KCNS3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	KCNS3
Entrez Gene ID	3790
Full Name	potassium voltage-gated channel modifier subfamily S member 3
Synonyms	KV9.3
General protein information	Preferred Names potassium voltage-gated channel modifier subfamily S member 3 Names potassium voltage-gated channel subfamily S member 3 Shab-related delayed-rectifier K+ channel alpha subunit 3 delayed-rectifier K(+) channel alpha subunit 3 potassium voltage-gated channel delayed-rectifier protein S3 potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3 voltage-gated potassium channel protein Kv9.3 voltage-gated potassium channel subunit Kv9.3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2p24.2
Summary	Voltage-gated potassium channels form the largest and most diversified class of ion channels and are present in both excitable and nonexcitable cells. Their main functions are associated with the regulation of the resting membrane potential and the control of the shape and frequency of action potentials. The alpha subunits are of 2 types: those that are functional by themselves and those that are electrically silent but capable of modulating the activity of specific functional alpha subunits. The protein encoded by this gene is not functional by itself but can form heteromultimers with member 1 and with member 2 (and possibly other members) of the Shab-related subfamily of potassium voltage-gated channel proteins. This gene belongs to the S subfamily of the potassium channel family. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2013].
Disorder MIM:	603888

mRNA and Protein(s)

mRNA	Protein	Name
XM_017004059.1	XP_016859548.1	potassium voltage-gated channel subfamily S member 3 isoform X1
XM_011532825.1	XP_011531127.1	potassium voltage-gated channel subfamily S member 3 isoform X1
NM_002252.4	NP_002243.3	potassium voltage-gated channel subfamily S member 3
NM_001282428.1	NP_001269357.1	potassium voltage-gated channel subfamily S member 3
NM_002252.5	NP_002243.3	potassium voltage-gated channel subfamily S member 3

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Kcns3	NP_001162036.1
Gallus gallus (chicken)	KCNS3	XP_426211.2
Bos taurus (cattle)	KCNS3	NP_001013624.1
Xenopus tropicalis (tropical clawed frog)	kcns3	XP_004918253.1
Homo sapiens (human)	KCNS3	NP_001269357.1
	KCNS3	XP_001093116.1
Canis lupus familiaris (dog)	KCNS3	XP_005630212.1
Rattus norvegicus (Norway rat)	Kcns3	NP_113966.2
Pan troglodytes (chimpanzee)	KCNS3	XP_001136873.1
Danio rerio (zebrafish)	zgc:194841	NP_001122196.1

Gene Ontology
Bibliography

Related articles in PubMed

Lower gene expression for KCNS3 potassium channel subunit in parvalbumin-containing neurons in the prefrontal cortex in schizophrenia.
Georgiev D, Arion D, Enwright JF, Kikuchi M, Minabe Y, Corradi JP, Lewis DA, Hashimoto T
The American journal of psychiatry171(1)62-71(2014 Jan)

Expression of an electrically silent voltage-gated potassium channel in the human placenta.
Fyfe GK, Panicker S, Jones RL, Wareing M
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology32(7)624-9(2012 Oct)

Expression and function of K(V)2-containing channels in human urinary bladder smooth muscle.
Hristov KL, Chen M, Afeli SA, Cheng Q, Rovner ES, Petkov GV
American journal of physiology. Cell physiology302(11)C1599-608(2012 Jun)

Stromatoxin-sensitive, heteromultimeric Kv2.1/Kv9.3 channels contribute to myogenic control of cerebral arterial diameter.
Zhong XZ, Abd-Elrahman KS, Liao CH, El-Yazbi AF, Walsh EJ, Walsh MP, Cole WC
The Journal of physiology588(Pt 22)4519-37(2010 Nov)

A high-density association screen of 155 ion transport genes for involvement with common migraine.
Nyholt DR, LaForge KS, Kallela M, Alakurtti K, Anttila V, F?rkkil? M, H?mal?inen E, Kaprio J, Kaunisto MA, Heath AC, Montgomery GW, G?bel H, Todt U, Ferrari MD, Launer LJ, Frants RR, Terwindt GM, de Vries B, Verschuren WM, Brand J, Freilinger T, Pfaffenrath V, Straube A, Ballinger DG, Zhan Y, Daly MJ, Cox DR, Dichgans M, van den Maagdenberg AM, Kubisch C, Martin NG, Wessman M, Peltonen L, Palotie A
Human molecular genetics17(21)3318-31(2008 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

By in situ hybridization, KCNS3 mRNA levels were 23% lower in schizophrenia subjects than in controls. At the cellular level, both KCNS3 mRNA-expressing neuron density and KCNS3 mRNA level per neuron were significantly lower.
Title: Lower gene expression for KCNS3 potassium channel subunit in parvalbumin-containing neurons in the prefrontal cortex in schizophrenia.

study concluded that potassium voltage-gated channel K(V)9.3 is localised to human placental vascular tissues and syncytiotrophoblast
Title: Expression of an electrically silent voltage-gated potassium channel in the human placenta.

stromatoxin-1 -sensitive KV2-containing channels are expressed in detrusor smooth muscle (DSM); they control DSM excitability, intracellular Ca2+ levels, and myogenic and nerve-evoked contractions
Title: Expression and function of K(V)2-containing channels in human urinary bladder smooth muscle.

There is evidence of heteromultimeric Kv2.1/Kv9.3 channel expression in control of middle cerebral arterial diameter.
Title: Stromatoxin-sensitive, heteromultimeric Kv2.1/Kv9.3 channels contribute to myogenic control of cerebral arterial diameter.

Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
Title: A high-density association screen of 155 ion transport genes for involvement with common migraine.

