Gene Symbol | CDRT1 |
Entrez Gene ID | 374286 |
Full Name | CMT1A duplicated region transcript 1 |
Synonyms | C170RF1,C17ORF1,C17ORF1A,FBXW10B,FBXW10P1,HREP,SM25H2 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]. |
Disorder MIM: |