HOXD9 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	HOXD9
Entrez Gene ID	3235
Full Name	homeobox D9
Synonyms	HOX4,HOX4C,Hox-4.3,Hox-5.2
General protein information	Preferred Names homeobox D9 Names homeobox protein Hox-D9 Hox-4.3, mouse, homolog of homeo box D9 homeobox protein Hox-4C homeobox protein Hox-5.2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2q31.1
Summary	This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The exact role of this gene has not been determined. [provided by RefSeq, Jul 2008].
Disorder MIM:	142982

mRNA and Protein(s)

mRNA	Protein	Name
NM_014213.3	NP_055028.3	homeobox protein Hox-D9
NM_014213.4	NP_055028.3	homeobox protein Hox-D9

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	hoxd9a	NP_571201.3
Xenopus tropicalis (tropical clawed frog)	hoxd9	XP_002935720.2
Mus musculus (house mouse)	Hoxd9	NP_038583.1
Homo sapiens (human)	HOXD9	NP_055028.3
Pan troglodytes (chimpanzee)	HOXD9	XP_003309371.2
Rattus norvegicus (Norway rat)	Hoxd9	NP_001166940.1
Gallus gallus (chicken)	HOXD9	XP_001234507.2
Bos taurus (cattle)	HOXD9	XP_002685334.2

Gene Ontology
Bibliography

Related articles in PubMed

HOXD9 promotes epithelial-mesenchymal transition and cancer metastasis by ZEB1 regulation in hepatocellular carcinoma.
Lv X, Li L, Lv L, Qu X, Jin S, Li K, Deng X, Cheng L, He H, Dong L
Journal of experimental & clinical cancer research : CR34133(2015 Oct)

Genome-wide significant risk associations for mucinous ovarian carcinoma.
Kelemen LE, Lawrenson K, Tyrer J, Li Q, Lee JM, Seo JH, Phelan CM, Beesley J, Chen X, Spindler TJ, Aben KK, Anton-Culver H, Antonenkova N, , ,
Nature genetics47(8)888-97(2015 Aug)

Temperature dependence of internal motions of protein side-chain NH3(+) groups: insight into energy barriers for transient breakage of hydrogen bonds.
Zandarashvili L, Iwahara J
Biochemistry54(2)538-45(2015 Jan)

Histone acetylation regulates the expression of HoxD9 transcription factor in endothelial progenitor cells.
Iordache F, Constantinescu A, Andrei E, Maniu H
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie56(1)107-13(2015)

Epigenome-wide DNA methylation landscape of melanoma progression to brain metastasis reveals aberrations on homeobox D cluster associated with prognosis.
Marzese DM, Scolyer RA, Huynh JL, Huang SK, Hirose H, Chong KK, Kiyohara E, Wang J, Kawas NP, Donovan NC, Hata K, Wilmott JS, Murali R, Buckland ME, Shivalingam B, Thompson JF, Morton DL, Kelly DF, Hoon DS
Human molecular genetics23(1)226-38(2014 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

HOXD9 promotes epithelial-mesenchymal transition and cancer metastasis by ZEB1 regulation in hepatocellular carcinoma
Title: HOXD9 promotes epithelial-mesenchymal transition and cancer metastasis by ZEB1 regulation in hepatocellular carcinoma.

Data show that overexpressing homeobox D9 protein HOXD9 in mucinous ovarian carcinomas (MOCs)cells augmented the neoplastic phenotype
Title: Genome-wide significant risk associations for mucinous ovarian carcinoma.

The study investigates the temperature dependence of the internal motions of the lysine side-chain NH3(+) groups that form ion pairs with DNA phosphate groups in the HoxD9 homeodomain-DNA complex.
Title: Temperature dependence of internal motions of protein side-chain NH3(+) groups: insight into energy barriers for transient breakage of hydrogen bonds.

HoxD9 expression is regulated by histone acetylation in endothelial progenitor cells
Title: Histone acetylation regulates the expression of HoxD9 transcription factor in endothelial progenitor cells.