The following KCNS3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KCNS3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu58601	NM_002252.5 Latest version!	Homo sapiens potassium voltage-gated channel modifier subfamily S member 3 (KCNS3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu21392	NM_001282428.1 Latest version!	Homo sapiens potassium voltage-gated channel modifier subfamily S member 3 (KCNS3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu21392	NM_002252.4 Latest version!	Homo sapiens potassium voltage-gated channel modifier subfamily S member 3 (KCNS3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu58601	XM_017004059.1 Latest version!	Homo sapiens potassium voltage-gated channel modifier subfamily S member 3 (KCNS3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu58601	XM_011532825.1 Latest version!	Homo sapiens potassium voltage-gated channel modifier subfamily S member 3 (KCNS3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KCNS3 ( NM_002252.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_002243.3 Homo sapiens potassium voltage-gated channel modifier subfamily S member 3 (KCNS3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu58601
Clone ID Related Accession (Same CDS sequence)	XM_017004059.1 , XM_011532825.1 , NM_002252.5
Accession Version	NM_002252.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1476bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	potassium voltage-gated channel subfamily S member 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC093731.2. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_002252.4. Transcript Variant: This variant (1) and variant 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: BC015947.2, SRR1660809.153862.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000304101.9/ ENSP00000305824.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGTGTTTG GTGAGTTTTT CCATCGCCCT GGACAAGACG AGGAACTTGT CAACCTGAAT 
GTGGGGGGCT TTAAGCAGTC TGTTGACCAA AGCACCCTCC TGCGGTTTCC TCACACCAGA 
CTGGGGAAGC TGCTTACTTG CCATTCTGAA GAGGCCATTC TGGAGCTGTG TGATGATTAC 
AGTGTGGCCG ATAAGGAGTA CTACTTTGAT CGGAATCCCT CCTTGTTCAG ATATGTTTTG 
AATTTTTATT ACACGGGGAA GCTGCATGTC ATGGAGGAGC TGTGCGTATT CTCATTCTGC 
CAGGAGATCG AGTACTGGGG CATCAACGAG CTCTTCATTG ATTCTTGCTG CAGCAATCGC 
TACCAGGAAC GCAAGGAGGA AAACCACGAG AAGGACTGGG ACCAGAAAAG CCATGATGTG 
AGTACCGACT CCTCGTTTGA AGAGTCGTCT CTGTTTGAGA AAGAGCTGGA GAAGTTTGAC 
ACACTGCGAT TTGGTCAGCT CCGGAAGAAA ATCTGGATTA GAATGGAGAA TCCAGCGTAC 
TGCCTGTCCG CTAAGCTTAT CGCTATCTCC TCCTTGAGCG TGGTGCTGGC CTCCATCGTG 
GCCATGTGCG TTCACAGCAT GTCGGAGTTC CAGAATGAGG ATGGAGAAGT GGATGATCCG 
GTGCTGGAAG GAGTGGAGAT CGCGTGCATT GCCTGGTTCA CCGGGGAGCT TGCCGTCCGG 
CTGGCTGCCG CTCCTTGTCA AAAGAAATTC TGGAAAAACC CTCTGAACAT CATTGACTTT 
GTCTCTATTA TTCCCTTCTA TGCCACGTTG GCTGTAGACA CCAAGGAGGA AGAGAGTGAG 
GATATTGAGA ACATGGGCAA GGTGGTCCAG ATCCTACGGC TTATGAGGAT TTTCCGAATT 
CTAAAGCTTG CCCGGCACTC GGTAGGACTT CGGTCTCTAG GTGCCACACT GAGACACAGC 
TACCATGAAG TTGGGCTTCT GCTTCTCTTC CTCTCTGTGG GCATTTCCAT TTTCTCTGTG 
CTTATCTACT CCGTGGAGAA AGATGACCAC ACATCCAGCC TCACCAGCAT CCCCATCTGC 
TGGTGGTGGG CCACCATCAG CATGACAACT GTGGGCTATG GAGACACCCA CCCGGTCACC 
TTGGCGGGAA AGCTCATCGC CAGCACATGC ATCATCTGTG GCATCTTGGT GGTGGCCCTT 
CCCATCACCA TCATCTTCAA CAAGTTTTCC AAGTACTACC AGAAGCAAAA GGACATTGAT 
GTGGACCAGT GCAGTGAGGA TGCACCAGAG AAGTGTCATG AGCTACCTTA CTTTAACATT 
AGGGATATAT ATGCACAGCG GATGCACACC TTCATTACCA GTCTCTCTTC TGTAGGCATT 
GTGGTGAGCG ATCCTGACTC CACAGATGCT TCAAGCATTG AAGACAATGA GGACATTTGT 
AACACCACCT CCTTGGAGAA TTGCACAGCA AAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002243.3
CDS	392..1867
Translation	MVFGEFFHRPGQDEELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFDRNPSLFRYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHEKDWDQKSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPAYCLSAKLIAISSLSVVLASIVAMCVHSMSEFQNEDGEVDDPVLEGVEIACIAWFTGELAVRLAAAPCQKKFWKNPLNIIDFVSIIPFYATLAVDTKEEESEDIENMGKVVQILRLMRIFRILKLARHSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEKDDHTSSLTSIPICWWWATISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYYQKQKDIDVDQCSEDAPEKCHELPYFNIRDIYAQRMHTFITSLSSVGIVVSDPDSTDASSIEDNEDICNTTSLENCTAK

Target ORF information:

RefSeq Version	NM_002252.5
Organism	Homo sapiens(human)
Definition	Homo sapiens potassium voltage-gated channel modifier subfamily S member 3 (KCNS3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002252.5

ORF Insert Sequence:

