NRG1 cDNA ORF clone, Homo sapiens(human)

The following NRG1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NRG1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu28421 NM_001160001.3
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta1d, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$249.50-$349.30
$499.00
OHu28423 NM_013957.5
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta2, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$49.50-$69.30
$99.00
OHu28437 NM_013964.5
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-alpha, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$189.50-$265.30
$379.00
OHu28439 NM_001159995.3
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta1c, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$254.50-$356.30
$509.00
OHu28441 NM_013956.5
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta1, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$219.50-$307.30
$439.00
OHu28453 NM_001160008.2
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta2b, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$174.50-$244.30
$349.00
OHu28457 NM_001159999.3
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta1b, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$49.50-$69.30
$99.00
OHu42053 NM_001322205.2
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant NRG-III-beta1a, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$279.50-$391.30
$559.00
OHu42056 XM_006716335.3
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant X13, mRNA. pcDNA3.1-C-(k)DYK or customized vector 5-7 $223.30
$319.00
OHu102675 NM_001322202.2
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant fetal-c-IV-2, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $223.30
$319.00
OHu102675 NM_001322201.2
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant fetal-a-IV-1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $223.30
$319.00
OHu28420 NM_001160005.1
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta3b, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $188.30
$269.00
OHu28425 NM_004495.4
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-gamma, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $188.30
$269.00
OHu28427 NM_013959.3
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant SMDF, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $216.30
$309.00
OHu28430 NM_001160002.2
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-gamma2, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $69.30
$99.00
OHu28432 NM_013960.5
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant ndf43, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $223.30
$319.00
OHu28433 NM_001160007.2
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-gamma3, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $69.30
$99.00
OHu28442 NM_001160004.3
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant ndf43b, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $272.30
$389.00
OHu28447 NM_013958.3
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta3, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $188.30
$269.00
OHu28451 NM_001159996.2
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant ndf43c, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $139.30
$199.00
OHu58208 NM_001322206.2
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant III-2, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $307.30
$439.00
OHu58207 XM_011544512.2
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant X8, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $307.30
$439.00
OHu102686 NM_001322207.2
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant III-3, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $223.30
$319.00
OHu102719 NM_001322197.2
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant VI-1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $223.30
$319.00
OHu97937 XM_017013369.2
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant X9, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $223.30
$319.00
OHu97938 XM_017013370.1
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant X10, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $223.30
$319.00
OHu97939 XM_017013371.2
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant X11, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $223.30
$319.00
OHu97940 XM_017013372.2
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant X12, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $223.30
$319.00
OHu42054 XM_005273486.3
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 12-14 $391.30
$559.00
OHu42055 XM_005273487.3
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant X2, mRNA. pcDNA3.1-C-(k)DYK or customized vector 12-14 $391.30
$559.00
OHu106016 XM_024447143.1
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant X7, mRNA. pcDNA3.1-C-(k)DYK or customized vector 14-16 $307.30
$439.00
OHu97933 XM_017013365.2
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant X3, mRNA. pcDNA3.1-C-(k)DYK or customized vector 14-16 $307.30
$439.00
OHu97934 XM_017013366.2
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant X4, mRNA. pcDNA3.1-C-(k)DYK or customized vector 14-16 $307.30
$439.00
OHu97935 XM_017013367.1
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant X5, mRNA. pcDNA3.1-C-(k)DYK or customized vector 14-16 $307.30
$439.00
OHu97936 XM_017013368.2
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant X6, mRNA. pcDNA3.1-C-(k)DYK or customized vector 14-16 $307.30
$439.00
OHu28449 NM_013962.2
Latest version!
Homo sapiens neuregulin 1 (NRG1), transcript variant GGF2, mRNA. pcDNA3.1-C-(k)DYK or customized vector TBD $244.30
$349.00
View Old Accession Versions >>
OHu28421 NM_001160001.1 Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta1d, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$249.50-$349.30
$499.00
OHu28437 NM_013964.3 Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-alpha, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$189.50-$265.30
$379.00
OHu28421 NM_001160001.2 Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta1d, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$249.50-$349.30
$499.00
OHu28423 NM_013957.4 Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta2, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$49.50-$69.30
$99.00
OHu102719 NM_001322197.1 Homo sapiens neuregulin 1 (NRG1), transcript variant VI-1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $223.30
$319.00
OHu97937 XM_017013369.1 Homo sapiens neuregulin 1 (NRG1), transcript variant X8, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $223.30
$319.00
OHu28430 NM_001160002.1 Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-gamma2, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $69.30
$99.00
OHu97940 XM_017013372.1 Homo sapiens neuregulin 1 (NRG1), transcript variant X11, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $223.30
$319.00
OHu28457 NM_001159999.1 Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta1b, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$49.50-$69.30
$99.00
OHu28441 NM_013956.3 Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta1, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$219.50-$307.30
$439.00
OHu28457 NM_001159999.2 Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta1b, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$49.50-$69.30
$99.00
OHu28437 NM_013964.4 Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-alpha, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$189.50-$265.30
$379.00
OHu97933 XM_017013365.1 Homo sapiens neuregulin 1 (NRG1), transcript variant X3, mRNA. pcDNA3.1-C-(k)DYK or customized vector 14-16 $307.30
$439.00
OHu42053 NM_001322205.1 Homo sapiens neuregulin 1 (NRG1), transcript variant NRG-III-beta1a, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$279.50-$391.30
$559.00
OHu28433 NM_001160007.1 Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-gamma3, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $69.30
$99.00
OHu28425 NM_004495.3 Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-gamma, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $188.30
$269.00
OHu97934 XM_017013366.1 Homo sapiens neuregulin 1 (NRG1), transcript variant X4, mRNA. pcDNA3.1-C-(k)DYK or customized vector 14-16 $307.30
$439.00
OHu97936 XM_017013368.1 Homo sapiens neuregulin 1 (NRG1), transcript variant X6, mRNA. pcDNA3.1-C-(k)DYK or customized vector 14-16 $307.30
$439.00
OHu28432 NM_013960.4 Homo sapiens neuregulin 1 (NRG1), transcript variant ndf43, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $223.30
$319.00
OHu97939 XM_017013371.1 Homo sapiens neuregulin 1 (NRG1), transcript variant X10, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $223.30
$319.00
OHu28423 NM_013957.3 Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta2, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$49.50-$69.30
$99.00
OHu102675 NM_001322202.1 Homo sapiens neuregulin 1 (NRG1), transcript variant fetal-c-IV-2, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $223.30
$319.00
OHu28453 NM_001160008.1 Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta2b, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$174.50-$244.30
$349.00
OHu28439 NM_001159995.1 Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta1c, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$254.50-$356.30
$509.00
OHu102675 NM_001322201.1 Homo sapiens neuregulin 1 (NRG1), transcript variant fetal-a-IV-1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $223.30
$319.00
OHu58208 NM_001322206.1 Homo sapiens neuregulin 1 (NRG1), transcript variant III-2, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $307.30
$439.00
OHu28441 NM_013956.4 Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta1, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$219.50-$307.30
$439.00
OHu28442 NM_001160004.2 Homo sapiens neuregulin 1 (NRG1), transcript variant ndf43b, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $272.30
$389.00
OHu28439 NM_001159995.2 Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta1c, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$254.50-$356.30
$509.00
OHu102686 NM_001322207.1 Homo sapiens neuregulin 1 (NRG1), transcript variant III-3, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $223.30
$319.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

  • Reference Sequences (Refseq)
    CloneID OHu28421
    Clone ID Related Accession (Same CDS sequence) NM_001160001.1 , NM_001160001.3 , NM_001160001.2
    Accession Version NM_001160001.1 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1773bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2014-06-23
    Organism Homo sapiens(Human)
    Product pro-neuregulin-1, membrane-bound isoform isoform HRG-beta1d
    Comment

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    ATGGGGAAAG GACGCGCGGG CCGAGTTGGC ACCACAGCCT TGCCTCCCCG ATTGAAAGAG 
    ATGAAAAGCC AGGAATCGGC TGCAGGTTCC AAACTAGTCC TTCGGTGTGA AACCAGTTCT
    GAATACTCCT CTCTCAGATT CAAGTGGTTC AAGAATGGGA ATGAATTGAA TCGAAAAAAC
    AAACCACAAA ATATCAAGAT ACAAAAAAAG CCAGGGAAGT CAGAACTTCG CATTAACAAA
    GCATCACTGG CTGATTCTGG AGAGTATATG TGCAAAGTGA TCAGCAAATT AGGAAATGAC
    AGTGCCTCTG CCAATATCAC CATCGTGGAA TCAAACGCTA CATCTACATC CACCACTGGG
    ACAAGCCATC TTGTAAAATG TGCGGAGAAG GAGAAAACTT TCTGTGTGAA TGGAGGGGAG
    TGCTTCATGG TGAAAGACCT TTCAAACCCC TCGAGATACT TGTGCAAGTG CCCAAATGAG
    TTTACTGGTG ATCGCTGCCA AAACTACGTA ATGGCCAGCT TCTACAAGCA TCTTGGGATT
    GAATTTATGG AGGCGGAGGA GCTGTACCAG AAGAGAGTGC TGACCATAAC CGGCATCTGC
    ATCGCCCTCC TTGTGGTCGG CATCATGTGT GTGGTGGCCT ACTGCAAAAC CAAGAAACAG
    CGGAAAAAGC TGCATGACCG TCTTCGGCAG AGCCTTCGGT CTGAACGAAA CAATATGATG
    AACATTGCCA ATGGGCCTCA CCATCCTAAC CCACCCCCCG AGAATGTCCA GCTGGTGAAT
    CAATACGTAT CTAAAAACGT CATCTCCAGT GAGCATATTG TTGAGAGAGA AGCAGAGACA
    TCCTTTTCCA CCAGTCACTA TACTTCCACA GCCCATCACT CCACTACTGT CACCCAGACT
    CCTAGCCACA GCTGGAGCAA CGGACACACT GAAAGCATCC TTTCCGAAAG CCACTCTGTA
    ATCGTGATGT CATCCGTAGA AAACAGTAGG CACAGCAGCC CAACTGGGGG CCCAAGAGGA
    CGTCTTAATG GCACAGGAGG CCCTCGTGAA TGTAACAGCT TCCTCAGGCA TGCCAGAGAA
    ACCCCTGATT CCTACCGAGA CTCTCCTCAT AGTGAAAGGT ATGTGTCAGC CATGACCACC
    CCGGCTCGTA TGTCACCTGT AGATTTCCAC ACGCCAAGCT CCCCCAAATC GCCCCCTTCG
    GAAATGTCTC CACCCGTGTC CAGCATGACG GTGTCCATGC CTTCCATGGC GGTCAGCCCC
    TTCATGGAAG AAGAGAGACC TCTACTTCTC GTGACACCAC CAAGGCTGCG GGAGAAGAAG
    TTTGACCATC ACCCTCAGCA GTTCAGCTCC TTCCACCACA ACCCCGCGCA TGACAGTAAC
    AGCCTCCCTG CTAGCCCCTT GAGGATAGTG GAGGATGAGG AGTATGAAAC GACCCAAGAG
    TACGAGCCAG CCCAAGAGCC TGTTAAGAAA CTCGCCAATA GCCGGCGGGC CAAAAGAACC
    AAGCCCAATG GCCACATTGC TAACAGATTG GAAGTGGACA GCAACACAAG CTCCCAGAGC
    AGTAACTCAG AGAGTGAAAC AGAAGATGAA AGAGTAGGTG AAGATACGCC TTTCCTGGGC
    ATACAGAACC CCCTGGCAGC CAGTCTTGAG GCAACACCTG CCTTCCGCCT GGCTGACAGC
    AGGACTAACC CAGCAGGCCG CTTCTCGACA CAGGAAGAAA TCCAGGCCAG GCTGTCTAGT
    GTAATTGCTA ACCAAGACCC TATTGCTGTA TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001153473.1
    Translation

    Target ORF information:

    RefSeq Version NM_001160001.1
    Organism Homo sapiens(Human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta1d, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001160001.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    ATGGGGAAAG GACGCGCGGG CCGAGTTGGC ACCACAGCCT TGCCTCCCCG ATTGAAAGAG 
    ATGAAAAGCC AGGAATCGGC TGCAGGTTCC AAACTAGTCC TTCGGTGTGA AACCAGTTCT
    GAATACTCCT CTCTCAGATT CAAGTGGTTC AAGAATGGGA ATGAATTGAA TCGAAAAAAC
    AAACCACAAA ATATCAAGAT ACAAAAAAAG CCAGGGAAGT CAGAACTTCG CATTAACAAA
    GCATCACTGG CTGATTCTGG AGAGTATATG TGCAAAGTGA TCAGCAAATT AGGAAATGAC
    AGTGCCTCTG CCAATATCAC CATCGTGGAA TCAAACGCTA CATCTACATC CACCACTGGG
    ACAAGCCATC TTGTAAAATG TGCGGAGAAG GAGAAAACTT TCTGTGTGAA TGGAGGGGAG
    TGCTTCATGG TGAAAGACCT TTCAAACCCC TCGAGATACT TGTGCAAGTG CCCAAATGAG
    TTTACTGGTG ATCGCTGCCA AAACTACGTA ATGGCCAGCT TCTACAAGCA TCTTGGGATT
    GAATTTATGG AGGCGGAGGA GCTGTACCAG AAGAGAGTGC TGACCATAAC CGGCATCTGC
    ATCGCCCTCC TTGTGGTCGG CATCATGTGT GTGGTGGCCT ACTGCAAAAC CAAGAAACAG
    CGGAAAAAGC TGCATGACCG TCTTCGGCAG AGCCTTCGGT CTGAACGAAA CAATATGATG
    AACATTGCCA ATGGGCCTCA CCATCCTAAC CCACCCCCCG AGAATGTCCA GCTGGTGAAT
    CAATACGTAT CTAAAAACGT CATCTCCAGT GAGCATATTG TTGAGAGAGA AGCAGAGACA
    TCCTTTTCCA CCAGTCACTA TACTTCCACA GCCCATCACT CCACTACTGT CACCCAGACT
    CCTAGCCACA GCTGGAGCAA CGGACACACT GAAAGCATCC TTTCCGAAAG CCACTCTGTA
    ATCGTGATGT CATCCGTAGA AAACAGTAGG CACAGCAGCC CAACTGGGGG CCCAAGAGGA
    CGTCTTAATG GCACAGGAGG CCCTCGTGAA TGTAACAGCT TCCTCAGGCA TGCCAGAGAA
    ACCCCTGATT CCTACCGAGA CTCTCCTCAT AGTGAAAGGT ATGTGTCAGC CATGACCACC
    CCGGCTCGTA TGTCACCTGT AGATTTCCAC ACGCCAAGCT CCCCCAAATC GCCCCCTTCG
    GAAATGTCTC CACCCGTGTC CAGCATGACG GTGTCCATGC CTTCCATGGC GGTCAGCCCC
    TTCATGGAAG AAGAGAGACC TCTACTTCTC GTGACACCAC CAAGGCTGCG GGAGAAGAAG
    TTTGACCATC ACCCTCAGCA GTTCAGCTCC TTCCACCACA ACCCCGCGCA TGACAGTAAC
    AGCCTCCCTG CTAGCCCCTT GAGGATAGTG GAGGATGAGG AGTATGAAAC GACCCAAGAG
    TACGAGCCAG CCCAAGAGCC TGTTAAGAAA CTCGCCAATA GCCGGCGGGC CAAAAGAACC
    AAGCCCAATG GCCACATTGC TAACAGATTG GAAGTGGACA GCAACACAAG CTCCCAGAGC
    AGTAACTCAG AGAGTGAAAC AGAAGATGAA AGAGTAGGTG AAGATACGCC TTTCCTGGGC
    ATACAGAACC CCCTGGCAGC CAGTCTTGAG GCAACACCTG CCTTCCGCCT GGCTGACAGC
    AGGACTAACC CAGCAGGCCG CTTCTCGACA CAGGAAGAAA TCCAGGCCAG GCTGTCTAGT
    GTAATTGCTA ACCAAGACCC TATTGCTGTA TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu28421
    Clone ID Related Accession (Same CDS sequence) NM_001160001.1 , NM_001160001.3 , NM_001160001.2
    Accession Version NM_001160001.3 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1773bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-20
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform HRG-beta1d
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from GQ983557.1, CN603654.1, EF372273.1, M94165.1, DA805080.1, AC113209.4 and CA429204.1. On Jun 2, 2019 this sequence version replaced NM_001160001.2. Transcript Variant: This variant (HRG-beta1d), which uses the type IV promoter, contains an alternate 5' terminal exon and thus differs in the 5' UTR and 5' coding region, and it also lacks two in-frame exons in the central coding region, compared to variant HRG-beta1. The resulting isoform (HRG-beta1d, also known as IV-beta 1a or type IV fetal A beta 1a) has a distinct N-terminus, lacks an internal segment, and is shorter than isoform HRG-beta1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: GQ983557.1, EF372274.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    ATGGGGAAAG GACGCGCGGG CCGAGTTGGC ACCACAGCCT TGCCTCCCCG ATTGAAAGAG 
    ATGAAAAGCC AGGAATCGGC TGCAGGTTCC AAACTAGTCC TTCGGTGTGA AACCAGTTCT
    GAATACTCCT CTCTCAGATT CAAGTGGTTC AAGAATGGGA ATGAATTGAA TCGAAAAAAC
    AAACCACAAA ATATCAAGAT ACAAAAAAAG CCAGGGAAGT CAGAACTTCG CATTAACAAA
    GCATCACTGG CTGATTCTGG AGAGTATATG TGCAAAGTGA TCAGCAAATT AGGAAATGAC
    AGTGCCTCTG CCAATATCAC CATCGTGGAA TCAAACGCTA CATCTACATC CACCACTGGG
    ACAAGCCATC TTGTAAAATG TGCGGAGAAG GAGAAAACTT TCTGTGTGAA TGGAGGGGAG
    TGCTTCATGG TGAAAGACCT TTCAAACCCC TCGAGATACT TGTGCAAGTG CCCAAATGAG
    TTTACTGGTG ATCGCTGCCA AAACTACGTA ATGGCCAGCT TCTACAAGCA TCTTGGGATT
    GAATTTATGG AGGCGGAGGA GCTGTACCAG AAGAGAGTGC TGACCATAAC CGGCATCTGC
    ATCGCCCTCC TTGTGGTCGG CATCATGTGT GTGGTGGCCT ACTGCAAAAC CAAGAAACAG
    CGGAAAAAGC TGCATGACCG TCTTCGGCAG AGCCTTCGGT CTGAACGAAA CAATATGATG
    AACATTGCCA ATGGGCCTCA CCATCCTAAC CCACCCCCCG AGAATGTCCA GCTGGTGAAT
    CAATACGTAT CTAAAAACGT CATCTCCAGT GAGCATATTG TTGAGAGAGA AGCAGAGACA
    TCCTTTTCCA CCAGTCACTA TACTTCCACA GCCCATCACT CCACTACTGT CACCCAGACT
    CCTAGCCACA GCTGGAGCAA CGGACACACT GAAAGCATCC TTTCCGAAAG CCACTCTGTA
    ATCGTGATGT CATCCGTAGA AAACAGTAGG CACAGCAGCC CAACTGGGGG CCCAAGAGGA
    CGTCTTAATG GCACAGGAGG CCCTCGTGAA TGTAACAGCT TCCTCAGGCA TGCCAGAGAA
    ACCCCTGATT CCTACCGAGA CTCTCCTCAT AGTGAAAGGT ATGTGTCAGC CATGACCACC
    CCGGCTCGTA TGTCACCTGT AGATTTCCAC ACGCCAAGCT CCCCCAAATC GCCCCCTTCG
    GAAATGTCTC CACCCGTGTC CAGCATGACG GTGTCCATGC CTTCCATGGC GGTCAGCCCC
    TTCATGGAAG AAGAGAGACC TCTACTTCTC GTGACACCAC CAAGGCTGCG GGAGAAGAAG
    TTTGACCATC ACCCTCAGCA GTTCAGCTCC TTCCACCACA ACCCCGCGCA TGACAGTAAC
    AGCCTCCCTG CTAGCCCCTT GAGGATAGTG GAGGATGAGG AGTATGAAAC GACCCAAGAG
    TACGAGCCAG CCCAAGAGCC TGTTAAGAAA CTCGCCAATA GCCGGCGGGC CAAAAGAACC
    AAGCCCAATG GCCACATTGC TAACAGATTG GAAGTGGACA GCAACACAAG CTCCCAGAGC
    AGTAACTCAG AGAGTGAAAC AGAAGATGAA AGAGTAGGTG AAGATACGCC TTTCCTGGGC
    ATACAGAACC CCCTGGCAGC CAGTCTTGAG GCAACACCTG CCTTCCGCCT GGCTGACAGC
    AGGACTAACC CAGCAGGCCG CTTCTCGACA CAGGAAGAAA TCCAGGCCAG GCTGTCTAGT
    GTAATTGCTA ACCAAGACCC TATTGCTGTA TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001153473.1
    CDS151..1923
    Translation

    Target ORF information:

    RefSeq Version NM_001160001.3
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta1d, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001160001.3

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    ATGGGGAAAG GACGCGCGGG CCGAGTTGGC ACCACAGCCT TGCCTCCCCG ATTGAAAGAG 
    ATGAAAAGCC AGGAATCGGC TGCAGGTTCC AAACTAGTCC TTCGGTGTGA AACCAGTTCT
    GAATACTCCT CTCTCAGATT CAAGTGGTTC AAGAATGGGA ATGAATTGAA TCGAAAAAAC
    AAACCACAAA ATATCAAGAT ACAAAAAAAG CCAGGGAAGT CAGAACTTCG CATTAACAAA
    GCATCACTGG CTGATTCTGG AGAGTATATG TGCAAAGTGA TCAGCAAATT AGGAAATGAC
    AGTGCCTCTG CCAATATCAC CATCGTGGAA TCAAACGCTA CATCTACATC CACCACTGGG
    ACAAGCCATC TTGTAAAATG TGCGGAGAAG GAGAAAACTT TCTGTGTGAA TGGAGGGGAG
    TGCTTCATGG TGAAAGACCT TTCAAACCCC TCGAGATACT TGTGCAAGTG CCCAAATGAG
    TTTACTGGTG ATCGCTGCCA AAACTACGTA ATGGCCAGCT TCTACAAGCA TCTTGGGATT
    GAATTTATGG AGGCGGAGGA GCTGTACCAG AAGAGAGTGC TGACCATAAC CGGCATCTGC
    ATCGCCCTCC TTGTGGTCGG CATCATGTGT GTGGTGGCCT ACTGCAAAAC CAAGAAACAG
    CGGAAAAAGC TGCATGACCG TCTTCGGCAG AGCCTTCGGT CTGAACGAAA CAATATGATG
    AACATTGCCA ATGGGCCTCA CCATCCTAAC CCACCCCCCG AGAATGTCCA GCTGGTGAAT
    CAATACGTAT CTAAAAACGT CATCTCCAGT GAGCATATTG TTGAGAGAGA AGCAGAGACA
    TCCTTTTCCA CCAGTCACTA TACTTCCACA GCCCATCACT CCACTACTGT CACCCAGACT
    CCTAGCCACA GCTGGAGCAA CGGACACACT GAAAGCATCC TTTCCGAAAG CCACTCTGTA
    ATCGTGATGT CATCCGTAGA AAACAGTAGG CACAGCAGCC CAACTGGGGG CCCAAGAGGA
    CGTCTTAATG GCACAGGAGG CCCTCGTGAA TGTAACAGCT TCCTCAGGCA TGCCAGAGAA
    ACCCCTGATT CCTACCGAGA CTCTCCTCAT AGTGAAAGGT ATGTGTCAGC CATGACCACC
    CCGGCTCGTA TGTCACCTGT AGATTTCCAC ACGCCAAGCT CCCCCAAATC GCCCCCTTCG
    GAAATGTCTC CACCCGTGTC CAGCATGACG GTGTCCATGC CTTCCATGGC GGTCAGCCCC
    TTCATGGAAG AAGAGAGACC TCTACTTCTC GTGACACCAC CAAGGCTGCG GGAGAAGAAG
    TTTGACCATC ACCCTCAGCA GTTCAGCTCC TTCCACCACA ACCCCGCGCA TGACAGTAAC
    AGCCTCCCTG CTAGCCCCTT GAGGATAGTG GAGGATGAGG AGTATGAAAC GACCCAAGAG
    TACGAGCCAG CCCAAGAGCC TGTTAAGAAA CTCGCCAATA GCCGGCGGGC CAAAAGAACC
    AAGCCCAATG GCCACATTGC TAACAGATTG GAAGTGGACA GCAACACAAG CTCCCAGAGC
    AGTAACTCAG AGAGTGAAAC AGAAGATGAA AGAGTAGGTG AAGATACGCC TTTCCTGGGC
    ATACAGAACC CCCTGGCAGC CAGTCTTGAG GCAACACCTG CCTTCCGCCT GGCTGACAGC
    AGGACTAACC CAGCAGGCCG CTTCTCGACA CAGGAAGAAA TCCAGGCCAG GCTGTCTAGT
    GTAATTGCTA ACCAAGACCC TATTGCTGTA TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu28421
    Clone ID Related Accession (Same CDS sequence) NM_001160001.1 , NM_001160001.3 , NM_001160001.2
    Accession Version NM_001160001.2 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1773bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2018-12-22
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform HRG-beta1d
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from GQ983557.1, CN603654.1, EF372273.1, M94165.1, DA805080.1, AC113209.4 and CA429204.1. On Apr 8, 2016 this sequence version replaced NM_001160001.1. Transcript Variant: This variant (HRG-beta1d), which uses the type IV promoter, contains an alternate 5' terminal exon and thus differs in the 5' UTR and 5' coding region, and it also lacks two in-frame exons in the central coding region, compared to variant HRG-beta1. The resulting isoform (HRG-beta1d, also known as IV-beta 1a or type IV fetal A beta 1a) has a distinct N-terminus, lacks an internal segment, and is shorter than isoform HRG-beta1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: GQ983557.1, EF372273.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    ATGGGGAAAG GACGCGCGGG CCGAGTTGGC ACCACAGCCT TGCCTCCCCG ATTGAAAGAG 
    ATGAAAAGCC AGGAATCGGC TGCAGGTTCC AAACTAGTCC TTCGGTGTGA AACCAGTTCT
    GAATACTCCT CTCTCAGATT CAAGTGGTTC AAGAATGGGA ATGAATTGAA TCGAAAAAAC
    AAACCACAAA ATATCAAGAT ACAAAAAAAG CCAGGGAAGT CAGAACTTCG CATTAACAAA
    GCATCACTGG CTGATTCTGG AGAGTATATG TGCAAAGTGA TCAGCAAATT AGGAAATGAC
    AGTGCCTCTG CCAATATCAC CATCGTGGAA TCAAACGCTA CATCTACATC CACCACTGGG
    ACAAGCCATC TTGTAAAATG TGCGGAGAAG GAGAAAACTT TCTGTGTGAA TGGAGGGGAG
    TGCTTCATGG TGAAAGACCT TTCAAACCCC TCGAGATACT TGTGCAAGTG CCCAAATGAG
    TTTACTGGTG ATCGCTGCCA AAACTACGTA ATGGCCAGCT TCTACAAGCA TCTTGGGATT
    GAATTTATGG AGGCGGAGGA GCTGTACCAG AAGAGAGTGC TGACCATAAC CGGCATCTGC
    ATCGCCCTCC TTGTGGTCGG CATCATGTGT GTGGTGGCCT ACTGCAAAAC CAAGAAACAG
    CGGAAAAAGC TGCATGACCG TCTTCGGCAG AGCCTTCGGT CTGAACGAAA CAATATGATG
    AACATTGCCA ATGGGCCTCA CCATCCTAAC CCACCCCCCG AGAATGTCCA GCTGGTGAAT
    CAATACGTAT CTAAAAACGT CATCTCCAGT GAGCATATTG TTGAGAGAGA AGCAGAGACA
    TCCTTTTCCA CCAGTCACTA TACTTCCACA GCCCATCACT CCACTACTGT CACCCAGACT
    CCTAGCCACA GCTGGAGCAA CGGACACACT GAAAGCATCC TTTCCGAAAG CCACTCTGTA
    ATCGTGATGT CATCCGTAGA AAACAGTAGG CACAGCAGCC CAACTGGGGG CCCAAGAGGA
    CGTCTTAATG GCACAGGAGG CCCTCGTGAA TGTAACAGCT TCCTCAGGCA TGCCAGAGAA
    ACCCCTGATT CCTACCGAGA CTCTCCTCAT AGTGAAAGGT ATGTGTCAGC CATGACCACC
    CCGGCTCGTA TGTCACCTGT AGATTTCCAC ACGCCAAGCT CCCCCAAATC GCCCCCTTCG
    GAAATGTCTC CACCCGTGTC CAGCATGACG GTGTCCATGC CTTCCATGGC GGTCAGCCCC
    TTCATGGAAG AAGAGAGACC TCTACTTCTC GTGACACCAC CAAGGCTGCG GGAGAAGAAG
    TTTGACCATC ACCCTCAGCA GTTCAGCTCC TTCCACCACA ACCCCGCGCA TGACAGTAAC
    AGCCTCCCTG CTAGCCCCTT GAGGATAGTG GAGGATGAGG AGTATGAAAC GACCCAAGAG
    TACGAGCCAG CCCAAGAGCC TGTTAAGAAA CTCGCCAATA GCCGGCGGGC CAAAAGAACC
    AAGCCCAATG GCCACATTGC TAACAGATTG GAAGTGGACA GCAACACAAG CTCCCAGAGC
    AGTAACTCAG AGAGTGAAAC AGAAGATGAA AGAGTAGGTG AAGATACGCC TTTCCTGGGC
    ATACAGAACC CCCTGGCAGC CAGTCTTGAG GCAACACCTG CCTTCCGCCT GGCTGACAGC
    AGGACTAACC CAGCAGGCCG CTTCTCGACA CAGGAAGAAA TCCAGGCCAG GCTGTCTAGT
    GTAATTGCTA ACCAAGACCC TATTGCTGTA TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001153473.1
    CDS174..1946
    Translation

    Target ORF information:

    RefSeq Version NM_001160001.2
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta1d, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001160001.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    ATGGGGAAAG GACGCGCGGG CCGAGTTGGC ACCACAGCCT TGCCTCCCCG ATTGAAAGAG 
    ATGAAAAGCC AGGAATCGGC TGCAGGTTCC AAACTAGTCC TTCGGTGTGA AACCAGTTCT
    GAATACTCCT CTCTCAGATT CAAGTGGTTC AAGAATGGGA ATGAATTGAA TCGAAAAAAC
    AAACCACAAA ATATCAAGAT ACAAAAAAAG CCAGGGAAGT CAGAACTTCG CATTAACAAA
    GCATCACTGG CTGATTCTGG AGAGTATATG TGCAAAGTGA TCAGCAAATT AGGAAATGAC
    AGTGCCTCTG CCAATATCAC CATCGTGGAA TCAAACGCTA CATCTACATC CACCACTGGG
    ACAAGCCATC TTGTAAAATG TGCGGAGAAG GAGAAAACTT TCTGTGTGAA TGGAGGGGAG
    TGCTTCATGG TGAAAGACCT TTCAAACCCC TCGAGATACT TGTGCAAGTG CCCAAATGAG
    TTTACTGGTG ATCGCTGCCA AAACTACGTA ATGGCCAGCT TCTACAAGCA TCTTGGGATT
    GAATTTATGG AGGCGGAGGA GCTGTACCAG AAGAGAGTGC TGACCATAAC CGGCATCTGC
    ATCGCCCTCC TTGTGGTCGG CATCATGTGT GTGGTGGCCT ACTGCAAAAC CAAGAAACAG
    CGGAAAAAGC TGCATGACCG TCTTCGGCAG AGCCTTCGGT CTGAACGAAA CAATATGATG
    AACATTGCCA ATGGGCCTCA CCATCCTAAC CCACCCCCCG AGAATGTCCA GCTGGTGAAT
    CAATACGTAT CTAAAAACGT CATCTCCAGT GAGCATATTG TTGAGAGAGA AGCAGAGACA
    TCCTTTTCCA CCAGTCACTA TACTTCCACA GCCCATCACT CCACTACTGT CACCCAGACT
    CCTAGCCACA GCTGGAGCAA CGGACACACT GAAAGCATCC TTTCCGAAAG CCACTCTGTA
    ATCGTGATGT CATCCGTAGA AAACAGTAGG CACAGCAGCC CAACTGGGGG CCCAAGAGGA
    CGTCTTAATG GCACAGGAGG CCCTCGTGAA TGTAACAGCT TCCTCAGGCA TGCCAGAGAA
    ACCCCTGATT CCTACCGAGA CTCTCCTCAT AGTGAAAGGT ATGTGTCAGC CATGACCACC
    CCGGCTCGTA TGTCACCTGT AGATTTCCAC ACGCCAAGCT CCCCCAAATC GCCCCCTTCG
    GAAATGTCTC CACCCGTGTC CAGCATGACG GTGTCCATGC CTTCCATGGC GGTCAGCCCC
    TTCATGGAAG AAGAGAGACC TCTACTTCTC GTGACACCAC CAAGGCTGCG GGAGAAGAAG
    TTTGACCATC ACCCTCAGCA GTTCAGCTCC TTCCACCACA ACCCCGCGCA TGACAGTAAC
    AGCCTCCCTG CTAGCCCCTT GAGGATAGTG GAGGATGAGG AGTATGAAAC GACCCAAGAG
    TACGAGCCAG CCCAAGAGCC TGTTAAGAAA CTCGCCAATA GCCGGCGGGC CAAAAGAACC
    AAGCCCAATG GCCACATTGC TAACAGATTG GAAGTGGACA GCAACACAAG CTCCCAGAGC
    AGTAACTCAG AGAGTGAAAC AGAAGATGAA AGAGTAGGTG AAGATACGCC TTTCCTGGGC
    ATACAGAACC CCCTGGCAGC CAGTCTTGAG GCAACACCTG CCTTCCGCCT GGCTGACAGC
    AGGACTAACC CAGCAGGCCG CTTCTCGACA CAGGAAGAAA TCCAGGCCAG GCTGTCTAGT
    GTAATTGCTA ACCAAGACCC TATTGCTGTA TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu28423
    Clone ID Related Accession (Same CDS sequence) NM_013957.5 , NM_013957.4 , NM_013957.3
    Accession Version NM_013957.5 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1914bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-20
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform HRG-beta2
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK298132.1, AK097005.1, BC006492.2, AK290730.1, M94165.1, DA805080.1, AC113209.4 and CA429204.1. On Jun 2, 2019 this sequence version replaced NM_013957.4. Transcript Variant: This variant (HRG-beta2), which uses the type I promoter, lacks an alternate in-frame exon in the central coding region, compared to variant HRG-beta1, resulting in an isoform (HRG-beta2) that is shorter than isoform HRG-beta1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK290730.1, M94167.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTGCCCAA ATGAGTTTAC TGGTGATCGC
    TGCCAAAACT ACGTAATGGC CAGCTTCTAC AAGGCGGAGG AGCTGTACCA GAAGAGAGTG
    CTGACCATAA CCGGCATCTG CATCGCCCTC CTTGTGGTCG GCATCATGTG TGTGGTGGCC
    TACTGCAAAA CCAAGAAACA GCGGAAAAAG CTGCATGACC GTCTTCGGCA GAGCCTTCGG
    TCTGAACGAA ACAATATGAT GAACATTGCC AATGGGCCTC ACCATCCTAA CCCACCCCCC
    GAGAATGTCC AGCTGGTGAA TCAATACGTA TCTAAAAACG TCATCTCCAG TGAGCATATT
    GTTGAGAGAG AAGCAGAGAC ATCCTTTTCC ACCAGTCACT ATACTTCCAC AGCCCATCAC
    TCCACTACTG TCACCCAGAC TCCTAGCCAC AGCTGGAGCA ACGGACACAC TGAAAGCATC
    CTTTCCGAAA GCCACTCTGT AATCGTGATG TCATCCGTAG AAAACAGTAG GCACAGCAGC
    CCAACTGGGG GCCCAAGAGG ACGTCTTAAT GGCACAGGAG GCCCTCGTGA ATGTAACAGC
    TTCCTCAGGC ATGCCAGAGA AACCCCTGAT TCCTACCGAG ACTCTCCTCA TAGTGAAAGG
    TATGTGTCAG CCATGACCAC CCCGGCTCGT ATGTCACCTG TAGATTTCCA CACGCCAAGC
    TCCCCCAAAT CGCCCCCTTC GGAAATGTCT CCACCCGTGT CCAGCATGAC GGTGTCCATG
    CCTTCCATGG CGGTCAGCCC CTTCATGGAA GAAGAGAGAC CTCTACTTCT CGTGACACCA
    CCAAGGCTGC GGGAGAAGAA GTTTGACCAT CACCCTCAGC AGTTCAGCTC CTTCCACCAC
    AACCCCGCGC ATGACAGTAA CAGCCTCCCT GCTAGCCCCT TGAGGATAGT GGAGGATGAG
    GAGTATGAAA CGACCCAAGA GTACGAGCCA GCCCAAGAGC CTGTTAAGAA ACTCGCCAAT
    AGCCGGCGGG CCAAAAGAAC CAAGCCCAAT GGCCACATTG CTAACAGATT GGAAGTGGAC
    AGCAACACAA GCTCCCAGAG CAGTAACTCA GAGAGTGAAA CAGAAGATGA AAGAGTAGGT
    GAAGATACGC CTTTCCTGGG CATACAGAAC CCCCTGGCAG CCAGTCTTGA GGCAACACCT
    GCCTTCCGCC TGGCTGACAG CAGGACTAAC CCAGCAGGCC GCTTCTCGAC ACAGGAAGAA
    ATCCAGGCCA GGCTGTCTAG TGTAATTGCT AACCAAGACC CTATTGCTGT ATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_039251.2
    CDS417..2330
    Translation

    Target ORF information:

    RefSeq Version NM_013957.5
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta2, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_013957.5