Results show that melanoma patients with HOXD9 hypermethylation in lymph node metastasis had poorer disease-free and overall survival.
Title: Epigenome-wide DNA methylation landscape of melanoma progression to brain metastasis reveals aberrations on homeobox D cluster associated with prognosis.

The following HOXD9 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HOXD9 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu27398	NM_014213.4 Latest version!	Homo sapiens homeobox D9 (HOXD9), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$265.30 $379.00
View Old Accession Versions >>
OHu27398	NM_014213.3	Homo sapiens homeobox D9 (HOXD9), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$265.30 $379.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

HOXD9 ( NM_014213.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_055028.3 Homo sapiens homeobox D9 (HOXD9), mRNA.

Price & Availability↑

CloneID	OHu27398
Clone ID Related Accession (Same CDS sequence)	NM_014213.3 , NM_014213.4
Accession Version	NM_014213.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1059bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	homeobox protein Hox-D9
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC044855.1, X59372.1 and BU732638.1. This sequence is a reference standard in the RefSeqGene project. On Jul 23, 2008 this sequence version replaced NM_014213.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC044855.1, X59372.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTGGGTG GGAGTGCGGG ACGCCTCAAA ATGTCTTCCA GTGGCACCCT CAGCAACTAC 
TACGTGGACT CGCTTATAGG CCATGAGGGC GACGAGGTGT TCGCGGCGCG CTTCGGGCCG 
CCGGGGCCAG GCGCGCAGGG CCGGCCTGCA GGTGTGGCTG ATGGCCCGGC CGCCACCGCC 
GCCGAGTTCG CCTCGTGTAG TTTTGCCCCC AGATCGGCCG TGTTCTCTGC CTCGTGGTCC 
GCGGTGCCCT CCCAGCCCCC GGCAGCGGCG GCGATGAGCG GCCTCTACCA CCCGTACGTT 
CCCCCGCCGC CCCTGGCCGC CTCTGCCTCC GAGCCCGGCC GCTACGTGCG CTCCTGGATG 
GAGCCGCTGC CCGGCTTCCC GGGCGGTGCG GGCGGTGGCG GTGGTGGTGG AGGCGGCGGT 
CCGGGCCGCG GTCCCAGCCC TGGCCCCAGC GGCCCAGCCA ACGGGCGCCA CTACGGGATT 
AAGCCTGAAA CCCGAGCGGC CCCGGCCCCC GCCACGGCCG CCTCCACCAC CTCCTCCTCC 
TCCACTTCCT TATCCTCCTC CTCCAAACGG ACTGAGTGCT CCGTGGCCCG GGAGTCCCAG 
GGGAGCAGCG GCCCCGAGTT CTCGTGCAAC TCGTTCCTGC AGGAGAAGGC GGCAGCGGCG 
ACGGGGGGAA CCGGGCCTGG GGCAGGGATC GGGGCCGCGA CTGGGACGGG CGGCTCGTCG 
GAGCCCTCAG CTTGCAGCGA CCACCCGATC CCAGGCTGTT CGCTGAAGGA GGAGGAGAAG 
CAGCATTCGC AGCCGCAGCA GCAGCAACTT GACCCAAACA ACCCCGCCGC GAACTGGATC 
CACGCTCGCT CCACCCGGAA AAAGCGCTGT CCCTACACCA AATACCAGAC GCTTGAGCTG 
GAGAAAGAAT TCCTCTTCAA CATGTACCTC ACCCGGGACC GGCGCTACGA GGTGGCCAGG 
ATTCTCAACC TAACAGAGAG ACAGGTCAAA ATCTGGTTTC AGAACCGTAG GATGAAAATG 
AAAAAGATGA GCAAGGAGAA ATGCCCCAAA GGAGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055028.3
CDS	85..1143
Translation	MLGGSAGRLKMSSSGTLSNYYVDSLIGHEGDEVFAARFGPPGPGAQGRPAGVADGPAATAAEFASCSFAPRSAVFSASWSAVPSQPPAAAAMSGLYHPYVPPPPLAASASEPGRYVRSWMEPLPGFPGGAGGGGGGGGGGPGRGPSPGPSGPANGRHYGIKPETRAAPAPATAASTTSSSSTSLSSSSKRTECSVARESQGSSGPEFSCNSFLQEKAAAATGGTGPGAGIGAATGTGGSSEPSACSDHPIPGCSLKEEEKQHSQPQQQQLDPNNPAANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARILNLTERQVKIWFQNRRMKMKKMSKEKCPKGD

