCTT 
TTTGCAATCA CAATCGAAGC AATGAAAAGT GACATTGATG AGGTGGCTTT ACAAGGGATA 
GAATTCTGGT CCAATGTCTG TGATGAGGAA ATGGATTTGG CCATTGAAGC TTCAGAGGCA 
GCAGAACAAG GACGGCCCCC TGAGCACACC AGCAAGTTTT ATGCGAAGGG AGCACTACAG 
TATCTGGTTC CAATCCTCAC ACAGACACTA ACTAAACAGG ACGAAAATGA TGATGACGAT 
GACTGGAACC CCTGCAAAGC AGCAGGGGTG TGCCTCATGC TTCTGGCCAC CTGCTGTGAA 
GATGACATTG TCCCACATGT CCTCCCCTTC ATTAAAGAAC ACATCAAGAA CCCAGATTGG 
CGGTACCGGG ATGCAGCAGT GATGGCTTTT GGTTGTATCT TGGAAGGACC AGAGCCCAGT 
CAGCTCAAAC CACTAGTTAT ACAGGCTATG CCCACCCTAA TAGAATTAAT GAAAGACCCC 
AGTGTAGTTG TTCGAGATAC AGCTGCATGG ACTGTAGGCA GAATTTGTGA GCTGCTTCCT 
GAAGCTGCCA TCAATGATGT CTACTTGGCT CCCCTGCTAC AGTGTCTGAT TGAGGGTCTC 
AGTGCTGAAC CCAGAGTGGC TTCAAATGTG TGCTGGGCTT TCTCCAGTCT GGCTGAAGCT 
GCTTATGAAG CTGCAGACGT TGCTGATGAT CAGGAAGAAC CAGCTACTTA CTGCTTATCT 
TCTTCATTTG AACTCATAGT TCAGAAGCTC CTAGAGACTA CAGACAGACC TGATGGACAC 
CAGAACAACC TGAGGAGTTC TGCATATGAA TCTCTGATGG AAATTGTGAA AAACAGTGCC 
AAGGATTGTT ATCCTGCTGT CCAGAAAACG ACTTTGGTCA TCATGGAACG ACTGCAACAG 
GTTCTTCAGA TGGAGTCACA TATCCAGAGC ACATCCGATA GAATCCAGTT CAATGACCTT 
CAGTCTTTAC TCTGTGCAAC TCTTCAGAAT GTTCTTCGGA AAGTGCAACA TCAAGATGCT 
TTGCAGATCT CTGATGTGGT TATGGCCTCC CTGTTAAGGA TGTTCCAAAG CACAGCTGGG 
TCTGGGGGAG TACAAGAGGA TGCCCTGATG GCAGTTAGCA CACTGGTGGA AGTGTTGGGT 
GGTGAATTCC TCAAGTACAT GGAGGCCTTT AAACCCTTCC TGGGCATTGG ATTAAAAAAT 
TATGCTGAAT ACCAGGTTTG TTTGGCAGCT GTGGGCTTAG TGGGAGACTT GTGCCGTGCC 
CTGCAATCCA ACATCATACC TTTCTGTGAC GAGGTGATGC AGCTGCTTCT GGAAAATTTG 
GGGAATGAGA ACGTCCACAG GTCTGTGAAG CCGCAGATTC TGTCAGTGTT TGGTGATATT 
GCCCTTGCTA TTGGAGGAGA GTTTAAAAAA TACTTAGAGG TTGTATTGAA TACTCTTCAG 
CAGGCCTCCC AAGCCCAGGT GGACAAGTCA GACTATGACA TGGTGGATTA TCTGAATGAG 
CTAAGGGAAA GCTGCTTGGA AGCCTATACT GGAATCGTCC AGGGATTAAA GGGGGATCAG 
GAGAACGTAC ACCCGGATGT GATGCTGGTA CAACCCAGAG TAGAATTTAT TCTGTCTTTC 
ATTGACCACA TTGCTGGAGA TGAGGATCAC ACAGATGGAG TAGTAGCTTG TGCTGCTGGA 
CTAATAGGGG ACTTATGTAC AGCATTTGGG AAGGATGTAC TGAAATTAGT AGAAGCTAGG 
CCAATGATCC ATGAATTGTT AACTGAAGGG CGGAGATCGA AGACTAACAA AGCAAAAACC 
CTTGCTACAT GGGCAACAAA AGAACTGAGG AAACTGAAGA ACCAAGCTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002256.2
CDS	327..2957
Translation	MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQIKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIACAEIPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIMQVVCEATQCPDTRVRVAALQNLVKIMSLYYQYMETYMGPALFAITIEAMKSDIDEVALQGIEFWSNVCDEEMDLAIEASEAAEQGRPPEHTSKFYAKGALQYLVPILTQTLTKQDENDDDDDWNPCKAAGVCLMLLATCCEDDIVPHVLPFIKEHIKNPDWRYRDAAVMAFGCILEGPEPSQLKPLVIQAMPTLIELMKDPSVVVRDTAAWTVGRICELLPEAAINDVYLAPLLQCLIEGLSAEPRVASNVCWAFSSLAEAAYEAADVADDQEEPATYCLSSSFELIVQKLLETTDRPDGHQNNLRSSAYESLMEIVKNSAKDCYPAVQKTTLVIMERLQQVLQMESHIQSTSDRIQFNDLQSLLCATLQNVLRKVQHQDALQISDVVMASLLRMFQSTAGSGGVQEDALMAVSTLVEVLGGEFLKYMEAFKPFLGIGLKNYAEYQVCLAAVGLVGDLCRALQSNIIPFCDEVMQLLLENLGNENVHRSVKPQILSVFGDIALAIGGEFKKYLEVVLNTLQQASQAQVDKSDYDMVDYLNELRESCLEAYTGIVQGLKGDQENVHPDVMLVQPRVEFILSFIDHIAGDEDHTDGVVACAAGLIGDLCTAFGKDVLKLVEARPMIHELLTEGRRSKTNKAKTLATWATKELRKLKNQA

