AQP4 cDNA ORF clone, Homo sapiens(human)

The following AQP4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the AQP4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu23904 NM_001364286.1
Latest version!
Homo sapiens aquaporin 4 (AQP4), transcript variant 1, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$99.50-$139.30
$199.00
OHu23904 NM_004028.4
Latest version!
Homo sapiens aquaporin 4 (AQP4), transcript variant 2, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$99.50-$139.30
$199.00
OHu24057 NM_001650.7
Latest version!
Homo sapiens aquaporin 4 (AQP4), transcript variant 1, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$99.50-$139.30
$199.00
OHu102796 NM_001317384.2
Latest version!
Homo sapiens aquaporin 4 (AQP4), transcript variant 1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $223.30
$319.00
OHu56344 XM_011525942.3
Latest version!
Homo sapiens aquaporin 4 (AQP4), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $139.30
$199.00
OHu102800 NM_001317387.2
Latest version!
Homo sapiens aquaporin 4 (AQP4), transcript variant 3, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $139.30
$199.00
OHu106841 NM_001364287.1
Latest version!
Homo sapiens aquaporin 4 (AQP4), transcript variant 1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $139.30
$199.00
OHu106841 NM_001364289.1
Latest version!
Homo sapiens aquaporin 4 (AQP4), transcript variant 2, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $139.30
$199.00
View Old Accession Versions >>
OHu24057 NM_001650.5 Homo sapiens aquaporin 4 (AQP4), transcript variant 1, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$99.50-$139.30
$199.00
OHu24057 NM_001650.4 Homo sapiens aquaporin 4 (AQP4), transcript variant a, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$99.50-$139.30
$199.00
OHu102796 NM_001317384.1 Homo sapiens aquaporin 4 (AQP4), transcript variant 1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $223.30
$319.00
OHu24057 NM_001650.6 Homo sapiens aquaporin 4 (AQP4), transcript variant 1, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$99.50-$139.30
$199.00
OHu23904 NM_004028.3 Homo sapiens aquaporin 4 (AQP4), transcript variant b, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$99.50-$139.30
$199.00
OHu102800 NM_001317387.1 Homo sapiens aquaporin 4 (AQP4), transcript variant 3, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $139.30
$199.00
OHu56344 XM_011525942.2 Homo sapiens aquaporin 4 (AQP4), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $139.30
$199.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

  • Reference Sequences (Refseq)
    CloneID OHu23904
    Clone ID Related Accession (Same CDS sequence) NM_001364286.1 , NM_004028.4 , NM_004028.3
    Accession Version NM_001364286.1 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 906bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-08-20
    Organism Homo sapiens(human)
    Product aquaporin-4 isoform M23
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HQ901095.1, AK222684.1, DT220791.1, DA244620.1, AC018371.10 and BU687682.1. Transcript Variant: This variant (1, also known as hMIWC2) represents the predominant transcript and encodes four isoforms, resulting from the use of two alternative in-frame translation initiation codons and two alternative in-frame translation termination codons. This RefSeq represents isoform M23, which results from the use of the downstream in-frame AUG start codon and the upstream UGA stop codon. Isoform M23 has a shorter N-terminus compared to isoform M1. An alternatively spliced transcript variant (NM_004028.4) encodes the same isoform. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.43905.1, SRR1803616.132676.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: experimental evidence (PMID:20007705) ##RefSeq-Attributes-END## COMPLETENESS: full length.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGGTGGCTT TCAAAGGGGT CTGGACTCAA GCTTTCTGGA AAGCAGTCAC AGCGGAATTT 
    CTGGCCATGC TTATTTTTGT TCTCCTCAGC CTGGGATCCA CCATCAACTG GGGTGGAACA
    GAAAAGCCTT TACCGGTCGA CATGGTTCTC ATCTCCCTTT GCTTTGGACT CAGCATTGCA
    ACCATGGTGC AGTGCTTTGG CCATATCAGC GGTGGCCACA TCAACCCTGC AGTGACTGTG
    GCCATGGTGT GCACCAGGAA GATCAGCATC GCCAAGTCTG TCTTCTACAT CGCAGCCCAG
    TGCCTGGGGG CCATCATTGG AGCAGGAATC CTCTATCTGG TCACACCTCC CAGTGTGGTG
    GGAGGCCTGG GAGTCACCAT GGTTCATGGA AATCTTACCG CTGGTCATGG TCTCCTGGTT
    GAGTTGATAA TCACATTTCA ATTGGTGTTT ACTATCTTTG CCAGCTGTGA TTCCAAACGG
    ACTGATGTCA CTGGCTCAAT AGCTTTAGCA ATTGGATTTT CTGTTGCAAT TGGACATTTA
    TTTGCAATCA ATTATACTGG TGCCAGCATG AATCCCGCCC GATCCTTTGG ACCTGCAGTT
    ATCATGGGAA ATTGGGAAAA CCATTGGATA TATTGGGTTG GGCCCATCAT AGGAGCTGTC
    CTCGCTGGTG GCCTTTATGA GTATGTCTTC TGTCCAGATG TTGAATTCAA ACGTCGTTTT
    AAAGAAGCCT TCAGCAAAGC TGCCCAGCAA ACAAAAGGAA GCTACATGGA GGTGGAGGAC
    AACAGGAGTC AGGTAGAGAC GGATGACCTG ATTCTAAAAC CTGGAGTGGT GCATGTGATT
    GACGTTGACC GGGGAGAGGA GAAGAAGGGG AAAGACCAAT CTGGAGAGGT ATTGTCTTCA
    GTATGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001351215.1
    CDS181..1086
    Translation

    Target ORF information:

    RefSeq Version NM_001364286.1
    Organism Homo sapiens(human)
    Definition Homo sapiens aquaporin 4 (AQP4), transcript variant 1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001364286.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGGTGGCTT TCAAAGGGGT CTGGACTCAA GCTTTCTGGA AAGCAGTCAC AGCGGAATTT 
    CTGGCCATGC TTATTTTTGT TCTCCTCAGC CTGGGATCCA CCATCAACTG GGGTGGAACA
    GAAAAGCCTT TACCGGTCGA CATGGTTCTC ATCTCCCTTT GCTTTGGACT CAGCATTGCA
    ACCATGGTGC AGTGCTTTGG CCATATCAGC GGTGGCCACA TCAACCCTGC AGTGACTGTG
    GCCATGGTGT GCACCAGGAA GATCAGCATC GCCAAGTCTG TCTTCTACAT CGCAGCCCAG
    TGCCTGGGGG CCATCATTGG AGCAGGAATC CTCTATCTGG TCACACCTCC CAGTGTGGTG
    GGAGGCCTGG GAGTCACCAT GGTTCATGGA AATCTTACCG CTGGTCATGG TCTCCTGGTT
    GAGTTGATAA TCACATTTCA ATTGGTGTTT ACTATCTTTG CCAGCTGTGA TTCCAAACGG
    ACTGATGTCA CTGGCTCAAT AGCTTTAGCA ATTGGATTTT CTGTTGCAAT TGGACATTTA
    TTTGCAATCA ATTATACTGG TGCCAGCATG AATCCCGCCC GATCCTTTGG ACCTGCAGTT
    ATCATGGGAA ATTGGGAAAA CCATTGGATA TATTGGGTTG GGCCCATCAT AGGAGCTGTC
    CTCGCTGGTG GCCTTTATGA GTATGTCTTC TGTCCAGATG TTGAATTCAA ACGTCGTTTT
    AAAGAAGCCT TCAGCAAAGC TGCCCAGCAA ACAAAAGGAA GCTACATGGA GGTGGAGGAC
    AACAGGAGTC AGGTAGAGAC GGATGACCTG ATTCTAAAAC CTGGAGTGGT GCATGTGATT
    GACGTTGACC GGGGAGAGGA GAAGAAGGGG AAAGACCAAT CTGGAGAGGT ATTGTCTTCA
    GTATGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu23904
    Clone ID Related Accession (Same CDS sequence) NM_001364286.1 , NM_004028.4 , NM_004028.3
    Accession Version NM_004028.4 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 906bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-08-20
    Organism Homo sapiens(human)
    Product aquaporin-4 isoform M23
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC018371.10, U34845.1, HQ901095.1, BC030745.1 and BU687682.1. On Dec 2, 2015 this sequence version replaced NM_004028.3. Transcript Variant: This variant (2, also known as hMIWC1) is alternatively spliced at the 5' end, which causes translation initiation from an in-frame, downstream start codon, compared to variant 1. Variant 2 encodes two isoforms, resulting from the use of alternative in-frame translation termination codons. The encoded isoform (M23), which results from the use of the upstream UGA stop codon, has a shorter N-terminus compared to isoform M1. This isoform is the same as that represented in NM_001364286.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.223531.1, SRR1660805.39318.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144333, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGGTGGCTT TCAAAGGGGT CTGGACTCAA GCTTTCTGGA AAGCAGTCAC AGCGGAATTT 
    CTGGCCATGC TTATTTTTGT TCTCCTCAGC CTGGGATCCA CCATCAACTG GGGTGGAACA
    GAAAAGCCTT TACCGGTCGA CATGGTTCTC ATCTCCCTTT GCTTTGGACT CAGCATTGCA
    ACCATGGTGC AGTGCTTTGG CCATATCAGC GGTGGCCACA TCAACCCTGC AGTGACTGTG
    GCCATGGTGT GCACCAGGAA GATCAGCATC GCCAAGTCTG TCTTCTACAT CGCAGCCCAG
    TGCCTGGGGG CCATCATTGG AGCAGGAATC CTCTATCTGG TCACACCTCC CAGTGTGGTG
    GGAGGCCTGG GAGTCACCAT GGTTCATGGA AATCTTACCG CTGGTCATGG TCTCCTGGTT
    GAGTTGATAA TCACATTTCA ATTGGTGTTT ACTATCTTTG CCAGCTGTGA TTCCAAACGG
    ACTGATGTCA CTGGCTCAAT AGCTTTAGCA ATTGGATTTT CTGTTGCAAT TGGACATTTA
    TTTGCAATCA ATTATACTGG TGCCAGCATG AATCCCGCCC GATCCTTTGG ACCTGCAGTT
    ATCATGGGAA ATTGGGAAAA CCATTGGATA TATTGGGTTG GGCCCATCAT AGGAGCTGTC
    CTCGCTGGTG GCCTTTATGA GTATGTCTTC TGTCCAGATG TTGAATTCAA ACGTCGTTTT
    AAAGAAGCCT TCAGCAAAGC TGCCCAGCAA ACAAAAGGAA GCTACATGGA GGTGGAGGAC
    AACAGGAGTC AGGTAGAGAC GGATGACCTG ATTCTAAAAC CTGGAGTGGT GCATGTGATT
    GACGTTGACC GGGGAGAGGA GAAGAAGGGG AAAGACCAAT CTGGAGAGGT ATTGTCTTCA
    GTATGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_004019.1
    CDS349..1254
    Translation