Target ORF information:

RefSeq Version	NM_014213.3
Organism	Homo sapiens(human)
Definition	Homo sapiens homeobox D9 (HOXD9), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014213.3

ORF Insert Sequence:

ATGTTGGGTG GGAGTGCGGG ACGCCTCAAA ATGTCTTCCA GTGGCACCCT CAGCAACTAC 
TACGTGGACT CGCTTATAGG CCATGAGGGC GACGAGGTGT TCGCGGCGCG CTTCGGGCCG 
CCGGGGCCAG GCGCGCAGGG CCGGCCTGCA GGTGTGGCTG ATGGCCCGGC CGCCACCGCC 
GCCGAGTTCG CCTCGTGTAG TTTTGCCCCC AGATCGGCCG TGTTCTCTGC CTCGTGGTCC 
GCGGTGCCCT CCCAGCCCCC GGCAGCGGCG GCGATGAGCG GCCTCTACCA CCCGTACGTT 
CCCCCGCCGC CCCTGGCCGC CTCTGCCTCC GAGCCCGGCC GCTACGTGCG CTCCTGGATG 
GAGCCGCTGC CCGGCTTCCC GGGCGGTGCG GGCGGTGGCG GTGGTGGTGG AGGCGGCGGT 
CCGGGCCGCG GTCCCAGCCC TGGCCCCAGC GGCCCAGCCA ACGGGCGCCA CTACGGGATT 
AAGCCTGAAA CCCGAGCGGC CCCGGCCCCC GCCACGGCCG CCTCCACCAC CTCCTCCTCC 
TCCACTTCCT TATCCTCCTC CTCCAAACGG ACTGAGTGCT CCGTGGCCCG GGAGTCCCAG 
GGGAGCAGCG GCCCCGAGTT CTCGTGCAAC TCGTTCCTGC AGGAGAAGGC GGCAGCGGCG 
ACGGGGGGAA CCGGGCCTGG GGCAGGGATC GGGGCCGCGA CTGGGACGGG CGGCTCGTCG 
GAGCCCTCAG CTTGCAGCGA CCACCCGATC CCAGGCTGTT CGCTGAAGGA GGAGGAGAAG 
CAGCATTCGC AGCCGCAGCA GCAGCAACTT GACCCAAACA ACCCCGCCGC GAACTGGATC 
CACGCTCGCT CCACCCGGAA AAAGCGCTGT CCCTACACCA AATACCAGAC GCTTGAGCTG 
GAGAAAGAAT TCCTCTTCAA CATGTACCTC ACCCGGGACC GGCGCTACGA GGTGGCCAGG 
ATTCTCAACC TAACAGAGAG ACAGGTCAAA ATCTGGTTTC AGAACCGTAG GATGAAAATG 
AAAAAGATGA GCAAGGAGAA ATGCCCCAAA GGAGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HOXD9 ( NM_014213.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_055028.3 Homo sapiens homeobox D9 (HOXD9), mRNA.

