TAS2R60 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TAS2R60
Entrez Gene ID	338398
Full Name	taste 2 receptor member 60
Synonyms	T2R56,T2R60
General protein information	Preferred Names taste 2 receptor member 60 Names taste receptor type 2 member 60 taste receptor type 2 member 56 taste receptor, type 2, member 60
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7q35
Summary	This gene encodes a member of the bitter taste receptor family which belong to the G protein-coupled receptor superfamily and are predominantly expressed in taste receptor cells of the tongue and palate epithelia. This intronless taste receptor gene encodes a seven-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered together with eight other taste receptor genes on chromosome 7. [provided by RefSeq, Jul 2017].
Disorder MIM:	613968

mRNA and Protein(s)

mRNA	Protein	Name
NM_177437.1	NP_803186.1	taste receptor type 2 member 60

Pathways from BioSystems

Homologies

Homo sapiens (human)	TAS2R60	NP_803186.1
Bos taurus (cattle)	TAS2R60	XP_002687167.1
Rattus norvegicus (Norway rat)	Tas2r135	NP_001020233.1
	TAS2R60	XP_001092105.1
Mus musculus (house mouse)	Tas2r135	NP_954610.1
Pan troglodytes (chimpanzee)	TAS2R60	NP_001009140.1

Gene Ontology
Bibliography

Related articles in PubMed

Major haplotypes of the human bitter taste receptor TAS2R41 encode functional receptors for chloramphenicol.
Thalmann S, Behrens M, Meyerhof W
Biochemical and biophysical research communications435(2)267-73(2013 May)

The molecular receptive ranges of human TAS2R bitter taste receptors.
Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, Bufe B, Appendino G, Behrens M
Chemical senses35(2)157-70(2010 Feb)

Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.
Go Y, Satta Y, Takenaka O, Takahata N
Genetics170(1)313-26(2005 May)

Evolution of bitter taste receptors in humans and apes.
Fischer A, Gilad Y, Man O, P??bo S
Molecular biology and evolution22(3)432-6(2005 Mar)

Adaptive diversification of bitter taste receptor genes in Mammalian evolution.
Shi P, Zhang J, Yang H, Zhang YP
Molecular biology and evolution20(5)805-14(2003 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following TAS2R60 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TAS2R60 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu29640	NM_177437.1 Latest version!	Homo sapiens taste 2 receptor member 60 (TAS2R60), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TAS2R60 ( NM_177437.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_803186.1 Homo sapiens taste 2 receptor member 60 (TAS2R60), mRNA.

Price & Availability↑

CloneID	OHu29640
Clone ID Related Accession (Same CDS sequence)	NM_177437.1
Accession Version	NM_177437.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 957bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-22
Organism	Homo sapiens(human)
Product	taste receptor type 2 member 60
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY114094.1. ##Evidence-Data-START## Transcript is intronless :: BC100938.2 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000332690.1/ ENSP00000327724.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGAATGGAG ACCACATGGT TCTAGGATCT TCGGTGACTG ACAAGAAGGC CATCATCTTG 
GTTACCATTT TACTCCTTTT ACGCCTGGTA GCAATAGCAG GCAATGGCTT CATCACTGCT 
GCTCTGGGCG TGGAGTGGGT GCTACGGAGA ATGTTGTTGC CTTGTGATAA GTTATTGGTT 
AGCCTAGGGG CCTCTCGCTT CTGTCTGCAG TCAGTGGTAA TGGGTAAGAC CATTTATGTT 
TTCTTGCATC CGATGGCCTT CCCATACAAC CCTGTACTGC AGTTTCTAGC TTTCCAGTGG 
GACTTCCTGA ATGCTGCCAC CTTATGGTCC TCTACCTGGC TCAGTGTCTT CTATTGTGTG 
AAAATTGCTA CCTTCACCCA CCCTGTCTTC TTCTGGCTAA AGCACAAGTT GTCTGGGTGG 
CTACCATGGA TGCTCTTCAG CTCTGTAGGG CTCTCCAGCT TCACCACCAT TCTATTTTTC 
ATAGGCAACC ACAGAATGTA TCAGAACTAT TTAAGGAACC ATCTACAACC TTGGAATGTC 
ACTGGCGATA GCATACGGAG CTACTGTGAG AAATTCTATC TCTTCCCTCT AAAAATGATT 
ACTTGGACAA TGCCCACTGC TGTCTTTTTC ATTTGCATGA TTTTGCTCAT CACATCTCTG 
GGAAGACACA GGAAGAAGGC TCTCCTTACA ACCTCAGGAT TCCGAGAGCC CAGTGTGCAG 
GCACACATAA AGGCTCTGCT GGCTCTCCTC TCTTTTGCCA TGCTCTTCAT CTCATATTTC 
CTGTCACTGG TGTTCAGTGC TGCAGGTATT TTTCCACCTC TGGACTTTAA ATTCTGGGTG 
TGGGAGTCAG TGATTTATCT GTGTGCAGCA GTTCACCCCA TCATTCTGCT CTTCAGCAAC 
TGCAGGCTGA GAGCTGTGCT GAAGAGTCGT CGTTCCTCAA GGTGTGGGAC ACCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_803186.1
CDS	1..957
Translation	MNGDHMVLGSSVTDKKAIILVTILLLLRLVAIAGNGFITAALGVEWVLRRMLLPCDKLLVSLGASRFCLQSVVMGKTIYVFLHPMAFPYNPVLQFLAFQWDFLNAATLWSSTWLSVFYCVKIATFTHPVFFWLKHKLSGWLPWMLFSSVGLSSFTTILFFIGNHRMYQNYLRNHLQPWNVTGDSIRSYCEKFYLFPLKMITWTMPTAVFFICMILLITSLGRHRKKALLTTSGFREPSVQAHIKALLALLSFAMLFISYFLSLVFSAAGIFPPLDFKFWVWESVIYLCAAVHPIILLFSNCRLRAVLKSRRSSRCGTP