    Target ORF information:

    RefSeq Version NM_004028.4
    Organism Homo sapiens(human)
    Definition Homo sapiens aquaporin 4 (AQP4), transcript variant 2, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_004028.4

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGGTGGCTT TCAAAGGGGT CTGGACTCAA GCTTTCTGGA AAGCAGTCAC AGCGGAATTT 
    CTGGCCATGC TTATTTTTGT TCTCCTCAGC CTGGGATCCA CCATCAACTG GGGTGGAACA
    GAAAAGCCTT TACCGGTCGA CATGGTTCTC ATCTCCCTTT GCTTTGGACT CAGCATTGCA
    ACCATGGTGC AGTGCTTTGG CCATATCAGC GGTGGCCACA TCAACCCTGC AGTGACTGTG
    GCCATGGTGT GCACCAGGAA GATCAGCATC GCCAAGTCTG TCTTCTACAT CGCAGCCCAG
    TGCCTGGGGG CCATCATTGG AGCAGGAATC CTCTATCTGG TCACACCTCC CAGTGTGGTG
    GGAGGCCTGG GAGTCACCAT GGTTCATGGA AATCTTACCG CTGGTCATGG TCTCCTGGTT
    GAGTTGATAA TCACATTTCA ATTGGTGTTT ACTATCTTTG CCAGCTGTGA TTCCAAACGG
    ACTGATGTCA CTGGCTCAAT AGCTTTAGCA ATTGGATTTT CTGTTGCAAT TGGACATTTA
    TTTGCAATCA ATTATACTGG TGCCAGCATG AATCCCGCCC GATCCTTTGG ACCTGCAGTT
    ATCATGGGAA ATTGGGAAAA CCATTGGATA TATTGGGTTG GGCCCATCAT AGGAGCTGTC
    CTCGCTGGTG GCCTTTATGA GTATGTCTTC TGTCCAGATG TTGAATTCAA ACGTCGTTTT
    AAAGAAGCCT TCAGCAAAGC TGCCCAGCAA ACAAAAGGAA GCTACATGGA GGTGGAGGAC
    AACAGGAGTC AGGTAGAGAC GGATGACCTG ATTCTAAAAC CTGGAGTGGT GCATGTGATT
    GACGTTGACC GGGGAGAGGA GAAGAAGGGG AAAGACCAAT CTGGAGAGGT ATTGTCTTCA
    GTATGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu23904
    Clone ID Related Accession (Same CDS sequence) NM_001364286.1 , NM_004028.4 , NM_004028.3
    Accession Version NM_004028.3 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 906bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2015-03-14
    Organism Homo sapiens(Human)
    Product aquaporin-4 isoform b
    Comment

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGGTGGCTT TCAAAGGGGT CTGGACTCAA GCTTTCTGGA AAGCAGTCAC AGCGGAATTT 
    CTGGCCATGC TTATTTTTGT TCTCCTCAGC CTGGGATCCA CCATCAACTG GGGTGGAACA
    GAAAAGCCTT TACCGGTCGA CATGGTTCTC ATCTCCCTTT GCTTTGGACT CAGCATTGCA
    ACCATGGTGC AGTGCTTTGG CCATATCAGC GGTGGCCACA TCAACCCTGC AGTGACTGTG
    GCCATGGTGT GCACCAGGAA GATCAGCATC GCCAAGTCTG TCTTCTACAT CGCAGCCCAG
    TGCCTGGGGG CCATCATTGG AGCAGGAATC CTCTATCTGG TCACACCTCC CAGTGTGGTG
    GGAGGCCTGG GAGTCACCAT GGTTCATGGA AATCTTACCG CTGGTCATGG TCTCCTGGTT
    GAGTTGATAA TCACATTTCA ATTGGTGTTT ACTATCTTTG CCAGCTGTGA TTCCAAACGG
    ACTGATGTCA CTGGCTCAAT AGCTTTAGCA ATTGGATTTT CTGTTGCAAT TGGACATTTA
    TTTGCAATCA ATTATACTGG TGCCAGCATG AATCCCGCCC GATCCTTTGG ACCTGCAGTT
    ATCATGGGAA ATTGGGAAAA CCATTGGATA TATTGGGTTG GGCCCATCAT AGGAGCTGTC
    CTCGCTGGTG GCCTTTATGA GTATGTCTTC TGTCCAGATG TTGAATTCAA ACGTCGTTTT
    AAAGAAGCCT TCAGCAAAGC TGCCCAGCAA ACAAAAGGAA GCTACATGGA GGTGGAGGAC
    AACAGGAGTC AGGTAGAGAC GGATGACCTG ATTCTAAAAC CTGGAGTGGT GCATGTGATT
    GACGTTGACC GGGGAGAGGA GAAGAAGGGG AAAGACCAAT CTGGAGAGGT ATTGTCTTCA
    GTATGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_004019.1
    Translation

    Target ORF information:

    RefSeq Version NM_004028.3
    Organism Homo sapiens(Human)
    Definition Homo sapiens aquaporin 4 (AQP4), transcript variant b, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_004028.3

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGGTGGCTT TCAAAGGGGT CTGGACTCAA GCTTTCTGGA AAGCAGTCAC AGCGGAATTT 
    CTGGCCATGC TTATTTTTGT TCTCCTCAGC CTGGGATCCA CCATCAACTG GGGTGGAACA
    GAAAAGCCTT TACCGGTCGA CATGGTTCTC ATCTCCCTTT GCTTTGGACT CAGCATTGCA
    ACCATGGTGC AGTGCTTTGG CCATATCAGC GGTGGCCACA TCAACCCTGC AGTGACTGTG
    GCCATGGTGT GCACCAGGAA GATCAGCATC GCCAAGTCTG TCTTCTACAT CGCAGCCCAG
    TGCCTGGGGG CCATCATTGG AGCAGGAATC CTCTATCTGG TCACACCTCC CAGTGTGGTG
    GGAGGCCTGG GAGTCACCAT GGTTCATGGA AATCTTACCG CTGGTCATGG TCTCCTGGTT
    GAGTTGATAA TCACATTTCA ATTGGTGTTT ACTATCTTTG CCAGCTGTGA TTCCAAACGG
    ACTGATGTCA CTGGCTCAAT AGCTTTAGCA ATTGGATTTT CTGTTGCAAT TGGACATTTA
    TTTGCAATCA ATTATACTGG TGCCAGCATG AATCCCGCCC GATCCTTTGG ACCTGCAGTT
    ATCATGGGAA ATTGGGAAAA CCATTGGATA TATTGGGTTG GGCCCATCAT AGGAGCTGTC
    CTCGCTGGTG GCCTTTATGA GTATGTCTTC TGTCCAGATG TTGAATTCAA ACGTCGTTTT
    AAAGAAGCCT TCAGCAAAGC TGCCCAGCAA ACAAAAGGAA GCTACATGGA GGTGGAGGAC
    AACAGGAGTC AGGTAGAGAC GGATGACCTG ATTCTAAAAC CTGGAGTGGT GCATGTGATT
    GACGTTGACC GGGGAGAGGA GAAGAAGGGG AAAGACCAAT CTGGAGAGGT ATTGTCTTCA
    GTATGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu24057
    Clone ID Related Accession (Same CDS sequence) NM_001650.5 , NM_001650.6 , NM_001650.4 , NM_001650.7
    Accession Version NM_001650.5 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 972bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2017-05-06
    Organism Homo sapiens(Human)
    Product aquaporin-4 isoform M1
    Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC018371.10, HQ901095.1, BC030745.1 and BU687682.1. This sequence is a reference standard in the RefSeqGene project. On Dec 2, 2015 this sequence version replaced NM_001650.4. Transcript Variant: This variant (1, also known as hMIWC2) represents the predominant transcript and encodes two isoforms, which result from the use of alternative in-frame translation termination codons. The shorter isoform (M1) results from translation termination at the upstream UGA stop codon (nt 1125-1127), while the longer isoform (M1x) results from UGA stop codon readthrough to the downstream UAA termination codon (nt 1212-1214). This RefSeq represents the shorter isoform. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.43905.1, SRR1803616.132676.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2147920, SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGAGTGACA GACCCACAGC AAGGCGGTGG GGTAAGTGTG GACCTTTGTG TACCAGAGAG 
    AACATCATGG TGGCTTTCAA AGGGGTCTGG ACTCAAGCTT TCTGGAAAGC AGTCACAGCG
    GAATTTCTGG CCATGCTTAT TTTTGTTCTC CTCAGCCTGG GATCCACCAT CAACTGGGGT
    GGAACAGAAA AGCCTTTACC GGTCGACATG GTTCTCATCT CCCTTTGCTT TGGACTCAGC
    ATTGCAACCA TGGTGCAGTG CTTTGGCCAT ATCAGCGGTG GCCACATCAA CCCTGCAGTG
    ACTGTGGCCA TGGTGTGCAC CAGGAAGATC AGCATCGCCA AGTCTGTCTT CTACATCGCA
    GCCCAGTGCC TGGGGGCCAT CATTGGAGCA GGAATCCTCT ATCTGGTCAC ACCTCCCAGT
    GTGGTGGGAG GCCTGGGAGT CACCATGGTT CATGGAAATC TTACCGCTGG TCATGGTCTC
    CTGGTTGAGT TGATAATCAC ATTTCAATTG GTGTTTACTA TCTTTGCCAG CTGTGATTCC
    AAACGGACTG ATGTCACTGG CTCAATAGCT TTAGCAATTG GATTTTCTGT TGCAATTGGA
    CATTTATTTG CAATCAATTA TACTGGTGCC AGCATGAATC CCGCCCGATC CTTTGGACCT
    GCAGTTATCA TGGGAAATTG GGAAAACCAT TGGATATATT GGGTTGGGCC CATCATAGGA
    GCTGTCCTCG CTGGTGGCCT TTATGAGTAT GTCTTCTGTC CAGATGTTGA ATTCAAACGT
    CGTTTTAAAG AAGCCTTCAG CAAAGCTGCC CAGCAAACAA AAGGAAGCTA CATGGAGGTG
    GAGGACAACA GGAGTCAGGT AGAGACGGAT GACCTGATTC TAAAACCTGG AGTGGTGCAT
    GTGATTGACG TTGACCGGGG AGAGGAGAAG AAGGGGAAAG ACCAATCTGG AGAGGTATTG
    TCTTCAGTAT GA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001641.1
    CDS156..1127
    Translation

    Target ORF information:

    RefSeq Version NM_001650.5
    Organism Homo sapiens(Human)
    Definition Homo sapiens aquaporin 4 (AQP4), transcript variant 1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001650.5

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGAGTGACA GACCCACAGC AAGGCGGTGG GGTAAGTGTG GACCTTTGTG TACCAGAGAG 
    AACATCATGG TGGCTTTCAA AGGGGTCTGG ACTCAAGCTT TCTGGAAAGC AGTCACAGCG
    GAATTTCTGG CCATGCTTAT TTTTGTTCTC CTCAGCCTGG GATCCACCAT CAACTGGGGT
    GGAACAGAAA AGCCTTTACC GGTCGACATG GTTCTCATCT CCCTTTGCTT TGGACTCAGC
    ATTGCAACCA TGGTGCAGTG CTTTGGCCAT ATCAGCGGTG GCCACATCAA CCCTGCAGTG
    ACTGTGGCCA TGGTGTGCAC CAGGAAGATC AGCATCGCCA AGTCTGTCTT CTACATCGCA
    GCCCAGTGCC TGGGGGCCAT CATTGGAGCA GGAATCCTCT ATCTGGTCAC ACCTCCCAGT
    GTGGTGGGAG GCCTGGGAGT CACCATGGTT CATGGAAATC TTACCGCTGG TCATGGTCTC
    CTGGTTGAGT TGATAATCAC ATTTCAATTG GTGTTTACTA TCTTTGCCAG CTGTGATTCC
    AAACGGACTG ATGTCACTGG CTCAATAGCT TTAGCAATTG GATTTTCTGT TGCAATTGGA
    CATTTATTTG CAATCAATTA TACTGGTGCC AGCATGAATC CCGCCCGATC CTTTGGACCT
    GCAGTTATCA TGGGAAATTG GGAAAACCAT TGGATATATT GGGTTGGGCC CATCATAGGA
    GCTGTCCTCG CTGGTGGCCT TTATGAGTAT GTCTTCTGTC CAGATGTTGA ATTCAAACGT
    CGTTTTAAAG AAGCCTTCAG CAAAGCTGCC CAGCAAACAA AAGGAAGCTA CATGGAGGTG
    GAGGACAACA GGAGTCAGGT AGAGACGGAT GACCTGATTC TAAAACCTGG AGTGGTGCAT
    GTGATTGACG TTGACCGGGG AGAGGAGAAG AAGGGGAAAG ACCAATCTGG AGAGGTATTG
    TCTTCAGTAT GA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu24057
    Clone ID Related Accession (Same CDS sequence) NM_001650.5 , NM_001650.6 , NM_001650.4 , NM_001650.7
    Accession Version NM_001650.6 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 972bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2017-12-28
    Organism Homo sapiens(human)
    Product aquaporin-4 isoform M1
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HQ901095.1, AK222684.1, DT220791.1, DA244620.1, AC018371.10 and BU687682.1. On Dec 20, 2017 this sequence version replaced NM_001650.5. Transcript Variant: This variant (1, also known as hMIWC2) represents the predominant transcript and encodes two isoforms, which result from the use of alternative in-frame translation termination codons. The shorter isoform (M1) results from translation termination at the upstream UGA stop codon, while the longer isoform (M1x) results from UGA stop codon readthrough to the downstream UAA termination codon. This RefSeq represents the shorter isoform (M1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.43905.1, SRR1803616.132676.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: full length.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGAGTGACA GACCCACAGC AAGGCGGTGG GGTAAGTGTG GACCTTTGTG TACCAGAGAG 
    AACATCATGG TGGCTTTCAA AGGGGTCTGG ACTCAAGCTT TCTGGAAAGC AGTCACAGCG
    GAATTTCTGG CCATGCTTAT TTTTGTTCTC CTCAGCCTGG GATCCACCAT CAACTGGGGT
    GGAACAGAAA AGCCTTTACC GGTCGACATG GTTCTCATCT CCCTTTGCTT TGGACTCAGC
    ATTGCAACCA TGGTGCAGTG CTTTGGCCAT ATCAGCGGTG GCCACATCAA CCCTGCAGTG
    ACTGTGGCCA TGGTGTGCAC CAGGAAGATC AGCATCGCCA AGTCTGTCTT CTACATCGCA
    GCCCAGTGCC TGGGGGCCAT CATTGGAGCA GGAATCCTCT ATCTGGTCAC ACCTCCCAGT
    GTGGTGGGAG GCCTGGGAGT CACCATGGTT CATGGAAATC TTACCGCTGG TCATGGTCTC
    CTGGTTGAGT TGATAATCAC ATTTCAATTG GTGTTTACTA TCTTTGCCAG CTGTGATTCC
    AAACGGACTG ATGTCACTGG CTCAATAGCT TTAGCAATTG GATTTTCTGT TGCAATTGGA
    CATTTATTTG CAATCAATTA TACTGGTGCC AGCATGAATC CCGCCCGATC CTTTGGACCT
    GCAGTTATCA TGGGAAATTG GGAAAACCAT TGGATATATT GGGTTGGGCC CATCATAGGA
    GCTGTCCTCG CTGGTGGCCT TTATGAGTAT GTCTTCTGTC CAGATGTTGA ATTCAAACGT
    CGTTTTAAAG AAGCCTTCAG CAAAGCTGCC CAGCAAACAA AAGGAAGCTA CATGGAGGTG
    GAGGACAACA GGAGTCAGGT AGAGACGGAT GACCTGATTC TAAAACCTGG AGTGGTGCAT
    GTGATTGACG TTGACCGGGG AGAGGAGAAG AAGGGGAAAG ACCAATCTGG AGAGGTATTG
    TCTTCAGTAT GA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001641.1
    CDS115..1086
    Translation

    Target ORF information:

    RefSeq Version NM_001650.6
    Organism Homo sapiens(human)
    Definition Homo sapiens aquaporin 4 (AQP4), transcript variant 1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001650.6

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGAGTGACA GACCCACAGC AAGGCGGTGG GGTAAGTGTG GACCTTTGTG TACCAGAGAG 
    AACATCATGG TGGCTTTCAA AGGGGTCTGG ACTCAAGCTT TCTGGAAAGC AGTCACAGCG
    GAATTTCTGG CCATGCTTAT TTTTGTTCTC CTCAGCCTGG GATCCACCAT CAACTGGGGT
    GGAACAGAAA AGCCTTTACC GGTCGACATG GTTCTCATCT CCCTTTGCTT TGGACTCAGC
    ATTGCAACCA TGGTGCAGTG CTTTGGCCAT ATCAGCGGTG GCCACATCAA CCCTGCAGTG
    ACTGTGGCCA TGGTGTGCAC CAGGAAGATC AGCATCGCCA AGTCTGTCTT CTACATCGCA
    GCCCAGTGCC TGGGGGCCAT CATTGGAGCA GGAATCCTCT ATCTGGTCAC ACCTCCCAGT
    GTGGTGGGAG GCCTGGGAGT CACCATGGTT CATGGAAATC TTACCGCTGG TCATGGTCTC
    CTGGTTGAGT TGATAATCAC ATTTCAATTG GTGTTTACTA TCTTTGCCAG CTGTGATTCC
    AAACGGACTG ATGTCACTGG CTCAATAGCT TTAGCAATTG GATTTTCTGT TGCAATTGGA
    CATTTATTTG CAATCAATTA TACTGGTGCC AGCATGAATC CCGCCCGATC CTTTGGACCT
    GCAGTTATCA TGGGAAATTG GGAAAACCAT TGGATATATT GGGTTGGGCC CATCATAGGA
    GCTGTCCTCG CTGGTGGCCT TTATGAGTAT GTCTTCTGTC CAGATGTTGA ATTCAAACGT
    CGTTTTAAAG AAGCCTTCAG CAAAGCTGCC CAGCAAACAA AAGGAAGCTA CATGGAGGTG
    GAGGACAACA GGAGTCAGGT AGAGACGGAT GACCTGATTC TAAAACCTGG AGTGGTGCAT
    GTGATTGACG TTGACCGGGG AGAGGAGAAG AAGGGGAAAG ACCAATCTGG AGAGGTATTG
    TCTTCAGTAT GA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu24057
    Clone ID Related Accession (Same CDS sequence) NM_001650.5 , NM_001650.6 , NM_001650.4 , NM_001650.7
    Accession Version NM_001650.4 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 972bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2015-03-14
    Organism Homo sapiens(Human)
    Product aquaporin-4 isoform a
    Comment

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGAGTGACA GACCCACAGC AAGGCGGTGG GGTAAGTGTG GACCTTTGTG TACCAGAGAG 
    AACATCATGG TGGCTTTCAA AGGGGTCTGG ACTCAAGCTT TCTGGAAAGC AGTCACAGCG
    GAATTTCTGG CCATGCTTAT TTTTGTTCTC CTCAGCCTGG GATCCACCAT CAACTGGGGT
    GGAACAGAAA AGCCTTTACC GGTCGACATG GTTCTCATCT CCCTTTGCTT TGGACTCAGC
    ATTGCAACCA TGGTGCAGTG CTTTGGCCAT ATCAGCGGTG GCCACATCAA CCCTGCAGTG
    ACTGTGGCCA TGGTGTGCAC CAGGAAGATC AGCATCGCCA AGTCTGTCTT CTACATCGCA
    GCCCAGTGCC TGGGGGCCAT CATTGGAGCA GGAATCCTCT ATCTGGTCAC ACCTCCCAGT
    GTGGTGGGAG GCCTGGGAGT CACCATGGTT CATGGAAATC TTACCGCTGG TCATGGTCTC
    CTGGTTGAGT TGATAATCAC ATTTCAATTG GTGTTTACTA TCTTTGCCAG CTGTGATTCC
    AAACGGACTG ATGTCACTGG CTCAATAGCT TTAGCAATTG GATTTTCTGT TGCAATTGGA
    CATTTATTTG CAATCAATTA TACTGGTGCC AGCATGAATC CCGCCCGATC CTTTGGACCT
    GCAGTTATCA TGGGAAATTG GGAAAACCAT TGGATATATT GGGTTGGGCC CATCATAGGA
    GCTGTCCTCG CTGGTGGCCT TTATGAGTAT GTCTTCTGTC CAGATGTTGA ATTCAAACGT
    CGTTTTAAAG AAGCCTTCAG CAAAGCTGCC CAGCAAACAA AAGGAAGCTA CATGGAGGTG
    GAGGACAACA GGAGTCAGGT AGAGACGGAT GACCTGATTC TAAAACCTGG AGTGGTGCAT
    GTGATTGACG TTGACCGGGG AGAGGAGAAG AAGGGGAAAG ACCAATCTGG AGAGGTATTG
    TCTTCAGTAT GA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001641.1
    Translation