ATGGTGTTTG GTGAGTTTTT CCATCGCCCT GGACAAGACG AGGAACTTGT CAACCTGAAT 
GTGGGGGGCT TTAAGCAGTC TGTTGACCAA AGCACCCTCC TGCGGTTTCC TCACACCAGA 
CTGGGGAAGC TGCTTACTTG CCATTCTGAA GAGGCCATTC TGGAGCTGTG TGATGATTAC 
AGTGTGGCCG ATAAGGAGTA CTACTTTGAT CGGAATCCCT CCTTGTTCAG ATATGTTTTG 
AATTTTTATT ACACGGGGAA GCTGCATGTC ATGGAGGAGC TGTGCGTATT CTCATTCTGC 
CAGGAGATCG AGTACTGGGG CATCAACGAG CTCTTCATTG ATTCTTGCTG CAGCAATCGC 
TACCAGGAAC GCAAGGAGGA AAACCACGAG AAGGACTGGG ACCAGAAAAG CCATGATGTG 
AGTACCGACT CCTCGTTTGA AGAGTCGTCT CTGTTTGAGA AAGAGCTGGA GAAGTTTGAC 
ACACTGCGAT TTGGTCAGCT CCGGAAGAAA ATCTGGATTA GAATGGAGAA TCCAGCGTAC 
TGCCTGTCCG CTAAGCTTAT CGCTATCTCC TCCTTGAGCG TGGTGCTGGC CTCCATCGTG 
GCCATGTGCG TTCACAGCAT GTCGGAGTTC CAGAATGAGG ATGGAGAAGT GGATGATCCG 
GTGCTGGAAG GAGTGGAGAT CGCGTGCATT GCCTGGTTCA CCGGGGAGCT TGCCGTCCGG 
CTGGCTGCCG CTCCTTGTCA AAAGAAATTC TGGAAAAACC CTCTGAACAT CATTGACTTT 
GTCTCTATTA TTCCCTTCTA TGCCACGTTG GCTGTAGACA CCAAGGAGGA AGAGAGTGAG 
GATATTGAGA ACATGGGCAA GGTGGTCCAG ATCCTACGGC TTATGAGGAT TTTCCGAATT 
CTAAAGCTTG CCCGGCACTC GGTAGGACTT CGGTCTCTAG GTGCCACACT GAGACACAGC 
TACCATGAAG TTGGGCTTCT GCTTCTCTTC CTCTCTGTGG GCATTTCCAT TTTCTCTGTG 
CTTATCTACT CCGTGGAGAA AGATGACCAC ACATCCAGCC TCACCAGCAT CCCCATCTGC 
TGGTGGTGGG CCACCATCAG CATGACAACT GTGGGCTATG GAGACACCCA CCCGGTCACC 
TTGGCGGGAA AGCTCATCGC CAGCACATGC ATCATCTGTG GCATCTTGGT GGTGGCCCTT 
CCCATCACCA TCATCTTCAA CAAGTTTTCC AAGTACTACC AGAAGCAAAA GGACATTGAT 
GTGGACCAGT GCAGTGAGGA TGCACCAGAG AAGTGTCATG AGCTACCTTA CTTTAACATT 
AGGGATATAT ATGCACAGCG GATGCACACC TTCATTACCA GTCTCTCTTC TGTAGGCATT 
GTGGTGAGCG ATCCTGACTC CACAGATGCT TCAAGCATTG AAGACAATGA GGACATTTGT 
AACACCACCT CCTTGGAGAA TTGCACAGCA AAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KCNS3 ( NM_002252.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_002243.3 Homo sapiens potassium voltage-gated channel modifier subfamily S member 3 (KCNS3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu21392
Clone ID Related Accession (Same CDS sequence)	NM_002252.4 , NM_001282428.1
Accession Version	NM_002252.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1476bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	potassium voltage-gated channel subfamily S member 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK314451.1 and BC015947.2. This sequence is a reference standard in the RefSeqGene project. On Sep 6, 2013 this sequence version replaced NM_002252.3. Transcript Variant: This variant (1) and variant 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: BC015947.2, SRR1660809.153862.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGTTTG GTGAGTTTTT CCATCGCCCT GGACAAGACG AGGAACTTGT CAACCTGAAT 
GTGGGGGGCT TTAAGCAGTC TGTTGACCAA AGCACCCTCC TGCGGTTTCC TCACACCAGA 
CTGGGGAAGC TGCTTACTTG CCATTCTGAA GAGGCCATTC TGGAGCTGTG TGATGATTAC 
AGTGTGGCCG ATAAGGAATA CTACTTTGAT CGGAATCCCT CCTTGTTCAG ATATGTTTTG 
AATTTTTATT ACACGGGGAA GCTGCATGTC ATGGAGGAGC TGTGCGTATT CTCATTCTGC 
CAGGAGATCG AGTACTGGGG CATCAACGAG CTCTTCATTG ATTCTTGCTG CAGCAATCGC 
TACCAGGAAC GCAAGGAGGA AAACCACGAG AAGGACTGGG ACCAGAAAAG CCATGATGTG 
AGTACCGACT CCTCGTTTGA AGAGTCGTCT CTGTTTGAGA AAGAGCTGGA GAAGTTTGAC 
ACACTGCGAT TTGGTCAGCT CCGGAAGAAA ATCTGGATTA GAATGGAGAA TCCAGCGTAC 
TGCCTGTCCG CTAAGCTTAT CGCTATCTCC TCCTTGAGCG TGGTGCTGGC CTCCATCGTG 
GCCATGTGCG TTCACAGCAT GTCGGAGTTC CAGAATGAGG ATGGAGAAGT GGATGATCCG 
GTGCTGGAAG GAGTGGAGAT CGCGTGCATT GCCTGGTTCA CCGGGGAGCT TGCCGTCCGG 
CTGGCTGCCG CTCCTTGTCA AAAGAAATTC TGGAAAAACC CTCTGAACAT CATTGACTTT 
GTCTCTATTA TTCCCTTCTA TGCCACGTTG GCTGTAGACA CCAAGGAGGA AGAGAGTGAG 
GATATTGAGA ACATGGGCAA GGTGGTCCAG ATCCTACGGC TTATGAGGAT TTTCCGAATT 
CTAAAGCTTG CCCGGCACTC GGTAGGACTT CGGTCTCTAG GTGCCACACT GAGACACAGC 
TACCATGAAG TTGGGCTTCT GCTTCTCTTC CTCTCTGTGG GCATTTCCAT TTTCTCTGTG 
CTTATCTACT CCGTGGAGAA AGATGACCAC ACATCCAGCC TCACCAGCAT CCCCATCTGC 
TGGTGGTGGG CCACCATCAG CATGACAACT GTGGGCTATG GAGACACCCA CCCGGTCACC 
TTGGCGGGAA AGCTCATCGC CAGCACATGC ATCATCTGTG GCATCTTGGT GGTGGCCCTT 
CCCATCACCA TCATCTTCAA CAAGTTTTCC AAGTACTACC AGAAGCAAAA GGACATTGAT 
GTGGACCAGT GCAGTGAGGA TGCACCAGAG AAGTGTCATG AGCTACCTTA CTTTAACATT 
AGGGATATAT ATGCACAGCG GATGCACACC TTCATTACCA GTCTCTCTTC TGTAGGCATT 
GTGGTGAGCG ATCCTGACTC CACAGATGCT TCAAGCATTG AAGACAATGA GGACATTTGT 
AACACCACCT CCTTGGAGAA TTGCACAGCA AAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002243.3
CDS	402..1877
Translation	MVFGEFFHRPGQDEELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFDRNPSLFRYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHEKDWDQKSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPAYCLSAKLIAISSLSVVLASIVAMCVHSMSEFQNEDGEVDDPVLEGVEIACIAWFTGELAVRLAAAPCQKKFWKNPLNIIDFVSIIPFYATLAVDTKEEESEDIENMGKVVQILRLMRIFRILKLARHSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEKDDHTSSLTSIPICWWWATISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYYQKQKDIDVDQCSEDAPEKCHELPYFNIRDIYAQRMHTFITSLSSVGIVVSDPDSTDASSIEDNEDICNTTSLENCTAK

