KCNC3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	KCNC3
Entrez Gene ID	3748
Full Name	potassium voltage-gated channel subfamily C member 3
Synonyms	KSHIIID,KV3.3,SCA13
General protein information	Preferred Names potassium voltage-gated channel subfamily C member 3 Names potassium voltage-gated channel subfamily C member 3 Shaw-related voltage-gated potassium channel protein 3 potassium channel, voltage gated Shaw related subfamily C, member 3 potassium voltage-gated channel, Shaw-related subfamily, member 3 voltage-gated potassium channel protein KV3.3 voltage-gated potassium channel subunit Kv3.3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.33
Summary	The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to one of these subfamilies, namely the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. Alternate splicing results in several transcript variants. [provided by RefSeq, Mar 2014].
Disorder MIM:	176264
Disorder Html:	Spinocerebellar ataxia 13, 605259 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_004977.2	NP_004968.2	potassium voltage-gated channel subfamily C member 3
NM_001372305.1	NP_001359234.1	potassium voltage-gated channel subfamily C member 3 isoform 2
XM_011526928.2	XP_011525230.1	potassium voltage-gated channel subfamily C member 3 isoform X2
XM_011526926.1	XP_011525228.1	potassium voltage-gated channel subfamily C member 3 isoform X1
XM_011526925.2	XP_011525227.1	potassium voltage-gated channel subfamily C member 3 isoform X3
XM_006723203.2	XP_006723266.1	potassium voltage-gated channel subfamily C member 3 isoform X1
NM_004977.3	NP_004968.2	potassium voltage-gated channel subfamily C member 3 isoform 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	KCNC3	NP_004968.2
Rattus norvegicus (Norway rat)	Kcnc3	NP_446449.2
Danio rerio (zebrafish)	kcnc3b	NP_001182170.1
Bos taurus (cattle)	KCNC3	XP_003587351.2
Mus musculus (house mouse)	Kcnc3	NP_032448.2
Danio rerio (zebrafish)	kcnc3a	NP_001182169.1
Xenopus tropicalis (tropical clawed frog)	LOC100497714	XP_002942184.2

Gene Ontology
Bibliography

Related articles in PubMed

A KCNC3 mutation causes a neurodevelopmental, non-progressive SCA13 subtype associated with dominant negative effects and aberrant EGFR trafficking.
Khare S, Nick JA, Zhang Y, Galeano K, Butler B, Khoshbouei H, Rayaprolu S, Hathorn T, Ranum LPW, Smithson L, Golde TE, Paucar M, Morse R, Raff M, Simon J, Nordenskj?ld M, Wirdefeldt K, Rincon-Limas DE, Lewis J, Kaczmarek LK, Fernandez-Funez P, Nick HS, Waters MF
PloS one12(5)e0173565(2017)

Kv3.3 potassium channels and spinocerebellar ataxia.
Zhang Y, Kaczmarek LK
The Journal of physiology594(16)4677-84(2016 08)

Kv3.3 Channels Bind Hax-1 and Arp2/3 to Assemble a Stable Local Actin Network that Regulates Channel Gating.
Zhang Y, Zhang XF, Fleming MR, Amiri A, El-Hassar L, Surguchev AA, Hyland C, Jenkins DP, Desai R, Brown MR, Gazula VR, Waters MF, Large CH, Horvath TL, Navaratnam D, Vaccarino FM, Forscher P, Kaczmarek LK
Cell165(2)434-448(2016 Apr)

Voltage-Gated K+ Channel, Kv3.3 Is Involved in Hemin-Induced K562 Differentiation.
Song MS, Choi SY, Ryu PD, Lee SY
PloS one11(2)e0148633(2016)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

results therefore confirm the KCNC3R423H allele as causative for SCA13, through a dominant negative effect on KCNC3WT and links with EGFR that account for dominant inheritance, congenital onset, and disease pathology
Title: A KCNC3 mutation causes a neurodevelopmental, non-progressive SCA13 subtype associated with dominant negative effects and aberrant EGFR trafficking.

This review covers the localization and physiological function of Kv3.3 in the central nervous system and how the normal function of the channel is altered by the disease-causing mutations
Title: Kv3.3 potassium channels and spinocerebellar ataxia.

Kv3.3 regulates Arp2/3-dependent cortical actin nucleation mediated by Hax-1; resulting cortical actin structures interact with the channel's gating machinery to slow its inactivation rate during sustained membrane depolarizations; a mutation that leads to late-onset spinocerebellar ataxia type 13.
Title: Kv3.3 Channels Bind Hax-1 and Arp2/3 to Assemble a Stable Local Actin Network that Regulates Channel Gating.

The Kv channels, or at least Kv3.3, appear to be associated with cell differentiation
Title: Voltage-Gated K+ Channel, Kv3.3 Is Involved in Hemin-Induced K562 Differentiation.

investigated using either targeted next generation sequencing or trio-based exome sequencing and were found to have mutations in three different genes, KCNC3, ITPR1 and SPTBN2
Title: De novo point mutations in patients diagnosed with ataxic cerebral palsy.

The following KCNC3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KCNC3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu108832	NM_001372305.1 Latest version!	Homo sapiens potassium voltage-gated channel subfamily C member 3 (KCNC3), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OHu25796	NM_004977.3 Latest version!	Homo sapiens potassium voltage-gated channel subfamily C member 3 (KCNC3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OHu25796	XM_011526926.1 Latest version!	Homo sapiens potassium voltage-gated channel subfamily C member 3 (KCNC3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
OHu25796	XM_006723203.2 Latest version!	Homo sapiens potassium voltage-gated channel subfamily C member 3 (KCNC3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
OHu58555	XM_011526925.2 Latest version!	Homo sapiens potassium voltage-gated channel subfamily C member 3 (KCNC3), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
OHu58556	XM_011526928.2 Latest version!	Homo sapiens potassium voltage-gated channel subfamily C member 3 (KCNC3), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
View Old Accession Versions >>
OHu25796	NM_004977.2	Homo sapiens potassium voltage-gated channel subfamily C member 3 (KCNC3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KCNC3 ( NM_001372305.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001359234.1 Homo sapiens potassium voltage-gated channel subfamily C member 3 (KCNC3), transcript variant 3, mRNA.

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CloneID	OHu108832
Clone ID Related Accession (Same CDS sequence)	NM_001372305.1
Accession Version	NM_001372305.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2046bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-29
Organism	Homo sapiens(human)
Product	potassium voltage-gated channel subfamily C member 3 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC008655.7. Transcript Variant: This variant (3) differs in the 5' UTR and coding region, compared to variant 1. The resulting isoform (2) has a shorter N-terminus compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF055989.1 [ECO:0000332] ##Evidence-Data-END##

ATGGGGCGGC ACGGCGGCGG CGGTGGCGAC AGCGGCAAGA TCGTGATCAA CGTGGGCGGC 
GTGCGCCATG AGACGTACCG CTCGACGCTG CGCACCCTGC CGGGGACGCG GCTGGCCGGC 
CTGACGGAGC CCGAGGCGGC GGCACGCTTC GACTACGACC CGGGCGCCGA CGAGTTCTTC 
TTTGACCGGC ACCCGGGAGT CTTCGCGTAC GTGCTCAACT ACTACCGCAC CGGCAAGCTG 
CACTGCCCAG CCGACGTGTG CGGGCCCCTG TTTGAGGAGG AGCTCGGCTT CTGGGGCATC 
GACGAGACCG ACGTGGAGGC CTGCTGCTGG ATGACCTACC GGCAGCATCG CGACGCTGAG 
GAGGCGCTCG ACTCCTTCGA GGCGCCCGAC CCCGCGGGCG CCGCCAACGC CGCCAACGCC 
GCAGGCGCCC ACGACGGAGG CCTGGACGAC GAGGCGGGCG CGGGCGGCGG CGGCCTGGAC 
GGAGCGGGCG GCGAGCTCAA GCGCCTCTGC TTCCAGGACG CGGGCGGCGG CGCCGGGGGG 
CCGCCAGGGG GCGCGGGCGG CGCGGGCGGC ACATGGTGGC GCCGCTGGCA GCCCCGCGTG 
TGGGCGCTCT TCGAGGACCC CTACTCGTCG CGGGCTGCCA GGTATGTGGC CTTCGCCTCC 
CTCTTCTTCA TCCTCATCTC CATCACCACC TTCTGCCTGG AAACCCATGA GGGCTTCATC 
CATATTAGCA ACAAGACGGT GACCCAGGCC TCCCCGATCC CCGGGGCACC TCCGGAGAAC 
ATCACCAACG TGGAGGTGGA GACGGAGCCC TTCCTGACCT ACGTGGAGGG GGTGTGCGTG 
GTCTGGTTCA CCTTCGAGTT CCTCATGCGC ATCACCTTCT GCCCAGACAA GGTGGAGTTT 
CTTAAAAGCA GCCTCAACAT CATCGACTGT GTGGCCATCC TGCCCTTCTA TCTCGAGGTG 
GGCCTCTCGG GCCTCAGCTC CAAGGCCGCC AAAGACGTGC TGGGCTTCCT GCGGGTGGTC 
CGCTTCGTCC GCATCCTGCG CATCTTCAAG CTGACCCGGC ACTTCGTGGG GCTGCGCGTG 
CTGGGACACA CGCTCCGCGC CAGCACCAAC GAGTTCCTGC TGCTCATCAT CTTCCTGGCC 
CTGGGGGTGC TCATCTTCGC CACCATGATT TACTACGCTG AGCGCATTGG CGCCGACCCC 
GATGACATCC TGGGCTCCAA CCACACCTAC TTCAAGAACA TCCCCATTGG CTTCTGGTGG 
GCTGTGGTCA CCATGACGAC CCTGGGCTAT GGAGACATGT ACCCCAAGAC GTGGTCGGGG 
ATGCTGGTCG GGGCGCTGTG TGCCCTGGCG GGGGTGCTGA CCATCGCCAT GCCTGTGCCC 
GTCATTGTCA ACAACTTTGG CATGTACTAT TCGCTGGCCA TGGCCAAGCA GAAGCTGCCC 
AAGAAGAAGA ACAAACACAT CCCCCGGCCC CCGCAACCGG GCTCGCCCAA CTACTGCAAG 
CCTGACCCAC CCCCGCCACC CCCGCCCCAC CCGCACCACG GCAGCGGGGG CATCAGCCCG 
CCGCCACCCA TCACCCCACC CTCCATGGGG GTGACTGTGG CCGGGGCCTA CCCAGCGGGG 
CCCCACACGC ACCCCGGGCT GCTCAGGGGG GGAGCGGGTG GGCTGGGGAT CATGGGGCTG 
CCTCCTCTGC CAGCCCCCGG CGAGCCTTGC CCGTTGGCTC AGGAGGAGGT GATTGAGATC 
AACCGGGCAG ATCCTCGCCC CAATGGGGAT CCGGCAGCAG CTGCGCTTGC CCACGAGGAC 
TGCCCAGCCA TTGACCAGCC TGCCATGTCC CCGGAAGACA AGAGCCCCAT CACGCCTGGA 
AGCCGTGGCC GCTATAGCCG GGACCGAGCC TGCTTCCTCC TCACCGACTA TGCCCCTTCC 
CCTGATGGCT CCATCCGAAA AGCCACTGGT GCTCCCCCAC TGCCCCCCCA AGACTGGCGT 
AAGCCAGGCC CCCCAAGCTT CTTGCCCGAC CTCAACGCCA ACGCCGCGGC CTGGATATCC 
CCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001359234.1
CDS	218..2263
Translation	MGRHGGGGGDSGKIVINVGGVRHETYRSTLRTLPGTRLAGLTEPEAAARFDYDPGADEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELGFWGIDETDVEACCWMTYRQHRDAEEALDSFEAPDPAGAANAANAAGAHDGGLDDEAGAGGGGLDGAGGELKRLCFQDAGGGAGGPPGGAGGAGGTWWRRWQPRVWALFEDPYSSRAARYVAFASLFFILISITTFCLETHEGFIHISNKTVTQASPIPGAPPENITNVEVETEPFLTYVEGVCVVWFTFEFLMRITFCPDKVEFLKSSLNIIDCVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDILGSNHTYFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIPRPPQPGSPNYCKPDPPPPPPPHPHHGSGGISPPPPITPPSMGVTVAGAYPAGPHTHPGLLRGGAGGLGIMGLPPLPAPGEPCPLAQEEVIEINRADPRPNGDPAAAALAHEDCPAIDQPAMSPEDKSPITPGSRGRYSRDRACFLLTDYAPSPDGSIRKATGAPPLPPQDWRKPGPPSFLPDLNANAAAWISP