    Target ORF information:

    RefSeq Version NM_001650.4
    Organism Homo sapiens(Human)
    Definition Homo sapiens aquaporin 4 (AQP4), transcript variant a, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001650.4

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGAGTGACA GACCCACAGC AAGGCGGTGG GGTAAGTGTG GACCTTTGTG TACCAGAGAG 
    AACATCATGG TGGCTTTCAA AGGGGTCTGG ACTCAAGCTT TCTGGAAAGC AGTCACAGCG
    GAATTTCTGG CCATGCTTAT TTTTGTTCTC CTCAGCCTGG GATCCACCAT CAACTGGGGT
    GGAACAGAAA AGCCTTTACC GGTCGACATG GTTCTCATCT CCCTTTGCTT TGGACTCAGC
    ATTGCAACCA TGGTGCAGTG CTTTGGCCAT ATCAGCGGTG GCCACATCAA CCCTGCAGTG
    ACTGTGGCCA TGGTGTGCAC CAGGAAGATC AGCATCGCCA AGTCTGTCTT CTACATCGCA
    GCCCAGTGCC TGGGGGCCAT CATTGGAGCA GGAATCCTCT ATCTGGTCAC ACCTCCCAGT
    GTGGTGGGAG GCCTGGGAGT CACCATGGTT CATGGAAATC TTACCGCTGG TCATGGTCTC
    CTGGTTGAGT TGATAATCAC ATTTCAATTG GTGTTTACTA TCTTTGCCAG CTGTGATTCC
    AAACGGACTG ATGTCACTGG CTCAATAGCT TTAGCAATTG GATTTTCTGT TGCAATTGGA
    CATTTATTTG CAATCAATTA TACTGGTGCC AGCATGAATC CCGCCCGATC CTTTGGACCT
    GCAGTTATCA TGGGAAATTG GGAAAACCAT TGGATATATT GGGTTGGGCC CATCATAGGA
    GCTGTCCTCG CTGGTGGCCT TTATGAGTAT GTCTTCTGTC CAGATGTTGA ATTCAAACGT
    CGTTTTAAAG AAGCCTTCAG CAAAGCTGCC CAGCAAACAA AAGGAAGCTA CATGGAGGTG
    GAGGACAACA GGAGTCAGGT AGAGACGGAT GACCTGATTC TAAAACCTGG AGTGGTGCAT
    GTGATTGACG TTGACCGGGG AGAGGAGAAG AAGGGGAAAG ACCAATCTGG AGAGGTATTG
    TCTTCAGTAT GA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu24057
    Clone ID Related Accession (Same CDS sequence) NM_001650.5 , NM_001650.6 , NM_001650.4 , NM_001650.7
    Accession Version NM_001650.7 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 972bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-08-21
    Organism Homo sapiens(human)
    Product aquaporin-4 isoform M1
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HQ901095.1, AK222684.1, DT220791.1, DA244620.1, AC018371.10 and BU687682.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_001650.6. Transcript Variant: This variant (1, also known as hMIWC2) represents the predominant transcript and encodes four isoforms, resulting from the use of two alternative in-frame translation initiation codons and two alternative in-frame translation termination codons. This RefSeq represents isoform M1, which results from the use of the upstream AUG start codon and the upstream UGA stop codon. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.115395.1, SRR1660803.80948.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2147920, SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000383168.9/ ENSP00000372654.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGAGTGACA GACCCACAGC AAGGCGGTGG GGTAAGTGTG GACCTTTGTG TACCAGAGAG 
    AACATCATGG TGGCTTTCAA AGGGGTCTGG ACTCAAGCTT TCTGGAAAGC AGTCACAGCG
    GAATTTCTGG CCATGCTTAT TTTTGTTCTC CTCAGCCTGG GATCCACCAT CAACTGGGGT
    GGAACAGAAA AGCCTTTACC GGTCGACATG GTTCTCATCT CCCTTTGCTT TGGACTCAGC
    ATTGCAACCA TGGTGCAGTG CTTTGGCCAT ATCAGCGGTG GCCACATCAA CCCTGCAGTG
    ACTGTGGCCA TGGTGTGCAC CAGGAAGATC AGCATCGCCA AGTCTGTCTT CTACATCGCA
    GCCCAGTGCC TGGGGGCCAT CATTGGAGCA GGAATCCTCT ATCTGGTCAC ACCTCCCAGT
    GTGGTGGGAG GCCTGGGAGT CACCATGGTT CATGGAAATC TTACCGCTGG TCATGGTCTC
    CTGGTTGAGT TGATAATCAC ATTTCAATTG GTGTTTACTA TCTTTGCCAG CTGTGATTCC
    AAACGGACTG ATGTCACTGG CTCAATAGCT TTAGCAATTG GATTTTCTGT TGCAATTGGA
    CATTTATTTG CAATCAATTA TACTGGTGCC AGCATGAATC CCGCCCGATC CTTTGGACCT
    GCAGTTATCA TGGGAAATTG GGAAAACCAT TGGATATATT GGGTTGGGCC CATCATAGGA
    GCTGTCCTCG CTGGTGGCCT TTATGAGTAT GTCTTCTGTC CAGATGTTGA ATTCAAACGT
    CGTTTTAAAG AAGCCTTCAG CAAAGCTGCC CAGCAAACAA AAGGAAGCTA CATGGAGGTG
    GAGGACAACA GGAGTCAGGT AGAGACGGAT GACCTGATTC TAAAACCTGG AGTGGTGCAT
    GTGATTGACG TTGACCGGGG AGAGGAGAAG AAGGGGAAAG ACCAATCTGG AGAGGTATTG
    TCTTCAGTAT GA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001641.1
    CDS19..990
    Translation

    Target ORF information:

    RefSeq Version NM_001650.7
    Organism Homo sapiens(human)
    Definition Homo sapiens aquaporin 4 (AQP4), transcript variant 1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001650.7

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGAGTGACA GACCCACAGC AAGGCGGTGG GGTAAGTGTG GACCTTTGTG TACCAGAGAG 
    AACATCATGG TGGCTTTCAA AGGGGTCTGG ACTCAAGCTT TCTGGAAAGC AGTCACAGCG
    GAATTTCTGG CCATGCTTAT TTTTGTTCTC CTCAGCCTGG GATCCACCAT CAACTGGGGT
    GGAACAGAAA AGCCTTTACC GGTCGACATG GTTCTCATCT CCCTTTGCTT TGGACTCAGC
    ATTGCAACCA TGGTGCAGTG CTTTGGCCAT ATCAGCGGTG GCCACATCAA CCCTGCAGTG
    ACTGTGGCCA TGGTGTGCAC CAGGAAGATC AGCATCGCCA AGTCTGTCTT CTACATCGCA
    GCCCAGTGCC TGGGGGCCAT CATTGGAGCA GGAATCCTCT ATCTGGTCAC ACCTCCCAGT
    GTGGTGGGAG GCCTGGGAGT CACCATGGTT CATGGAAATC TTACCGCTGG TCATGGTCTC
    CTGGTTGAGT TGATAATCAC ATTTCAATTG GTGTTTACTA TCTTTGCCAG CTGTGATTCC
    AAACGGACTG ATGTCACTGG CTCAATAGCT TTAGCAATTG GATTTTCTGT TGCAATTGGA
    CATTTATTTG CAATCAATTA TACTGGTGCC AGCATGAATC CCGCCCGATC CTTTGGACCT
    GCAGTTATCA TGGGAAATTG GGAAAACCAT TGGATATATT GGGTTGGGCC CATCATAGGA
    GCTGTCCTCG CTGGTGGCCT TTATGAGTAT GTCTTCTGTC CAGATGTTGA ATTCAAACGT
    CGTTTTAAAG AAGCCTTCAG CAAAGCTGCC CAGCAAACAA AAGGAAGCTA CATGGAGGTG
    GAGGACAACA GGAGTCAGGT AGAGACGGAT GACCTGATTC TAAAACCTGG AGTGGTGCAT
    GTGATTGACG TTGACCGGGG AGAGGAGAAG AAGGGGAAAG ACCAATCTGG AGAGGTATTG
    TCTTCAGTAT GA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu102796
    Clone ID Related Accession (Same CDS sequence) NM_001317384.1 , NM_001317384.2
    Accession Version NM_001317384.1 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1059bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2017-05-06
    Organism Homo sapiens(Human)
    Product aquaporin-4 isoform M1x
    Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC018371.10, HQ901095.1, BC030745.1 and BU687682.1. Transcript Variant: This variant (1, also known as hMIWC2) represents the predominant transcript and encodes two isoforms, which result from the use of alternative in-frame translation termination codons. The shorter isoform (M1) results from translation termination at the upstream UGA stop codon (nt 1125-1127), while the longer isoform (M1x) results from UGA stop codon readthrough to the downstream UAA termination codon (nt 1212-1214). This RefSeq represents the longer, C-terminally extended isoform. As the UGA stop codon has been reported to specify several alternative amino acids (tryptophan, cysteine, arginine and serine), its location in the longer isoform is denoted by an 'X'. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.43905.1, SRR1803616.132676.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2147920, SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## stop codon readthrough :: PMID: 25013167 ##RefSeq-Attributes-END## COMPLETENESS: full length.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGAGTGACA GACCCACAGC AAGGCGGTGG GGTAAGTGTG GACCTTTGTG TACCAGAGAG 
    AACATCATGG TGGCTTTCAA AGGGGTCTGG ACTCAAGCTT TCTGGAAAGC AGTCACAGCG
    GAATTTCTGG CCATGCTTAT TTTTGTTCTC CTCAGCCTGG GATCCACCAT CAACTGGGGT
    GGAACAGAAA AGCCTTTACC GGTCGACATG GTTCTCATCT CCCTTTGCTT TGGACTCAGC
    ATTGCAACCA TGGTGCAGTG CTTTGGCCAT ATCAGCGGTG GCCACATCAA CCCTGCAGTG
    ACTGTGGCCA TGGTGTGCAC CAGGAAGATC AGCATCGCCA AGTCTGTCTT CTACATCGCA
    GCCCAGTGCC TGGGGGCCAT CATTGGAGCA GGAATCCTCT ATCTGGTCAC ACCTCCCAGT
    GTGGTGGGAG GCCTGGGAGT CACCATGGTT CATGGAAATC TTACCGCTGG TCATGGTCTC
    CTGGTTGAGT TGATAATCAC ATTTCAATTG GTGTTTACTA TCTTTGCCAG CTGTGATTCC
    AAACGGACTG ATGTCACTGG CTCAATAGCT TTAGCAATTG GATTTTCTGT TGCAATTGGA
    CATTTATTTG CAATCAATTA TACTGGTGCC AGCATGAATC CCGCCCGATC CTTTGGACCT
    GCAGTTATCA TGGGAAATTG GGAAAACCAT TGGATATATT GGGTTGGGCC CATCATAGGA
    GCTGTCCTCG CTGGTGGCCT TTATGAGTAT GTCTTCTGTC CAGATGTTGA ATTCAAACGT
    CGTTTTAAAG AAGCCTTCAG CAAAGCTGCC CAGCAAACAA AAGGAAGCTA CATGGAGGTG
    GAGGACAACA GGAGTCAGGT AGAGACGGAT GACCTGATTC TAAAACCTGG AGTGGTGCAT
    GTGATTGACG TTGACCGGGG AGAGGAGAAG AAGGGGAAAG ACCAATCTGG AGAGGTATTG
    TCTTCAGTAT GACTAGAAGA TCGCACTGAA AGCAGACAAG ACTCCTTAGA ACTGTCCTCA
    GATTTCCTTC CACCCATTAA GGAAACAGAT TTGTTATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001304313.1
    CDS156..1214
    Translation