Target ORF information:

RefSeq Version	NM_002252.4
Organism	Homo sapiens(human)
Definition	Homo sapiens potassium voltage-gated channel modifier subfamily S member 3 (KCNS3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002252.4

ORF Insert Sequence:

ATGGTGTTTG GTGAGTTTTT CCATCGCCCT GGACAAGACG AGGAACTTGT CAACCTGAAT 
GTGGGGGGCT TTAAGCAGTC TGTTGACCAA AGCACCCTCC TGCGGTTTCC TCACACCAGA 
CTGGGGAAGC TGCTTACTTG CCATTCTGAA GAGGCCATTC TGGAGCTGTG TGATGATTAC 
AGTGTGGCCG ATAAGGAATA CTACTTTGAT CGGAATCCCT CCTTGTTCAG ATATGTTTTG 
AATTTTTATT ACACGGGGAA GCTGCATGTC ATGGAGGAGC TGTGCGTATT CTCATTCTGC 
CAGGAGATCG AGTACTGGGG CATCAACGAG CTCTTCATTG ATTCTTGCTG CAGCAATCGC 
TACCAGGAAC GCAAGGAGGA AAACCACGAG AAGGACTGGG ACCAGAAAAG CCATGATGTG 
AGTACCGACT CCTCGTTTGA AGAGTCGTCT CTGTTTGAGA AAGAGCTGGA GAAGTTTGAC 
ACACTGCGAT TTGGTCAGCT CCGGAAGAAA ATCTGGATTA GAATGGAGAA TCCAGCGTAC 
TGCCTGTCCG CTAAGCTTAT CGCTATCTCC TCCTTGAGCG TGGTGCTGGC CTCCATCGTG 
GCCATGTGCG TTCACAGCAT GTCGGAGTTC CAGAATGAGG ATGGAGAAGT GGATGATCCG 
GTGCTGGAAG GAGTGGAGAT CGCGTGCATT GCCTGGTTCA CCGGGGAGCT TGCCGTCCGG 
CTGGCTGCCG CTCCTTGTCA AAAGAAATTC TGGAAAAACC CTCTGAACAT CATTGACTTT 
GTCTCTATTA TTCCCTTCTA TGCCACGTTG GCTGTAGACA CCAAGGAGGA AGAGAGTGAG 
GATATTGAGA ACATGGGCAA GGTGGTCCAG ATCCTACGGC TTATGAGGAT TTTCCGAATT 
CTAAAGCTTG CCCGGCACTC GGTAGGACTT CGGTCTCTAG GTGCCACACT GAGACACAGC 
TACCATGAAG TTGGGCTTCT GCTTCTCTTC CTCTCTGTGG GCATTTCCAT TTTCTCTGTG 
CTTATCTACT CCGTGGAGAA AGATGACCAC ACATCCAGCC TCACCAGCAT CCCCATCTGC 
TGGTGGTGGG CCACCATCAG CATGACAACT GTGGGCTATG GAGACACCCA CCCGGTCACC 
TTGGCGGGAA AGCTCATCGC CAGCACATGC ATCATCTGTG GCATCTTGGT GGTGGCCCTT 
CCCATCACCA TCATCTTCAA CAAGTTTTCC AAGTACTACC AGAAGCAAAA GGACATTGAT 
GTGGACCAGT GCAGTGAGGA TGCACCAGAG AAGTGTCATG AGCTACCTTA CTTTAACATT 
AGGGATATAT ATGCACAGCG GATGCACACC TTCATTACCA GTCTCTCTTC TGTAGGCATT 
GTGGTGAGCG ATCCTGACTC CACAGATGCT TCAAGCATTG AAGACAATGA GGACATTTGT 
AACACCACCT CCTTGGAGAA TTGCACAGCA AAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KCNS3 ( NM_001282428.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269357.1 Homo sapiens potassium voltage-gated channel modifier subfamily S member 3 (KCNS3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu21392
Clone ID Related Accession (Same CDS sequence)	NM_002252.4 , NM_001282428.1
Accession Version	NM_001282428.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1476bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	potassium voltage-gated channel subfamily S member 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA921825.1, AK314451.1 and BC015947.2. On Sep 6, 2013 this sequence version replaced XM_005262614.1. Transcript Variant: This variant (2) has an alternate 5' terminal exon, compared to variant 1. Both variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: AK225833.1, SRR1803612.268897.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142363, SAMEA2142853 [ECO:0000348] ##Evidence-Data-END##