Target ORF information:

RefSeq Version	NM_001372305.1
Organism	Homo sapiens(human)
Definition	Homo sapiens potassium voltage-gated channel subfamily C member 3 (KCNC3), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001372305.1

ORF Insert Sequence:

ATGGGGCGGC ACGGCGGCGG CGGTGGCGAC AGCGGCAAGA TCGTGATCAA CGTGGGCGGC 
GTGCGCCATG AGACGTACCG CTCGACGCTG CGCACCCTGC CGGGGACGCG GCTGGCCGGC 
CTGACGGAGC CCGAGGCGGC GGCACGCTTC GACTACGACC CGGGCGCCGA CGAGTTCTTC 
TTTGACCGGC ACCCGGGAGT CTTCGCGTAC GTGCTCAACT ACTACCGCAC CGGCAAGCTG 
CACTGCCCAG CCGACGTGTG CGGGCCCCTG TTTGAGGAGG AGCTCGGCTT CTGGGGCATC 
GACGAGACCG ACGTGGAGGC CTGCTGCTGG ATGACCTACC GGCAGCATCG CGACGCTGAG 
GAGGCGCTCG ACTCCTTCGA GGCGCCCGAC CCCGCGGGCG CCGCCAACGC CGCCAACGCC 
GCAGGCGCCC ACGACGGAGG CCTGGACGAC GAGGCGGGCG CGGGCGGCGG CGGCCTGGAC 
GGAGCGGGCG GCGAGCTCAA GCGCCTCTGC TTCCAGGACG CGGGCGGCGG CGCCGGGGGG 
CCGCCAGGGG GCGCGGGCGG CGCGGGCGGC ACATGGTGGC GCCGCTGGCA GCCCCGCGTG 
TGGGCGCTCT TCGAGGACCC CTACTCGTCG CGGGCTGCCA GGTATGTGGC CTTCGCCTCC 
CTCTTCTTCA TCCTCATCTC CATCACCACC TTCTGCCTGG AAACCCATGA GGGCTTCATC 
CATATTAGCA ACAAGACGGT GACCCAGGCC TCCCCGATCC CCGGGGCACC TCCGGAGAAC 
ATCACCAACG TGGAGGTGGA GACGGAGCCC TTCCTGACCT ACGTGGAGGG GGTGTGCGTG 
GTCTGGTTCA CCTTCGAGTT CCTCATGCGC ATCACCTTCT GCCCAGACAA GGTGGAGTTT 
CTTAAAAGCA GCCTCAACAT CATCGACTGT GTGGCCATCC TGCCCTTCTA TCTCGAGGTG 
GGCCTCTCGG GCCTCAGCTC CAAGGCCGCC AAAGACGTGC TGGGCTTCCT GCGGGTGGTC 
CGCTTCGTCC GCATCCTGCG CATCTTCAAG CTGACCCGGC ACTTCGTGGG GCTGCGCGTG 
CTGGGACACA CGCTCCGCGC CAGCACCAAC GAGTTCCTGC TGCTCATCAT CTTCCTGGCC 
CTGGGGGTGC TCATCTTCGC CACCATGATT TACTACGCTG AGCGCATTGG CGCCGACCCC 
GATGACATCC TGGGCTCCAA CCACACCTAC TTCAAGAACA TCCCCATTGG CTTCTGGTGG 
GCTGTGGTCA CCATGACGAC CCTGGGCTAT GGAGACATGT ACCCCAAGAC GTGGTCGGGG 
ATGCTGGTCG GGGCGCTGTG TGCCCTGGCG GGGGTGCTGA CCATCGCCAT GCCTGTGCCC 
GTCATTGTCA ACAACTTTGG CATGTACTAT TCGCTGGCCA TGGCCAAGCA GAAGCTGCCC 
AAGAAGAAGA ACAAACACAT CCCCCGGCCC CCGCAACCGG GCTCGCCCAA CTACTGCAAG 
CCTGACCCAC CCCCGCCACC CCCGCCCCAC CCGCACCACG GCAGCGGGGG CATCAGCCCG 
CCGCCACCCA TCACCCCACC CTCCATGGGG GTGACTGTGG CCGGGGCCTA CCCAGCGGGG 
CCCCACACGC ACCCCGGGCT GCTCAGGGGG GGAGCGGGTG GGCTGGGGAT CATGGGGCTG 
CCTCCTCTGC CAGCCCCCGG CGAGCCTTGC CCGTTGGCTC AGGAGGAGGT GATTGAGATC 
AACCGGGCAG ATCCTCGCCC CAATGGGGAT CCGGCAGCAG CTGCGCTTGC CCACGAGGAC 
TGCCCAGCCA TTGACCAGCC TGCCATGTCC CCGGAAGACA AGAGCCCCAT CACGCCTGGA 
AGCCGTGGCC GCTATAGCCG GGACCGAGCC TGCTTCCTCC TCACCGACTA TGCCCCTTCC 
CCTGATGGCT CCATCCGAAA AGCCACTGGT GCTCCCCCAC TGCCCCCCCA AGACTGGCGT 
AAGCCAGGCC CCCCAAGCTT CTTGCCCGAC CTCAACGCCA ACGCCGCGGC CTGGATATCC 
CCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KCNC3 ( NM_004977.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_004968.2 Homo sapiens potassium voltage-gated channel subfamily C member 3 (KCNC3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu25796
Clone ID Related Accession (Same CDS sequence)	NM_004977.2 , XM_011526926.1 , XM_006723203.2 , NM_004977.3
Accession Version	NM_004977.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2274bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Homo sapiens(human)
Product	potassium voltage-gated channel subfamily C member 3 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF055989.1 and AC008655.7. This sequence is a reference standard in the RefSeqGene project. On Aug 29, 2019 this sequence version replaced NM_004977.2. Transcript Variant: This variant (1) encodes isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF055989.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, expression, longest protein ##RefSeq-Attributes-END##

ATGCTGAGCT CAGTCTGCGT CTCGTCCTTC CGCGGGCGCC AGGGGGCCAG CAAGCAGCAG 
CCGGCGCCAC CGCCGCAGCC GCCCGAGTCC CCGCCGCCGC CACCGCTGCC GCCGCAGCAG 
CAGCAGCCTG CGCAGCCCGG CCCCGCCGCG TCCCCGGCGG GCCCCCCGGC ACCCCGCGGG 
CCCGGGGACC GGCGCGCCGA GCCATGCCCC GGGCTGCCGG CGGCGGCCAT GGGGCGGCAC 
GGCGGCGGCG GTGGCGACAG CGGCAAGATC GTGATCAACG TGGGCGGCGT GCGCCATGAG 
ACGTACCGCT CGACGCTGCG CACCCTGCCG GGGACGCGGC TGGCCGGCCT GACGGAGCCC 
GAGGCGGCGG CACGCTTCGA CTACGACCCG GGCGCCGACG AGTTCTTCTT TGACCGGCAC 
CCGGGAGTCT TCGCGTACGT GCTCAACTAC TACCGCACCG GCAAGCTGCA CTGCCCAGCC 
GACGTGTGCG GGCCCCTGTT TGAGGAGGAG CTCGGCTTCT GGGGCATCGA CGAGACCGAC 
GTGGAGGCCT GCTGCTGGAT GACCTACCGG CAGCATCGCG ACGCTGAGGA GGCGCTCGAC 
TCCTTCGAGG CGCCCGACCC CGCGGGCGCC GCCAACGCCG CCAACGCCGC AGGCGCCCAC 
GACGGAGGCC TGGACGACGA GGCGGGCGCG GGCGGCGGCG GCCTGGACGG AGCGGGCGGC 
GAGCTCAAGC GCCTCTGCTT CCAGGACGCG GGCGGCGGCG CCGGGGGGCC GCCAGGGGGC 
GCGGGCGGCG CGGGCGGCAC ATGGTGGCGC CGCTGGCAGC CCCGCGTGTG GGCGCTCTTC 
GAGGACCCCT ACTCGTCGCG GGCTGCCAGG TATGTGGCCT TCGCCTCCCT CTTCTTCATC 
CTCATCTCCA TCACCACCTT CTGCCTGGAA ACCCATGAGG GCTTCATCCA TATTAGCAAC 
AAGACGGTGA CCCAGGCCTC CCCGATCCCC GGGGCACCTC CGGAGAACAT CACCAACGTG 
GAGGTGGAGA CGGAGCCCTT CCTGACCTAC GTGGAGGGGG TGTGCGTGGT CTGGTTCACC 
TTCGAGTTCC TCATGCGCAT CACCTTCTGC CCAGACAAGG TGGAGTTTCT TAAAAGCAGC 
CTCAACATCA TCGACTGTGT GGCCATCCTG CCCTTCTATC TCGAGGTGGG CCTCTCGGGC 
CTCAGCTCCA AGGCCGCCAA AGACGTGCTG GGCTTCCTGC GGGTGGTCCG CTTCGTCCGC 
ATCCTGCGCA TCTTCAAGCT GACCCGGCAC TTCGTGGGGC TGCGCGTGCT GGGACACACG 
CTCCGCGCCA GCACCAACGA GTTCCTGCTG CTCATCATCT TCCTGGCCCT GGGGGTGCTC 
ATCTTCGCCA CCATGATTTA CTACGCTGAG CGCATTGGCG CCGACCCCGA TGACATCCTG 
GGCTCCAACC ACACCTACTT CAAGAACATC CCCATTGGCT TCTGGTGGGC TGTGGTCACC 
ATGACGACCC TGGGCTATGG AGACATGTAC CCCAAGACGT GGTCGGGGAT GCTGGTCGGG 
GCGCTGTGTG CCCTGGCGGG GGTGCTGACC ATCGCCATGC CTGTGCCCGT CATTGTCAAC 
AACTTTGGCA TGTACTATTC GCTGGCCATG GCCAAGCAGA AGCTGCCCAA GAAGAAGAAC 
AAACACATCC CCCGGCCCCC GCAACCGGGC TCGCCCAACT ACTGCAAGCC TGACCCACCC 
CCGCCACCCC CGCCCCACCC GCACCACGGC AGCGGGGGCA TCAGCCCGCC GCCACCCATC 
ACCCCACCCT CCATGGGGGT GACTGTGGCC GGGGCCTACC CAGCGGGGCC CCACACGCAC 
CCCGGGCTGC TCAGGGGGGG AGCGGGTGGG CTGGGGATCA TGGGGCTGCC TCCTCTGCCA 
GCCCCCGGCG AGCCTTGCCC GTTGGCTCAG GAGGAGGTGA TTGAGATCAA CCGGGCAGAT 
CCTCGCCCCA ATGGGGATCC GGCAGCAGCT GCGCTTGCCC ACGAGGACTG CCCAGCCATT 
GACCAGCCTG CCATGTCCCC GGAAGACAAG AGCCCCATCA CGCCTGGAAG CCGTGGCCGC 
TATAGCCGGG ACCGAGCCTG CTTCCTCCTC ACCGACTATG CCCCTTCCCC TGATGGCTCC 
ATCCGAAAAG CCACTGGTGC TCCCCCACTG CCCCCCCAAG ACTGGCGTAA GCCAGGCCCC 
CCAAGCTTCT TGCCCGACCT CAACGCCAAC GCCGCGGCCT GGATATCCCC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004968.2
CDS	296..2569
Translation	MLSSVCVSSFRGRQGASKQQPAPPPQPPESPPPPPLPPQQQQPAQPGPAASPAGPPAPRGPGDRRAEPCPGLPAAAMGRHGGGGGDSGKIVINVGGVRHETYRSTLRTLPGTRLAGLTEPEAAARFDYDPGADEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELGFWGIDETDVEACCWMTYRQHRDAEEALDSFEAPDPAGAANAANAAGAHDGGLDDEAGAGGGGLDGAGGELKRLCFQDAGGGAGGPPGGAGGAGGTWWRRWQPRVWALFEDPYSSRAARYVAFASLFFILISITTFCLETHEGFIHISNKTVTQASPIPGAPPENITNVEVETEPFLTYVEGVCVVWFTFEFLMRITFCPDKVEFLKSSLNIIDCVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDILGSNHTYFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIPRPPQPGSPNYCKPDPPPPPPPHPHHGSGGISPPPPITPPSMGVTVAGAYPAGPHTHPGLLRGGAGGLGIMGLPPLPAPGEPCPLAQEEVIEINRADPRPNGDPAAAALAHEDCPAIDQPAMSPEDKSPITPGSRGRYSRDRACFLLTDYAPSPDGSIRKATGAPPLPPQDWRKPGPPSFLPDLNANAAAWISP