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTGCCCAA ATGAGTTTAC TGGTGATCGC
    TGCCAAAACT ACGTAATGGC CAGCTTCTAC AAGGCGGAGG AGCTGTACCA GAAGAGAGTG
    CTGACCATAA CCGGCATCTG CATCGCCCTC CTTGTGGTCG GCATCATGTG TGTGGTGGCC
    TACTGCAAAA CCAAGAAACA GCGGAAAAAG CTGCATGACC GTCTTCGGCA GAGCCTTCGG
    TCTGAACGAA ACAATATGAT GAACATTGCC AATGGGCCTC ACCATCCTAA CCCACCCCCC
    GAGAATGTCC AGCTGGTGAA TCAATACGTA TCTAAAAACG TCATCTCCAG TGAGCATATT
    GTTGAGAGAG AAGCAGAGAC ATCCTTTTCC ACCAGTCACT ATACTTCCAC AGCCCATCAC
    TCCACTACTG TCACCCAGAC TCCTAGCCAC AGCTGGAGCA ACGGACACAC TGAAAGCATC
    CTTTCCGAAA GCCACTCTGT AATCGTGATG TCATCCGTAG AAAACAGTAG GCACAGCAGC
    CCAACTGGGG GCCCAAGAGG ACGTCTTAAT GGCACAGGAG GCCCTCGTGA ATGTAACAGC
    TTCCTCAGGC ATGCCAGAGA AACCCCTGAT TCCTACCGAG ACTCTCCTCA TAGTGAAAGG
    TATGTGTCAG CCATGACCAC CCCGGCTCGT ATGTCACCTG TAGATTTCCA CACGCCAAGC
    TCCCCCAAAT CGCCCCCTTC GGAAATGTCT CCACCCGTGT CCAGCATGAC GGTGTCCATG
    CCTTCCATGG CGGTCAGCCC CTTCATGGAA GAAGAGAGAC CTCTACTTCT CGTGACACCA
    CCAAGGCTGC GGGAGAAGAA GTTTGACCAT CACCCTCAGC AGTTCAGCTC CTTCCACCAC
    AACCCCGCGC ATGACAGTAA CAGCCTCCCT GCTAGCCCCT TGAGGATAGT GGAGGATGAG
    GAGTATGAAA CGACCCAAGA GTACGAGCCA GCCCAAGAGC CTGTTAAGAA ACTCGCCAAT
    AGCCGGCGGG CCAAAAGAAC CAAGCCCAAT GGCCACATTG CTAACAGATT GGAAGTGGAC
    AGCAACACAA GCTCCCAGAG CAGTAACTCA GAGAGTGAAA CAGAAGATGA AAGAGTAGGT
    GAAGATACGC CTTTCCTGGG CATACAGAAC CCCCTGGCAG CCAGTCTTGA GGCAACACCT
    GCCTTCCGCC TGGCTGACAG CAGGACTAAC CCAGCAGGCC GCTTCTCGAC ACAGGAAGAA
    ATCCAGGCCA GGCTGTCTAG TGTAATTGCT AACCAAGACC CTATTGCTGT ATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu28423
    Clone ID Related Accession (Same CDS sequence) NM_013957.5 , NM_013957.4 , NM_013957.3
    Accession Version NM_013957.4 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1914bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2018-12-22
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform HRG-beta2
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK298132.1, AK097005.1, BC006492.2, AK290730.1, M94165.1, DA805080.1, AC113209.4 and CA429204.1. On Apr 8, 2016 this sequence version replaced NM_013957.3. Transcript Variant: This variant (HRG-beta2), which uses the type I promoter, lacks an alternate in-frame exon in the central coding region, compared to variant HRG-beta1, resulting in an isoform (HRG-beta2) that is shorter than isoform HRG-beta1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M94167.1, AK290730.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTGCCCAA ATGAGTTTAC TGGTGATCGC
    TGCCAAAACT ACGTAATGGC CAGCTTCTAC AAGGCGGAGG AGCTGTACCA GAAGAGAGTG
    CTGACCATAA CCGGCATCTG CATCGCCCTC CTTGTGGTCG GCATCATGTG TGTGGTGGCC
    TACTGCAAAA CCAAGAAACA GCGGAAAAAG CTGCATGACC GTCTTCGGCA GAGCCTTCGG
    TCTGAACGAA ACAATATGAT GAACATTGCC AATGGGCCTC ACCATCCTAA CCCACCCCCC
    GAGAATGTCC AGCTGGTGAA TCAATACGTA TCTAAAAACG TCATCTCCAG TGAGCATATT
    GTTGAGAGAG AAGCAGAGAC ATCCTTTTCC ACCAGTCACT ATACTTCCAC AGCCCATCAC
    TCCACTACTG TCACCCAGAC TCCTAGCCAC AGCTGGAGCA ACGGACACAC TGAAAGCATC
    CTTTCCGAAA GCCACTCTGT AATCGTGATG TCATCCGTAG AAAACAGTAG GCACAGCAGC
    CCAACTGGGG GCCCAAGAGG ACGTCTTAAT GGCACAGGAG GCCCTCGTGA ATGTAACAGC
    TTCCTCAGGC ATGCCAGAGA AACCCCTGAT TCCTACCGAG ACTCTCCTCA TAGTGAAAGG
    TATGTGTCAG CCATGACCAC CCCGGCTCGT ATGTCACCTG TAGATTTCCA CACGCCAAGC
    TCCCCCAAAT CGCCCCCTTC GGAAATGTCT CCACCCGTGT CCAGCATGAC GGTGTCCATG
    CCTTCCATGG CGGTCAGCCC CTTCATGGAA GAAGAGAGAC CTCTACTTCT CGTGACACCA
    CCAAGGCTGC GGGAGAAGAA GTTTGACCAT CACCCTCAGC AGTTCAGCTC CTTCCACCAC
    AACCCCGCGC ATGACAGTAA CAGCCTCCCT GCTAGCCCCT TGAGGATAGT GGAGGATGAG
    GAGTATGAAA CGACCCAAGA GTACGAGCCA GCCCAAGAGC CTGTTAAGAA ACTCGCCAAT
    AGCCGGCGGG CCAAAAGAAC CAAGCCCAAT GGCCACATTG CTAACAGATT GGAAGTGGAC
    AGCAACACAA GCTCCCAGAG CAGTAACTCA GAGAGTGAAA CAGAAGATGA AAGAGTAGGT
    GAAGATACGC CTTTCCTGGG CATACAGAAC CCCCTGGCAG CCAGTCTTGA GGCAACACCT
    GCCTTCCGCC TGGCTGACAG CAGGACTAAC CCAGCAGGCC GCTTCTCGAC ACAGGAAGAA
    ATCCAGGCCA GGCTGTCTAG TGTAATTGCT AACCAAGACC CTATTGCTGT ATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_039251.2
    CDS518..2431
    Translation

    Target ORF information:

    RefSeq Version NM_013957.4
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta2, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_013957.4

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTGCCCAA ATGAGTTTAC TGGTGATCGC
    TGCCAAAACT ACGTAATGGC CAGCTTCTAC AAGGCGGAGG AGCTGTACCA GAAGAGAGTG
    CTGACCATAA CCGGCATCTG CATCGCCCTC CTTGTGGTCG GCATCATGTG TGTGGTGGCC
    TACTGCAAAA CCAAGAAACA GCGGAAAAAG CTGCATGACC GTCTTCGGCA GAGCCTTCGG
    TCTGAACGAA ACAATATGAT GAACATTGCC AATGGGCCTC ACCATCCTAA CCCACCCCCC
    GAGAATGTCC AGCTGGTGAA TCAATACGTA TCTAAAAACG TCATCTCCAG TGAGCATATT
    GTTGAGAGAG AAGCAGAGAC ATCCTTTTCC ACCAGTCACT ATACTTCCAC AGCCCATCAC
    TCCACTACTG TCACCCAGAC TCCTAGCCAC AGCTGGAGCA ACGGACACAC TGAAAGCATC
    CTTTCCGAAA GCCACTCTGT AATCGTGATG TCATCCGTAG AAAACAGTAG GCACAGCAGC
    CCAACTGGGG GCCCAAGAGG ACGTCTTAAT GGCACAGGAG GCCCTCGTGA ATGTAACAGC
    TTCCTCAGGC ATGCCAGAGA AACCCCTGAT TCCTACCGAG ACTCTCCTCA TAGTGAAAGG
    TATGTGTCAG CCATGACCAC CCCGGCTCGT ATGTCACCTG TAGATTTCCA CACGCCAAGC
    TCCCCCAAAT CGCCCCCTTC GGAAATGTCT CCACCCGTGT CCAGCATGAC GGTGTCCATG
    CCTTCCATGG CGGTCAGCCC CTTCATGGAA GAAGAGAGAC CTCTACTTCT CGTGACACCA
    CCAAGGCTGC GGGAGAAGAA GTTTGACCAT CACCCTCAGC AGTTCAGCTC CTTCCACCAC
    AACCCCGCGC ATGACAGTAA CAGCCTCCCT GCTAGCCCCT TGAGGATAGT GGAGGATGAG
    GAGTATGAAA CGACCCAAGA GTACGAGCCA GCCCAAGAGC CTGTTAAGAA ACTCGCCAAT
    AGCCGGCGGG CCAAAAGAAC CAAGCCCAAT GGCCACATTG CTAACAGATT GGAAGTGGAC
    AGCAACACAA GCTCCCAGAG CAGTAACTCA GAGAGTGAAA CAGAAGATGA AAGAGTAGGT
    GAAGATACGC CTTTCCTGGG CATACAGAAC CCCCTGGCAG CCAGTCTTGA GGCAACACCT
    GCCTTCCGCC TGGCTGACAG CAGGACTAAC CCAGCAGGCC GCTTCTCGAC ACAGGAAGAA
    ATCCAGGCCA GGCTGTCTAG TGTAATTGCT AACCAAGACC CTATTGCTGT ATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu28423
    Clone ID Related Accession (Same CDS sequence) NM_013957.5 , NM_013957.4 , NM_013957.3
    Accession Version NM_013957.3 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1914bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2015-03-14
    Organism Homo sapiens(Human)
    Product pro-neuregulin-1, membrane-bound isoform isoform HRG-beta2
    Comment

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTGCCCAA ATGAGTTTAC TGGTGATCGC
    TGCCAAAACT ACGTAATGGC CAGCTTCTAC AAGGCGGAGG AGCTGTACCA GAAGAGAGTG
    CTGACCATAA CCGGCATCTG CATCGCCCTC CTTGTGGTCG GCATCATGTG TGTGGTGGCC
    TACTGCAAAA CCAAGAAACA GCGGAAAAAG CTGCATGACC GTCTTCGGCA GAGCCTTCGG
    TCTGAACGAA ACAATATGAT GAACATTGCC AATGGGCCTC ACCATCCTAA CCCACCCCCC
    GAGAATGTCC AGCTGGTGAA TCAATACGTA TCTAAAAACG TCATCTCCAG TGAGCATATT
    GTTGAGAGAG AAGCAGAGAC ATCCTTTTCC ACCAGTCACT ATACTTCCAC AGCCCATCAC
    TCCACTACTG TCACCCAGAC TCCTAGCCAC AGCTGGAGCA ACGGACACAC TGAAAGCATC
    CTTTCCGAAA GCCACTCTGT AATCGTGATG TCATCCGTAG AAAACAGTAG GCACAGCAGC
    CCAACTGGGG GCCCAAGAGG ACGTCTTAAT GGCACAGGAG GCCCTCGTGA ATGTAACAGC
    TTCCTCAGGC ATGCCAGAGA AACCCCTGAT TCCTACCGAG ACTCTCCTCA TAGTGAAAGG
    TATGTGTCAG CCATGACCAC CCCGGCTCGT ATGTCACCTG TAGATTTCCA CACGCCAAGC
    TCCCCCAAAT CGCCCCCTTC GGAAATGTCT CCACCCGTGT CCAGCATGAC GGTGTCCATG
    CCTTCCATGG CGGTCAGCCC CTTCATGGAA GAAGAGAGAC CTCTACTTCT CGTGACACCA
    CCAAGGCTGC GGGAGAAGAA GTTTGACCAT CACCCTCAGC AGTTCAGCTC CTTCCACCAC
    AACCCCGCGC ATGACAGTAA CAGCCTCCCT GCTAGCCCCT TGAGGATAGT GGAGGATGAG
    GAGTATGAAA CGACCCAAGA GTACGAGCCA GCCCAAGAGC CTGTTAAGAA ACTCGCCAAT
    AGCCGGCGGG CCAAAAGAAC CAAGCCCAAT GGCCACATTG CTAACAGATT GGAAGTGGAC
    AGCAACACAA GCTCCCAGAG CAGTAACTCA GAGAGTGAAA CAGAAGATGA AAGAGTAGGT
    GAAGATACGC CTTTCCTGGG CATACAGAAC CCCCTGGCAG CCAGTCTTGA GGCAACACCT
    GCCTTCCGCC TGGCTGACAG CAGGACTAAC CCAGCAGGCC GCTTCTCGAC ACAGGAAGAA
    ATCCAGGCCA GGCTGTCTAG TGTAATTGCT AACCAAGACC CTATTGCTGT ATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_039251.2
    Translation

    Target ORF information:

    RefSeq Version NM_013957.3
    Organism Homo sapiens(Human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta2, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_013957.3

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTGCCCAA ATGAGTTTAC TGGTGATCGC
    TGCCAAAACT ACGTAATGGC CAGCTTCTAC AAGGCGGAGG AGCTGTACCA GAAGAGAGTG
    CTGACCATAA CCGGCATCTG CATCGCCCTC CTTGTGGTCG GCATCATGTG TGTGGTGGCC
    TACTGCAAAA CCAAGAAACA GCGGAAAAAG CTGCATGACC GTCTTCGGCA GAGCCTTCGG
    TCTGAACGAA ACAATATGAT GAACATTGCC AATGGGCCTC ACCATCCTAA CCCACCCCCC
    GAGAATGTCC AGCTGGTGAA TCAATACGTA TCTAAAAACG TCATCTCCAG TGAGCATATT
    GTTGAGAGAG AAGCAGAGAC ATCCTTTTCC ACCAGTCACT ATACTTCCAC AGCCCATCAC
    TCCACTACTG TCACCCAGAC TCCTAGCCAC AGCTGGAGCA ACGGACACAC TGAAAGCATC
    CTTTCCGAAA GCCACTCTGT AATCGTGATG TCATCCGTAG AAAACAGTAG GCACAGCAGC
    CCAACTGGGG GCCCAAGAGG ACGTCTTAAT GGCACAGGAG GCCCTCGTGA ATGTAACAGC
    TTCCTCAGGC ATGCCAGAGA AACCCCTGAT TCCTACCGAG ACTCTCCTCA TAGTGAAAGG
    TATGTGTCAG CCATGACCAC CCCGGCTCGT ATGTCACCTG TAGATTTCCA CACGCCAAGC
    TCCCCCAAAT CGCCCCCTTC GGAAATGTCT CCACCCGTGT CCAGCATGAC GGTGTCCATG
    CCTTCCATGG CGGTCAGCCC CTTCATGGAA GAAGAGAGAC CTCTACTTCT CGTGACACCA
    CCAAGGCTGC GGGAGAAGAA GTTTGACCAT CACCCTCAGC AGTTCAGCTC CTTCCACCAC
    AACCCCGCGC ATGACAGTAA CAGCCTCCCT GCTAGCCCCT TGAGGATAGT GGAGGATGAG
    GAGTATGAAA CGACCCAAGA GTACGAGCCA GCCCAAGAGC CTGTTAAGAA ACTCGCCAAT
    AGCCGGCGGG CCAAAAGAAC CAAGCCCAAT GGCCACATTG CTAACAGATT GGAAGTGGAC
    AGCAACACAA GCTCCCAGAG CAGTAACTCA GAGAGTGAAA CAGAAGATGA AAGAGTAGGT
    GAAGATACGC CTTTCCTGGG CATACAGAAC CCCCTGGCAG CCAGTCTTGA GGCAACACCT
    GCCTTCCGCC TGGCTGACAG CAGGACTAAC CCAGCAGGCC GCTTCTCGAC ACAGGAAGAA
    ATCCAGGCCA GGCTGTCTAG TGTAATTGCT AACCAAGACC CTATTGCTGT ATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu28437
    Clone ID Related Accession (Same CDS sequence) NM_013964.4 , NM_013964.3 , NM_013964.5
    Accession Version NM_013964.4 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1923bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-02-24
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform HRG-alpha proprotein
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK298132.1, AK097005.1, BC006492.2, M94165.1, DA805080.1, AC113209.4 and CA429204.1. On Apr 8, 2016 this sequence version replaced NM_013964.3. Transcript Variant: This variant (HRG-alpha), which uses the type I promoter, lacks two in-frame exons but contains a different in-frame exon in the central coding region, compared to variant HRG-beta1. The resulting isoform (HRG-alpha, also known as erbB2 or gp30/alpha 1) contains an alternate internal segment and is shorter than isoform HRG-beta1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M94165.1, S68256.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTGCCAAC CTGGATTCAC TGGAGCAAGA
    TGTACTGAGA ATGTGCCCAT GAAAGTCCAA AACCAAGAAA AGGCGGAGGA GCTGTACCAG
    AAGAGAGTGC TGACCATAAC CGGCATCTGC ATCGCCCTCC TTGTGGTCGG CATCATGTGT
    GTGGTGGCCT ACTGCAAAAC CAAGAAACAG CGGAAAAAGC TGCATGACCG TCTTCGGCAG
    AGCCTTCGGT CTGAACGAAA CAATATGATG AACATTGCCA ATGGGCCTCA CCATCCTAAC
    CCACCCCCCG AGAATGTCCA GCTGGTGAAT CAATACGTAT CTAAAAACGT CATCTCCAGT
    GAGCATATTG TTGAGAGAGA AGCAGAGACA TCCTTTTCCA CCAGTCACTA TACTTCCACA
    GCCCATCACT CCACTACTGT CACCCAGACT CCTAGCCACA GCTGGAGCAA CGGACACACT
    GAAAGCATCC TTTCCGAAAG CCACTCTGTA ATCGTGATGT CATCCGTAGA AAACAGTAGG
    CACAGCAGCC CAACTGGGGG CCCAAGAGGA CGTCTTAATG GCACAGGAGG CCCTCGTGAA
    TGTAACAGCT TCCTCAGGCA TGCCAGAGAA ACCCCTGATT CCTACCGAGA CTCTCCTCAT
    AGTGAAAGGT ATGTGTCAGC CATGACCACC CCGGCTCGTA TGTCACCTGT AGATTTCCAC
    ACGCCAAGCT CCCCCAAATC GCCCCCTTCG GAAATGTCTC CACCCGTGTC CAGCATGACG
    GTGTCCATGC CTTCCATGGC GGTCAGCCCC TTCATGGAAG AAGAGAGACC TCTACTTCTC
    GTGACACCAC CAAGGCTGCG GGAGAAGAAG TTTGACCATC ACCCTCAGCA GTTCAGCTCC
    TTCCACCACA ACCCCGCGCA TGACAGTAAC AGCCTCCCTG CTAGCCCCTT GAGGATAGTG
    GAGGATGAGG AGTATGAAAC GACCCAAGAG TACGAGCCAG CCCAAGAGCC TGTTAAGAAA
    CTCGCCAATA GCCGGCGGGC CAAAAGAACC AAGCCCAATG GCCACATTGC TAACAGATTG
    GAAGTGGACA GCAACACAAG CTCCCAGAGC AGTAACTCAG AGAGTGAAAC AGAAGATGAA
    AGAGTAGGTG AAGATACGCC TTTCCTGGGC ATACAGAACC CCCTGGCAGC CAGTCTTGAG
    GCAACACCTG CCTTCCGCCT GGCTGACAGC AGGACTAACC CAGCAGGCCG CTTCTCGACA
    CAGGAAGAAA TCCAGGCCAG GCTGTCTAGT GTAATTGCTA ACCAAGACCC TATTGCTGTA
    TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_039258.1
    CDS518..2440
    Translation

    Target ORF information:

    RefSeq Version NM_013964.4
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-alpha, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_013964.4

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTGCCAAC CTGGATTCAC TGGAGCAAGA
    TGTACTGAGA ATGTGCCCAT GAAAGTCCAA AACCAAGAAA AGGCGGAGGA GCTGTACCAG
    AAGAGAGTGC TGACCATAAC CGGCATCTGC ATCGCCCTCC TTGTGGTCGG CATCATGTGT
    GTGGTGGCCT ACTGCAAAAC CAAGAAACAG CGGAAAAAGC TGCATGACCG TCTTCGGCAG
    AGCCTTCGGT CTGAACGAAA CAATATGATG AACATTGCCA ATGGGCCTCA CCATCCTAAC
    CCACCCCCCG AGAATGTCCA GCTGGTGAAT CAATACGTAT CTAAAAACGT CATCTCCAGT
    GAGCATATTG TTGAGAGAGA AGCAGAGACA TCCTTTTCCA CCAGTCACTA TACTTCCACA
    GCCCATCACT CCACTACTGT CACCCAGACT CCTAGCCACA GCTGGAGCAA CGGACACACT
    GAAAGCATCC TTTCCGAAAG CCACTCTGTA ATCGTGATGT CATCCGTAGA AAACAGTAGG
    CACAGCAGCC CAACTGGGGG CCCAAGAGGA CGTCTTAATG GCACAGGAGG CCCTCGTGAA
    TGTAACAGCT TCCTCAGGCA TGCCAGAGAA ACCCCTGATT CCTACCGAGA CTCTCCTCAT
    AGTGAAAGGT ATGTGTCAGC CATGACCACC CCGGCTCGTA TGTCACCTGT AGATTTCCAC
    ACGCCAAGCT CCCCCAAATC GCCCCCTTCG GAAATGTCTC CACCCGTGTC CAGCATGACG
    GTGTCCATGC CTTCCATGGC GGTCAGCCCC TTCATGGAAG AAGAGAGACC TCTACTTCTC
    GTGACACCAC CAAGGCTGCG GGAGAAGAAG TTTGACCATC ACCCTCAGCA GTTCAGCTCC
    TTCCACCACA ACCCCGCGCA TGACAGTAAC AGCCTCCCTG CTAGCCCCTT GAGGATAGTG
    GAGGATGAGG AGTATGAAAC GACCCAAGAG TACGAGCCAG CCCAAGAGCC TGTTAAGAAA
    CTCGCCAATA GCCGGCGGGC CAAAAGAACC AAGCCCAATG GCCACATTGC TAACAGATTG
    GAAGTGGACA GCAACACAAG CTCCCAGAGC AGTAACTCAG AGAGTGAAAC AGAAGATGAA
    AGAGTAGGTG AAGATACGCC TTTCCTGGGC ATACAGAACC CCCTGGCAGC CAGTCTTGAG
    GCAACACCTG CCTTCCGCCT GGCTGACAGC AGGACTAACC CAGCAGGCCG CTTCTCGACA
    CAGGAAGAAA TCCAGGCCAG GCTGTCTAGT GTAATTGCTA ACCAAGACCC TATTGCTGTA
    TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu28437
    Clone ID Related Accession (Same CDS sequence) NM_013964.4 , NM_013964.3 , NM_013964.5
    Accession Version NM_013964.3 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1923bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2015-03-14
    Organism Homo sapiens(Human)
    Product pro-neuregulin-1, membrane-bound isoform isoform HRG-alpha
    Comment

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTGCCAAC CTGGATTCAC TGGAGCAAGA
    TGTACTGAGA ATGTGCCCAT GAAAGTCCAA AACCAAGAAA AGGCGGAGGA GCTGTACCAG
    AAGAGAGTGC TGACCATAAC CGGCATCTGC ATCGCCCTCC TTGTGGTCGG CATCATGTGT
    GTGGTGGCCT ACTGCAAAAC CAAGAAACAG CGGAAAAAGC TGCATGACCG TCTTCGGCAG
    AGCCTTCGGT CTGAACGAAA CAATATGATG AACATTGCCA ATGGGCCTCA CCATCCTAAC
    CCACCCCCCG AGAATGTCCA GCTGGTGAAT CAATACGTAT CTAAAAACGT CATCTCCAGT
    GAGCATATTG TTGAGAGAGA AGCAGAGACA TCCTTTTCCA CCAGTCACTA TACTTCCACA
    GCCCATCACT CCACTACTGT CACCCAGACT CCTAGCCACA GCTGGAGCAA CGGACACACT
    GAAAGCATCC TTTCCGAAAG CCACTCTGTA ATCGTGATGT CATCCGTAGA AAACAGTAGG
    CACAGCAGCC CAACTGGGGG CCCAAGAGGA CGTCTTAATG GCACAGGAGG CCCTCGTGAA
    TGTAACAGCT TCCTCAGGCA TGCCAGAGAA ACCCCTGATT CCTACCGAGA CTCTCCTCAT
    AGTGAAAGGT ATGTGTCAGC CATGACCACC CCGGCTCGTA TGTCACCTGT AGATTTCCAC
    ACGCCAAGCT CCCCCAAATC GCCCCCTTCG GAAATGTCTC CACCCGTGTC CAGCATGACG
    GTGTCCATGC CTTCCATGGC GGTCAGCCCC TTCATGGAAG AAGAGAGACC TCTACTTCTC
    GTGACACCAC CAAGGCTGCG GGAGAAGAAG TTTGACCATC ACCCTCAGCA GTTCAGCTCC
    TTCCACCACA ACCCCGCGCA TGACAGTAAC AGCCTCCCTG CTAGCCCCTT GAGGATAGTG
    GAGGATGAGG AGTATGAAAC GACCCAAGAG TACGAGCCAG CCCAAGAGCC TGTTAAGAAA
    CTCGCCAATA GCCGGCGGGC CAAAAGAACC AAGCCCAATG GCCACATTGC TAACAGATTG
    GAAGTGGACA GCAACACAAG CTCCCAGAGC AGTAACTCAG AGAGTGAAAC AGAAGATGAA
    AGAGTAGGTG AAGATACGCC TTTCCTGGGC ATACAGAACC CCCTGGCAGC CAGTCTTGAG
    GCAACACCTG CCTTCCGCCT GGCTGACAGC AGGACTAACC CAGCAGGCCG CTTCTCGACA
    CAGGAAGAAA TCCAGGCCAG GCTGTCTAGT GTAATTGCTA ACCAAGACCC TATTGCTGTA
    TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_039258.1
    Translation

    Target ORF information:

    RefSeq Version NM_013964.3
    Organism Homo sapiens(Human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-alpha, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_013964.3

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTGCCAAC CTGGATTCAC TGGAGCAAGA
    TGTACTGAGA ATGTGCCCAT GAAAGTCCAA AACCAAGAAA AGGCGGAGGA GCTGTACCAG
    AAGAGAGTGC TGACCATAAC CGGCATCTGC ATCGCCCTCC TTGTGGTCGG CATCATGTGT
    GTGGTGGCCT ACTGCAAAAC CAAGAAACAG CGGAAAAAGC TGCATGACCG TCTTCGGCAG
    AGCCTTCGGT CTGAACGAAA CAATATGATG AACATTGCCA ATGGGCCTCA CCATCCTAAC
    CCACCCCCCG AGAATGTCCA GCTGGTGAAT CAATACGTAT CTAAAAACGT CATCTCCAGT
    GAGCATATTG TTGAGAGAGA AGCAGAGACA TCCTTTTCCA CCAGTCACTA TACTTCCACA
    GCCCATCACT CCACTACTGT CACCCAGACT CCTAGCCACA GCTGGAGCAA CGGACACACT
    GAAAGCATCC TTTCCGAAAG CCACTCTGTA ATCGTGATGT CATCCGTAGA AAACAGTAGG
    CACAGCAGCC CAACTGGGGG CCCAAGAGGA CGTCTTAATG GCACAGGAGG CCCTCGTGAA
    TGTAACAGCT TCCTCAGGCA TGCCAGAGAA ACCCCTGATT CCTACCGAGA CTCTCCTCAT
    AGTGAAAGGT ATGTGTCAGC CATGACCACC CCGGCTCGTA TGTCACCTGT AGATTTCCAC
    ACGCCAAGCT CCCCCAAATC GCCCCCTTCG GAAATGTCTC CACCCGTGTC CAGCATGACG
    GTGTCCATGC CTTCCATGGC GGTCAGCCCC TTCATGGAAG AAGAGAGACC TCTACTTCTC
    GTGACACCAC CAAGGCTGCG GGAGAAGAAG TTTGACCATC ACCCTCAGCA GTTCAGCTCC
    TTCCACCACA ACCCCGCGCA TGACAGTAAC AGCCTCCCTG CTAGCCCCTT GAGGATAGTG
    GAGGATGAGG AGTATGAAAC GACCCAAGAG TACGAGCCAG CCCAAGAGCC TGTTAAGAAA
    CTCGCCAATA GCCGGCGGGC CAAAAGAACC AAGCCCAATG GCCACATTGC TAACAGATTG
    GAAGTGGACA GCAACACAAG CTCCCAGAGC AGTAACTCAG AGAGTGAAAC AGAAGATGAA
    AGAGTAGGTG AAGATACGCC TTTCCTGGGC ATACAGAACC CCCTGGCAGC CAGTCTTGAG
    GCAACACCTG CCTTCCGCCT GGCTGACAGC AGGACTAACC CAGCAGGCCG CTTCTCGACA
    CAGGAAGAAA TCCAGGCCAG GCTGTCTAGT GTAATTGCTA ACCAAGACCC TATTGCTGTA
    TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu28437
    Clone ID Related Accession (Same CDS sequence) NM_013964.4 , NM_013964.3 , NM_013964.5
    Accession Version NM_013964.5 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1923bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2020-01-03
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform HRG-alpha proprotein
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK298132.1, AK097005.1, BC006492.2, M94165.1, DA805080.1, AC113209.4 and CA429204.1. On Jun 2, 2019 this sequence version replaced NM_013964.4. Transcript Variant: This variant (HRG-alpha), which uses the type I promoter, lacks two in-frame exons but contains a different in-frame exon in the central coding region, compared to variant HRG-beta1. The resulting isoform (HRG-alpha, also known as erbB2 or gp30/alpha 1) contains an alternate internal segment and is shorter than isoform HRG-beta1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M94165.1, S68256.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTGCCAAC CTGGATTCAC TGGAGCAAGA
    TGTACTGAGA ATGTGCCCAT GAAAGTCCAA AACCAAGAAA AGGCGGAGGA GCTGTACCAG
    AAGAGAGTGC TGACCATAAC CGGCATCTGC ATCGCCCTCC TTGTGGTCGG CATCATGTGT
    GTGGTGGCCT ACTGCAAAAC CAAGAAACAG CGGAAAAAGC TGCATGACCG TCTTCGGCAG
    AGCCTTCGGT CTGAACGAAA CAATATGATG AACATTGCCA ATGGGCCTCA CCATCCTAAC
    CCACCCCCCG AGAATGTCCA GCTGGTGAAT CAATACGTAT CTAAAAACGT CATCTCCAGT
    GAGCATATTG TTGAGAGAGA AGCAGAGACA TCCTTTTCCA CCAGTCACTA TACTTCCACA
    GCCCATCACT CCACTACTGT CACCCAGACT CCTAGCCACA GCTGGAGCAA CGGACACACT
    GAAAGCATCC TTTCCGAAAG CCACTCTGTA ATCGTGATGT CATCCGTAGA AAACAGTAGG
    CACAGCAGCC CAACTGGGGG CCCAAGAGGA CGTCTTAATG GCACAGGAGG CCCTCGTGAA
    TGTAACAGCT TCCTCAGGCA TGCCAGAGAA ACCCCTGATT CCTACCGAGA CTCTCCTCAT
    AGTGAAAGGT ATGTGTCAGC CATGACCACC CCGGCTCGTA TGTCACCTGT AGATTTCCAC
    ACGCCAAGCT CCCCCAAATC GCCCCCTTCG GAAATGTCTC CACCCGTGTC CAGCATGACG
    GTGTCCATGC CTTCCATGGC GGTCAGCCCC TTCATGGAAG AAGAGAGACC TCTACTTCTC
    GTGACACCAC CAAGGCTGCG GGAGAAGAAG TTTGACCATC ACCCTCAGCA GTTCAGCTCC
    TTCCACCACA ACCCCGCGCA TGACAGTAAC AGCCTCCCTG CTAGCCCCTT GAGGATAGTG
    GAGGATGAGG AGTATGAAAC GACCCAAGAG TACGAGCCAG CCCAAGAGCC TGTTAAGAAA
    CTCGCCAATA GCCGGCGGGC CAAAAGAACC AAGCCCAATG GCCACATTGC TAACAGATTG
    GAAGTGGACA GCAACACAAG CTCCCAGAGC AGTAACTCAG AGAGTGAAAC AGAAGATGAA
    AGAGTAGGTG AAGATACGCC TTTCCTGGGC ATACAGAACC CCCTGGCAGC CAGTCTTGAG
    GCAACACCTG CCTTCCGCCT GGCTGACAGC AGGACTAACC CAGCAGGCCG CTTCTCGACA
    CAGGAAGAAA TCCAGGCCAG GCTGTCTAGT GTAATTGCTA ACCAAGACCC TATTGCTGTA
    TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_039258.1
    CDS417..2339
    Translation

    Target ORF information:

    RefSeq Version NM_013964.5
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-alpha, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_013964.5

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTGCCAAC CTGGATTCAC TGGAGCAAGA
    TGTACTGAGA ATGTGCCCAT GAAAGTCCAA AACCAAGAAA AGGCGGAGGA GCTGTACCAG
    AAGAGAGTGC TGACCATAAC CGGCATCTGC ATCGCCCTCC TTGTGGTCGG CATCATGTGT
    GTGGTGGCCT ACTGCAAAAC CAAGAAACAG CGGAAAAAGC TGCATGACCG TCTTCGGCAG
    AGCCTTCGGT CTGAACGAAA CAATATGATG AACATTGCCA ATGGGCCTCA CCATCCTAAC
    CCACCCCCCG AGAATGTCCA GCTGGTGAAT CAATACGTAT CTAAAAACGT CATCTCCAGT
    GAGCATATTG TTGAGAGAGA AGCAGAGACA TCCTTTTCCA CCAGTCACTA TACTTCCACA
    GCCCATCACT CCACTACTGT CACCCAGACT CCTAGCCACA GCTGGAGCAA CGGACACACT
    GAAAGCATCC TTTCCGAAAG CCACTCTGTA ATCGTGATGT CATCCGTAGA AAACAGTAGG
    CACAGCAGCC CAACTGGGGG CCCAAGAGGA CGTCTTAATG GCACAGGAGG CCCTCGTGAA
    TGTAACAGCT TCCTCAGGCA TGCCAGAGAA ACCCCTGATT CCTACCGAGA CTCTCCTCAT
    AGTGAAAGGT ATGTGTCAGC CATGACCACC CCGGCTCGTA TGTCACCTGT AGATTTCCAC
    ACGCCAAGCT CCCCCAAATC GCCCCCTTCG GAAATGTCTC CACCCGTGTC CAGCATGACG
    GTGTCCATGC CTTCCATGGC GGTCAGCCCC TTCATGGAAG AAGAGAGACC TCTACTTCTC
    GTGACACCAC CAAGGCTGCG GGAGAAGAAG TTTGACCATC ACCCTCAGCA GTTCAGCTCC
    TTCCACCACA ACCCCGCGCA TGACAGTAAC AGCCTCCCTG CTAGCCCCTT GAGGATAGTG
    GAGGATGAGG AGTATGAAAC GACCCAAGAG TACGAGCCAG CCCAAGAGCC TGTTAAGAAA
    CTCGCCAATA GCCGGCGGGC CAAAAGAACC AAGCCCAATG GCCACATTGC TAACAGATTG
    GAAGTGGACA GCAACACAAG CTCCCAGAGC AGTAACTCAG AGAGTGAAAC AGAAGATGAA
    AGAGTAGGTG AAGATACGCC TTTCCTGGGC ATACAGAACC CCCTGGCAGC CAGTCTTGAG
    GCAACACCTG CCTTCCGCCT GGCTGACAGC AGGACTAACC CAGCAGGCCG CTTCTCGACA
    CAGGAAGAAA TCCAGGCCAG GCTGTCTAGT GTAATTGCTA ACCAAGACCC TATTGCTGTA
    TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu28439
    Clone ID Related Accession (Same CDS sequence) NM_001159995.1 , NM_001159995.2 , NM_001159995.3
    Accession Version NM_001159995.1 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1824bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2014-06-23
    Organism Homo sapiens(Human)
    Product pro-neuregulin-1, membrane-bound isoform isoform HRG-beta1c
    Comment

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    ATGGGGAAAG GACGCGCGGG CCGAGTTGGC ACCACAGCCT TGCCTCCCCG ATTGAAAGAG 
    ATGAAAAGCC AGGAATCGGC TGCAGGTTCC AAACTAGTCC TTCGGTGTGA AACCAGTTCT
    GAATACTCCT CTCTCAGATT CAAGTGGTTC AAGAATGGGA ATGAATTGAA TCGAAAAAAC
    AAACCACAAA ATATCAAGAT ACAAAAAAAG CCAGGGAAGT CAGAACTTCG CATTAACAAA
    GCATCACTGG CTGATTCTGG AGAGTATATG TGCAAAGTGA TCAGCAAATT AGGAAATGAC
    AGTGCCTCTG CCAATATCAC CATCGTGGAA TCAAACGAGA TCATCACTGG TATGCCAGCC
    TCAACTGAAG GAGCATATGT GTCTTCAGCT ACATCTACAT CCACCACTGG GACAAGCCAT
    CTTGTAAAAT GTGCGGAGAA GGAGAAAACT TTCTGTGTGA ATGGAGGGGA GTGCTTCATG
    GTGAAAGACC TTTCAAACCC CTCGAGATAC TTGTGCAAGT GCCCAAATGA GTTTACTGGT
    GATCGCTGCC AAAACTACGT AATGGCCAGC TTCTACAAGC ATCTTGGGAT TGAATTTATG
    GAGGCGGAGG AGCTGTACCA GAAGAGAGTG CTGACCATAA CCGGCATCTG CATCGCCCTC
    CTTGTGGTCG GCATCATGTG TGTGGTGGCC TACTGCAAAA CCAAGAAACA GCGGAAAAAG
    CTGCATGACC GTCTTCGGCA GAGCCTTCGG TCTGAACGAA ACAATATGAT GAACATTGCC
    AATGGGCCTC ACCATCCTAA CCCACCCCCC GAGAATGTCC AGCTGGTGAA TCAATACGTA
    TCTAAAAACG TCATCTCCAG TGAGCATATT GTTGAGAGAG AAGCAGAGAC ATCCTTTTCC
    ACCAGTCACT ATACTTCCAC AGCCCATCAC TCCACTACTG TCACCCAGAC TCCTAGCCAC
    AGCTGGAGCA ACGGACACAC TGAAAGCATC CTTTCCGAAA GCCACTCTGT AATCGTGATG
    TCATCCGTAG AAAACAGTAG GCACAGCAGC CCAACTGGGG GCCCAAGAGG ACGTCTTAAT
    GGCACAGGAG GCCCTCGTGA ATGTAACAGC TTCCTCAGGC ATGCCAGAGA AACCCCTGAT
    TCCTACCGAG ACTCTCCTCA TAGTGAAAGG TATGTGTCAG CCATGACCAC CCCGGCTCGT
    ATGTCACCTG TAGATTTCCA CACGCCAAGC TCCCCCAAAT CGCCCCCTTC GGAAATGTCT
    CCACCCGTGT CCAGCATGAC GGTGTCCATG CCTTCCATGG CGGTCAGCCC CTTCATGGAA
    GAAGAGAGAC CTCTACTTCT CGTGACACCA CCAAGGCTGC GGGAGAAGAA GTTTGACCAT
    CACCCTCAGC AGTTCAGCTC CTTCCACCAC AACCCCGCGC ATGACAGTAA CAGCCTCCCT
    GCTAGCCCCT TGAGGATAGT GGAGGATGAG GAGTATGAAA CGACCCAAGA GTACGAGCCA
    GCCCAAGAGC CTGTTAAGAA ACTCGCCAAT AGCCGGCGGG CCAAAAGAAC CAAGCCCAAT
    GGCCACATTG CTAACAGATT GGAAGTGGAC AGCAACACAA GCTCCCAGAG CAGTAACTCA
    GAGAGTGAAA CAGAAGATGA AAGAGTAGGT GAAGATACGC CTTTCCTGGG CATACAGAAC
    CCCCTGGCAG CCAGTCTTGA GGCAACACCT GCCTTCCGCC TGGCTGACAG CAGGACTAAC
    CCAGCAGGCC GCTTCTCGAC ACAGGAAGAA ATCCAGGCCA GGCTGTCTAG TGTAATTGCT
    AACCAAGACC CTATTGCTGT ATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001153467.1
    Translation

    Target ORF information:

    RefSeq Version NM_001159995.1
    Organism Homo sapiens(Human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta1c, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001159995.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    ATGGGGAAAG GACGCGCGGG CCGAGTTGGC ACCACAGCCT TGCCTCCCCG ATTGAAAGAG 
    ATGAAAAGCC AGGAATCGGC TGCAGGTTCC AAACTAGTCC TTCGGTGTGA AACCAGTTCT
    GAATACTCCT CTCTCAGATT CAAGTGGTTC AAGAATGGGA ATGAATTGAA TCGAAAAAAC
    AAACCACAAA ATATCAAGAT ACAAAAAAAG CCAGGGAAGT CAGAACTTCG CATTAACAAA
    GCATCACTGG CTGATTCTGG AGAGTATATG TGCAAAGTGA TCAGCAAATT AGGAAATGAC
    AGTGCCTCTG CCAATATCAC CATCGTGGAA TCAAACGAGA TCATCACTGG TATGCCAGCC
    TCAACTGAAG GAGCATATGT GTCTTCAGCT ACATCTACAT CCACCACTGG GACAAGCCAT
    CTTGTAAAAT GTGCGGAGAA GGAGAAAACT TTCTGTGTGA ATGGAGGGGA GTGCTTCATG
    GTGAAAGACC TTTCAAACCC CTCGAGATAC TTGTGCAAGT GCCCAAATGA GTTTACTGGT
    GATCGCTGCC AAAACTACGT AATGGCCAGC TTCTACAAGC ATCTTGGGAT TGAATTTATG
    GAGGCGGAGG AGCTGTACCA GAAGAGAGTG CTGACCATAA CCGGCATCTG CATCGCCCTC
    CTTGTGGTCG GCATCATGTG TGTGGTGGCC TACTGCAAAA CCAAGAAACA GCGGAAAAAG
    CTGCATGACC GTCTTCGGCA GAGCCTTCGG TCTGAACGAA ACAATATGAT GAACATTGCC
    AATGGGCCTC ACCATCCTAA CCCACCCCCC GAGAATGTCC AGCTGGTGAA TCAATACGTA
    TCTAAAAACG TCATCTCCAG TGAGCATATT GTTGAGAGAG AAGCAGAGAC ATCCTTTTCC
    ACCAGTCACT ATACTTCCAC AGCCCATCAC TCCACTACTG TCACCCAGAC TCCTAGCCAC
    AGCTGGAGCA ACGGACACAC TGAAAGCATC CTTTCCGAAA GCCACTCTGT AATCGTGATG
    TCATCCGTAG AAAACAGTAG GCACAGCAGC CCAACTGGGG GCCCAAGAGG ACGTCTTAAT
    GGCACAGGAG GCCCTCGTGA ATGTAACAGC TTCCTCAGGC ATGCCAGAGA AACCCCTGAT
    TCCTACCGAG ACTCTCCTCA TAGTGAAAGG TATGTGTCAG CCATGACCAC CCCGGCTCGT
    ATGTCACCTG TAGATTTCCA CACGCCAAGC TCCCCCAAAT CGCCCCCTTC GGAAATGTCT
    CCACCCGTGT CCAGCATGAC GGTGTCCATG CCTTCCATGG CGGTCAGCCC CTTCATGGAA
    GAAGAGAGAC CTCTACTTCT CGTGACACCA CCAAGGCTGC GGGAGAAGAA GTTTGACCAT
    CACCCTCAGC AGTTCAGCTC CTTCCACCAC AACCCCGCGC ATGACAGTAA CAGCCTCCCT
    GCTAGCCCCT TGAGGATAGT GGAGGATGAG GAGTATGAAA CGACCCAAGA GTACGAGCCA
    GCCCAAGAGC CTGTTAAGAA ACTCGCCAAT AGCCGGCGGG CCAAAAGAAC CAAGCCCAAT
    GGCCACATTG CTAACAGATT GGAAGTGGAC AGCAACACAA GCTCCCAGAG CAGTAACTCA
    GAGAGTGAAA CAGAAGATGA AAGAGTAGGT GAAGATACGC CTTTCCTGGG CATACAGAAC
    CCCCTGGCAG CCAGTCTTGA GGCAACACCT GCCTTCCGCC TGGCTGACAG CAGGACTAAC
    CCAGCAGGCC GCTTCTCGAC ACAGGAAGAA ATCCAGGCCA GGCTGTCTAG TGTAATTGCT
    AACCAAGACC CTATTGCTGT ATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu28439
    Clone ID Related Accession (Same CDS sequence) NM_001159995.1 , NM_001159995.2 , NM_001159995.3
    Accession Version NM_001159995.2 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1824bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2018-12-22
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform HRG-beta1c
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from GQ983557.1, EF517297.1, M94166.1, DA805080.1, AC113209.4 and CA429204.1. On or before May 6, 2016 this sequence version replaced NM_001322203.1, NM_001159995.1. Transcript Variant: This variant (HRG-beta1c), which uses the type IV promoter, contains an alternate 5' terminal exon and thus differs in the 5' UTR and 5' coding region, and it also lacks an in-frame exon in the central coding region, compared to variant HRG-beta1. The resulting isoform (HRG-beta1c, also known as type IV fetal C beta 1a or fetal b IV-beta 1a) has a distinct N-terminus, lacks an internal segment, and is shorter than isoform HRG-beta1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EF517297.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    ATGGGGAAAG GACGCGCGGG CCGAGTTGGC ACCACAGCCT TGCCTCCCCG ATTGAAAGAG 
    ATGAAAAGCC AGGAATCGGC TGCAGGTTCC AAACTAGTCC TTCGGTGTGA AACCAGTTCT
    GAATACTCCT CTCTCAGATT CAAGTGGTTC AAGAATGGGA ATGAATTGAA TCGAAAAAAC
    AAACCACAAA ATATCAAGAT ACAAAAAAAG CCAGGGAAGT CAGAACTTCG CATTAACAAA
    GCATCACTGG CTGATTCTGG AGAGTATATG TGCAAAGTGA TCAGCAAATT AGGAAATGAC
    AGTGCCTCTG CCAATATCAC CATCGTGGAA TCAAACGAGA TCATCACTGG TATGCCAGCC
    TCAACTGAAG GAGCATATGT GTCTTCAGCT ACATCTACAT CCACCACTGG GACAAGCCAT
    CTTGTAAAAT GTGCGGAGAA GGAGAAAACT TTCTGTGTGA ATGGAGGGGA GTGCTTCATG
    GTGAAAGACC TTTCAAACCC CTCGAGATAC TTGTGCAAGT GCCCAAATGA GTTTACTGGT
    GATCGCTGCC AAAACTACGT AATGGCCAGC TTCTACAAGC ATCTTGGGAT TGAATTTATG
    GAGGCGGAGG AGCTGTACCA GAAGAGAGTG CTGACCATAA CCGGCATCTG CATCGCCCTC
    CTTGTGGTCG GCATCATGTG TGTGGTGGCC TACTGCAAAA CCAAGAAACA GCGGAAAAAG
    CTGCATGACC GTCTTCGGCA GAGCCTTCGG TCTGAACGAA ACAATATGAT GAACATTGCC
    AATGGGCCTC ACCATCCTAA CCCACCCCCC GAGAATGTCC AGCTGGTGAA TCAATACGTA
    TCTAAAAACG TCATCTCCAG TGAGCATATT GTTGAGAGAG AAGCAGAGAC ATCCTTTTCC
    ACCAGTCACT ATACTTCCAC AGCCCATCAC TCCACTACTG TCACCCAGAC TCCTAGCCAC
    AGCTGGAGCA ACGGACACAC TGAAAGCATC CTTTCCGAAA GCCACTCTGT AATCGTGATG
    TCATCCGTAG AAAACAGTAG GCACAGCAGC CCAACTGGGG GCCCAAGAGG ACGTCTTAAT
    GGCACAGGAG GCCCTCGTGA ATGTAACAGC TTCCTCAGGC ATGCCAGAGA AACCCCTGAT
    TCCTACCGAG ACTCTCCTCA TAGTGAAAGG TATGTGTCAG CCATGACCAC CCCGGCTCGT
    ATGTCACCTG TAGATTTCCA CACGCCAAGC TCCCCCAAAT CGCCCCCTTC GGAAATGTCT
    CCACCCGTGT CCAGCATGAC GGTGTCCATG CCTTCCATGG CGGTCAGCCC CTTCATGGAA
    GAAGAGAGAC CTCTACTTCT CGTGACACCA CCAAGGCTGC GGGAGAAGAA GTTTGACCAT
    CACCCTCAGC AGTTCAGCTC CTTCCACCAC AACCCCGCGC ATGACAGTAA CAGCCTCCCT
    GCTAGCCCCT TGAGGATAGT GGAGGATGAG GAGTATGAAA CGACCCAAGA GTACGAGCCA
    GCCCAAGAGC CTGTTAAGAA ACTCGCCAAT AGCCGGCGGG CCAAAAGAAC CAAGCCCAAT
    GGCCACATTG CTAACAGATT GGAAGTGGAC AGCAACACAA GCTCCCAGAG CAGTAACTCA
    GAGAGTGAAA CAGAAGATGA AAGAGTAGGT GAAGATACGC CTTTCCTGGG CATACAGAAC
    CCCCTGGCAG CCAGTCTTGA GGCAACACCT GCCTTCCGCC TGGCTGACAG CAGGACTAAC
    CCAGCAGGCC GCTTCTCGAC ACAGGAAGAA ATCCAGGCCA GGCTGTCTAG TGTAATTGCT
    AACCAAGACC CTATTGCTGT ATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001153467.1
    CDS174..1997
    Translation

    Target ORF information:

    RefSeq Version NM_001159995.2
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta1c, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001159995.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    ATGGGGAAAG GACGCGCGGG CCGAGTTGGC ACCACAGCCT TGCCTCCCCG ATTGAAAGAG 
    ATGAAAAGCC AGGAATCGGC TGCAGGTTCC AAACTAGTCC TTCGGTGTGA AACCAGTTCT
    GAATACTCCT CTCTCAGATT CAAGTGGTTC AAGAATGGGA ATGAATTGAA TCGAAAAAAC
    AAACCACAAA ATATCAAGAT ACAAAAAAAG CCAGGGAAGT CAGAACTTCG CATTAACAAA
    GCATCACTGG CTGATTCTGG AGAGTATATG TGCAAAGTGA TCAGCAAATT AGGAAATGAC
    AGTGCCTCTG CCAATATCAC CATCGTGGAA TCAAACGAGA TCATCACTGG TATGCCAGCC
    TCAACTGAAG GAGCATATGT GTCTTCAGCT ACATCTACAT CCACCACTGG GACAAGCCAT
    CTTGTAAAAT GTGCGGAGAA GGAGAAAACT TTCTGTGTGA ATGGAGGGGA GTGCTTCATG
    GTGAAAGACC TTTCAAACCC CTCGAGATAC TTGTGCAAGT GCCCAAATGA GTTTACTGGT
    GATCGCTGCC AAAACTACGT AATGGCCAGC TTCTACAAGC ATCTTGGGAT TGAATTTATG
    GAGGCGGAGG AGCTGTACCA GAAGAGAGTG CTGACCATAA CCGGCATCTG CATCGCCCTC
    CTTGTGGTCG GCATCATGTG TGTGGTGGCC TACTGCAAAA CCAAGAAACA GCGGAAAAAG
    CTGCATGACC GTCTTCGGCA GAGCCTTCGG TCTGAACGAA ACAATATGAT GAACATTGCC
    AATGGGCCTC ACCATCCTAA CCCACCCCCC GAGAATGTCC AGCTGGTGAA TCAATACGTA
    TCTAAAAACG TCATCTCCAG TGAGCATATT GTTGAGAGAG AAGCAGAGAC ATCCTTTTCC
    ACCAGTCACT ATACTTCCAC AGCCCATCAC TCCACTACTG TCACCCAGAC TCCTAGCCAC
    AGCTGGAGCA ACGGACACAC TGAAAGCATC CTTTCCGAAA GCCACTCTGT AATCGTGATG
    TCATCCGTAG AAAACAGTAG GCACAGCAGC CCAACTGGGG GCCCAAGAGG ACGTCTTAAT
    GGCACAGGAG GCCCTCGTGA ATGTAACAGC TTCCTCAGGC ATGCCAGAGA AACCCCTGAT
    TCCTACCGAG ACTCTCCTCA TAGTGAAAGG TATGTGTCAG CCATGACCAC CCCGGCTCGT
    ATGTCACCTG TAGATTTCCA CACGCCAAGC TCCCCCAAAT CGCCCCCTTC GGAAATGTCT
    CCACCCGTGT CCAGCATGAC GGTGTCCATG CCTTCCATGG CGGTCAGCCC CTTCATGGAA
    GAAGAGAGAC CTCTACTTCT CGTGACACCA CCAAGGCTGC GGGAGAAGAA GTTTGACCAT
    CACCCTCAGC AGTTCAGCTC CTTCCACCAC AACCCCGCGC ATGACAGTAA CAGCCTCCCT
    GCTAGCCCCT TGAGGATAGT GGAGGATGAG GAGTATGAAA CGACCCAAGA GTACGAGCCA
    GCCCAAGAGC CTGTTAAGAA ACTCGCCAAT AGCCGGCGGG CCAAAAGAAC CAAGCCCAAT
    GGCCACATTG CTAACAGATT GGAAGTGGAC AGCAACACAA GCTCCCAGAG CAGTAACTCA
    GAGAGTGAAA CAGAAGATGA AAGAGTAGGT GAAGATACGC CTTTCCTGGG CATACAGAAC
    CCCCTGGCAG CCAGTCTTGA GGCAACACCT GCCTTCCGCC TGGCTGACAG CAGGACTAAC
    CCAGCAGGCC GCTTCTCGAC ACAGGAAGAA ATCCAGGCCA GGCTGTCTAG TGTAATTGCT
    AACCAAGACC CTATTGCTGT ATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu28439
    Clone ID Related Accession (Same CDS sequence) NM_001159995.1 , NM_001159995.2 , NM_001159995.3
    Accession Version NM_001159995.3 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1824bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-20
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform HRG-beta1c
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from GQ983557.1, EF517297.1, M94166.1, DA805080.1, AC113209.4 and CA429204.1. On Jun 2, 2019 this sequence version replaced NM_001159995.2. Transcript Variant: This variant (HRG-beta1c), which uses the type IV promoter, contains an alternate 5' terminal exon and thus differs in the 5' UTR and 5' coding region, and it also lacks an in-frame exon in the central coding region, compared to variant HRG-beta1. The resulting isoform (HRG-beta1c, also known as type IV fetal C beta 1a or fetal b IV-beta 1a) has a distinct N-terminus, lacks an internal segment, and is shorter than isoform HRG-beta1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EF517297.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    ATGGGGAAAG GACGCGCGGG CCGAGTTGGC ACCACAGCCT TGCCTCCCCG ATTGAAAGAG 
    ATGAAAAGCC AGGAATCGGC TGCAGGTTCC AAACTAGTCC TTCGGTGTGA AACCAGTTCT
    GAATACTCCT CTCTCAGATT CAAGTGGTTC AAGAATGGGA ATGAATTGAA TCGAAAAAAC
    AAACCACAAA ATATCAAGAT ACAAAAAAAG CCAGGGAAGT CAGAACTTCG CATTAACAAA
    GCATCACTGG CTGATTCTGG AGAGTATATG TGCAAAGTGA TCAGCAAATT AGGAAATGAC
    AGTGCCTCTG CCAATATCAC CATCGTGGAA TCAAACGAGA TCATCACTGG TATGCCAGCC
    TCAACTGAAG GAGCATATGT GTCTTCAGCT ACATCTACAT CCACCACTGG GACAAGCCAT
    CTTGTAAAAT GTGCGGAGAA GGAGAAAACT TTCTGTGTGA ATGGAGGGGA GTGCTTCATG
    GTGAAAGACC TTTCAAACCC CTCGAGATAC TTGTGCAAGT GCCCAAATGA GTTTACTGGT
    GATCGCTGCC AAAACTACGT AATGGCCAGC TTCTACAAGC ATCTTGGGAT TGAATTTATG
    GAGGCGGAGG AGCTGTACCA GAAGAGAGTG CTGACCATAA CCGGCATCTG CATCGCCCTC
    CTTGTGGTCG GCATCATGTG TGTGGTGGCC TACTGCAAAA CCAAGAAACA GCGGAAAAAG
    CTGCATGACC GTCTTCGGCA GAGCCTTCGG TCTGAACGAA ACAATATGAT GAACATTGCC
    AATGGGCCTC ACCATCCTAA CCCACCCCCC GAGAATGTCC AGCTGGTGAA TCAATACGTA
    TCTAAAAACG TCATCTCCAG TGAGCATATT GTTGAGAGAG AAGCAGAGAC ATCCTTTTCC
    ACCAGTCACT ATACTTCCAC AGCCCATCAC TCCACTACTG TCACCCAGAC TCCTAGCCAC
    AGCTGGAGCA ACGGACACAC TGAAAGCATC CTTTCCGAAA GCCACTCTGT AATCGTGATG
    TCATCCGTAG AAAACAGTAG GCACAGCAGC CCAACTGGGG GCCCAAGAGG ACGTCTTAAT
    GGCACAGGAG GCCCTCGTGA ATGTAACAGC TTCCTCAGGC ATGCCAGAGA AACCCCTGAT
    TCCTACCGAG ACTCTCCTCA TAGTGAAAGG TATGTGTCAG CCATGACCAC CCCGGCTCGT
    ATGTCACCTG TAGATTTCCA CACGCCAAGC TCCCCCAAAT CGCCCCCTTC GGAAATGTCT
    CCACCCGTGT CCAGCATGAC GGTGTCCATG CCTTCCATGG CGGTCAGCCC CTTCATGGAA
    GAAGAGAGAC CTCTACTTCT CGTGACACCA CCAAGGCTGC GGGAGAAGAA GTTTGACCAT
    CACCCTCAGC AGTTCAGCTC CTTCCACCAC AACCCCGCGC ATGACAGTAA CAGCCTCCCT
    GCTAGCCCCT TGAGGATAGT GGAGGATGAG GAGTATGAAA CGACCCAAGA GTACGAGCCA
    GCCCAAGAGC CTGTTAAGAA ACTCGCCAAT AGCCGGCGGG CCAAAAGAAC CAAGCCCAAT
    GGCCACATTG CTAACAGATT GGAAGTGGAC AGCAACACAA GCTCCCAGAG CAGTAACTCA
    GAGAGTGAAA CAGAAGATGA AAGAGTAGGT GAAGATACGC CTTTCCTGGG CATACAGAAC
    CCCCTGGCAG CCAGTCTTGA GGCAACACCT GCCTTCCGCC TGGCTGACAG CAGGACTAAC
    CCAGCAGGCC GCTTCTCGAC ACAGGAAGAA ATCCAGGCCA GGCTGTCTAG TGTAATTGCT
    AACCAAGACC CTATTGCTGT ATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001153467.1
    CDS151..1974
    Translation

    Target ORF information:

    RefSeq Version NM_001159995.3
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta1c, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001159995.3

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    ATGGGGAAAG GACGCGCGGG CCGAGTTGGC ACCACAGCCT TGCCTCCCCG ATTGAAAGAG 
    ATGAAAAGCC AGGAATCGGC TGCAGGTTCC AAACTAGTCC TTCGGTGTGA AACCAGTTCT
    GAATACTCCT CTCTCAGATT CAAGTGGTTC AAGAATGGGA ATGAATTGAA TCGAAAAAAC
    AAACCACAAA ATATCAAGAT ACAAAAAAAG CCAGGGAAGT CAGAACTTCG CATTAACAAA
    GCATCACTGG CTGATTCTGG AGAGTATATG TGCAAAGTGA TCAGCAAATT AGGAAATGAC
    AGTGCCTCTG CCAATATCAC CATCGTGGAA TCAAACGAGA TCATCACTGG TATGCCAGCC
    TCAACTGAAG GAGCATATGT GTCTTCAGCT ACATCTACAT CCACCACTGG GACAAGCCAT
    CTTGTAAAAT GTGCGGAGAA GGAGAAAACT TTCTGTGTGA ATGGAGGGGA GTGCTTCATG
    GTGAAAGACC TTTCAAACCC CTCGAGATAC TTGTGCAAGT GCCCAAATGA GTTTACTGGT
    GATCGCTGCC AAAACTACGT AATGGCCAGC TTCTACAAGC ATCTTGGGAT TGAATTTATG
    GAGGCGGAGG AGCTGTACCA GAAGAGAGTG CTGACCATAA CCGGCATCTG CATCGCCCTC
    CTTGTGGTCG GCATCATGTG TGTGGTGGCC TACTGCAAAA CCAAGAAACA GCGGAAAAAG
    CTGCATGACC GTCTTCGGCA GAGCCTTCGG TCTGAACGAA ACAATATGAT GAACATTGCC
    AATGGGCCTC ACCATCCTAA CCCACCCCCC GAGAATGTCC AGCTGGTGAA TCAATACGTA
    TCTAAAAACG TCATCTCCAG TGAGCATATT GTTGAGAGAG AAGCAGAGAC ATCCTTTTCC
    ACCAGTCACT ATACTTCCAC AGCCCATCAC TCCACTACTG TCACCCAGAC TCCTAGCCAC
    AGCTGGAGCA ACGGACACAC TGAAAGCATC CTTTCCGAAA GCCACTCTGT AATCGTGATG
    TCATCCGTAG AAAACAGTAG GCACAGCAGC CCAACTGGGG GCCCAAGAGG ACGTCTTAAT
    GGCACAGGAG GCCCTCGTGA ATGTAACAGC TTCCTCAGGC ATGCCAGAGA AACCCCTGAT
    TCCTACCGAG ACTCTCCTCA TAGTGAAAGG TATGTGTCAG CCATGACCAC CCCGGCTCGT
    ATGTCACCTG TAGATTTCCA CACGCCAAGC TCCCCCAAAT CGCCCCCTTC GGAAATGTCT
    CCACCCGTGT CCAGCATGAC GGTGTCCATG CCTTCCATGG CGGTCAGCCC CTTCATGGAA
    GAAGAGAGAC CTCTACTTCT CGTGACACCA CCAAGGCTGC GGGAGAAGAA GTTTGACCAT
    CACCCTCAGC AGTTCAGCTC CTTCCACCAC AACCCCGCGC ATGACAGTAA CAGCCTCCCT
    GCTAGCCCCT TGAGGATAGT GGAGGATGAG GAGTATGAAA CGACCCAAGA GTACGAGCCA
    GCCCAAGAGC CTGTTAAGAA ACTCGCCAAT AGCCGGCGGG CCAAAAGAAC CAAGCCCAAT
    GGCCACATTG CTAACAGATT GGAAGTGGAC AGCAACACAA GCTCCCAGAG CAGTAACTCA
    GAGAGTGAAA CAGAAGATGA AAGAGTAGGT GAAGATACGC CTTTCCTGGG CATACAGAAC
    CCCCTGGCAG CCAGTCTTGA GGCAACACCT GCCTTCCGCC TGGCTGACAG CAGGACTAAC
    CCAGCAGGCC GCTTCTCGAC ACAGGAAGAA ATCCAGGCCA GGCTGTCTAG TGTAATTGCT
    AACCAAGACC CTATTGCTGT ATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu28441
    Clone ID Related Accession (Same CDS sequence) NM_013956.3 , NM_013956.4 , NM_013956.5
    Accession Version NM_013956.3 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1938bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2015-03-14
    Organism Homo sapiens(Human)
    Product pro-neuregulin-1, membrane-bound isoform isoform HRG-beta1
    Comment

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTGCCCAA ATGAGTTTAC TGGTGATCGC
    TGCCAAAACT ACGTAATGGC CAGCTTCTAC AAGCATCTTG GGATTGAATT TATGGAGGCG
    GAGGAGCTGT ACCAGAAGAG AGTGCTGACC ATAACCGGCA TCTGCATCGC CCTCCTTGTG
    GTCGGCATCA TGTGTGTGGT GGCCTACTGC AAAACCAAGA AACAGCGGAA AAAGCTGCAT
    GACCGTCTTC GGCAGAGCCT TCGGTCTGAA CGAAACAATA TGATGAACAT TGCCAATGGG
    CCTCACCATC CTAACCCACC CCCCGAGAAT GTCCAGCTGG TGAATCAATA CGTATCTAAA
    AACGTCATCT CCAGTGAGCA TATTGTTGAG AGAGAAGCAG AGACATCCTT TTCCACCAGT
    CACTATACTT CCACAGCCCA TCACTCCACT ACTGTCACCC AGACTCCTAG CCACAGCTGG
    AGCAACGGAC ACACTGAAAG CATCCTTTCC GAAAGCCACT CTGTAATCGT GATGTCATCC
    GTAGAAAACA GTAGGCACAG CAGCCCAACT GGGGGCCCAA GAGGACGTCT TAATGGCACA
    GGAGGCCCTC GTGAATGTAA CAGCTTCCTC AGGCATGCCA GAGAAACCCC TGATTCCTAC
    CGAGACTCTC CTCATAGTGA AAGGTATGTG TCAGCCATGA CCACCCCGGC TCGTATGTCA
    CCTGTAGATT TCCACACGCC AAGCTCCCCC AAATCGCCCC CTTCGGAAAT GTCTCCACCC
    GTGTCCAGCA TGACGGTGTC CATGCCTTCC ATGGCGGTCA GCCCCTTCAT GGAAGAAGAG
    AGACCTCTAC TTCTCGTGAC ACCACCAAGG CTGCGGGAGA AGAAGTTTGA CCATCACCCT
    CAGCAGTTCA GCTCCTTCCA CCACAACCCC GCGCATGACA GTAACAGCCT CCCTGCTAGC
    CCCTTGAGGA TAGTGGAGGA TGAGGAGTAT GAAACGACCC AAGAGTACGA GCCAGCCCAA
    GAGCCTGTTA AGAAACTCGC CAATAGCCGG CGGGCCAAAA GAACCAAGCC CAATGGCCAC
    ATTGCTAACA GATTGGAAGT GGACAGCAAC ACAAGCTCCC AGAGCAGTAA CTCAGAGAGT
    GAAACAGAAG ATGAAAGAGT AGGTGAAGAT ACGCCTTTCC TGGGCATACA GAACCCCCTG
    GCAGCCAGTC TTGAGGCAAC ACCTGCCTTC CGCCTGGCTG ACAGCAGGAC TAACCCAGCA
    GGCCGCTTCT CGACACAGGA AGAAATCCAG GCCAGGCTGT CTAGTGTAAT TGCTAACCAA
    GACCCTATTG CTGTATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_039250.2
    Translation

    Target ORF information:

    RefSeq Version NM_013956.3
    Organism Homo sapiens(Human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_013956.3

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTGCCCAA ATGAGTTTAC TGGTGATCGC
    TGCCAAAACT ACGTAATGGC CAGCTTCTAC AAGCATCTTG GGATTGAATT TATGGAGGCG
    GAGGAGCTGT ACCAGAAGAG AGTGCTGACC ATAACCGGCA TCTGCATCGC CCTCCTTGTG
    GTCGGCATCA TGTGTGTGGT GGCCTACTGC AAAACCAAGA AACAGCGGAA AAAGCTGCAT
    GACCGTCTTC GGCAGAGCCT TCGGTCTGAA CGAAACAATA TGATGAACAT TGCCAATGGG
    CCTCACCATC CTAACCCACC CCCCGAGAAT GTCCAGCTGG TGAATCAATA CGTATCTAAA
    AACGTCATCT CCAGTGAGCA TATTGTTGAG AGAGAAGCAG AGACATCCTT TTCCACCAGT
    CACTATACTT CCACAGCCCA TCACTCCACT ACTGTCACCC AGACTCCTAG CCACAGCTGG
    AGCAACGGAC ACACTGAAAG CATCCTTTCC GAAAGCCACT CTGTAATCGT GATGTCATCC
    GTAGAAAACA GTAGGCACAG CAGCCCAACT GGGGGCCCAA GAGGACGTCT TAATGGCACA
    GGAGGCCCTC GTGAATGTAA CAGCTTCCTC AGGCATGCCA GAGAAACCCC TGATTCCTAC
    CGAGACTCTC CTCATAGTGA AAGGTATGTG TCAGCCATGA CCACCCCGGC TCGTATGTCA
    CCTGTAGATT TCCACACGCC AAGCTCCCCC AAATCGCCCC CTTCGGAAAT GTCTCCACCC
    GTGTCCAGCA TGACGGTGTC CATGCCTTCC ATGGCGGTCA GCCCCTTCAT GGAAGAAGAG
    AGACCTCTAC TTCTCGTGAC ACCACCAAGG CTGCGGGAGA AGAAGTTTGA CCATCACCCT
    CAGCAGTTCA GCTCCTTCCA CCACAACCCC GCGCATGACA GTAACAGCCT CCCTGCTAGC
    CCCTTGAGGA TAGTGGAGGA TGAGGAGTAT GAAACGACCC AAGAGTACGA GCCAGCCCAA
    GAGCCTGTTA AGAAACTCGC CAATAGCCGG CGGGCCAAAA GAACCAAGCC CAATGGCCAC
    ATTGCTAACA GATTGGAAGT GGACAGCAAC ACAAGCTCCC AGAGCAGTAA CTCAGAGAGT
    GAAACAGAAG ATGAAAGAGT AGGTGAAGAT ACGCCTTTCC TGGGCATACA GAACCCCCTG
    GCAGCCAGTC TTGAGGCAAC ACCTGCCTTC CGCCTGGCTG ACAGCAGGAC TAACCCAGCA
    GGCCGCTTCT CGACACAGGA AGAAATCCAG GCCAGGCTGT CTAGTGTAAT TGCTAACCAA
    GACCCTATTG CTGTATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu28441
    Clone ID Related Accession (Same CDS sequence) NM_013956.3 , NM_013956.4 , NM_013956.5
    Accession Version NM_013956.4 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1938bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2018-12-22
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform HRG-beta1
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK298132.1, AK097005.1, BC006492.2, BC144446.1, M94166.1, DA805080.1, AC113209.4 and CA429204.1. On Apr 8, 2016 this sequence version replaced NM_013956.3. Transcript Variant: This variant (HRG-beta1), which uses the type I promoter, encodes isoform HRG-beta1 (also known as NDF-beta1a or HRG-beta1a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M94166.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTGCCCAA ATGAGTTTAC TGGTGATCGC
    TGCCAAAACT ACGTAATGGC CAGCTTCTAC AAGCATCTTG GGATTGAATT TATGGAGGCG
    GAGGAGCTGT ACCAGAAGAG AGTGCTGACC ATAACCGGCA TCTGCATCGC CCTCCTTGTG
    GTCGGCATCA TGTGTGTGGT GGCCTACTGC AAAACCAAGA AACAGCGGAA AAAGCTGCAT
    GACCGTCTTC GGCAGAGCCT TCGGTCTGAA CGAAACAATA TGATGAACAT TGCCAATGGG
    CCTCACCATC CTAACCCACC CCCCGAGAAT GTCCAGCTGG TGAATCAATA CGTATCTAAA
    AACGTCATCT CCAGTGAGCA TATTGTTGAG AGAGAAGCAG AGACATCCTT TTCCACCAGT
    CACTATACTT CCACAGCCCA TCACTCCACT ACTGTCACCC AGACTCCTAG CCACAGCTGG
    AGCAACGGAC ACACTGAAAG CATCCTTTCC GAAAGCCACT CTGTAATCGT GATGTCATCC
    GTAGAAAACA GTAGGCACAG CAGCCCAACT GGGGGCCCAA GAGGACGTCT TAATGGCACA
    GGAGGCCCTC GTGAATGTAA CAGCTTCCTC AGGCATGCCA GAGAAACCCC TGATTCCTAC
    CGAGACTCTC CTCATAGTGA AAGGTATGTG TCAGCCATGA CCACCCCGGC TCGTATGTCA
    CCTGTAGATT TCCACACGCC AAGCTCCCCC AAATCGCCCC CTTCGGAAAT GTCTCCACCC
    GTGTCCAGCA TGACGGTGTC CATGCCTTCC ATGGCGGTCA GCCCCTTCAT GGAAGAAGAG
    AGACCTCTAC TTCTCGTGAC ACCACCAAGG CTGCGGGAGA AGAAGTTTGA CCATCACCCT
    CAGCAGTTCA GCTCCTTCCA CCACAACCCC GCGCATGACA GTAACAGCCT CCCTGCTAGC
    CCCTTGAGGA TAGTGGAGGA TGAGGAGTAT GAAACGACCC AAGAGTACGA GCCAGCCCAA
    GAGCCTGTTA AGAAACTCGC CAATAGCCGG CGGGCCAAAA GAACCAAGCC CAATGGCCAC
    ATTGCTAACA GATTGGAAGT GGACAGCAAC ACAAGCTCCC AGAGCAGTAA CTCAGAGAGT
    GAAACAGAAG ATGAAAGAGT AGGTGAAGAT ACGCCTTTCC TGGGCATACA GAACCCCCTG
    GCAGCCAGTC TTGAGGCAAC ACCTGCCTTC CGCCTGGCTG ACAGCAGGAC TAACCCAGCA
    GGCCGCTTCT CGACACAGGA AGAAATCCAG GCCAGGCTGT CTAGTGTAAT TGCTAACCAA
    GACCCTATTG CTGTATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_039250.2
    CDS518..2455
    Translation

    Target ORF information:

    RefSeq Version NM_013956.4
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_013956.4

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTGCCCAA ATGAGTTTAC TGGTGATCGC
    TGCCAAAACT ACGTAATGGC CAGCTTCTAC AAGCATCTTG GGATTGAATT TATGGAGGCG
    GAGGAGCTGT ACCAGAAGAG AGTGCTGACC ATAACCGGCA TCTGCATCGC CCTCCTTGTG
    GTCGGCATCA TGTGTGTGGT GGCCTACTGC AAAACCAAGA AACAGCGGAA AAAGCTGCAT
    GACCGTCTTC GGCAGAGCCT TCGGTCTGAA CGAAACAATA TGATGAACAT TGCCAATGGG
    CCTCACCATC CTAACCCACC CCCCGAGAAT GTCCAGCTGG TGAATCAATA CGTATCTAAA
    AACGTCATCT CCAGTGAGCA TATTGTTGAG AGAGAAGCAG AGACATCCTT TTCCACCAGT
    CACTATACTT CCACAGCCCA TCACTCCACT ACTGTCACCC AGACTCCTAG CCACAGCTGG
    AGCAACGGAC ACACTGAAAG CATCCTTTCC GAAAGCCACT CTGTAATCGT GATGTCATCC
    GTAGAAAACA GTAGGCACAG CAGCCCAACT GGGGGCCCAA GAGGACGTCT TAATGGCACA
    GGAGGCCCTC GTGAATGTAA CAGCTTCCTC AGGCATGCCA GAGAAACCCC TGATTCCTAC
    CGAGACTCTC CTCATAGTGA AAGGTATGTG TCAGCCATGA CCACCCCGGC TCGTATGTCA
    CCTGTAGATT TCCACACGCC AAGCTCCCCC AAATCGCCCC CTTCGGAAAT GTCTCCACCC
    GTGTCCAGCA TGACGGTGTC CATGCCTTCC ATGGCGGTCA GCCCCTTCAT GGAAGAAGAG
    AGACCTCTAC TTCTCGTGAC ACCACCAAGG CTGCGGGAGA AGAAGTTTGA CCATCACCCT
    CAGCAGTTCA GCTCCTTCCA CCACAACCCC GCGCATGACA GTAACAGCCT CCCTGCTAGC
    CCCTTGAGGA TAGTGGAGGA TGAGGAGTAT GAAACGACCC AAGAGTACGA GCCAGCCCAA
    GAGCCTGTTA AGAAACTCGC CAATAGCCGG CGGGCCAAAA GAACCAAGCC CAATGGCCAC
    ATTGCTAACA GATTGGAAGT GGACAGCAAC ACAAGCTCCC AGAGCAGTAA CTCAGAGAGT
    GAAACAGAAG ATGAAAGAGT AGGTGAAGAT ACGCCTTTCC TGGGCATACA GAACCCCCTG
    GCAGCCAGTC TTGAGGCAAC ACCTGCCTTC CGCCTGGCTG ACAGCAGGAC TAACCCAGCA
    GGCCGCTTCT CGACACAGGA AGAAATCCAG GCCAGGCTGT CTAGTGTAAT TGCTAACCAA
    GACCCTATTG CTGTATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu28441
    Clone ID Related Accession (Same CDS sequence) NM_013956.3 , NM_013956.4 , NM_013956.5
    Accession Version NM_013956.5 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1938bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-20
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform HRG-beta1
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK298132.1, AK097005.1, BC006492.2, BC144446.1, M94166.1, DA805080.1, AC113209.4 and CA429204.1. On Jun 2, 2019 this sequence version replaced NM_013956.4. Transcript Variant: This variant (HRG-beta1), which uses the type I promoter, encodes isoform HRG-beta1 (also known as NDF-beta1a or HRG-beta1a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M94166.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTGCCCAA ATGAGTTTAC TGGTGATCGC
    TGCCAAAACT ACGTAATGGC CAGCTTCTAC AAGCATCTTG GGATTGAATT TATGGAGGCG
    GAGGAGCTGT ACCAGAAGAG AGTGCTGACC ATAACCGGCA TCTGCATCGC CCTCCTTGTG
    GTCGGCATCA TGTGTGTGGT GGCCTACTGC AAAACCAAGA AACAGCGGAA AAAGCTGCAT
    GACCGTCTTC GGCAGAGCCT TCGGTCTGAA CGAAACAATA TGATGAACAT TGCCAATGGG
    CCTCACCATC CTAACCCACC CCCCGAGAAT GTCCAGCTGG TGAATCAATA CGTATCTAAA
    AACGTCATCT CCAGTGAGCA TATTGTTGAG AGAGAAGCAG AGACATCCTT TTCCACCAGT
    CACTATACTT CCACAGCCCA TCACTCCACT ACTGTCACCC AGACTCCTAG CCACAGCTGG
    AGCAACGGAC ACACTGAAAG CATCCTTTCC GAAAGCCACT CTGTAATCGT GATGTCATCC
    GTAGAAAACA GTAGGCACAG CAGCCCAACT GGGGGCCCAA GAGGACGTCT TAATGGCACA
    GGAGGCCCTC GTGAATGTAA CAGCTTCCTC AGGCATGCCA GAGAAACCCC TGATTCCTAC
    CGAGACTCTC CTCATAGTGA AAGGTATGTG TCAGCCATGA CCACCCCGGC TCGTATGTCA
    CCTGTAGATT TCCACACGCC AAGCTCCCCC AAATCGCCCC CTTCGGAAAT GTCTCCACCC
    GTGTCCAGCA TGACGGTGTC CATGCCTTCC ATGGCGGTCA GCCCCTTCAT GGAAGAAGAG
    AGACCTCTAC TTCTCGTGAC ACCACCAAGG CTGCGGGAGA AGAAGTTTGA CCATCACCCT
    CAGCAGTTCA GCTCCTTCCA CCACAACCCC GCGCATGACA GTAACAGCCT CCCTGCTAGC
    CCCTTGAGGA TAGTGGAGGA TGAGGAGTAT GAAACGACCC AAGAGTACGA GCCAGCCCAA
    GAGCCTGTTA AGAAACTCGC CAATAGCCGG CGGGCCAAAA GAACCAAGCC CAATGGCCAC
    ATTGCTAACA GATTGGAAGT GGACAGCAAC ACAAGCTCCC AGAGCAGTAA CTCAGAGAGT
    GAAACAGAAG ATGAAAGAGT AGGTGAAGAT ACGCCTTTCC TGGGCATACA GAACCCCCTG
    GCAGCCAGTC TTGAGGCAAC ACCTGCCTTC CGCCTGGCTG ACAGCAGGAC TAACCCAGCA
    GGCCGCTTCT CGACACAGGA AGAAATCCAG GCCAGGCTGT CTAGTGTAAT TGCTAACCAA
    GACCCTATTG CTGTATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_039250.2
    CDS417..2354
    Translation

    Target ORF information:

    RefSeq Version NM_013956.5
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_013956.5

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTGCCCAA ATGAGTTTAC TGGTGATCGC
    TGCCAAAACT ACGTAATGGC CAGCTTCTAC AAGCATCTTG GGATTGAATT TATGGAGGCG
    GAGGAGCTGT ACCAGAAGAG AGTGCTGACC ATAACCGGCA TCTGCATCGC CCTCCTTGTG
    GTCGGCATCA TGTGTGTGGT GGCCTACTGC AAAACCAAGA AACAGCGGAA AAAGCTGCAT
    GACCGTCTTC GGCAGAGCCT TCGGTCTGAA CGAAACAATA TGATGAACAT TGCCAATGGG
    CCTCACCATC CTAACCCACC CCCCGAGAAT GTCCAGCTGG TGAATCAATA CGTATCTAAA
    AACGTCATCT CCAGTGAGCA TATTGTTGAG AGAGAAGCAG AGACATCCTT TTCCACCAGT
    CACTATACTT CCACAGCCCA TCACTCCACT ACTGTCACCC AGACTCCTAG CCACAGCTGG
    AGCAACGGAC ACACTGAAAG CATCCTTTCC GAAAGCCACT CTGTAATCGT GATGTCATCC
    GTAGAAAACA GTAGGCACAG CAGCCCAACT GGGGGCCCAA GAGGACGTCT TAATGGCACA
    GGAGGCCCTC GTGAATGTAA CAGCTTCCTC AGGCATGCCA GAGAAACCCC TGATTCCTAC
    CGAGACTCTC CTCATAGTGA AAGGTATGTG TCAGCCATGA CCACCCCGGC TCGTATGTCA
    CCTGTAGATT TCCACACGCC AAGCTCCCCC AAATCGCCCC CTTCGGAAAT GTCTCCACCC
    GTGTCCAGCA TGACGGTGTC CATGCCTTCC ATGGCGGTCA GCCCCTTCAT GGAAGAAGAG
    AGACCTCTAC TTCTCGTGAC ACCACCAAGG CTGCGGGAGA AGAAGTTTGA CCATCACCCT
    CAGCAGTTCA GCTCCTTCCA CCACAACCCC GCGCATGACA GTAACAGCCT CCCTGCTAGC
    CCCTTGAGGA TAGTGGAGGA TGAGGAGTAT GAAACGACCC AAGAGTACGA GCCAGCCCAA
    GAGCCTGTTA AGAAACTCGC CAATAGCCGG CGGGCCAAAA GAACCAAGCC CAATGGCCAC
    ATTGCTAACA GATTGGAAGT GGACAGCAAC ACAAGCTCCC AGAGCAGTAA CTCAGAGAGT
    GAAACAGAAG ATGAAAGAGT AGGTGAAGAT ACGCCTTTCC TGGGCATACA GAACCCCCTG
    GCAGCCAGTC TTGAGGCAAC ACCTGCCTTC CGCCTGGCTG ACAGCAGGAC TAACCCAGCA
    GGCCGCTTCT CGACACAGGA AGAAATCCAG GCCAGGCTGT CTAGTGTAAT TGCTAACCAA
    GACCCTATTG CTGTATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu28453
    Clone ID Related Accession (Same CDS sequence) NM_001160008.2 , NM_001160008.1
    Accession Version NM_001160008.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1263bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-20
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform HRG-beta2b
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK298132.1, AK097005.1, BC006492.2, BQ018711.1 and AC113209.4. On Jun 2, 2019 this sequence version replaced NM_001160008.1. Transcript Variant: This variant (HRG-beta2b), which uses the type I promoter, lacks an alternate in-frame exon in the central coding region, and it also contains alternate 3' exon structure resulting an in early stop codon and alternate 3' UTR, compared to variant HRG-beta1. The resulting isoform (HRG-beta2b) lacks an internal segment and is shorter at the C-terminus, compared to isoform HRG-beta1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK298132.1, SRR5189667.174414.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTGCCCAA ATGAGTTTAC TGGTGATCGC
    TGCCAAAACT ACGTAATGGC CAGCTTCTAC AAGGCGGAGG AGCTGTACCA GAAGAGAGTG
    CTGACCATAA CCGGCATCTG CATCGCCCTC CTTGTGGTCG GCATCATGTG TGTGGTGGCC
    TACTGCAAAA CCAAGAAACA GCGGAAAAAG CTGCATGACC GTCTTCGGCA GAGCCTTCGG
    TCTGAACGAA ACAATATGAT GAACATTGCC AATGGGCCTC ACCATCCTAA CCCACCCCCC
    GAGAATGTCC AGCTGGTGAA TCAATACGTA TCTAAAAACG TCATCTCCAG TGAGCATATT
    GTTGAGAGAG AAGCAGAGAC ATCCTTTTCC ACCAGTCACT ATACTTCCAC AGCCCATCAC
    TCCACTACTG TCACCCAGAC TCCTAGCCAC AGCTGGAGCA ACGGACACAC TGAAAGCATC
    CTTTCCGAAA GCCACTCTGT AATCGTGATG TCATCCGTAG AAAACAGTAG GCACAGCAGC
    CCAACTGGGG GCCCAAGAGG ACGTCTTAAT GGCACAGGAG GCCCTCGTGA ATGTAACAGC
    TTCCTCAGGC ATGCCAGAGA AACCCCTGAT TCCTACCGAG ACTCTCCTCA TAGTGAAAGG
    TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001153480.1
    CDS417..1679
    Translation

