TAAR6 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TAAR6
Entrez Gene ID	319100
Full Name	trace amine associated receptor 6
Synonyms	TA4,TAR4,TAR6,TRAR4,taR-4,taR-6
General protein information	Preferred Names trace amine associated receptor 6 Names trace amine-associated receptor 6 trace amine receptor 4 trace amine receptor 6
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6q23.2
Summary	This gene encodes a seven-transmembrane G-protein-coupled receptor that likely functions as a receptor for endogenous trace amines. Mutations in this gene may be associated with schizophrenia.[provided by RefSeq, Feb 2010].
Disorder MIM:	608923

mRNA and Protein(s)

mRNA	Protein	Name
NM_175067.1	NP_778237.1	trace amine-associated receptor 6

Pathways from BioSystems

Homologies

	TAAR6	NP_001107583.1
Bos taurus (cattle)	TAAR6	NP_001193494.1
Mus musculus (house mouse)	Taar6	NP_001010828.1
Homo sapiens (human)	TAAR6	NP_778237.1
Bos taurus (cattle)	LOC616737	XP_002690274.1
Pan troglodytes (chimpanzee)	TAAR6	NP_001009125.1
Bos taurus (cattle)	LOC785236	XP_003586525.1
Bos taurus (cattle)	LOC511136	XP_002690273.1
Bos taurus (cattle)	LOC783649	XP_002707885.1
Rattus norvegicus (Norway rat)	Taar6	NP_783174.1
Bos taurus (cattle)	LOC785080	XP_002690302.1

Gene Ontology
Bibliography

Related articles in PubMed

Association between TAAR6 polymorphisms and airway responsiveness to inhaled corticosteroids in asthmatic patients.
Chang HS, Heo JS, Shin SW, Bae DJ, Song HJ, Jun JA, Kim JD, Park JS, Park BL, Shin HD, Park CS
Pharmacogenetics and genomics25(7)334-42(2015 Jul)

TAAR6 variations possibly associated with antidepressant response and suicidal behavior.
Pae CU, Drago A, Kim JJ, Patkar AA, Jun TY, De Ronchi D, Serretti A
Psychiatry research180(1)20-4(2010 Nov)

Epistasis between a set of variations located in the TAAR6 and HSP-70 genes toward schizophrenia and response to antipsychotic treatment.
Pae CU, Drago A, Patkar AA, Jun TY, Serretti A
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology19(11)806-11(2009 Nov)

TAAR 6 and HSP-70 variations associated with bipolar disorder.
Pae CU, Drago A, Mandelli L, De Ronchi D, Serretti A
Neuroscience letters465(3)257-61(2009 Nov)

Failure to find association between TRAR4 and schizophrenia in the Chinese Han population.
Duan S, Du J, Xu Y, Xing Q, Wang H, Wu S, Chen Q, Li X, Li X, Shen J, Feng G, He L
Journal of neural transmission (Vienna, Austria : 1996)113(3)381-5(2006 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Among the 15 SNPs and seven haplotypes of TAAR6, rs7772821 (T>G) on the 3'-UTR showed the strongest correlation with inhaled corticosteroid-induced %DeltaFEV1 in asthmatics.
Title: Association between TAAR6 polymorphisms and airway responsiveness to inhaled corticosteroids in asthmatic patients.

Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: TAAR6 variations possibly associated with antidepressant response and suicidal behavior.

an epistastic effect between a set of TAAR6 and HSP-70 gene variations has a role in major mood disorders
Title: Investigation of an epistastic effect between a set of TAAR6 and HSP-70 genes variations and major mood disorders.

Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Epistasis between a set of variations located in the TAAR6 and HSP-70 genes toward schizophrenia and response to antipsychotic treatment.

This study provides preliminary evidence that HSP-70 may play a role in the disrupted mechanisms that lead to BPD.
Title: TAAR 6 and HSP-70 variations associated with bipolar disorder.

The following TAAR6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TAAR6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu19297	NM_175067.1 Latest version!	Homo sapiens trace amine associated receptor 6 (TAAR6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$144.50-$202.30 $289.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TAAR6 ( NM_175067.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_778237.1 Homo sapiens trace amine associated receptor 6 (TAAR6), mRNA.