Target ORF information:

RefSeq Version	NM_004977.3
Organism	Homo sapiens(human)
Definition	Homo sapiens potassium voltage-gated channel subfamily C member 3 (KCNC3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004977.3

ORF Insert Sequence:

ATGCTGAGCT CAGTCTGCGT CTCGTCCTTC CGCGGGCGCC AGGGGGCCAG CAAGCAGCAG 
CCGGCGCCAC CGCCGCAGCC GCCCGAGTCC CCGCCGCCGC CACCGCTGCC GCCGCAGCAG 
CAGCAGCCTG CGCAGCCCGG CCCCGCCGCG TCCCCGGCGG GCCCCCCGGC ACCCCGCGGG 
CCCGGGGACC GGCGCGCCGA GCCATGCCCC GGGCTGCCGG CGGCGGCCAT GGGGCGGCAC 
GGCGGCGGCG GTGGCGACAG CGGCAAGATC GTGATCAACG TGGGCGGCGT GCGCCATGAG 
ACGTACCGCT CGACGCTGCG CACCCTGCCG GGGACGCGGC TGGCCGGCCT GACGGAGCCC 
GAGGCGGCGG CACGCTTCGA CTACGACCCG GGCGCCGACG AGTTCTTCTT TGACCGGCAC 
CCGGGAGTCT TCGCGTACGT GCTCAACTAC TACCGCACCG GCAAGCTGCA CTGCCCAGCC 
GACGTGTGCG GGCCCCTGTT TGAGGAGGAG CTCGGCTTCT GGGGCATCGA CGAGACCGAC 
GTGGAGGCCT GCTGCTGGAT GACCTACCGG CAGCATCGCG ACGCTGAGGA GGCGCTCGAC 
TCCTTCGAGG CGCCCGACCC CGCGGGCGCC GCCAACGCCG CCAACGCCGC AGGCGCCCAC 
GACGGAGGCC TGGACGACGA GGCGGGCGCG GGCGGCGGCG GCCTGGACGG AGCGGGCGGC 
GAGCTCAAGC GCCTCTGCTT CCAGGACGCG GGCGGCGGCG CCGGGGGGCC GCCAGGGGGC 
GCGGGCGGCG CGGGCGGCAC ATGGTGGCGC CGCTGGCAGC CCCGCGTGTG GGCGCTCTTC 
GAGGACCCCT ACTCGTCGCG GGCTGCCAGG TATGTGGCCT TCGCCTCCCT CTTCTTCATC 
CTCATCTCCA TCACCACCTT CTGCCTGGAA ACCCATGAGG GCTTCATCCA TATTAGCAAC 
AAGACGGTGA CCCAGGCCTC CCCGATCCCC GGGGCACCTC CGGAGAACAT CACCAACGTG 
GAGGTGGAGA CGGAGCCCTT CCTGACCTAC GTGGAGGGGG TGTGCGTGGT CTGGTTCACC 
TTCGAGTTCC TCATGCGCAT CACCTTCTGC CCAGACAAGG TGGAGTTTCT TAAAAGCAGC 
CTCAACATCA TCGACTGTGT GGCCATCCTG CCCTTCTATC TCGAGGTGGG CCTCTCGGGC 
CTCAGCTCCA AGGCCGCCAA AGACGTGCTG GGCTTCCTGC GGGTGGTCCG CTTCGTCCGC 
ATCCTGCGCA TCTTCAAGCT GACCCGGCAC TTCGTGGGGC TGCGCGTGCT GGGACACACG 
CTCCGCGCCA GCACCAACGA GTTCCTGCTG CTCATCATCT TCCTGGCCCT GGGGGTGCTC 
ATCTTCGCCA CCATGATTTA CTACGCTGAG CGCATTGGCG CCGACCCCGA TGACATCCTG 
GGCTCCAACC ACACCTACTT CAAGAACATC CCCATTGGCT TCTGGTGGGC TGTGGTCACC 
ATGACGACCC TGGGCTATGG AGACATGTAC CCCAAGACGT GGTCGGGGAT GCTGGTCGGG 
GCGCTGTGTG CCCTGGCGGG GGTGCTGACC ATCGCCATGC CTGTGCCCGT CATTGTCAAC 
AACTTTGGCA TGTACTATTC GCTGGCCATG GCCAAGCAGA AGCTGCCCAA GAAGAAGAAC 
AAACACATCC CCCGGCCCCC GCAACCGGGC TCGCCCAACT ACTGCAAGCC TGACCCACCC 
CCGCCACCCC CGCCCCACCC GCACCACGGC AGCGGGGGCA TCAGCCCGCC GCCACCCATC 
ACCCCACCCT CCATGGGGGT GACTGTGGCC GGGGCCTACC CAGCGGGGCC CCACACGCAC 
CCCGGGCTGC TCAGGGGGGG AGCGGGTGGG CTGGGGATCA TGGGGCTGCC TCCTCTGCCA 
GCCCCCGGCG AGCCTTGCCC GTTGGCTCAG GAGGAGGTGA TTGAGATCAA CCGGGCAGAT 
CCTCGCCCCA ATGGGGATCC GGCAGCAGCT GCGCTTGCCC ACGAGGACTG CCCAGCCATT 
GACCAGCCTG CCATGTCCCC GGAAGACAAG AGCCCCATCA CGCCTGGAAG CCGTGGCCGC 
TATAGCCGGG ACCGAGCCTG CTTCCTCCTC ACCGACTATG CCCCTTCCCC TGATGGCTCC 
ATCCGAAAAG CCACTGGTGC TCCCCCACTG CCCCCCCAAG ACTGGCGTAA GCCAGGCCCC 
CCAAGCTTCT TGCCCGACCT CAACGCCAAC GCCGCGGCCT GGATATCCCC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KCNC3 ( NM_004977.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_004968.2 Homo sapiens potassium voltage-gated channel subfamily C member 3 (KCNC3), transcript variant 1, mRNA.

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CloneID	OHu25796
Clone ID Related Accession (Same CDS sequence)	NM_004977.2 , XM_011526926.1 , XM_006723203.2 , NM_004977.3
Accession Version	NM_004977.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2274bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-03
Organism	Homo sapiens(human)
Product	potassium voltage-gated channel subfamily C member 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF055989.1. This sequence is a reference standard in the RefSeqGene project. On Nov 3, 2002 this sequence version replaced NM_004977.1. Transcript Variant: This variant (1) represents the shorter transcript and encodes the protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF055989.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGCTGAGCT CAGTCTGCGT CTCGTCCTTC CGCGGGCGCC AGGGGGCCAG CAAGCAGCAG 
CCGGCGCCAC CGCCGCAGCC GCCCGAGTCC CCGCCGCCGC CACCGCTGCC GCCGCAGCAG 
CAGCAGCCTG CGCAGCCCGG CCCCGCCGCG TCCCCGGCGG GCCCCCCGGC ACCCCGCGGG 
CCCGGGGACC GGCGCGCCGA GCCATGCCCC GGGCTGCCGG CGGCGGCCAT GGGGCGGCAC 
GGCGGCGGCG GTGGCGACAG CGGCAAGATC GTGATCAACG TGGGCGGCGT GCGCCATGAG 
ACGTACCGCT CGACGCTGCG CACCCTGCCG GGGACGCGGC TGGCCGGCCT GACGGAGCCC 
GAGGCGGCGG CACGCTTCGA CTACGACCCG GGCGCCGACG AGTTCTTCTT TGACCGGCAC 
CCGGGAGTCT TCGCGTACGT GCTCAACTAC TACCGCACCG GCAAGCTGCA CTGCCCAGCC 
GACGTGTGCG GGCCCCTGTT TGAGGAGGAG CTCGGCTTCT GGGGCATCGA CGAGACCGAC 
GTGGAGGCCT GCTGCTGGAT GACCTACCGG CAGCATCGCG ACGCTGAGGA GGCGCTCGAC 
TCCTTCGAGG CGCCCGACCC CGCGGGCGCC GCCAACGCCG CCAACGCCGC AGGCGCCCAC 
GACGGAGGCC TGGACGACGA GGCGGGCGCG GGCGGCGGCG GCCTGGACGG AGCGGGCGGC 
GAGCTCAAGC GCCTCTGCTT CCAGGACGCG GGCGGCGGCG CCGGGGGGCC GCCAGGGGGC 
GCGGGCGGCG CGGGCGGCAC ATGGTGGCGC CGCTGGCAGC CCCGCGTGTG GGCGCTCTTC 
GAGGACCCCT ACTCGTCGCG GGCTGCCAGG TATGTGGCCT TCGCCTCCCT CTTCTTCATC 
CTCATCTCCA TCACCACCTT CTGCCTGGAA ACCCATGAGG GCTTCATCCA TATTAGCAAC 
AAGACGGTGA CCCAGGCCTC CCCGATCCCC GGGGCACCTC CGGAGAACAT CACCAACGTG 
GAGGTGGAGA CGGAGCCCTT CCTGACCTAC GTGGAGGGGG TGTGCGTGGT CTGGTTCACC 
TTCGAGTTCC TCATGCGCAT CACCTTCTGC CCAGACAAGG TGGAGTTTCT TAAAAGCAGC 
CTCAACATCA TCGACTGTGT GGCCATCCTG CCCTTCTATC TCGAGGTGGG CCTCTCGGGC 
CTCAGCTCCA AGGCCGCCAA AGACGTGCTG GGCTTCCTGC GGGTGGTCCG CTTCGTCCGC 
ATCCTGCGCA TCTTCAAGCT GACCCGGCAC TTCGTGGGGC TGCGCGTGCT GGGACACACG 
CTCCGCGCCA GCACCAACGA GTTCCTGCTG CTCATCATCT TCCTGGCCCT GGGGGTGCTC 
ATCTTCGCCA CCATGATTTA CTACGCTGAG CGCATTGGCG CCGACCCCGA TGACATCCTG 
GGCTCCAACC ACACCTACTT CAAGAACATC CCCATTGGCT TCTGGTGGGC TGTGGTCACC 
ATGACGACCC TGGGCTATGG AGACATGTAC CCCAAGACGT GGTCGGGGAT GCTGGTCGGG 
GCGCTGTGTG CCCTGGCGGG GGTGCTGACC ATCGCCATGC CTGTGCCCGT CATTGTCAAC 
AACTTTGGCA TGTACTATTC GCTGGCCATG GCCAAGCAGA AGCTGCCCAA GAAGAAGAAC 
AAACACATCC CCCGGCCCCC GCAACCGGGC TCGCCCAACT ACTGCAAGCC TGACCCACCC 
CCGCCACCCC CGCCCCACCC GCACCACGGC AGCGGGGGCA TCAGCCCGCC GCCACCCATC 
ACCCCACCCT CCATGGGGGT GACTGTGGCC GGGGCCTACC CAGCGGGGCC CCACACGCAC 
CCCGGGCTGC TCAGGGGGGG AGCGGGTGGG CTGGGGATCA TGGGGCTGCC TCCTCTGCCA 
GCCCCCGGCG AGCCTTGCCC GTTGGCTCAG GAGGAGGTGA TTGAGATCAA CCGGGCAGAT 
CCTCGCCCCA ATGGGGATCC GGCAGCAGCT GCGCTTGCCC ACGAGGACTG CCCAGCCATT 
GACCAGCCTG CCATGTCCCC GGAAGACAAG AGCCCCATCA CGCCTGGAAG CCGTGGCCGC 
TATAGCCGGG ACCGAGCCTG CTTCCTCCTC ACCGACTATG CCCCTTCCCC TGATGGCTCC 
ATCCGAAAAG CCACTGGTGC TCCCCCACTG CCCCCCCAAG ACTGGCGTAA GCCAGGCCCC 
CCAAGCTTCT TGCCCGACCT CAACGCCAAC GCCGCGGCCT GGATATCCCC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004968.2
CDS	296..2569
Translation	MLSSVCVSSFRGRQGASKQQPAPPPQPPESPPPPPLPPQQQQPAQPGPAASPAGPPAPRGPGDRRAEPCPGLPAAAMGRHGGGGGDSGKIVINVGGVRHETYRSTLRTLPGTRLAGLTEPEAAARFDYDPGADEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELGFWGIDETDVEACCWMTYRQHRDAEEALDSFEAPDPAGAANAANAAGAHDGGLDDEAGAGGGGLDGAGGELKRLCFQDAGGGAGGPPGGAGGAGGTWWRRWQPRVWALFEDPYSSRAARYVAFASLFFILISITTFCLETHEGFIHISNKTVTQASPIPGAPPENITNVEVETEPFLTYVEGVCVVWFTFEFLMRITFCPDKVEFLKSSLNIIDCVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDILGSNHTYFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIPRPPQPGSPNYCKPDPPPPPPPHPHHGSGGISPPPPITPPSMGVTVAGAYPAGPHTHPGLLRGGAGGLGIMGLPPLPAPGEPCPLAQEEVIEINRADPRPNGDPAAAALAHEDCPAIDQPAMSPEDKSPITPGSRGRYSRDRACFLLTDYAPSPDGSIRKATGAPPLPPQDWRKPGPPSFLPDLNANAAAWISP