Target ORF information:

RefSeq Version	NM_002265.6
Organism	Homo sapiens(human)
Definition	Homo sapiens karyopherin subunit beta 1 (KPNB1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002265.6

ORF Insert Sequence:

ATGGAGCTGA TCACCATTCT CGAGAAGACC GTGTCTCCCG ATCGGCTGGA GCTGGAAGCG 
GCGCAGAAGT TCCTGGAGCG TGCGGCCGTG GAGAACCTGC CCACTTTCCT TGTGGAACTG 
TCCAGAGTGC TGGCAAATCC AGGAAACAGT CAGGTTGCCA GAGTTGCAGC TGGTCTACAA 
ATCAAGAACT CTTTGACATC TAAAGATCCA GATATCAAGG CACAATATCA GCAGAGGTGG 
CTTGCTATTG ATGCTAATGC TCGACGAGAA GTCAAGAACT ATGTTTTGCA GACATTGGGT 
ACAGAAACTT ACCGGCCTAG TTCTGCCTCA CAGTGTGTGG CTGGTATTGC TTGTGCAGAG 
ATCCCAGTAA ACCAGTGGCC AGAACTCATT CCTCAGCTGG TGGCCAATGT CACAAACCCC 
AACAGCACAG AGCACATGAA GGAGTCGACA TTGGAAGCCA TCGGTTATAT TTGCCAAGAT 
ATAGACCCAG AGCAGCTACA AGATAAATCC AATGAGATTC TGACTGCCAT AATCCAGGGG 
ATGAGGAAAG AAGAGCCTAG TAATAATGTG AAGCTAGCTG CTACGAATGC ACTCCTGAAC 
TCATTGGAGT TCACCAAAGC AAACTTTGAT AAAGAGTCTG AAAGGCACTT TATTATGCAG 
GTGGTCTGTG AAGCCACACA GTGTCCAGAT ACGAGGGTAC GAGTGGCTGC TTTACAGAAT 
CTGGTGAAGA TAATGTCCTT ATATTATCAG TACATGGAGA CATATATGGG TCCTGCTCTT 
TTTGCAATCA CAATCGAAGC AATGAAAAGT GACATTGATG AGGTGGCTTT ACAAGGGATA 
GAATTCTGGT CCAATGTCTG TGATGAGGAA ATGGATTTGG CCATTGAAGC TTCAGAGGCA 
GCAGAACAAG GACGGCCCCC TGAGCACACC AGCAAGTTTT ATGCGAAGGG AGCACTACAG 
TATCTGGTTC CAATCCTCAC ACAGACACTA ACTAAACAGG ACGAAAATGA TGATGACGAT 
GACTGGAACC CCTGCAAAGC AGCAGGGGTG TGCCTCATGC TTCTGGCCAC CTGCTGTGAA 
GATGACATTG TCCCACATGT CCTCCCCTTC ATTAAAGAAC ACATCAAGAA CCCAGATTGG 
CGGTACCGGG ATGCAGCAGT GATGGCTTTT GGTTGTATCT TGGAAGGACC AGAGCCCAGT 
CAGCTCAAAC CACTAGTTAT ACAGGCTATG CCCACCCTAA TAGAATTAAT GAAAGACCCC 
AGTGTAGTTG TTCGAGATAC AGCTGCATGG ACTGTAGGCA GAATTTGTGA GCTGCTTCCT 
