KIR2DL2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	KIR2DL2
Entrez Gene ID	3803
Full Name	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2
Synonyms	CD158B1,CD158b,NKAT-6,NKAT6,p58.2
General protein information	Preferred Names killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2 Names killer cell immunoglobulin-like receptor 2DL2 CD158 antigen-like family member B1 MHC class I NK cell receptor killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2 natural killer-associated transcript 6 p58 NK receptor CL-43 p58 natural killer cell receptor clone CL-43
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.4
Summary	Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq, Jul 2008].
Disorder MIM:	604937

mRNA and Protein(s)

mRNA	Protein	Name
XM_017030246.1	XP_016885735.1	killer cell immunoglobulin-like receptor 2DL2 isoform X2
XM_017030270.1	XP_016885759.1	killer cell immunoglobulin-like receptor 2DL2 isoform X4
XM_017030245.1	XP_016885734.1	killer cell immunoglobulin-like receptor 2DL2 isoform X1
XM_017030269.1	XP_016885758.1	killer cell immunoglobulin-like receptor 2DL2 isoform X3
NM_014219.2	NP_055034.2	killer cell immunoglobulin-like receptor 2DL2 precursor

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

HIV-1 Control by NK Cells via Reduced Interaction between KIR2DL2 and HLA-C
Lin Z, Kuroki K, Kuse N, Sun X, Akahoshi T, Qi Y, Chikata T, Naruto T, Koyanagi M, Murakoshi H, Gatanaga H, Oka S, Carrington M, Maenaka K, Takiguchi M
Cell reports17(9)2210-2220(2016 11)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

KIR2DL2/HLA-C( *)12:02 and KIR2DL2/HLA-C( *)14:03 compound genotypes have protective effects on control of HIV-1.
Title: HIV-1 Control by NK Cells via Reduced Interaction between KIR2DL2 and HLA-C

association between KIR2DS2 and the response to methotrexate (MTX), moreover, the combination KIR2DL2+/KIR2DS2+ was more frequent in responders to MTX (p = 0.043).
Title: KIR2DL2 and KIR2DS2 as genetic markers to the methotrexate response in rheumatoid arthritis patients.

KIR2DL2 gene polymorphism is associated with HIV-1 infection.
Title: The effects of killer cell immunoglobulin-like receptor (KIR) genes on susceptibility to HIV-1 infection in the Polish population.

KIR2DL2/KIR2DL3-glutamate(35) alleles are functionally stronger than -glutamine(35) alleles.
Title: KIR2DL2/2DL3-E(35) alleles are functionally stronger than -Q(35) alleles.

KIR2DL2/2DS2-C1C1 genotype is associated with type 1 diabetes in Saudi children
Title: Investigation of activating and inhibitory killer cell immunoglobulin-like receptors and their putative ligands in type 1 diabetes (T1D).

The following KIR2DL2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KIR2DL2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu17046	NM_014219.2 Latest version!	Homo sapiens killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2 (KIR2DL2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$144.50-$202.30 $289.00
OHu17046	XM_017030269.1 Latest version!	Homo sapiens killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2 (KIR2DL2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$144.50-$202.30 $289.00
OHu17046	XM_017030245.1 Latest version!	Homo sapiens killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2 (KIR2DL2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$144.50-$202.30 $289.00
OHu100093	XM_017030270.1 Latest version!	Homo sapiens killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2 (KIR2DL2), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu100093	XM_017030246.1 Latest version!	Homo sapiens killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2 (KIR2DL2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KIR2DL2 ( NM_014219.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_055034.2 Homo sapiens killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2 (KIR2DL2), mRNA.