    Target ORF information:

    RefSeq Version NM_001317384.1
    Organism Homo sapiens(Human)
    Definition Homo sapiens aquaporin 4 (AQP4), transcript variant 1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001317384.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGAGTGACA GACCCACAGC AAGGCGGTGG GGTAAGTGTG GACCTTTGTG TACCAGAGAG 
    AACATCATGG TGGCTTTCAA AGGGGTCTGG ACTCAAGCTT TCTGGAAAGC AGTCACAGCG
    GAATTTCTGG CCATGCTTAT TTTTGTTCTC CTCAGCCTGG GATCCACCAT CAACTGGGGT
    GGAACAGAAA AGCCTTTACC GGTCGACATG GTTCTCATCT CCCTTTGCTT TGGACTCAGC
    ATTGCAACCA TGGTGCAGTG CTTTGGCCAT ATCAGCGGTG GCCACATCAA CCCTGCAGTG
    ACTGTGGCCA TGGTGTGCAC CAGGAAGATC AGCATCGCCA AGTCTGTCTT CTACATCGCA
    GCCCAGTGCC TGGGGGCCAT CATTGGAGCA GGAATCCTCT ATCTGGTCAC ACCTCCCAGT
    GTGGTGGGAG GCCTGGGAGT CACCATGGTT CATGGAAATC TTACCGCTGG TCATGGTCTC
    CTGGTTGAGT TGATAATCAC ATTTCAATTG GTGTTTACTA TCTTTGCCAG CTGTGATTCC
    AAACGGACTG ATGTCACTGG CTCAATAGCT TTAGCAATTG GATTTTCTGT TGCAATTGGA
    CATTTATTTG CAATCAATTA TACTGGTGCC AGCATGAATC CCGCCCGATC CTTTGGACCT
    GCAGTTATCA TGGGAAATTG GGAAAACCAT TGGATATATT GGGTTGGGCC CATCATAGGA
    GCTGTCCTCG CTGGTGGCCT TTATGAGTAT GTCTTCTGTC CAGATGTTGA ATTCAAACGT
    CGTTTTAAAG AAGCCTTCAG CAAAGCTGCC CAGCAAACAA AAGGAAGCTA CATGGAGGTG
    GAGGACAACA GGAGTCAGGT AGAGACGGAT GACCTGATTC TAAAACCTGG AGTGGTGCAT
    GTGATTGACG TTGACCGGGG AGAGGAGAAG AAGGGGAAAG ACCAATCTGG AGAGGTATTG
    TCTTCAGTAT GACTAGAAGA TCGCACTGAA AGCAGACAAG ACTCCTTAGA ACTGTCCTCA
    GATTTCCTTC CACCCATTAA GGAAACAGAT TTGTTATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu102796
    Clone ID Related Accession (Same CDS sequence) NM_001317384.1 , NM_001317384.2
    Accession Version NM_001317384.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1059bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-08-20
    Organism Homo sapiens(human)
    Product aquaporin-4 isoform M1x
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HQ901095.1, AK222684.1, DT220791.1, DA244620.1, AC018371.10 and BU687682.1. On Dec 20, 2017 this sequence version replaced NM_001317384.1. Transcript Variant: This variant (1, also known as hMIWC2) represents the predominant transcript and encodes four isoforms, resulting from the use of two alternative in-frame translation initiation codons and two alternative in-frame translation termination codons. This RefSeq represents the longest, C-terminally extended isoform (M1x, also known as M1ex), which results from the use of the upstream AUG start codon and readthrough of the upstream UGA stop codon to the downstream UAA stop codon. As the UGA stop codon has been reported to specify several alternative amino acids (tryptophan, cysteine, arginine and serine), its location in this isoform is denoted by an 'X'. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.43905.1, SRR1803616.132676.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2147920, SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## stop codon readthrough :: PMID: 25013167, 28206694 ##RefSeq-Attributes-END## COMPLETENESS: full length.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGAGTGACA GACCCACAGC AAGGCGGTGG GGTAAGTGTG GACCTTTGTG TACCAGAGAG 
    AACATCATGG TGGCTTTCAA AGGGGTCTGG ACTCAAGCTT TCTGGAAAGC AGTCACAGCG
    GAATTTCTGG CCATGCTTAT TTTTGTTCTC CTCAGCCTGG GATCCACCAT CAACTGGGGT
    GGAACAGAAA AGCCTTTACC GGTCGACATG GTTCTCATCT CCCTTTGCTT TGGACTCAGC
    ATTGCAACCA TGGTGCAGTG CTTTGGCCAT ATCAGCGGTG GCCACATCAA CCCTGCAGTG
    ACTGTGGCCA TGGTGTGCAC CAGGAAGATC AGCATCGCCA AGTCTGTCTT CTACATCGCA
    GCCCAGTGCC TGGGGGCCAT CATTGGAGCA GGAATCCTCT ATCTGGTCAC ACCTCCCAGT
    GTGGTGGGAG GCCTGGGAGT CACCATGGTT CATGGAAATC TTACCGCTGG TCATGGTCTC
    CTGGTTGAGT TGATAATCAC ATTTCAATTG GTGTTTACTA TCTTTGCCAG CTGTGATTCC
    AAACGGACTG ATGTCACTGG CTCAATAGCT TTAGCAATTG GATTTTCTGT TGCAATTGGA
    CATTTATTTG CAATCAATTA TACTGGTGCC AGCATGAATC CCGCCCGATC CTTTGGACCT
    GCAGTTATCA TGGGAAATTG GGAAAACCAT TGGATATATT GGGTTGGGCC CATCATAGGA
    GCTGTCCTCG CTGGTGGCCT TTATGAGTAT GTCTTCTGTC CAGATGTTGA ATTCAAACGT
    CGTTTTAAAG AAGCCTTCAG CAAAGCTGCC CAGCAAACAA AAGGAAGCTA CATGGAGGTG
    GAGGACAACA GGAGTCAGGT AGAGACGGAT GACCTGATTC TAAAACCTGG AGTGGTGCAT
    GTGATTGACG TTGACCGGGG AGAGGAGAAG AAGGGGAAAG ACCAATCTGG AGAGGTATTG
    TCTTCAGTAT GACTAGAAGA TCGCACTGAA AGCAGACAAG ACTCCTTAGA ACTGTCCTCA
    GATTTCCTTC CACCCATTAA GGAAACAGAT TTGTTATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001304313.1
    CDS115..1173
    Translation

    Target ORF information:

    RefSeq Version NM_001317384.2
    Organism Homo sapiens(human)
    Definition Homo sapiens aquaporin 4 (AQP4), transcript variant 1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001317384.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGAGTGACA GACCCACAGC AAGGCGGTGG GGTAAGTGTG GACCTTTGTG TACCAGAGAG 
    AACATCATGG TGGCTTTCAA AGGGGTCTGG ACTCAAGCTT TCTGGAAAGC AGTCACAGCG
    GAATTTCTGG CCATGCTTAT TTTTGTTCTC CTCAGCCTGG GATCCACCAT CAACTGGGGT
    GGAACAGAAA AGCCTTTACC GGTCGACATG GTTCTCATCT CCCTTTGCTT TGGACTCAGC
    ATTGCAACCA TGGTGCAGTG CTTTGGCCAT ATCAGCGGTG GCCACATCAA CCCTGCAGTG
    ACTGTGGCCA TGGTGTGCAC CAGGAAGATC AGCATCGCCA AGTCTGTCTT CTACATCGCA
    GCCCAGTGCC TGGGGGCCAT CATTGGAGCA GGAATCCTCT ATCTGGTCAC ACCTCCCAGT
    GTGGTGGGAG GCCTGGGAGT CACCATGGTT CATGGAAATC TTACCGCTGG TCATGGTCTC
    CTGGTTGAGT TGATAATCAC ATTTCAATTG GTGTTTACTA TCTTTGCCAG CTGTGATTCC
    AAACGGACTG ATGTCACTGG CTCAATAGCT TTAGCAATTG GATTTTCTGT TGCAATTGGA
    CATTTATTTG CAATCAATTA TACTGGTGCC AGCATGAATC CCGCCCGATC CTTTGGACCT
    GCAGTTATCA TGGGAAATTG GGAAAACCAT TGGATATATT GGGTTGGGCC CATCATAGGA
    GCTGTCCTCG CTGGTGGCCT TTATGAGTAT GTCTTCTGTC CAGATGTTGA ATTCAAACGT
    CGTTTTAAAG AAGCCTTCAG CAAAGCTGCC CAGCAAACAA AAGGAAGCTA CATGGAGGTG
    GAGGACAACA GGAGTCAGGT AGAGACGGAT GACCTGATTC TAAAACCTGG AGTGGTGCAT
    GTGATTGACG TTGACCGGGG AGAGGAGAAG AAGGGGAAAG ACCAATCTGG AGAGGTATTG
    TCTTCAGTAT GACTAGAAGA TCGCACTGAA AGCAGACAAG ACTCCTTAGA ACTGTCCTCA
    GATTTCCTTC CACCCATTAA GGAAACAGAT TTGTTATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu56344
    Clone ID Related Accession (Same CDS sequence) XM_011525942.2 , XM_011525942.3
    Accession Version XM_011525942.2 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 951bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2016-06-05
    Organism Homo sapiens(human)
    Product aquaporin-4 isoform X1
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000018.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011525942.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGTTCGAAA TTAAGTGTGG ACCTTTGTGT ACCAGAGAGA ACATCATGGT GGCTTTCAAA 
    GGGGTCTGGA CTCAAGCTTT CTGGAAAGCA GTCACAGCGG AATTTCTGGC CATGCTTATT
    TTTGTTCTCC TCAGCCTGGG ATCCACCATC AACTGGGGTG GAACAGAAAA GCCTTTACCG
    GTCGACATGG TTCTCATCTC CCTTTGCTTT GGACTCAGCA TTGCAACCAT GGTGCAGTGC
    TTTGGCCATA TCAGCGGTGG CCACATCAAC CCTGCAGTGA CTGTGGCCAT GGTGTGCACC
    AGGAAGATCA GCATCGCCAA GTCTGTCTTC TACATCGCAG CCCAGTGCCT GGGGGCCATC
    ATTGGAGCAG GAATCCTCTA TCTGGTCACA CCTCCCAGTG TGGTGGGAGG CCTGGGAGTC
    ACCATGGTTC ATGGAAATCT TACCGCTGGT CATGGTCTCC TGGTTGAGTT GATAATCACA
    TTTCAATTGG TGTTTACTAT CTTTGCCAGC TGTGATTCCA AACGGACTGA TGTCACTGGC
    TCAATAGCTT TAGCAATTGG ATTTTCTGTT GCAATTGGAC ATTTATTTGC AATCAATTAT
    ACTGGTGCCA GCATGAATCC CGCCCGATCC TTTGGACCTG CAGTTATCAT GGGAAATTGG
    GAAAACCATT GGATATATTG GGTTGGGCCC ATCATAGGAG CTGTCCTCGC TGGTGGCCTT
    TATGAGTATG TCTTCTGTCC AGATGTTGAA TTCAAACGTC GTTTTAAAGA AGCCTTCAGC
    AAAGCTGCCC AGCAAACAAA AGGAAGCTAC ATGGAGGTGG AGGACAACAG GAGTCAGGTA
    GAGACGGATG ACCTGATTCT AAAACCTGGA GTGGTGCATG TGATTGACGT TGACCGGGGA
    GAGGAGAAGA AGGGGAAAGA CCAATCTGGA GAGGTATTGT CTTCAGTATG A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_011524244.1
    CDS219..1169
    Translation