Target ORF information:

RefSeq Version	NM_177437.1
Organism	Homo sapiens(human)
Definition	Homo sapiens taste 2 receptor member 60 (TAS2R60), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_177437.1

ORF Insert Sequence:

ATGAATGGAG ACCACATGGT TCTAGGATCT TCGGTGACTG ACAAGAAGGC CATCATCTTG 
GTTACCATTT TACTCCTTTT ACGCCTGGTA GCAATAGCAG GCAATGGCTT CATCACTGCT 
GCTCTGGGCG TGGAGTGGGT GCTACGGAGA ATGTTGTTGC CTTGTGATAA GTTATTGGTT 
AGCCTAGGGG CCTCTCGCTT CTGTCTGCAG TCAGTGGTAA TGGGTAAGAC CATTTATGTT 
TTCTTGCATC CGATGGCCTT CCCATACAAC CCTGTACTGC AGTTTCTAGC TTTCCAGTGG 
GACTTCCTGA ATGCTGCCAC CTTATGGTCC TCTACCTGGC TCAGTGTCTT CTATTGTGTG 
AAAATTGCTA CCTTCACCCA CCCTGTCTTC TTCTGGCTAA AGCACAAGTT GTCTGGGTGG 
CTACCATGGA TGCTCTTCAG CTCTGTAGGG CTCTCCAGCT TCACCACCAT TCTATTTTTC 
ATAGGCAACC ACAGAATGTA TCAGAACTAT TTAAGGAACC ATCTACAACC TTGGAATGTC 
ACTGGCGATA GCATACGGAG CTACTGTGAG AAATTCTATC TCTTCCCTCT AAAAATGATT 
ACTTGGACAA TGCCCACTGC TGTCTTTTTC ATTTGCATGA TTTTGCTCAT CACATCTCTG 
GGAAGACACA GGAAGAAGGC TCTCCTTACA ACCTCAGGAT TCCGAGAGCC CAGTGTGCAG 
GCACACATAA AGGCTCTGCT GGCTCTCCTC TCTTTTGCCA TGCTCTTCAT CTCATATTTC 
CTGTCACTGG TGTTCAGTGC TGCAGGTATT TTTCCACCTC TGGACTTTAA ATTCTGGGTG 
TGGGAGTCAG TGATTTATCT GTGTGCAGCA GTTCACCCCA TCATTCTGCT CTTCAGCAAC 
TGCAGGCTGA GAGCTGTGCT GAAGAGTCGT CGTTCCTCAA GGTGTGGGAC ACCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Major haplotypes of the human bitter taste receptor TAS2R41 encode functional receptors for chloramphenicol.
Biochemical and biophysical research communications435(2)267-73(2013 May)
Thalmann S,Behrens M,Meyerhof W

The molecular receptive ranges of human TAS2R bitter taste receptors.
Chemical senses35(2)157-70(2010 Feb)
Meyerhof W,Batram C,Kuhn C,Brockhoff A,Chudoba E,Bufe B,Appendino G,Behrens M

Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.
Genetics170(1)313-26(2005 May)
Go Y,Satta Y,Takenaka O,Takahata N

Evolution of bitter taste receptors in humans and apes.
Molecular biology and evolution22(3)432-6(2005 Mar)
Fischer A,Gilad Y,Man O,P??bo S

Adaptive diversification of bitter taste receptor genes in Mammalian evolution.
Molecular biology and evolution20(5)805-14(2003 May)
Shi P,Zhang J,Yang H,Zhang YP

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TAS2R60 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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