Price & Availability↑

CloneID	OHu17046
Clone ID Related Accession (Same CDS sequence)	XM_017030245.1 , XM_017030269.1 , NM_014219.2
Accession Version	NM_014219.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1047bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Homo sapiens(human)
Product	killer cell immunoglobulin-like receptor 2DL2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY366242.1, AF285434.1 and U24075.1. On or before Mar 22, 2015 this sequence version replaced XM_011547159.1, XM_011547550.1, XM_005272924.1, XM_003403575.1, XM_003403576.1, NM_014219.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U24075.1, AF285439.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGTCGCTCA TGGTCGTCAG CATGGCGTGT GTTGGGTTCT TCTTGCTGCA GGGGGCCTGG 
CCACATGAGG GAGTCCACAG AAAACCTTCC CTCCTGGCCC ACCCAGGTCG CCTGGTGAAA 
TCAGAAGAGA CAGTCATCCT GCAATGTTGG TCAGATGTCA GGTTTGAGCA CTTCCTTCTG 
CACAGAGAAG GGAAGTTTAA GGACACTTTG CACCTCATTG GAGAGCACCA TGATGGGGTC 
TCCAAAGCCA ACTTCTCCAT CGGTCCCATG ATGCAAGACC TTGCAGGGAC CTACAGATGC 
TACGGTTCTG TTACTCACTC CCCCTATCAG TTGTCAGCTC CCAGTGACCC TCTGGACATC 
GTCATCACAG GTCTATATGA GAAACCTTCT CTCTCAGCCC AGCCGGGCCC CACGGTTCTG 
GCAGGAGAGA GCGTGACCTT GTCCTGCAGC TCCCGGAGCT CCTATGACAT GTACCATCTA 
TCCAGGGAGG GGGAGGCCCA TGAATGTAGG TTCTCTGCAG GGCCCAAGGT CAACGGAACA 
TTCCAGGCCG ACTTTCCTCT GGGCCCTGCC ACCCACGGAG GAACCTACAG ATGCTTCGGC 
TCTTTCCGTG ACTCTCCATA CGAGTGGTCA AACTCGAGTG ACCCACTGCT TGTTTCTGTC 
ACAGGAAACC CTTCAAATAG TTGGCCTTCA CCCACTGAAC CAAGCTCTAA AACCGGTAAC 
CCCCGACACC TGCACATTCT GATTGGGACC TCAGTGGTCA TCATCCTCTT CATCCTCCTC 
TTCTTTCTCC TTCATCGCTG GTGCTCCAAC AAAAAAAATG CTGCGGTAAT GGACCAAGAG 
TCTGCAGGGA ACAGAACAGC GAATAGCGAG GACTCTGATG AACAAGACCC TCAGGAGGTG 
ACATACACAC AGTTGAATCA CTGCGTTTTC ACACAGAGAA AAATCACTCG CCCTTCTCAG 
AGGCCCAAGA CACCCCCAAC AGATATCATC GTGTACACGG AACTTCCAAA TGCTGAGTCC 
AGATCCAAAG TTGTCTCCTG CCCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055034.2
CDS	30..1076
Translation	MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLLHREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGTFQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGNPRHLHILIGTSVVIILFILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKVVSCP

Target ORF information:

RefSeq Version	NM_014219.2
Organism	Homo sapiens(human)
Definition	Homo sapiens killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2 (KIR2DL2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014219.2

ORF Insert Sequence:

ATGTCGCTCA TGGTCGTCAG CATGGCGTGT GTTGGGTTCT TCTTGCTGCA GGGGGCCTGG 
CCACATGAGG GAGTCCACAG AAAACCTTCC CTCCTGGCCC ACCCAGGTCG CCTGGTGAAA 
TCAGAAGAGA CAGTCATCCT GCAATGTTGG TCAGATGTCA GGTTTGAGCA CTTCCTTCTG 
CACAGAGAAG GGAAGTTTAA GGACACTTTG CACCTCATTG GAGAGCACCA TGATGGGGTC 
TCCAAAGCCA ACTTCTCCAT CGGTCCCATG ATGCAAGACC TTGCAGGGAC CTACAGATGC 
TACGGTTCTG TTACTCACTC CCCCTATCAG TTGTCAGCTC CCAGTGACCC TCTGGACATC 
GTCATCACAG GTCTATATGA GAAACCTTCT CTCTCAGCCC AGCCGGGCCC CACGGTTCTG 
GCAGGAGAGA GCGTGACCTT GTCCTGCAGC TCCCGGAGCT CCTATGACAT GTACCATCTA 
TCCAGGGAGG GGGAGGCCCA TGAATGTAGG TTCTCTGCAG GGCCCAAGGT CAACGGAACA 
TTCCAGGCCG ACTTTCCTCT GGGCCCTGCC ACCCACGGAG GAACCTACAG ATGCTTCGGC 
TCTTTCCGTG ACTCTCCATA CGAGTGGTCA AACTCGAGTG ACCCACTGCT TGTTTCTGTC 
ACAGGAAACC CTTCAAATAG TTGGCCTTCA CCCACTGAAC CAAGCTCTAA AACCGGTAAC 
CCCCGACACC TGCACATTCT GATTGGGACC TCAGTGGTCA TCATCCTCTT CATCCTCCTC 
TTCTTTCTCC TTCATCGCTG GTGCTCCAAC AAAAAAAATG CTGCGGTAAT GGACCAAGAG 
TCTGCAGGGA ACAGAACAGC GAATAGCGAG GACTCTGATG AACAAGACCC TCAGGAGGTG 
ACATACACAC AGTTGAATCA CTGCGTTTTC ACACAGAGAA AAATCACTCG CCCTTCTCAG 
AGGCCCAAGA CACCCCCAAC AGATATCATC GTGTACACGG AACTTCCAAA TGCTGAGTCC 
AGATCCAAAG TTGTCTCCTG CCCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KIR2DL2 ( XM_017030245.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016885734.1 Homo sapiens killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2 (KIR2DL2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu17046
Clone ID Related Accession (Same CDS sequence)	XM_017030245.1 , XM_017030269.1 , NM_014219.2
Accession Version	XM_017030245.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1047bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	killer cell immunoglobulin-like receptor 2DL2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_187644.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCGCTCA TGGTCGTCAG CATGGCGTGT GTTGGGTTCT TCTTGCTGCA GGGGGCCTGG 
CCACATGAGG GAGTCCACAG AAAACCTTCC CTCCTGGCCC ACCCAGGTCG CCTGGTGAAA 
TCAGAAGAGA CAGTCATCCT GCAATGTTGG TCAGATGTCA GGTTTGAGCA CTTCCTTCTG 
CACAGAGAAG GGAAGTTTAA GGACACTTTG CACCTCATTG GAGAGCACCA TGATGGGGTC 
TCCAAAGCCA ACTTCTCCAT CGGTCCCATG ATGCAAGACC TTGCAGGGAC CTACAGATGC 
TACGGTTCTG TTACTCACTC CCCCTATCAG TTGTCAGCTC CCAGTGACCC TCTGGACATC 
GTCATCACAG GTCTATATGA GAAACCTTCT CTCTCAGCCC AGCCGGGCCC CACGGTTCTG 
GCAGGAGAGA GCGTGACCTT GTCCTGCAGC TCCCGGAGCT CCTATGACAT GTACCATCTA 
TCCAGGGAGG GGGAGGCCCA TGAATGTAGG TTCTCTGCAG GGCCCAAGGT CAACGGAACA 
TTCCAGGCCG ACTTTCCTCT GGGCCCTGCC ACCCACGGAG GAACCTACAG ATGCTTCGGC 
TCTTTCCGTG ACTCTCCATA CGAGTGGTCA AACTCGAGTG ACCCACTGCT TGTTTCTGTC 
ACAGGAAACC CTTCAAATAG TTGGCCTTCA CCCACTGAAC CAAGCTCTAA AACCGGTAAC 
CCCCGACACC TGCACATTCT GATTGGGACC TCAGTGGTCA TCATCCTCTT CATCCTCCTC 
TTCTTTCTCC TTCATCGCTG GTGCTCCAAC AAAAAAAATG CTGCGGTAAT GGACCAAGAG 
TCTGCAGGGA ACAGAACAGC GAATAGCGAG GACTCTGATG AACAAGACCC TCAGGAGGTG 
ACATACACAC AGTTGAATCA CTGCGTTTTC ACACAGAGAA AAATCACTCG CCCTTCTCAG 
AGGCCCAAGA CACCCCCAAC AGATATCATC GTGTACACGG AACTTCCAAA TGCTGAGTCC 
AGATCCAAAG TTGTCTCCTG CCCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016885734.1
CDS	157..1203
Translation	MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLLHREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGTFQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGNPRHLHILIGTSVVIILFILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKVVSCP

Target ORF information:

RefSeq Version	XM_017030245.1
Organism	Homo sapiens(human)
Definition	Homo sapiens killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2 (KIR2DL2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017030245.1