    Target ORF information:

    RefSeq Version XM_011525942.2
    Organism Homo sapiens(human)
    Definition Homo sapiens aquaporin 4 (AQP4), transcript variant X1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_011525942.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGTTCGAAA TTAAGTGTGG ACCTTTGTGT ACCAGAGAGA ACATCATGGT GGCTTTCAAA 
    GGGGTCTGGA CTCAAGCTTT CTGGAAAGCA GTCACAGCGG AATTTCTGGC CATGCTTATT
    TTTGTTCTCC TCAGCCTGGG ATCCACCATC AACTGGGGTG GAACAGAAAA GCCTTTACCG
    GTCGACATGG TTCTCATCTC CCTTTGCTTT GGACTCAGCA TTGCAACCAT GGTGCAGTGC
    TTTGGCCATA TCAGCGGTGG CCACATCAAC CCTGCAGTGA CTGTGGCCAT GGTGTGCACC
    AGGAAGATCA GCATCGCCAA GTCTGTCTTC TACATCGCAG CCCAGTGCCT GGGGGCCATC
    ATTGGAGCAG GAATCCTCTA TCTGGTCACA CCTCCCAGTG TGGTGGGAGG CCTGGGAGTC
    ACCATGGTTC ATGGAAATCT TACCGCTGGT CATGGTCTCC TGGTTGAGTT GATAATCACA
    TTTCAATTGG TGTTTACTAT CTTTGCCAGC TGTGATTCCA AACGGACTGA TGTCACTGGC
    TCAATAGCTT TAGCAATTGG ATTTTCTGTT GCAATTGGAC ATTTATTTGC AATCAATTAT
    ACTGGTGCCA GCATGAATCC CGCCCGATCC TTTGGACCTG CAGTTATCAT GGGAAATTGG
    GAAAACCATT GGATATATTG GGTTGGGCCC ATCATAGGAG CTGTCCTCGC TGGTGGCCTT
    TATGAGTATG TCTTCTGTCC AGATGTTGAA TTCAAACGTC GTTTTAAAGA AGCCTTCAGC
    AAAGCTGCCC AGCAAACAAA AGGAAGCTAC ATGGAGGTGG AGGACAACAG GAGTCAGGTA
    GAGACGGATG ACCTGATTCT AAAACCTGGA GTGGTGCATG TGATTGACGT TGACCGGGGA
    GAGGAGAAGA AGGGGAAAGA CCAATCTGGA GAGGTATTGT CTTCAGTATG A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu56344
    Clone ID Related Accession (Same CDS sequence) XM_011525942.2 , XM_011525942.3
    Accession Version XM_011525942.3 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 951bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-05
    Organism Homo sapiens(human)
    Product aquaporin-4 isoform X1
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000018.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011525942.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGTTCGAAA TTAAGTGTGG ACCTTTGTGT ACCAGAGAGA ACATCATGGT GGCTTTCAAA 
    GGGGTCTGGA CTCAAGCTTT CTGGAAAGCA GTCACAGCGG AATTTCTGGC CATGCTTATT
    TTTGTTCTCC TCAGCCTGGG ATCCACCATC AACTGGGGTG GAACAGAAAA GCCTTTACCG
    GTCGACATGG TTCTCATCTC CCTTTGCTTT GGACTCAGCA TTGCAACCAT GGTGCAGTGC
    TTTGGCCATA TCAGCGGTGG CCACATCAAC CCTGCAGTGA CTGTGGCCAT GGTGTGCACC
    AGGAAGATCA GCATCGCCAA GTCTGTCTTC TACATCGCAG CCCAGTGCCT GGGGGCCATC
    ATTGGAGCAG GAATCCTCTA TCTGGTCACA CCTCCCAGTG TGGTGGGAGG CCTGGGAGTC
    ACCATGGTTC ATGGAAATCT TACCGCTGGT CATGGTCTCC TGGTTGAGTT GATAATCACA
    TTTCAATTGG TGTTTACTAT CTTTGCCAGC TGTGATTCCA AACGGACTGA TGTCACTGGC
    TCAATAGCTT TAGCAATTGG ATTTTCTGTT GCAATTGGAC ATTTATTTGC AATCAATTAT
    ACTGGTGCCA GCATGAATCC CGCCCGATCC TTTGGACCTG CAGTTATCAT GGGAAATTGG
    GAAAACCATT GGATATATTG GGTTGGGCCC ATCATAGGAG CTGTCCTCGC TGGTGGCCTT
    TATGAGTATG TCTTCTGTCC AGATGTTGAA TTCAAACGTC GTTTTAAAGA AGCCTTCAGC
    AAAGCTGCCC AGCAAACAAA AGGAAGCTAC ATGGAGGTGG AGGACAACAG GAGTCAGGTA
    GAGACGGATG ACCTGATTCT AAAACCTGGA GTGGTGCATG TGATTGACGT TGACCGGGGA
    GAGGAGAAGA AGGGGAAAGA CCAATCTGGA GAGGTATTGT CTTCAGTATG A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_011524244.1
    CDS219..1169
    Translation

    Target ORF information:

    RefSeq Version XM_011525942.3
    Organism Homo sapiens(human)
    Definition Homo sapiens aquaporin 4 (AQP4), transcript variant X1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_011525942.3

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGTTCGAAA TTAAGTGTGG ACCTTTGTGT ACCAGAGAGA ACATCATGGT GGCTTTCAAA 
    GGGGTCTGGA CTCAAGCTTT CTGGAAAGCA GTCACAGCGG AATTTCTGGC CATGCTTATT
    TTTGTTCTCC TCAGCCTGGG ATCCACCATC AACTGGGGTG GAACAGAAAA GCCTTTACCG
    GTCGACATGG TTCTCATCTC CCTTTGCTTT GGACTCAGCA TTGCAACCAT GGTGCAGTGC
    TTTGGCCATA TCAGCGGTGG CCACATCAAC CCTGCAGTGA CTGTGGCCAT GGTGTGCACC
    AGGAAGATCA GCATCGCCAA GTCTGTCTTC TACATCGCAG CCCAGTGCCT GGGGGCCATC
    ATTGGAGCAG GAATCCTCTA TCTGGTCACA CCTCCCAGTG TGGTGGGAGG CCTGGGAGTC
    ACCATGGTTC ATGGAAATCT TACCGCTGGT CATGGTCTCC TGGTTGAGTT GATAATCACA
    TTTCAATTGG TGTTTACTAT CTTTGCCAGC TGTGATTCCA AACGGACTGA TGTCACTGGC
    TCAATAGCTT TAGCAATTGG ATTTTCTGTT GCAATTGGAC ATTTATTTGC AATCAATTAT
    ACTGGTGCCA GCATGAATCC CGCCCGATCC TTTGGACCTG CAGTTATCAT GGGAAATTGG
    GAAAACCATT GGATATATTG GGTTGGGCCC ATCATAGGAG CTGTCCTCGC TGGTGGCCTT
    TATGAGTATG TCTTCTGTCC AGATGTTGAA TTCAAACGTC GTTTTAAAGA AGCCTTCAGC
    AAAGCTGCCC AGCAAACAAA AGGAAGCTAC ATGGAGGTGG AGGACAACAG GAGTCAGGTA
    GAGACGGATG ACCTGATTCT AAAACCTGGA GTGGTGCATG TGATTGACGT TGACCGGGGA
    GAGGAGAAGA AGGGGAAAGA CCAATCTGGA GAGGTATTGT CTTCAGTATG A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu102800
    Clone ID Related Accession (Same CDS sequence) NM_001317387.1 , NM_001317387.2
    Accession Version NM_001317387.1 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 891bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2017-05-06
    Organism Homo sapiens(Human)
    Product aquaporin-4 isoform delta4
    Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC018371.10, HQ901095.1, KF055862.1, BC030745.1 and BU687682.1. Transcript Variant: This variant (3) lacks an in-frame coding exon compared to variant 1, and encodes a shorter isoform (delta4) missing an internal protein segment compared to isoform M1. This isoform exhibits no water transport properties, downregulates the expression and water channel activity of the full-length isoform; thus, appears to function as a regulator of water permeability (PMID:24356448). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.13146.1, SRR1660807.149989.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2147920, SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGAGTGACA GACCCACAGC AAGGCGGTGG GGTAAGTGTG GACCTTTGTG TACCAGAGAG 
    AACATCATGG TGGCTTTCAA AGGGGTCTGG ACTCAAGCTT TCTGGAAAGC AGTCACAGCG
    GAATTTCTGG CCATGCTTAT TTTTGTTCTC CTCAGCCTGG GATCCACCAT CAACTGGGGT
    GGAACAGAAA AGCCTTTACC GGTCGACATG GTTCTCATCT CCCTTTGCTT TGGACTCAGC
    ATTGCAACCA TGGTGCAGTG CTTTGGCCAT ATCAGCGGTG GCCACATCAA CCCTGCAGTG
    ACTGTGGCCA TGGTGTGCAC CAGGAAGATC AGCATCGCCA AGTCTGTCTT CTACATCGCA
    GCCCAGTGCC TGGGGGCCAT CATTGGAGCA GGAATCCTCT ATCTGGTCAC ACCTCCCAGT
    GTGGTGGGAG GCCTGGGAGT CACCATGGTT CATGGAAATC TTACCGCTGG TCATGGTCTC
    CTGGTTGAGT TGATAATCAC ATTTCAATTG GTGTTTACTA TCTTTGCCAG CTGTGATTCC
    AAACGGACTG ATGTCACTGG CTCAATAGCT TTAGCAATTG GATTTTCTGT TGCAATTGGA
    CATTTATTTG CAATATATTG GGTTGGGCCC ATCATAGGAG CTGTCCTCGC TGGTGGCCTT
    TATGAGTATG TCTTCTGTCC AGATGTTGAA TTCAAACGTC GTTTTAAAGA AGCCTTCAGC
    AAAGCTGCCC AGCAAACAAA AGGAAGCTAC ATGGAGGTGG AGGACAACAG GAGTCAGGTA
    GAGACGGATG ACCTGATTCT AAAACCTGGA GTGGTGCATG TGATTGACGT TGACCGGGGA
    GAGGAGAAGA AGGGGAAAGA CCAATCTGGA GAGGTATTGT CTTCAGTATG A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001304316.1
    CDS156..1046
    Translation