Target ORF information:

RefSeq Version	NM_004977.2
Organism	Homo sapiens(human)
Definition	Homo sapiens potassium voltage-gated channel subfamily C member 3 (KCNC3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004977.2

ORF Insert Sequence:

ATGCTGAGCT CAGTCTGCGT CTCGTCCTTC CGCGGGCGCC AGGGGGCCAG CAAGCAGCAG 
CCGGCGCCAC CGCCGCAGCC GCCCGAGTCC CCGCCGCCGC CACCGCTGCC GCCGCAGCAG 
CAGCAGCCTG CGCAGCCCGG CCCCGCCGCG TCCCCGGCGG GCCCCCCGGC ACCCCGCGGG 
CCCGGGGACC GGCGCGCCGA GCCATGCCCC GGGCTGCCGG CGGCGGCCAT GGGGCGGCAC 
GGCGGCGGCG GTGGCGACAG CGGCAAGATC GTGATCAACG TGGGCGGCGT GCGCCATGAG 
ACGTACCGCT CGACGCTGCG CACCCTGCCG GGGACGCGGC TGGCCGGCCT GACGGAGCCC 
GAGGCGGCGG CACGCTTCGA CTACGACCCG GGCGCCGACG AGTTCTTCTT TGACCGGCAC 
CCGGGAGTCT TCGCGTACGT GCTCAACTAC TACCGCACCG GCAAGCTGCA CTGCCCAGCC 
GACGTGTGCG GGCCCCTGTT TGAGGAGGAG CTCGGCTTCT GGGGCATCGA CGAGACCGAC 
GTGGAGGCCT GCTGCTGGAT GACCTACCGG CAGCATCGCG ACGCTGAGGA GGCGCTCGAC 
TCCTTCGAGG CGCCCGACCC CGCGGGCGCC GCCAACGCCG CCAACGCCGC AGGCGCCCAC 
GACGGAGGCC TGGACGACGA GGCGGGCGCG GGCGGCGGCG GCCTGGACGG AGCGGGCGGC 
GAGCTCAAGC GCCTCTGCTT CCAGGACGCG GGCGGCGGCG CCGGGGGGCC GCCAGGGGGC 
GCGGGCGGCG CGGGCGGCAC ATGGTGGCGC CGCTGGCAGC CCCGCGTGTG GGCGCTCTTC 
GAGGACCCCT ACTCGTCGCG GGCTGCCAGG TATGTGGCCT TCGCCTCCCT CTTCTTCATC 
CTCATCTCCA TCACCACCTT CTGCCTGGAA ACCCATGAGG GCTTCATCCA TATTAGCAAC 
AAGACGGTGA CCCAGGCCTC CCCGATCCCC GGGGCACCTC CGGAGAACAT CACCAACGTG 
GAGGTGGAGA CGGAGCCCTT CCTGACCTAC GTGGAGGGGG TGTGCGTGGT CTGGTTCACC 
TTCGAGTTCC TCATGCGCAT CACCTTCTGC CCAGACAAGG TGGAGTTTCT TAAAAGCAGC 
CTCAACATCA TCGACTGTGT GGCCATCCTG CCCTTCTATC TCGAGGTGGG CCTCTCGGGC 
CTCAGCTCCA AGGCCGCCAA AGACGTGCTG GGCTTCCTGC GGGTGGTCCG CTTCGTCCGC 
ATCCTGCGCA TCTTCAAGCT GACCCGGCAC TTCGTGGGGC TGCGCGTGCT GGGACACACG 
CTCCGCGCCA GCACCAACGA GTTCCTGCTG CTCATCATCT TCCTGGCCCT GGGGGTGCTC 
ATCTTCGCCA CCATGATTTA CTACGCTGAG CGCATTGGCG CCGACCCCGA TGACATCCTG 
GGCTCCAACC ACACCTACTT CAAGAACATC CCCATTGGCT TCTGGTGGGC TGTGGTCACC 
ATGACGACCC TGGGCTATGG AGACATGTAC CCCAAGACGT GGTCGGGGAT GCTGGTCGGG 
GCGCTGTGTG CCCTGGCGGG GGTGCTGACC ATCGCCATGC CTGTGCCCGT CATTGTCAAC 
AACTTTGGCA TGTACTATTC GCTGGCCATG GCCAAGCAGA AGCTGCCCAA GAAGAAGAAC 
AAACACATCC CCCGGCCCCC GCAACCGGGC TCGCCCAACT ACTGCAAGCC TGACCCACCC 
CCGCCACCCC CGCCCCACCC GCACCACGGC AGCGGGGGCA TCAGCCCGCC GCCACCCATC 
ACCCCACCCT CCATGGGGGT GACTGTGGCC GGGGCCTACC CAGCGGGGCC CCACACGCAC 
CCCGGGCTGC TCAGGGGGGG AGCGGGTGGG CTGGGGATCA TGGGGCTGCC TCCTCTGCCA 
GCCCCCGGCG AGCCTTGCCC GTTGGCTCAG GAGGAGGTGA TTGAGATCAA CCGGGCAGAT 
CCTCGCCCCA ATGGGGATCC GGCAGCAGCT GCGCTTGCCC ACGAGGACTG CCCAGCCATT 
GACCAGCCTG CCATGTCCCC GGAAGACAAG AGCCCCATCA CGCCTGGAAG CCGTGGCCGC 
TATAGCCGGG ACCGAGCCTG CTTCCTCCTC ACCGACTATG CCCCTTCCCC TGATGGCTCC 
ATCCGAAAAG CCACTGGTGC TCCCCCACTG CCCCCCCAAG ACTGGCGTAA GCCAGGCCCC 
CCAAGCTTCT TGCCCGACCT CAACGCCAAC GCCGCGGCCT GGATATCCCC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KCNC3 ( XM_011526926.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011525228.1 Homo sapiens potassium voltage-gated channel subfamily C member 3 (KCNC3), transcript variant X1, mRNA.

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CloneID	OHu25796
Clone ID Related Accession (Same CDS sequence)	NM_004977.2 , XM_011526926.1 , XM_006723203.2 , NM_004977.3
Accession Version	XM_011526926.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2274bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	potassium voltage-gated channel subfamily C member 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGAGCT CAGTCTGCGT CTCGTCCTTC CGCGGGCGCC AGGGGGCCAG CAAGCAGCAG 
CCGGCGCCAC CGCCGCAGCC GCCCGAGTCC CCGCCGCCGC CACCGCTGCC GCCGCAGCAG 
CAGCAGCCTG CGCAGCCCGG CCCCGCCGCG TCCCCGGCGG GCCCCCCGGC ACCCCGCGGG 
CCCGGGGACC GGCGCGCCGA GCCATGCCCC GGGCTGCCGG CGGCGGCCAT GGGGCGGCAC 
GGCGGCGGCG GTGGCGACAG CGGCAAGATC GTGATCAACG TGGGCGGCGT GCGCCATGAG 
ACGTACCGCT CGACGCTGCG CACCCTGCCG GGGACGCGGC TGGCCGGCCT GACGGAGCCC 
GAGGCGGCGG CACGCTTCGA CTACGACCCG GGCGCCGACG AGTTCTTCTT TGACCGGCAC 
CCGGGAGTCT TCGCGTACGT GCTCAACTAC TACCGCACCG GCAAGCTGCA CTGCCCAGCC 
GACGTGTGCG GGCCCCTGTT TGAGGAGGAG CTCGGCTTCT GGGGCATCGA CGAGACCGAC 
GTGGAGGCCT GCTGCTGGAT GACCTACCGG CAGCATCGCG ACGCTGAGGA GGCGCTCGAC 
TCCTTCGAGG CGCCCGACCC CGCGGGCGCC GCCAACGCCG CCAACGCCGC AGGCGCCCAC 
GACGGAGGCC TGGACGACGA GGCGGGCGCG GGCGGCGGCG GCCTGGACGG AGCGGGCGGC 
GAGCTCAAGC GCCTCTGCTT CCAGGACGCG GGCGGCGGCG CCGGGGGGCC GCCAGGGGGC 
GCGGGCGGCG CGGGCGGCAC ATGGTGGCGC CGCTGGCAGC CCCGCGTGTG GGCGCTCTTC 
GAGGACCCCT ACTCGTCGCG GGCTGCCAGG TATGTGGCCT TCGCCTCCCT CTTCTTCATC 
CTCATCTCCA TCACCACCTT CTGCCTGGAA ACCCATGAGG GCTTCATCCA TATTAGCAAC 
AAGACGGTGA CCCAGGCCTC CCCGATCCCC GGGGCACCTC CGGAGAACAT CACCAACGTG 
GAGGTGGAGA CGGAGCCCTT CCTGACCTAC GTGGAGGGGG TGTGCGTGGT CTGGTTCACC 
TTCGAGTTCC TCATGCGCAT CACCTTCTGC CCAGACAAGG TGGAGTTTCT TAAAAGCAGC 
CTCAACATCA TCGACTGTGT GGCCATCCTG CCCTTCTATC TCGAGGTGGG CCTCTCGGGC 
CTCAGCTCCA AGGCCGCCAA AGACGTGCTG GGCTTCCTGC GGGTGGTCCG CTTCGTCCGC 
ATCCTGCGCA TCTTCAAGCT GACCCGGCAC TTCGTGGGGC TGCGCGTGCT GGGACACACG 
CTCCGCGCCA GCACCAACGA GTTCCTGCTG CTCATCATCT TCCTGGCCCT GGGGGTGCTC 
ATCTTCGCCA CCATGATTTA CTACGCTGAG CGCATTGGCG CCGACCCCGA TGACATCCTG 
GGCTCCAACC ACACCTACTT CAAGAACATC CCCATTGGCT TCTGGTGGGC TGTGGTCACC 
ATGACGACCC TGGGCTATGG AGACATGTAC CCCAAGACGT GGTCGGGGAT GCTGGTCGGG 
GCGCTGTGTG CCCTGGCGGG GGTGCTGACC ATCGCCATGC CTGTGCCCGT CATTGTCAAC 
AACTTTGGCA TGTACTATTC GCTGGCCATG GCCAAGCAGA AGCTGCCCAA GAAGAAGAAC 
AAACACATCC CCCGGCCCCC GCAACCGGGC TCGCCCAACT ACTGCAAGCC TGACCCACCC 
CCGCCACCCC CGCCCCACCC GCACCACGGC AGCGGGGGCA TCAGCCCGCC GCCACCCATC 
ACCCCACCCT CCATGGGGGT GACTGTGGCC GGGGCCTACC CAGCGGGGCC CCACACGCAC 
CCCGGGCTGC TCAGGGGGGG AGCGGGTGGG CTGGGGATCA TGGGGCTGCC TCCTCTGCCA 
GCCCCCGGCG AGCCTTGCCC GTTGGCTCAG GAGGAGGTGA TTGAGATCAA CCGGGCAGAT 
CCTCGCCCCA ATGGGGATCC GGCAGCAGCT GCGCTTGCCC ACGAGGACTG CCCAGCCATT 
GACCAGCCTG CCATGTCCCC GGAAGACAAG AGCCCCATCA CGCCTGGAAG CCGTGGCCGC 
TATAGCCGGG ACCGAGCCTG CTTCCTCCTC ACCGACTATG CCCCTTCCCC TGATGGCTCC 
ATCCGAAAAG CCACTGGTGC TCCCCCACTG CCCCCCCAAG ACTGGCGTAA GCCAGGCCCC 
CCAAGCTTCT TGCCCGACCT CAACGCCAAC GCCGCGGCCT GGATATCCCC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011525228.1
CDS	1..2274
Translation	MLSSVCVSSFRGRQGASKQQPAPPPQPPESPPPPPLPPQQQQPAQPGPAASPAGPPAPRGPGDRRAEPCPGLPAAAMGRHGGGGGDSGKIVINVGGVRHETYRSTLRTLPGTRLAGLTEPEAAARFDYDPGADEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELGFWGIDETDVEACCWMTYRQHRDAEEALDSFEAPDPAGAANAANAAGAHDGGLDDEAGAGGGGLDGAGGELKRLCFQDAGGGAGGPPGGAGGAGGTWWRRWQPRVWALFEDPYSSRAARYVAFASLFFILISITTFCLETHEGFIHISNKTVTQASPIPGAPPENITNVEVETEPFLTYVEGVCVVWFTFEFLMRITFCPDKVEFLKSSLNIIDCVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDILGSNHTYFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIPRPPQPGSPNYCKPDPPPPPPPHPHHGSGGISPPPPITPPSMGVTVAGAYPAGPHTHPGLLRGGAGGLGIMGLPPLPAPGEPCPLAQEEVIEINRADPRPNGDPAAAALAHEDCPAIDQPAMSPEDKSPITPGSRGRYSRDRACFLLTDYAPSPDGSIRKATGAPPLPPQDWRKPGPPSFLPDLNANAAAWISP