ORF Insert Sequence:

ATGTCGCTCA TGGTCGTCAG CATGGCGTGT GTTGGGTTCT TCTTGCTGCA GGGGGCCTGG 
CCACATGAGG GAGTCCACAG AAAACCTTCC CTCCTGGCCC ACCCAGGTCG CCTGGTGAAA 
TCAGAAGAGA CAGTCATCCT GCAATGTTGG TCAGATGTCA GGTTTGAGCA CTTCCTTCTG 
CACAGAGAAG GGAAGTTTAA GGACACTTTG CACCTCATTG GAGAGCACCA TGATGGGGTC 
TCCAAAGCCA ACTTCTCCAT CGGTCCCATG ATGCAAGACC TTGCAGGGAC CTACAGATGC 
TACGGTTCTG TTACTCACTC CCCCTATCAG TTGTCAGCTC CCAGTGACCC TCTGGACATC 
GTCATCACAG GTCTATATGA GAAACCTTCT CTCTCAGCCC AGCCGGGCCC CACGGTTCTG 
GCAGGAGAGA GCGTGACCTT GTCCTGCAGC TCCCGGAGCT CCTATGACAT GTACCATCTA 
TCCAGGGAGG GGGAGGCCCA TGAATGTAGG TTCTCTGCAG GGCCCAAGGT CAACGGAACA 
TTCCAGGCCG ACTTTCCTCT GGGCCCTGCC ACCCACGGAG GAACCTACAG ATGCTTCGGC 
TCTTTCCGTG ACTCTCCATA CGAGTGGTCA AACTCGAGTG ACCCACTGCT TGTTTCTGTC 
ACAGGAAACC CTTCAAATAG TTGGCCTTCA CCCACTGAAC CAAGCTCTAA AACCGGTAAC 
CCCCGACACC TGCACATTCT GATTGGGACC TCAGTGGTCA TCATCCTCTT CATCCTCCTC 
TTCTTTCTCC TTCATCGCTG GTGCTCCAAC AAAAAAAATG CTGCGGTAAT GGACCAAGAG 
TCTGCAGGGA ACAGAACAGC GAATAGCGAG GACTCTGATG AACAAGACCC TCAGGAGGTG 
ACATACACAC AGTTGAATCA CTGCGTTTTC ACACAGAGAA AAATCACTCG CCCTTCTCAG 
AGGCCCAAGA CACCCCCAAC AGATATCATC GTGTACACGG AACTTCCAAA TGCTGAGTCC 
AGATCCAAAG TTGTCTCCTG CCCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KIR2DL2 ( XM_017030269.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016885758.1 Homo sapiens killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2 (KIR2DL2), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu17046
Clone ID Related Accession (Same CDS sequence)	XM_017030245.1 , XM_017030269.1 , NM_014219.2
Accession Version	XM_017030269.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1047bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	killer cell immunoglobulin-like receptor 2DL2 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_187670.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCGCTCA TGGTCGTCAG CATGGCGTGT GTTGGGTTCT TCTTGCTGCA GGGGGCCTGG 
CCACATGAGG GAGTCCACAG AAAACCTTCC CTCCTGGCCC ACCCAGGTCG CCTGGTGAAA 
TCAGAAGAGA CAGTCATCCT GCAATGTTGG TCAGATGTCA GGTTTGAGCA CTTCCTTCTG 
CACAGAGAAG GGAAGTTTAA GGACACTTTG CACCTCATTG GAGAGCACCA TGATGGGGTC 
TCCAAAGCCA ACTTCTCCAT CGGTCCCATG ATGCAAGACC TTGCAGGGAC CTACAGATGC 
TACGGTTCTG TTACTCACTC CCCCTATCAG TTGTCAGCTC CCAGTGACCC TCTGGACATC 
GTCATCACAG GTCTATATGA GAAACCTTCT CTCTCAGCCC AGCCGGGCCC CACGGTTCTG 
GCAGGAGAGA GCGTGACCTT GTCCTGCAGC TCCCGGAGCT CCTATGACAT GTACCATCTA 
TCCAGGGAGG GGGAGGCCCA TGAATGTAGG TTCTCTGCAG GGCCCAAGGT CAACGGAACA 
TTCCAGGCCG ACTTTCCTCT GGGCCCTGCC ACCCACGGAG GAACCTACAG ATGCTTCGGC 
TCTTTCCGTG ACTCTCCATA CGAGTGGTCA AACTCGAGTG ACCCACTGCT TGTTTCTGTC 
ACAGGAAACC CTTCAAATAG TTGGCCTTCA CCCACTGAAC CAAGCTCTAA AACCGGTAAC 
CCCCGACACC TGCACATTCT GATTGGGACC TCAGTGGTCA TCATCCTCTT CATCCTCCTC 
TTCTTTCTCC TTCATCGCTG GTGCTCCAAC AAAAAAAATG CTGCGGTAAT GGACCAAGAG 
TCTGCAGGGA ACAGAACAGC GAATAGCGAG GACTCTGATG AACAAGACCC TCAGGAGGTG 
ACATACACAC AGTTGAATCA CTGCGTTTTC ACACAGAGAA AAATCACTCG CCCTTCTCAG 
AGGCCCAAGA CACCCCCAAC AGATATCATC GTGTACACGG AACTTCCAAA TGCTGAGTCC 
AGATCCAAAG TTGTCTCCTG CCCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016885758.1
CDS	157..1203
Translation	MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLLHREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGTFQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGNPRHLHILIGTSVVIILFILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKVVSCP

Target ORF information:

RefSeq Version	XM_017030269.1
Organism	Homo sapiens(human)
Definition	Homo sapiens killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2 (KIR2DL2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017030269.1

ORF Insert Sequence:

ATGTCGCTCA TGGTCGTCAG CATGGCGTGT GTTGGGTTCT TCTTGCTGCA GGGGGCCTGG 
CCACATGAGG GAGTCCACAG AAAACCTTCC CTCCTGGCCC ACCCAGGTCG CCTGGTGAAA 
TCAGAAGAGA CAGTCATCCT GCAATGTTGG TCAGATGTCA GGTTTGAGCA CTTCCTTCTG 
CACAGAGAAG GGAAGTTTAA GGACACTTTG CACCTCATTG GAGAGCACCA TGATGGGGTC 
TCCAAAGCCA ACTTCTCCAT CGGTCCCATG ATGCAAGACC TTGCAGGGAC CTACAGATGC 
TACGGTTCTG TTACTCACTC CCCCTATCAG TTGTCAGCTC CCAGTGACCC TCTGGACATC 
GTCATCACAG GTCTATATGA GAAACCTTCT CTCTCAGCCC AGCCGGGCCC CACGGTTCTG 
GCAGGAGAGA GCGTGACCTT GTCCTGCAGC TCCCGGAGCT CCTATGACAT GTACCATCTA 
TCCAGGGAGG GGGAGGCCCA TGAATGTAGG TTCTCTGCAG GGCCCAAGGT CAACGGAACA 
TTCCAGGCCG ACTTTCCTCT GGGCCCTGCC ACCCACGGAG GAACCTACAG ATGCTTCGGC 
TCTTTCCGTG ACTCTCCATA CGAGTGGTCA AACTCGAGTG ACCCACTGCT TGTTTCTGTC 
ACAGGAAACC CTTCAAATAG TTGGCCTTCA CCCACTGAAC CAAGCTCTAA AACCGGTAAC 
CCCCGACACC TGCACATTCT GATTGGGACC TCAGTGGTCA TCATCCTCTT CATCCTCCTC 
TTCTTTCTCC TTCATCGCTG GTGCTCCAAC AAAAAAAATG CTGCGGTAAT GGACCAAGAG 
TCTGCAGGGA ACAGAACAGC GAATAGCGAG GACTCTGATG AACAAGACCC TCAGGAGGTG 
ACATACACAC AGTTGAATCA CTGCGTTTTC ACACAGAGAA AAATCACTCG CCCTTCTCAG 
AGGCCCAAGA CACCCCCAAC AGATATCATC GTGTACACGG AACTTCCAAA TGCTGAGTCC 
AGATCCAAAG TTGTCTCCTG CCCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KIR2DL2 ( XM_017030246.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016885735.1 Homo sapiens killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2 (KIR2DL2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu100093
Clone ID Related Accession (Same CDS sequence)	XM_017030246.1 , XM_017030270.1
Accession Version	XM_017030246.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1125bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	killer cell immunoglobulin-like receptor 2DL2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_187644.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCGCTCA TGGTCGTCAG CATGGCGTGT GTTGGGTTCT TCTTGCTGCA GGGGGCCTGG 
