Gene Symbol | ING1 |
Entrez Gene ID | 3621 |
Full Name | inhibitor of growth family member 1 |
Synonyms | p24ING1c,p33,p33ING1,p33ING1b,p47,p47ING1a |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]. |
Disorder MIM: | |
Disorder Html: | Squamous cell carcinoma, head and neck, somatic, 275355 (3) |