Target ORF information:

RefSeq Version	XM_011526926.1
Organism	Homo sapiens(human)
Definition	Homo sapiens potassium voltage-gated channel subfamily C member 3 (KCNC3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011526926.1

ORF Insert Sequence:

ATGCTGAGCT CAGTCTGCGT CTCGTCCTTC CGCGGGCGCC AGGGGGCCAG CAAGCAGCAG 
CCGGCGCCAC CGCCGCAGCC GCCCGAGTCC CCGCCGCCGC CACCGCTGCC GCCGCAGCAG 
CAGCAGCCTG CGCAGCCCGG CCCCGCCGCG TCCCCGGCGG GCCCCCCGGC ACCCCGCGGG 
CCCGGGGACC GGCGCGCCGA GCCATGCCCC GGGCTGCCGG CGGCGGCCAT GGGGCGGCAC 
GGCGGCGGCG GTGGCGACAG CGGCAAGATC GTGATCAACG TGGGCGGCGT GCGCCATGAG 
ACGTACCGCT CGACGCTGCG CACCCTGCCG GGGACGCGGC TGGCCGGCCT GACGGAGCCC 
GAGGCGGCGG CACGCTTCGA CTACGACCCG GGCGCCGACG AGTTCTTCTT TGACCGGCAC 
CCGGGAGTCT TCGCGTACGT GCTCAACTAC TACCGCACCG GCAAGCTGCA CTGCCCAGCC 
GACGTGTGCG GGCCCCTGTT TGAGGAGGAG CTCGGCTTCT GGGGCATCGA CGAGACCGAC 
GTGGAGGCCT GCTGCTGGAT GACCTACCGG CAGCATCGCG ACGCTGAGGA GGCGCTCGAC 
TCCTTCGAGG CGCCCGACCC CGCGGGCGCC GCCAACGCCG CCAACGCCGC AGGCGCCCAC 
GACGGAGGCC TGGACGACGA GGCGGGCGCG GGCGGCGGCG GCCTGGACGG AGCGGGCGGC 
GAGCTCAAGC GCCTCTGCTT CCAGGACGCG GGCGGCGGCG CCGGGGGGCC GCCAGGGGGC 
GCGGGCGGCG CGGGCGGCAC ATGGTGGCGC CGCTGGCAGC CCCGCGTGTG GGCGCTCTTC 
GAGGACCCCT ACTCGTCGCG GGCTGCCAGG TATGTGGCCT TCGCCTCCCT CTTCTTCATC 
CTCATCTCCA TCACCACCTT CTGCCTGGAA ACCCATGAGG GCTTCATCCA TATTAGCAAC 
AAGACGGTGA CCCAGGCCTC CCCGATCCCC GGGGCACCTC CGGAGAACAT CACCAACGTG 
GAGGTGGAGA CGGAGCCCTT CCTGACCTAC GTGGAGGGGG TGTGCGTGGT CTGGTTCACC 
TTCGAGTTCC TCATGCGCAT CACCTTCTGC CCAGACAAGG TGGAGTTTCT TAAAAGCAGC 
CTCAACATCA TCGACTGTGT GGCCATCCTG CCCTTCTATC TCGAGGTGGG CCTCTCGGGC 
CTCAGCTCCA AGGCCGCCAA AGACGTGCTG GGCTTCCTGC GGGTGGTCCG CTTCGTCCGC 
ATCCTGCGCA TCTTCAAGCT GACCCGGCAC TTCGTGGGGC TGCGCGTGCT GGGACACACG 
CTCCGCGCCA GCACCAACGA GTTCCTGCTG CTCATCATCT TCCTGGCCCT GGGGGTGCTC 
ATCTTCGCCA CCATGATTTA CTACGCTGAG CGCATTGGCG CCGACCCCGA TGACATCCTG 
GGCTCCAACC ACACCTACTT CAAGAACATC CCCATTGGCT TCTGGTGGGC TGTGGTCACC 
ATGACGACCC TGGGCTATGG AGACATGTAC CCCAAGACGT GGTCGGGGAT GCTGGTCGGG 
GCGCTGTGTG CCCTGGCGGG GGTGCTGACC ATCGCCATGC CTGTGCCCGT CATTGTCAAC 
AACTTTGGCA TGTACTATTC GCTGGCCATG GCCAAGCAGA AGCTGCCCAA GAAGAAGAAC 
AAACACATCC CCCGGCCCCC GCAACCGGGC TCGCCCAACT ACTGCAAGCC TGACCCACCC 
CCGCCACCCC CGCCCCACCC GCACCACGGC AGCGGGGGCA TCAGCCCGCC GCCACCCATC 
ACCCCACCCT CCATGGGGGT GACTGTGGCC GGGGCCTACC CAGCGGGGCC CCACACGCAC 
CCCGGGCTGC TCAGGGGGGG AGCGGGTGGG CTGGGGATCA TGGGGCTGCC TCCTCTGCCA 
GCCCCCGGCG AGCCTTGCCC GTTGGCTCAG GAGGAGGTGA TTGAGATCAA CCGGGCAGAT 
CCTCGCCCCA ATGGGGATCC GGCAGCAGCT GCGCTTGCCC ACGAGGACTG CCCAGCCATT 
GACCAGCCTG CCATGTCCCC GGAAGACAAG AGCCCCATCA CGCCTGGAAG CCGTGGCCGC 
TATAGCCGGG ACCGAGCCTG CTTCCTCCTC ACCGACTATG CCCCTTCCCC TGATGGCTCC 
ATCCGAAAAG CCACTGGTGC TCCCCCACTG CCCCCCCAAG ACTGGCGTAA GCCAGGCCCC 
CCAAGCTTCT TGCCCGACCT CAACGCCAAC GCCGCGGCCT GGATATCCCC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KCNC3 ( XM_006723203.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_006723266.1 Homo sapiens potassium voltage-gated channel subfamily C member 3 (KCNC3), transcript variant X2, mRNA.

