IDH3B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	IDH3B
Entrez Gene ID	3420
Full Name	isocitrate dehydrogenase 3 (NAD(+)) beta
Synonyms	RP46
General protein information	Preferred Names isocitrate dehydrogenase 3 (NAD(+)) beta Names isocitrate dehydrogenase [NAD] subunit beta, mitochondrial NAD(+)-specific ICDH subunit beta isocitrate dehydrogenase 3 (NAD+) beta isocitric dehydrogenase subunit beta
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 20 Map Location: 20p13
Summary	Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Sep 2016].
Disorder MIM:	604526
Disorder Html:	Retinitis pigmentosa 46, 612572 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_006899.5	NP_008830.2	isocitrate dehydrogenase [NAD] subunit beta, mitochondrial isoform a precursor
NM_001330763.1	NP_001317692.1	isocitrate dehydrogenase [NAD] subunit beta, mitochondrial isoform e precursor
NM_006899.3	NP_008830.2	isocitrate dehydrogenase [NAD] subunit beta, mitochondrial isoform a precursor
NM_001330763.2	NP_001317692.1	isocitrate dehydrogenase [NAD] subunit beta, mitochondrial isoform e precursor
NM_006899.4	NP_008830.2	isocitrate dehydrogenase [NAD] subunit beta, mitochondrial isoform a precursor
NM_174855.4	NP_777280.1	isocitrate dehydrogenase [NAD] subunit beta, mitochondrial isoform b precursor
NM_001258384.2	NP_001245313.1	isocitrate dehydrogenase [NAD] subunit beta, mitochondrial isoform d precursor
NM_174855.3	NP_777280.1	isocitrate dehydrogenase [NAD] subunit beta, mitochondrial isoform b precursor

Pathways from BioSystems

Homologies

Kluyveromyces lactis	KLLA0F04103g	XP_455266.1
Arabidopsis thaliana (thale cress)	IDH1	NP_195252.1
Canis lupus familiaris (dog)	IDH3B	XP_005634928.1
Drosophila melanogaster (fruit fly)	CG6439	NP_001163682.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007786	XP_317729.4
Saccharomyces cerevisiae (baker's yeast)	IDH1	NP_014361.1
Eremothecium gossypii	AGOS_ADL223W	NP_983873.1
Oryza sativa (rice)	Os02g0595500	NP_001047314.1
Xenopus tropicalis (tropical clawed frog)	idh3b	NP_001119993.1
Rattus norvegicus (Norway rat)	Idh3B	NP_446033.1
Danio rerio (zebrafish)	idh3b	NP_001002157.1
Caenorhabditis elegans (roundworm)	idhb-1	NP_510362.1
Schizosaccharomyces pombe (fission yeast)	idh1	NP_594397.1
Magnaporthe oryzae (rice blast fungus)	MGG_01995	XP_003708736.1
Neurospora crassa	NCU00775	XP_964931.2
Bos taurus (cattle)	IDH3B	NP_001139344.1
Oryza sativa (rice)	Os04g0479200	NP_001053093.1
Homo sapiens (human)	IDH3B	NP_008830.2
Pan troglodytes (chimpanzee)	IDH3B	XP_001157460.1
	IDH3B	XP_001114288.1
Mus musculus (house mouse)	Idh3b	NP_570954.1
Gallus gallus (chicken)	IDH3B	NP_001026558.1
Arabidopsis thaliana (thale cress)	IDH2	NP_179304.1

Gene Ontology
Bibliography

Related articles in PubMed

Proteomic characterization of the human sperm nucleus.
de Mateo S, Castillo J, Estanyol JM, Ballesc? JL, Oliva R
Proteomics11(13)2714-26(2011 Jul)

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ
PloS one5(9)e12862(2010 Sep)

Each conserved active site tyr in the three subunits of human isocitrate dehydrogenase has a different function.
Dange M, Colman RF
The Journal of biological chemistry285(27)20520-5(2010 Jul)

Neuro-oncology: Isocitrate dehydrogenase mutations in low-grade gliomas.
Schiff D, Purow BW
Nature reviews. Neurology5(6)303-4(2009 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association. (HuGE Navigator)
Title: Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

Human NAD-dependent isocitrate dehydrogenase (IDH) is a heterotetrameric mitochondrial enzyme with 2alpha:1beta:1gamma subunit ratio subunits shich share 40-52% identity in amino acid sequence.
Title: Each conserved active site tyr in the three subunits of human isocitrate dehydrogenase has a different function.

The point mutations of isocitrate dehydrogenase are essentially unique to gliomas.
Title: Neuro-oncology: Isocitrate dehydrogenase mutations in low-grade gliomas.

Homozygous for loss-of-function mutations in IDH3B is associated with retinitis pigmentosa.
Title: Insights from retinitis pigmentosa into the roles of isocitrate dehydrogenases in the Krebs cycle.

Asp192 is needed for optimal affinity of IDH beta subunit for nicotinamide-adenine dinucleotide (NAD) substrate, but is not critical for catalysis.
Title: Role of alpha-Asp181, beta-Asp192, and gamma-Asp190 in the distinctive subunits of human NAD-specific isocitrate dehydrogenase.

The following IDH3B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IDH3B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu19933	NM_006899.5 Latest version!	Homo sapiens isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta (IDH3B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu16892	NM_174855.4 Latest version!	Homo sapiens isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta (IDH3B), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu20846	NM_001258384.2 Latest version!	Homo sapiens isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta (IDH3B), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu52711	NM_001330763.2 Latest version!	Homo sapiens isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta (IDH3B), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
View Old Accession Versions >>
OHu19933	NM_006899.3	Homo sapiens isocitrate dehydrogenase 3 (NAD+) beta (IDH3B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu52711	NM_001330763.1	Homo sapiens isocitrate dehydrogenase 3 (NAD(+)) beta (IDH3B), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu19933	NM_006899.4	Homo sapiens isocitrate dehydrogenase 3 (NAD(+)) beta (IDH3B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu16892	NM_174855.3	Homo sapiens isocitrate dehydrogenase 3 (NAD(+)) beta (IDH3B), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IDH3B ( NM_006899.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_008830.2 Homo sapiens isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta (IDH3B), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu19933
Clone ID Related Accession (Same CDS sequence)	NM_006899.5 , NM_006899.3 , NM_006899.4
Accession Version	NM_006899.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1158bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	isocitrate dehydrogenase [NAD] subunit beta, mitochondrial isoform a precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY131986.1 and BC001960.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_006899.4. Transcript Variant: This variant (1) represents the predominate transcript and encodes isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189652.130447.1, SRR3476690.285142.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta MANE Ensembl match :: ENST00000380843.9/ ENSP00000370223.4 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGCAT TGAGCGGAGT CCGCTGGCTG ACCCGAGCGC TGGTCTCCGC CGGGAACCCT 
GGGGCATGGA GAGGTCTGAG TACCTCGGCC GCGGCGCACG CTGCATCGCG GAGCCAGGCC 
GAGGACGTGA GGGTGGAGGG CTCCTTTCCC GTGACCATGC TTCCGGGAGA CGGTGTGGGG 
CCTGAGCTGA TGCACGCCGT CAAGGAGGTG TTCAAGGCTG CCGCTGTCCC AGTGGAGTTC 
CAGGAGCACC ACCTGAGTGA GGTGCAGAAT ATGGCATCTG AGGAGAAGCT GGAGCAGGTG 
CTGAGTTCCA TGAAGGAGAA CAAAGTGGCC ATCATTGGAA AGATTCATAC CCCGATGGAG 
TATAAGGGGG AGCTAGCCTC CTATGATATG CGGCTGAGGC GTAAGTTGGA CTTATTTGCC 
AACGTAGTCC ATGTGAAGTC ACTTCCTGGG TATATGACTC GGCACAACAA TCTAGACCTG 
GTGATCATTC GAGAGCAGAC AGAAGGGGAG TACAGCTCTC TGGAACATGA GAGTGCAAGG 
GGTGTGATTG AGTGTTTGAA GATTGTCACA CGAGCCAAGT CTCAGCGGAT TGCAAAGTTC 
GCCTTTGACT ATGCCACCAA GAAGGGGCGG GGCAAGGTCA CTGCTGTCCA CAAGGCCAAC 
ATCATGAAAC TTGGGGATGG GTTGTTCCTG CAGTGCTGTG AGGAAGTTGC TGAACTGTAC 
CCCAAAATCA AATTTGAGAC AATGATCATA GACAACTGCT GCATGCAGCT GGTGCAGAAT 
CCTTACCAGT TTGATGTGCT TGTGATGCCC AATCTCTATG GGAACATTAT TGACAATCTG 
GCTGCTGGCC TGGTTGGGGG AGCTGGTGTG GTCCCTGGTG AGAGCTATAG TGCAGAATAC 
GCAGTCTTTG AGACGGGTGC CCGGCACCCA TTTGCCCAGG CAGTGGGCAG GAATATAGCC 
AATCCCACGG CCATGCTGCT GTCGGCTTCC AACATGCTGC GGCATCTTAA TCTTGAGTAT 
CACTCCAGCA TGATCGCAGA TGCGGTGAAG AAGGTGATCA AAGTTGGCAA GGTGCGGACT 
CGAGACATGG GCGGCTACAG CACCACAACC GACTTCATCA AGTCTGTCAT CGGTCACCTG 
CAGACTAAAG GGAGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_008830.2
CDS	29..1186
Translation	MAALSGVRWLTRALVSAGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVGPELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFIKSVIGHLQTKGS

Target ORF information:

RefSeq Version	NM_006899.5
Organism	Homo sapiens(human)
Definition	Homo sapiens isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta (IDH3B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006899.5

ORF Insert Sequence:

ATGGCGGCAT TGAGCGGAGT CCGCTGGCTG ACCCGAGCGC TGGTCTCCGC CGGGAACCCT 
GGGGCATGGA GAGGTCTGAG TACCTCGGCC GCGGCGCACG CTGCATCGCG GAGCCAGGCC 
GAGGACGTGA GGGTGGAGGG CTCCTTTCCC GTGACCATGC TTCCGGGAGA CGGTGTGGGG 
CCTGAGCTGA TGCACGCCGT CAAGGAGGTG TTCAAGGCTG CCGCTGTCCC AGTGGAGTTC 
CAGGAGCACC ACCTGAGTGA GGTGCAGAAT ATGGCATCTG AGGAGAAGCT GGAGCAGGTG 
CTGAGTTCCA TGAAGGAGAA CAAAGTGGCC ATCATTGGAA AGATTCATAC CCCGATGGAG 
TATAAGGGGG AGCTAGCCTC CTATGATATG CGGCTGAGGC GTAAGTTGGA CTTATTTGCC 
AACGTAGTCC ATGTGAAGTC ACTTCCTGGG TATATGACTC GGCACAACAA TCTAGACCTG 
GTGATCATTC GAGAGCAGAC AGAAGGGGAG TACAGCTCTC TGGAACATGA GAGTGCAAGG 
GGTGTGATTG AGTGTTTGAA GATTGTCACA CGAGCCAAGT CTCAGCGGAT TGCAAAGTTC 
GCCTTTGACT ATGCCACCAA GAAGGGGCGG GGCAAGGTCA CTGCTGTCCA CAAGGCCAAC 
ATCATGAAAC TTGGGGATGG GTTGTTCCTG CAGTGCTGTG AGGAAGTTGC TGAACTGTAC 
CCCAAAATCA AATTTGAGAC AATGATCATA GACAACTGCT GCATGCAGCT GGTGCAGAAT 
CCTTACCAGT TTGATGTGCT TGTGATGCCC AATCTCTATG GGAACATTAT TGACAATCTG 
GCTGCTGGCC TGGTTGGGGG AGCTGGTGTG GTCCCTGGTG AGAGCTATAG TGCAGAATAC 
GCAGTCTTTG AGACGGGTGC CCGGCACCCA TTTGCCCAGG CAGTGGGCAG GAATATAGCC 
AATCCCACGG CCATGCTGCT GTCGGCTTCC AACATGCTGC GGCATCTTAA TCTTGAGTAT 
CACTCCAGCA TGATCGCAGA TGCGGTGAAG AAGGTGATCA AAGTTGGCAA GGTGCGGACT 
CGAGACATGG GCGGCTACAG CACCACAACC GACTTCATCA AGTCTGTCAT CGGTCACCTG 
CAGACTAAAG GGAGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IDH3B ( NM_006899.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_008830.2 Homo sapiens isocitrate dehydrogenase 3 (NAD+) beta (IDH3B), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu19933
Clone ID Related Accession (Same CDS sequence)	NM_006899.5 , NM_006899.3 , NM_006899.4
Accession Version	NM_006899.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1158bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	isocitrate dehydrogenase [NAD] subunit beta, mitochondrial isoform a precursor
Comment

ATGGCGGCAT TGAGCGGAGT CCGCTGGCTG ACCCGAGCGC TGGTCTCCGC CGGGAACCCT 
GGGGCATGGA GAGGTCTGAG TACCTCGGCC GCGGCGCACG CTGCATCGCG GAGCCAGGCC 
GAGGACGTGA GGGTGGAGGG CTCCTTTCCC GTGACCATGC TTCCGGGAGA CGGTGTGGGG 
CCTGAGCTGA TGCACGCCGT CAAGGAGGTG TTCAAGGCTG CCGCTGTCCC AGTGGAGTTC 
CAGGAGCACC ACCTGAGTGA GGTGCAGAAT ATGGCATCTG AGGAGAAGCT GGAGCAGGTG 
CTGAGTTCCA TGAAGGAGAA CAAAGTGGCC ATCATTGGAA AGATTCATAC CCCGATGGAG 
TATAAGGGGG AGCTAGCCTC CTATGATATG CGGCTGAGGC GTAAGTTGGA CTTATTTGCC 
AACGTAGTCC ATGTGAAGTC ACTTCCTGGG TATATGACTC GGCACAACAA TCTAGACCTG 
GTGATCATTC GAGAGCAGAC AGAAGGGGAG TACAGCTCTC TGGAACATGA GAGTGCAAGG 
GGTGTGATTG AGTGTTTGAA GATTGTCACA CGAGCCAAGT CTCAGCGGAT TGCAAAGTTC 
GCCTTTGACT ATGCCACCAA GAAGGGGCGG GGCAAGGTCA CTGCTGTCCA CAAGGCCAAC 
ATCATGAAAC TTGGGGATGG GTTGTTCCTG CAGTGCTGTG AGGAAGTTGC TGAACTGTAC 
CCCAAAATCA AATTTGAGAC AATGATCATA GACAACTGCT GCATGCAGCT GGTGCAGAAT 
CCTTACCAGT TTGATGTGCT TGTGATGCCC AATCTCTATG GGAACATTAT TGACAATCTG 
GCTGCTGGCC TGGTTGGGGG AGCTGGTGTG GTCCCTGGTG AGAGCTATAG TGCAGAATAC 
GCAGTCTTTG AGACGGGTGC CCGGCACCCA TTTGCCCAGG CAGTGGGCAG GAATATAGCC 
AATCCCACGG CCATGCTGCT GTCGGCTTCC AACATGCTGC GGCATCTTAA TCTTGAGTAT 
CACTCCAGCA TGATCGCAGA TGCGGTGAAG AAGGTGATCA AAGTTGGCAA GGTGCGGACT 
CGAGACATGG GCGGCTACAG CACCACAACC GACTTCATCA AGTCTGTCAT CGGTCACCTG 
CAGACTAAAG GGAGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_008830.2
Translation	MAALSGVRWLTRALVSAGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVGPELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFIKSVIGHLQTKGS

Target ORF information:

RefSeq Version	NM_006899.3
Organism	Homo sapiens(Human)
Definition	Homo sapiens isocitrate dehydrogenase 3 (NAD+) beta (IDH3B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006899.3

ORF Insert Sequence:

ATGGCGGCAT TGAGCGGAGT CCGCTGGCTG ACCCGAGCGC TGGTCTCCGC CGGGAACCCT 
GGGGCATGGA GAGGTCTGAG TACCTCGGCC GCGGCGCACG CTGCATCGCG GAGCCAGGCC 
GAGGACGTGA GGGTGGAGGG CTCCTTTCCC GTGACCATGC TTCCGGGAGA CGGTGTGGGG 
CCTGAGCTGA TGCACGCCGT CAAGGAGGTG TTCAAGGCTG CCGCTGTCCC AGTGGAGTTC 
CAGGAGCACC ACCTGAGTGA GGTGCAGAAT ATGGCATCTG AGGAGAAGCT GGAGCAGGTG 
CTGAGTTCCA TGAAGGAGAA CAAAGTGGCC ATCATTGGAA AGATTCATAC CCCGATGGAG 
TATAAGGGGG AGCTAGCCTC CTATGATATG CGGCTGAGGC GTAAGTTGGA CTTATTTGCC 
AACGTAGTCC ATGTGAAGTC ACTTCCTGGG TATATGACTC GGCACAACAA TCTAGACCTG 
GTGATCATTC GAGAGCAGAC AGAAGGGGAG TACAGCTCTC TGGAACATGA GAGTGCAAGG 
GGTGTGATTG AGTGTTTGAA GATTGTCACA CGAGCCAAGT CTCAGCGGAT TGCAAAGTTC 
GCCTTTGACT ATGCCACCAA GAAGGGGCGG GGCAAGGTCA CTGCTGTCCA CAAGGCCAAC 
ATCATGAAAC TTGGGGATGG GTTGTTCCTG CAGTGCTGTG AGGAAGTTGC TGAACTGTAC 
CCCAAAATCA AATTTGAGAC AATGATCATA GACAACTGCT GCATGCAGCT GGTGCAGAAT 
CCTTACCAGT TTGATGTGCT TGTGATGCCC AATCTCTATG GGAACATTAT TGACAATCTG 
GCTGCTGGCC TGGTTGGGGG AGCTGGTGTG GTCCCTGGTG AGAGCTATAG TGCAGAATAC 
GCAGTCTTTG AGACGGGTGC CCGGCACCCA TTTGCCCAGG CAGTGGGCAG GAATATAGCC 
AATCCCACGG CCATGCTGCT GTCGGCTTCC AACATGCTGC GGCATCTTAA TCTTGAGTAT 
CACTCCAGCA TGATCGCAGA TGCGGTGAAG AAGGTGATCA AAGTTGGCAA GGTGCGGACT 
CGAGACATGG GCGGCTACAG CACCACAACC GACTTCATCA AGTCTGTCAT CGGTCACCTG 
CAGACTAAAG GGAGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IDH3B ( NM_006899.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_008830.2 Homo sapiens isocitrate dehydrogenase 3 (NAD(+)) beta (IDH3B), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu19933
Clone ID Related Accession (Same CDS sequence)	NM_006899.5 , NM_006899.3 , NM_006899.4
Accession Version	NM_006899.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1158bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-26
Organism	Homo sapiens(human)
Product	isocitrate dehydrogenase [NAD] subunit beta, mitochondrial isoform a precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY131986.1, BC001960.1 and BX119223.1. This sequence is a reference standard in the RefSeqGene project. On Apr 13, 2016 this sequence version replaced NM_006899.3. Transcript Variant: This variant (1) represents the predominate transcript and encodes isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BX647393.1, SRR1163655.49792.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCAT TGAGCGGAGT CCGCTGGCTG ACCCGAGCGC TGGTCTCCGC CGGGAACCCT 
GGGGCATGGA GAGGTCTGAG TACCTCGGCC GCGGCGCACG CTGCATCGCG GAGCCAGGCC 
GAGGACGTGA GGGTGGAGGG CTCCTTTCCC GTGACCATGC TTCCGGGAGA CGGTGTGGGG 
CCTGAGCTGA TGCACGCCGT CAAGGAGGTG TTCAAGGCTG CCGCTGTCCC AGTGGAGTTC 
CAGGAGCACC ACCTGAGTGA GGTGCAGAAT ATGGCATCTG AGGAGAAGCT GGAGCAGGTG 
CTGAGTTCCA TGAAGGAGAA CAAAGTGGCC ATCATTGGAA AGATTCATAC CCCGATGGAG 
TATAAGGGGG AGCTAGCCTC CTATGATATG CGGCTGAGGC GTAAGTTGGA CTTATTTGCC 
AACGTAGTCC ATGTGAAGTC ACTTCCTGGG TATATGACTC GGCACAACAA TCTAGACCTG 
GTGATCATTC GAGAGCAGAC AGAAGGGGAG TACAGCTCTC TGGAACATGA GAGTGCAAGG 
GGTGTGATTG AGTGTTTGAA GATTGTCACA CGAGCCAAGT CTCAGCGGAT TGCAAAGTTC 
GCCTTTGACT ATGCCACCAA GAAGGGGCGG GGCAAGGTCA CTGCTGTCCA CAAGGCCAAC 
ATCATGAAAC TTGGGGATGG GTTGTTCCTG CAGTGCTGTG AGGAAGTTGC TGAACTGTAC 
CCCAAAATCA AATTTGAGAC AATGATCATA GACAACTGCT GCATGCAGCT GGTGCAGAAT 
CCTTACCAGT TTGATGTGCT TGTGATGCCC AATCTCTATG GGAACATTAT TGACAATCTG 
GCTGCTGGCC TGGTTGGGGG AGCTGGTGTG GTCCCTGGTG AGAGCTATAG TGCAGAATAC 
GCAGTCTTTG AGACGGGTGC CCGGCACCCA TTTGCCCAGG CAGTGGGCAG GAATATAGCC 
AATCCCACGG CCATGCTGCT GTCGGCTTCC AACATGCTGC GGCATCTTAA TCTTGAGTAT 
CACTCCAGCA TGATCGCAGA TGCGGTGAAG AAGGTGATCA AAGTTGGCAA GGTGCGGACT 
CGAGACATGG GCGGCTACAG CACCACAACC GACTTCATCA AGTCTGTCAT CGGTCACCTG 
CAGACTAAAG GGAGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_008830.2
CDS	36..1193
Translation	MAALSGVRWLTRALVSAGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVGPELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFIKSVIGHLQTKGS

Target ORF information:

RefSeq Version	NM_006899.4
Organism	Homo sapiens(human)
Definition	Homo sapiens isocitrate dehydrogenase 3 (NAD(+)) beta (IDH3B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006899.4

ORF Insert Sequence:

ATGGCGGCAT TGAGCGGAGT CCGCTGGCTG ACCCGAGCGC TGGTCTCCGC CGGGAACCCT 
GGGGCATGGA GAGGTCTGAG TACCTCGGCC GCGGCGCACG CTGCATCGCG GAGCCAGGCC 
GAGGACGTGA GGGTGGAGGG CTCCTTTCCC GTGACCATGC TTCCGGGAGA CGGTGTGGGG 
CCTGAGCTGA TGCACGCCGT CAAGGAGGTG TTCAAGGCTG CCGCTGTCCC AGTGGAGTTC 
CAGGAGCACC ACCTGAGTGA GGTGCAGAAT ATGGCATCTG AGGAGAAGCT GGAGCAGGTG 
CTGAGTTCCA TGAAGGAGAA CAAAGTGGCC ATCATTGGAA AGATTCATAC CCCGATGGAG 
TATAAGGGGG AGCTAGCCTC CTATGATATG CGGCTGAGGC GTAAGTTGGA CTTATTTGCC 
AACGTAGTCC ATGTGAAGTC ACTTCCTGGG TATATGACTC GGCACAACAA TCTAGACCTG 
GTGATCATTC GAGAGCAGAC AGAAGGGGAG TACAGCTCTC TGGAACATGA GAGTGCAAGG 
GGTGTGATTG AGTGTTTGAA GATTGTCACA CGAGCCAAGT CTCAGCGGAT TGCAAAGTTC 
GCCTTTGACT ATGCCACCAA GAAGGGGCGG GGCAAGGTCA CTGCTGTCCA CAAGGCCAAC 
ATCATGAAAC TTGGGGATGG GTTGTTCCTG CAGTGCTGTG AGGAAGTTGC TGAACTGTAC 
CCCAAAATCA AATTTGAGAC AATGATCATA GACAACTGCT GCATGCAGCT GGTGCAGAAT 
CCTTACCAGT TTGATGTGCT TGTGATGCCC AATCTCTATG GGAACATTAT TGACAATCTG 
GCTGCTGGCC TGGTTGGGGG AGCTGGTGTG GTCCCTGGTG AGAGCTATAG TGCAGAATAC 
GCAGTCTTTG AGACGGGTGC CCGGCACCCA TTTGCCCAGG CAGTGGGCAG GAATATAGCC 
AATCCCACGG CCATGCTGCT GTCGGCTTCC AACATGCTGC GGCATCTTAA TCTTGAGTAT 
CACTCCAGCA TGATCGCAGA TGCGGTGAAG AAGGTGATCA AAGTTGGCAA GGTGCGGACT 
CGAGACATGG GCGGCTACAG CACCACAACC GACTTCATCA AGTCTGTCAT CGGTCACCTG 
CAGACTAAAG GGAGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IDH3B ( NM_174855.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_777280.1 Homo sapiens isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta (IDH3B), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu16892
Clone ID Related Accession (Same CDS sequence)	NM_174855.4 , NM_174855.3
Accession Version	NM_174855.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1152bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Homo sapiens(human)
Product	isocitrate dehydrogenase [NAD] subunit beta, mitochondrial isoform b precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY131986.1, BC001960.1 and BG745042.1. On May 31, 2019 this sequence version replaced NM_174855.3. Transcript Variant: This variant (2) lacks a portion of the coding region which results in a frameshift and an early stop codon, compared to variant 1. The encoded isoform (b) is shorter and has a distinct C-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189655.62584.1, SRR5189655.193479.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCAT TGAGCGGAGT CCGCTGGCTG ACCCGAGCGC TGGTCTCCGC CGGGAACCCT 
GGGGCATGGA GAGGTCTGAG TACCTCGGCC GCGGCGCACG CTGCATCGCG GAGCCAGGCC 
GAGGACGTGA GGGTGGAGGG CTCCTTTCCC GTGACCATGC TTCCGGGAGA CGGTGTGGGG 
CCTGAGCTGA TGCACGCCGT CAAGGAGGTG TTCAAGGCTG CCGCTGTCCC AGTGGAGTTC 
CAGGAGCACC ACCTGAGTGA GGTGCAGAAT ATGGCATCTG AGGAGAAGCT GGAGCAGGTG 
CTGAGTTCCA TGAAGGAGAA CAAAGTGGCC ATCATTGGAA AGATTCATAC CCCGATGGAG 
TATAAGGGGG AGCTAGCCTC CTATGATATG CGGCTGAGGC GTAAGTTGGA CTTATTTGCC 
AACGTAGTCC ATGTGAAGTC ACTTCCTGGG TATATGACTC GGCACAACAA TCTAGACCTG 
GTGATCATTC GAGAGCAGAC AGAAGGGGAG TACAGCTCTC TGGAACATGA GAGTGCAAGG 
GGTGTGATTG AGTGTTTGAA GATTGTCACA CGAGCCAAGT CTCAGCGGAT TGCAAAGTTC 
GCCTTTGACT ATGCCACCAA GAAGGGGCGG GGCAAGGTCA CTGCTGTCCA CAAGGCCAAC 
ATCATGAAAC TTGGGGATGG GTTGTTCCTG CAGTGCTGTG AGGAAGTTGC TGAACTGTAC 
CCCAAAATCA AATTTGAGAC AATGATCATA GACAACTGCT GCATGCAGCT GGTGCAGAAT 
CCTTACCAGT TTGATGTGCT TGTGATGCCC AATCTCTATG GGAACATTAT TGACAATCTG 
GCTGCTGGCC TGGTTGGGGG AGCTGGTGTG GTCCCTGGTG AGAGCTATAG TGCAGAATAC 
GCAGTCTTTG AGACGGGTGC CCGGCACCCA TTTGCCCAGG CAGTGGGCAG GAATATAGCC 
AATCCCACGG CCATGCTGCT GTCGGCTTCC AACATGCTGC GGCATCTTAA TCTTGAGTAT 
CACTCCAGCA TGATCGCAGA TGCGGTGAAG AAGGTGATCA AAGTTGGCAA GGTTCGAACC 
TCTGACATGG GTGGCTATGC TACTTGCCAT GACTTCACTG AGGCTGTCAT TGCTGCCTTG 
CCCCACCCAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_777280.1
CDS	29..1180
Translation	MAALSGVRWLTRALVSAGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVGPELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTSDMGGYATCHDFTEAVIAALPHP

Target ORF information:

RefSeq Version	NM_174855.4
Organism	Homo sapiens(human)
Definition	Homo sapiens isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta (IDH3B), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174855.4

ORF Insert Sequence:

ATGGCGGCAT TGAGCGGAGT CCGCTGGCTG ACCCGAGCGC TGGTCTCCGC CGGGAACCCT 
GGGGCATGGA GAGGTCTGAG TACCTCGGCC GCGGCGCACG CTGCATCGCG GAGCCAGGCC 
GAGGACGTGA GGGTGGAGGG CTCCTTTCCC GTGACCATGC TTCCGGGAGA CGGTGTGGGG 
CCTGAGCTGA TGCACGCCGT CAAGGAGGTG TTCAAGGCTG CCGCTGTCCC AGTGGAGTTC 
CAGGAGCACC ACCTGAGTGA GGTGCAGAAT ATGGCATCTG AGGAGAAGCT GGAGCAGGTG 
CTGAGTTCCA TGAAGGAGAA CAAAGTGGCC ATCATTGGAA AGATTCATAC CCCGATGGAG 
TATAAGGGGG AGCTAGCCTC CTATGATATG CGGCTGAGGC GTAAGTTGGA CTTATTTGCC 
AACGTAGTCC ATGTGAAGTC ACTTCCTGGG TATATGACTC GGCACAACAA TCTAGACCTG 
GTGATCATTC GAGAGCAGAC AGAAGGGGAG TACAGCTCTC TGGAACATGA GAGTGCAAGG 
GGTGTGATTG AGTGTTTGAA GATTGTCACA CGAGCCAAGT CTCAGCGGAT TGCAAAGTTC 
GCCTTTGACT ATGCCACCAA GAAGGGGCGG GGCAAGGTCA CTGCTGTCCA CAAGGCCAAC 
ATCATGAAAC TTGGGGATGG GTTGTTCCTG CAGTGCTGTG AGGAAGTTGC TGAACTGTAC 
CCCAAAATCA AATTTGAGAC AATGATCATA GACAACTGCT GCATGCAGCT GGTGCAGAAT 
CCTTACCAGT TTGATGTGCT TGTGATGCCC AATCTCTATG GGAACATTAT TGACAATCTG 
GCTGCTGGCC TGGTTGGGGG AGCTGGTGTG GTCCCTGGTG AGAGCTATAG TGCAGAATAC 
GCAGTCTTTG AGACGGGTGC CCGGCACCCA TTTGCCCAGG CAGTGGGCAG GAATATAGCC 
AATCCCACGG CCATGCTGCT GTCGGCTTCC AACATGCTGC GGCATCTTAA TCTTGAGTAT 
CACTCCAGCA TGATCGCAGA TGCGGTGAAG AAGGTGATCA AAGTTGGCAA GGTTCGAACC 
TCTGACATGG GTGGCTATGC TACTTGCCAT GACTTCACTG AGGCTGTCAT TGCTGCCTTG 
CCCCACCCAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IDH3B ( NM_174855.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_777280.1 Homo sapiens isocitrate dehydrogenase 3 (NAD(+)) beta (IDH3B), transcript variant 2, mRNA.

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CloneID	OHu16892
Clone ID Related Accession (Same CDS sequence)	NM_174855.4 , NM_174855.3
Accession Version	NM_174855.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1152bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-30
Organism	Homo sapiens(human)
Product	isocitrate dehydrogenase [NAD] subunit beta, mitochondrial isoform b precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY131986.1, BC001960.1, BG745042.1 and BX119223.1. On Apr 13, 2016 this sequence version replaced NM_174855.2. Transcript Variant: This variant (2) lacks a portion of the coding region which results in a frameshift and an early stop codon, compared to variant 1. The encoded isoform (b) is shorter and has a distinct C-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: ERR279837.5815.1, SRR1803615.427214.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCAT TGAGCGGAGT CCGCTGGCTG ACCCGAGCGC TGGTCTCCGC CGGGAACCCT 
GGGGCATGGA GAGGTCTGAG TACCTCGGCC GCGGCGCACG CTGCATCGCG GAGCCAGGCC 
GAGGACGTGA GGGTGGAGGG CTCCTTTCCC GTGACCATGC TTCCGGGAGA CGGTGTGGGG 
CCTGAGCTGA TGCACGCCGT CAAGGAGGTG TTCAAGGCTG CCGCTGTCCC AGTGGAGTTC 
CAGGAGCACC ACCTGAGTGA GGTGCAGAAT ATGGCATCTG AGGAGAAGCT GGAGCAGGTG 
CTGAGTTCCA TGAAGGAGAA CAAAGTGGCC ATCATTGGAA AGATTCATAC CCCGATGGAG 
TATAAGGGGG AGCTAGCCTC CTATGATATG CGGCTGAGGC GTAAGTTGGA CTTATTTGCC 
AACGTAGTCC ATGTGAAGTC ACTTCCTGGG TATATGACTC GGCACAACAA TCTAGACCTG 
GTGATCATTC GAGAGCAGAC AGAAGGGGAG TACAGCTCTC TGGAACATGA GAGTGCAAGG 
GGTGTGATTG AGTGTTTGAA GATTGTCACA CGAGCCAAGT CTCAGCGGAT TGCAAAGTTC 
GCCTTTGACT ATGCCACCAA GAAGGGGCGG GGCAAGGTCA CTGCTGTCCA CAAGGCCAAC 
ATCATGAAAC TTGGGGATGG GTTGTTCCTG CAGTGCTGTG AGGAAGTTGC TGAACTGTAC 
CCCAAAATCA AATTTGAGAC AATGATCATA GACAACTGCT GCATGCAGCT GGTGCAGAAT 
CCTTACCAGT TTGATGTGCT TGTGATGCCC AATCTCTATG GGAACATTAT TGACAATCTG 
GCTGCTGGCC TGGTTGGGGG AGCTGGTGTG GTCCCTGGTG AGAGCTATAG TGCAGAATAC 
GCAGTCTTTG AGACGGGTGC CCGGCACCCA TTTGCCCAGG CAGTGGGCAG GAATATAGCC 
AATCCCACGG CCATGCTGCT GTCGGCTTCC AACATGCTGC GGCATCTTAA TCTTGAGTAT 
CACTCCAGCA TGATCGCAGA TGCGGTGAAG AAGGTGATCA AAGTTGGCAA GGTTCGAACC 
TCTGACATGG GTGGCTATGC TACTTGCCAT GACTTCACTG AGGCTGTCAT TGCTGCCTTG 
CCCCACCCAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_777280.1
CDS	36..1187
Translation	MAALSGVRWLTRALVSAGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVGPELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTSDMGGYATCHDFTEAVIAALPHP

Target ORF information:

RefSeq Version	NM_174855.3
Organism	Homo sapiens(human)
Definition	Homo sapiens isocitrate dehydrogenase 3 (NAD(+)) beta (IDH3B), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174855.3

ORF Insert Sequence:

ATGGCGGCAT TGAGCGGAGT CCGCTGGCTG ACCCGAGCGC TGGTCTCCGC CGGGAACCCT 
GGGGCATGGA GAGGTCTGAG TACCTCGGCC GCGGCGCACG CTGCATCGCG GAGCCAGGCC 
GAGGACGTGA GGGTGGAGGG CTCCTTTCCC GTGACCATGC TTCCGGGAGA CGGTGTGGGG 
CCTGAGCTGA TGCACGCCGT CAAGGAGGTG TTCAAGGCTG CCGCTGTCCC AGTGGAGTTC 
CAGGAGCACC ACCTGAGTGA GGTGCAGAAT ATGGCATCTG AGGAGAAGCT GGAGCAGGTG 
CTGAGTTCCA TGAAGGAGAA CAAAGTGGCC ATCATTGGAA AGATTCATAC CCCGATGGAG 
TATAAGGGGG AGCTAGCCTC CTATGATATG CGGCTGAGGC GTAAGTTGGA CTTATTTGCC 
AACGTAGTCC ATGTGAAGTC ACTTCCTGGG TATATGACTC GGCACAACAA TCTAGACCTG 
GTGATCATTC GAGAGCAGAC AGAAGGGGAG TACAGCTCTC TGGAACATGA GAGTGCAAGG 
GGTGTGATTG AGTGTTTGAA GATTGTCACA CGAGCCAAGT CTCAGCGGAT TGCAAAGTTC 
GCCTTTGACT ATGCCACCAA GAAGGGGCGG GGCAAGGTCA CTGCTGTCCA CAAGGCCAAC 
ATCATGAAAC TTGGGGATGG GTTGTTCCTG CAGTGCTGTG AGGAAGTTGC TGAACTGTAC 
CCCAAAATCA AATTTGAGAC AATGATCATA GACAACTGCT GCATGCAGCT GGTGCAGAAT 
CCTTACCAGT TTGATGTGCT TGTGATGCCC AATCTCTATG GGAACATTAT TGACAATCTG 
GCTGCTGGCC TGGTTGGGGG AGCTGGTGTG GTCCCTGGTG AGAGCTATAG TGCAGAATAC 
GCAGTCTTTG AGACGGGTGC CCGGCACCCA TTTGCCCAGG CAGTGGGCAG GAATATAGCC 
AATCCCACGG CCATGCTGCT GTCGGCTTCC AACATGCTGC GGCATCTTAA TCTTGAGTAT 
CACTCCAGCA TGATCGCAGA TGCGGTGAAG AAGGTGATCA AAGTTGGCAA GGTTCGAACC 
TCTGACATGG GTGGCTATGC TACTTGCCAT GACTTCACTG AGGCTGTCAT TGCTGCCTTG 
CCCCACCCAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IDH3B ( NM_001258384.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001245313.1 Homo sapiens isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta (IDH3B), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu20846
Clone ID Related Accession (Same CDS sequence)	NM_001258384.2
Accession Version	NM_001258384.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1131bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Homo sapiens(human)
Product	isocitrate dehydrogenase [NAD] subunit beta, mitochondrial isoform d precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY131986.1, AK309488.1 and AL049712.12. On Apr 13, 2016 this sequence version replaced NM_001258384.1. Transcript Variant: This variant (4) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (d) has a shorter and distinct C-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.124915.1, SRR1660807.167247.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END##

ATGGCGGCAT TGAGCGGAGT CCGCTGGCTG ACCCGAGCGC TGGTCTCCGC CGGGAACCCT 
GGGGCATGGA GAGGTCTGAG TACCTCGGCC GCGGCGCACG CTGCATCGCG GAGCCAGGCC 
GAGGACGTGA GGGTGGAGGG CTCCTTTCCC GTGACCATGC TTCCGGGAGA CGGTGTGGGG 
CCTGAGCTGA TGCACGCCGT CAAGGAGGTG TTCAAGGCTG CCGCTGTCCC AGTGGAGTTC 
CAGGAGCACC ACCTGAGTGA GGTGCAGAAT ATGGCATCTG AGGAGAAGCT GGAGCAGGTG 
CTGAGTTCCA TGAAGGAGAA CAAAGTGGCC ATCATTGGAA AGATTCATAC CCCGATGGAG 
TATAAGGGGG AGCTAGCCTC CTATGATATG CGGCTGAGGC GTAAGTTGGA CTTATTTGCC 
AACGTAGTCC ATGTGAAGTC ACTTCCTGGG TATATGACTC GGCACAACAA TCTAGACCTG 
GTGATCATTC GAGAGCAGAC AGAAGGGGAG TACAGCTCTC TGGAACATGA GAGTGCAAGG 
GGTGTGATTG AGTGTTTGAA GATTGTCACA CGAGCCAAGT CTCAGCGGAT TGCAAAGTTC 
GCCTTTGACT ATGCCACCAA GAAGGGGCGG GGCAAGGTCA CTGCTGTCCA CAAGGCCAAC 
ATCATGAAAC TTGGGGATGG GTTGTTCCTG CAGTGCTGTG AGGAAGTTGC TGAACTGTAC 
CCCAAAATCA AATTTGAGAC AATGATCATA GACAACTGCT GCATGCAGCT GGTGCAGAAT 
CCTTACCAGT TTGATGTGCT TGTGATGCCC AATCTCTATG GGAACATTAT TGACAATCTG 
GCTGCTGGCC TGGTTGGGGG AGCTGGTGTG GTCCCTGGTG AGAGCTATAG TGCAGAATAC 
GCAGTCTTTG AGACGGGTGC CCGGCACCCA TTTGCCCAGG CAGTGGGCAG GAATATAGCC 
AATCCCACGG CCATGCTGCT GTCGGCTTCC AACATGCTGC GGCATCTTAA TCTTGAGTAT 
CACTCCAGCA TGATCGCAGA TGCGGTGAAG AAGGTGATCA AAGTTGGCAA GATCCCATCT 
GCTGTTCCCT CTTTCCTGCT CCATCCACTG CCCTTTTCAT GGGCCATCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001245313.1
CDS	36..1166
Translation	MAALSGVRWLTRALVSAGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVGPELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKIPSAVPSFLLHPLPFSWAI

Target ORF information:

RefSeq Version	NM_001258384.2
Organism	Homo sapiens(human)
Definition	Homo sapiens isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta (IDH3B), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001258384.2

ORF Insert Sequence:

ATGGCGGCAT TGAGCGGAGT CCGCTGGCTG ACCCGAGCGC TGGTCTCCGC CGGGAACCCT 
GGGGCATGGA GAGGTCTGAG TACCTCGGCC GCGGCGCACG CTGCATCGCG GAGCCAGGCC 
GAGGACGTGA GGGTGGAGGG CTCCTTTCCC GTGACCATGC TTCCGGGAGA CGGTGTGGGG 
CCTGAGCTGA TGCACGCCGT CAAGGAGGTG TTCAAGGCTG CCGCTGTCCC AGTGGAGTTC 
CAGGAGCACC ACCTGAGTGA GGTGCAGAAT ATGGCATCTG AGGAGAAGCT GGAGCAGGTG 
CTGAGTTCCA TGAAGGAGAA CAAAGTGGCC ATCATTGGAA AGATTCATAC CCCGATGGAG 
TATAAGGGGG AGCTAGCCTC CTATGATATG CGGCTGAGGC GTAAGTTGGA CTTATTTGCC 
AACGTAGTCC ATGTGAAGTC ACTTCCTGGG TATATGACTC GGCACAACAA TCTAGACCTG 
GTGATCATTC GAGAGCAGAC AGAAGGGGAG TACAGCTCTC TGGAACATGA GAGTGCAAGG 
GGTGTGATTG AGTGTTTGAA GATTGTCACA CGAGCCAAGT CTCAGCGGAT TGCAAAGTTC 
GCCTTTGACT ATGCCACCAA GAAGGGGCGG GGCAAGGTCA CTGCTGTCCA CAAGGCCAAC 
ATCATGAAAC TTGGGGATGG GTTGTTCCTG CAGTGCTGTG AGGAAGTTGC TGAACTGTAC 
CCCAAAATCA AATTTGAGAC AATGATCATA GACAACTGCT GCATGCAGCT GGTGCAGAAT 
CCTTACCAGT TTGATGTGCT TGTGATGCCC AATCTCTATG GGAACATTAT TGACAATCTG 
GCTGCTGGCC TGGTTGGGGG AGCTGGTGTG GTCCCTGGTG AGAGCTATAG TGCAGAATAC 
GCAGTCTTTG AGACGGGTGC CCGGCACCCA TTTGCCCAGG CAGTGGGCAG GAATATAGCC 
AATCCCACGG CCATGCTGCT GTCGGCTTCC AACATGCTGC GGCATCTTAA TCTTGAGTAT 
CACTCCAGCA TGATCGCAGA TGCGGTGAAG AAGGTGATCA AAGTTGGCAA GATCCCATCT 
GCTGTTCCCT CTTTCCTGCT CCATCCACTG CCCTTTTCAT GGGCCATCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IDH3B ( NM_001330763.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001317692.1 Homo sapiens isocitrate dehydrogenase 3 (NAD(+)) beta (IDH3B), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu52711
Clone ID Related Accession (Same CDS sequence)	NM_001330763.1 , NM_001330763.2
Accession Version	NM_001330763.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1164bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-24
Organism	Homo sapiens(human)
Product	isocitrate dehydrogenase [NAD] subunit beta, mitochondrial isoform e precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY131986.1, BC001960.1 and BX119223.1. On Sep 3, 2016 this sequence version replaced XM_005260716.1. Transcript Variant: This variant (5) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (e) has a longer C-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.465831.1, SRR1163658.369512.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCAT TGAGCGGAGT CCGCTGGCTG ACCCGAGCGC TGGTCTCCGC CGGGAACCCT 
GGGGCATGGA GAGGTCTGAG TACCTCGGCC GCGGCGCACG CTGCATCGCG GAGCCAGGCC 
GAGGACGTGA GGGTGGAGGG CTCCTTTCCC GTGACCATGC TTCCGGGAGA CGGTGTGGGG 
CCTGAGCTGA TGCACGCCGT CAAGGAGGTG TTCAAGGCTG CCGCTGTCCC AGTGGAGTTC 
CAGGAGCACC ACCTGAGTGA GGTGCAGAAT ATGGCATCTG AGGAGAAGCT GGAGCAGGTG 
CTGAGTTCCA TGAAGGAGAA CAAAGTGGCC ATCATTGGAA AGATTCATAC CCCGATGGAG 
TATAAGGGGG AGCTAGCCTC CTATGATATG CGGCTGAGGC GTAAGTTGGA CTTATTTGCC 
AACGTAGTCC ATGTGAAGTC ACTTCCTGGG TATATGACTC GGCACAACAA TCTAGACCTG 
GTGATCATTC GAGAGCAGAC AGAAGGGGAG TACAGCTCTC TGGAACATGA GAGTGCAAGG 
GGTGTGATTG AGTGTTTGAA GATTGTCACA CGAGCCAAGT CTCAGCGGAT TGCAAAGTTC 
GCCTTTGACT ATGCCACCAA GAAGGGGCGG GGCAAGGTCA CTGCTGTCCA CAAGGCCAAC 
ATCATGAAAC TTGGGGATGG GTTGTTCCTG CAGTGCTGTG AGGAAGTTGC TGAACTGTAC 
CCCAAAATCA AATTTGAGAC AATGATCATA GACAACTGCT GCATGCAGCT GGTGCAGAAT 
CCTTACCAGT TTGATGTGCT TGTGATGCCC AATCTCTATG GGAACATTAT TGACAATCTG 
GCTGCTGGCC TGGTTGGGGG AGCTGGTGTG GTCCCTGGTG AGAGCTATAG TGCAGAATAC 
GCAGTCTTTG AGACGGGTGC CCGGCACCCA TTTGCCCAGG CAGTGGGCAG GAATATAGCC 
AATCCCACGG CCATGCTGCT GTCGGCTTCC AACATGCTGC GGCATCTTAA TCTTGAGTAT 
CACTCCAGCA TGATCGCAGA TGCGGTGAAG AAGGTGATCA AAGTTGGCAA GGTGCGGACT 
CGAGACATGG GCGGCTACAG CACCACAACC GACTTCATCA AGTCTGTCAT CGGTCACCTG 
CAGACTAAAG GTTCGAACCT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001317692.1
CDS	36..1199
Translation	MAALSGVRWLTRALVSAGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVGPELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFIKSVIGHLQTKGSNL

Target ORF information:

RefSeq Version	NM_001330763.1
Organism	Homo sapiens(human)
Definition	Homo sapiens isocitrate dehydrogenase 3 (NAD(+)) beta (IDH3B), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001330763.1

ORF Insert Sequence:

ATGGCGGCAT TGAGCGGAGT CCGCTGGCTG ACCCGAGCGC TGGTCTCCGC CGGGAACCCT 
GGGGCATGGA GAGGTCTGAG TACCTCGGCC GCGGCGCACG CTGCATCGCG GAGCCAGGCC 
GAGGACGTGA GGGTGGAGGG CTCCTTTCCC GTGACCATGC TTCCGGGAGA CGGTGTGGGG 
CCTGAGCTGA TGCACGCCGT CAAGGAGGTG TTCAAGGCTG CCGCTGTCCC AGTGGAGTTC 
CAGGAGCACC ACCTGAGTGA GGTGCAGAAT ATGGCATCTG AGGAGAAGCT GGAGCAGGTG 
CTGAGTTCCA TGAAGGAGAA CAAAGTGGCC ATCATTGGAA AGATTCATAC CCCGATGGAG 
TATAAGGGGG AGCTAGCCTC CTATGATATG CGGCTGAGGC GTAAGTTGGA CTTATTTGCC 
AACGTAGTCC ATGTGAAGTC ACTTCCTGGG TATATGACTC GGCACAACAA TCTAGACCTG 
GTGATCATTC GAGAGCAGAC AGAAGGGGAG TACAGCTCTC TGGAACATGA GAGTGCAAGG 
GGTGTGATTG AGTGTTTGAA GATTGTCACA CGAGCCAAGT CTCAGCGGAT TGCAAAGTTC 
GCCTTTGACT ATGCCACCAA GAAGGGGCGG GGCAAGGTCA CTGCTGTCCA CAAGGCCAAC 
ATCATGAAAC TTGGGGATGG GTTGTTCCTG CAGTGCTGTG AGGAAGTTGC TGAACTGTAC 
CCCAAAATCA AATTTGAGAC AATGATCATA GACAACTGCT GCATGCAGCT GGTGCAGAAT 
CCTTACCAGT TTGATGTGCT TGTGATGCCC AATCTCTATG GGAACATTAT TGACAATCTG 
GCTGCTGGCC TGGTTGGGGG AGCTGGTGTG GTCCCTGGTG AGAGCTATAG TGCAGAATAC 
GCAGTCTTTG AGACGGGTGC CCGGCACCCA TTTGCCCAGG CAGTGGGCAG GAATATAGCC 
AATCCCACGG CCATGCTGCT GTCGGCTTCC AACATGCTGC GGCATCTTAA TCTTGAGTAT 
CACTCCAGCA TGATCGCAGA TGCGGTGAAG AAGGTGATCA AAGTTGGCAA GGTGCGGACT 
CGAGACATGG GCGGCTACAG CACCACAACC GACTTCATCA AGTCTGTCAT CGGTCACCTG 
CAGACTAAAG GTTCGAACCT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IDH3B ( NM_001330763.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001317692.1 Homo sapiens isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta (IDH3B), transcript variant 5, mRNA.