ATGGTGTTTG GTGAGTTTTT CCATCGCCCT GGACAAGACG AGGAACTTGT CAACCTGAAT 
GTGGGGGGCT TTAAGCAGTC TGTTGACCAA AGCACCCTCC TGCGGTTTCC TCACACCAGA 
CTGGGGAAGC TGCTTACTTG CCATTCTGAA GAGGCCATTC TGGAGCTGTG TGATGATTAC 
AGTGTGGCCG ATAAGGAATA CTACTTTGAT CGGAATCCCT CCTTGTTCAG ATATGTTTTG 
AATTTTTATT ACACGGGGAA GCTGCATGTC ATGGAGGAGC TGTGCGTATT CTCATTCTGC 
CAGGAGATCG AGTACTGGGG CATCAACGAG CTCTTCATTG ATTCTTGCTG CAGCAATCGC 
TACCAGGAAC GCAAGGAGGA AAACCACGAG AAGGACTGGG ACCAGAAAAG CCATGATGTG 
AGTACCGACT CCTCGTTTGA AGAGTCGTCT CTGTTTGAGA AAGAGCTGGA GAAGTTTGAC 
ACACTGCGAT TTGGTCAGCT CCGGAAGAAA ATCTGGATTA GAATGGAGAA TCCAGCGTAC 
TGCCTGTCCG CTAAGCTTAT CGCTATCTCC TCCTTGAGCG TGGTGCTGGC CTCCATCGTG 
GCCATGTGCG TTCACAGCAT GTCGGAGTTC CAGAATGAGG ATGGAGAAGT GGATGATCCG 
GTGCTGGAAG GAGTGGAGAT CGCGTGCATT GCCTGGTTCA CCGGGGAGCT TGCCGTCCGG 
CTGGCTGCCG CTCCTTGTCA AAAGAAATTC TGGAAAAACC CTCTGAACAT CATTGACTTT 
GTCTCTATTA TTCCCTTCTA TGCCACGTTG GCTGTAGACA CCAAGGAGGA AGAGAGTGAG 
GATATTGAGA ACATGGGCAA GGTGGTCCAG ATCCTACGGC TTATGAGGAT TTTCCGAATT 
CTAAAGCTTG CCCGGCACTC GGTAGGACTT CGGTCTCTAG GTGCCACACT GAGACACAGC 
TACCATGAAG TTGGGCTTCT GCTTCTCTTC CTCTCTGTGG GCATTTCCAT TTTCTCTGTG 
CTTATCTACT CCGTGGAGAA AGATGACCAC ACATCCAGCC TCACCAGCAT CCCCATCTGC 
TGGTGGTGGG CCACCATCAG CATGACAACT GTGGGCTATG GAGACACCCA CCCGGTCACC 
TTGGCGGGAA AGCTCATCGC CAGCACATGC ATCATCTGTG GCATCTTGGT GGTGGCCCTT 
CCCATCACCA TCATCTTCAA CAAGTTTTCC AAGTACTACC AGAAGCAAAA GGACATTGAT 
GTGGACCAGT GCAGTGAGGA TGCACCAGAG AAGTGTCATG AGCTACCTTA CTTTAACATT 
AGGGATATAT ATGCACAGCG GATGCACACC TTCATTACCA GTCTCTCTTC TGTAGGCATT 
GTGGTGAGCG ATCCTGACTC CACAGATGCT TCAAGCATTG AAGACAATGA GGACATTTGT 
AACACCACCT CCTTGGAGAA TTGCACAGCA AAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269357.1
CDS	452..1927
Translation	MVFGEFFHRPGQDEELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFDRNPSLFRYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHEKDWDQKSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPAYCLSAKLIAISSLSVVLASIVAMCVHSMSEFQNEDGEVDDPVLEGVEIACIAWFTGELAVRLAAAPCQKKFWKNPLNIIDFVSIIPFYATLAVDTKEEESEDIENMGKVVQILRLMRIFRILKLARHSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEKDDHTSSLTSIPICWWWATISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYYQKQKDIDVDQCSEDAPEKCHELPYFNIRDIYAQRMHTFITSLSSVGIVVSDPDSTDASSIEDNEDICNTTSLENCTAK

Target ORF information:

RefSeq Version	NM_001282428.1
Organism	Homo sapiens(human)
Definition	Homo sapiens potassium voltage-gated channel modifier subfamily S member 3 (KCNS3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282428.1

ORF Insert Sequence:

ATGGTGTTTG GTGAGTTTTT CCATCGCCCT GGACAAGACG AGGAACTTGT CAACCTGAAT 
GTGGGGGGCT TTAAGCAGTC TGTTGACCAA AGCACCCTCC TGCGGTTTCC TCACACCAGA 
CTGGGGAAGC TGCTTACTTG CCATTCTGAA GAGGCCATTC TGGAGCTGTG TGATGATTAC 
AGTGTGGCCG ATAAGGAATA CTACTTTGAT CGGAATCCCT CCTTGTTCAG ATATGTTTTG 
AATTTTTATT ACACGGGGAA GCTGCATGTC ATGGAGGAGC TGTGCGTATT CTCATTCTGC 
CAGGAGATCG AGTACTGGGG CATCAACGAG CTCTTCATTG ATTCTTGCTG CAGCAATCGC 
TACCAGGAAC GCAAGGAGGA AAACCACGAG AAGGACTGGG ACCAGAAAAG CCATGATGTG 
AGTACCGACT CCTCGTTTGA AGAGTCGTCT CTGTTTGAGA AAGAGCTGGA GAAGTTTGAC 
ACACTGCGAT TTGGTCAGCT CCGGAAGAAA ATCTGGATTA GAATGGAGAA TCCAGCGTAC 
TGCCTGTCCG CTAAGCTTAT CGCTATCTCC TCCTTGAGCG TGGTGCTGGC CTCCATCGTG 
GCCATGTGCG TTCACAGCAT GTCGGAGTTC CAGAATGAGG ATGGAGAAGT GGATGATCCG 
GTGCTGGAAG GAGTGGAGAT CGCGTGCATT GCCTGGTTCA CCGGGGAGCT TGCCGTCCGG 
CTGGCTGCCG CTCCTTGTCA AAAGAAATTC TGGAAAAACC CTCTGAACAT CATTGACTTT 
GTCTCTATTA TTCCCTTCTA TGCCACGTTG GCTGTAGACA CCAAGGAGGA AGAGAGTGAG 
GATATTGAGA ACATGGGCAA GGTGGTCCAG ATCCTACGGC TTATGAGGAT TTTCCGAATT 
CTAAAGCTTG CCCGGCACTC GGTAGGACTT CGGTCTCTAG GTGCCACACT GAGACACAGC 
TACCATGAAG TTGGGCTTCT GCTTCTCTTC CTCTCTGTGG GCATTTCCAT TTTCTCTGTG 
CTTATCTACT CCGTGGAGAA AGATGACCAC ACATCCAGCC TCACCAGCAT CCCCATCTGC 
TGGTGGTGGG CCACCATCAG CATGACAACT GTGGGCTATG GAGACACCCA CCCGGTCACC 
TTGGCGGGAA AGCTCATCGC CAGCACATGC ATCATCTGTG GCATCTTGGT GGTGGCCCTT 
CCCATCACCA TCATCTTCAA CAAGTTTTCC AAGTACTACC AGAAGCAAAA GGACATTGAT 
GTGGACCAGT GCAGTGAGGA TGCACCAGAG AAGTGTCATG AGCTACCTTA CTTTAACATT 
AGGGATATAT ATGCACAGCG GATGCACACC TTCATTACCA GTCTCTCTTC TGTAGGCATT 
GTGGTGAGCG ATCCTGACTC CACAGATGCT TCAAGCATTG AAGACAATGA GGACATTTGT 
AACACCACCT CCTTGGAGAA TTGCACAGCA AAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KCNS3 ( XM_017004059.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016859548.1 Homo sapiens potassium voltage-gated channel modifier subfamily S member 3 (KCNS3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu58601
Clone ID Related Accession (Same CDS sequence)	XM_017004059.1 , XM_011532825.1 , NM_002252.5
Accession Version	XM_017004059.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1476bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	potassium voltage-gated channel subfamily S member 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGTTTG GTGAGTTTTT CCATCGCCCT GGACAAGACG AGGAACTTGT CAACCTGAAT 
GTGGGGGGCT TTAAGCAGTC TGTTGACCAA AGCACCCTCC TGCGGTTTCC TCACACCAGA 
CTGGGGAAGC TGCTTACTTG CCATTCTGAA GAGGCCATTC TGGAGCTGTG TGATGATTAC 
AGTGTGGCCG ATAAGGAGTA CTACTTTGAT CGGAATCCCT CCTTGTTCAG ATATGTTTTG 
AATTTTTATT ACACGGGGAA GCTGCATGTC ATGGAGGAGC TGTGCGTATT CTCATTCTGC 
CAGGAGATCG AGTACTGGGG CATCAACGAG CTCTTCATTG ATTCTTGCTG CAGCAATCGC 
TACCAGGAAC GCAAGGAGGA AAACCACGAG AAGGACTGGG ACCAGAAAAG CCATGATGTG 
AGTACCGACT CCTCGTTTGA AGAGTCGTCT CTGTTTGAGA AAGAGCTGGA GAAGTTTGAC 
ACACTGCGAT TTGGTCAGCT CCGGAAGAAA ATCTGGATTA GAATGGAGAA TCCAGCGTAC 
TGCCTGTCCG CTAAGCTTAT CGCTATCTCC TCCTTGAGCG TGGTGCTGGC CTCCATCGTG 
GCCATGTGCG TTCACAGCAT GTCGGAGTTC CAGAATGAGG ATGGAGAAGT GGATGATCCG 
GTGCTGGAAG GAGTGGAGAT CGCGTGCATT GCCTGGTTCA CCGGGGAGCT TGCCGTCCGG 
CTGGCTGCCG CTCCTTGTCA AAAGAAATTC TGGAAAAACC CTCTGAACAT CATTGACTTT 
GTCTCTATTA TTCCCTTCTA TGCCACGTTG GCTGTAGACA CCAAGGAGGA AGAGAGTGAG 
GATATTGAGA ACATGGGCAA GGTGGTCCAG ATCCTACGGC TTATGAGGAT TTTCCGAATT 
CTAAAGCTTG CCCGGCACTC GGTAGGACTT CGGTCTCTAG GTGCCACACT GAGACACAGC 
TACCATGAAG TTGGGCTTCT GCTTCTCTTC CTCTCTGTGG GCATTTCCAT TTTCTCTGTG 
CTTATCTACT CCGTGGAGAA AGATGACCAC ACATCCAGCC TCACCAGCAT CCCCATCTGC 
TGGTGGTGGG CCACCATCAG CATGACAACT GTGGGCTATG GAGACACCCA CCCGGTCACC 
TTGGCGGGAA AGCTCATCGC CAGCACATGC ATCATCTGTG GCATCTTGGT GGTGGCCCTT 
CCCATCACCA TCATCTTCAA CAAGTTTTCC AAGTACTACC AGAAGCAAAA GGACATTGAT 
GTGGACCAGT GCAGTGAGGA TGCACCAGAG AAGTGTCATG AGCTACCTTA CTTTAACATT 
AGGGATATAT ATGCACAGCG GATGCACACC TTCATTACCA GTCTCTCTTC TGTAGGCATT 
GTGGTGAGCG ATCCTGACTC CACAGATGCT TCAAGCATTG AAGACAATGA GGACATTTGT 
AACACCACCT CCTTGGAGAA TTGCACAGCA AAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016859548.1
CDS	352..1827
Translation	MVFGEFFHRPGQDEELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFDRNPSLFRYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHEKDWDQKSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPAYCLSAKLIAISSLSVVLASIVAMCVHSMSEFQNEDGEVDDPVLEGVEIACIAWFTGELAVRLAAAPCQKKFWKNPLNIIDFVSIIPFYATLAVDTKEEESEDIENMGKVVQILRLMRIFRILKLARHSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEKDDHTSSLTSIPICWWWATISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYYQKQKDIDVDQCSEDAPEKCHELPYFNIRDIYAQRMHTFITSLSSVGIVVSDPDSTDASSIEDNEDICNTTSLENCTAK

Target ORF information:

RefSeq Version	XM_017004059.1
Organism	Homo sapiens(human)
Definition	Homo sapiens potassium voltage-gated channel modifier subfamily S member 3 (KCNS3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017004059.1

ORF Insert Sequence:

ATGGTGTTTG GTGAGTTTTT CCATCGCCCT GGACAAGACG AGGAACTTGT CAACCTGAAT 
GTGGGGGGCT TTAAGCAGTC TGTTGACCAA AGCACCCTCC TGCGGTTTCC TCACACCAGA 
CTGGGGAAGC TGCTTACTTG CCATTCTGAA GAGGCCATTC TGGAGCTGTG TGATGATTAC 
AGTGTGGCCG ATAAGGAGTA CTACTTTGAT CGGAATCCCT CCTTGTTCAG ATATGTTTTG 
AATTTTTATT ACACGGGGAA GCTGCATGTC ATGGAGGAGC TGTGCGTATT CTCATTCTGC 
CAGGAGATCG AGTACTGGGG CATCAACGAG CTCTTCATTG ATTCTTGCTG CAGCAATCGC 
TACCAGGAAC GCAAGGAGGA AAACCACGAG AAGGACTGGG ACCAGAAAAG CCATGATGTG 
AGTACCGACT CCTCGTTTGA AGAGTCGTCT CTGTTTGAGA AAGAGCTGGA GAAGTTTGAC 
ACACTGCGAT TTGGTCAGCT CCGGAAGAAA ATCTGGATTA GAATGGAGAA TCCAGCGTAC 
TGCCTGTCCG CTAAGCTTAT CGCTATCTCC TCCTTGAGCG TGGTGCTGGC CTCCATCGTG 
GCCATGTGCG TTCACAGCAT GTCGGAGTTC CAGAATGAGG ATGGAGAAGT GGATGATCCG 
GTGCTGGAAG GAGTGGAGAT CGCGTGCATT GCCTGGTTCA CCGGGGAGCT TGCCGTCCGG 
CTGGCTGCCG CTCCTTGTCA AAAGAAATTC TGGAAAAACC CTCTGAACAT CATTGACTTT 
GTCTCTATTA TTCCCTTCTA TGCCACGTTG GCTGTAGACA CCAAGGAGGA AGAGAGTGAG 
GATATTGAGA ACATGGGCAA GGTGGTCCAG ATCCTACGGC TTATGAGGAT TTTCCGAATT 
CTAAAGCTTG CCCGGCACTC GGTAGGACTT CGGTCTCTAG GTGCCACACT GAGACACAGC 
TACCATGAAG TTGGGCTTCT GCTTCTCTTC CTCTCTGTGG GCATTTCCAT TTTCTCTGTG 
CTTATCTACT CCGTGGAGAA AGATGACCAC ACATCCAGCC TCACCAGCAT CCCCATCTGC 
TGGTGGTGGG CCACCATCAG CATGACAACT GTGGGCTATG GAGACACCCA CCCGGTCACC 
TTGGCGGGAA AGCTCATCGC CAGCACATGC ATCATCTGTG GCATCTTGGT GGTGGCCCTT 
CCCATCACCA TCATCTTCAA CAAGTTTTCC AAGTACTACC AGAAGCAAAA GGACATTGAT 
GTGGACCAGT GCAGTGAGGA TGCACCAGAG AAGTGTCATG AGCTACCTTA CTTTAACATT 
AGGGATATAT ATGCACAGCG GATGCACACC TTCATTACCA GTCTCTCTTC TGTAGGCATT 
GTGGTGAGCG ATCCTGACTC CACAGATGCT TCAAGCATTG AAGACAATGA GGACATTTGT 
AACACCACCT CCTTGGAGAA TTGCACAGCA AAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KCNS3 ( XM_011532825.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011531127.1 Homo sapiens potassium voltage-gated channel modifier subfamily S member 3 (KCNS3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu58601
Clone ID Related Accession (Same CDS sequence)	XM_017004059.1 , XM_011532825.1 , NM_002252.5
Accession Version	XM_011532825.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1476bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	potassium voltage-gated channel subfamily S member 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGTTTG GTGAGTTTTT CCATCGCCCT GGACAAGACG AGGAACTTGT CAACCTGAAT 
GTGGGGGGCT TTAAGCAGTC TGTTGACCAA AGCACCCTCC TGCGGTTTCC TCACACCAGA 
CTGGGGAAGC TGCTTACTTG CCATTCTGAA GAGGCCATTC TGGAGCTGTG TGATGATTAC 
AGTGTGGCCG ATAAGGAGTA CTACTTTGAT CGGAATCCCT CCTTGTTCAG ATATGTTTTG 
AATTTTTATT ACACGGGGAA GCTGCATGTC ATGGAGGAGC TGTGCGTATT CTCATTCTGC 
CAGGAGATCG AGTACTGGGG CATCAACGAG CTCTTCATTG ATTCTTGCTG CAGCAATCGC 
TACCAGGAAC GCAAGGAGGA AAACCACGAG AAGGACTGGG ACCAGAAAAG CCATGATGTG 
AGTACCGACT CCTCGTTTGA AGAGTCGTCT CTGTTTGAGA AAGAGCTGGA GAAGTTTGAC 
ACACTGCGAT TTGGTCAGCT CCGGAAGAAA ATCTGGATTA GAATGGAGAA TCCAGCGTAC 
TGCCTGTCCG CTAAGCTTAT CGCTATCTCC TCCTTGAGCG TGGTGCTGGC CTCCATCGTG 
GCCATGTGCG TTCACAGCAT GTCGGAGTTC CAGAATGAGG ATGGAGAAGT GGATGATCCG 
GTGCTGGAAG GAGTGGAGAT CGCGTGCATT GCCTGGTTCA CCGGGGAGCT TGCCGTCCGG 
CTGGCTGCCG CTCCTTGTCA AAAGAAATTC TGGAAAAACC CTCTGAACAT CATTGACTTT 
GTCTCTATTA TTCCCTTCTA TGCCACGTTG GCTGTAGACA CCAAGGAGGA AGAGAGTGAG 
GATATTGAGA ACATGGGCAA GGTGGTCCAG ATCCTACGGC TTATGAGGAT TTTCCGAATT 
CTAAAGCTTG CCCGGCACTC GGTAGGACTT CGGTCTCTAG GTGCCACACT GAGACACAGC 
TACCATGAAG TTGGGCTTCT GCTTCTCTTC CTCTCTGTGG GCATTTCCAT TTTCTCTGTG 
CTTATCTACT CCGTGGAGAA AGATGACCAC ACATCCAGCC TCACCAGCAT CCCCATCTGC 
TGGTGGTGGG CCACCATCAG CATGACAACT GTGGGCTATG GAGACACCCA CCCGGTCACC 
TTGGCGGGAA AGCTCATCGC CAGCACATGC ATCATCTGTG GCATCTTGGT GGTGGCCCTT 
CCCATCACCA TCATCTTCAA CAAGTTTTCC AAGTACTACC AGAAGCAAAA GGACATTGAT 
GTGGACCAGT GCAGTGAGGA TGCACCAGAG AAGTGTCATG AGCTACCTTA CTTTAACATT 
AGGGATATAT ATGCACAGCG GATGCACACC TTCATTACCA GTCTCTCTTC TGTAGGCATT 
GTGGTGAGCG ATCCTGACTC CACAGATGCT TCAAGCATTG AAGACAATGA GGACATTTGT 
AACACCACCT CCTTGGAGAA TTGCACAGCA AAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011531127.1
CDS	763..2238
Translation	MVFGEFFHRPGQDEELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFDRNPSLFRYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHEKDWDQKSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPAYCLSAKLIAISSLSVVLASIVAMCVHSMSEFQNEDGEVDDPVLEGVEIACIAWFTGELAVRLAAAPCQKKFWKNPLNIIDFVSIIPFYATLAVDTKEEESEDIENMGKVVQILRLMRIFRILKLARHSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEKDDHTSSLTSIPICWWWATISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYYQKQKDIDVDQCSEDAPEKCHELPYFNIRDIYAQRMHTFITSLSSVGIVVSDPDSTDASSIEDNEDICNTTSLENCTAK