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CloneID	OHu25796
Clone ID Related Accession (Same CDS sequence)	NM_004977.2 , XM_011526926.1 , XM_006723203.2 , NM_004977.3
Accession Version	XM_006723203.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2274bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	potassium voltage-gated channel subfamily C member 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced XM_006723203.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGAGCT CAGTCTGCGT CTCGTCCTTC CGCGGGCGCC AGGGGGCCAG CAAGCAGCAG 
CCGGCGCCAC CGCCGCAGCC GCCCGAGTCC CCGCCGCCGC CACCGCTGCC GCCGCAGCAG 
CAGCAGCCTG CGCAGCCCGG CCCCGCCGCG TCCCCGGCGG GCCCCCCGGC ACCCCGCGGG 
CCCGGGGACC GGCGCGCCGA GCCATGCCCC GGGCTGCCGG CGGCGGCCAT GGGGCGGCAC 
GGCGGCGGCG GTGGCGACAG CGGCAAGATC GTGATCAACG TGGGCGGCGT GCGCCATGAG 
ACGTACCGCT CGACGCTGCG CACCCTGCCG GGGACGCGGC TGGCCGGCCT GACGGAGCCC 
GAGGCGGCGG CACGCTTCGA CTACGACCCG GGCGCCGACG AGTTCTTCTT TGACCGGCAC 
CCGGGAGTCT TCGCGTACGT GCTCAACTAC TACCGCACCG GCAAGCTGCA CTGCCCAGCC 
GACGTGTGCG GGCCCCTGTT TGAGGAGGAG CTCGGCTTCT GGGGCATCGA CGAGACCGAC 
GTGGAGGCCT GCTGCTGGAT GACCTACCGG CAGCATCGCG ACGCTGAGGA GGCGCTCGAC 
TCCTTCGAGG CGCCCGACCC CGCGGGCGCC GCCAACGCCG CCAACGCCGC AGGCGCCCAC 
GACGGAGGCC TGGACGACGA GGCGGGCGCG GGCGGCGGCG GCCTGGACGG AGCGGGCGGC 
GAGCTCAAGC GCCTCTGCTT CCAGGACGCG GGCGGCGGCG CCGGGGGGCC GCCAGGGGGC 
GCGGGCGGCG CGGGCGGCAC ATGGTGGCGC CGCTGGCAGC CCCGCGTGTG GGCGCTCTTC 
GAGGACCCCT ACTCGTCGCG GGCTGCCAGG TATGTGGCCT TCGCCTCCCT CTTCTTCATC 
CTCATCTCCA TCACCACCTT CTGCCTGGAA ACCCATGAGG GCTTCATCCA TATTAGCAAC 
AAGACGGTGA CCCAGGCCTC CCCGATCCCC GGGGCACCTC CGGAGAACAT CACCAACGTG 
GAGGTGGAGA CGGAGCCCTT CCTGACCTAC GTGGAGGGGG TGTGCGTGGT CTGGTTCACC 
TTCGAGTTCC TCATGCGCAT CACCTTCTGC CCAGACAAGG TGGAGTTTCT TAAAAGCAGC 
CTCAACATCA TCGACTGTGT GGCCATCCTG CCCTTCTATC TCGAGGTGGG CCTCTCGGGC 
CTCAGCTCCA AGGCCGCCAA AGACGTGCTG GGCTTCCTGC GGGTGGTCCG CTTCGTCCGC 
ATCCTGCGCA TCTTCAAGCT GACCCGGCAC TTCGTGGGGC TGCGCGTGCT GGGACACACG 
CTCCGCGCCA GCACCAACGA GTTCCTGCTG CTCATCATCT TCCTGGCCCT GGGGGTGCTC 
ATCTTCGCCA CCATGATTTA CTACGCTGAG CGCATTGGCG CCGACCCCGA TGACATCCTG 
GGCTCCAACC ACACCTACTT CAAGAACATC CCCATTGGCT TCTGGTGGGC TGTGGTCACC 
ATGACGACCC TGGGCTATGG AGACATGTAC CCCAAGACGT GGTCGGGGAT GCTGGTCGGG 
GCGCTGTGTG CCCTGGCGGG GGTGCTGACC ATCGCCATGC CTGTGCCCGT CATTGTCAAC 
AACTTTGGCA TGTACTATTC GCTGGCCATG GCCAAGCAGA AGCTGCCCAA GAAGAAGAAC 
AAACACATCC CCCGGCCCCC GCAACCGGGC TCGCCCAACT ACTGCAAGCC TGACCCACCC 
CCGCCACCCC CGCCCCACCC GCACCACGGC AGCGGGGGCA TCAGCCCGCC GCCACCCATC 
ACCCCACCCT CCATGGGGGT GACTGTGGCC GGGGCCTACC CAGCGGGGCC CCACACGCAC 
CCCGGGCTGC TCAGGGGGGG AGCGGGTGGG CTGGGGATCA TGGGGCTGCC TCCTCTGCCA 
GCCCCCGGCG AGCCTTGCCC GTTGGCTCAG GAGGAGGTGA TTGAGATCAA CCGGGCAGAT 
CCTCGCCCCA ATGGGGATCC GGCAGCAGCT GCGCTTGCCC ACGAGGACTG CCCAGCCATT 
GACCAGCCTG CCATGTCCCC GGAAGACAAG AGCCCCATCA CGCCTGGAAG CCGTGGCCGC 
TATAGCCGGG ACCGAGCCTG CTTCCTCCTC ACCGACTATG CCCCTTCCCC TGATGGCTCC 
ATCCGAAAAG CCACTGGTGC TCCCCCACTG CCCCCCCAAG ACTGGCGTAA GCCAGGCCCC 
CCAAGCTTCT TGCCCGACCT CAACGCCAAC GCCGCGGCCT GGATATCCCC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006723266.1
CDS	1..2274
Translation	MLSSVCVSSFRGRQGASKQQPAPPPQPPESPPPPPLPPQQQQPAQPGPAASPAGPPAPRGPGDRRAEPCPGLPAAAMGRHGGGGGDSGKIVINVGGVRHETYRSTLRTLPGTRLAGLTEPEAAARFDYDPGADEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELGFWGIDETDVEACCWMTYRQHRDAEEALDSFEAPDPAGAANAANAAGAHDGGLDDEAGAGGGGLDGAGGELKRLCFQDAGGGAGGPPGGAGGAGGTWWRRWQPRVWALFEDPYSSRAARYVAFASLFFILISITTFCLETHEGFIHISNKTVTQASPIPGAPPENITNVEVETEPFLTYVEGVCVVWFTFEFLMRITFCPDKVEFLKSSLNIIDCVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDILGSNHTYFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIPRPPQPGSPNYCKPDPPPPPPPHPHHGSGGISPPPPITPPSMGVTVAGAYPAGPHTHPGLLRGGAGGLGIMGLPPLPAPGEPCPLAQEEVIEINRADPRPNGDPAAAALAHEDCPAIDQPAMSPEDKSPITPGSRGRYSRDRACFLLTDYAPSPDGSIRKATGAPPLPPQDWRKPGPPSFLPDLNANAAAWISP

Target ORF information:

RefSeq Version	XM_006723203.2
Organism	Homo sapiens(human)
Definition	Homo sapiens potassium voltage-gated channel subfamily C member 3 (KCNC3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006723203.2

ORF Insert Sequence:

ATGCTGAGCT CAGTCTGCGT CTCGTCCTTC CGCGGGCGCC AGGGGGCCAG CAAGCAGCAG 
CCGGCGCCAC CGCCGCAGCC GCCCGAGTCC CCGCCGCCGC CACCGCTGCC GCCGCAGCAG 
CAGCAGCCTG CGCAGCCCGG CCCCGCCGCG TCCCCGGCGG GCCCCCCGGC ACCCCGCGGG 
CCCGGGGACC GGCGCGCCGA GCCATGCCCC GGGCTGCCGG CGGCGGCCAT GGGGCGGCAC 
GGCGGCGGCG GTGGCGACAG CGGCAAGATC GTGATCAACG TGGGCGGCGT GCGCCATGAG 
ACGTACCGCT CGACGCTGCG CACCCTGCCG GGGACGCGGC TGGCCGGCCT GACGGAGCCC 
GAGGCGGCGG CACGCTTCGA CTACGACCCG GGCGCCGACG AGTTCTTCTT TGACCGGCAC 
CCGGGAGTCT TCGCGTACGT GCTCAACTAC TACCGCACCG GCAAGCTGCA CTGCCCAGCC 
GACGTGTGCG GGCCCCTGTT TGAGGAGGAG CTCGGCTTCT GGGGCATCGA CGAGACCGAC 
GTGGAGGCCT GCTGCTGGAT GACCTACCGG CAGCATCGCG ACGCTGAGGA GGCGCTCGAC 
TCCTTCGAGG CGCCCGACCC CGCGGGCGCC GCCAACGCCG CCAACGCCGC AGGCGCCCAC 
GACGGAGGCC TGGACGACGA GGCGGGCGCG GGCGGCGGCG GCCTGGACGG AGCGGGCGGC 
GAGCTCAAGC GCCTCTGCTT CCAGGACGCG GGCGGCGGCG CCGGGGGGCC GCCAGGGGGC 
GCGGGCGGCG CGGGCGGCAC ATGGTGGCGC CGCTGGCAGC CCCGCGTGTG GGCGCTCTTC 
GAGGACCCCT ACTCGTCGCG GGCTGCCAGG TATGTGGCCT TCGCCTCCCT CTTCTTCATC 
CTCATCTCCA TCACCACCTT CTGCCTGGAA ACCCATGAGG GCTTCATCCA TATTAGCAAC 
AAGACGGTGA CCCAGGCCTC CCCGATCCCC GGGGCACCTC CGGAGAACAT CACCAACGTG 
GAGGTGGAGA CGGAGCCCTT CCTGACCTAC GTGGAGGGGG TGTGCGTGGT CTGGTTCACC 
TTCGAGTTCC TCATGCGCAT CACCTTCTGC CCAGACAAGG TGGAGTTTCT TAAAAGCAGC 
CTCAACATCA TCGACTGTGT GGCCATCCTG CCCTTCTATC TCGAGGTGGG CCTCTCGGGC 
CTCAGCTCCA AGGCCGCCAA AGACGTGCTG GGCTTCCTGC GGGTGGTCCG CTTCGTCCGC 
ATCCTGCGCA TCTTCAAGCT GACCCGGCAC TTCGTGGGGC TGCGCGTGCT GGGACACACG 
CTCCGCGCCA GCACCAACGA GTTCCTGCTG CTCATCATCT TCCTGGCCCT GGGGGTGCTC 
ATCTTCGCCA CCATGATTTA CTACGCTGAG CGCATTGGCG CCGACCCCGA TGACATCCTG 
GGCTCCAACC ACACCTACTT CAAGAACATC CCCATTGGCT TCTGGTGGGC TGTGGTCACC 
ATGACGACCC TGGGCTATGG AGACATGTAC CCCAAGACGT GGTCGGGGAT GCTGGTCGGG 
GCGCTGTGTG CCCTGGCGGG GGTGCTGACC ATCGCCATGC CTGTGCCCGT CATTGTCAAC 
AACTTTGGCA TGTACTATTC GCTGGCCATG GCCAAGCAGA AGCTGCCCAA GAAGAAGAAC 
AAACACATCC CCCGGCCCCC GCAACCGGGC TCGCCCAACT ACTGCAAGCC TGACCCACCC 
CCGCCACCCC CGCCCCACCC GCACCACGGC AGCGGGGGCA TCAGCCCGCC GCCACCCATC 
ACCCCACCCT CCATGGGGGT GACTGTGGCC GGGGCCTACC CAGCGGGGCC CCACACGCAC 
CCCGGGCTGC TCAGGGGGGG AGCGGGTGGG CTGGGGATCA TGGGGCTGCC TCCTCTGCCA 
GCCCCCGGCG AGCCTTGCCC GTTGGCTCAG GAGGAGGTGA TTGAGATCAA CCGGGCAGAT 
CCTCGCCCCA ATGGGGATCC GGCAGCAGCT GCGCTTGCCC ACGAGGACTG CCCAGCCATT 
GACCAGCCTG CCATGTCCCC GGAAGACAAG AGCCCCATCA CGCCTGGAAG CCGTGGCCGC 
TATAGCCGGG ACCGAGCCTG CTTCCTCCTC ACCGACTATG CCCCTTCCCC TGATGGCTCC 
ATCCGAAAAG CCACTGGTGC TCCCCCACTG CCCCCCCAAG ACTGGCGTAA GCCAGGCCCC 
CCAAGCTTCT TGCCCGACCT CAACGCCAAC GCCGCGGCCT GGATATCCCC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KCNC3 ( XM_011526925.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011525227.1 Homo sapiens potassium voltage-gated channel subfamily C member 3 (KCNC3), transcript variant X4, mRNA.