GAAGCTGCCA TCAATGATGT CTACTTGGCT CCCCTGCTAC AGTGTCTGAT TGAGGGTCTC 
AGTGCTGAAC CCAGAGTGGC TTCAAATGTG TGCTGGGCTT TCTCCAGTCT GGCTGAAGCT 
GCTTATGAAG CTGCAGACGT TGCTGATGAT CAGGAAGAAC CAGCTACTTA CTGCTTATCT 
TCTTCATTTG AACTCATAGT TCAGAAGCTC CTAGAGACTA CAGACAGACC TGATGGACAC 
CAGAACAACC TGAGGAGTTC TGCATATGAA TCTCTGATGG AAATTGTGAA AAACAGTGCC 
AAGGATTGTT ATCCTGCTGT CCAGAAAACG ACTTTGGTCA TCATGGAACG ACTGCAACAG 
GTTCTTCAGA TGGAGTCACA TATCCAGAGC ACATCCGATA GAATCCAGTT CAATGACCTT 
CAGTCTTTAC TCTGTGCAAC TCTTCAGAAT GTTCTTCGGA AAGTGCAACA TCAAGATGCT 
TTGCAGATCT CTGATGTGGT TATGGCCTCC CTGTTAAGGA TGTTCCAAAG CACAGCTGGG 
TCTGGGGGAG TACAAGAGGA TGCCCTGATG GCAGTTAGCA CACTGGTGGA AGTGTTGGGT 
GGTGAATTCC TCAAGTACAT GGAGGCCTTT AAACCCTTCC TGGGCATTGG ATTAAAAAAT 
TATGCTGAAT ACCAGGTTTG TTTGGCAGCT GTGGGCTTAG TGGGAGACTT GTGCCGTGCC 
CTGCAATCCA ACATCATACC TTTCTGTGAC GAGGTGATGC AGCTGCTTCT GGAAAATTTG 
GGGAATGAGA ACGTCCACAG GTCTGTGAAG CCGCAGATTC TGTCAGTGTT TGGTGATATT 
GCCCTTGCTA TTGGAGGAGA GTTTAAAAAA TACTTAGAGG TTGTATTGAA TACTCTTCAG 
CAGGCCTCCC AAGCCCAGGT GGACAAGTCA GACTATGACA TGGTGGATTA TCTGAATGAG 
CTAAGGGAAA GCTGCTTGGA AGCCTATACT GGAATCGTCC AGGGATTAAA GGGGGATCAG 
GAGAACGTAC ACCCGGATGT GATGCTGGTA CAACCCAGAG TAGAATTTAT TCTGTCTTTC 
ATTGACCACA TTGCTGGAGA TGAGGATCAC ACAGATGGAG TAGTAGCTTG TGCTGCTGGA 
CTAATAGGGG ACTTATGTAC AGCATTTGGG AAGGATGTAC TGAAATTAGT AGAAGCTAGG 
CCAATGATCC ATGAATTGTT AACTGAAGGG CGGAGATCGA AGACTAACAA AGCAAAAACC 
CTTGCTACAT GGGCAACAAA AGAACTGAGG AAACTGAAGA ACCAAGCTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

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KPNB1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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