    Target ORF information:

    RefSeq Version NM_001317387.1
    Organism Homo sapiens(Human)
    Definition Homo sapiens aquaporin 4 (AQP4), transcript variant 3, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001317387.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGAGTGACA GACCCACAGC AAGGCGGTGG GGTAAGTGTG GACCTTTGTG TACCAGAGAG 
    AACATCATGG TGGCTTTCAA AGGGGTCTGG ACTCAAGCTT TCTGGAAAGC AGTCACAGCG
    GAATTTCTGG CCATGCTTAT TTTTGTTCTC CTCAGCCTGG GATCCACCAT CAACTGGGGT
    GGAACAGAAA AGCCTTTACC GGTCGACATG GTTCTCATCT CCCTTTGCTT TGGACTCAGC
    ATTGCAACCA TGGTGCAGTG CTTTGGCCAT ATCAGCGGTG GCCACATCAA CCCTGCAGTG
    ACTGTGGCCA TGGTGTGCAC CAGGAAGATC AGCATCGCCA AGTCTGTCTT CTACATCGCA
    GCCCAGTGCC TGGGGGCCAT CATTGGAGCA GGAATCCTCT ATCTGGTCAC ACCTCCCAGT
    GTGGTGGGAG GCCTGGGAGT CACCATGGTT CATGGAAATC TTACCGCTGG TCATGGTCTC
    CTGGTTGAGT TGATAATCAC ATTTCAATTG GTGTTTACTA TCTTTGCCAG CTGTGATTCC
    AAACGGACTG ATGTCACTGG CTCAATAGCT TTAGCAATTG GATTTTCTGT TGCAATTGGA
    CATTTATTTG CAATATATTG GGTTGGGCCC ATCATAGGAG CTGTCCTCGC TGGTGGCCTT
    TATGAGTATG TCTTCTGTCC AGATGTTGAA TTCAAACGTC GTTTTAAAGA AGCCTTCAGC
    AAAGCTGCCC AGCAAACAAA AGGAAGCTAC ATGGAGGTGG AGGACAACAG GAGTCAGGTA
    GAGACGGATG ACCTGATTCT AAAACCTGGA GTGGTGCATG TGATTGACGT TGACCGGGGA
    GAGGAGAAGA AGGGGAAAGA CCAATCTGGA GAGGTATTGT CTTCAGTATG A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu102800
    Clone ID Related Accession (Same CDS sequence) NM_001317387.1 , NM_001317387.2
    Accession Version NM_001317387.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 891bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-08-20
    Organism Homo sapiens(human)
    Product aquaporin-4 isoform delta4
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HQ901095.1, AK222684.1, DT220791.1, DA244620.1, AC018371.10 and BU687682.1. On Dec 20, 2017 this sequence version replaced NM_001317387.1. Transcript Variant: This variant (3) lacks an in-frame coding exon compared to variant 1, and encodes a shorter isoform (delta4) missing an internal protein segment compared to isoform M1. This isoform exhibits no water transport properties, and downregulates the expression and water channel activity of isoform M1; thus, appears to function as a regulator of water permeability (PMID:24356448). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.13146.1, SRR1660807.149989.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2147920, SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGAGTGACA GACCCACAGC AAGGCGGTGG GGTAAGTGTG GACCTTTGTG TACCAGAGAG 
    AACATCATGG TGGCTTTCAA AGGGGTCTGG ACTCAAGCTT TCTGGAAAGC AGTCACAGCG
    GAATTTCTGG CCATGCTTAT TTTTGTTCTC CTCAGCCTGG GATCCACCAT CAACTGGGGT
    GGAACAGAAA AGCCTTTACC GGTCGACATG GTTCTCATCT CCCTTTGCTT TGGACTCAGC
    ATTGCAACCA TGGTGCAGTG CTTTGGCCAT ATCAGCGGTG GCCACATCAA CCCTGCAGTG
    ACTGTGGCCA TGGTGTGCAC CAGGAAGATC AGCATCGCCA AGTCTGTCTT CTACATCGCA
    GCCCAGTGCC TGGGGGCCAT CATTGGAGCA GGAATCCTCT ATCTGGTCAC ACCTCCCAGT
    GTGGTGGGAG GCCTGGGAGT CACCATGGTT CATGGAAATC TTACCGCTGG TCATGGTCTC
    CTGGTTGAGT TGATAATCAC ATTTCAATTG GTGTTTACTA TCTTTGCCAG CTGTGATTCC
    AAACGGACTG ATGTCACTGG CTCAATAGCT TTAGCAATTG GATTTTCTGT TGCAATTGGA
    CATTTATTTG CAATATATTG GGTTGGGCCC ATCATAGGAG CTGTCCTCGC TGGTGGCCTT
    TATGAGTATG TCTTCTGTCC AGATGTTGAA TTCAAACGTC GTTTTAAAGA AGCCTTCAGC
    AAAGCTGCCC AGCAAACAAA AGGAAGCTAC ATGGAGGTGG AGGACAACAG GAGTCAGGTA
    GAGACGGATG ACCTGATTCT AAAACCTGGA GTGGTGCATG TGATTGACGT TGACCGGGGA
    GAGGAGAAGA AGGGGAAAGA CCAATCTGGA GAGGTATTGT CTTCAGTATG A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001304316.1
    CDS115..1005
    Translation

    Target ORF information:

    RefSeq Version NM_001317387.2
    Organism Homo sapiens(human)
    Definition Homo sapiens aquaporin 4 (AQP4), transcript variant 3, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001317387.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGAGTGACA GACCCACAGC AAGGCGGTGG GGTAAGTGTG GACCTTTGTG TACCAGAGAG 
    AACATCATGG TGGCTTTCAA AGGGGTCTGG ACTCAAGCTT TCTGGAAAGC AGTCACAGCG
    GAATTTCTGG CCATGCTTAT TTTTGTTCTC CTCAGCCTGG GATCCACCAT CAACTGGGGT
    GGAACAGAAA AGCCTTTACC GGTCGACATG GTTCTCATCT CCCTTTGCTT TGGACTCAGC
    ATTGCAACCA TGGTGCAGTG CTTTGGCCAT ATCAGCGGTG GCCACATCAA CCCTGCAGTG
    ACTGTGGCCA TGGTGTGCAC CAGGAAGATC AGCATCGCCA AGTCTGTCTT CTACATCGCA
    GCCCAGTGCC TGGGGGCCAT CATTGGAGCA GGAATCCTCT ATCTGGTCAC ACCTCCCAGT
    GTGGTGGGAG GCCTGGGAGT CACCATGGTT CATGGAAATC TTACCGCTGG TCATGGTCTC
    CTGGTTGAGT TGATAATCAC ATTTCAATTG GTGTTTACTA TCTTTGCCAG CTGTGATTCC
    AAACGGACTG ATGTCACTGG CTCAATAGCT TTAGCAATTG GATTTTCTGT TGCAATTGGA
    CATTTATTTG CAATATATTG GGTTGGGCCC ATCATAGGAG CTGTCCTCGC TGGTGGCCTT
    TATGAGTATG TCTTCTGTCC AGATGTTGAA TTCAAACGTC GTTTTAAAGA AGCCTTCAGC
    AAAGCTGCCC AGCAAACAAA AGGAAGCTAC ATGGAGGTGG AGGACAACAG GAGTCAGGTA
    GAGACGGATG ACCTGATTCT AAAACCTGGA GTGGTGCATG TGATTGACGT TGACCGGGGA
    GAGGAGAAGA AGGGGAAAGA CCAATCTGGA GAGGTATTGT CTTCAGTATG A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu106841
    Clone ID Related Accession (Same CDS sequence) NM_001364287.1 , NM_001364289.1
    Accession Version NM_001364287.1 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 993bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-08-20
    Organism Homo sapiens(human)
    Product aquaporin-4 isoform M23x
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HQ901095.1, AK222684.1, DT220791.1, DA244620.1, AC018371.10 and BU687682.1. Transcript Variant: This variant (1, also known as hMIWC2) represents the predominant transcript and encodes four isoforms, resulting from the use of two alternative in-frame translation initiation codons and two alternative in-frame translation termination codons. This RefSeq represents a C-terminally extended isoform (M23x, also known as M23ex), which results from the use of the downstream in-frame AUG start codon and readthrough of the upstream UGA stop codon to the downstream UAA stop codon. As the UGA stop codon has been reported to specify several alternative amino acids (tryptophan, cysteine, arginine and serine), its location in this isoform is denoted by an 'X'. An alternatively spliced transcript variant (NM_001364289.1) encodes the same isoform. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.43905.1, SRR1803616.132676.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: experimental evidence (PMID:20007705) stop codon readthrough :: PMID: 28206694 ##RefSeq-Attributes-END## COMPLETENESS: full length.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGGTGGCTT TCAAAGGGGT CTGGACTCAA GCTTTCTGGA AAGCAGTCAC AGCGGAATTT 
    CTGGCCATGC TTATTTTTGT TCTCCTCAGC CTGGGATCCA CCATCAACTG GGGTGGAACA
    GAAAAGCCTT TACCGGTCGA CATGGTTCTC ATCTCCCTTT GCTTTGGACT CAGCATTGCA
    ACCATGGTGC AGTGCTTTGG CCATATCAGC GGTGGCCACA TCAACCCTGC AGTGACTGTG
    GCCATGGTGT GCACCAGGAA GATCAGCATC GCCAAGTCTG TCTTCTACAT CGCAGCCCAG
    TGCCTGGGGG CCATCATTGG AGCAGGAATC CTCTATCTGG TCACACCTCC CAGTGTGGTG
    GGAGGCCTGG GAGTCACCAT GGTTCATGGA AATCTTACCG CTGGTCATGG TCTCCTGGTT
    GAGTTGATAA TCACATTTCA ATTGGTGTTT ACTATCTTTG CCAGCTGTGA TTCCAAACGG
    ACTGATGTCA CTGGCTCAAT AGCTTTAGCA ATTGGATTTT CTGTTGCAAT TGGACATTTA
    TTTGCAATCA ATTATACTGG TGCCAGCATG AATCCCGCCC GATCCTTTGG ACCTGCAGTT
    ATCATGGGAA ATTGGGAAAA CCATTGGATA TATTGGGTTG GGCCCATCAT AGGAGCTGTC
    CTCGCTGGTG GCCTTTATGA GTATGTCTTC TGTCCAGATG TTGAATTCAA ACGTCGTTTT
    AAAGAAGCCT TCAGCAAAGC TGCCCAGCAA ACAAAAGGAA GCTACATGGA GGTGGAGGAC
    AACAGGAGTC AGGTAGAGAC GGATGACCTG ATTCTAAAAC CTGGAGTGGT GCATGTGATT
    GACGTTGACC GGGGAGAGGA GAAGAAGGGG AAAGACCAAT CTGGAGAGGT ATTGTCTTCA
    GTATGACTAG AAGATCGCAC TGAAAGCAGA CAAGACTCCT TAGAACTGTC CTCAGATTTC
    CTTCCACCCA TTAAGGAAAC AGATTTGTTA TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001351216.1
    CDS181..1173
    Translation