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CloneID	OHu58555
Clone ID Related Accession (Same CDS sequence)	XM_011526925.2
Accession Version	XM_011526925.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2307bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	potassium voltage-gated channel subfamily C member 3 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011526925.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGAGCT CAGTCTGCGT CTCGTCCTTC CGCGGGCGCC AGGGGGCCAG CAAGCAGCAG 
CCGGCGCCAC CGCCGCAGCC GCCCGAGTCC CCGCCGCCGC CACCGCTGCC GCCGCAGCAG 
CAGCAGCCTG CGCAGCCCGG CCCCGCCGCG TCCCCGGCGG GCCCCCCGGC ACCCCGCGGG 
CCCGGGGACC GGCGCGCCGA GCCATGCCCC GGGCTGCCGG CGGCGGCCAT GGGGCGGCAC 
GGCGGCGGCG GTGGCGACAG CGGCAAGATC GTGATCAACG TGGGCGGCGT GCGCCATGAG 
ACGTACCGCT CGACGCTGCG CACCCTGCCG GGGACGCGGC TGGCCGGCCT GACGGAGCCC 
GAGGCGGCGG CACGCTTCGA CTACGACCCG GGCGCCGACG AGTTCTTCTT TGACCGGCAC 
CCGGGAGTCT TCGCGTACGT GCTCAACTAC TACCGCACCG GCAAGCTGCA CTGCCCAGCC 
GACGTGTGCG GGCCCCTGTT TGAGGAGGAG CTCGGCTTCT GGGGCATCGA CGAGACCGAC 
GTGGAGGCCT GCTGCTGGAT GACCTACCGG CAGCATCGCG ACGCTGAGGA GGCGCTCGAC 
TCCTTCGAGG CGCCCGACCC CGCGGGCGCC GCCAACGCCG CCAACGCCGC AGGCGCCCAC 
GACGGAGGCC TGGACGACGA GGCGGGCGCG GGCGGCGGCG GCCTGGACGG AGCGGGCGGC 
GAGCTCAAGC GCCTCTGCTT CCAGGACGCG GGCGGCGGCG CCGGGGGGCC GCCAGGGGGC 
GCGGGCGGCG CGGGCGGCAC ATGGTGGCGC CGCTGGCAGC CCCGCGTGTG GGCGCTCTTC 
GAGGACCCCT ACTCGTCGCG GGCTGCCAGG TATGTGGCCT TCGCCTCCCT CTTCTTCATC 
CTCATCTCCA TCACCACCTT CTGCCTGGAA ACCCATGAGG GCTTCATCCA TATTAGCAAC 
AAGACGGTGA CCCAGGCCTC CCCGATCCCC GGGGCACCTC CGGAGAACAT CACCAACGTG 
GAGGTGGAGA CGGAGCCCTT CCTGACCTAC GTGGAGGGGG TGTGCGTGGT CTGGTTCACC 
TTCGAGTTCC TCATGCGCAT CACCTTCTGC CCAGACAAGG TGGAGTTTCT TAAAAGCAGC 
CTCAACATCA TCGACTGTGT GGCCATCCTG CCCTTCTATC TCGAGGTGGG CCTCTCGGGC 
CTCAGCTCCA AGGCCGCCAA AGACGTGCTG GGCTTCCTGC GGGTGGTCCG CTTCGTCCGC 
ATCCTGCGCA TCTTCAAGCT GACCCGGCAC TTCGTGGGGC TGCGCGTGCT GGGACACACG 
CTCCGCGCCA GCACCAACGA GTTCCTGCTG CTCATCATCT TCCTGGCCCT GGGGGTGCTC 
ATCTTCGCCA CCATGATTTA CTACGCTGAG CGCATTGGCG CCGACCCCGA TGACATCCTG 
GGCTCCAACC ACACCTACTT CAAGAACATC CCCATTGGCT TCTGGTGGGC TGTGGTCACC 
ATGACGACCC TGGGCTATGG AGACATGTAC CCCAAGACGT GGTCGGGGAT GCTGGTCGGG 
GCGCTGTGTG CCCTGGCGGG GGTGCTGACC ATCGCCATGC CTGTGCCCGT CATTGTCAAC 
AACTTTGGCA TGTACTATTC GCTGGCCATG GCCAAGCAGA AGCTGCCCAA GAAGAAGAAC 
AAACACATCC CCCGGCCCCC GCAACCGGGC TCGCCCAACT ACTGCAAGCC TGACCCACCC 
CCGCCACCCC CGCCCCACCC GCACCACGGC AGCGGGGGCA TCAGCCCGCC GCCACCCATC 
ACCCCACCCT CCATGGGGGT GACTGTGGCC GGGGCCTACC CAGCGGGGCC CCACACGCAC 
CCCGGGCTGC TCAGGGGGGG AGCGGGTGGG CTGGGGATCA TGGGGCTGCC TCCTCTGCCA 
GCCCCCGGCG AGCCTTGCCC GTTGGCTCAG GAGGAGGTGA TTGAGATCAA CCGGGCAGAT 
CCTCGCCCCA ATGGGGATCC GGCAGCAGCT GCGCTTGCCC ACGAGGACTG CCCAGCCATT 
GACCAGCCTG CCATGTCCCC GGAAGACAAG AGCCCCATCA CGCCTGGAAG CCGTGGCCGC 
TATAGCCGGG ACCGAGCCTG CTTCCTCCTC ACCGACTATG CCCCTTCCCC TGATGGCTCC 
ATCCGAAAAG GTTACGAGAA ATCCCGCAGC CTCAGCAGCA TCGCGGGCCT GAGCGGGGTG 
TCCCTGCGCC TCGCGCCCCT TGCCACCCCC CCTGGCTCTC CCCGGGCCGC CCGCCGCGCT 
CCCCCGACCC TGCCCTCCAT CCTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011525227.1
CDS	1..2307
Translation	MLSSVCVSSFRGRQGASKQQPAPPPQPPESPPPPPLPPQQQQPAQPGPAASPAGPPAPRGPGDRRAEPCPGLPAAAMGRHGGGGGDSGKIVINVGGVRHETYRSTLRTLPGTRLAGLTEPEAAARFDYDPGADEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELGFWGIDETDVEACCWMTYRQHRDAEEALDSFEAPDPAGAANAANAAGAHDGGLDDEAGAGGGGLDGAGGELKRLCFQDAGGGAGGPPGGAGGAGGTWWRRWQPRVWALFEDPYSSRAARYVAFASLFFILISITTFCLETHEGFIHISNKTVTQASPIPGAPPENITNVEVETEPFLTYVEGVCVVWFTFEFLMRITFCPDKVEFLKSSLNIIDCVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDILGSNHTYFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIPRPPQPGSPNYCKPDPPPPPPPHPHHGSGGISPPPPITPPSMGVTVAGAYPAGPHTHPGLLRGGAGGLGIMGLPPLPAPGEPCPLAQEEVIEINRADPRPNGDPAAAALAHEDCPAIDQPAMSPEDKSPITPGSRGRYSRDRACFLLTDYAPSPDGSIRKGYEKSRSLSSIAGLSGVSLRLAPLATPPGSPRAARRAPPTLPSIL

Target ORF information:

RefSeq Version	XM_011526925.2
Organism	Homo sapiens(human)
Definition	Homo sapiens potassium voltage-gated channel subfamily C member 3 (KCNC3), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011526925.2

ORF Insert Sequence:

ATGCTGAGCT CAGTCTGCGT CTCGTCCTTC CGCGGGCGCC AGGGGGCCAG CAAGCAGCAG 
CCGGCGCCAC CGCCGCAGCC GCCCGAGTCC CCGCCGCCGC CACCGCTGCC GCCGCAGCAG 
CAGCAGCCTG CGCAGCCCGG CCCCGCCGCG TCCCCGGCGG GCCCCCCGGC ACCCCGCGGG 
CCCGGGGACC GGCGCGCCGA GCCATGCCCC GGGCTGCCGG CGGCGGCCAT GGGGCGGCAC 
GGCGGCGGCG GTGGCGACAG CGGCAAGATC GTGATCAACG TGGGCGGCGT GCGCCATGAG 
ACGTACCGCT CGACGCTGCG CACCCTGCCG GGGACGCGGC TGGCCGGCCT GACGGAGCCC 
GAGGCGGCGG CACGCTTCGA CTACGACCCG GGCGCCGACG AGTTCTTCTT TGACCGGCAC 
CCGGGAGTCT TCGCGTACGT GCTCAACTAC TACCGCACCG GCAAGCTGCA CTGCCCAGCC 
GACGTGTGCG GGCCCCTGTT TGAGGAGGAG CTCGGCTTCT GGGGCATCGA CGAGACCGAC 
GTGGAGGCCT GCTGCTGGAT GACCTACCGG CAGCATCGCG ACGCTGAGGA GGCGCTCGAC 
TCCTTCGAGG CGCCCGACCC CGCGGGCGCC GCCAACGCCG CCAACGCCGC AGGCGCCCAC 
GACGGAGGCC TGGACGACGA GGCGGGCGCG GGCGGCGGCG GCCTGGACGG AGCGGGCGGC 
GAGCTCAAGC GCCTCTGCTT CCAGGACGCG GGCGGCGGCG CCGGGGGGCC GCCAGGGGGC 
GCGGGCGGCG CGGGCGGCAC ATGGTGGCGC CGCTGGCAGC CCCGCGTGTG GGCGCTCTTC 
GAGGACCCCT ACTCGTCGCG GGCTGCCAGG TATGTGGCCT TCGCCTCCCT CTTCTTCATC 
CTCATCTCCA TCACCACCTT CTGCCTGGAA ACCCATGAGG GCTTCATCCA TATTAGCAAC 
AAGACGGTGA CCCAGGCCTC CCCGATCCCC GGGGCACCTC CGGAGAACAT CACCAACGTG 
GAGGTGGAGA CGGAGCCCTT CCTGACCTAC GTGGAGGGGG TGTGCGTGGT CTGGTTCACC 
TTCGAGTTCC TCATGCGCAT CACCTTCTGC CCAGACAAGG TGGAGTTTCT TAAAAGCAGC 
CTCAACATCA TCGACTGTGT GGCCATCCTG CCCTTCTATC TCGAGGTGGG CCTCTCGGGC 
CTCAGCTCCA AGGCCGCCAA AGACGTGCTG GGCTTCCTGC GGGTGGTCCG CTTCGTCCGC 
ATCCTGCGCA TCTTCAAGCT GACCCGGCAC TTCGTGGGGC TGCGCGTGCT GGGACACACG 
CTCCGCGCCA GCACCAACGA GTTCCTGCTG CTCATCATCT TCCTGGCCCT GGGGGTGCTC 
ATCTTCGCCA CCATGATTTA CTACGCTGAG CGCATTGGCG CCGACCCCGA TGACATCCTG 
GGCTCCAACC ACACCTACTT CAAGAACATC CCCATTGGCT TCTGGTGGGC TGTGGTCACC 
ATGACGACCC TGGGCTATGG AGACATGTAC CCCAAGACGT GGTCGGGGAT GCTGGTCGGG 
GCGCTGTGTG CCCTGGCGGG GGTGCTGACC ATCGCCATGC CTGTGCCCGT CATTGTCAAC 
AACTTTGGCA TGTACTATTC GCTGGCCATG GCCAAGCAGA AGCTGCCCAA GAAGAAGAAC 
AAACACATCC CCCGGCCCCC GCAACCGGGC TCGCCCAACT ACTGCAAGCC TGACCCACCC 
CCGCCACCCC CGCCCCACCC GCACCACGGC AGCGGGGGCA TCAGCCCGCC GCCACCCATC 
ACCCCACCCT CCATGGGGGT GACTGTGGCC GGGGCCTACC CAGCGGGGCC CCACACGCAC 
CCCGGGCTGC TCAGGGGGGG AGCGGGTGGG CTGGGGATCA TGGGGCTGCC TCCTCTGCCA 
GCCCCCGGCG AGCCTTGCCC GTTGGCTCAG GAGGAGGTGA TTGAGATCAA CCGGGCAGAT 
CCTCGCCCCA ATGGGGATCC GGCAGCAGCT GCGCTTGCCC ACGAGGACTG CCCAGCCATT 
GACCAGCCTG CCATGTCCCC GGAAGACAAG AGCCCCATCA CGCCTGGAAG CCGTGGCCGC 
TATAGCCGGG ACCGAGCCTG CTTCCTCCTC ACCGACTATG CCCCTTCCCC TGATGGCTCC 
ATCCGAAAAG GTTACGAGAA ATCCCGCAGC CTCAGCAGCA TCGCGGGCCT GAGCGGGGTG 
TCCCTGCGCC TCGCGCCCCT TGCCACCCCC CCTGGCTCTC CCCGGGCCGC CCGCCGCGCT 
CCCCCGACCC TGCCCTCCAT CCTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KCNC3 ( XM_011526928.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011525230.1 Homo sapiens potassium voltage-gated channel subfamily C member 3 (KCNC3), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu58556
Clone ID Related Accession (Same CDS sequence)	XM_011526928.2
Accession Version	XM_011526928.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2187bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	potassium voltage-gated channel subfamily C member 3 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011526928.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGAGCT CAGTCTGCGT CTCGTCCTTC CGCGGGCGCC AGGGGGCCAG CAAGCAGCAG 
CCGGCGCCAC CGCCGCAGCC GCCCGAGTCC CCGCCGCCGC CACCGCTGCC GCCGCAGCAG 
CAGCAGCCTG CGCAGCCCGG CCCCGCCGCG TCCCCGGCGG GCCCCCCGGC ACCCCGCGGG 
CCCGGGGACC GGCGCGCCGA GCCATGCCCC GGGCTGCCGG CGGCGGCCAT GGGGCGGCAC 
GGCGGCGGCG GTGGCGACAG CGGCAAGATC GTGATCAACG TGGGCGGCGT GCGCCATGAG 
ACGTACCGCT CGACGCTGCG CACCCTGCCG GGGACGCGGC TGGCCGGCCT GACGGAGCCC 
GAGGCGGCGG CACGCTTCGA CTACGACCCG GGCGCCGACG AGTTCTTCTT TGACCGGCAC 
CCGGGAGTCT TCGCGTACGT GCTCAACTAC TACCGCACCG GCAAGCTGCA CTGCCCAGCC 
GACGTGTGCG GGCCCCTGTT TGAGGAGGAG CTCGGCTTCT GGGGCATCGA CGAGACCGAC 
GTGGAGGCCT GCTGCTGGAT GACCTACCGG CAGCATCGCG ACGCTGAGGA GGCGCTCGAC 
TCCTTCGAGG CGCCCGACCC CGCGGGCGCC GCCAACGCCG CCAACGCCGC AGGCGCCCAC 
GACGGAGGCC TGGACGACGA GGCGGGCGCG GGCGGCGGCG GCCTGGACGG AGCGGGCGGC 
GAGCTCAAGC GCCTCTGCTT CCAGGACGCG GGCGGCGGCG CCGGGGGGCC GCCAGGGGGC 
GCGGGCGGCG CGGGCGGCAC ATGGTGGCGC CGCTGGCAGC CCCGCGTGTG GGCGCTCTTC 
GAGGACCCCT ACTCGTCGCG GGCTGCCAGG TATGTGGCCT TCGCCTCCCT CTTCTTCATC 
CTCATCTCCA TCACCACCTT CTGCCTGGAA ACCCATGAGG GCTTCATCCA TATTAGCAAC 
AAGACGGTGA CCCAGGCCTC CCCGATCCCC GGGGCACCTC CGGAGAACAT CACCAACGTG 
GAGGTGGAGA CGGAGCCCTT CCTGACCTAC GTGGAGGGGG TGTGCGTGGT CTGGTTCACC 
TTCGAGTTCC TCATGCGCAT CACCTTCTGC CCAGACAAGG TGGAGTTTCT TAAAAGCAGC 
CTCAACATCA TCGACTGTGT GGCCATCCTG CCCTTCTATC TCGAGGTGGG CCTCTCGGGC 
CTCAGCTCCA AGGCCGCCAA AGACGTGCTG GGCTTCCTGC GGGTGGTCCG CTTCGTCCGC 
ATCCTGCGCA TCTTCAAGCT GACCCGGCAC TTCGTGGGGC TGCGCGTGCT GGGACACACG 
CTCCGCGCCA GCACCAACGA GTTCCTGCTG CTCATCATCT TCCTGGCCCT GGGGGTGCTC 
ATCTTCGCCA CCATGATTTA CTACGCTGAG CGCATTGGCG CCGACCCCGA TGACATCCTG 
GGCTCCAACC ACACCTACTT CAAGAACATC CCCATTGGCT TCTGGTGGGC TGTGGTCACC 
ATGACGACCC TGGGCTATGG AGACATGTAC CCCAAGACGT GGTCGGGGAT GCTGGTCGGG 
GCGCTGTGTG CCCTGGCGGG GGTGCTGACC ATCGCCATGC CTGTGCCCGT CATTGTCAAC 
AACTTTGGCA TGTACTATTC GCTGGCCATG GCCAAGCAGA AGCTGCCCAA GAAGAAGAAC 
AAACACATCC CCCGGCCCCC GCAACCGGGC TCGCCCAACT ACTGCAAGCC TGACCCACCC 
CCGCCACCCC CGCCCCACCC GCACCACGGC AGCGGGGGCA TCAGCCCGCC GCCACCCATC 
ACCCCACCCT CCATGGGGGT GACTGTGGCC GGGGCCTACC CAGCGGGGCC CCACACGCAC 
CCCGGGCTGC TCAGGGGGGG AGCGGGTGGG CTGGGGATCA TGGGGCTGCC TCCTCTGCCA 
GCCCCCGGCG AGCCTTGCCC GTTGGCTCAG GAGGAGGTGA TTGAGATCAA CCGGGCAGAT 
CCTCGCCCCA ATGGGGATCC GGCAGCAGCT GCGCTTGCCC ACGAGGACTG CCCAGCCATT 
GACCAGCCTG CCATGTCCCC GGAAGACAAG AGCCCCATCA CGCCTGGAAG CCGTGGCCGC 
TATAGCCGGG ACCGAGCCTG CTTCCTCCTC ACCGACTATG CCCCTTCCCC TGATGGCTCC 
ATCCGAAAAG CTCTTGTCAC CGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011525230.1
CDS	1..2187
Translation	MLSSVCVSSFRGRQGASKQQPAPPPQPPESPPPPPLPPQQQQPAQPGPAASPAGPPAPRGPGDRRAEPCPGLPAAAMGRHGGGGGDSGKIVINVGGVRHETYRSTLRTLPGTRLAGLTEPEAAARFDYDPGADEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELGFWGIDETDVEACCWMTYRQHRDAEEALDSFEAPDPAGAANAANAAGAHDGGLDDEAGAGGGGLDGAGGELKRLCFQDAGGGAGGPPGGAGGAGGTWWRRWQPRVWALFEDPYSSRAARYVAFASLFFILISITTFCLETHEGFIHISNKTVTQASPIPGAPPENITNVEVETEPFLTYVEGVCVVWFTFEFLMRITFCPDKVEFLKSSLNIIDCVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDILGSNHTYFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIPRPPQPGSPNYCKPDPPPPPPPHPHHGSGGISPPPPITPPSMGVTVAGAYPAGPHTHPGLLRGGAGGLGIMGLPPLPAPGEPCPLAQEEVIEINRADPRPNGDPAAAALAHEDCPAIDQPAMSPEDKSPITPGSRGRYSRDRACFLLTDYAPSPDGSIRKALVTA