Price & Availability↑

CloneID	OHu19297
Clone ID Related Accession (Same CDS sequence)	NM_175067.1
Accession Version	NM_175067.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1038bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-29
Organism	Homo sapiens(human)
Product	trace amine-associated receptor 6
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY183470.1. This sequence is a reference standard in the RefSeqGene project. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: BC069157.1, AY183470.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000275198.1/ ENSP00000275198.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGAGCAGCA ATTCATCCCT GCTGGTGGCT GTGCAGCTGT GCTACGCGAA CGTGAATGGG 
TCCTGTGTGA AAATCCCCTT CTCGCCGGGA TCCCGGGTGA TTCTGTACAT AGTGTTTGGC 
TTTGGGGCTG TGCTGGCTGT GTTTGGAAAC CTCCTGGTGA TGATTTCAAT CCTCCATTTC 
AAGCAGCTGC ACTCTCCGAC CAATTTTCTC GTTGCCTCTC TGGCCTGCGC TGATTTCTTG 
GTGGGTGTGA CTGTGATGCC CTTCAGCATG GTCAGGACGG TGGAGAGCTG CTGGTATTTT 
GGGAGGAGTT TTTGTACTTT CCACACCTGC TGTGATGTGG CATTTTGTTA CTCTTCTCTC 
TTTCACTTGT GCTTCATCTC CATCGACAGG TACATTGCGG TTACTGACCC CCTGGTCTAT 
CCTACCAAGT TCACCGTATC TGTGTCAGGA ATTTGCATCA GCGTGTCCTG GATCCTGCCC 
CTCATGTACA GCGGTGCTGT GTTCTACACA GGTGTCTATG ACGATGGGCT GGAGGAATTA 
TCTGATGCCC TAAACTGTAT AGGAGGTTGT CAGACCGTTG TAAATCAAAA CTGGGTGTTG 
ACAGATTTTC TATCCTTCTT TATACCTACC TTTATTATGA TAATTCTGTA TGGTAACATA 
TTTCTTGTGG CTAGACGACA GGCGAAAAAG ATAGAAAATA CTGGTAGCAA GACAGAATCA 
TCCTCAGAGA GTTACAAAGC CAGAGTGGCC AGGAGAGAGA GAAAAGCAGC TAAAACCCTG 
GGGGTCACAG TGGTAGCATT TATGATTTCA TGGTTACCAT ATAGCATTGA TTCATTAATT 
GATGCCTTTA TGGGCTTTAT AACCCCTGCC TGTATTTATG AGATTTGCTG TTGGTGTGCT 
TATTATAACT CAGCCATGAA TCCTTTGATT TATGCTTTAT TTTACCCATG GTTTAGGAAA 
GCAATAAAAG TTATTGTAAC TGGTCAGGTT TTAAAGAACA GTTCAGCAAC CATGAATTTG 
TTTTCTGAAC ATATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_778237.1
CDS	1..1038
Translation	MSSNSSLLVAVQLCYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHFKQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEELSDALNCIGGCQTVVNQNWVLTDFLSFFIPTFIMIILYGNIFLVARRQAKKIENTGSKTESSSESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCAYYNSAMNPLIYALFYPWFRKAIKVIVTGQVLKNSSATMNLFSEHI

Target ORF information:

RefSeq Version	NM_175067.1
Organism	Homo sapiens(human)
Definition	Homo sapiens trace amine associated receptor 6 (TAAR6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_175067.1

ORF Insert Sequence:

ATGAGCAGCA ATTCATCCCT GCTGGTGGCT GTGCAGCTGT GCTACGCGAA CGTGAATGGG 
TCCTGTGTGA AAATCCCCTT CTCGCCGGGA TCCCGGGTGA TTCTGTACAT AGTGTTTGGC 
TTTGGGGCTG TGCTGGCTGT GTTTGGAAAC CTCCTGGTGA TGATTTCAAT CCTCCATTTC 
AAGCAGCTGC ACTCTCCGAC CAATTTTCTC GTTGCCTCTC TGGCCTGCGC TGATTTCTTG 
GTGGGTGTGA CTGTGATGCC CTTCAGCATG GTCAGGACGG TGGAGAGCTG CTGGTATTTT 
GGGAGGAGTT TTTGTACTTT CCACACCTGC TGTGATGTGG CATTTTGTTA CTCTTCTCTC 
TTTCACTTGT GCTTCATCTC CATCGACAGG TACATTGCGG TTACTGACCC CCTGGTCTAT 
CCTACCAAGT TCACCGTATC TGTGTCAGGA ATTTGCATCA GCGTGTCCTG GATCCTGCCC 
CTCATGTACA GCGGTGCTGT GTTCTACACA GGTGTCTATG ACGATGGGCT GGAGGAATTA 
TCTGATGCCC TAAACTGTAT AGGAGGTTGT CAGACCGTTG TAAATCAAAA CTGGGTGTTG 
ACAGATTTTC TATCCTTCTT TATACCTACC TTTATTATGA TAATTCTGTA TGGTAACATA 
TTTCTTGTGG CTAGACGACA GGCGAAAAAG ATAGAAAATA CTGGTAGCAA GACAGAATCA 
TCCTCAGAGA GTTACAAAGC CAGAGTGGCC AGGAGAGAGA GAAAAGCAGC TAAAACCCTG 
GGGGTCACAG TGGTAGCATT TATGATTTCA TGGTTACCAT ATAGCATTGA TTCATTAATT 
GATGCCTTTA TGGGCTTTAT AACCCCTGCC TGTATTTATG AGATTTGCTG TTGGTGTGCT 
TATTATAACT CAGCCATGAA TCCTTTGATT TATGCTTTAT TTTACCCATG GTTTAGGAAA 
GCAATAAAAG TTATTGTAAC TGGTCAGGTT TTAAAGAACA GTTCAGCAAC CATGAATTTG 
TTTTCTGAAC ATATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Association between TAAR6 polymorphisms and airway responsiveness to inhaled corticosteroids in asthmatic patients.
Pharmacogenetics and genomics25(7)334-42(2015 Jul)
Chang HS,Heo JS,Shin SW,Bae DJ,Song HJ,Jun JA,Kim JD,Park JS,Park BL,Shin HD,Park CS

TAAR6 variations possibly associated with antidepressant response and suicidal behavior.
Psychiatry research180(1)20-4(2010 Nov)
Pae CU,Drago A,Kim JJ,Patkar AA,Jun TY,De Ronchi D,Serretti A

Epistasis between a set of variations located in the TAAR6 and HSP-70 genes toward schizophrenia and response to antipsychotic treatment.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology19(11)806-11(2009 Nov)
Pae CU,Drago A,Patkar AA,Jun TY,Serretti A

TAAR 6 and HSP-70 variations associated with bipolar disorder.
Neuroscience letters465(3)257-61(2009 Nov)
Pae CU,Drago A,Mandelli L,De Ronchi D,Serretti A

Failure to find association between TRAR4 and schizophrenia in the Chinese Han population.
Journal of neural transmission (Vienna, Austria : 1996)113(3)381-5(2006 Mar)
Duan S,Du J,Xu Y,Xing Q,Wang H,Wu S,Chen Q,Li X,Li X,Shen J,Feng G,He L

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TAAR6 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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