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CloneID	OHu52711
Clone ID Related Accession (Same CDS sequence)	NM_001330763.1 , NM_001330763.2
Accession Version	NM_001330763.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1164bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	isocitrate dehydrogenase [NAD] subunit beta, mitochondrial isoform e precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY131986.1, BC001960.1 and BX119223.1. On May 31, 2019 this sequence version replaced NM_001330763.1. Transcript Variant: This variant (5) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (e) has a longer C-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7346977.665014.1, SRR7410570.660108.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCAT TGAGCGGAGT CCGCTGGCTG ACCCGAGCGC TGGTCTCCGC CGGGAACCCT 
GGGGCATGGA GAGGTCTGAG TACCTCGGCC GCGGCGCACG CTGCATCGCG GAGCCAGGCC 
GAGGACGTGA GGGTGGAGGG CTCCTTTCCC GTGACCATGC TTCCGGGAGA CGGTGTGGGG 
CCTGAGCTGA TGCACGCCGT CAAGGAGGTG TTCAAGGCTG CCGCTGTCCC AGTGGAGTTC 
CAGGAGCACC ACCTGAGTGA GGTGCAGAAT ATGGCATCTG AGGAGAAGCT GGAGCAGGTG 
CTGAGTTCCA TGAAGGAGAA CAAAGTGGCC ATCATTGGAA AGATTCATAC CCCGATGGAG 
TATAAGGGGG AGCTAGCCTC CTATGATATG CGGCTGAGGC GTAAGTTGGA CTTATTTGCC 
AACGTAGTCC ATGTGAAGTC ACTTCCTGGG TATATGACTC GGCACAACAA TCTAGACCTG 
GTGATCATTC GAGAGCAGAC AGAAGGGGAG TACAGCTCTC TGGAACATGA GAGTGCAAGG 
GGTGTGATTG AGTGTTTGAA GATTGTCACA CGAGCCAAGT CTCAGCGGAT TGCAAAGTTC 
GCCTTTGACT ATGCCACCAA GAAGGGGCGG GGCAAGGTCA CTGCTGTCCA CAAGGCCAAC 
ATCATGAAAC TTGGGGATGG GTTGTTCCTG CAGTGCTGTG AGGAAGTTGC TGAACTGTAC 
CCCAAAATCA AATTTGAGAC AATGATCATA GACAACTGCT GCATGCAGCT GGTGCAGAAT 
CCTTACCAGT TTGATGTGCT TGTGATGCCC AATCTCTATG GGAACATTAT TGACAATCTG 
GCTGCTGGCC TGGTTGGGGG AGCTGGTGTG GTCCCTGGTG AGAGCTATAG TGCAGAATAC 
GCAGTCTTTG AGACGGGTGC CCGGCACCCA TTTGCCCAGG CAGTGGGCAG GAATATAGCC 
AATCCCACGG CCATGCTGCT GTCGGCTTCC AACATGCTGC GGCATCTTAA TCTTGAGTAT 
CACTCCAGCA TGATCGCAGA TGCGGTGAAG AAGGTGATCA AAGTTGGCAA GGTGCGGACT 
CGAGACATGG GCGGCTACAG CACCACAACC GACTTCATCA AGTCTGTCAT CGGTCACCTG 
CAGACTAAAG GTTCGAACCT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001317692.1
CDS	29..1192
Translation	MAALSGVRWLTRALVSAGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVGPELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFIKSVIGHLQTKGSNL

Target ORF information:

RefSeq Version	NM_001330763.2
Organism	Homo sapiens(human)
Definition	Homo sapiens isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta (IDH3B), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001330763.2

ORF Insert Sequence:

ATGGCGGCAT TGAGCGGAGT CCGCTGGCTG ACCCGAGCGC TGGTCTCCGC CGGGAACCCT 
GGGGCATGGA GAGGTCTGAG TACCTCGGCC GCGGCGCACG CTGCATCGCG GAGCCAGGCC 
GAGGACGTGA GGGTGGAGGG CTCCTTTCCC GTGACCATGC TTCCGGGAGA CGGTGTGGGG 
CCTGAGCTGA TGCACGCCGT CAAGGAGGTG TTCAAGGCTG CCGCTGTCCC AGTGGAGTTC 
CAGGAGCACC ACCTGAGTGA GGTGCAGAAT ATGGCATCTG AGGAGAAGCT GGAGCAGGTG 
CTGAGTTCCA TGAAGGAGAA CAAAGTGGCC ATCATTGGAA AGATTCATAC CCCGATGGAG 
TATAAGGGGG AGCTAGCCTC CTATGATATG CGGCTGAGGC GTAAGTTGGA CTTATTTGCC 
AACGTAGTCC ATGTGAAGTC ACTTCCTGGG TATATGACTC GGCACAACAA TCTAGACCTG 
GTGATCATTC GAGAGCAGAC AGAAGGGGAG TACAGCTCTC TGGAACATGA GAGTGCAAGG 
GGTGTGATTG AGTGTTTGAA GATTGTCACA CGAGCCAAGT CTCAGCGGAT TGCAAAGTTC 
GCCTTTGACT ATGCCACCAA GAAGGGGCGG GGCAAGGTCA CTGCTGTCCA CAAGGCCAAC 
ATCATGAAAC TTGGGGATGG GTTGTTCCTG CAGTGCTGTG AGGAAGTTGC TGAACTGTAC 
CCCAAAATCA AATTTGAGAC AATGATCATA GACAACTGCT GCATGCAGCT GGTGCAGAAT 
CCTTACCAGT TTGATGTGCT TGTGATGCCC AATCTCTATG GGAACATTAT TGACAATCTG 
GCTGCTGGCC TGGTTGGGGG AGCTGGTGTG GTCCCTGGTG AGAGCTATAG TGCAGAATAC 
GCAGTCTTTG AGACGGGTGC CCGGCACCCA TTTGCCCAGG CAGTGGGCAG GAATATAGCC 
AATCCCACGG CCATGCTGCT GTCGGCTTCC AACATGCTGC GGCATCTTAA TCTTGAGTAT 
CACTCCAGCA TGATCGCAGA TGCGGTGAAG AAGGTGATCA AAGTTGGCAA GGTGCGGACT 
CGAGACATGG GCGGCTACAG CACCACAACC GACTTCATCA AGTCTGTCAT CGGTCACCTG 
CAGACTAAAG GTTCGAACCT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Proteomic characterization of the human sperm nucleus.
Proteomics11(13)2714-26(2011 Jul)
de Mateo S,Castillo J,Estanyol JM,Ballesc? JL,Oliva R

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
PloS one5(9)e12862(2010 Sep)
Hendrickson SL,Lautenberger JA,Chinn LW,Malasky M,Sezgin E,Kingsley LA,Goedert JJ,Kirk GD,Gomperts ED,Buchbinder SP,Troyer JL,O'Brien SJ

Each conserved active site tyr in the three subunits of human isocitrate dehydrogenase has a different function.
The Journal of biological chemistry285(27)20520-5(2010 Jul)
Dange M,Colman RF

Neuro-oncology: Isocitrate dehydrogenase mutations in low-grade gliomas.
Nature reviews. Neurology5(6)303-4(2009 Jun)
Schiff D,Purow BW

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IDH3B cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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