Target ORF information:

RefSeq Version	XM_011532825.1
Organism	Homo sapiens(human)
Definition	Homo sapiens potassium voltage-gated channel modifier subfamily S member 3 (KCNS3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011532825.1

ORF Insert Sequence:

ATGGTGTTTG GTGAGTTTTT CCATCGCCCT GGACAAGACG AGGAACTTGT CAACCTGAAT 
GTGGGGGGCT TTAAGCAGTC TGTTGACCAA AGCACCCTCC TGCGGTTTCC TCACACCAGA 
CTGGGGAAGC TGCTTACTTG CCATTCTGAA GAGGCCATTC TGGAGCTGTG TGATGATTAC 
AGTGTGGCCG ATAAGGAGTA CTACTTTGAT CGGAATCCCT CCTTGTTCAG ATATGTTTTG 
AATTTTTATT ACACGGGGAA GCTGCATGTC ATGGAGGAGC TGTGCGTATT CTCATTCTGC 
CAGGAGATCG AGTACTGGGG CATCAACGAG CTCTTCATTG ATTCTTGCTG CAGCAATCGC 
TACCAGGAAC GCAAGGAGGA AAACCACGAG AAGGACTGGG ACCAGAAAAG CCATGATGTG 
AGTACCGACT CCTCGTTTGA AGAGTCGTCT CTGTTTGAGA AAGAGCTGGA GAAGTTTGAC 
ACACTGCGAT TTGGTCAGCT CCGGAAGAAA ATCTGGATTA GAATGGAGAA TCCAGCGTAC 
TGCCTGTCCG CTAAGCTTAT CGCTATCTCC TCCTTGAGCG TGGTGCTGGC CTCCATCGTG 
GCCATGTGCG TTCACAGCAT GTCGGAGTTC CAGAATGAGG ATGGAGAAGT GGATGATCCG 
GTGCTGGAAG GAGTGGAGAT CGCGTGCATT GCCTGGTTCA CCGGGGAGCT TGCCGTCCGG 
CTGGCTGCCG CTCCTTGTCA AAAGAAATTC TGGAAAAACC CTCTGAACAT CATTGACTTT 
GTCTCTATTA TTCCCTTCTA TGCCACGTTG GCTGTAGACA CCAAGGAGGA AGAGAGTGAG 
GATATTGAGA ACATGGGCAA GGTGGTCCAG ATCCTACGGC TTATGAGGAT TTTCCGAATT 
CTAAAGCTTG CCCGGCACTC GGTAGGACTT CGGTCTCTAG GTGCCACACT GAGACACAGC 
TACCATGAAG TTGGGCTTCT GCTTCTCTTC CTCTCTGTGG GCATTTCCAT TTTCTCTGTG 
CTTATCTACT CCGTGGAGAA AGATGACCAC ACATCCAGCC TCACCAGCAT CCCCATCTGC 
TGGTGGTGGG CCACCATCAG CATGACAACT GTGGGCTATG GAGACACCCA CCCGGTCACC 
TTGGCGGGAA AGCTCATCGC CAGCACATGC ATCATCTGTG GCATCTTGGT GGTGGCCCTT 
CCCATCACCA TCATCTTCAA CAAGTTTTCC AAGTACTACC AGAAGCAAAA GGACATTGAT 
GTGGACCAGT GCAGTGAGGA TGCACCAGAG AAGTGTCATG AGCTACCTTA CTTTAACATT 
AGGGATATAT ATGCACAGCG GATGCACACC TTCATTACCA GTCTCTCTTC TGTAGGCATT 
GTGGTGAGCG ATCCTGACTC CACAGATGCT TCAAGCATTG AAGACAATGA GGACATTTGT 
AACACCACCT CCTTGGAGAA TTGCACAGCA AAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Lower gene expression for KCNS3 potassium channel subunit in parvalbumin-containing neurons in the prefrontal cortex in schizophrenia.
The American journal of psychiatry171(1)62-71(2014 Jan)
Georgiev D,Arion D,Enwright JF,Kikuchi M,Minabe Y,Corradi JP,Lewis DA,Hashimoto T

Expression of an electrically silent voltage-gated potassium channel in the human placenta.
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology32(7)624-9(2012 Oct)
Fyfe GK,Panicker S,Jones RL,Wareing M

Expression and function of K(V)2-containing channels in human urinary bladder smooth muscle.
American journal of physiology. Cell physiology302(11)C1599-608(2012 Jun)
Hristov KL,Chen M,Afeli SA,Cheng Q,Rovner ES,Petkov GV

Stromatoxin-sensitive, heteromultimeric Kv2.1/Kv9.3 channels contribute to myogenic control of cerebral arterial diameter.
The Journal of physiology588(Pt 22)4519-37(2010 Nov)
Zhong XZ,Abd-Elrahman KS,Liao CH,El-Yazbi AF,Walsh EJ,Walsh MP,Cole WC

A high-density association screen of 155 ion transport genes for involvement with common migraine.
Human molecular genetics17(21)3318-31(2008 Nov)
Nyholt DR,LaForge KS,Kallela M,Alakurtti K,Anttila V,F?rkkil? M,H?mal?inen E,Kaprio J,Kaunisto MA,Heath AC,Montgomery GW,G?bel H,Todt U,Ferrari MD,Launer LJ,Frants RR,Terwindt GM,de Vries B,Verschuren WM,Brand J,Freilinger T,Pfaffenrath V,Straube A,Ballinger DG,Zhan Y,Daly MJ,Cox DR,Dichgans M,van den Maagdenberg AM,Kubisch C,Martin NG,Wessman M,Peltonen L,Palotie A

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KCNS3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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