CCACATGAGG GAGTCCACAG AAAACCTTCC CTCCTGGCCC ACCCAGGTCG CCTGGTGAAA 
TCAGAAGAGA CAGTCATCCT GCAATGTTGG TCAGATGTCA GGTTTGAGCA CTTCCTTCTG 
CACAGAGAAG GGAAGTTTAA GGACACTTTG CACCTCATTG GAGAGCACCA TGATGGGGTC 
TCCAAAGCCA ACTTCTCCAT CGGTCCCATG ATGCAAGACC TTGCAGGGAC CTACAGATGC 
TACGGTTCTG TTACTCACTC CCCCTATCAG TTGTCAGCTC CCAGTGACCC TCTGGACATC 
GTCATCACAG GTCTATATGA GAAACCTTCT CTCTCAGCCC AGCCGGGCCC CACGGTTCTG 
GCAGGAGAGA GCGTGACCTT GTCCTGCAGC TCCCGGAGCT CCTATGACAT GTACCATCTA 
TCCAGGGAGG GGGAGGCCCA TGAATGTAGG TTCTCTGCAG GGCCCAAGGT CAACGGAACA 
TTCCAGGCCG ACTTTCCTCT GGGCCCTGCC ACCCACGGAG GAACCTACAG ATGCTTCGGC 
TCTTTCCGTG ACTCTCCATA CGAGTGGTCA AACTCGAGTG ACCCACTGCT TGTTTCTGTC 
ACAGGAAACC CTTCAAATAG TTGGCCTTCA CCCACTGAAC CAAGCTCTAA AACCGAGAGG 
ATGTTTCACC ACGTTGGCCA AGCTTGTCTG AAACTCCCAA CCTCAAGTGA TCCGACCGTC 
TCAGCATGCC AAAGTAACCC CCGACACCTG CACATTCTGA TTGGGACCTC AGTGGTCATC 
ATCCTCTTCA TCCTCCTCTT CTTTCTCCTT CATCGCTGGT GCTCCAACAA AAAAAATGCT 
GCGGTAATGG ACCAAGAGTC TGCAGGGAAC AGAACAGCGA ATAGCGAGGA CTCTGATGAA 
CAAGACCCTC AGGAGGTGAC ATACACACAG TTGAATCACT GCGTTTTCAC ACAGAGAAAA 
ATCACTCGCC CTTCTCAGAG GCCCAAGACA CCCCCAACAG ATATCATCGT GTACACGGAA 
CTTCCAAATG CTGAGTCCAG ATCCAAAGTT GTCTCCTGCC CATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016885735.1
CDS	157..1281
Translation	MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLLHREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGTFQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTERMFHHVGQACLKLPTSSDPTVSACQSNPRHLHILIGTSVVIILFILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKVVSCP

Target ORF information:

RefSeq Version	XM_017030246.1
Organism	Homo sapiens(human)
Definition	Homo sapiens killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2 (KIR2DL2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017030246.1

ORF Insert Sequence:

ATGTCGCTCA TGGTCGTCAG CATGGCGTGT GTTGGGTTCT TCTTGCTGCA GGGGGCCTGG 
CCACATGAGG GAGTCCACAG AAAACCTTCC CTCCTGGCCC ACCCAGGTCG CCTGGTGAAA 
TCAGAAGAGA CAGTCATCCT GCAATGTTGG TCAGATGTCA GGTTTGAGCA CTTCCTTCTG 
CACAGAGAAG GGAAGTTTAA GGACACTTTG CACCTCATTG GAGAGCACCA TGATGGGGTC 
TCCAAAGCCA ACTTCTCCAT CGGTCCCATG ATGCAAGACC TTGCAGGGAC CTACAGATGC 
TACGGTTCTG TTACTCACTC CCCCTATCAG TTGTCAGCTC CCAGTGACCC TCTGGACATC 
GTCATCACAG GTCTATATGA GAAACCTTCT CTCTCAGCCC AGCCGGGCCC CACGGTTCTG 
GCAGGAGAGA GCGTGACCTT GTCCTGCAGC TCCCGGAGCT CCTATGACAT GTACCATCTA 
TCCAGGGAGG GGGAGGCCCA TGAATGTAGG TTCTCTGCAG GGCCCAAGGT CAACGGAACA 
TTCCAGGCCG ACTTTCCTCT GGGCCCTGCC ACCCACGGAG GAACCTACAG ATGCTTCGGC 
TCTTTCCGTG ACTCTCCATA CGAGTGGTCA AACTCGAGTG ACCCACTGCT TGTTTCTGTC 
ACAGGAAACC CTTCAAATAG TTGGCCTTCA CCCACTGAAC CAAGCTCTAA AACCGAGAGG 
ATGTTTCACC ACGTTGGCCA AGCTTGTCTG AAACTCCCAA CCTCAAGTGA TCCGACCGTC 
TCAGCATGCC AAAGTAACCC CCGACACCTG CACATTCTGA TTGGGACCTC AGTGGTCATC 
ATCCTCTTCA TCCTCCTCTT CTTTCTCCTT CATCGCTGGT GCTCCAACAA AAAAAATGCT 
GCGGTAATGG ACCAAGAGTC TGCAGGGAAC AGAACAGCGA ATAGCGAGGA CTCTGATGAA 
CAAGACCCTC AGGAGGTGAC ATACACACAG TTGAATCACT GCGTTTTCAC ACAGAGAAAA 
ATCACTCGCC CTTCTCAGAG GCCCAAGACA CCCCCAACAG ATATCATCGT GTACACGGAA 
CTTCCAAATG CTGAGTCCAG ATCCAAAGTT GTCTCCTGCC CATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KIR2DL2 ( XM_017030270.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016885759.1 Homo sapiens killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2 (KIR2DL2), transcript variant X4, mRNA.

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CloneID	OHu100093
Clone ID Related Accession (Same CDS sequence)	XM_017030246.1 , XM_017030270.1
Accession Version	XM_017030270.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1125bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	killer cell immunoglobulin-like receptor 2DL2 isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_187670.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCGCTCA TGGTCGTCAG CATGGCGTGT GTTGGGTTCT TCTTGCTGCA GGGGGCCTGG 
CCACATGAGG GAGTCCACAG AAAACCTTCC CTCCTGGCCC ACCCAGGTCG CCTGGTGAAA 
TCAGAAGAGA CAGTCATCCT GCAATGTTGG TCAGATGTCA GGTTTGAGCA CTTCCTTCTG 
CACAGAGAAG GGAAGTTTAA GGACACTTTG CACCTCATTG GAGAGCACCA TGATGGGGTC 
TCCAAAGCCA ACTTCTCCAT CGGTCCCATG ATGCAAGACC TTGCAGGGAC CTACAGATGC 
TACGGTTCTG TTACTCACTC CCCCTATCAG TTGTCAGCTC CCAGTGACCC TCTGGACATC 
GTCATCACAG GTCTATATGA GAAACCTTCT CTCTCAGCCC AGCCGGGCCC CACGGTTCTG 
GCAGGAGAGA GCGTGACCTT GTCCTGCAGC TCCCGGAGCT CCTATGACAT GTACCATCTA 
TCCAGGGAGG GGGAGGCCCA TGAATGTAGG TTCTCTGCAG GGCCCAAGGT CAACGGAACA 
TTCCAGGCCG ACTTTCCTCT GGGCCCTGCC ACCCACGGAG GAACCTACAG ATGCTTCGGC 
TCTTTCCGTG ACTCTCCATA CGAGTGGTCA AACTCGAGTG ACCCACTGCT TGTTTCTGTC 
ACAGGAAACC CTTCAAATAG TTGGCCTTCA CCCACTGAAC CAAGCTCTAA AACCGAGAGG 
ATGTTTCACC ACGTTGGCCA AGCTTGTCTG AAACTCCCAA CCTCAAGTGA TCCGACCGTC 
TCAGCATGCC AAAGTAACCC CCGACACCTG CACATTCTGA TTGGGACCTC AGTGGTCATC 
ATCCTCTTCA TCCTCCTCTT CTTTCTCCTT CATCGCTGGT GCTCCAACAA AAAAAATGCT 
GCGGTAATGG ACCAAGAGTC TGCAGGGAAC AGAACAGCGA ATAGCGAGGA CTCTGATGAA 
CAAGACCCTC AGGAGGTGAC ATACACACAG TTGAATCACT GCGTTTTCAC ACAGAGAAAA 
ATCACTCGCC CTTCTCAGAG GCCCAAGACA CCCCCAACAG ATATCATCGT GTACACGGAA 
CTTCCAAATG CTGAGTCCAG ATCCAAAGTT GTCTCCTGCC CATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016885759.1
CDS	157..1281
Translation	MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLLHREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGTFQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTERMFHHVGQACLKLPTSSDPTVSACQSNPRHLHILIGTSVVIILFILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKVVSCP

Target ORF information:

RefSeq Version	XM_017030270.1
Organism	Homo sapiens(human)
Definition	Homo sapiens killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2 (KIR2DL2), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017030270.1

ORF Insert Sequence:

ATGTCGCTCA TGGTCGTCAG CATGGCGTGT GTTGGGTTCT TCTTGCTGCA GGGGGCCTGG 
CCACATGAGG GAGTCCACAG AAAACCTTCC CTCCTGGCCC ACCCAGGTCG CCTGGTGAAA 
TCAGAAGAGA CAGTCATCCT GCAATGTTGG TCAGATGTCA GGTTTGAGCA CTTCCTTCTG 
CACAGAGAAG GGAAGTTTAA GGACACTTTG CACCTCATTG GAGAGCACCA TGATGGGGTC 
TCCAAAGCCA ACTTCTCCAT CGGTCCCATG ATGCAAGACC TTGCAGGGAC CTACAGATGC 
TACGGTTCTG TTACTCACTC CCCCTATCAG TTGTCAGCTC CCAGTGACCC TCTGGACATC 
GTCATCACAG GTCTATATGA GAAACCTTCT CTCTCAGCCC AGCCGGGCCC CACGGTTCTG 
GCAGGAGAGA GCGTGACCTT GTCCTGCAGC TCCCGGAGCT CCTATGACAT GTACCATCTA 
TCCAGGGAGG GGGAGGCCCA TGAATGTAGG TTCTCTGCAG GGCCCAAGGT CAACGGAACA 
TTCCAGGCCG ACTTTCCTCT GGGCCCTGCC ACCCACGGAG GAACCTACAG ATGCTTCGGC 
TCTTTCCGTG ACTCTCCATA CGAGTGGTCA AACTCGAGTG ACCCACTGCT TGTTTCTGTC 
ACAGGAAACC CTTCAAATAG TTGGCCTTCA CCCACTGAAC CAAGCTCTAA AACCGAGAGG 
ATGTTTCACC ACGTTGGCCA AGCTTGTCTG AAACTCCCAA CCTCAAGTGA TCCGACCGTC 
TCAGCATGCC AAAGTAACCC CCGACACCTG CACATTCTGA TTGGGACCTC AGTGGTCATC 
ATCCTCTTCA TCCTCCTCTT CTTTCTCCTT CATCGCTGGT GCTCCAACAA AAAAAATGCT 
GCGGTAATGG ACCAAGAGTC TGCAGGGAAC AGAACAGCGA ATAGCGAGGA CTCTGATGAA 
CAAGACCCTC AGGAGGTGAC ATACACACAG TTGAATCACT GCGTTTTCAC ACAGAGAAAA 
ATCACTCGCC CTTCTCAGAG GCCCAAGACA CCCCCAACAG ATATCATCGT GTACACGGAA 
CTTCCAAATG CTGAGTCCAG ATCCAAAGTT GTCTCCTGCC CATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

HIV-1 Control by NK Cells via Reduced Interaction between KIR2DL2 and HLA-C
Cell reports17(9)2210-2220(2016 11)
Lin Z,Kuroki K,Kuse N,Sun X,Akahoshi T,Qi Y,Chikata T,Naruto T,Koyanagi M,Murakoshi H,Gatanaga H,Oka S,Carrington M,Maenaka K,Takiguchi M

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KIR2DL2 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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