Target ORF information:

RefSeq Version	XM_011526928.2
Organism	Homo sapiens(human)
Definition	Homo sapiens potassium voltage-gated channel subfamily C member 3 (KCNC3), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011526928.2

ORF Insert Sequence:

ATGCTGAGCT CAGTCTGCGT CTCGTCCTTC CGCGGGCGCC AGGGGGCCAG CAAGCAGCAG 
CCGGCGCCAC CGCCGCAGCC GCCCGAGTCC CCGCCGCCGC CACCGCTGCC GCCGCAGCAG 
CAGCAGCCTG CGCAGCCCGG CCCCGCCGCG TCCCCGGCGG GCCCCCCGGC ACCCCGCGGG 
CCCGGGGACC GGCGCGCCGA GCCATGCCCC GGGCTGCCGG CGGCGGCCAT GGGGCGGCAC 
GGCGGCGGCG GTGGCGACAG CGGCAAGATC GTGATCAACG TGGGCGGCGT GCGCCATGAG 
ACGTACCGCT CGACGCTGCG CACCCTGCCG GGGACGCGGC TGGCCGGCCT GACGGAGCCC 
GAGGCGGCGG CACGCTTCGA CTACGACCCG GGCGCCGACG AGTTCTTCTT TGACCGGCAC 
CCGGGAGTCT TCGCGTACGT GCTCAACTAC TACCGCACCG GCAAGCTGCA CTGCCCAGCC 
GACGTGTGCG GGCCCCTGTT TGAGGAGGAG CTCGGCTTCT GGGGCATCGA CGAGACCGAC 
GTGGAGGCCT GCTGCTGGAT GACCTACCGG CAGCATCGCG ACGCTGAGGA GGCGCTCGAC 
TCCTTCGAGG CGCCCGACCC CGCGGGCGCC GCCAACGCCG CCAACGCCGC AGGCGCCCAC 
GACGGAGGCC TGGACGACGA GGCGGGCGCG GGCGGCGGCG GCCTGGACGG AGCGGGCGGC 
GAGCTCAAGC GCCTCTGCTT CCAGGACGCG GGCGGCGGCG CCGGGGGGCC GCCAGGGGGC 
GCGGGCGGCG CGGGCGGCAC ATGGTGGCGC CGCTGGCAGC CCCGCGTGTG GGCGCTCTTC 
GAGGACCCCT ACTCGTCGCG GGCTGCCAGG TATGTGGCCT TCGCCTCCCT CTTCTTCATC 
CTCATCTCCA TCACCACCTT CTGCCTGGAA ACCCATGAGG GCTTCATCCA TATTAGCAAC 
AAGACGGTGA CCCAGGCCTC CCCGATCCCC GGGGCACCTC CGGAGAACAT CACCAACGTG 
GAGGTGGAGA CGGAGCCCTT CCTGACCTAC GTGGAGGGGG TGTGCGTGGT CTGGTTCACC 
TTCGAGTTCC TCATGCGCAT CACCTTCTGC CCAGACAAGG TGGAGTTTCT TAAAAGCAGC 
CTCAACATCA TCGACTGTGT GGCCATCCTG CCCTTCTATC TCGAGGTGGG CCTCTCGGGC 
CTCAGCTCCA AGGCCGCCAA AGACGTGCTG GGCTTCCTGC GGGTGGTCCG CTTCGTCCGC 
ATCCTGCGCA TCTTCAAGCT GACCCGGCAC TTCGTGGGGC TGCGCGTGCT GGGACACACG 
CTCCGCGCCA GCACCAACGA GTTCCTGCTG CTCATCATCT TCCTGGCCCT GGGGGTGCTC 
ATCTTCGCCA CCATGATTTA CTACGCTGAG CGCATTGGCG CCGACCCCGA TGACATCCTG 
GGCTCCAACC ACACCTACTT CAAGAACATC CCCATTGGCT TCTGGTGGGC TGTGGTCACC 
ATGACGACCC TGGGCTATGG AGACATGTAC CCCAAGACGT GGTCGGGGAT GCTGGTCGGG 
GCGCTGTGTG CCCTGGCGGG GGTGCTGACC ATCGCCATGC CTGTGCCCGT CATTGTCAAC 
AACTTTGGCA TGTACTATTC GCTGGCCATG GCCAAGCAGA AGCTGCCCAA GAAGAAGAAC 
AAACACATCC CCCGGCCCCC GCAACCGGGC TCGCCCAACT ACTGCAAGCC TGACCCACCC 
CCGCCACCCC CGCCCCACCC GCACCACGGC AGCGGGGGCA TCAGCCCGCC GCCACCCATC 
ACCCCACCCT CCATGGGGGT GACTGTGGCC GGGGCCTACC CAGCGGGGCC CCACACGCAC 
CCCGGGCTGC TCAGGGGGGG AGCGGGTGGG CTGGGGATCA TGGGGCTGCC TCCTCTGCCA 
GCCCCCGGCG AGCCTTGCCC GTTGGCTCAG GAGGAGGTGA TTGAGATCAA CCGGGCAGAT 
CCTCGCCCCA ATGGGGATCC GGCAGCAGCT GCGCTTGCCC ACGAGGACTG CCCAGCCATT 
GACCAGCCTG CCATGTCCCC GGAAGACAAG AGCCCCATCA CGCCTGGAAG CCGTGGCCGC 
TATAGCCGGG ACCGAGCCTG CTTCCTCCTC ACCGACTATG CCCCTTCCCC TGATGGCTCC 
ATCCGAAAAG CTCTTGTCAC CGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A KCNC3 mutation causes a neurodevelopmental, non-progressive SCA13 subtype associated with dominant negative effects and aberrant EGFR trafficking.
PloS one12(5)e0173565(2017)
Khare S,Nick JA,Zhang Y,Galeano K,Butler B,Khoshbouei H,Rayaprolu S,Hathorn T,Ranum LPW,Smithson L,Golde TE,Paucar M,Morse R,Raff M,Simon J,Nordenskj?ld M,Wirdefeldt K,Rincon-Limas DE,Lewis J,Kaczmarek LK,Fernandez-Funez P,Nick HS,Waters MF

Kv3.3 potassium channels and spinocerebellar ataxia.
The Journal of physiology594(16)4677-84(2016 08)
Zhang Y,Kaczmarek LK

Kv3.3 Channels Bind Hax-1 and Arp2/3 to Assemble a Stable Local Actin Network that Regulates Channel Gating.
Cell165(2)434-448(2016 Apr)
Zhang Y,Zhang XF,Fleming MR,Amiri A,El-Hassar L,Surguchev AA,Hyland C,Jenkins DP,Desai R,Brown MR,Gazula VR,Waters MF,Large CH,Horvath TL,Navaratnam D,Vaccarino FM,Forscher P,Kaczmarek LK

Voltage-Gated K+ Channel, Kv3.3 Is Involved in Hemin-Induced K562 Differentiation.
PloS one11(2)e0148633(2016)
Song MS,Choi SY,Ryu PD,Lee SY

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KCNC3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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