Gene Symbol | SP110 |
Entrez Gene ID | 3431 |
Full Name | SP110 nuclear body protein |
Synonyms | IFI41,IFI75,IPR1,VODI |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified. [provided by RefSeq, Jul 2008]. |
Disorder MIM: | |
Disorder Html: | Hepatic venoocclusive disease with immunodeficiency, 235550 (3); {Mycobacterium tuberculosis, susceptibility to}, 607948 (3) |