    Target ORF information:

    RefSeq Version NM_001364287.1
    Organism Homo sapiens(human)
    Definition Homo sapiens aquaporin 4 (AQP4), transcript variant 1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001364287.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGGTGGCTT TCAAAGGGGT CTGGACTCAA GCTTTCTGGA AAGCAGTCAC AGCGGAATTT 
    CTGGCCATGC TTATTTTTGT TCTCCTCAGC CTGGGATCCA CCATCAACTG GGGTGGAACA
    GAAAAGCCTT TACCGGTCGA CATGGTTCTC ATCTCCCTTT GCTTTGGACT CAGCATTGCA
    ACCATGGTGC AGTGCTTTGG CCATATCAGC GGTGGCCACA TCAACCCTGC AGTGACTGTG
    GCCATGGTGT GCACCAGGAA GATCAGCATC GCCAAGTCTG TCTTCTACAT CGCAGCCCAG
    TGCCTGGGGG CCATCATTGG AGCAGGAATC CTCTATCTGG TCACACCTCC CAGTGTGGTG
    GGAGGCCTGG GAGTCACCAT GGTTCATGGA AATCTTACCG CTGGTCATGG TCTCCTGGTT
    GAGTTGATAA TCACATTTCA ATTGGTGTTT ACTATCTTTG CCAGCTGTGA TTCCAAACGG
    ACTGATGTCA CTGGCTCAAT AGCTTTAGCA ATTGGATTTT CTGTTGCAAT TGGACATTTA
    TTTGCAATCA ATTATACTGG TGCCAGCATG AATCCCGCCC GATCCTTTGG ACCTGCAGTT
    ATCATGGGAA ATTGGGAAAA CCATTGGATA TATTGGGTTG GGCCCATCAT AGGAGCTGTC
    CTCGCTGGTG GCCTTTATGA GTATGTCTTC TGTCCAGATG TTGAATTCAA ACGTCGTTTT
    AAAGAAGCCT TCAGCAAAGC TGCCCAGCAA ACAAAAGGAA GCTACATGGA GGTGGAGGAC
    AACAGGAGTC AGGTAGAGAC GGATGACCTG ATTCTAAAAC CTGGAGTGGT GCATGTGATT
    GACGTTGACC GGGGAGAGGA GAAGAAGGGG AAAGACCAAT CTGGAGAGGT ATTGTCTTCA
    GTATGACTAG AAGATCGCAC TGAAAGCAGA CAAGACTCCT TAGAACTGTC CTCAGATTTC
    CTTCCACCCA TTAAGGAAAC AGATTTGTTA TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu106841
    Clone ID Related Accession (Same CDS sequence) NM_001364287.1 , NM_001364289.1
    Accession Version NM_001364289.1 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 993bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-08-20
    Organism Homo sapiens(human)
    Product aquaporin-4 isoform M23x
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC018371.10, U34845.1, HQ901095.1, BC030745.1 and BU687682.1. Transcript Variant: This variant (2, also known as hMIWC1) is alternatively spliced at the 5' end, which causes translation initiation from an in-frame, downstream start codon, compared to variant 1. Variant 2 encodes two isoforms, resulting from the use of alternative in-frame translation termination codons. The encoded isoform (M23x, also known as M23ex), which results from readthrough of the upstream UGA stop codon to the downstream UAA stop codon, has a shorter N-terminus and a longer C-terminus compared to isoform M1. As the UGA stop codon has been reported to specify several alternative amino acids (tryptophan, cysteine, arginine and serine), its location in isoform M23x is denoted by an 'X'. This isoform is the same as that represented in NM_001364287.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.223531.1, SRR1660805.39318.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## stop codon readthrough :: PMID: 28206694 ##RefSeq-Attributes-END## COMPLETENESS: full length.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGGTGGCTT TCAAAGGGGT CTGGACTCAA GCTTTCTGGA AAGCAGTCAC AGCGGAATTT 
    CTGGCCATGC TTATTTTTGT TCTCCTCAGC CTGGGATCCA CCATCAACTG GGGTGGAACA
    GAAAAGCCTT TACCGGTCGA CATGGTTCTC ATCTCCCTTT GCTTTGGACT CAGCATTGCA
    ACCATGGTGC AGTGCTTTGG CCATATCAGC GGTGGCCACA TCAACCCTGC AGTGACTGTG
    GCCATGGTGT GCACCAGGAA GATCAGCATC GCCAAGTCTG TCTTCTACAT CGCAGCCCAG
    TGCCTGGGGG CCATCATTGG AGCAGGAATC CTCTATCTGG TCACACCTCC CAGTGTGGTG
    GGAGGCCTGG GAGTCACCAT GGTTCATGGA AATCTTACCG CTGGTCATGG TCTCCTGGTT
    GAGTTGATAA TCACATTTCA ATTGGTGTTT ACTATCTTTG CCAGCTGTGA TTCCAAACGG
    ACTGATGTCA CTGGCTCAAT AGCTTTAGCA ATTGGATTTT CTGTTGCAAT TGGACATTTA
    TTTGCAATCA ATTATACTGG TGCCAGCATG AATCCCGCCC GATCCTTTGG ACCTGCAGTT
    ATCATGGGAA ATTGGGAAAA CCATTGGATA TATTGGGTTG GGCCCATCAT AGGAGCTGTC
    CTCGCTGGTG GCCTTTATGA GTATGTCTTC TGTCCAGATG TTGAATTCAA ACGTCGTTTT
    AAAGAAGCCT TCAGCAAAGC TGCCCAGCAA ACAAAAGGAA GCTACATGGA GGTGGAGGAC
    AACAGGAGTC AGGTAGAGAC GGATGACCTG ATTCTAAAAC CTGGAGTGGT GCATGTGATT
    GACGTTGACC GGGGAGAGGA GAAGAAGGGG AAAGACCAAT CTGGAGAGGT ATTGTCTTCA
    GTATGACTAG AAGATCGCAC TGAAAGCAGA CAAGACTCCT TAGAACTGTC CTCAGATTTC
    CTTCCACCCA TTAAGGAAAC AGATTTGTTA TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001351218.1
    CDS349..1341
    Translation

    Target ORF information:

    RefSeq Version NM_001364289.1
    Organism Homo sapiens(human)
    Definition Homo sapiens aquaporin 4 (AQP4), transcript variant 2, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001364289.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGGTGGCTT TCAAAGGGGT CTGGACTCAA GCTTTCTGGA AAGCAGTCAC AGCGGAATTT 
    CTGGCCATGC TTATTTTTGT TCTCCTCAGC CTGGGATCCA CCATCAACTG GGGTGGAACA
    GAAAAGCCTT TACCGGTCGA CATGGTTCTC ATCTCCCTTT GCTTTGGACT CAGCATTGCA
    ACCATGGTGC AGTGCTTTGG CCATATCAGC GGTGGCCACA TCAACCCTGC AGTGACTGTG
    GCCATGGTGT GCACCAGGAA GATCAGCATC GCCAAGTCTG TCTTCTACAT CGCAGCCCAG
    TGCCTGGGGG CCATCATTGG AGCAGGAATC CTCTATCTGG TCACACCTCC CAGTGTGGTG
    GGAGGCCTGG GAGTCACCAT GGTTCATGGA AATCTTACCG CTGGTCATGG TCTCCTGGTT
    GAGTTGATAA TCACATTTCA ATTGGTGTTT ACTATCTTTG CCAGCTGTGA TTCCAAACGG
    ACTGATGTCA CTGGCTCAAT AGCTTTAGCA ATTGGATTTT CTGTTGCAAT TGGACATTTA
    TTTGCAATCA ATTATACTGG TGCCAGCATG AATCCCGCCC GATCCTTTGG ACCTGCAGTT
    ATCATGGGAA ATTGGGAAAA CCATTGGATA TATTGGGTTG GGCCCATCAT AGGAGCTGTC
    CTCGCTGGTG GCCTTTATGA GTATGTCTTC TGTCCAGATG TTGAATTCAA ACGTCGTTTT
    AAAGAAGCCT TCAGCAAAGC TGCCCAGCAA ACAAAAGGAA GCTACATGGA GGTGGAGGAC
    AACAGGAGTC AGGTAGAGAC GGATGACCTG ATTCTAAAAC CTGGAGTGGT GCATGTGATT
    GACGTTGACC GGGGAGAGGA GAAGAAGGGG AAAGACCAAT CTGGAGAGGT ATTGTCTTCA
    GTATGACTAG AAGATCGCAC TGAAAGCAGA CAAGACTCCT TAGAACTGTC CTCAGATTTC
    CTTCCACCCA TTAAGGAAAC AGATTTGTTA TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.