    Target ORF information:

    RefSeq Version NM_001160008.2
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta2b, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001160008.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTGCCCAA ATGAGTTTAC TGGTGATCGC
    TGCCAAAACT ACGTAATGGC CAGCTTCTAC AAGGCGGAGG AGCTGTACCA GAAGAGAGTG
    CTGACCATAA CCGGCATCTG CATCGCCCTC CTTGTGGTCG GCATCATGTG TGTGGTGGCC
    TACTGCAAAA CCAAGAAACA GCGGAAAAAG CTGCATGACC GTCTTCGGCA GAGCCTTCGG
    TCTGAACGAA ACAATATGAT GAACATTGCC AATGGGCCTC ACCATCCTAA CCCACCCCCC
    GAGAATGTCC AGCTGGTGAA TCAATACGTA TCTAAAAACG TCATCTCCAG TGAGCATATT
    GTTGAGAGAG AAGCAGAGAC ATCCTTTTCC ACCAGTCACT ATACTTCCAC AGCCCATCAC
    TCCACTACTG TCACCCAGAC TCCTAGCCAC AGCTGGAGCA ACGGACACAC TGAAAGCATC
    CTTTCCGAAA GCCACTCTGT AATCGTGATG TCATCCGTAG AAAACAGTAG GCACAGCAGC
    CCAACTGGGG GCCCAAGAGG ACGTCTTAAT GGCACAGGAG GCCCTCGTGA ATGTAACAGC
    TTCCTCAGGC ATGCCAGAGA AACCCCTGAT TCCTACCGAG ACTCTCCTCA TAGTGAAAGG
    TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu28453
    Clone ID Related Accession (Same CDS sequence) NM_001160008.2 , NM_001160008.1
    Accession Version NM_001160008.1 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1263bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2018-12-22
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform HRG-beta2b
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK298132.1, AK097005.1, BC006492.2 and BQ018711.1. Transcript Variant: This variant (HRG-beta2b), which uses the type I promoter, lacks an alternate in-frame exon in the central coding region, and it also contains alternate 3' exon structure resulting an in early stop codon and alternate 3' UTR, compared to variant HRG-beta1. The resulting isoform (HRG-beta2b) lacks an internal segment and is shorter at the C-terminus, compared to isoform HRG-beta1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK298132.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTGCCCAA ATGAGTTTAC TGGTGATCGC
    TGCCAAAACT ACGTAATGGC CAGCTTCTAC AAGGCGGAGG AGCTGTACCA GAAGAGAGTG
    CTGACCATAA CCGGCATCTG CATCGCCCTC CTTGTGGTCG GCATCATGTG TGTGGTGGCC
    TACTGCAAAA CCAAGAAACA GCGGAAAAAG CTGCATGACC GTCTTCGGCA GAGCCTTCGG
    TCTGAACGAA ACAATATGAT GAACATTGCC AATGGGCCTC ACCATCCTAA CCCACCCCCC
    GAGAATGTCC AGCTGGTGAA TCAATACGTA TCTAAAAACG TCATCTCCAG TGAGCATATT
    GTTGAGAGAG AAGCAGAGAC ATCCTTTTCC ACCAGTCACT ATACTTCCAC AGCCCATCAC
    TCCACTACTG TCACCCAGAC TCCTAGCCAC AGCTGGAGCA ACGGACACAC TGAAAGCATC
    CTTTCCGAAA GCCACTCTGT AATCGTGATG TCATCCGTAG AAAACAGTAG GCACAGCAGC
    CCAACTGGGG GCCCAAGAGG ACGTCTTAAT GGCACAGGAG GCCCTCGTGA ATGTAACAGC
    TTCCTCAGGC ATGCCAGAGA AACCCCTGAT TCCTACCGAG ACTCTCCTCA TAGTGAAAGG
    TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001153480.1
    CDS518..1780
    Translation

    Target ORF information:

    RefSeq Version NM_001160008.1
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta2b, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001160008.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTGCCCAA ATGAGTTTAC TGGTGATCGC
    TGCCAAAACT ACGTAATGGC CAGCTTCTAC AAGGCGGAGG AGCTGTACCA GAAGAGAGTG
    CTGACCATAA CCGGCATCTG CATCGCCCTC CTTGTGGTCG GCATCATGTG TGTGGTGGCC
    TACTGCAAAA CCAAGAAACA GCGGAAAAAG CTGCATGACC GTCTTCGGCA GAGCCTTCGG
    TCTGAACGAA ACAATATGAT GAACATTGCC AATGGGCCTC ACCATCCTAA CCCACCCCCC
    GAGAATGTCC AGCTGGTGAA TCAATACGTA TCTAAAAACG TCATCTCCAG TGAGCATATT
    GTTGAGAGAG AAGCAGAGAC ATCCTTTTCC ACCAGTCACT ATACTTCCAC AGCCCATCAC
    TCCACTACTG TCACCCAGAC TCCTAGCCAC AGCTGGAGCA ACGGACACAC TGAAAGCATC
    CTTTCCGAAA GCCACTCTGT AATCGTGATG TCATCCGTAG AAAACAGTAG GCACAGCAGC
    CCAACTGGGG GCCCAAGAGG ACGTCTTAAT GGCACAGGAG GCCCTCGTGA ATGTAACAGC
    TTCCTCAGGC ATGCCAGAGA AACCCCTGAT TCCTACCGAG ACTCTCCTCA TAGTGAAAGG
    TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu28457
    Clone ID Related Accession (Same CDS sequence) NM_001159999.3 , NM_001159999.1 , NM_001159999.2
    Accession Version NM_001159999.3 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1875bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-20
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform HRG-beta1b
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from GQ983557.1, CN603652.1, EF517296.1, U02328.1, M94165.1, DA805080.1, AC113209.4 and CA429204.1. On Jun 2, 2019 this sequence version replaced NM_001159999.2. Transcript Variant: This variant (HRG-beta1b), which uses the type IV promoter, contains an alternate 5' terminal exon and thus differs in the 5' UTR and 5' coding region, compared to variant HRG-beta1. The resulting isoform (HRG-beta1b, also known as type IV fetal B beta 1a) has a distinct N-terminus and is shorter than isoform HRG-beta1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EF517296.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    ATGGGGAAAG GACGCGCGGG CCGAGTTGGC ACCACAGCCT TGCCTCCCCG ATTGAAAGAG 
    ATGAAAAGCC AGGAATCGGC TGCAGGTTCC AAACTAGTCC TTCGGTGTGA AACCAGTTCT
    GAATACTCCT CTCTCAGATT CAAGTGGTTC AAGAATGGGA ATGAATTGAA TCGAAAAAAC
    AAACCACAAA ATATCAAGAT ACAAAAAAAG CCAGGGAAGT CAGAACTTCG CATTAACAAA
    GCATCACTGG CTGATTCTGG AGAGTATATG TGCAAAGTGA TCAGCAAATT AGGAAATGAC
    AGTGCCTCTG CCAATATCAC CATCGTGGAA TCAAACGAGA TCATCACTGG TATGCCAGCC
    TCAACTGAAG GAGCATATGT GTCTTCAGAG TCTCCCATTA GAATATCAGT ATCCACAGAA
    GGAGCAAATA CTTCTTCATC TACATCTACA TCCACCACTG GGACAAGCCA TCTTGTAAAA
    TGTGCGGAGA AGGAGAAAAC TTTCTGTGTG AATGGAGGGG AGTGCTTCAT GGTGAAAGAC
    CTTTCAAACC CCTCGAGATA CTTGTGCAAG TGCCCAAATG AGTTTACTGG TGATCGCTGC
    CAAAACTACG TAATGGCCAG CTTCTACAAG CATCTTGGGA TTGAATTTAT GGAGGCGGAG
    GAGCTGTACC AGAAGAGAGT GCTGACCATA ACCGGCATCT GCATCGCCCT CCTTGTGGTC
    GGCATCATGT GTGTGGTGGC CTACTGCAAA ACCAAGAAAC AGCGGAAAAA GCTGCATGAC
    CGTCTTCGGC AGAGCCTTCG GTCTGAACGA AACAATATGA TGAACATTGC CAATGGGCCT
    CACCATCCTA ACCCACCCCC CGAGAATGTC CAGCTGGTGA ATCAATACGT ATCTAAAAAC
    GTCATCTCCA GTGAGCATAT TGTTGAGAGA GAAGCAGAGA CATCCTTTTC CACCAGTCAC
    TATACTTCCA CAGCCCATCA CTCCACTACT GTCACCCAGA CTCCTAGCCA CAGCTGGAGC
    AACGGACACA CTGAAAGCAT CCTTTCCGAA AGCCACTCTG TAATCGTGAT GTCATCCGTA
    GAAAACAGTA GGCACAGCAG CCCAACTGGG GGCCCAAGAG GACGTCTTAA TGGCACAGGA
    GGCCCTCGTG AATGTAACAG CTTCCTCAGG CATGCCAGAG AAACCCCTGA TTCCTACCGA
    GACTCTCCTC ATAGTGAAAG GTATGTGTCA GCCATGACCA CCCCGGCTCG TATGTCACCT
    GTAGATTTCC ACACGCCAAG CTCCCCCAAA TCGCCCCCTT CGGAAATGTC TCCACCCGTG
    TCCAGCATGA CGGTGTCCAT GCCTTCCATG GCGGTCAGCC CCTTCATGGA AGAAGAGAGA
    CCTCTACTTC TCGTGACACC ACCAAGGCTG CGGGAGAAGA AGTTTGACCA TCACCCTCAG
    CAGTTCAGCT CCTTCCACCA CAACCCCGCG CATGACAGTA ACAGCCTCCC TGCTAGCCCC
    TTGAGGATAG TGGAGGATGA GGAGTATGAA ACGACCCAAG AGTACGAGCC AGCCCAAGAG
    CCTGTTAAGA AACTCGCCAA TAGCCGGCGG GCCAAAAGAA CCAAGCCCAA TGGCCACATT
    GCTAACAGAT TGGAAGTGGA CAGCAACACA AGCTCCCAGA GCAGTAACTC AGAGAGTGAA
    ACAGAAGATG AAAGAGTAGG TGAAGATACG CCTTTCCTGG GCATACAGAA CCCCCTGGCA
    GCCAGTCTTG AGGCAACACC TGCCTTCCGC CTGGCTGACA GCAGGACTAA CCCAGCAGGC
    CGCTTCTCGA CACAGGAAGA AATCCAGGCC AGGCTGTCTA GTGTAATTGC TAACCAAGAC
    CCTATTGCTG TATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001153471.1
    CDS151..2025
    Translation

    Target ORF information:

    RefSeq Version NM_001159999.3
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta1b, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001159999.3

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    ATGGGGAAAG GACGCGCGGG CCGAGTTGGC ACCACAGCCT TGCCTCCCCG ATTGAAAGAG 
    ATGAAAAGCC AGGAATCGGC TGCAGGTTCC AAACTAGTCC TTCGGTGTGA AACCAGTTCT
    GAATACTCCT CTCTCAGATT CAAGTGGTTC AAGAATGGGA ATGAATTGAA TCGAAAAAAC
    AAACCACAAA ATATCAAGAT ACAAAAAAAG CCAGGGAAGT CAGAACTTCG CATTAACAAA
    GCATCACTGG CTGATTCTGG AGAGTATATG TGCAAAGTGA TCAGCAAATT AGGAAATGAC
    AGTGCCTCTG CCAATATCAC CATCGTGGAA TCAAACGAGA TCATCACTGG TATGCCAGCC
    TCAACTGAAG GAGCATATGT GTCTTCAGAG TCTCCCATTA GAATATCAGT ATCCACAGAA
    GGAGCAAATA CTTCTTCATC TACATCTACA TCCACCACTG GGACAAGCCA TCTTGTAAAA
    TGTGCGGAGA AGGAGAAAAC TTTCTGTGTG AATGGAGGGG AGTGCTTCAT GGTGAAAGAC
    CTTTCAAACC CCTCGAGATA CTTGTGCAAG TGCCCAAATG AGTTTACTGG TGATCGCTGC
    CAAAACTACG TAATGGCCAG CTTCTACAAG CATCTTGGGA TTGAATTTAT GGAGGCGGAG
    GAGCTGTACC AGAAGAGAGT GCTGACCATA ACCGGCATCT GCATCGCCCT CCTTGTGGTC
    GGCATCATGT GTGTGGTGGC CTACTGCAAA ACCAAGAAAC AGCGGAAAAA GCTGCATGAC
    CGTCTTCGGC AGAGCCTTCG GTCTGAACGA AACAATATGA TGAACATTGC CAATGGGCCT
    CACCATCCTA ACCCACCCCC CGAGAATGTC CAGCTGGTGA ATCAATACGT ATCTAAAAAC
    GTCATCTCCA GTGAGCATAT TGTTGAGAGA GAAGCAGAGA CATCCTTTTC CACCAGTCAC
    TATACTTCCA CAGCCCATCA CTCCACTACT GTCACCCAGA CTCCTAGCCA CAGCTGGAGC
    AACGGACACA CTGAAAGCAT CCTTTCCGAA AGCCACTCTG TAATCGTGAT GTCATCCGTA
    GAAAACAGTA GGCACAGCAG CCCAACTGGG GGCCCAAGAG GACGTCTTAA TGGCACAGGA
    GGCCCTCGTG AATGTAACAG CTTCCTCAGG CATGCCAGAG AAACCCCTGA TTCCTACCGA
    GACTCTCCTC ATAGTGAAAG GTATGTGTCA GCCATGACCA CCCCGGCTCG TATGTCACCT
    GTAGATTTCC ACACGCCAAG CTCCCCCAAA TCGCCCCCTT CGGAAATGTC TCCACCCGTG
    TCCAGCATGA CGGTGTCCAT GCCTTCCATG GCGGTCAGCC CCTTCATGGA AGAAGAGAGA
    CCTCTACTTC TCGTGACACC ACCAAGGCTG CGGGAGAAGA AGTTTGACCA TCACCCTCAG
    CAGTTCAGCT CCTTCCACCA CAACCCCGCG CATGACAGTA ACAGCCTCCC TGCTAGCCCC
    TTGAGGATAG TGGAGGATGA GGAGTATGAA ACGACCCAAG AGTACGAGCC AGCCCAAGAG
    CCTGTTAAGA AACTCGCCAA TAGCCGGCGG GCCAAAAGAA CCAAGCCCAA TGGCCACATT
    GCTAACAGAT TGGAAGTGGA CAGCAACACA AGCTCCCAGA GCAGTAACTC AGAGAGTGAA
    ACAGAAGATG AAAGAGTAGG TGAAGATACG CCTTTCCTGG GCATACAGAA CCCCCTGGCA
    GCCAGTCTTG AGGCAACACC TGCCTTCCGC CTGGCTGACA GCAGGACTAA CCCAGCAGGC
    CGCTTCTCGA CACAGGAAGA AATCCAGGCC AGGCTGTCTA GTGTAATTGC TAACCAAGAC
    CCTATTGCTG TATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu28457
    Clone ID Related Accession (Same CDS sequence) NM_001159999.3 , NM_001159999.1 , NM_001159999.2
    Accession Version NM_001159999.1 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1875bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2014-06-23
    Organism Homo sapiens(Human)
    Product pro-neuregulin-1, membrane-bound isoform isoform HRG-beta1b
    Comment

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    ATGGGGAAAG GACGCGCGGG CCGAGTTGGC ACCACAGCCT TGCCTCCCCG ATTGAAAGAG 
    ATGAAAAGCC AGGAATCGGC TGCAGGTTCC AAACTAGTCC TTCGGTGTGA AACCAGTTCT
    GAATACTCCT CTCTCAGATT CAAGTGGTTC AAGAATGGGA ATGAATTGAA TCGAAAAAAC
    AAACCACAAA ATATCAAGAT ACAAAAAAAG CCAGGGAAGT CAGAACTTCG CATTAACAAA
    GCATCACTGG CTGATTCTGG AGAGTATATG TGCAAAGTGA TCAGCAAATT AGGAAATGAC
    AGTGCCTCTG CCAATATCAC CATCGTGGAA TCAAACGAGA TCATCACTGG TATGCCAGCC
    TCAACTGAAG GAGCATATGT GTCTTCAGAG TCTCCCATTA GAATATCAGT ATCCACAGAA
    GGAGCAAATA CTTCTTCATC TACATCTACA TCCACCACTG GGACAAGCCA TCTTGTAAAA
    TGTGCGGAGA AGGAGAAAAC TTTCTGTGTG AATGGAGGGG AGTGCTTCAT GGTGAAAGAC
    CTTTCAAACC CCTCGAGATA CTTGTGCAAG TGCCCAAATG AGTTTACTGG TGATCGCTGC
    CAAAACTACG TAATGGCCAG CTTCTACAAG CATCTTGGGA TTGAATTTAT GGAGGCGGAG
    GAGCTGTACC AGAAGAGAGT GCTGACCATA ACCGGCATCT GCATCGCCCT CCTTGTGGTC
    GGCATCATGT GTGTGGTGGC CTACTGCAAA ACCAAGAAAC AGCGGAAAAA GCTGCATGAC
    CGTCTTCGGC AGAGCCTTCG GTCTGAACGA AACAATATGA TGAACATTGC CAATGGGCCT
    CACCATCCTA ACCCACCCCC CGAGAATGTC CAGCTGGTGA ATCAATACGT ATCTAAAAAC
    GTCATCTCCA GTGAGCATAT TGTTGAGAGA GAAGCAGAGA CATCCTTTTC CACCAGTCAC
    TATACTTCCA CAGCCCATCA CTCCACTACT GTCACCCAGA CTCCTAGCCA CAGCTGGAGC
    AACGGACACA CTGAAAGCAT CCTTTCCGAA AGCCACTCTG TAATCGTGAT GTCATCCGTA
    GAAAACAGTA GGCACAGCAG CCCAACTGGG GGCCCAAGAG GACGTCTTAA TGGCACAGGA
    GGCCCTCGTG AATGTAACAG CTTCCTCAGG CATGCCAGAG AAACCCCTGA TTCCTACCGA
    GACTCTCCTC ATAGTGAAAG GTATGTGTCA GCCATGACCA CCCCGGCTCG TATGTCACCT
    GTAGATTTCC ACACGCCAAG CTCCCCCAAA TCGCCCCCTT CGGAAATGTC TCCACCCGTG
    TCCAGCATGA CGGTGTCCAT GCCTTCCATG GCGGTCAGCC CCTTCATGGA AGAAGAGAGA
    CCTCTACTTC TCGTGACACC ACCAAGGCTG CGGGAGAAGA AGTTTGACCA TCACCCTCAG
    CAGTTCAGCT CCTTCCACCA CAACCCCGCG CATGACAGTA ACAGCCTCCC TGCTAGCCCC
    TTGAGGATAG TGGAGGATGA GGAGTATGAA ACGACCCAAG AGTACGAGCC AGCCCAAGAG
    CCTGTTAAGA AACTCGCCAA TAGCCGGCGG GCCAAAAGAA CCAAGCCCAA TGGCCACATT
    GCTAACAGAT TGGAAGTGGA CAGCAACACA AGCTCCCAGA GCAGTAACTC AGAGAGTGAA
    ACAGAAGATG AAAGAGTAGG TGAAGATACG CCTTTCCTGG GCATACAGAA CCCCCTGGCA
    GCCAGTCTTG AGGCAACACC TGCCTTCCGC CTGGCTGACA GCAGGACTAA CCCAGCAGGC
    CGCTTCTCGA CACAGGAAGA AATCCAGGCC AGGCTGTCTA GTGTAATTGC TAACCAAGAC
    CCTATTGCTG TATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001153471.1
    Translation

    Target ORF information:

    RefSeq Version NM_001159999.1
    Organism Homo sapiens(Human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta1b, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001159999.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    ATGGGGAAAG GACGCGCGGG CCGAGTTGGC ACCACAGCCT TGCCTCCCCG ATTGAAAGAG 
    ATGAAAAGCC AGGAATCGGC TGCAGGTTCC AAACTAGTCC TTCGGTGTGA AACCAGTTCT
    GAATACTCCT CTCTCAGATT CAAGTGGTTC AAGAATGGGA ATGAATTGAA TCGAAAAAAC
    AAACCACAAA ATATCAAGAT ACAAAAAAAG CCAGGGAAGT CAGAACTTCG CATTAACAAA
    GCATCACTGG CTGATTCTGG AGAGTATATG TGCAAAGTGA TCAGCAAATT AGGAAATGAC
    AGTGCCTCTG CCAATATCAC CATCGTGGAA TCAAACGAGA TCATCACTGG TATGCCAGCC
    TCAACTGAAG GAGCATATGT GTCTTCAGAG TCTCCCATTA GAATATCAGT ATCCACAGAA
    GGAGCAAATA CTTCTTCATC TACATCTACA TCCACCACTG GGACAAGCCA TCTTGTAAAA
    TGTGCGGAGA AGGAGAAAAC TTTCTGTGTG AATGGAGGGG AGTGCTTCAT GGTGAAAGAC
    CTTTCAAACC CCTCGAGATA CTTGTGCAAG TGCCCAAATG AGTTTACTGG TGATCGCTGC
    CAAAACTACG TAATGGCCAG CTTCTACAAG CATCTTGGGA TTGAATTTAT GGAGGCGGAG
    GAGCTGTACC AGAAGAGAGT GCTGACCATA ACCGGCATCT GCATCGCCCT CCTTGTGGTC
    GGCATCATGT GTGTGGTGGC CTACTGCAAA ACCAAGAAAC AGCGGAAAAA GCTGCATGAC
    CGTCTTCGGC AGAGCCTTCG GTCTGAACGA AACAATATGA TGAACATTGC CAATGGGCCT
    CACCATCCTA ACCCACCCCC CGAGAATGTC CAGCTGGTGA ATCAATACGT ATCTAAAAAC
    GTCATCTCCA GTGAGCATAT TGTTGAGAGA GAAGCAGAGA CATCCTTTTC CACCAGTCAC
    TATACTTCCA CAGCCCATCA CTCCACTACT GTCACCCAGA CTCCTAGCCA CAGCTGGAGC
    AACGGACACA CTGAAAGCAT CCTTTCCGAA AGCCACTCTG TAATCGTGAT GTCATCCGTA
    GAAAACAGTA GGCACAGCAG CCCAACTGGG GGCCCAAGAG GACGTCTTAA TGGCACAGGA
    GGCCCTCGTG AATGTAACAG CTTCCTCAGG CATGCCAGAG AAACCCCTGA TTCCTACCGA
    GACTCTCCTC ATAGTGAAAG GTATGTGTCA GCCATGACCA CCCCGGCTCG TATGTCACCT
    GTAGATTTCC ACACGCCAAG CTCCCCCAAA TCGCCCCCTT CGGAAATGTC TCCACCCGTG
    TCCAGCATGA CGGTGTCCAT GCCTTCCATG GCGGTCAGCC CCTTCATGGA AGAAGAGAGA
    CCTCTACTTC TCGTGACACC ACCAAGGCTG CGGGAGAAGA AGTTTGACCA TCACCCTCAG
    CAGTTCAGCT CCTTCCACCA CAACCCCGCG CATGACAGTA ACAGCCTCCC TGCTAGCCCC
    TTGAGGATAG TGGAGGATGA GGAGTATGAA ACGACCCAAG AGTACGAGCC AGCCCAAGAG
    CCTGTTAAGA AACTCGCCAA TAGCCGGCGG GCCAAAAGAA CCAAGCCCAA TGGCCACATT
    GCTAACAGAT TGGAAGTGGA CAGCAACACA AGCTCCCAGA GCAGTAACTC AGAGAGTGAA
    ACAGAAGATG AAAGAGTAGG TGAAGATACG CCTTTCCTGG GCATACAGAA CCCCCTGGCA
    GCCAGTCTTG AGGCAACACC TGCCTTCCGC CTGGCTGACA GCAGGACTAA CCCAGCAGGC
    CGCTTCTCGA CACAGGAAGA AATCCAGGCC AGGCTGTCTA GTGTAATTGC TAACCAAGAC
    CCTATTGCTG TATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu28457
    Clone ID Related Accession (Same CDS sequence) NM_001159999.3 , NM_001159999.1 , NM_001159999.2
    Accession Version NM_001159999.2 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1875bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2018-12-22
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform HRG-beta1b
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from GQ983557.1, CN603652.1, EF517296.1, U02328.1, M94165.1, DA805080.1, AC113209.4 and CA429204.1. On Apr 8, 2016 this sequence version replaced NM_001159999.1. Transcript Variant: This variant (HRG-beta1b), which uses the type IV promoter, contains an alternate 5' terminal exon and thus differs in the 5' UTR and 5' coding region, compared to variant HRG-beta1. The resulting isoform (HRG-beta1b, also known as type IV fetal B beta 1a) has a distinct N-terminus and is shorter than isoform HRG-beta1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EF517296.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    ATGGGGAAAG GACGCGCGGG CCGAGTTGGC ACCACAGCCT TGCCTCCCCG ATTGAAAGAG 
    ATGAAAAGCC AGGAATCGGC TGCAGGTTCC AAACTAGTCC TTCGGTGTGA AACCAGTTCT
    GAATACTCCT CTCTCAGATT CAAGTGGTTC AAGAATGGGA ATGAATTGAA TCGAAAAAAC
    AAACCACAAA ATATCAAGAT ACAAAAAAAG CCAGGGAAGT CAGAACTTCG CATTAACAAA
    GCATCACTGG CTGATTCTGG AGAGTATATG TGCAAAGTGA TCAGCAAATT AGGAAATGAC
    AGTGCCTCTG CCAATATCAC CATCGTGGAA TCAAACGAGA TCATCACTGG TATGCCAGCC
    TCAACTGAAG GAGCATATGT GTCTTCAGAG TCTCCCATTA GAATATCAGT ATCCACAGAA
    GGAGCAAATA CTTCTTCATC TACATCTACA TCCACCACTG GGACAAGCCA TCTTGTAAAA
    TGTGCGGAGA AGGAGAAAAC TTTCTGTGTG AATGGAGGGG AGTGCTTCAT GGTGAAAGAC
    CTTTCAAACC CCTCGAGATA CTTGTGCAAG TGCCCAAATG AGTTTACTGG TGATCGCTGC
    CAAAACTACG TAATGGCCAG CTTCTACAAG CATCTTGGGA TTGAATTTAT GGAGGCGGAG
    GAGCTGTACC AGAAGAGAGT GCTGACCATA ACCGGCATCT GCATCGCCCT CCTTGTGGTC
    GGCATCATGT GTGTGGTGGC CTACTGCAAA ACCAAGAAAC AGCGGAAAAA GCTGCATGAC
    CGTCTTCGGC AGAGCCTTCG GTCTGAACGA AACAATATGA TGAACATTGC CAATGGGCCT
    CACCATCCTA ACCCACCCCC CGAGAATGTC CAGCTGGTGA ATCAATACGT ATCTAAAAAC
    GTCATCTCCA GTGAGCATAT TGTTGAGAGA GAAGCAGAGA CATCCTTTTC CACCAGTCAC
    TATACTTCCA CAGCCCATCA CTCCACTACT GTCACCCAGA CTCCTAGCCA CAGCTGGAGC
    AACGGACACA CTGAAAGCAT CCTTTCCGAA AGCCACTCTG TAATCGTGAT GTCATCCGTA
    GAAAACAGTA GGCACAGCAG CCCAACTGGG GGCCCAAGAG GACGTCTTAA TGGCACAGGA
    GGCCCTCGTG AATGTAACAG CTTCCTCAGG CATGCCAGAG AAACCCCTGA TTCCTACCGA
    GACTCTCCTC ATAGTGAAAG GTATGTGTCA GCCATGACCA CCCCGGCTCG TATGTCACCT
    GTAGATTTCC ACACGCCAAG CTCCCCCAAA TCGCCCCCTT CGGAAATGTC TCCACCCGTG
    TCCAGCATGA CGGTGTCCAT GCCTTCCATG GCGGTCAGCC CCTTCATGGA AGAAGAGAGA
    CCTCTACTTC TCGTGACACC ACCAAGGCTG CGGGAGAAGA AGTTTGACCA TCACCCTCAG
    CAGTTCAGCT CCTTCCACCA CAACCCCGCG CATGACAGTA ACAGCCTCCC TGCTAGCCCC
    TTGAGGATAG TGGAGGATGA GGAGTATGAA ACGACCCAAG AGTACGAGCC AGCCCAAGAG
    CCTGTTAAGA AACTCGCCAA TAGCCGGCGG GCCAAAAGAA CCAAGCCCAA TGGCCACATT
    GCTAACAGAT TGGAAGTGGA CAGCAACACA AGCTCCCAGA GCAGTAACTC AGAGAGTGAA
    ACAGAAGATG AAAGAGTAGG TGAAGATACG CCTTTCCTGG GCATACAGAA CCCCCTGGCA
    GCCAGTCTTG AGGCAACACC TGCCTTCCGC CTGGCTGACA GCAGGACTAA CCCAGCAGGC
    CGCTTCTCGA CACAGGAAGA AATCCAGGCC AGGCTGTCTA GTGTAATTGC TAACCAAGAC
    CCTATTGCTG TATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001153471.1
    CDS174..2048
    Translation

    Target ORF information:

    RefSeq Version NM_001159999.2
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta1b, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001159999.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    ATGGGGAAAG GACGCGCGGG CCGAGTTGGC ACCACAGCCT TGCCTCCCCG ATTGAAAGAG 
    ATGAAAAGCC AGGAATCGGC TGCAGGTTCC AAACTAGTCC TTCGGTGTGA AACCAGTTCT
    GAATACTCCT CTCTCAGATT CAAGTGGTTC AAGAATGGGA ATGAATTGAA TCGAAAAAAC
    AAACCACAAA ATATCAAGAT ACAAAAAAAG CCAGGGAAGT CAGAACTTCG CATTAACAAA
    GCATCACTGG CTGATTCTGG AGAGTATATG TGCAAAGTGA TCAGCAAATT AGGAAATGAC
    AGTGCCTCTG CCAATATCAC CATCGTGGAA TCAAACGAGA TCATCACTGG TATGCCAGCC
    TCAACTGAAG GAGCATATGT GTCTTCAGAG TCTCCCATTA GAATATCAGT ATCCACAGAA
    GGAGCAAATA CTTCTTCATC TACATCTACA TCCACCACTG GGACAAGCCA TCTTGTAAAA
    TGTGCGGAGA AGGAGAAAAC TTTCTGTGTG AATGGAGGGG AGTGCTTCAT GGTGAAAGAC
    CTTTCAAACC CCTCGAGATA CTTGTGCAAG TGCCCAAATG AGTTTACTGG TGATCGCTGC
    CAAAACTACG TAATGGCCAG CTTCTACAAG CATCTTGGGA TTGAATTTAT GGAGGCGGAG
    GAGCTGTACC AGAAGAGAGT GCTGACCATA ACCGGCATCT GCATCGCCCT CCTTGTGGTC
    GGCATCATGT GTGTGGTGGC CTACTGCAAA ACCAAGAAAC AGCGGAAAAA GCTGCATGAC
    CGTCTTCGGC AGAGCCTTCG GTCTGAACGA AACAATATGA TGAACATTGC CAATGGGCCT
    CACCATCCTA ACCCACCCCC CGAGAATGTC CAGCTGGTGA ATCAATACGT ATCTAAAAAC
    GTCATCTCCA GTGAGCATAT TGTTGAGAGA GAAGCAGAGA CATCCTTTTC CACCAGTCAC
    TATACTTCCA CAGCCCATCA CTCCACTACT GTCACCCAGA CTCCTAGCCA CAGCTGGAGC
    AACGGACACA CTGAAAGCAT CCTTTCCGAA AGCCACTCTG TAATCGTGAT GTCATCCGTA
    GAAAACAGTA GGCACAGCAG CCCAACTGGG GGCCCAAGAG GACGTCTTAA TGGCACAGGA
    GGCCCTCGTG AATGTAACAG CTTCCTCAGG CATGCCAGAG AAACCCCTGA TTCCTACCGA
    GACTCTCCTC ATAGTGAAAG GTATGTGTCA GCCATGACCA CCCCGGCTCG TATGTCACCT
    GTAGATTTCC ACACGCCAAG CTCCCCCAAA TCGCCCCCTT CGGAAATGTC TCCACCCGTG
    TCCAGCATGA CGGTGTCCAT GCCTTCCATG GCGGTCAGCC CCTTCATGGA AGAAGAGAGA
    CCTCTACTTC TCGTGACACC ACCAAGGCTG CGGGAGAAGA AGTTTGACCA TCACCCTCAG
    CAGTTCAGCT CCTTCCACCA CAACCCCGCG CATGACAGTA ACAGCCTCCC TGCTAGCCCC
    TTGAGGATAG TGGAGGATGA GGAGTATGAA ACGACCCAAG AGTACGAGCC AGCCCAAGAG
    CCTGTTAAGA AACTCGCCAA TAGCCGGCGG GCCAAAAGAA CCAAGCCCAA TGGCCACATT
    GCTAACAGAT TGGAAGTGGA CAGCAACACA AGCTCCCAGA GCAGTAACTC AGAGAGTGAA
    ACAGAAGATG AAAGAGTAGG TGAAGATACG CCTTTCCTGG GCATACAGAA CCCCCTGGCA
    GCCAGTCTTG AGGCAACACC TGCCTTCCGC CTGGCTGACA GCAGGACTAA CCCAGCAGGC
    CGCTTCTCGA CACAGGAAGA AATCCAGGCC AGGCTGTCTA GTGTAATTGC TAACCAAGAC
    CCTATTGCTG TATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu42053
    Clone ID Related Accession (Same CDS sequence) NM_001322205.1 , NM_001322205.2
    Accession Version NM_001322205.1 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 2103bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2018-12-22
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform NRG-III-beta1a
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK289927.1, EF517295.1, AC103675.2, AC113209.4 and CA429204.1. On Apr 7, 2016 this sequence version replaced XM_005273485.2. Transcript Variant: This variant (NRG-III-beta1a), which uses the type III promoter, lacks several 5' exons but contains an alternate 5' terminal exon, and it thus differs in the 5' UTR and 5' coding region, compared to variant HRG-beta1. The resulting isoform (NRG-III-beta1a, also known as nARIAbeta1a or CRD-NRGbeta1a) has a distinct N-terminus and is longer than isoform HRG-beta1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.218616.1, SRR1803612.233163.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2151358 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    ATGGAGATTT ATTCCCCAGA CATGTCTGAG GTCGCCGCCG AGAGGTCCTC CAGCCCCTCC 
    ACTCAGCTGA GTGCAGACCC ATCTCTTGAT GGGCTTCCGG CAGCAGAAGA CATGCCAGAG
    CCCCAGACTG AAGATGGGAG AACCCCTGGA CTCGTGGGCC TGGCCGTGCC CTGCTGTGCG
    TGCCTAGAAG CTGAGCGCCT GAGAGGTTGC CTCAACTCAG AGAAAATCTG CATTGTCCCC
    ATCCTGGCTT GCCTGGTCAG CCTCTGCCTC TGCATCGCCG GCCTCAAGTG GGTATTTGTG
    GACAAGATCT TTGAATATGA CTCTCCTACT CACCTTGACC CTGGGGGGTT AGGCCAGGAC
    CCTATTATTT CTCTGGACGC AACTGCTGCC TCAGCTGTGT GGGTGTCGTC TGAGGCATAC
    ACTTCACCTG TCTCTAGGGC TCAATCTGAA AGTGAGGTTC AAGTTACAGT GCAAGGTGAC
    AAGGCTGTTG TCTCCTTTGA ACCATCAGCG GCACCGACAC CGAAGAATCG TATTTTTGCC
    TTTTCTTTCT TGCCGTCCAC TGCGCCATCC TTCCCTTCAC CCACCCGGAA CCCTGAGGTG
    AGAACGCCCA AGTCAGCAAC TCAGCCACAA ACAACAGAAA CTAATCTCCA AACTGCTCCT
    AAACTTTCTA CATCTACATC CACCACTGGG ACAAGCCATC TTGTAAAATG TGCGGAGAAG
    GAGAAAACTT TCTGTGTGAA TGGAGGGGAG TGCTTCATGG TGAAAGACCT TTCAAACCCC
    TCGAGATACT TGTGCAAGTG CCCAAATGAG TTTACTGGTG ATCGCTGCCA AAACTACGTA
    ATGGCCAGCT TCTACAAGCA TCTTGGGATT GAATTTATGG AGGCGGAGGA GCTGTACCAG
    AAGAGAGTGC TGACCATAAC CGGCATCTGC ATCGCCCTCC TTGTGGTCGG CATCATGTGT
    GTGGTGGCCT ACTGCAAAAC CAAGAAACAG CGGAAAAAGC TGCATGACCG TCTTCGGCAG
    AGCCTTCGGT CTGAACGAAA CAATATGATG AACATTGCCA ATGGGCCTCA CCATCCTAAC
    CCACCCCCCG AGAATGTCCA GCTGGTGAAT CAATACGTAT CTAAAAACGT CATCTCCAGT
    GAGCATATTG TTGAGAGAGA AGCAGAGACA TCCTTTTCCA CCAGTCACTA TACTTCCACA
    GCCCATCACT CCACTACTGT CACCCAGACT CCTAGCCACA GCTGGAGCAA CGGACACACT
    GAAAGCATCC TTTCCGAAAG CCACTCTGTA ATCGTGATGT CATCCGTAGA AAACAGTAGG
    CACAGCAGCC CAACTGGGGG CCCAAGAGGA CGTCTTAATG GCACAGGAGG CCCTCGTGAA
    TGTAACAGCT TCCTCAGGCA TGCCAGAGAA ACCCCTGATT CCTACCGAGA CTCTCCTCAT
    AGTGAAAGGT ATGTGTCAGC CATGACCACC CCGGCTCGTA TGTCACCTGT AGATTTCCAC
    ACGCCAAGCT CCCCCAAATC GCCCCCTTCG GAAATGTCTC CACCCGTGTC CAGCATGACG
    GTGTCCATGC CTTCCATGGC GGTCAGCCCC TTCATGGAAG AAGAGAGACC TCTACTTCTC
    GTGACACCAC CAAGGCTGCG GGAGAAGAAG TTTGACCATC ACCCTCAGCA GTTCAGCTCC
    TTCCACCACA ACCCCGCGCA TGACAGTAAC AGCCTCCCTG CTAGCCCCTT GAGGATAGTG
    GAGGATGAGG AGTATGAAAC GACCCAAGAG TACGAGCCAG CCCAAGAGCC TGTTAAGAAA
    CTCGCCAATA GCCGGCGGGC CAAAAGAACC AAGCCCAATG GCCACATTGC TAACAGATTG
    GAAGTGGACA GCAACACAAG CTCCCAGAGC AGTAACTCAG AGAGTGAAAC AGAAGATGAA
    AGAGTAGGTG AAGATACGCC TTTCCTGGGC ATACAGAACC CCCTGGCAGC CAGTCTTGAG
    GCAACACCTG CCTTCCGCCT GGCTGACAGC AGGACTAACC CAGCAGGCCG CTTCTCGACA
    CAGGAAGAAA TCCAGGCCAG GCTGTCTAGT GTAATTGCTA ACCAAGACCC TATTGCTGTA
    TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001309134.1
    CDS987..3089
    Translation

    Target ORF information:

    RefSeq Version NM_001322205.1
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant NRG-III-beta1a, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001322205.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    ATGGAGATTT ATTCCCCAGA CATGTCTGAG GTCGCCGCCG AGAGGTCCTC CAGCCCCTCC 
    ACTCAGCTGA GTGCAGACCC ATCTCTTGAT GGGCTTCCGG CAGCAGAAGA CATGCCAGAG
    CCCCAGACTG AAGATGGGAG AACCCCTGGA CTCGTGGGCC TGGCCGTGCC CTGCTGTGCG
    TGCCTAGAAG CTGAGCGCCT GAGAGGTTGC CTCAACTCAG AGAAAATCTG CATTGTCCCC
    ATCCTGGCTT GCCTGGTCAG CCTCTGCCTC TGCATCGCCG GCCTCAAGTG GGTATTTGTG
    GACAAGATCT TTGAATATGA CTCTCCTACT CACCTTGACC CTGGGGGGTT AGGCCAGGAC
    CCTATTATTT CTCTGGACGC AACTGCTGCC TCAGCTGTGT GGGTGTCGTC TGAGGCATAC
    ACTTCACCTG TCTCTAGGGC TCAATCTGAA AGTGAGGTTC AAGTTACAGT GCAAGGTGAC
    AAGGCTGTTG TCTCCTTTGA ACCATCAGCG GCACCGACAC CGAAGAATCG TATTTTTGCC
    TTTTCTTTCT TGCCGTCCAC TGCGCCATCC TTCCCTTCAC CCACCCGGAA CCCTGAGGTG
    AGAACGCCCA AGTCAGCAAC TCAGCCACAA ACAACAGAAA CTAATCTCCA AACTGCTCCT
    AAACTTTCTA CATCTACATC CACCACTGGG ACAAGCCATC TTGTAAAATG TGCGGAGAAG
    GAGAAAACTT TCTGTGTGAA TGGAGGGGAG TGCTTCATGG TGAAAGACCT TTCAAACCCC
    TCGAGATACT TGTGCAAGTG CCCAAATGAG TTTACTGGTG ATCGCTGCCA AAACTACGTA
    ATGGCCAGCT TCTACAAGCA TCTTGGGATT GAATTTATGG AGGCGGAGGA GCTGTACCAG
    AAGAGAGTGC TGACCATAAC CGGCATCTGC ATCGCCCTCC TTGTGGTCGG CATCATGTGT
    GTGGTGGCCT ACTGCAAAAC CAAGAAACAG CGGAAAAAGC TGCATGACCG TCTTCGGCAG
    AGCCTTCGGT CTGAACGAAA CAATATGATG AACATTGCCA ATGGGCCTCA CCATCCTAAC
    CCACCCCCCG AGAATGTCCA GCTGGTGAAT CAATACGTAT CTAAAAACGT CATCTCCAGT
    GAGCATATTG TTGAGAGAGA AGCAGAGACA TCCTTTTCCA CCAGTCACTA TACTTCCACA
    GCCCATCACT CCACTACTGT CACCCAGACT CCTAGCCACA GCTGGAGCAA CGGACACACT
    GAAAGCATCC TTTCCGAAAG CCACTCTGTA ATCGTGATGT CATCCGTAGA AAACAGTAGG
    CACAGCAGCC CAACTGGGGG CCCAAGAGGA CGTCTTAATG GCACAGGAGG CCCTCGTGAA
    TGTAACAGCT TCCTCAGGCA TGCCAGAGAA ACCCCTGATT CCTACCGAGA CTCTCCTCAT
    AGTGAAAGGT ATGTGTCAGC CATGACCACC CCGGCTCGTA TGTCACCTGT AGATTTCCAC
    ACGCCAAGCT CCCCCAAATC GCCCCCTTCG GAAATGTCTC CACCCGTGTC CAGCATGACG
    GTGTCCATGC CTTCCATGGC GGTCAGCCCC TTCATGGAAG AAGAGAGACC TCTACTTCTC
    GTGACACCAC CAAGGCTGCG GGAGAAGAAG TTTGACCATC ACCCTCAGCA GTTCAGCTCC
    TTCCACCACA ACCCCGCGCA TGACAGTAAC AGCCTCCCTG CTAGCCCCTT GAGGATAGTG
    GAGGATGAGG AGTATGAAAC GACCCAAGAG TACGAGCCAG CCCAAGAGCC TGTTAAGAAA
    CTCGCCAATA GCCGGCGGGC CAAAAGAACC AAGCCCAATG GCCACATTGC TAACAGATTG
    GAAGTGGACA GCAACACAAG CTCCCAGAGC AGTAACTCAG AGAGTGAAAC AGAAGATGAA
    AGAGTAGGTG AAGATACGCC TTTCCTGGGC ATACAGAACC CCCTGGCAGC CAGTCTTGAG
    GCAACACCTG CCTTCCGCCT GGCTGACAGC AGGACTAACC CAGCAGGCCG CTTCTCGACA
    CAGGAAGAAA TCCAGGCCAG GCTGTCTAGT GTAATTGCTA ACCAAGACCC TATTGCTGTA
    TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu42053
    Clone ID Related Accession (Same CDS sequence) NM_001322205.1 , NM_001322205.2
    Accession Version NM_001322205.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 2103bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-20
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform NRG-III-beta1a
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK289927.1, EF517295.1, AC103675.2, AC113209.4 and CA429204.1. On Jun 2, 2019 this sequence version replaced NM_001322205.1. Transcript Variant: This variant (NRG-III-beta1a), which uses the type III promoter, lacks several 5' exons but contains an alternate 5' terminal exon, and it thus differs in the 5' UTR and 5' coding region, compared to variant HRG-beta1. The resulting isoform (NRG-III-beta1a, also known as nARIAbeta1a or CRD-NRGbeta1a) has a distinct N-terminus and is longer than isoform HRG-beta1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.218616.1, SRR1803612.233163.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2151358 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    ATGGAGATTT ATTCCCCAGA CATGTCTGAG GTCGCCGCCG AGAGGTCCTC CAGCCCCTCC 
    ACTCAGCTGA GTGCAGACCC ATCTCTTGAT GGGCTTCCGG CAGCAGAAGA CATGCCAGAG
    CCCCAGACTG AAGATGGGAG AACCCCTGGA CTCGTGGGCC TGGCCGTGCC CTGCTGTGCG
    TGCCTAGAAG CTGAGCGCCT GAGAGGTTGC CTCAACTCAG AGAAAATCTG CATTGTCCCC
    ATCCTGGCTT GCCTGGTCAG CCTCTGCCTC TGCATCGCCG GCCTCAAGTG GGTATTTGTG
    GACAAGATCT TTGAATATGA CTCTCCTACT CACCTTGACC CTGGGGGGTT AGGCCAGGAC
    CCTATTATTT CTCTGGACGC AACTGCTGCC TCAGCTGTGT GGGTGTCGTC TGAGGCATAC
    ACTTCACCTG TCTCTAGGGC TCAATCTGAA AGTGAGGTTC AAGTTACAGT GCAAGGTGAC
    AAGGCTGTTG TCTCCTTTGA ACCATCAGCG GCACCGACAC CGAAGAATCG TATTTTTGCC
    TTTTCTTTCT TGCCGTCCAC TGCGCCATCC TTCCCTTCAC CCACCCGGAA CCCTGAGGTG
    AGAACGCCCA AGTCAGCAAC TCAGCCACAA ACAACAGAAA CTAATCTCCA AACTGCTCCT
    AAACTTTCTA CATCTACATC CACCACTGGG ACAAGCCATC TTGTAAAATG TGCGGAGAAG
    GAGAAAACTT TCTGTGTGAA TGGAGGGGAG TGCTTCATGG TGAAAGACCT TTCAAACCCC
    TCGAGATACT TGTGCAAGTG CCCAAATGAG TTTACTGGTG ATCGCTGCCA AAACTACGTA
    ATGGCCAGCT TCTACAAGCA TCTTGGGATT GAATTTATGG AGGCGGAGGA GCTGTACCAG
    AAGAGAGTGC TGACCATAAC CGGCATCTGC ATCGCCCTCC TTGTGGTCGG CATCATGTGT
    GTGGTGGCCT ACTGCAAAAC CAAGAAACAG CGGAAAAAGC TGCATGACCG TCTTCGGCAG
    AGCCTTCGGT CTGAACGAAA CAATATGATG AACATTGCCA ATGGGCCTCA CCATCCTAAC
    CCACCCCCCG AGAATGTCCA GCTGGTGAAT CAATACGTAT CTAAAAACGT CATCTCCAGT
    GAGCATATTG TTGAGAGAGA AGCAGAGACA TCCTTTTCCA CCAGTCACTA TACTTCCACA
    GCCCATCACT CCACTACTGT CACCCAGACT CCTAGCCACA GCTGGAGCAA CGGACACACT
    GAAAGCATCC TTTCCGAAAG CCACTCTGTA ATCGTGATGT CATCCGTAGA AAACAGTAGG
    CACAGCAGCC CAACTGGGGG CCCAAGAGGA CGTCTTAATG GCACAGGAGG CCCTCGTGAA
    TGTAACAGCT TCCTCAGGCA TGCCAGAGAA ACCCCTGATT CCTACCGAGA CTCTCCTCAT
    AGTGAAAGGT ATGTGTCAGC CATGACCACC CCGGCTCGTA TGTCACCTGT AGATTTCCAC
    ACGCCAAGCT CCCCCAAATC GCCCCCTTCG GAAATGTCTC CACCCGTGTC CAGCATGACG
    GTGTCCATGC CTTCCATGGC GGTCAGCCCC TTCATGGAAG AAGAGAGACC TCTACTTCTC
    GTGACACCAC CAAGGCTGCG GGAGAAGAAG TTTGACCATC ACCCTCAGCA GTTCAGCTCC
    TTCCACCACA ACCCCGCGCA TGACAGTAAC AGCCTCCCTG CTAGCCCCTT GAGGATAGTG
    GAGGATGAGG AGTATGAAAC GACCCAAGAG TACGAGCCAG CCCAAGAGCC TGTTAAGAAA
    CTCGCCAATA GCCGGCGGGC CAAAAGAACC AAGCCCAATG GCCACATTGC TAACAGATTG
    GAAGTGGACA GCAACACAAG CTCCCAGAGC AGTAACTCAG AGAGTGAAAC AGAAGATGAA
    AGAGTAGGTG AAGATACGCC TTTCCTGGGC ATACAGAACC CCCTGGCAGC CAGTCTTGAG
    GCAACACCTG CCTTCCGCCT GGCTGACAGC AGGACTAACC CAGCAGGCCG CTTCTCGACA
    CAGGAAGAAA TCCAGGCCAG GCTGTCTAGT GTAATTGCTA ACCAAGACCC TATTGCTGTA
    TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001309134.1
    CDS630..2732
    Translation

    Target ORF information:

    RefSeq Version NM_001322205.2
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant NRG-III-beta1a, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001322205.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    ATGGAGATTT ATTCCCCAGA CATGTCTGAG GTCGCCGCCG AGAGGTCCTC CAGCCCCTCC 
    ACTCAGCTGA GTGCAGACCC ATCTCTTGAT GGGCTTCCGG CAGCAGAAGA CATGCCAGAG
    CCCCAGACTG AAGATGGGAG AACCCCTGGA CTCGTGGGCC TGGCCGTGCC CTGCTGTGCG
    TGCCTAGAAG CTGAGCGCCT GAGAGGTTGC CTCAACTCAG AGAAAATCTG CATTGTCCCC
    ATCCTGGCTT GCCTGGTCAG CCTCTGCCTC TGCATCGCCG GCCTCAAGTG GGTATTTGTG
    GACAAGATCT TTGAATATGA CTCTCCTACT CACCTTGACC CTGGGGGGTT AGGCCAGGAC
    CCTATTATTT CTCTGGACGC AACTGCTGCC TCAGCTGTGT GGGTGTCGTC TGAGGCATAC
    ACTTCACCTG TCTCTAGGGC TCAATCTGAA AGTGAGGTTC AAGTTACAGT GCAAGGTGAC
    AAGGCTGTTG TCTCCTTTGA ACCATCAGCG GCACCGACAC CGAAGAATCG TATTTTTGCC
    TTTTCTTTCT TGCCGTCCAC TGCGCCATCC TTCCCTTCAC CCACCCGGAA CCCTGAGGTG
    AGAACGCCCA AGTCAGCAAC TCAGCCACAA ACAACAGAAA CTAATCTCCA AACTGCTCCT
    AAACTTTCTA CATCTACATC CACCACTGGG ACAAGCCATC TTGTAAAATG TGCGGAGAAG
    GAGAAAACTT TCTGTGTGAA TGGAGGGGAG TGCTTCATGG TGAAAGACCT TTCAAACCCC
    TCGAGATACT TGTGCAAGTG CCCAAATGAG TTTACTGGTG ATCGCTGCCA AAACTACGTA
    ATGGCCAGCT TCTACAAGCA TCTTGGGATT GAATTTATGG AGGCGGAGGA GCTGTACCAG
    AAGAGAGTGC TGACCATAAC CGGCATCTGC ATCGCCCTCC TTGTGGTCGG CATCATGTGT
    GTGGTGGCCT ACTGCAAAAC CAAGAAACAG CGGAAAAAGC TGCATGACCG TCTTCGGCAG
    AGCCTTCGGT CTGAACGAAA CAATATGATG AACATTGCCA ATGGGCCTCA CCATCCTAAC
    CCACCCCCCG AGAATGTCCA GCTGGTGAAT CAATACGTAT CTAAAAACGT CATCTCCAGT
    GAGCATATTG TTGAGAGAGA AGCAGAGACA TCCTTTTCCA CCAGTCACTA TACTTCCACA
    GCCCATCACT CCACTACTGT CACCCAGACT CCTAGCCACA GCTGGAGCAA CGGACACACT
    GAAAGCATCC TTTCCGAAAG CCACTCTGTA ATCGTGATGT CATCCGTAGA AAACAGTAGG
    CACAGCAGCC CAACTGGGGG CCCAAGAGGA CGTCTTAATG GCACAGGAGG CCCTCGTGAA
    TGTAACAGCT TCCTCAGGCA TGCCAGAGAA ACCCCTGATT CCTACCGAGA CTCTCCTCAT
    AGTGAAAGGT ATGTGTCAGC CATGACCACC CCGGCTCGTA TGTCACCTGT AGATTTCCAC
    ACGCCAAGCT CCCCCAAATC GCCCCCTTCG GAAATGTCTC CACCCGTGTC CAGCATGACG
    GTGTCCATGC CTTCCATGGC GGTCAGCCCC TTCATGGAAG AAGAGAGACC TCTACTTCTC
    GTGACACCAC CAAGGCTGCG GGAGAAGAAG TTTGACCATC ACCCTCAGCA GTTCAGCTCC
    TTCCACCACA ACCCCGCGCA TGACAGTAAC AGCCTCCCTG CTAGCCCCTT GAGGATAGTG
    GAGGATGAGG AGTATGAAAC GACCCAAGAG TACGAGCCAG CCCAAGAGCC TGTTAAGAAA
    CTCGCCAATA GCCGGCGGGC CAAAAGAACC AAGCCCAATG GCCACATTGC TAACAGATTG
    GAAGTGGACA GCAACACAAG CTCCCAGAGC AGTAACTCAG AGAGTGAAAC AGAAGATGAA
    AGAGTAGGTG AAGATACGCC TTTCCTGGGC ATACAGAACC CCCTGGCAGC CAGTCTTGAG
    GCAACACCTG CCTTCCGCCT GGCTGACAGC AGGACTAACC CAGCAGGCCG CTTCTCGACA
    CAGGAAGAAA TCCAGGCCAG GCTGTCTAGT GTAATTGCTA ACCAAGACCC TATTGCTGTA
    TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu42056
    Clone ID Related Accession (Same CDS sequence) XM_006716335.3
    Accession Version XM_006716335.3 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1263bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-05
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform X13
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006716335.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGGCCAGCT TCTACAAGCA TCTTGGGATT GAATTTATGG AGGCGGAGGA GCTGTACCAG 
    AAGAGAGTGC TGACCATAAC CGGCATCTGC ATCGCCCTCC TTGTGGTCGG CATCATGTGT
    GTGGTGGCCT ACTGCAAAAC CAAGAAACAG CGGAAAAAGC TGCATGACCG TCTTCGGCAG
    AGCCTTCGGT CTGAACGAAA CAATATGATG AACATTGCCA ATGGGCCTCA CCATCCTAAC
    CCACCCCCCG AGAATGTCCA GCTGGTGAAT CAATACGTAT CTAAAAACGT CATCTCCAGT
    GAGCATATTG TTGAGAGAGA AGCAGAGACA TCCTTTTCCA CCAGTCACTA TACTTCCACA
    GCCCATCACT CCACTACTGT CACCCAGACT CCTAGCCACA GCTGGAGCAA CGGACACACT
    GAAAGCATCC TTTCCGAAAG CCACTCTGTA ATCGTGATGT CATCCGTAGA AAACAGTAGG
    CACAGCAGCC CAACTGGGGG CCCAAGAGGA CGTCTTAATG GCACAGGAGG CCCTCGTGAA
    TGTAACAGCT TCCTCAGGCA TGCCAGAGAA ACCCCTGATT CCTACCGAGA CTCTCCTCAT
    AGTGAAAGGT ATGTGTCAGC CATGACCACC CCGGCTCGTA TGTCACCTGT AGATTTCCAC
    ACGCCAAGCT CCCCCAAATC GCCCCCTTCG GAAATGTCTC CACCCGTGTC CAGCATGACG
    GTGTCCATGC CTTCCATGGC GGTCAGCCCC TTCATGGAAG AAGAGAGACC TCTACTTCTC
    GTGACACCAC CAAGGCTGCG GGAGAAGAAG TTTGACCATC ACCCTCAGCA GTTCAGCTCC
    TTCCACCACA ACCCCGCGCA TGACAGTAAC AGCCTCCCTG CTAGCCCCTT GAGGATAGTG
    GAGGATGAGG AGTATGAAAC GACCCAAGAG TACGAGCCAG CCCAAGAGCC TGTTAAGAAA
    CTCGCCAATA GCCGGCGGGC CAAAAGAACC AAGCCCAATG GCCACATTGC TAACAGATTG
    GAAGTGGACA GCAACACAAG CTCCCAGAGC AGTAACTCAG AGAGTGAAAC AGAAGATGAA
    AGAGTAGGTG AAGATACGCC TTTCCTGGGC ATACAGAACC CCCTGGCAGC CAGTCTTGAG
    GCAACACCTG CCTTCCGCCT GGCTGACAGC AGGACTAACC CAGCAGGCCG CTTCTCGACA
    CAGGAAGAAA TCCAGGCCAG GCTGTCTAGT GTAATTGCTA ACCAAGACCC TATTGCTGTA
    TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_006716398.1
    CDS178..1440
    Translation

    Target ORF information:

    RefSeq Version XM_006716335.3
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant X13, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_006716335.3

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGGCCAGCT TCTACAAGCA TCTTGGGATT GAATTTATGG AGGCGGAGGA GCTGTACCAG 
    AAGAGAGTGC TGACCATAAC CGGCATCTGC ATCGCCCTCC TTGTGGTCGG CATCATGTGT
    GTGGTGGCCT ACTGCAAAAC CAAGAAACAG CGGAAAAAGC TGCATGACCG TCTTCGGCAG
    AGCCTTCGGT CTGAACGAAA CAATATGATG AACATTGCCA ATGGGCCTCA CCATCCTAAC
    CCACCCCCCG AGAATGTCCA GCTGGTGAAT CAATACGTAT CTAAAAACGT CATCTCCAGT
    GAGCATATTG TTGAGAGAGA AGCAGAGACA TCCTTTTCCA CCAGTCACTA TACTTCCACA
    GCCCATCACT CCACTACTGT CACCCAGACT CCTAGCCACA GCTGGAGCAA CGGACACACT
    GAAAGCATCC TTTCCGAAAG CCACTCTGTA ATCGTGATGT CATCCGTAGA AAACAGTAGG
    CACAGCAGCC CAACTGGGGG CCCAAGAGGA CGTCTTAATG GCACAGGAGG CCCTCGTGAA
    TGTAACAGCT TCCTCAGGCA TGCCAGAGAA ACCCCTGATT CCTACCGAGA CTCTCCTCAT
    AGTGAAAGGT ATGTGTCAGC CATGACCACC CCGGCTCGTA TGTCACCTGT AGATTTCCAC
    ACGCCAAGCT CCCCCAAATC GCCCCCTTCG GAAATGTCTC CACCCGTGTC CAGCATGACG
    GTGTCCATGC CTTCCATGGC GGTCAGCCCC TTCATGGAAG AAGAGAGACC TCTACTTCTC
    GTGACACCAC CAAGGCTGCG GGAGAAGAAG TTTGACCATC ACCCTCAGCA GTTCAGCTCC
    TTCCACCACA ACCCCGCGCA TGACAGTAAC AGCCTCCCTG CTAGCCCCTT GAGGATAGTG
    GAGGATGAGG AGTATGAAAC GACCCAAGAG TACGAGCCAG CCCAAGAGCC TGTTAAGAAA
    CTCGCCAATA GCCGGCGGGC CAAAAGAACC AAGCCCAATG GCCACATTGC TAACAGATTG
    GAAGTGGACA GCAACACAAG CTCCCAGAGC AGTAACTCAG AGAGTGAAAC AGAAGATGAA
    AGAGTAGGTG AAGATACGCC TTTCCTGGGC ATACAGAACC CCCTGGCAGC CAGTCTTGAG
    GCAACACCTG CCTTCCGCCT GGCTGACAGC AGGACTAACC CAGCAGGCCG CTTCTCGACA
    CAGGAAGAAA TCCAGGCCAG GCTGTCTAGT GTAATTGCTA ACCAAGACCC TATTGCTGTA
    TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu102675
    Clone ID Related Accession (Same CDS sequence) NM_001322202.2 , NM_001322202.1 , NM_001322201.1 , NM_001322201.2
    Accession Version NM_001322202.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1149bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-20
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform a
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from GQ983557.1, EF372277.1, AC103675.2, AC113209.4 and CA429204.1. On Jun 2, 2019 this sequence version replaced NM_001322202.1. Transcript Variant: This variant (fetal-c-IV-2), which uses the type IV promoter, contains an alternate 5' terminal exon and lacks four internal exons, and it thus differs in the 5' UTR and initiates translation from a downstream in-frame start codon, compared to variant 1. The resulting isoform (a) is shorter at the N-terminus, compared to isoform HRG-beta1. Both variants fetal-a-IV-1 and fetal-c-IV-2 encode isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGTGTGTGG TGGCCTACTG CAAAACCAAG AAACAGCGGA AAAAGCTGCA TGACCGTCTT 
    CGGCAGAGCC TTCGGTCTGA ACGAAACAAT ATGATGAACA TTGCCAATGG GCCTCACCAT
    CCTAACCCAC CCCCCGAGAA TGTCCAGCTG GTGAATCAAT ACGTATCTAA AAACGTCATC
    TCCAGTGAGC ATATTGTTGA GAGAGAAGCA GAGACATCCT TTTCCACCAG TCACTATACT
    TCCACAGCCC ATCACTCCAC TACTGTCACC CAGACTCCTA GCCACAGCTG GAGCAACGGA
    CACACTGAAA GCATCCTTTC CGAAAGCCAC TCTGTAATCG TGATGTCATC CGTAGAAAAC
    AGTAGGCACA GCAGCCCAAC TGGGGGCCCA AGAGGACGTC TTAATGGCAC AGGAGGCCCT
    CGTGAATGTA ACAGCTTCCT CAGGCATGCC AGAGAAACCC CTGATTCCTA CCGAGACTCT
    CCTCATAGTG AAAGGTATGT GTCAGCCATG ACCACCCCGG CTCGTATGTC ACCTGTAGAT
    TTCCACACGC CAAGCTCCCC CAAATCGCCC CCTTCGGAAA TGTCTCCACC CGTGTCCAGC
    ATGACGGTGT CCATGCCTTC CATGGCGGTC AGCCCCTTCA TGGAAGAAGA GAGACCTCTA
    CTTCTCGTGA CACCACCAAG GCTGCGGGAG AAGAAGTTTG ACCATCACCC TCAGCAGTTC
    AGCTCCTTCC ACCACAACCC CGCGCATGAC AGTAACAGCC TCCCTGCTAG CCCCTTGAGG
    ATAGTGGAGG ATGAGGAGTA TGAAACGACC CAAGAGTACG AGCCAGCCCA AGAGCCTGTT
    AAGAAACTCG CCAATAGCCG GCGGGCCAAA AGAACCAAGC CCAATGGCCA CATTGCTAAC
    AGATTGGAAG TGGACAGCAA CACAAGCTCC CAGAGCAGTA ACTCAGAGAG TGAAACAGAA
    GATGAAAGAG TAGGTGAAGA TACGCCTTTC CTGGGCATAC AGAACCCCCT GGCAGCCAGT
    CTTGAGGCAA CACCTGCCTT CCGCCTGGCT GACAGCAGGA CTAACCCAGC AGGCCGCTTC
    TCGACACAGG AAGAAATCCA GGCCAGGCTG TCTAGTGTAA TTGCTAACCA AGACCCTATT
    GCTGTATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001309131.1
    CDS692..1840
    Translation

    Target ORF information:

    RefSeq Version NM_001322202.2
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant fetal-c-IV-2, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001322202.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGTGTGTGG TGGCCTACTG CAAAACCAAG AAACAGCGGA AAAAGCTGCA TGACCGTCTT 
    CGGCAGAGCC TTCGGTCTGA ACGAAACAAT ATGATGAACA TTGCCAATGG GCCTCACCAT
    CCTAACCCAC CCCCCGAGAA TGTCCAGCTG GTGAATCAAT ACGTATCTAA AAACGTCATC
    TCCAGTGAGC ATATTGTTGA GAGAGAAGCA GAGACATCCT TTTCCACCAG TCACTATACT
    TCCACAGCCC ATCACTCCAC TACTGTCACC CAGACTCCTA GCCACAGCTG GAGCAACGGA
    CACACTGAAA GCATCCTTTC CGAAAGCCAC TCTGTAATCG TGATGTCATC CGTAGAAAAC
    AGTAGGCACA GCAGCCCAAC TGGGGGCCCA AGAGGACGTC TTAATGGCAC AGGAGGCCCT
    CGTGAATGTA ACAGCTTCCT CAGGCATGCC AGAGAAACCC CTGATTCCTA CCGAGACTCT
    CCTCATAGTG AAAGGTATGT GTCAGCCATG ACCACCCCGG CTCGTATGTC ACCTGTAGAT
    TTCCACACGC CAAGCTCCCC CAAATCGCCC CCTTCGGAAA TGTCTCCACC CGTGTCCAGC
    ATGACGGTGT CCATGCCTTC CATGGCGGTC AGCCCCTTCA TGGAAGAAGA GAGACCTCTA
    CTTCTCGTGA CACCACCAAG GCTGCGGGAG AAGAAGTTTG ACCATCACCC TCAGCAGTTC
    AGCTCCTTCC ACCACAACCC CGCGCATGAC AGTAACAGCC TCCCTGCTAG CCCCTTGAGG
    ATAGTGGAGG ATGAGGAGTA TGAAACGACC CAAGAGTACG AGCCAGCCCA AGAGCCTGTT
    AAGAAACTCG CCAATAGCCG GCGGGCCAAA AGAACCAAGC CCAATGGCCA CATTGCTAAC
    AGATTGGAAG TGGACAGCAA CACAAGCTCC CAGAGCAGTA ACTCAGAGAG TGAAACAGAA
    GATGAAAGAG TAGGTGAAGA TACGCCTTTC CTGGGCATAC AGAACCCCCT GGCAGCCAGT
    CTTGAGGCAA CACCTGCCTT CCGCCTGGCT GACAGCAGGA CTAACCCAGC AGGCCGCTTC
    TCGACACAGG AAGAAATCCA GGCCAGGCTG TCTAGTGTAA TTGCTAACCA AGACCCTATT
    GCTGTATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu102675
    Clone ID Related Accession (Same CDS sequence) NM_001322202.2 , NM_001322202.1 , NM_001322201.1 , NM_001322201.2
    Accession Version NM_001322202.1 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1149bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2018-12-22
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform a
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from GQ983557.1, EF372277.1, AC103675.2, AC113209.4 and CA429204.1. Transcript Variant: This variant (fetal-c-IV-2), which uses the type IV promoter, contains an alternate 5' terminal exon and lacks four internal exons, and it thus differs in the 5' UTR and initiates translation from a downstream in-frame start codon, compared to variant 1. The resulting isoform (a) is shorter at the N-terminus, compared to isoform HRG-beta1. Both variants fetal-a-IV-1 and fetal-c-IV-2 encode isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EF372277.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGTGTGTGG TGGCCTACTG CAAAACCAAG AAACAGCGGA AAAAGCTGCA TGACCGTCTT 
    CGGCAGAGCC TTCGGTCTGA ACGAAACAAT ATGATGAACA TTGCCAATGG GCCTCACCAT
    CCTAACCCAC CCCCCGAGAA TGTCCAGCTG GTGAATCAAT ACGTATCTAA AAACGTCATC
    TCCAGTGAGC ATATTGTTGA GAGAGAAGCA GAGACATCCT TTTCCACCAG TCACTATACT
    TCCACAGCCC ATCACTCCAC TACTGTCACC CAGACTCCTA GCCACAGCTG GAGCAACGGA
    CACACTGAAA GCATCCTTTC CGAAAGCCAC TCTGTAATCG TGATGTCATC CGTAGAAAAC
    AGTAGGCACA GCAGCCCAAC TGGGGGCCCA AGAGGACGTC TTAATGGCAC AGGAGGCCCT
    CGTGAATGTA ACAGCTTCCT CAGGCATGCC AGAGAAACCC CTGATTCCTA CCGAGACTCT
    CCTCATAGTG AAAGGTATGT GTCAGCCATG ACCACCCCGG CTCGTATGTC ACCTGTAGAT
    TTCCACACGC CAAGCTCCCC CAAATCGCCC CCTTCGGAAA TGTCTCCACC CGTGTCCAGC
    ATGACGGTGT CCATGCCTTC CATGGCGGTC AGCCCCTTCA TGGAAGAAGA GAGACCTCTA
    CTTCTCGTGA CACCACCAAG GCTGCGGGAG AAGAAGTTTG ACCATCACCC TCAGCAGTTC
    AGCTCCTTCC ACCACAACCC CGCGCATGAC AGTAACAGCC TCCCTGCTAG CCCCTTGAGG
    ATAGTGGAGG ATGAGGAGTA TGAAACGACC CAAGAGTACG AGCCAGCCCA AGAGCCTGTT
    AAGAAACTCG CCAATAGCCG GCGGGCCAAA AGAACCAAGC CCAATGGCCA CATTGCTAAC
    AGATTGGAAG TGGACAGCAA CACAAGCTCC CAGAGCAGTA ACTCAGAGAG TGAAACAGAA
    GATGAAAGAG TAGGTGAAGA TACGCCTTTC CTGGGCATAC AGAACCCCCT GGCAGCCAGT
    CTTGAGGCAA CACCTGCCTT CCGCCTGGCT GACAGCAGGA CTAACCCAGC AGGCCGCTTC
    TCGACACAGG AAGAAATCCA GGCCAGGCTG TCTAGTGTAA TTGCTAACCA AGACCCTATT
    GCTGTATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001309131.1
    CDS715..1863
    Translation

    Target ORF information:

    RefSeq Version NM_001322202.1
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant fetal-c-IV-2, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001322202.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGTGTGTGG TGGCCTACTG CAAAACCAAG AAACAGCGGA AAAAGCTGCA TGACCGTCTT 
    CGGCAGAGCC TTCGGTCTGA ACGAAACAAT ATGATGAACA TTGCCAATGG GCCTCACCAT
    CCTAACCCAC CCCCCGAGAA TGTCCAGCTG GTGAATCAAT ACGTATCTAA AAACGTCATC
    TCCAGTGAGC ATATTGTTGA GAGAGAAGCA GAGACATCCT TTTCCACCAG TCACTATACT
    TCCACAGCCC ATCACTCCAC TACTGTCACC CAGACTCCTA GCCACAGCTG GAGCAACGGA
    CACACTGAAA GCATCCTTTC CGAAAGCCAC TCTGTAATCG TGATGTCATC CGTAGAAAAC
    AGTAGGCACA GCAGCCCAAC TGGGGGCCCA AGAGGACGTC TTAATGGCAC AGGAGGCCCT
    CGTGAATGTA ACAGCTTCCT CAGGCATGCC AGAGAAACCC CTGATTCCTA CCGAGACTCT
    CCTCATAGTG AAAGGTATGT GTCAGCCATG ACCACCCCGG CTCGTATGTC ACCTGTAGAT
    TTCCACACGC CAAGCTCCCC CAAATCGCCC CCTTCGGAAA TGTCTCCACC CGTGTCCAGC
    ATGACGGTGT CCATGCCTTC CATGGCGGTC AGCCCCTTCA TGGAAGAAGA GAGACCTCTA
    CTTCTCGTGA CACCACCAAG GCTGCGGGAG AAGAAGTTTG ACCATCACCC TCAGCAGTTC
    AGCTCCTTCC ACCACAACCC CGCGCATGAC AGTAACAGCC TCCCTGCTAG CCCCTTGAGG
    ATAGTGGAGG ATGAGGAGTA TGAAACGACC CAAGAGTACG AGCCAGCCCA AGAGCCTGTT
    AAGAAACTCG CCAATAGCCG GCGGGCCAAA AGAACCAAGC CCAATGGCCA CATTGCTAAC
    AGATTGGAAG TGGACAGCAA CACAAGCTCC CAGAGCAGTA ACTCAGAGAG TGAAACAGAA
    GATGAAAGAG TAGGTGAAGA TACGCCTTTC CTGGGCATAC AGAACCCCCT GGCAGCCAGT
    CTTGAGGCAA CACCTGCCTT CCGCCTGGCT GACAGCAGGA CTAACCCAGC AGGCCGCTTC
    TCGACACAGG AAGAAATCCA GGCCAGGCTG TCTAGTGTAA TTGCTAACCA AGACCCTATT
    GCTGTATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu102675
    Clone ID Related Accession (Same CDS sequence) NM_001322202.2 , NM_001322202.1 , NM_001322201.1 , NM_001322201.2
    Accession Version NM_001322201.1 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1149bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2018-12-22
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform a
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from GQ983557.1, EF372275.1, AC083977.5, AC103675.2, AC113209.4 and CA429204.1. Transcript Variant: This variant (fetal-a-IV-1), which uses the type IV promoter, contains an alternate 5' terminal exon and lacks three internal exons, and it thus differs in the 5' UTR and initiates translation from a downstream in-frame start codon, compared to variant HRG-beta1. The resulting isoform (a) is shorter at the N-terminus, compared to isoform HRG-beta1. Both variants fetal-a-IV-1 and fetal-c-IV-2 encode isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EF372275.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGTGTGTGG TGGCCTACTG CAAAACCAAG AAACAGCGGA AAAAGCTGCA TGACCGTCTT 
    CGGCAGAGCC TTCGGTCTGA ACGAAACAAT ATGATGAACA TTGCCAATGG GCCTCACCAT
    CCTAACCCAC CCCCCGAGAA TGTCCAGCTG GTGAATCAAT ACGTATCTAA AAACGTCATC
    TCCAGTGAGC ATATTGTTGA GAGAGAAGCA GAGACATCCT TTTCCACCAG TCACTATACT
    TCCACAGCCC ATCACTCCAC TACTGTCACC CAGACTCCTA GCCACAGCTG GAGCAACGGA
    CACACTGAAA GCATCCTTTC CGAAAGCCAC TCTGTAATCG TGATGTCATC CGTAGAAAAC
    AGTAGGCACA GCAGCCCAAC TGGGGGCCCA AGAGGACGTC TTAATGGCAC AGGAGGCCCT
    CGTGAATGTA ACAGCTTCCT CAGGCATGCC AGAGAAACCC CTGATTCCTA CCGAGACTCT
    CCTCATAGTG AAAGGTATGT GTCAGCCATG ACCACCCCGG CTCGTATGTC ACCTGTAGAT
    TTCCACACGC CAAGCTCCCC CAAATCGCCC CCTTCGGAAA TGTCTCCACC CGTGTCCAGC
    ATGACGGTGT CCATGCCTTC CATGGCGGTC AGCCCCTTCA TGGAAGAAGA GAGACCTCTA
    CTTCTCGTGA CACCACCAAG GCTGCGGGAG AAGAAGTTTG ACCATCACCC TCAGCAGTTC
    AGCTCCTTCC ACCACAACCC CGCGCATGAC AGTAACAGCC TCCCTGCTAG CCCCTTGAGG
    ATAGTGGAGG ATGAGGAGTA TGAAACGACC CAAGAGTACG AGCCAGCCCA AGAGCCTGTT
    AAGAAACTCG CCAATAGCCG GCGGGCCAAA AGAACCAAGC CCAATGGCCA CATTGCTAAC
    AGATTGGAAG TGGACAGCAA CACAAGCTCC CAGAGCAGTA ACTCAGAGAG TGAAACAGAA
    GATGAAAGAG TAGGTGAAGA TACGCCTTTC CTGGGCATAC AGAACCCCCT GGCAGCCAGT
    CTTGAGGCAA CACCTGCCTT CCGCCTGGCT GACAGCAGGA CTAACCCAGC AGGCCGCTTC
    TCGACACAGG AAGAAATCCA GGCCAGGCTG TCTAGTGTAA TTGCTAACCA AGACCCTATT
    GCTGTATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001309130.1
    CDS766..1914
    Translation

    Target ORF information:

    RefSeq Version NM_001322201.1
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant fetal-a-IV-1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001322201.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGTGTGTGG TGGCCTACTG CAAAACCAAG AAACAGCGGA AAAAGCTGCA TGACCGTCTT 
    CGGCAGAGCC TTCGGTCTGA ACGAAACAAT ATGATGAACA TTGCCAATGG GCCTCACCAT
    CCTAACCCAC CCCCCGAGAA TGTCCAGCTG GTGAATCAAT ACGTATCTAA AAACGTCATC
    TCCAGTGAGC ATATTGTTGA GAGAGAAGCA GAGACATCCT TTTCCACCAG TCACTATACT
    TCCACAGCCC ATCACTCCAC TACTGTCACC CAGACTCCTA GCCACAGCTG GAGCAACGGA
    CACACTGAAA GCATCCTTTC CGAAAGCCAC TCTGTAATCG TGATGTCATC CGTAGAAAAC
    AGTAGGCACA GCAGCCCAAC TGGGGGCCCA AGAGGACGTC TTAATGGCAC AGGAGGCCCT
    CGTGAATGTA ACAGCTTCCT CAGGCATGCC AGAGAAACCC CTGATTCCTA CCGAGACTCT
    CCTCATAGTG AAAGGTATGT GTCAGCCATG ACCACCCCGG CTCGTATGTC ACCTGTAGAT
    TTCCACACGC CAAGCTCCCC CAAATCGCCC CCTTCGGAAA TGTCTCCACC CGTGTCCAGC
    ATGACGGTGT CCATGCCTTC CATGGCGGTC AGCCCCTTCA TGGAAGAAGA GAGACCTCTA
    CTTCTCGTGA CACCACCAAG GCTGCGGGAG AAGAAGTTTG ACCATCACCC TCAGCAGTTC
    AGCTCCTTCC ACCACAACCC CGCGCATGAC AGTAACAGCC TCCCTGCTAG CCCCTTGAGG
    ATAGTGGAGG ATGAGGAGTA TGAAACGACC CAAGAGTACG AGCCAGCCCA AGAGCCTGTT
    AAGAAACTCG CCAATAGCCG GCGGGCCAAA AGAACCAAGC CCAATGGCCA CATTGCTAAC
    AGATTGGAAG TGGACAGCAA CACAAGCTCC CAGAGCAGTA ACTCAGAGAG TGAAACAGAA
    GATGAAAGAG TAGGTGAAGA TACGCCTTTC CTGGGCATAC AGAACCCCCT GGCAGCCAGT
    CTTGAGGCAA CACCTGCCTT CCGCCTGGCT GACAGCAGGA CTAACCCAGC AGGCCGCTTC
    TCGACACAGG AAGAAATCCA GGCCAGGCTG TCTAGTGTAA TTGCTAACCA AGACCCTATT
    GCTGTATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu102675
    Clone ID Related Accession (Same CDS sequence) NM_001322202.2 , NM_001322202.1 , NM_001322201.1 , NM_001322201.2
    Accession Version NM_001322201.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1149bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-20
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform a
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from GQ983557.1, EF372275.1, AC083977.5, AC103675.2, AC113209.4 and CA429204.1. On Jun 2, 2019 this sequence version replaced NM_001322201.1. Transcript Variant: This variant (fetal-a-IV-1), which uses the type IV promoter, contains an alternate 5' terminal exon and lacks three internal exons, and it thus differs in the 5' UTR and initiates translation from a downstream in-frame start codon, compared to variant HRG-beta1. The resulting isoform (a) is shorter at the N-terminus, compared to isoform HRG-beta1. Both variants fetal-a-IV-1 and fetal-c-IV-2 encode isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGTGTGTGG TGGCCTACTG CAAAACCAAG AAACAGCGGA AAAAGCTGCA TGACCGTCTT 
    CGGCAGAGCC TTCGGTCTGA ACGAAACAAT ATGATGAACA TTGCCAATGG GCCTCACCAT
    CCTAACCCAC CCCCCGAGAA TGTCCAGCTG GTGAATCAAT ACGTATCTAA AAACGTCATC
    TCCAGTGAGC ATATTGTTGA GAGAGAAGCA GAGACATCCT TTTCCACCAG TCACTATACT
    TCCACAGCCC ATCACTCCAC TACTGTCACC CAGACTCCTA GCCACAGCTG GAGCAACGGA
    CACACTGAAA GCATCCTTTC CGAAAGCCAC TCTGTAATCG TGATGTCATC CGTAGAAAAC
    AGTAGGCACA GCAGCCCAAC TGGGGGCCCA AGAGGACGTC TTAATGGCAC AGGAGGCCCT
    CGTGAATGTA ACAGCTTCCT CAGGCATGCC AGAGAAACCC CTGATTCCTA CCGAGACTCT
    CCTCATAGTG AAAGGTATGT GTCAGCCATG ACCACCCCGG CTCGTATGTC ACCTGTAGAT
    TTCCACACGC CAAGCTCCCC CAAATCGCCC CCTTCGGAAA TGTCTCCACC CGTGTCCAGC
    ATGACGGTGT CCATGCCTTC CATGGCGGTC AGCCCCTTCA TGGAAGAAGA GAGACCTCTA
    CTTCTCGTGA CACCACCAAG GCTGCGGGAG AAGAAGTTTG ACCATCACCC TCAGCAGTTC
    AGCTCCTTCC ACCACAACCC CGCGCATGAC AGTAACAGCC TCCCTGCTAG CCCCTTGAGG
    ATAGTGGAGG ATGAGGAGTA TGAAACGACC CAAGAGTACG AGCCAGCCCA AGAGCCTGTT
    AAGAAACTCG CCAATAGCCG GCGGGCCAAA AGAACCAAGC CCAATGGCCA CATTGCTAAC
    AGATTGGAAG TGGACAGCAA CACAAGCTCC CAGAGCAGTA ACTCAGAGAG TGAAACAGAA
    GATGAAAGAG TAGGTGAAGA TACGCCTTTC CTGGGCATAC AGAACCCCCT GGCAGCCAGT
    CTTGAGGCAA CACCTGCCTT CCGCCTGGCT GACAGCAGGA CTAACCCAGC AGGCCGCTTC
    TCGACACAGG AAGAAATCCA GGCCAGGCTG TCTAGTGTAA TTGCTAACCA AGACCCTATT
    GCTGTATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001309130.1
    CDS743..1891
    Translation