Price & Availability↑

CloneID	OHu27398
Clone ID Related Accession (Same CDS sequence)	NM_014213.3 , NM_014213.4
Accession Version	NM_014213.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1059bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Homo sapiens(human)
Product	homeobox protein Hox-D9
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC044855.1, X59372.1, BU732638.1 and AC009336.13. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_014213.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC044855.1, X59372.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000249499.8/ ENSP00000249499.6 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTTGGGTG GGAGTGCGGG ACGCCTCAAA ATGTCTTCCA GTGGCACCCT CAGCAACTAC 
TACGTGGACT CGCTTATAGG CCATGAGGGC GACGAGGTGT TCGCGGCGCG CTTCGGGCCG 
CCGGGGCCAG GCGCGCAGGG CCGGCCTGCA GGTGTGGCTG ATGGCCCGGC CGCCACCGCC 
GCCGAGTTCG CCTCGTGTAG TTTTGCCCCC AGATCGGCCG TGTTCTCTGC CTCGTGGTCC 
GCGGTGCCCT CCCAGCCCCC GGCAGCGGCG GCGATGAGCG GCCTCTACCA CCCGTACGTT 
CCCCCGCCGC CCCTGGCCGC CTCTGCCTCC GAGCCCGGCC GCTACGTGCG CTCCTGGATG 
GAGCCGCTGC CCGGCTTCCC GGGCGGTGCG GGCGGTGGCG GTGGTGGTGG AGGCGGCGGT 
CCGGGCCGCG GTCCCAGCCC TGGCCCCAGC GGCCCAGCCA ACGGGCGCCA CTACGGGATT 
AAGCCTGAAA CCCGAGCGGC CCCGGCCCCC GCCACGGCCG CCTCCACCAC CTCCTCCTCC 
TCCACTTCCT TATCCTCCTC CTCCAAACGG ACTGAGTGCT CCGTGGCCCG GGAGTCCCAG 
GGGAGCAGCG GCCCCGAGTT CTCGTGCAAC TCGTTCCTGC AGGAGAAGGC GGCAGCGGCG 
ACGGGGGGAA CCGGGCCTGG GGCAGGGATC GGGGCCGCGA CTGGGACGGG CGGCTCGTCG 
GAGCCCTCAG CTTGCAGCGA CCACCCGATC CCAGGCTGTT CGCTGAAGGA GGAGGAGAAG 
CAGCATTCGC AGCCGCAGCA GCAGCAACTT GACCCAAACA ACCCCGCCGC GAACTGGATC 
CACGCTCGCT CCACCCGGAA AAAGCGCTGT CCCTACACCA AATACCAGAC GCTTGAGCTG 
GAGAAAGAAT TCCTCTTCAA CATGTACCTC ACCCGGGACC GGCGCTACGA GGTGGCCAGG 
ATTCTCAACC TAACAGAGAG ACAGGTCAAA ATCTGGTTTC AGAACCGTAG GATGAAAATG 
AAAAAGATGA GCAAGGAGAA ATGCCCCAAA GGAGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055028.3
CDS	51..1109
Translation	MLGGSAGRLKMSSSGTLSNYYVDSLIGHEGDEVFAARFGPPGPGAQGRPAGVADGPAATAAEFASCSFAPRSAVFSASWSAVPSQPPAAAAMSGLYHPYVPPPPLAASASEPGRYVRSWMEPLPGFPGGAGGGGGGGGGGPGRGPSPGPSGPANGRHYGIKPETRAAPAPATAASTTSSSSTSLSSSSKRTECSVARESQGSSGPEFSCNSFLQEKAAAATGGTGPGAGIGAATGTGGSSEPSACSDHPIPGCSLKEEEKQHSQPQQQQLDPNNPAANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARILNLTERQVKIWFQNRRMKMKKMSKEKCPKGD

Target ORF information:

RefSeq Version	NM_014213.4
Organism	Homo sapiens(human)
Definition	Homo sapiens homeobox D9 (HOXD9), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014213.4

ORF Insert Sequence:

ATGTTGGGTG GGAGTGCGGG ACGCCTCAAA ATGTCTTCCA GTGGCACCCT CAGCAACTAC 
TACGTGGACT CGCTTATAGG CCATGAGGGC GACGAGGTGT TCGCGGCGCG CTTCGGGCCG 
CCGGGGCCAG GCGCGCAGGG CCGGCCTGCA GGTGTGGCTG ATGGCCCGGC CGCCACCGCC 
GCCGAGTTCG CCTCGTGTAG TTTTGCCCCC AGATCGGCCG TGTTCTCTGC CTCGTGGTCC 
GCGGTGCCCT CCCAGCCCCC GGCAGCGGCG GCGATGAGCG GCCTCTACCA CCCGTACGTT 
CCCCCGCCGC CCCTGGCCGC CTCTGCCTCC GAGCCCGGCC GCTACGTGCG CTCCTGGATG 
GAGCCGCTGC CCGGCTTCCC GGGCGGTGCG GGCGGTGGCG GTGGTGGTGG AGGCGGCGGT 
CCGGGCCGCG GTCCCAGCCC TGGCCCCAGC GGCCCAGCCA ACGGGCGCCA CTACGGGATT 
AAGCCTGAAA CCCGAGCGGC CCCGGCCCCC GCCACGGCCG CCTCCACCAC CTCCTCCTCC 
TCCACTTCCT TATCCTCCTC CTCCAAACGG ACTGAGTGCT CCGTGGCCCG GGAGTCCCAG 
GGGAGCAGCG GCCCCGAGTT CTCGTGCAAC TCGTTCCTGC AGGAGAAGGC GGCAGCGGCG 
ACGGGGGGAA CCGGGCCTGG GGCAGGGATC GGGGCCGCGA CTGGGACGGG CGGCTCGTCG 
GAGCCCTCAG CTTGCAGCGA CCACCCGATC CCAGGCTGTT CGCTGAAGGA GGAGGAGAAG 
CAGCATTCGC AGCCGCAGCA GCAGCAACTT GACCCAAACA ACCCCGCCGC GAACTGGATC 
CACGCTCGCT CCACCCGGAA AAAGCGCTGT CCCTACACCA AATACCAGAC GCTTGAGCTG 
GAGAAAGAAT TCCTCTTCAA CATGTACCTC ACCCGGGACC GGCGCTACGA GGTGGCCAGG 
ATTCTCAACC TAACAGAGAG ACAGGTCAAA ATCTGGTTTC AGAACCGTAG GATGAAAATG 
AAAAAGATGA GCAAGGAGAA ATGCCCCAAA GGAGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

HOXD9 promotes epithelial-mesenchymal transition and cancer metastasis by ZEB1 regulation in hepatocellular carcinoma.
Journal of experimental & clinical cancer research : CR34133(2015 Oct)
Lv X,Li L,Lv L,Qu X,Jin S,Li K,Deng X,Cheng L,He H,Dong L

Genome-wide significant risk associations for mucinous ovarian carcinoma.
Nature genetics47(8)888-97(2015 Aug)
Kelemen LE,Lawrenson K,Tyrer J,Li Q,Lee JM,Seo JH,Phelan CM,Beesley J,Chen X,Spindler TJ,Aben KK,Anton-Culver H,Antonenkova N,,,

Temperature dependence of internal motions of protein side-chain NH3(+) groups: insight into energy barriers for transient breakage of hydrogen bonds.
Biochemistry54(2)538-45(2015 Jan)
Zandarashvili L,Iwahara J

Histone acetylation regulates the expression of HoxD9 transcription factor in endothelial progenitor cells.
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie56(1)107-13(2015)
Iordache F,Constantinescu A,Andrei E,Maniu H

Epigenome-wide DNA methylation landscape of melanoma progression to brain metastasis reveals aberrations on homeobox D cluster associated with prognosis.
Human molecular genetics23(1)226-38(2014 Jan)
Marzese DM,Scolyer RA,Huynh JL,Huang SK,Hirose H,Chong KK,Kiyohara E,Wang J,Kawas NP,Donovan NC,Hata K,Wilmott JS,Murali R,Buckland ME,Shivalingam B,Thompson JF,Morton DL,Kelly DF,Hoon DS

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HOXD9 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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