    Target ORF information:

    RefSeq Version NM_001322201.2
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant fetal-a-IV-1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001322201.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGTGTGTGG TGGCCTACTG CAAAACCAAG AAACAGCGGA AAAAGCTGCA TGACCGTCTT 
    CGGCAGAGCC TTCGGTCTGA ACGAAACAAT ATGATGAACA TTGCCAATGG GCCTCACCAT
    CCTAACCCAC CCCCCGAGAA TGTCCAGCTG GTGAATCAAT ACGTATCTAA AAACGTCATC
    TCCAGTGAGC ATATTGTTGA GAGAGAAGCA GAGACATCCT TTTCCACCAG TCACTATACT
    TCCACAGCCC ATCACTCCAC TACTGTCACC CAGACTCCTA GCCACAGCTG GAGCAACGGA
    CACACTGAAA GCATCCTTTC CGAAAGCCAC TCTGTAATCG TGATGTCATC CGTAGAAAAC
    AGTAGGCACA GCAGCCCAAC TGGGGGCCCA AGAGGACGTC TTAATGGCAC AGGAGGCCCT
    CGTGAATGTA ACAGCTTCCT CAGGCATGCC AGAGAAACCC CTGATTCCTA CCGAGACTCT
    CCTCATAGTG AAAGGTATGT GTCAGCCATG ACCACCCCGG CTCGTATGTC ACCTGTAGAT
    TTCCACACGC CAAGCTCCCC CAAATCGCCC CCTTCGGAAA TGTCTCCACC CGTGTCCAGC
    ATGACGGTGT CCATGCCTTC CATGGCGGTC AGCCCCTTCA TGGAAGAAGA GAGACCTCTA
    CTTCTCGTGA CACCACCAAG GCTGCGGGAG AAGAAGTTTG ACCATCACCC TCAGCAGTTC
    AGCTCCTTCC ACCACAACCC CGCGCATGAC AGTAACAGCC TCCCTGCTAG CCCCTTGAGG
    ATAGTGGAGG ATGAGGAGTA TGAAACGACC CAAGAGTACG AGCCAGCCCA AGAGCCTGTT
    AAGAAACTCG CCAATAGCCG GCGGGCCAAA AGAACCAAGC CCAATGGCCA CATTGCTAAC
    AGATTGGAAG TGGACAGCAA CACAAGCTCC CAGAGCAGTA ACTCAGAGAG TGAAACAGAA
    GATGAAAGAG TAGGTGAAGA TACGCCTTTC CTGGGCATAC AGAACCCCCT GGCAGCCAGT
    CTTGAGGCAA CACCTGCCTT CCGCCTGGCT GACAGCAGGA CTAACCCAGC AGGCCGCTTC
    TCGACACAGG AAGAAATCCA GGCCAGGCTG TCTAGTGTAA TTGCTAACCA AGACCCTATT
    GCTGTATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu28420
    Clone ID Related Accession (Same CDS sequence) NM_001160005.1
    Accession Version NM_001160005.1 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 624bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-19
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform HRG-beta3b
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC083977.5, EU359055.1 and M94168.1. Transcript Variant: This variant (HRG-beta3b), which uses the type I promoter, lacks two internal in-frame exons and multiple 3' exons, but contains an alternate 3' terminal exon and thus differs in the 3' coding region and 3' UTR, compared to variant HRG-beta1. The resulting isoform (HRG-beta3b, also known as HRG-beta 3 protein isoform) lacks an internal segment, has a distinct C-terminus, and is shorter than isoform HRG-beta1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EU359055.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145122, SAMEA2148874 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG CTACATCTAC ATCCACCACT
    GGGACAAGCC ATCTTGTAAA ATGTGCGGAG AAGGAGAAAA CTTTCTGTGT GAATGGAGGG
    GAGTGCTTCA TGGTGAAAGA CCTTTCAAAC CCCTCGAGAT ACTTGTGCAA GTGCCCAAAT
    GAGTTTACTG GTGATCGCTG CCAAAACTAC GTAATGGCCA GCTTCTACAG TACGTCCACT
    CCCTTTCTGT CTCTGCCTGA ATAG

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001153477.1
    CDS518..1141
    Translation

    Target ORF information:

    RefSeq Version NM_001160005.1
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta3b, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001160005.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG CTACATCTAC ATCCACCACT
    GGGACAAGCC ATCTTGTAAA ATGTGCGGAG AAGGAGAAAA CTTTCTGTGT GAATGGAGGG
    GAGTGCTTCA TGGTGAAAGA CCTTTCAAAC CCCTCGAGAT ACTTGTGCAA GTGCCCAAAT
    GAGTTTACTG GTGATCGCTG CCAAAACTAC GTAATGGCCA GCTTCTACAG TACGTCCACT
    CCCTTTCTGT CTCTGCCTGA ATAG

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu28425
    Clone ID Related Accession (Same CDS sequence) NM_004495.4 , NM_004495.3
    Accession Version NM_004495.4 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 636bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2020-01-04
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform HRG-gamma
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC083977.5, BC144446.1 and AC103675.2. On Jun 2, 2019 this sequence version replaced NM_004495.3. Transcript Variant: This variant (HRG-gamma), which uses the type I promoter, lacks multiple 3' exons but contains an alternate 3' terminal exon that results in an early stop codon, compared to variant HRG-beta1. The resulting isoform (HRG-gamma) is shorter at the C-terminus, compared to isoform HRG-beta1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF026146.1, DR005461.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_004486.2
    CDS417..1052
    Translation

    Target ORF information:

    RefSeq Version NM_004495.4
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-gamma, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_004495.4

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu28425
    Clone ID Related Accession (Same CDS sequence) NM_004495.4 , NM_004495.3
    Accession Version NM_004495.3 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 636bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-02-20
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform HRG-gamma
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC083977.5, BC144446.1 and AC103675.2. On May 13, 2009 this sequence version replaced NM_004495.2. Transcript Variant: This variant (HRG-gamma), which uses the type I promoter, lacks multiple 3' exons but contains an alternate 3' terminal exon that results in an early stop codon, compared to variant HRG-beta1. The resulting isoform (HRG-gamma) is shorter at the C-terminus, compared to isoform HRG-beta1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF026146.1, DR005461.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_004486.2
    CDS518..1153
    Translation

    Target ORF information:

    RefSeq Version NM_004495.3
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-gamma, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_004495.3

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu28427
    Clone ID Related Accession (Same CDS sequence) NM_013959.3
    Accession Version NM_013959.3 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 891bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-19
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform SMDF
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK289927.1 and M94168.1. On May 13, 2009 this sequence version replaced NM_013959.2. Transcript Variant: This variant (SMDF), which uses the type III promoter, is expressed mainly in the nervous system. It lacks multiple 5' and 3' exons but has alternate 5' and 3' terminal exons, and it thus differs in the 5' and 3' coding regions and in both UTRs, compared to variant HRG-beta1. The resulting isoform (SMDF, also known as NRG-III-beta3) has distinct N- and C-termini and is shorter than isoform HRG-beta1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK289927.1, SRR1660809.113570.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGGAGATTT ATTCCCCAGA CATGTCTGAG GTCGCCGCCG AGAGGTCCTC CAGCCCCTCC 
    ACTCAGCTGA GTGCAGACCC ATCTCTTGAT GGGCTTCCGG CAGCAGAAGA CATGCCAGAG
    CCCCAGACTG AAGATGGGAG AACCCCTGGA CTCGTGGGCC TGGCCGTGCC CTGCTGTGCG
    TGCCTAGAAG CTGAGCGCCT GAGAGGTTGC CTCAACTCAG AGAAAATCTG CATTGTCCCC
    ATCCTGGCTT GCCTGGTCAG CCTCTGCCTC TGCATCGCCG GCCTCAAGTG GGTATTTGTG
    GACAAGATCT TTGAATATGA CTCTCCTACT CACCTTGACC CTGGGGGGTT AGGCCAGGAC
    CCTATTATTT CTCTGGACGC AACTGCTGCC TCAGCTGTGT GGGTGTCGTC TGAGGCATAC
    ACTTCACCTG TCTCTAGGGC TCAATCTGAA AGTGAGGTTC AAGTTACAGT GCAAGGTGAC
    AAGGCTGTTG TCTCCTTTGA ACCATCAGCG GCACCGACAC CGAAGAATCG TATTTTTGCC
    TTTTCTTTCT TGCCGTCCAC TGCGCCATCC TTCCCTTCAC CCACCCGGAA CCCTGAGGTG
    AGAACGCCCA AGTCAGCAAC TCAGCCACAA ACAACAGAAA CTAATCTCCA AACTGCTCCT
    AAACTTTCTA CATCTACATC CACCACTGGG ACAAGCCATC TTGTAAAATG TGCGGAGAAG
    GAGAAAACTT TCTGTGTGAA TGGAGGGGAG TGCTTCATGG TGAAAGACCT TTCAAACCCC
    TCGAGATACT TGTGCAAGTG CCCAAATGAG TTTACTGGTG ATCGCTGCCA AAACTACGTA
    ATGGCCAGCT TCTACAGTAC GTCCACTCCC TTTCTGTCTC TGCCTGAATA G

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_039253.1
    CDS987..1877
    Translation

    Target ORF information:

    RefSeq Version NM_013959.3
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant SMDF, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_013959.3

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGGAGATTT ATTCCCCAGA CATGTCTGAG GTCGCCGCCG AGAGGTCCTC CAGCCCCTCC 
    ACTCAGCTGA GTGCAGACCC ATCTCTTGAT GGGCTTCCGG CAGCAGAAGA CATGCCAGAG
    CCCCAGACTG AAGATGGGAG AACCCCTGGA CTCGTGGGCC TGGCCGTGCC CTGCTGTGCG
    TGCCTAGAAG CTGAGCGCCT GAGAGGTTGC CTCAACTCAG AGAAAATCTG CATTGTCCCC
    ATCCTGGCTT GCCTGGTCAG CCTCTGCCTC TGCATCGCCG GCCTCAAGTG GGTATTTGTG
    GACAAGATCT TTGAATATGA CTCTCCTACT CACCTTGACC CTGGGGGGTT AGGCCAGGAC
    CCTATTATTT CTCTGGACGC AACTGCTGCC TCAGCTGTGT GGGTGTCGTC TGAGGCATAC
    ACTTCACCTG TCTCTAGGGC TCAATCTGAA AGTGAGGTTC AAGTTACAGT GCAAGGTGAC
    AAGGCTGTTG TCTCCTTTGA ACCATCAGCG GCACCGACAC CGAAGAATCG TATTTTTGCC
    TTTTCTTTCT TGCCGTCCAC TGCGCCATCC TTCCCTTCAC CCACCCGGAA CCCTGAGGTG
    AGAACGCCCA AGTCAGCAAC TCAGCCACAA ACAACAGAAA CTAATCTCCA AACTGCTCCT
    AAACTTTCTA CATCTACATC CACCACTGGG ACAAGCCATC TTGTAAAATG TGCGGAGAAG
    GAGAAAACTT TCTGTGTGAA TGGAGGGGAG TGCTTCATGG TGAAAGACCT TTCAAACCCC
    TCGAGATACT TGTGCAAGTG CCCAAATGAG TTTACTGGTG ATCGCTGCCA AAACTACGTA
    ATGGCCAGCT TCTACAGTAC GTCCACTCCC TTTCTGTCTC TGCCTGAATA G

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu28430
    Clone ID Related Accession (Same CDS sequence) NM_001160002.2 , NM_001160002.1
    Accession Version NM_001160002.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 585bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-20
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform HRG-gamma2
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC083977.5, EU363508.1 and AC103675.2. On Jun 2, 2019 this sequence version replaced NM_001160002.1. Transcript Variant: This variant (HRG-gamma2), which uses the type I promoter, lacks an internal in-frame exon and multiple 3' exons, but contains an alternate 3' terminal exon and thus differs in the 3' coding region and 3' UTR, compared to variant HRG-beta1. The resulting isoform (HRG-gamma2, also known as gamma protein isoform 1) lacks an internal segment, has a distinct C-terminus, and is shorter than isoform HRG-beta1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EU363508.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148874, SAMEA2149178 [ECO:0000348] ##Evidence-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GCTACATCTA CATCCACCAC TGGGACAAGC
    CATCTTGTAA AATGTGCGGA GAAGGAGAAA ACTTTCTGTG TGAATGGAGG GGAGTGCTTC
    ATGGTGAAAG ACCTTTCAAA CCCCTCGAGA TACTTGTGCA AGTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001153474.1
    CDS417..1001
    Translation

    Target ORF information:

    RefSeq Version NM_001160002.2
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-gamma2, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001160002.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GCTACATCTA CATCCACCAC TGGGACAAGC
    CATCTTGTAA AATGTGCGGA GAAGGAGAAA ACTTTCTGTG TGAATGGAGG GGAGTGCTTC
    ATGGTGAAAG ACCTTTCAAA CCCCTCGAGA TACTTGTGCA AGTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu28430
    Clone ID Related Accession (Same CDS sequence) NM_001160002.2 , NM_001160002.1
    Accession Version NM_001160002.1 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 585bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2018-12-22
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform HRG-gamma2
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC083977.5, EU363508.1 and AC103675.2. Transcript Variant: This variant (HRG-gamma2), which uses the type I promoter, lacks an internal in-frame exon and multiple 3' exons, but contains an alternate 3' terminal exon and thus differs in the 3' coding region and 3' UTR, compared to variant HRG-beta1. The resulting isoform (HRG-gamma2, also known as gamma protein isoform 1) lacks an internal segment, has a distinct C-terminus, and is shorter than isoform HRG-beta1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EU363508.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148874, SAMEA2149178 [ECO:0000348] ##Evidence-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GCTACATCTA CATCCACCAC TGGGACAAGC
    CATCTTGTAA AATGTGCGGA GAAGGAGAAA ACTTTCTGTG TGAATGGAGG GGAGTGCTTC
    ATGGTGAAAG ACCTTTCAAA CCCCTCGAGA TACTTGTGCA AGTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001153474.1
    CDS518..1102
    Translation

    Target ORF information:

    RefSeq Version NM_001160002.1
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-gamma2, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001160002.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GCTACATCTA CATCCACCAC TGGGACAAGC
    CATCTTGTAA AATGTGCGGA GAAGGAGAAA ACTTTCTGTG TGAATGGAGG GGAGTGCTTC
    ATGGTGAAAG ACCTTTCAAA CCCCTCGAGA TACTTGTGCA AGTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu28432
    Clone ID Related Accession (Same CDS sequence) NM_013960.5 , NM_013960.4
    Accession Version NM_013960.5 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1389bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2020-01-03
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform ndf43 proprotein
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK298132.1, AK097005.1, BC006492.2, U02326.2, M94165.1, DA805080.1, AC113209.4 and CA429204.1. On Jun 2, 2019 this sequence version replaced NM_013960.4. Transcript Variant: This variant (ndf43), which uses the type I promoter, lacks two in-frame exons but contains a different in-frame exon in the central coding region, and it also contains an additional exon that results in an alternate 3' coding region, compared to variant HRG-beta1. The resulting isoform (ndf43) has an alternate internal segment and a distinct C-terminus, and is shorter than isoform HRG-beta1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U02326.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTGCCAAC CTGGATTCAC TGGAGCAAGA
    TGTACTGAGA ATGTGCCCAT GAAAGTCCAA AACCAAGAAA AGGCGGAGGA GCTGTACCAG
    AAGAGAGTGC TGACCATAAC CGGCATCTGC ATCGCCCTCC TTGTGGTCGG CATCATGTGT
    GTGGTGGCCT ACTGCAAAAC CAAGAAACAG CGGAAAAAGC TGCATGACCG TCTTCGGCAG
    AGCCTTCGGT CTGAACGAAA CAATATGATG AACATTGCCA ATGGGCCTCA CCATCCTAAC
    CCACCCCCCG AGAATGTCCA GCTGGTGAAT CAATACGTAT CTAAAAACGT CATCTCCAGT
    GAGCATATTG TTGAGAGAGA AGCAGAGACA TCCTTTTCCA CCAGTCACTA TACTTCCACA
    GCCCATCACT CCACTACTGT CACCCAGACT CCTAGCCACA GCTGGAGCAA CGGACACACT
    GAAAGCATCC TTTCCGAAAG CCACTCTGTA ATCGTGATGT CATCCGTAGA AAACAGTAGG
    CACAGCAGCC CAACTGGGGG CCCAAGAGGA CGTCTTAATG GCACAGGAGG CCCTCGTGAA
    TGTAACAGCT TCCTCAGGCA TGCCAGAGAA ACCCCTGATT CCTACCGAGA CTCTCCTCAT
    AGTGAAAGAC ATAACCTTAT AGCTGAGCTA AGGAGAAACA AGGCACACAG ATCCAAATGC
    ATGCAGATCC AGCTATCAGC AACTCATCTT AGATCTTCTT CCATTCCCCA TTTGGGCTTC
    ATTCTCTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_039254.1
    CDS417..1805
    Translation

    Target ORF information:

    RefSeq Version NM_013960.5
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant ndf43, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_013960.5

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTGCCAAC CTGGATTCAC TGGAGCAAGA
    TGTACTGAGA ATGTGCCCAT GAAAGTCCAA AACCAAGAAA AGGCGGAGGA GCTGTACCAG
    AAGAGAGTGC TGACCATAAC CGGCATCTGC ATCGCCCTCC TTGTGGTCGG CATCATGTGT
    GTGGTGGCCT ACTGCAAAAC CAAGAAACAG CGGAAAAAGC TGCATGACCG TCTTCGGCAG
    AGCCTTCGGT CTGAACGAAA CAATATGATG AACATTGCCA ATGGGCCTCA CCATCCTAAC
    CCACCCCCCG AGAATGTCCA GCTGGTGAAT CAATACGTAT CTAAAAACGT CATCTCCAGT
    GAGCATATTG TTGAGAGAGA AGCAGAGACA TCCTTTTCCA CCAGTCACTA TACTTCCACA
    GCCCATCACT CCACTACTGT CACCCAGACT CCTAGCCACA GCTGGAGCAA CGGACACACT
    GAAAGCATCC TTTCCGAAAG CCACTCTGTA ATCGTGATGT CATCCGTAGA AAACAGTAGG
    CACAGCAGCC CAACTGGGGG CCCAAGAGGA CGTCTTAATG GCACAGGAGG CCCTCGTGAA
    TGTAACAGCT TCCTCAGGCA TGCCAGAGAA ACCCCTGATT CCTACCGAGA CTCTCCTCAT
    AGTGAAAGAC ATAACCTTAT AGCTGAGCTA AGGAGAAACA AGGCACACAG ATCCAAATGC
    ATGCAGATCC AGCTATCAGC AACTCATCTT AGATCTTCTT CCATTCCCCA TTTGGGCTTC
    ATTCTCTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu28432
    Clone ID Related Accession (Same CDS sequence) NM_013960.5 , NM_013960.4
    Accession Version NM_013960.4 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1389bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-02-24
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform ndf43 proprotein
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK298132.1, AK097005.1, BC006492.2, U02326.2, M94165.1, DA805080.1, AC113209.4 and CA429204.1. On Apr 8, 2016 this sequence version replaced NM_013960.3. Transcript Variant: This variant (ndf43), which uses the type I promoter, lacks two in-frame exons but contains a different in-frame exon in the central coding region, and it also contains an additional exon that results in an alternate 3' coding region, compared to variant HRG-beta1. The resulting isoform (ndf43) has an alternate internal segment and a distinct C-terminus, and is shorter than isoform HRG-beta1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U02326.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTGCCAAC CTGGATTCAC TGGAGCAAGA
    TGTACTGAGA ATGTGCCCAT GAAAGTCCAA AACCAAGAAA AGGCGGAGGA GCTGTACCAG
    AAGAGAGTGC TGACCATAAC CGGCATCTGC ATCGCCCTCC TTGTGGTCGG CATCATGTGT
    GTGGTGGCCT ACTGCAAAAC CAAGAAACAG CGGAAAAAGC TGCATGACCG TCTTCGGCAG
    AGCCTTCGGT CTGAACGAAA CAATATGATG AACATTGCCA ATGGGCCTCA CCATCCTAAC
    CCACCCCCCG AGAATGTCCA GCTGGTGAAT CAATACGTAT CTAAAAACGT CATCTCCAGT
    GAGCATATTG TTGAGAGAGA AGCAGAGACA TCCTTTTCCA CCAGTCACTA TACTTCCACA
    GCCCATCACT CCACTACTGT CACCCAGACT CCTAGCCACA GCTGGAGCAA CGGACACACT
    GAAAGCATCC TTTCCGAAAG CCACTCTGTA ATCGTGATGT CATCCGTAGA AAACAGTAGG
    CACAGCAGCC CAACTGGGGG CCCAAGAGGA CGTCTTAATG GCACAGGAGG CCCTCGTGAA
    TGTAACAGCT TCCTCAGGCA TGCCAGAGAA ACCCCTGATT CCTACCGAGA CTCTCCTCAT
    AGTGAAAGAC ATAACCTTAT AGCTGAGCTA AGGAGAAACA AGGCACACAG ATCCAAATGC
    ATGCAGATCC AGCTATCAGC AACTCATCTT AGATCTTCTT CCATTCCCCA TTTGGGCTTC
    ATTCTCTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_039254.1
    CDS518..1906
    Translation

    Target ORF information:

    RefSeq Version NM_013960.4
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant ndf43, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_013960.4

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTGCCAAC CTGGATTCAC TGGAGCAAGA
    TGTACTGAGA ATGTGCCCAT GAAAGTCCAA AACCAAGAAA AGGCGGAGGA GCTGTACCAG
    AAGAGAGTGC TGACCATAAC CGGCATCTGC ATCGCCCTCC TTGTGGTCGG CATCATGTGT
    GTGGTGGCCT ACTGCAAAAC CAAGAAACAG CGGAAAAAGC TGCATGACCG TCTTCGGCAG
    AGCCTTCGGT CTGAACGAAA CAATATGATG AACATTGCCA ATGGGCCTCA CCATCCTAAC
    CCACCCCCCG AGAATGTCCA GCTGGTGAAT CAATACGTAT CTAAAAACGT CATCTCCAGT
    GAGCATATTG TTGAGAGAGA AGCAGAGACA TCCTTTTCCA CCAGTCACTA TACTTCCACA
    GCCCATCACT CCACTACTGT CACCCAGACT CCTAGCCACA GCTGGAGCAA CGGACACACT
    GAAAGCATCC TTTCCGAAAG CCACTCTGTA ATCGTGATGT CATCCGTAGA AAACAGTAGG
    CACAGCAGCC CAACTGGGGG CCCAAGAGGA CGTCTTAATG GCACAGGAGG CCCTCGTGAA
    TGTAACAGCT TCCTCAGGCA TGCCAGAGAA ACCCCTGATT CCTACCGAGA CTCTCCTCAT
    AGTGAAAGAC ATAACCTTAT AGCTGAGCTA AGGAGAAACA AGGCACACAG ATCCAAATGC
    ATGCAGATCC AGCTATCAGC AACTCATCTT AGATCTTCTT CCATTCCCCA TTTGGGCTTC
    ATTCTCTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu28433
    Clone ID Related Accession (Same CDS sequence) NM_001160007.2 , NM_001160007.1
    Accession Version NM_001160007.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 534bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-20
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform HRG-gamma3
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC083977.5, EU363509.1 and AC103675.2. On Jun 2, 2019 this sequence version replaced NM_001160007.1. Transcript Variant: This variant (HRG-gamma3), which uses the type I promoter, lacks two internal in-frame exons and multiple 3' exons, but contains an alternate 3' terminal exon that results in an early stop codon and an alternate 3' UTR, compared to variant HRG-beta1. The resulting isoform (HRG-gamma3, also known as gamma protein isoform 2) lacks an internal segment and is shorter at the C-terminus, compared to isoform HRG-beta1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EU363509.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145122, SAMEA2148874 [ECO:0000348] ##Evidence-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG CTACATCTAC ATCCACCACT
    GGGACAAGCC ATCTTGTAAA ATGTGCGGAG AAGGAGAAAA CTTTCTGTGT GAATGGAGGG
    GAGTGCTTCA TGGTGAAAGA CCTTTCAAAC CCCTCGAGAT ACTTGTGCAA GTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001153479.1
    CDS417..950
    Translation

    Target ORF information:

    RefSeq Version NM_001160007.2
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-gamma3, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001160007.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG CTACATCTAC ATCCACCACT
    GGGACAAGCC ATCTTGTAAA ATGTGCGGAG AAGGAGAAAA CTTTCTGTGT GAATGGAGGG
    GAGTGCTTCA TGGTGAAAGA CCTTTCAAAC CCCTCGAGAT ACTTGTGCAA GTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu28433
    Clone ID Related Accession (Same CDS sequence) NM_001160007.2 , NM_001160007.1
    Accession Version NM_001160007.1 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 534bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2018-12-22
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform HRG-gamma3
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC083977.5, EU363509.1 and AC103675.2. Transcript Variant: This variant (HRG-gamma3), which uses the type I promoter, lacks two internal in-frame exons and multiple 3' exons, but contains an alternate 3' terminal exon that results in an early stop codon and an alternate 3' UTR, compared to variant HRG-beta1. The resulting isoform (HRG-gamma3, also known as gamma protein isoform 2) lacks an internal segment and is shorter at the C-terminus, compared to isoform HRG-beta1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EU363509.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145122, SAMEA2148874 [ECO:0000348] ##Evidence-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG CTACATCTAC ATCCACCACT
    GGGACAAGCC ATCTTGTAAA ATGTGCGGAG AAGGAGAAAA CTTTCTGTGT GAATGGAGGG
    GAGTGCTTCA TGGTGAAAGA CCTTTCAAAC CCCTCGAGAT ACTTGTGCAA GTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001153479.1
    CDS518..1051
    Translation

    Target ORF information:

    RefSeq Version NM_001160007.1
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-gamma3, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001160007.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG CTACATCTAC ATCCACCACT
    GGGACAAGCC ATCTTGTAAA ATGTGCGGAG AAGGAGAAAA CTTTCTGTGT GAATGGAGGG
    GAGTGCTTCA TGGTGAAAGA CCTTTCAAAC CCCTCGAGAT ACTTGTGCAA GTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu28442
    Clone ID Related Accession (Same CDS sequence) NM_001160004.2 , NM_001160004.3
    Accession Version NM_001160004.2 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1380bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2018-12-22
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform ndf43b
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC083977.5, EU363510.1, BC144446.1, DA805080.1, AC113209.4 and CA429204.1. On Apr 8, 2016 this sequence version replaced NM_001160004.1. Transcript Variant: This variant (ndf43b), which uses the type I promoter, lacks an alternate in-frame exon in the central coding region, and contains an additional exon that results in an alternate 3' coding region, compared to variant HRG-beta1. The resulting isoform (ndf43b, also known as ndf43-beta2) lacks an internal segment, has a distinct C-terminus, and is shorter than isoform HRG-beta1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC144446.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTGCCCAA ATGAGTTTAC TGGTGATCGC
    TGCCAAAACT ACGTAATGGC CAGCTTCTAC AAGGCGGAGG AGCTGTACCA GAAGAGAGTG
    CTGACCATAA CCGGCATCTG CATCGCCCTC CTTGTGGTCG GCATCATGTG TGTGGTGGCC
    TACTGCAAAA CCAAGAAACA GCGGAAAAAG CTGCATGACC GTCTTCGGCA GAGCCTTCGG
    TCTGAACGAA ACAATATGAT GAACATTGCC AATGGGCCTC ACCATCCTAA CCCACCCCCC
    GAGAATGTCC AGCTGGTGAA TCAATACGTA TCTAAAAACG TCATCTCCAG TGAGCATATT
    GTTGAGAGAG AAGCAGAGAC ATCCTTTTCC ACCAGTCACT ATACTTCCAC AGCCCATCAC
    TCCACTACTG TCACCCAGAC TCCTAGCCAC AGCTGGAGCA ACGGACACAC TGAAAGCATC
    CTTTCCGAAA GCCACTCTGT AATCGTGATG TCATCCGTAG AAAACAGTAG GCACAGCAGC
    CCAACTGGGG GCCCAAGAGG ACGTCTTAAT GGCACAGGAG GCCCTCGTGA ATGTAACAGC
    TTCCTCAGGC ATGCCAGAGA AACCCCTGAT TCCTACCGAG ACTCTCCTCA TAGTGAAAGA
    CATAACCTTA TAGCTGAGCT AAGGAGAAAC AAGGCACACA GATCCAAATG CATGCAGATC
    CAGCTATCAG CAACTCATCT TAGATCTTCT TCCATTCCCC ATTTGGGCTT CATTCTCTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001153476.1
    CDS518..1897
    Translation

    Target ORF information:

    RefSeq Version NM_001160004.2
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant ndf43b, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001160004.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTGCCCAA ATGAGTTTAC TGGTGATCGC
    TGCCAAAACT ACGTAATGGC CAGCTTCTAC AAGGCGGAGG AGCTGTACCA GAAGAGAGTG
    CTGACCATAA CCGGCATCTG CATCGCCCTC CTTGTGGTCG GCATCATGTG TGTGGTGGCC
    TACTGCAAAA CCAAGAAACA GCGGAAAAAG CTGCATGACC GTCTTCGGCA GAGCCTTCGG
    TCTGAACGAA ACAATATGAT GAACATTGCC AATGGGCCTC ACCATCCTAA CCCACCCCCC
    GAGAATGTCC AGCTGGTGAA TCAATACGTA TCTAAAAACG TCATCTCCAG TGAGCATATT
    GTTGAGAGAG AAGCAGAGAC ATCCTTTTCC ACCAGTCACT ATACTTCCAC AGCCCATCAC
    TCCACTACTG TCACCCAGAC TCCTAGCCAC AGCTGGAGCA ACGGACACAC TGAAAGCATC
    CTTTCCGAAA GCCACTCTGT AATCGTGATG TCATCCGTAG AAAACAGTAG GCACAGCAGC
    CCAACTGGGG GCCCAAGAGG ACGTCTTAAT GGCACAGGAG GCCCTCGTGA ATGTAACAGC
    TTCCTCAGGC ATGCCAGAGA AACCCCTGAT TCCTACCGAG ACTCTCCTCA TAGTGAAAGA
    CATAACCTTA TAGCTGAGCT AAGGAGAAAC AAGGCACACA GATCCAAATG CATGCAGATC
    CAGCTATCAG CAACTCATCT TAGATCTTCT TCCATTCCCC ATTTGGGCTT CATTCTCTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu28442
    Clone ID Related Accession (Same CDS sequence) NM_001160004.2 , NM_001160004.3
    Accession Version NM_001160004.3 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1380bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-20
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform ndf43b
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC083977.5, EU363510.1, BC144446.1, DA805080.1, AC113209.4 and CA429204.1. On Jun 2, 2019 this sequence version replaced NM_001160004.2. Transcript Variant: This variant (ndf43b), which uses the type I promoter, lacks an alternate in-frame exon in the central coding region, and contains an additional exon that results in an alternate 3' coding region, compared to variant HRG-beta1. The resulting isoform (ndf43b, also known as ndf43-beta2) lacks an internal segment, has a distinct C-terminus, and is shorter than isoform HRG-beta1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC144446.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTGCCCAA ATGAGTTTAC TGGTGATCGC
    TGCCAAAACT ACGTAATGGC CAGCTTCTAC AAGGCGGAGG AGCTGTACCA GAAGAGAGTG
    CTGACCATAA CCGGCATCTG CATCGCCCTC CTTGTGGTCG GCATCATGTG TGTGGTGGCC
    TACTGCAAAA CCAAGAAACA GCGGAAAAAG CTGCATGACC GTCTTCGGCA GAGCCTTCGG
    TCTGAACGAA ACAATATGAT GAACATTGCC AATGGGCCTC ACCATCCTAA CCCACCCCCC
    GAGAATGTCC AGCTGGTGAA TCAATACGTA TCTAAAAACG TCATCTCCAG TGAGCATATT
    GTTGAGAGAG AAGCAGAGAC ATCCTTTTCC ACCAGTCACT ATACTTCCAC AGCCCATCAC
    TCCACTACTG TCACCCAGAC TCCTAGCCAC AGCTGGAGCA ACGGACACAC TGAAAGCATC
    CTTTCCGAAA GCCACTCTGT AATCGTGATG TCATCCGTAG AAAACAGTAG GCACAGCAGC
    CCAACTGGGG GCCCAAGAGG ACGTCTTAAT GGCACAGGAG GCCCTCGTGA ATGTAACAGC
    TTCCTCAGGC ATGCCAGAGA AACCCCTGAT TCCTACCGAG ACTCTCCTCA TAGTGAAAGA
    CATAACCTTA TAGCTGAGCT AAGGAGAAAC AAGGCACACA GATCCAAATG CATGCAGATC
    CAGCTATCAG CAACTCATCT TAGATCTTCT TCCATTCCCC ATTTGGGCTT CATTCTCTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001153476.1
    CDS417..1796
    Translation

    Target ORF information:

    RefSeq Version NM_001160004.3
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant ndf43b, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001160004.3

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTGCCCAA ATGAGTTTAC TGGTGATCGC
    TGCCAAAACT ACGTAATGGC CAGCTTCTAC AAGGCGGAGG AGCTGTACCA GAAGAGAGTG
    CTGACCATAA CCGGCATCTG CATCGCCCTC CTTGTGGTCG GCATCATGTG TGTGGTGGCC
    TACTGCAAAA CCAAGAAACA GCGGAAAAAG CTGCATGACC GTCTTCGGCA GAGCCTTCGG
    TCTGAACGAA ACAATATGAT GAACATTGCC AATGGGCCTC ACCATCCTAA CCCACCCCCC
    GAGAATGTCC AGCTGGTGAA TCAATACGTA TCTAAAAACG TCATCTCCAG TGAGCATATT
    GTTGAGAGAG AAGCAGAGAC ATCCTTTTCC ACCAGTCACT ATACTTCCAC AGCCCATCAC
    TCCACTACTG TCACCCAGAC TCCTAGCCAC AGCTGGAGCA ACGGACACAC TGAAAGCATC
    CTTTCCGAAA GCCACTCTGT AATCGTGATG TCATCCGTAG AAAACAGTAG GCACAGCAGC
    CCAACTGGGG GCCCAAGAGG ACGTCTTAAT GGCACAGGAG GCCCTCGTGA ATGTAACAGC
    TTCCTCAGGC ATGCCAGAGA AACCCCTGAT TCCTACCGAG ACTCTCCTCA TAGTGAAAGA
    CATAACCTTA TAGCTGAGCT AAGGAGAAAC AAGGCACACA GATCCAAATG CATGCAGATC
    CAGCTATCAG CAACTCATCT TAGATCTTCT TCCATTCCCC ATTTGGGCTT CATTCTCTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu28447
    Clone ID Related Accession (Same CDS sequence) NM_013958.3
    Accession Version NM_013958.3 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 726bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-20
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform HRG-beta3
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK298132.1, AK097005.1, M94168.1 and M94165.1. On or before May 13, 2009 this sequence version replaced NM_013961.2, NM_013958.2. Transcript Variant: This variant (HRG-beta3), which uses the type I promoter, lacks multiple 3' exons but contains an alternate 3' terminal exon that results in an early stop codon, compared to variant HRG-beta1. The resulting isoform (HRG-beta3, also known as GGF or GGFHFB1) is shorter at the C-terminus, compared to isoform HRG-beta1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M94168.1, BC006492.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTGCCCAA ATGAGTTTAC TGGTGATCGC
    TGCCAAAACT ACGTAATGGC CAGCTTCTAC AGTACGTCCA CTCCCTTTCT GTCTCTGCCT
    GAATAG

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_039252.2
    CDS518..1243
    Translation

    Target ORF information:

    RefSeq Version NM_013958.3
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta3, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_013958.3

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG AGATCATCAC TGGTATGCCA
    GCCTCAACTG AAGGAGCATA TGTGTCTTCA GAGTCTCCCA TTAGAATATC AGTATCCACA
    GAAGGAGCAA ATACTTCTTC ATCTACATCT ACATCCACCA CTGGGACAAG CCATCTTGTA
    AAATGTGCGG AGAAGGAGAA AACTTTCTGT GTGAATGGAG GGGAGTGCTT CATGGTGAAA
    GACCTTTCAA ACCCCTCGAG ATACTTGTGC AAGTGCCCAA ATGAGTTTAC TGGTGATCGC
    TGCCAAAACT ACGTAATGGC CAGCTTCTAC AGTACGTCCA CTCCCTTTCT GTCTCTGCCT
    GAATAG

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu28451
    Clone ID Related Accession (Same CDS sequence) NM_001159996.2
    Accession Version NM_001159996.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 927bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-19
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform ndf43c
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CN603661.1, DC425692.1, AK293240.1, BC144446.1, DA805080.1, AC113209.4 and CA429204.1. On Apr 8, 2016 this sequence version replaced NM_001159996.1. Transcript Variant: This variant (ndf43c), which uses the type VI promoter, lacks multiple 5' exons but contains an alternate 5' terminal exon, and it also lacks two in-frame exons in the central coding region and includes an additional exon that results in an alternate 3' coding region, compared to variant HRG-beta1. The resulting isoform (ndf43c, also known as ndf43) has distinct N- and C-termini, lacks an internal segment, and is shorter than isoform HRG-beta1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK293240.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145240, SAMN03465419 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGCAGATTC CTAAACACAT AAGCATTGAA GATATTACAG CTACATCTAC ATCCACCACT 
    GGGACAAGCC ATCTTGTAAA ATGTGCGGAG AAGGAGAAAA CTTTCTGTGT GAATGGAGGG
    GAGTGCTTCA TGGTGAAAGA CCTTTCAAAC CCCTCGAGAT ACTTGTGCAA GTGCCAACCT
    GGATTCACTG GAGCAAGATG TACTGAGAAT GTGCCCATGA AAGTCCAAAA CCAAGAAAAG
    GCGGAGGAGC TGTACCAGAA GAGAGTGCTG ACCATAACCG GCATCTGCAT CGCCCTCCTT
    GTGGTCGGCA TCATGTGTGT GGTGGCCTAC TGCAAAACCA AGAAACAGCG GAAAAAGCTG
    CATGACCGTC TTCGGCAGAG CCTTCGGTCT GAACGAAACA ATATGATGAA CATTGCCAAT
    GGGCCTCACC ATCCTAACCC ACCCCCCGAG AATGTCCAGC TGGTGAATCA ATACGTATCT
    AAAAACGTCA TCTCCAGTGA GCATATTGTT GAGAGAGAAG CAGAGACATC CTTTTCCACC
    AGTCACTATA CTTCCACAGC CCATCACTCC ACTACTGTCA CCCAGACTCC TAGCCACAGC
    TGGAGCAACG GACACACTGA AAGCATCCTT TCCGAAAGCC ACTCTGTAAT CGTGATGTCA
    TCCGTAGAAA ACAGTAGGCA CAGCAGCCCA ACTGGGGGCC CAAGAGGACG TCTTAATGGC
    ACAGGAGGCC CTCGTGAATG TAACAGCTTC CTCAGGCATG CCAGAGAAAC CCCTGATTCC
    TACCGAGACT CTCCTCATAG TGAAAGACAT AACCTTATAG CTGAGCTAAG GAGAAACAAG
    GCACACAGAT CCAAATGCAT GCAGATCCAG CTATCAGCAA CTCATCTTAG ATCTTCTTCC
    ATTCCCCATT TGGGCTTCAT TCTCTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001153468.1
    CDS251..1177
    Translation

    Target ORF information:

    RefSeq Version NM_001159996.2
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant ndf43c, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001159996.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGCAGATTC CTAAACACAT AAGCATTGAA GATATTACAG CTACATCTAC ATCCACCACT 
    GGGACAAGCC ATCTTGTAAA ATGTGCGGAG AAGGAGAAAA CTTTCTGTGT GAATGGAGGG
    GAGTGCTTCA TGGTGAAAGA CCTTTCAAAC CCCTCGAGAT ACTTGTGCAA GTGCCAACCT
    GGATTCACTG GAGCAAGATG TACTGAGAAT GTGCCCATGA AAGTCCAAAA CCAAGAAAAG
    GCGGAGGAGC TGTACCAGAA GAGAGTGCTG ACCATAACCG GCATCTGCAT CGCCCTCCTT
    GTGGTCGGCA TCATGTGTGT GGTGGCCTAC TGCAAAACCA AGAAACAGCG GAAAAAGCTG
    CATGACCGTC TTCGGCAGAG CCTTCGGTCT GAACGAAACA ATATGATGAA CATTGCCAAT
    GGGCCTCACC ATCCTAACCC ACCCCCCGAG AATGTCCAGC TGGTGAATCA ATACGTATCT
    AAAAACGTCA TCTCCAGTGA GCATATTGTT GAGAGAGAAG CAGAGACATC CTTTTCCACC
    AGTCACTATA CTTCCACAGC CCATCACTCC ACTACTGTCA CCCAGACTCC TAGCCACAGC
    TGGAGCAACG GACACACTGA AAGCATCCTT TCCGAAAGCC ACTCTGTAAT CGTGATGTCA
    TCCGTAGAAA ACAGTAGGCA CAGCAGCCCA ACTGGGGGCC CAAGAGGACG TCTTAATGGC
    ACAGGAGGCC CTCGTGAATG TAACAGCTTC CTCAGGCATG CCAGAGAAAC CCCTGATTCC
    TACCGAGACT CTCCTCATAG TGAAAGACAT AACCTTATAG CTGAGCTAAG GAGAAACAAG
    GCACACAGAT CCAAATGCAT GCAGATCCAG CTATCAGCAA CTCATCTTAG ATCTTCTTCC
    ATTCCCCATT TGGGCTTCAT TCTCTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu58208
    Clone ID Related Accession (Same CDS sequence) NM_001322206.1 , NM_001322206.2
    Accession Version NM_001322206.1 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1569bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2018-12-22
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform III-2
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK289927.1, M94166.1, BC144446.1, AC113209.4 and CA429204.1. On Apr 8, 2016 this sequence version replaced XM_011544513.1. Transcript Variant: This variant (III-2), which uses the type III promoter, lacks several 5' exons but contains an alternate 5' terminal exon and thus differs in the 5' UTR and 5' coding region, and it also includes an additional exon that results in an alternate 3' coding region, compared to variant HRG-beta1. The resulting isoform (III-2) has distinct N- and C-termini and is shorter than isoform HRG-beta1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.51594.1, SRR1803615.28644.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    ATGGAGATTT ATTCCCCAGA CATGTCTGAG GTCGCCGCCG AGAGGTCCTC CAGCCCCTCC 
    ACTCAGCTGA GTGCAGACCC ATCTCTTGAT GGGCTTCCGG CAGCAGAAGA CATGCCAGAG
    CCCCAGACTG AAGATGGGAG AACCCCTGGA CTCGTGGGCC TGGCCGTGCC CTGCTGTGCG
    TGCCTAGAAG CTGAGCGCCT GAGAGGTTGC CTCAACTCAG AGAAAATCTG CATTGTCCCC
    ATCCTGGCTT GCCTGGTCAG CCTCTGCCTC TGCATCGCCG GCCTCAAGTG GGTATTTGTG
    GACAAGATCT TTGAATATGA CTCTCCTACT CACCTTGACC CTGGGGGGTT AGGCCAGGAC
    CCTATTATTT CTCTGGACGC AACTGCTGCC TCAGCTGTGT GGGTGTCGTC TGAGGCATAC
    ACTTCACCTG TCTCTAGGGC TCAATCTGAA AGTGAGGTTC AAGTTACAGT GCAAGGTGAC
    AAGGCTGTTG TCTCCTTTGA ACCATCAGCG GCACCGACAC CGAAGAATCG TATTTTTGCC
    TTTTCTTTCT TGCCGTCCAC TGCGCCATCC TTCCCTTCAC CCACCCGGAA CCCTGAGGTG
    AGAACGCCCA AGTCAGCAAC TCAGCCACAA ACAACAGAAA CTAATCTCCA AACTGCTCCT
    AAACTTTCTA CATCTACATC CACCACTGGG ACAAGCCATC TTGTAAAATG TGCGGAGAAG
    GAGAAAACTT TCTGTGTGAA TGGAGGGGAG TGCTTCATGG TGAAAGACCT TTCAAACCCC
    TCGAGATACT TGTGCAAGTG CCCAAATGAG TTTACTGGTG ATCGCTGCCA AAACTACGTA
    ATGGCCAGCT TCTACAAGCA TCTTGGGATT GAATTTATGG AGGCGGAGGA GCTGTACCAG
    AAGAGAGTGC TGACCATAAC CGGCATCTGC ATCGCCCTCC TTGTGGTCGG CATCATGTGT
    GTGGTGGCCT ACTGCAAAAC CAAGAAACAG CGGAAAAAGC TGCATGACCG TCTTCGGCAG
    AGCCTTCGGT CTGAACGAAA CAATATGATG AACATTGCCA ATGGGCCTCA CCATCCTAAC
    CCACCCCCCG AGAATGTCCA GCTGGTGAAT CAATACGTAT CTAAAAACGT CATCTCCAGT
    GAGCATATTG TTGAGAGAGA AGCAGAGACA TCCTTTTCCA CCAGTCACTA TACTTCCACA
    GCCCATCACT CCACTACTGT CACCCAGACT CCTAGCCACA GCTGGAGCAA CGGACACACT
    GAAAGCATCC TTTCCGAAAG CCACTCTGTA ATCGTGATGT CATCCGTAGA AAACAGTAGG
    CACAGCAGCC CAACTGGGGG CCCAAGAGGA CGTCTTAATG GCACAGGAGG CCCTCGTGAA
    TGTAACAGCT TCCTCAGGCA TGCCAGAGAA ACCCCTGATT CCTACCGAGA CTCTCCTCAT
    AGTGAAAGAC ATAACCTTAT AGCTGAGCTA AGGAGAAACA AGGCACACAG ATCCAAATGC
    ATGCAGATCC AGCTATCAGC AACTCATCTT AGATCTTCTT CCATTCCCCA TTTGGGCTTC
    ATTCTCTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001309135.1
    CDS987..2555
    Translation

    Target ORF information:

    RefSeq Version NM_001322206.1
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant III-2, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001322206.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    ATGGAGATTT ATTCCCCAGA CATGTCTGAG GTCGCCGCCG AGAGGTCCTC CAGCCCCTCC 
    ACTCAGCTGA GTGCAGACCC ATCTCTTGAT GGGCTTCCGG CAGCAGAAGA CATGCCAGAG
    CCCCAGACTG AAGATGGGAG AACCCCTGGA CTCGTGGGCC TGGCCGTGCC CTGCTGTGCG
    TGCCTAGAAG CTGAGCGCCT GAGAGGTTGC CTCAACTCAG AGAAAATCTG CATTGTCCCC
    ATCCTGGCTT GCCTGGTCAG CCTCTGCCTC TGCATCGCCG GCCTCAAGTG GGTATTTGTG
    GACAAGATCT TTGAATATGA CTCTCCTACT CACCTTGACC CTGGGGGGTT AGGCCAGGAC
    CCTATTATTT CTCTGGACGC AACTGCTGCC TCAGCTGTGT GGGTGTCGTC TGAGGCATAC
    ACTTCACCTG TCTCTAGGGC TCAATCTGAA AGTGAGGTTC AAGTTACAGT GCAAGGTGAC
    AAGGCTGTTG TCTCCTTTGA ACCATCAGCG GCACCGACAC CGAAGAATCG TATTTTTGCC
    TTTTCTTTCT TGCCGTCCAC TGCGCCATCC TTCCCTTCAC CCACCCGGAA CCCTGAGGTG
    AGAACGCCCA AGTCAGCAAC TCAGCCACAA ACAACAGAAA CTAATCTCCA AACTGCTCCT
    AAACTTTCTA CATCTACATC CACCACTGGG ACAAGCCATC TTGTAAAATG TGCGGAGAAG
    GAGAAAACTT TCTGTGTGAA TGGAGGGGAG TGCTTCATGG TGAAAGACCT TTCAAACCCC
    TCGAGATACT TGTGCAAGTG CCCAAATGAG TTTACTGGTG ATCGCTGCCA AAACTACGTA
    ATGGCCAGCT TCTACAAGCA TCTTGGGATT GAATTTATGG AGGCGGAGGA GCTGTACCAG
    AAGAGAGTGC TGACCATAAC CGGCATCTGC ATCGCCCTCC TTGTGGTCGG CATCATGTGT
    GTGGTGGCCT ACTGCAAAAC CAAGAAACAG CGGAAAAAGC TGCATGACCG TCTTCGGCAG
    AGCCTTCGGT CTGAACGAAA CAATATGATG AACATTGCCA ATGGGCCTCA CCATCCTAAC
    CCACCCCCCG AGAATGTCCA GCTGGTGAAT CAATACGTAT CTAAAAACGT CATCTCCAGT
    GAGCATATTG TTGAGAGAGA AGCAGAGACA TCCTTTTCCA CCAGTCACTA TACTTCCACA
    GCCCATCACT CCACTACTGT CACCCAGACT CCTAGCCACA GCTGGAGCAA CGGACACACT
    GAAAGCATCC TTTCCGAAAG CCACTCTGTA ATCGTGATGT CATCCGTAGA AAACAGTAGG
    CACAGCAGCC CAACTGGGGG CCCAAGAGGA CGTCTTAATG GCACAGGAGG CCCTCGTGAA
    TGTAACAGCT TCCTCAGGCA TGCCAGAGAA ACCCCTGATT CCTACCGAGA CTCTCCTCAT
    AGTGAAAGAC ATAACCTTAT AGCTGAGCTA AGGAGAAACA AGGCACACAG ATCCAAATGC
    ATGCAGATCC AGCTATCAGC AACTCATCTT AGATCTTCTT CCATTCCCCA TTTGGGCTTC
    ATTCTCTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu58208
    Clone ID Related Accession (Same CDS sequence) NM_001322206.1 , NM_001322206.2
    Accession Version NM_001322206.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1569bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-20
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform III-2
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK289927.1, M94166.1, BC144446.1, AC113209.4 and CA429204.1. On Jun 2, 2019 this sequence version replaced NM_001322206.1. Transcript Variant: This variant (III-2), which uses the type III promoter, lacks several 5' exons but contains an alternate 5' terminal exon and thus differs in the 5' UTR and 5' coding region, and it also includes an additional exon that results in an alternate 3' coding region, compared to variant HRG-beta1. The resulting isoform (III-2) has distinct N- and C-termini and is shorter than isoform HRG-beta1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.51594.1, SRR1803615.28644.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    ATGGAGATTT ATTCCCCAGA CATGTCTGAG GTCGCCGCCG AGAGGTCCTC CAGCCCCTCC 
    ACTCAGCTGA GTGCAGACCC ATCTCTTGAT GGGCTTCCGG CAGCAGAAGA CATGCCAGAG
    CCCCAGACTG AAGATGGGAG AACCCCTGGA CTCGTGGGCC TGGCCGTGCC CTGCTGTGCG
    TGCCTAGAAG CTGAGCGCCT GAGAGGTTGC CTCAACTCAG AGAAAATCTG CATTGTCCCC
    ATCCTGGCTT GCCTGGTCAG CCTCTGCCTC TGCATCGCCG GCCTCAAGTG GGTATTTGTG
    GACAAGATCT TTGAATATGA CTCTCCTACT CACCTTGACC CTGGGGGGTT AGGCCAGGAC
    CCTATTATTT CTCTGGACGC AACTGCTGCC TCAGCTGTGT GGGTGTCGTC TGAGGCATAC
    ACTTCACCTG TCTCTAGGGC TCAATCTGAA AGTGAGGTTC AAGTTACAGT GCAAGGTGAC
    AAGGCTGTTG TCTCCTTTGA ACCATCAGCG GCACCGACAC CGAAGAATCG TATTTTTGCC
    TTTTCTTTCT TGCCGTCCAC TGCGCCATCC TTCCCTTCAC CCACCCGGAA CCCTGAGGTG
    AGAACGCCCA AGTCAGCAAC TCAGCCACAA ACAACAGAAA CTAATCTCCA AACTGCTCCT
    AAACTTTCTA CATCTACATC CACCACTGGG ACAAGCCATC TTGTAAAATG TGCGGAGAAG
    GAGAAAACTT TCTGTGTGAA TGGAGGGGAG TGCTTCATGG TGAAAGACCT TTCAAACCCC
    TCGAGATACT TGTGCAAGTG CCCAAATGAG TTTACTGGTG ATCGCTGCCA AAACTACGTA
    ATGGCCAGCT TCTACAAGCA TCTTGGGATT GAATTTATGG AGGCGGAGGA GCTGTACCAG
    AAGAGAGTGC TGACCATAAC CGGCATCTGC ATCGCCCTCC TTGTGGTCGG CATCATGTGT
    GTGGTGGCCT ACTGCAAAAC CAAGAAACAG CGGAAAAAGC TGCATGACCG TCTTCGGCAG
    AGCCTTCGGT CTGAACGAAA CAATATGATG AACATTGCCA ATGGGCCTCA CCATCCTAAC
    CCACCCCCCG AGAATGTCCA GCTGGTGAAT CAATACGTAT CTAAAAACGT CATCTCCAGT
    GAGCATATTG TTGAGAGAGA AGCAGAGACA TCCTTTTCCA CCAGTCACTA TACTTCCACA
    GCCCATCACT CCACTACTGT CACCCAGACT CCTAGCCACA GCTGGAGCAA CGGACACACT
    GAAAGCATCC TTTCCGAAAG CCACTCTGTA ATCGTGATGT CATCCGTAGA AAACAGTAGG
    CACAGCAGCC CAACTGGGGG CCCAAGAGGA CGTCTTAATG GCACAGGAGG CCCTCGTGAA
    TGTAACAGCT TCCTCAGGCA TGCCAGAGAA ACCCCTGATT CCTACCGAGA CTCTCCTCAT
    AGTGAAAGAC ATAACCTTAT AGCTGAGCTA AGGAGAAACA AGGCACACAG ATCCAAATGC
    ATGCAGATCC AGCTATCAGC AACTCATCTT AGATCTTCTT CCATTCCCCA TTTGGGCTTC
    ATTCTCTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001309135.1
    CDS630..2198
    Translation

    Target ORF information:

    RefSeq Version NM_001322206.2
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant III-2, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001322206.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    ATGGAGATTT ATTCCCCAGA CATGTCTGAG GTCGCCGCCG AGAGGTCCTC CAGCCCCTCC 
    ACTCAGCTGA GTGCAGACCC ATCTCTTGAT GGGCTTCCGG CAGCAGAAGA CATGCCAGAG
    CCCCAGACTG AAGATGGGAG AACCCCTGGA CTCGTGGGCC TGGCCGTGCC CTGCTGTGCG
    TGCCTAGAAG CTGAGCGCCT GAGAGGTTGC CTCAACTCAG AGAAAATCTG CATTGTCCCC
    ATCCTGGCTT GCCTGGTCAG CCTCTGCCTC TGCATCGCCG GCCTCAAGTG GGTATTTGTG
    GACAAGATCT TTGAATATGA CTCTCCTACT CACCTTGACC CTGGGGGGTT AGGCCAGGAC
    CCTATTATTT CTCTGGACGC AACTGCTGCC TCAGCTGTGT GGGTGTCGTC TGAGGCATAC
    ACTTCACCTG TCTCTAGGGC TCAATCTGAA AGTGAGGTTC AAGTTACAGT GCAAGGTGAC
    AAGGCTGTTG TCTCCTTTGA ACCATCAGCG GCACCGACAC CGAAGAATCG TATTTTTGCC
    TTTTCTTTCT TGCCGTCCAC TGCGCCATCC TTCCCTTCAC CCACCCGGAA CCCTGAGGTG
    AGAACGCCCA AGTCAGCAAC TCAGCCACAA ACAACAGAAA CTAATCTCCA AACTGCTCCT
    AAACTTTCTA CATCTACATC CACCACTGGG ACAAGCCATC TTGTAAAATG TGCGGAGAAG
    GAGAAAACTT TCTGTGTGAA TGGAGGGGAG TGCTTCATGG TGAAAGACCT TTCAAACCCC
    TCGAGATACT TGTGCAAGTG CCCAAATGAG TTTACTGGTG ATCGCTGCCA AAACTACGTA
    ATGGCCAGCT TCTACAAGCA TCTTGGGATT GAATTTATGG AGGCGGAGGA GCTGTACCAG
    AAGAGAGTGC TGACCATAAC CGGCATCTGC ATCGCCCTCC TTGTGGTCGG CATCATGTGT
    GTGGTGGCCT ACTGCAAAAC CAAGAAACAG CGGAAAAAGC TGCATGACCG TCTTCGGCAG
    AGCCTTCGGT CTGAACGAAA CAATATGATG AACATTGCCA ATGGGCCTCA CCATCCTAAC
    CCACCCCCCG AGAATGTCCA GCTGGTGAAT CAATACGTAT CTAAAAACGT CATCTCCAGT
    GAGCATATTG TTGAGAGAGA AGCAGAGACA TCCTTTTCCA CCAGTCACTA TACTTCCACA
    GCCCATCACT CCACTACTGT CACCCAGACT CCTAGCCACA GCTGGAGCAA CGGACACACT
    GAAAGCATCC TTTCCGAAAG CCACTCTGTA ATCGTGATGT CATCCGTAGA AAACAGTAGG
    CACAGCAGCC CAACTGGGGG CCCAAGAGGA CGTCTTAATG GCACAGGAGG CCCTCGTGAA
    TGTAACAGCT TCCTCAGGCA TGCCAGAGAA ACCCCTGATT CCTACCGAGA CTCTCCTCAT
    AGTGAAAGAC ATAACCTTAT AGCTGAGCTA AGGAGAAACA AGGCACACAG ATCCAAATGC
    ATGCAGATCC AGCTATCAGC AACTCATCTT AGATCTTCTT CCATTCCCCA TTTGGGCTTC
    ATTCTCTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu58207
    Clone ID Related Accession (Same CDS sequence) XM_011544512.2
    Accession Version XM_011544512.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1959bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-05
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform X8
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011544512.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    ATGGAGCCCG ACGCCAACAG CACCAGCCGC GCGCCGGCCG CCTTCCGAGC CTCTTTCCCC 
    CCTCTGGAGA CGGGCCGGAA CCTCAAGAAG GAGGTCAGCC GGGTGCTGTG CAAGCGGTGC
    GCCTTGCCTC CCCGATTGAA AGAGATGAAA AGCCAGGAAT CGGCTGCAGG TTCCAAACTA
    GTCCTTCGGT GTGAAACCAG TTCTGAATAC TCCTCTCTCA GATTCAAGTG GTTCAAGAAT
    GGGAATGAAT TGAATCGAAA AAACAAACCA CAAAATATCA AGATACAAAA AAAGCCAGGG
    AAGTCAGAAC TTCGCATTAA CAAAGCATCA CTGGCTGATT CTGGAGAGTA TATGTGCAAA
    GTGATCAGCA AATTAGGAAA TGACAGTGCC TCTGCCAATA TCACCATCGT GGAATCAAAC
    GAGATCATCA CTGGTATGCC AGCCTCAACT GAAGGAGCAT ATGTGTCTTC AGAGTCTCCC
    ATTAGAATAT CAGTATCCAC AGAAGGAGCA AATACTTCTT CATCTACATC TACATCCACC
    ACTGGGACAA GCCATCTTGT AAAATGTGCG GAGAAGGAGA AAACTTTCTG TGTGAATGGA
    GGGGAGTGCT TCATGGTGAA AGACCTTTCA AACCCCTCGA GATACTTGTG CAAGTGCCCA
    AATGAGTTTA CTGGTGATCG CTGCCAAAAC TACGTAATGG CCAGCTTCTA CAAGCATCTT
    GGGATTGAAT TTATGGAGGC GGAGGAGCTG TACCAGAAGA GAGTGCTGAC CATAACCGGC
    ATCTGCATCG CCCTCCTTGT GGTCGGCATC ATGTGTGTGG TGGCCTACTG CAAAACCAAG
    AAACAGCGGA AAAAGCTGCA TGACCGTCTT CGGCAGAGCC TTCGGTCTGA ACGAAACAAT
    ATGATGAACA TTGCCAATGG GCCTCACCAT CCTAACCCAC CCCCCGAGAA TGTCCAGCTG
    GTGAATCAAT ACGTATCTAA AAACGTCATC TCCAGTGAGC ATATTGTTGA GAGAGAAGCA
    GAGACATCCT TTTCCACCAG TCACTATACT TCCACAGCCC ATCACTCCAC TACTGTCACC
    CAGACTCCTA GCCACAGCTG GAGCAACGGA CACACTGAAA GCATCCTTTC CGAAAGCCAC
    TCTGTAATCG TGATGTCATC CGTAGAAAAC AGTAGGCACA GCAGCCCAAC TGGGGGCCCA
    AGAGGACGTC TTAATGGCAC AGGAGGCCCT CGTGAATGTA ACAGCTTCCT CAGGCATGCC
    AGAGAAACCC CTGATTCCTA CCGAGACTCT CCTCATAGTG AAAGGTATGT GTCAGCCATG
    ACCACCCCGG CTCGTATGTC ACCTGTAGAT TTCCACACGC CAAGCTCCCC CAAATCGCCC
    CCTTCGGAAA TGTCTCCACC CGTGTCCAGC ATGACGGTGT CCATGCCTTC CATGGCGGTC
    AGCCCCTTCA TGGAAGAAGA GAGACCTCTA CTTCTCGTGA CACCACCAAG GCTGCGGGAG
    AAGAAGTTTG ACCATCACCC TCAGCAGTTC AGCTCCTTCC ACCACAACCC CGCGCATGAC
    AGTAACAGCC TCCCTGCTAG CCCCTTGAGG ATAGTGGAGG ATGAGGAGTA TGAAACGACC
    CAAGAGTACG AGCCAGCCCA AGAGCCTGTT AAGAAACTCG CCAATAGCCG GCGGGCCAAA
    AGAACCAAGC CCAATGGCCA CATTGCTAAC AGATTGGAAG TGGACAGCAA CACAAGCTCC
    CAGAGCAGTA ACTCAGAGAG TGAAACAGAA GATGAAAGAG TAGGTGAAGA TACGCCTTTC
    CTGGGCATAC AGAACCCCCT GGCAGCCAGT CTTGAGGCAA CACCTGCCTT CCGCCTGGCT
    GACAGCAGGA CTAACCCAGC AGGCCGCTTC TCGACACAGG AAGAAATCCA GGCCAGGCTG
    TCTAGTGTAA TTGCTAACCA AGACCCTATT GCTGTATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_011542814.1
    CDS280..2238
    Translation

    Target ORF information:

    RefSeq Version XM_011544512.2
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant X8, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_011544512.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    ATGGAGCCCG ACGCCAACAG CACCAGCCGC GCGCCGGCCG CCTTCCGAGC CTCTTTCCCC 
    CCTCTGGAGA CGGGCCGGAA CCTCAAGAAG GAGGTCAGCC GGGTGCTGTG CAAGCGGTGC
    GCCTTGCCTC CCCGATTGAA AGAGATGAAA AGCCAGGAAT CGGCTGCAGG TTCCAAACTA
    GTCCTTCGGT GTGAAACCAG TTCTGAATAC TCCTCTCTCA GATTCAAGTG GTTCAAGAAT
    GGGAATGAAT TGAATCGAAA AAACAAACCA CAAAATATCA AGATACAAAA AAAGCCAGGG
    AAGTCAGAAC TTCGCATTAA CAAAGCATCA CTGGCTGATT CTGGAGAGTA TATGTGCAAA
    GTGATCAGCA AATTAGGAAA TGACAGTGCC TCTGCCAATA TCACCATCGT GGAATCAAAC
    GAGATCATCA CTGGTATGCC AGCCTCAACT GAAGGAGCAT ATGTGTCTTC AGAGTCTCCC
    ATTAGAATAT CAGTATCCAC AGAAGGAGCA AATACTTCTT CATCTACATC TACATCCACC
    ACTGGGACAA GCCATCTTGT AAAATGTGCG GAGAAGGAGA AAACTTTCTG TGTGAATGGA
    GGGGAGTGCT TCATGGTGAA AGACCTTTCA AACCCCTCGA GATACTTGTG CAAGTGCCCA
    AATGAGTTTA CTGGTGATCG CTGCCAAAAC TACGTAATGG CCAGCTTCTA CAAGCATCTT
    GGGATTGAAT TTATGGAGGC GGAGGAGCTG TACCAGAAGA GAGTGCTGAC CATAACCGGC
    ATCTGCATCG CCCTCCTTGT GGTCGGCATC ATGTGTGTGG TGGCCTACTG CAAAACCAAG
    AAACAGCGGA AAAAGCTGCA TGACCGTCTT CGGCAGAGCC TTCGGTCTGA ACGAAACAAT
    ATGATGAACA TTGCCAATGG GCCTCACCAT CCTAACCCAC CCCCCGAGAA TGTCCAGCTG
    GTGAATCAAT ACGTATCTAA AAACGTCATC TCCAGTGAGC ATATTGTTGA GAGAGAAGCA
    GAGACATCCT TTTCCACCAG TCACTATACT TCCACAGCCC ATCACTCCAC TACTGTCACC
    CAGACTCCTA GCCACAGCTG GAGCAACGGA CACACTGAAA GCATCCTTTC CGAAAGCCAC
    TCTGTAATCG TGATGTCATC CGTAGAAAAC AGTAGGCACA GCAGCCCAAC TGGGGGCCCA
    AGAGGACGTC TTAATGGCAC AGGAGGCCCT CGTGAATGTA ACAGCTTCCT CAGGCATGCC
    AGAGAAACCC CTGATTCCTA CCGAGACTCT CCTCATAGTG AAAGGTATGT GTCAGCCATG
    ACCACCCCGG CTCGTATGTC ACCTGTAGAT TTCCACACGC CAAGCTCCCC CAAATCGCCC
    CCTTCGGAAA TGTCTCCACC CGTGTCCAGC ATGACGGTGT CCATGCCTTC CATGGCGGTC
    AGCCCCTTCA TGGAAGAAGA GAGACCTCTA CTTCTCGTGA CACCACCAAG GCTGCGGGAG
    AAGAAGTTTG ACCATCACCC TCAGCAGTTC AGCTCCTTCC ACCACAACCC CGCGCATGAC
    AGTAACAGCC TCCCTGCTAG CCCCTTGAGG ATAGTGGAGG ATGAGGAGTA TGAAACGACC
    CAAGAGTACG AGCCAGCCCA AGAGCCTGTT AAGAAACTCG CCAATAGCCG GCGGGCCAAA
    AGAACCAAGC CCAATGGCCA CATTGCTAAC AGATTGGAAG TGGACAGCAA CACAAGCTCC
    CAGAGCAGTA ACTCAGAGAG TGAAACAGAA GATGAAAGAG TAGGTGAAGA TACGCCTTTC
    CTGGGCATAC AGAACCCCCT GGCAGCCAGT CTTGAGGCAA CACCTGCCTT CCGCCTGGCT
    GACAGCAGGA CTAACCCAGC AGGCCGCTTC TCGACACAGG AAGAAATCCA GGCCAGGCTG
    TCTAGTGTAA TTGCTAACCA AGACCCTATT GCTGTATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu102686
    Clone ID Related Accession (Same CDS sequence) NM_001322207.1 , NM_001322207.2
    Accession Version NM_001322207.1 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1452bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2018-12-22
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform III-3
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK289927.1, M94166.1, BC144446.1, AC113209.4, AK298132.1 and BQ018711.1. Transcript Variant: This variant (III-3), which uses the type III promoter, lacks several 5' exons but contains an alternate 5' terminal exon and thus differs in the 5' UTR and 5' coding region, and it also contains an alternate 3' terminal exon that results in an early stop codon, compared to variant HRG-beta1. The resulting isoform (III-3) has distinct N- and C-termini and is shorter than isoform HRG-beta1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.196051.1, SRR5189652.250667.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    ATGGAGATTT ATTCCCCAGA CATGTCTGAG GTCGCCGCCG AGAGGTCCTC CAGCCCCTCC 
    ACTCAGCTGA GTGCAGACCC ATCTCTTGAT GGGCTTCCGG CAGCAGAAGA CATGCCAGAG
    CCCCAGACTG AAGATGGGAG AACCCCTGGA CTCGTGGGCC TGGCCGTGCC CTGCTGTGCG
    TGCCTAGAAG CTGAGCGCCT GAGAGGTTGC CTCAACTCAG AGAAAATCTG CATTGTCCCC
    ATCCTGGCTT GCCTGGTCAG CCTCTGCCTC TGCATCGCCG GCCTCAAGTG GGTATTTGTG
    GACAAGATCT TTGAATATGA CTCTCCTACT CACCTTGACC CTGGGGGGTT AGGCCAGGAC
    CCTATTATTT CTCTGGACGC AACTGCTGCC TCAGCTGTGT GGGTGTCGTC TGAGGCATAC
    ACTTCACCTG TCTCTAGGGC TCAATCTGAA AGTGAGGTTC AAGTTACAGT GCAAGGTGAC
    AAGGCTGTTG TCTCCTTTGA ACCATCAGCG GCACCGACAC CGAAGAATCG TATTTTTGCC
    TTTTCTTTCT TGCCGTCCAC TGCGCCATCC TTCCCTTCAC CCACCCGGAA CCCTGAGGTG
    AGAACGCCCA AGTCAGCAAC TCAGCCACAA ACAACAGAAA CTAATCTCCA AACTGCTCCT
    AAACTTTCTA CATCTACATC CACCACTGGG ACAAGCCATC TTGTAAAATG TGCGGAGAAG
    GAGAAAACTT TCTGTGTGAA TGGAGGGGAG TGCTTCATGG TGAAAGACCT TTCAAACCCC
    TCGAGATACT TGTGCAAGTG CCCAAATGAG TTTACTGGTG ATCGCTGCCA AAACTACGTA
    ATGGCCAGCT TCTACAAGCA TCTTGGGATT GAATTTATGG AGGCGGAGGA GCTGTACCAG
    AAGAGAGTGC TGACCATAAC CGGCATCTGC ATCGCCCTCC TTGTGGTCGG CATCATGTGT
    GTGGTGGCCT ACTGCAAAAC CAAGAAACAG CGGAAAAAGC TGCATGACCG TCTTCGGCAG
    AGCCTTCGGT CTGAACGAAA CAATATGATG AACATTGCCA ATGGGCCTCA CCATCCTAAC
    CCACCCCCCG AGAATGTCCA GCTGGTGAAT CAATACGTAT CTAAAAACGT CATCTCCAGT
    GAGCATATTG TTGAGAGAGA AGCAGAGACA TCCTTTTCCA CCAGTCACTA TACTTCCACA
    GCCCATCACT CCACTACTGT CACCCAGACT CCTAGCCACA GCTGGAGCAA CGGACACACT
    GAAAGCATCC TTTCCGAAAG CCACTCTGTA ATCGTGATGT CATCCGTAGA AAACAGTAGG
    CACAGCAGCC CAACTGGGGG CCCAAGAGGA CGTCTTAATG GCACAGGAGG CCCTCGTGAA
    TGTAACAGCT TCCTCAGGCA TGCCAGAGAA ACCCCTGATT CCTACCGAGA CTCTCCTCAT
    AGTGAAAGGT AA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001309136.1
    CDS987..2438
    Translation

    Target ORF information:

    RefSeq Version NM_001322207.1
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant III-3, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001322207.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    ATGGAGATTT ATTCCCCAGA CATGTCTGAG GTCGCCGCCG AGAGGTCCTC CAGCCCCTCC 
    ACTCAGCTGA GTGCAGACCC ATCTCTTGAT GGGCTTCCGG CAGCAGAAGA CATGCCAGAG
    CCCCAGACTG AAGATGGGAG AACCCCTGGA CTCGTGGGCC TGGCCGTGCC CTGCTGTGCG
    TGCCTAGAAG CTGAGCGCCT GAGAGGTTGC CTCAACTCAG AGAAAATCTG CATTGTCCCC
    ATCCTGGCTT GCCTGGTCAG CCTCTGCCTC TGCATCGCCG GCCTCAAGTG GGTATTTGTG
    GACAAGATCT TTGAATATGA CTCTCCTACT CACCTTGACC CTGGGGGGTT AGGCCAGGAC
    CCTATTATTT CTCTGGACGC AACTGCTGCC TCAGCTGTGT GGGTGTCGTC TGAGGCATAC
    ACTTCACCTG TCTCTAGGGC TCAATCTGAA AGTGAGGTTC AAGTTACAGT GCAAGGTGAC
    AAGGCTGTTG TCTCCTTTGA ACCATCAGCG GCACCGACAC CGAAGAATCG TATTTTTGCC
    TTTTCTTTCT TGCCGTCCAC TGCGCCATCC TTCCCTTCAC CCACCCGGAA CCCTGAGGTG
    AGAACGCCCA AGTCAGCAAC TCAGCCACAA ACAACAGAAA CTAATCTCCA AACTGCTCCT
    AAACTTTCTA CATCTACATC CACCACTGGG ACAAGCCATC TTGTAAAATG TGCGGAGAAG
    GAGAAAACTT TCTGTGTGAA TGGAGGGGAG TGCTTCATGG TGAAAGACCT TTCAAACCCC
    TCGAGATACT TGTGCAAGTG CCCAAATGAG TTTACTGGTG ATCGCTGCCA AAACTACGTA
    ATGGCCAGCT TCTACAAGCA TCTTGGGATT GAATTTATGG AGGCGGAGGA GCTGTACCAG
    AAGAGAGTGC TGACCATAAC CGGCATCTGC ATCGCCCTCC TTGTGGTCGG CATCATGTGT
    GTGGTGGCCT ACTGCAAAAC CAAGAAACAG CGGAAAAAGC TGCATGACCG TCTTCGGCAG
    AGCCTTCGGT CTGAACGAAA CAATATGATG AACATTGCCA ATGGGCCTCA CCATCCTAAC
    CCACCCCCCG AGAATGTCCA GCTGGTGAAT CAATACGTAT CTAAAAACGT CATCTCCAGT
    GAGCATATTG TTGAGAGAGA AGCAGAGACA TCCTTTTCCA CCAGTCACTA TACTTCCACA
    GCCCATCACT CCACTACTGT CACCCAGACT CCTAGCCACA GCTGGAGCAA CGGACACACT
    GAAAGCATCC TTTCCGAAAG CCACTCTGTA ATCGTGATGT CATCCGTAGA AAACAGTAGG
    CACAGCAGCC CAACTGGGGG CCCAAGAGGA CGTCTTAATG GCACAGGAGG CCCTCGTGAA
    TGTAACAGCT TCCTCAGGCA TGCCAGAGAA ACCCCTGATT CCTACCGAGA CTCTCCTCAT
    AGTGAAAGGT AA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu102686
    Clone ID Related Accession (Same CDS sequence) NM_001322207.1 , NM_001322207.2
    Accession Version NM_001322207.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1452bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-20
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform III-3
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK289927.1, M94166.1, BC144446.1, AC113209.4, AK298132.1 and BQ018711.1. On Jun 2, 2019 this sequence version replaced NM_001322207.1. Transcript Variant: This variant (III-3), which uses the type III promoter, lacks several 5' exons but contains an alternate 5' terminal exon and thus differs in the 5' UTR and 5' coding region, and it also contains an alternate 3' terminal exon that results in an early stop codon, compared to variant HRG-beta1. The resulting isoform (III-3) has distinct N- and C-termini and is shorter than isoform HRG-beta1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.196051.1, SRR5189652.250667.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    ATGGAGATTT ATTCCCCAGA CATGTCTGAG GTCGCCGCCG AGAGGTCCTC CAGCCCCTCC 
    ACTCAGCTGA GTGCAGACCC ATCTCTTGAT GGGCTTCCGG CAGCAGAAGA CATGCCAGAG
    CCCCAGACTG AAGATGGGAG AACCCCTGGA CTCGTGGGCC TGGCCGTGCC CTGCTGTGCG
    TGCCTAGAAG CTGAGCGCCT GAGAGGTTGC CTCAACTCAG AGAAAATCTG CATTGTCCCC
    ATCCTGGCTT GCCTGGTCAG CCTCTGCCTC TGCATCGCCG GCCTCAAGTG GGTATTTGTG
    GACAAGATCT TTGAATATGA CTCTCCTACT CACCTTGACC CTGGGGGGTT AGGCCAGGAC
    CCTATTATTT CTCTGGACGC AACTGCTGCC TCAGCTGTGT GGGTGTCGTC TGAGGCATAC
    ACTTCACCTG TCTCTAGGGC TCAATCTGAA AGTGAGGTTC AAGTTACAGT GCAAGGTGAC
    AAGGCTGTTG TCTCCTTTGA ACCATCAGCG GCACCGACAC CGAAGAATCG TATTTTTGCC
    TTTTCTTTCT TGCCGTCCAC TGCGCCATCC TTCCCTTCAC CCACCCGGAA CCCTGAGGTG
    AGAACGCCCA AGTCAGCAAC TCAGCCACAA ACAACAGAAA CTAATCTCCA AACTGCTCCT
    AAACTTTCTA CATCTACATC CACCACTGGG ACAAGCCATC TTGTAAAATG TGCGGAGAAG
    GAGAAAACTT TCTGTGTGAA TGGAGGGGAG TGCTTCATGG TGAAAGACCT TTCAAACCCC
    TCGAGATACT TGTGCAAGTG CCCAAATGAG TTTACTGGTG ATCGCTGCCA AAACTACGTA
    ATGGCCAGCT TCTACAAGCA TCTTGGGATT GAATTTATGG AGGCGGAGGA GCTGTACCAG
    AAGAGAGTGC TGACCATAAC CGGCATCTGC ATCGCCCTCC TTGTGGTCGG CATCATGTGT
    GTGGTGGCCT ACTGCAAAAC CAAGAAACAG CGGAAAAAGC TGCATGACCG TCTTCGGCAG
    AGCCTTCGGT CTGAACGAAA CAATATGATG AACATTGCCA ATGGGCCTCA CCATCCTAAC
    CCACCCCCCG AGAATGTCCA GCTGGTGAAT CAATACGTAT CTAAAAACGT CATCTCCAGT
    GAGCATATTG TTGAGAGAGA AGCAGAGACA TCCTTTTCCA CCAGTCACTA TACTTCCACA
    GCCCATCACT CCACTACTGT CACCCAGACT CCTAGCCACA GCTGGAGCAA CGGACACACT
    GAAAGCATCC TTTCCGAAAG CCACTCTGTA ATCGTGATGT CATCCGTAGA AAACAGTAGG
    CACAGCAGCC CAACTGGGGG CCCAAGAGGA CGTCTTAATG GCACAGGAGG CCCTCGTGAA
    TGTAACAGCT TCCTCAGGCA TGCCAGAGAA ACCCCTGATT CCTACCGAGA CTCTCCTCAT
    AGTGAAAGGT AA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001309136.1
    CDS630..2081
    Translation

    Target ORF information:

    RefSeq Version NM_001322207.2
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant III-3, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001322207.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    ATGGAGATTT ATTCCCCAGA CATGTCTGAG GTCGCCGCCG AGAGGTCCTC CAGCCCCTCC 
    ACTCAGCTGA GTGCAGACCC ATCTCTTGAT GGGCTTCCGG CAGCAGAAGA CATGCCAGAG
    CCCCAGACTG AAGATGGGAG AACCCCTGGA CTCGTGGGCC TGGCCGTGCC CTGCTGTGCG
    TGCCTAGAAG CTGAGCGCCT GAGAGGTTGC CTCAACTCAG AGAAAATCTG CATTGTCCCC
    ATCCTGGCTT GCCTGGTCAG CCTCTGCCTC TGCATCGCCG GCCTCAAGTG GGTATTTGTG
    GACAAGATCT TTGAATATGA CTCTCCTACT CACCTTGACC CTGGGGGGTT AGGCCAGGAC
    CCTATTATTT CTCTGGACGC AACTGCTGCC TCAGCTGTGT GGGTGTCGTC TGAGGCATAC
    ACTTCACCTG TCTCTAGGGC TCAATCTGAA AGTGAGGTTC AAGTTACAGT GCAAGGTGAC
    AAGGCTGTTG TCTCCTTTGA ACCATCAGCG GCACCGACAC CGAAGAATCG TATTTTTGCC
    TTTTCTTTCT TGCCGTCCAC TGCGCCATCC TTCCCTTCAC CCACCCGGAA CCCTGAGGTG
    AGAACGCCCA AGTCAGCAAC TCAGCCACAA ACAACAGAAA CTAATCTCCA AACTGCTCCT
    AAACTTTCTA CATCTACATC CACCACTGGG ACAAGCCATC TTGTAAAATG TGCGGAGAAG
    GAGAAAACTT TCTGTGTGAA TGGAGGGGAG TGCTTCATGG TGAAAGACCT TTCAAACCCC
    TCGAGATACT TGTGCAAGTG CCCAAATGAG TTTACTGGTG ATCGCTGCCA AAACTACGTA
    ATGGCCAGCT TCTACAAGCA TCTTGGGATT GAATTTATGG AGGCGGAGGA GCTGTACCAG
    AAGAGAGTGC TGACCATAAC CGGCATCTGC ATCGCCCTCC TTGTGGTCGG CATCATGTGT
    GTGGTGGCCT ACTGCAAAAC CAAGAAACAG CGGAAAAAGC TGCATGACCG TCTTCGGCAG
    AGCCTTCGGT CTGAACGAAA CAATATGATG AACATTGCCA ATGGGCCTCA CCATCCTAAC
    CCACCCCCCG AGAATGTCCA GCTGGTGAAT CAATACGTAT CTAAAAACGT CATCTCCAGT
    GAGCATATTG TTGAGAGAGA AGCAGAGACA TCCTTTTCCA CCAGTCACTA TACTTCCACA
    GCCCATCACT CCACTACTGT CACCCAGACT CCTAGCCACA GCTGGAGCAA CGGACACACT
    GAAAGCATCC TTTCCGAAAG CCACTCTGTA ATCGTGATGT CATCCGTAGA AAACAGTAGG
    CACAGCAGCC CAACTGGGGG CCCAAGAGGA CGTCTTAATG GCACAGGAGG CCCTCGTGAA
    TGTAACAGCT TCCTCAGGCA TGCCAGAGAA ACCCCTGATT CCTACCGAGA CTCTCCTCAT
    AGTGAAAGGT AA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu102719
    Clone ID Related Accession (Same CDS sequence) NM_001322197.1 , NM_001322197.2
    Accession Version NM_001322197.1 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1452bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2018-12-22
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform VI-1
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CN603661.1, AK293270.1, AC113209.4 and CA429204.1. Transcript Variant: This variant (VI-1), which uses the type VI promoter, lacks multiple 5' exons but contains an alternate 5' terminal exon and thus differs in the 5' UTR and 5' coding region, and it also lacks an in-frame exon in the central coding region, compared to variant HRG-beta1. The resulting isoform (VI-1) has a distinct N-terminus, lacks an internal segment, and is shorter than isoform HRG-beta1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK293270.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145240, SAMN03465403 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    ATGCAGATTC CTAAACACAT AAGCATTGAA GATATTACAG CTACATCTAC ATCCACCACT 
    GGGACAAGCC ATCTTGTAAA ATGTGCGGAG AAGGAGAAAA CTTTCTGTGT GAATGGAGGG
    GAGTGCTTCA TGGTGAAAGA CCTTTCAAAC CCCTCGAGAT ACTTGTGCAA GTGCCCAAAT
    GAGTTTACTG GTGATCGCTG CCAAAACTAC GTAATGGCCA GCTTCTACAA GGCGGAGGAG
    CTGTACCAGA AGAGAGTGCT GACCATAACC GGCATCTGCA TCGCCCTCCT TGTGGTCGGC
    ATCATGTGTG TGGTGGCCTA CTGCAAAACC AAGAAACAGC GGAAAAAGCT GCATGACCGT
    CTTCGGCAGA GCCTTCGGTC TGAACGAAAC AATATGATGA ACATTGCCAA TGGGCCTCAC
    CATCCTAACC CACCCCCCGA GAATGTCCAG CTGGTGAATC AATACGTATC TAAAAACGTC
    ATCTCCAGTG AGCATATTGT TGAGAGAGAA GCAGAGACAT CCTTTTCCAC CAGTCACTAT
    ACTTCCACAG CCCATCACTC CACTACTGTC ACCCAGACTC CTAGCCACAG CTGGAGCAAC
    GGACACACTG AAAGCATCCT TTCCGAAAGC CACTCTGTAA TCGTGATGTC ATCCGTAGAA
    AACAGTAGGC ACAGCAGCCC AACTGGGGGC CCAAGAGGAC GTCTTAATGG CACAGGAGGC
    CCTCGTGAAT GTAACAGCTT CCTCAGGCAT GCCAGAGAAA CCCCTGATTC CTACCGAGAC
    TCTCCTCATA GTGAAAGGTA TGTGTCAGCC ATGACCACCC CGGCTCGTAT GTCACCTGTA
    GATTTCCACA CGCCAAGCTC CCCCAAATCG CCCCCTTCGG AAATGTCTCC ACCCGTGTCC
    AGCATGACGG TGTCCATGCC TTCCATGGCG GTCAGCCCCT TCATGGAAGA AGAGAGACCT
    CTACTTCTCG TGACACCACC AAGGCTGCGG GAGAAGAAGT TTGACCATCA CCCTCAGCAG
    TTCAGCTCCT TCCACCACAA CCCCGCGCAT GACAGTAACA GCCTCCCTGC TAGCCCCTTG
    AGGATAGTGG AGGATGAGGA GTATGAAACG ACCCAAGAGT ACGAGCCAGC CCAAGAGCCT
    GTTAAGAAAC TCGCCAATAG CCGGCGGGCC AAAAGAACCA AGCCCAATGG CCACATTGCT
    AACAGATTGG AAGTGGACAG CAACACAAGC TCCCAGAGCA GTAACTCAGA GAGTGAAACA
    GAAGATGAAA GAGTAGGTGA AGATACGCCT TTCCTGGGCA TACAGAACCC CCTGGCAGCC
    AGTCTTGAGG CAACACCTGC CTTCCGCCTG GCTGACAGCA GGACTAACCC AGCAGGCCGC
    TTCTCGACAC AGGAAGAAAT CCAGGCCAGG CTGTCTAGTG TAATTGCTAA CCAAGACCCT
    ATTGCTGTAT AA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001309126.1
    CDS251..1702
    Translation

    Target ORF information:

    RefSeq Version NM_001322197.1
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant VI-1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001322197.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    ATGCAGATTC CTAAACACAT AAGCATTGAA GATATTACAG CTACATCTAC ATCCACCACT 
    GGGACAAGCC ATCTTGTAAA ATGTGCGGAG AAGGAGAAAA CTTTCTGTGT GAATGGAGGG
    GAGTGCTTCA TGGTGAAAGA CCTTTCAAAC CCCTCGAGAT ACTTGTGCAA GTGCCCAAAT
    GAGTTTACTG GTGATCGCTG CCAAAACTAC GTAATGGCCA GCTTCTACAA GGCGGAGGAG
    CTGTACCAGA AGAGAGTGCT GACCATAACC GGCATCTGCA TCGCCCTCCT TGTGGTCGGC
    ATCATGTGTG TGGTGGCCTA CTGCAAAACC AAGAAACAGC GGAAAAAGCT GCATGACCGT
    CTTCGGCAGA GCCTTCGGTC TGAACGAAAC AATATGATGA ACATTGCCAA TGGGCCTCAC
    CATCCTAACC CACCCCCCGA GAATGTCCAG CTGGTGAATC AATACGTATC TAAAAACGTC
    ATCTCCAGTG AGCATATTGT TGAGAGAGAA GCAGAGACAT CCTTTTCCAC CAGTCACTAT
    ACTTCCACAG CCCATCACTC CACTACTGTC ACCCAGACTC CTAGCCACAG CTGGAGCAAC
    GGACACACTG AAAGCATCCT TTCCGAAAGC CACTCTGTAA TCGTGATGTC ATCCGTAGAA
    AACAGTAGGC ACAGCAGCCC AACTGGGGGC CCAAGAGGAC GTCTTAATGG CACAGGAGGC
    CCTCGTGAAT GTAACAGCTT CCTCAGGCAT GCCAGAGAAA CCCCTGATTC CTACCGAGAC
    TCTCCTCATA GTGAAAGGTA TGTGTCAGCC ATGACCACCC CGGCTCGTAT GTCACCTGTA
    GATTTCCACA CGCCAAGCTC CCCCAAATCG CCCCCTTCGG AAATGTCTCC ACCCGTGTCC
    AGCATGACGG TGTCCATGCC TTCCATGGCG GTCAGCCCCT TCATGGAAGA AGAGAGACCT
    CTACTTCTCG TGACACCACC AAGGCTGCGG GAGAAGAAGT TTGACCATCA CCCTCAGCAG
    TTCAGCTCCT TCCACCACAA CCCCGCGCAT GACAGTAACA GCCTCCCTGC TAGCCCCTTG
    AGGATAGTGG AGGATGAGGA GTATGAAACG ACCCAAGAGT ACGAGCCAGC CCAAGAGCCT
    GTTAAGAAAC TCGCCAATAG CCGGCGGGCC AAAAGAACCA AGCCCAATGG CCACATTGCT
    AACAGATTGG AAGTGGACAG CAACACAAGC TCCCAGAGCA GTAACTCAGA GAGTGAAACA
    GAAGATGAAA GAGTAGGTGA AGATACGCCT TTCCTGGGCA TACAGAACCC CCTGGCAGCC
    AGTCTTGAGG CAACACCTGC CTTCCGCCTG GCTGACAGCA GGACTAACCC AGCAGGCCGC
    TTCTCGACAC AGGAAGAAAT CCAGGCCAGG CTGTCTAGTG TAATTGCTAA CCAAGACCCT
    ATTGCTGTAT AA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu102719
    Clone ID Related Accession (Same CDS sequence) NM_001322197.1 , NM_001322197.2
    Accession Version NM_001322197.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1452bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-20
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform VI-1
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CN603661.1, AK293270.1, AC113209.4 and CA429204.1. On Jun 2, 2019 this sequence version replaced NM_001322197.1. Transcript Variant: This variant (VI-1), which uses the type VI promoter, lacks multiple 5' exons but contains an alternate 5' terminal exon and thus differs in the 5' UTR and 5' coding region, and it also lacks an in-frame exon in the central coding region, compared to variant HRG-beta1. The resulting isoform (VI-1) has a distinct N-terminus, lacks an internal segment, and is shorter than isoform HRG-beta1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK293270.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145240, SAMN03465403 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    ATGCAGATTC CTAAACACAT AAGCATTGAA GATATTACAG CTACATCTAC ATCCACCACT 
    GGGACAAGCC ATCTTGTAAA ATGTGCGGAG AAGGAGAAAA CTTTCTGTGT GAATGGAGGG
    GAGTGCTTCA TGGTGAAAGA CCTTTCAAAC CCCTCGAGAT ACTTGTGCAA GTGCCCAAAT
    GAGTTTACTG GTGATCGCTG CCAAAACTAC GTAATGGCCA GCTTCTACAA GGCGGAGGAG
    CTGTACCAGA AGAGAGTGCT GACCATAACC GGCATCTGCA TCGCCCTCCT TGTGGTCGGC
    ATCATGTGTG TGGTGGCCTA CTGCAAAACC AAGAAACAGC GGAAAAAGCT GCATGACCGT
    CTTCGGCAGA GCCTTCGGTC TGAACGAAAC AATATGATGA ACATTGCCAA TGGGCCTCAC
    CATCCTAACC CACCCCCCGA GAATGTCCAG CTGGTGAATC AATACGTATC TAAAAACGTC
    ATCTCCAGTG AGCATATTGT TGAGAGAGAA GCAGAGACAT CCTTTTCCAC CAGTCACTAT
    ACTTCCACAG CCCATCACTC CACTACTGTC ACCCAGACTC CTAGCCACAG CTGGAGCAAC
    GGACACACTG AAAGCATCCT TTCCGAAAGC CACTCTGTAA TCGTGATGTC ATCCGTAGAA
    AACAGTAGGC ACAGCAGCCC AACTGGGGGC CCAAGAGGAC GTCTTAATGG CACAGGAGGC
    CCTCGTGAAT GTAACAGCTT CCTCAGGCAT GCCAGAGAAA CCCCTGATTC CTACCGAGAC
    TCTCCTCATA GTGAAAGGTA TGTGTCAGCC ATGACCACCC CGGCTCGTAT GTCACCTGTA
    GATTTCCACA CGCCAAGCTC CCCCAAATCG CCCCCTTCGG AAATGTCTCC ACCCGTGTCC
    AGCATGACGG TGTCCATGCC TTCCATGGCG GTCAGCCCCT TCATGGAAGA AGAGAGACCT
    CTACTTCTCG TGACACCACC AAGGCTGCGG GAGAAGAAGT TTGACCATCA CCCTCAGCAG
    TTCAGCTCCT TCCACCACAA CCCCGCGCAT GACAGTAACA GCCTCCCTGC TAGCCCCTTG
    AGGATAGTGG AGGATGAGGA GTATGAAACG ACCCAAGAGT ACGAGCCAGC CCAAGAGCCT
    GTTAAGAAAC TCGCCAATAG CCGGCGGGCC AAAAGAACCA AGCCCAATGG CCACATTGCT
    AACAGATTGG AAGTGGACAG CAACACAAGC TCCCAGAGCA GTAACTCAGA GAGTGAAACA
    GAAGATGAAA GAGTAGGTGA AGATACGCCT TTCCTGGGCA TACAGAACCC CCTGGCAGCC
    AGTCTTGAGG CAACACCTGC CTTCCGCCTG GCTGACAGCA GGACTAACCC AGCAGGCCGC
    TTCTCGACAC AGGAAGAAAT CCAGGCCAGG CTGTCTAGTG TAATTGCTAA CCAAGACCCT
    ATTGCTGTAT AA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001309126.1
    CDS169..1620
    Translation

    Target ORF information:

    RefSeq Version NM_001322197.2
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant VI-1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001322197.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    ATGCAGATTC CTAAACACAT AAGCATTGAA GATATTACAG CTACATCTAC ATCCACCACT 
    GGGACAAGCC ATCTTGTAAA ATGTGCGGAG AAGGAGAAAA CTTTCTGTGT GAATGGAGGG
    GAGTGCTTCA TGGTGAAAGA CCTTTCAAAC CCCTCGAGAT ACTTGTGCAA GTGCCCAAAT
    GAGTTTACTG GTGATCGCTG CCAAAACTAC GTAATGGCCA GCTTCTACAA GGCGGAGGAG
    CTGTACCAGA AGAGAGTGCT GACCATAACC GGCATCTGCA TCGCCCTCCT TGTGGTCGGC
    ATCATGTGTG TGGTGGCCTA CTGCAAAACC AAGAAACAGC GGAAAAAGCT GCATGACCGT
    CTTCGGCAGA GCCTTCGGTC TGAACGAAAC AATATGATGA ACATTGCCAA TGGGCCTCAC
    CATCCTAACC CACCCCCCGA GAATGTCCAG CTGGTGAATC AATACGTATC TAAAAACGTC
    ATCTCCAGTG AGCATATTGT TGAGAGAGAA GCAGAGACAT CCTTTTCCAC CAGTCACTAT
    ACTTCCACAG CCCATCACTC CACTACTGTC ACCCAGACTC CTAGCCACAG CTGGAGCAAC
    GGACACACTG AAAGCATCCT TTCCGAAAGC CACTCTGTAA TCGTGATGTC ATCCGTAGAA
    AACAGTAGGC ACAGCAGCCC AACTGGGGGC CCAAGAGGAC GTCTTAATGG CACAGGAGGC
    CCTCGTGAAT GTAACAGCTT CCTCAGGCAT GCCAGAGAAA CCCCTGATTC CTACCGAGAC
    TCTCCTCATA GTGAAAGGTA TGTGTCAGCC ATGACCACCC CGGCTCGTAT GTCACCTGTA
    GATTTCCACA CGCCAAGCTC CCCCAAATCG CCCCCTTCGG AAATGTCTCC ACCCGTGTCC
    AGCATGACGG TGTCCATGCC TTCCATGGCG GTCAGCCCCT TCATGGAAGA AGAGAGACCT
    CTACTTCTCG TGACACCACC AAGGCTGCGG GAGAAGAAGT TTGACCATCA CCCTCAGCAG
    TTCAGCTCCT TCCACCACAA CCCCGCGCAT GACAGTAACA GCCTCCCTGC TAGCCCCTTG
    AGGATAGTGG AGGATGAGGA GTATGAAACG ACCCAAGAGT ACGAGCCAGC CCAAGAGCCT
    GTTAAGAAAC TCGCCAATAG CCGGCGGGCC AAAAGAACCA AGCCCAATGG CCACATTGCT
    AACAGATTGG AAGTGGACAG CAACACAAGC TCCCAGAGCA GTAACTCAGA GAGTGAAACA
    GAAGATGAAA GAGTAGGTGA AGATACGCCT TTCCTGGGCA TACAGAACCC CCTGGCAGCC
    AGTCTTGAGG CAACACCTGC CTTCCGCCTG GCTGACAGCA GGACTAACCC AGCAGGCCGC
    TTCTCGACAC AGGAAGAAAT CCAGGCCAGG CTGTCTAGTG TAATTGCTAA CCAAGACCCT
    ATTGCTGTAT AA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu97937
    Clone ID Related Accession (Same CDS sequence) XM_017013369.1 , XM_017013369.2
    Accession Version XM_017013369.1 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1476bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2016-06-05
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform X8
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    ATGCAGATTC CTAAACACAT AAGCATTGAA GATATTACAG CTACATCTAC ATCCACCACT 
    GGGACAAGCC ATCTTGTAAA ATGTGCGGAG AAGGAGAAAA CTTTCTGTGT GAATGGAGGG
    GAGTGCTTCA TGGTGAAAGA CCTTTCAAAC CCCTCGAGAT ACTTGTGCAA GTGCCCAAAT
    GAGTTTACTG GTGATCGCTG CCAAAACTAC GTAATGGCCA GCTTCTACAA GCATCTTGGG
    ATTGAATTTA TGGAGGCGGA GGAGCTGTAC CAGAAGAGAG TGCTGACCAT AACCGGCATC
    TGCATCGCCC TCCTTGTGGT CGGCATCATG TGTGTGGTGG CCTACTGCAA AACCAAGAAA
    CAGCGGAAAA AGCTGCATGA CCGTCTTCGG CAGAGCCTTC GGTCTGAACG AAACAATATG
    ATGAACATTG CCAATGGGCC TCACCATCCT AACCCACCCC CCGAGAATGT CCAGCTGGTG
    AATCAATACG TATCTAAAAA CGTCATCTCC AGTGAGCATA TTGTTGAGAG AGAAGCAGAG
    ACATCCTTTT CCACCAGTCA CTATACTTCC ACAGCCCATC ACTCCACTAC TGTCACCCAG
    ACTCCTAGCC ACAGCTGGAG CAACGGACAC ACTGAAAGCA TCCTTTCCGA AAGCCACTCT
    GTAATCGTGA TGTCATCCGT AGAAAACAGT AGGCACAGCA GCCCAACTGG GGGCCCAAGA
    GGACGTCTTA ATGGCACAGG AGGCCCTCGT GAATGTAACA GCTTCCTCAG GCATGCCAGA
    GAAACCCCTG ATTCCTACCG AGACTCTCCT CATAGTGAAA GGTATGTGTC AGCCATGACC
    ACCCCGGCTC GTATGTCACC TGTAGATTTC CACACGCCAA GCTCCCCCAA ATCGCCCCCT
    TCGGAAATGT CTCCACCCGT GTCCAGCATG ACGGTGTCCA TGCCTTCCAT GGCGGTCAGC
    CCCTTCATGG AAGAAGAGAG ACCTCTACTT CTCGTGACAC CACCAAGGCT GCGGGAGAAG
    AAGTTTGACC ATCACCCTCA GCAGTTCAGC TCCTTCCACC ACAACCCCGC GCATGACAGT
    AACAGCCTCC CTGCTAGCCC CTTGAGGATA GTGGAGGATG AGGAGTATGA AACGACCCAA
    GAGTACGAGC CAGCCCAAGA GCCTGTTAAG AAACTCGCCA ATAGCCGGCG GGCCAAAAGA
    ACCAAGCCCA ATGGCCACAT TGCTAACAGA TTGGAAGTGG ACAGCAACAC AAGCTCCCAG
    AGCAGTAACT CAGAGAGTGA AACAGAAGAT GAAAGAGTAG GTGAAGATAC GCCTTTCCTG
    GGCATACAGA ACCCCCTGGC AGCCAGTCTT GAGGCAACAC CTGCCTTCCG CCTGGCTGAC
    AGCAGGACTA ACCCAGCAGG CCGCTTCTCG ACACAGGAAG AAATCCAGGC CAGGCTGTCT
    AGTGTAATTG CTAACCAAGA CCCTATTGCT GTATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_016868858.1
    CDS1582..3057
    Translation

    Target ORF information:

    RefSeq Version XM_017013369.1
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant X8, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_017013369.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    ATGCAGATTC CTAAACACAT AAGCATTGAA GATATTACAG CTACATCTAC ATCCACCACT 
    GGGACAAGCC ATCTTGTAAA ATGTGCGGAG AAGGAGAAAA CTTTCTGTGT GAATGGAGGG
    GAGTGCTTCA TGGTGAAAGA CCTTTCAAAC CCCTCGAGAT ACTTGTGCAA GTGCCCAAAT
    GAGTTTACTG GTGATCGCTG CCAAAACTAC GTAATGGCCA GCTTCTACAA GCATCTTGGG
    ATTGAATTTA TGGAGGCGGA GGAGCTGTAC CAGAAGAGAG TGCTGACCAT AACCGGCATC
    TGCATCGCCC TCCTTGTGGT CGGCATCATG TGTGTGGTGG CCTACTGCAA AACCAAGAAA
    CAGCGGAAAA AGCTGCATGA CCGTCTTCGG CAGAGCCTTC GGTCTGAACG AAACAATATG
    ATGAACATTG CCAATGGGCC TCACCATCCT AACCCACCCC CCGAGAATGT CCAGCTGGTG
    AATCAATACG TATCTAAAAA CGTCATCTCC AGTGAGCATA TTGTTGAGAG AGAAGCAGAG
    ACATCCTTTT CCACCAGTCA CTATACTTCC ACAGCCCATC ACTCCACTAC TGTCACCCAG
    ACTCCTAGCC ACAGCTGGAG CAACGGACAC ACTGAAAGCA TCCTTTCCGA AAGCCACTCT
    GTAATCGTGA TGTCATCCGT AGAAAACAGT AGGCACAGCA GCCCAACTGG GGGCCCAAGA
    GGACGTCTTA ATGGCACAGG AGGCCCTCGT GAATGTAACA GCTTCCTCAG GCATGCCAGA
    GAAACCCCTG ATTCCTACCG AGACTCTCCT CATAGTGAAA GGTATGTGTC AGCCATGACC
    ACCCCGGCTC GTATGTCACC TGTAGATTTC CACACGCCAA GCTCCCCCAA ATCGCCCCCT
    TCGGAAATGT CTCCACCCGT GTCCAGCATG ACGGTGTCCA TGCCTTCCAT GGCGGTCAGC
    CCCTTCATGG AAGAAGAGAG ACCTCTACTT CTCGTGACAC CACCAAGGCT GCGGGAGAAG
    AAGTTTGACC ATCACCCTCA GCAGTTCAGC TCCTTCCACC ACAACCCCGC GCATGACAGT
    AACAGCCTCC CTGCTAGCCC CTTGAGGATA GTGGAGGATG AGGAGTATGA AACGACCCAA
    GAGTACGAGC CAGCCCAAGA GCCTGTTAAG AAACTCGCCA ATAGCCGGCG GGCCAAAAGA
    ACCAAGCCCA ATGGCCACAT TGCTAACAGA TTGGAAGTGG ACAGCAACAC AAGCTCCCAG
    AGCAGTAACT CAGAGAGTGA AACAGAAGAT GAAAGAGTAG GTGAAGATAC GCCTTTCCTG
    GGCATACAGA ACCCCCTGGC AGCCAGTCTT GAGGCAACAC CTGCCTTCCG CCTGGCTGAC
    AGCAGGACTA ACCCAGCAGG CCGCTTCTCG ACACAGGAAG AAATCCAGGC CAGGCTGTCT
    AGTGTAATTG CTAACCAAGA CCCTATTGCT GTATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu97937
    Clone ID Related Accession (Same CDS sequence) XM_017013369.1 , XM_017013369.2
    Accession Version XM_017013369.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1476bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-05
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform X9
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017013369.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    ATGCAGATTC CTAAACACAT AAGCATTGAA GATATTACAG CTACATCTAC ATCCACCACT 
    GGGACAAGCC ATCTTGTAAA ATGTGCGGAG AAGGAGAAAA CTTTCTGTGT GAATGGAGGG
    GAGTGCTTCA TGGTGAAAGA CCTTTCAAAC CCCTCGAGAT ACTTGTGCAA GTGCCCAAAT
    GAGTTTACTG GTGATCGCTG CCAAAACTAC GTAATGGCCA GCTTCTACAA GCATCTTGGG
    ATTGAATTTA TGGAGGCGGA GGAGCTGTAC CAGAAGAGAG TGCTGACCAT AACCGGCATC
    TGCATCGCCC TCCTTGTGGT CGGCATCATG TGTGTGGTGG CCTACTGCAA AACCAAGAAA
    CAGCGGAAAA AGCTGCATGA CCGTCTTCGG CAGAGCCTTC GGTCTGAACG AAACAATATG
    ATGAACATTG CCAATGGGCC TCACCATCCT AACCCACCCC CCGAGAATGT CCAGCTGGTG
    AATCAATACG TATCTAAAAA CGTCATCTCC AGTGAGCATA TTGTTGAGAG AGAAGCAGAG
    ACATCCTTTT CCACCAGTCA CTATACTTCC ACAGCCCATC ACTCCACTAC TGTCACCCAG
    ACTCCTAGCC ACAGCTGGAG CAACGGACAC ACTGAAAGCA TCCTTTCCGA AAGCCACTCT
    GTAATCGTGA TGTCATCCGT AGAAAACAGT AGGCACAGCA GCCCAACTGG GGGCCCAAGA
    GGACGTCTTA ATGGCACAGG AGGCCCTCGT GAATGTAACA GCTTCCTCAG GCATGCCAGA
    GAAACCCCTG ATTCCTACCG AGACTCTCCT CATAGTGAAA GGTATGTGTC AGCCATGACC
    ACCCCGGCTC GTATGTCACC TGTAGATTTC CACACGCCAA GCTCCCCCAA ATCGCCCCCT
    TCGGAAATGT CTCCACCCGT GTCCAGCATG ACGGTGTCCA TGCCTTCCAT GGCGGTCAGC
    CCCTTCATGG AAGAAGAGAG ACCTCTACTT CTCGTGACAC CACCAAGGCT GCGGGAGAAG
    AAGTTTGACC ATCACCCTCA GCAGTTCAGC TCCTTCCACC ACAACCCCGC GCATGACAGT
    AACAGCCTCC CTGCTAGCCC CTTGAGGATA GTGGAGGATG AGGAGTATGA AACGACCCAA
    GAGTACGAGC CAGCCCAAGA GCCTGTTAAG AAACTCGCCA ATAGCCGGCG GGCCAAAAGA
    ACCAAGCCCA ATGGCCACAT TGCTAACAGA TTGGAAGTGG ACAGCAACAC AAGCTCCCAG
    AGCAGTAACT CAGAGAGTGA AACAGAAGAT GAAAGAGTAG GTGAAGATAC GCCTTTCCTG
    GGCATACAGA ACCCCCTGGC AGCCAGTCTT GAGGCAACAC CTGCCTTCCG CCTGGCTGAC
    AGCAGGACTA ACCCAGCAGG CCGCTTCTCG ACACAGGAAG AAATCCAGGC CAGGCTGTCT
    AGTGTAATTG CTAACCAAGA CCCTATTGCT GTATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_016868858.1
    CDS1583..3058
    Translation

    Target ORF information:

    RefSeq Version XM_017013369.2
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant X9, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_017013369.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    ATGCAGATTC CTAAACACAT AAGCATTGAA GATATTACAG CTACATCTAC ATCCACCACT 
    GGGACAAGCC ATCTTGTAAA ATGTGCGGAG AAGGAGAAAA CTTTCTGTGT GAATGGAGGG
    GAGTGCTTCA TGGTGAAAGA CCTTTCAAAC CCCTCGAGAT ACTTGTGCAA GTGCCCAAAT
    GAGTTTACTG GTGATCGCTG CCAAAACTAC GTAATGGCCA GCTTCTACAA GCATCTTGGG
    ATTGAATTTA TGGAGGCGGA GGAGCTGTAC CAGAAGAGAG TGCTGACCAT AACCGGCATC
    TGCATCGCCC TCCTTGTGGT CGGCATCATG TGTGTGGTGG CCTACTGCAA AACCAAGAAA
    CAGCGGAAAA AGCTGCATGA CCGTCTTCGG CAGAGCCTTC GGTCTGAACG AAACAATATG
    ATGAACATTG CCAATGGGCC TCACCATCCT AACCCACCCC CCGAGAATGT CCAGCTGGTG
    AATCAATACG TATCTAAAAA CGTCATCTCC AGTGAGCATA TTGTTGAGAG AGAAGCAGAG
    ACATCCTTTT CCACCAGTCA CTATACTTCC ACAGCCCATC ACTCCACTAC TGTCACCCAG
    ACTCCTAGCC ACAGCTGGAG CAACGGACAC ACTGAAAGCA TCCTTTCCGA AAGCCACTCT
    GTAATCGTGA TGTCATCCGT AGAAAACAGT AGGCACAGCA GCCCAACTGG GGGCCCAAGA
    GGACGTCTTA ATGGCACAGG AGGCCCTCGT GAATGTAACA GCTTCCTCAG GCATGCCAGA
    GAAACCCCTG ATTCCTACCG AGACTCTCCT CATAGTGAAA GGTATGTGTC AGCCATGACC
    ACCCCGGCTC GTATGTCACC TGTAGATTTC CACACGCCAA GCTCCCCCAA ATCGCCCCCT
    TCGGAAATGT CTCCACCCGT GTCCAGCATG ACGGTGTCCA TGCCTTCCAT GGCGGTCAGC
    CCCTTCATGG AAGAAGAGAG ACCTCTACTT CTCGTGACAC CACCAAGGCT GCGGGAGAAG
    AAGTTTGACC ATCACCCTCA GCAGTTCAGC TCCTTCCACC ACAACCCCGC GCATGACAGT
    AACAGCCTCC CTGCTAGCCC CTTGAGGATA GTGGAGGATG AGGAGTATGA AACGACCCAA
    GAGTACGAGC CAGCCCAAGA GCCTGTTAAG AAACTCGCCA ATAGCCGGCG GGCCAAAAGA
    ACCAAGCCCA ATGGCCACAT TGCTAACAGA TTGGAAGTGG ACAGCAACAC AAGCTCCCAG
    AGCAGTAACT CAGAGAGTGA AACAGAAGAT GAAAGAGTAG GTGAAGATAC GCCTTTCCTG
    GGCATACAGA ACCCCCTGGC AGCCAGTCTT GAGGCAACAC CTGCCTTCCG CCTGGCTGAC
    AGCAGGACTA ACCCAGCAGG CCGCTTCTCG ACACAGGAAG AAATCCAGGC CAGGCTGTCT
    AGTGTAATTG CTAACCAAGA CCCTATTGCT GTATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu97938
    Clone ID Related Accession (Same CDS sequence) XM_017013370.1
    Accession Version XM_017013370.1 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1461bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-05
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform X10
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    ATGCAGATTC CTAAACACAT AAGCATTGAA GATATTACAG CTACATCTAC ATCCACCACT 
    GGGACAAGCC ATCTTGTAAA ATGTGCGGAG AAGGAGAAAA CTTTCTGTGT GAATGGAGGG
    GAGTGCTTCA TGGTGAAAGA CCTTTCAAAC CCCTCGAGAT ACTTGTGCAA GTGCCAACCT
    GGATTCACTG GAGCAAGATG TACTGAGAAT GTGCCCATGA AAGTCCAAAA CCAAGAAAAG
    GCGGAGGAGC TGTACCAGAA GAGAGTGCTG ACCATAACCG GCATCTGCAT CGCCCTCCTT
    GTGGTCGGCA TCATGTGTGT GGTGGCCTAC TGCAAAACCA AGAAACAGCG GAAAAAGCTG
    CATGACCGTC TTCGGCAGAG CCTTCGGTCT GAACGAAACA ATATGATGAA CATTGCCAAT
    GGGCCTCACC ATCCTAACCC ACCCCCCGAG AATGTCCAGC TGGTGAATCA ATACGTATCT
    AAAAACGTCA TCTCCAGTGA GCATATTGTT GAGAGAGAAG CAGAGACATC CTTTTCCACC
    AGTCACTATA CTTCCACAGC CCATCACTCC ACTACTGTCA CCCAGACTCC TAGCCACAGC
    TGGAGCAACG GACACACTGA AAGCATCCTT TCCGAAAGCC ACTCTGTAAT CGTGATGTCA
    TCCGTAGAAA ACAGTAGGCA CAGCAGCCCA ACTGGGGGCC CAAGAGGACG TCTTAATGGC
    ACAGGAGGCC CTCGTGAATG TAACAGCTTC CTCAGGCATG CCAGAGAAAC CCCTGATTCC
    TACCGAGACT CTCCTCATAG TGAAAGGTAT GTGTCAGCCA TGACCACCCC GGCTCGTATG
    TCACCTGTAG ATTTCCACAC GCCAAGCTCC CCCAAATCGC CCCCTTCGGA AATGTCTCCA
    CCCGTGTCCA GCATGACGGT GTCCATGCCT TCCATGGCGG TCAGCCCCTT CATGGAAGAA
    GAGAGACCTC TACTTCTCGT GACACCACCA AGGCTGCGGG AGAAGAAGTT TGACCATCAC
    CCTCAGCAGT TCAGCTCCTT CCACCACAAC CCCGCGCATG ACAGTAACAG CCTCCCTGCT
    AGCCCCTTGA GGATAGTGGA GGATGAGGAG TATGAAACGA CCCAAGAGTA CGAGCCAGCC
    CAAGAGCCTG TTAAGAAACT CGCCAATAGC CGGCGGGCCA AAAGAACCAA GCCCAATGGC
    CACATTGCTA ACAGATTGGA AGTGGACAGC AACACAAGCT CCCAGAGCAG TAACTCAGAG
    AGTGAAACAG AAGATGAAAG AGTAGGTGAA GATACGCCTT TCCTGGGCAT ACAGAACCCC
    CTGGCAGCCA GTCTTGAGGC AACACCTGCC TTCCGCCTGG CTGACAGCAG GACTAACCCA
    GCAGGCCGCT TCTCGACACA GGAAGAAATC CAGGCCAGGC TGTCTAGTGT AATTGCTAAC
    CAAGACCCTA TTGCTGTATA A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_016868859.1
    CDS1577..3037
    Translation

    Target ORF information:

    RefSeq Version XM_017013370.1
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant X10, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_017013370.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    ATGCAGATTC CTAAACACAT AAGCATTGAA GATATTACAG CTACATCTAC ATCCACCACT 
    GGGACAAGCC ATCTTGTAAA ATGTGCGGAG AAGGAGAAAA CTTTCTGTGT GAATGGAGGG
    GAGTGCTTCA TGGTGAAAGA CCTTTCAAAC CCCTCGAGAT ACTTGTGCAA GTGCCAACCT
    GGATTCACTG GAGCAAGATG TACTGAGAAT GTGCCCATGA AAGTCCAAAA CCAAGAAAAG
    GCGGAGGAGC TGTACCAGAA GAGAGTGCTG ACCATAACCG GCATCTGCAT CGCCCTCCTT
    GTGGTCGGCA TCATGTGTGT GGTGGCCTAC TGCAAAACCA AGAAACAGCG GAAAAAGCTG
    CATGACCGTC TTCGGCAGAG CCTTCGGTCT GAACGAAACA ATATGATGAA CATTGCCAAT
    GGGCCTCACC ATCCTAACCC ACCCCCCGAG AATGTCCAGC TGGTGAATCA ATACGTATCT
    AAAAACGTCA TCTCCAGTGA GCATATTGTT GAGAGAGAAG CAGAGACATC CTTTTCCACC
    AGTCACTATA CTTCCACAGC CCATCACTCC ACTACTGTCA CCCAGACTCC TAGCCACAGC
    TGGAGCAACG GACACACTGA AAGCATCCTT TCCGAAAGCC ACTCTGTAAT CGTGATGTCA
    TCCGTAGAAA ACAGTAGGCA CAGCAGCCCA ACTGGGGGCC CAAGAGGACG TCTTAATGGC
    ACAGGAGGCC CTCGTGAATG TAACAGCTTC CTCAGGCATG CCAGAGAAAC CCCTGATTCC
    TACCGAGACT CTCCTCATAG TGAAAGGTAT GTGTCAGCCA TGACCACCCC GGCTCGTATG
    TCACCTGTAG ATTTCCACAC GCCAAGCTCC CCCAAATCGC CCCCTTCGGA AATGTCTCCA
    CCCGTGTCCA GCATGACGGT GTCCATGCCT TCCATGGCGG TCAGCCCCTT CATGGAAGAA
    GAGAGACCTC TACTTCTCGT GACACCACCA AGGCTGCGGG AGAAGAAGTT TGACCATCAC
    CCTCAGCAGT TCAGCTCCTT CCACCACAAC CCCGCGCATG ACAGTAACAG CCTCCCTGCT
    AGCCCCTTGA GGATAGTGGA GGATGAGGAG TATGAAACGA CCCAAGAGTA CGAGCCAGCC
    CAAGAGCCTG TTAAGAAACT CGCCAATAGC CGGCGGGCCA AAAGAACCAA GCCCAATGGC
    CACATTGCTA ACAGATTGGA AGTGGACAGC AACACAAGCT CCCAGAGCAG TAACTCAGAG
    AGTGAAACAG AAGATGAAAG AGTAGGTGAA GATACGCCTT TCCTGGGCAT ACAGAACCCC
    CTGGCAGCCA GTCTTGAGGC AACACCTGCC TTCCGCCTGG CTGACAGCAG GACTAACCCA
    GCAGGCCGCT TCTCGACACA GGAAGAAATC CAGGCCAGGC TGTCTAGTGT AATTGCTAAC
    CAAGACCCTA TTGCTGTATA A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu97939
    Clone ID Related Accession (Same CDS sequence) XM_017013371.2 , XM_017013371.1
    Accession Version XM_017013371.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1410bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-05
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform X11
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017013371.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    ATGGAGCCCG ACGCCAACAG CACCAGCCGC GCGCCGGCCG CCTTCCGAGC CTCTTTCCCC 
    CCTCTGGAGA CGGGCCGGAA CCTCAAGAAG GAGGTCAGCC GGGTGCTGTG CAAGCGGTGC
    GCCTTGCCTC CCCGATTGAA AGAGATGAAA AGCCAGGAAT CGGCTGCAGG TTCCAAACTA
    GTCCTTCGGT GTGAAACCAG TTCTGAATAC TCCTCTCTCA GATTCAAGTG GTTCAAGAAT
    GGGAATGAAT TGAATCGAAA AAACAAACCA CAAAATATCA AGATACAAAA AAAGCCAGGG
    AAGTCAGAAC TTCGCATTAA CAAAGCATCA CTGGCTGATT CTGGAGAGTA TATGTGCAAA
    GTGATCAGCA AATTAGGAAA TGACAGTGCC TCTGCCAATA TCACCATCGT GGAATCAAAC
    GAGATCATCA CTGGTATGCC AGCCTCAACT GAAGGAGCAT ATGTGTCTTC AGAGTCTCCC
    ATTAGAATAT CAGTATCCAC AGAAGGAGCA AATACTTCTT CATCTACATC TACATCCACC
    ACTGGGACAA GCCATCTTGT AAAATGTGCG GAGAAGGAGA AAACTTTCTG TGTGAATGGA
    GGGGAGTGCT TCATGGTGAA AGACCTTTCA AACCCCTCGA GATACTTGTG CAAGTGCCAA
    CCTGGATTCA CTGGAGCAAG ATGTACTGAG AATGTGCCCA TGAAAGTCCA AAACCAAGAA
    AAGGCGGAGG AGCTGTACCA GAAGAGAGTG CTGACCATAA CCGGCATCTG CATCGCCCTC
    CTTGTGGTCG GCATCATGTG TGTGGTGGCC TACTGCAAAA CCAAGAAACA GCGGAAAAAG
    CTGCATGACC GTCTTCGGCA GAGCCTTCGG TCTGAACGAA ACAATATGAT GAACATTGCC
    AATGGGCCTC ACCATCCTAA CCCACCCCCC GAGAATGTCC AGCTGGTGAA TCAATACGTA
    TCTAAAAACG TCATCTCCAG TGAGCATATT GTTGAGAGAG AAGCAGAGAC ATCCTTTTCC
    ACCAGTCACT ATACTTCCAC AGCCCATCAC TCCACTACTG TCACCCAGAC TCCTAGCCAC
    AGCTGGAGCA ACGGACACAC TGAAAGCATC CTTTCCGAAA GCCACTCTGT AATCGTGATG
    TCATCCGTAG AAAACAGTAG GCACAGCAGC CCAACTGGGG GCCCAAGAGG ACGTCTTAAT
    GGCACAGGAG GCCCTCGTGA ATGTAACAGC TTCCTCAGGC ATGCCAGAGA AACCCCTGAT
    TCCTACCGAG ACTCTCCTCA TAGTGAAAGA CATAACCTTA TAGCTGAGCT AAGGAGAAAC
    AAGGCACACA GATCCAAATG CATGCAGATC CAGCTATCAG CAACTCATCT TAGATCTTCT
    TCCATTCCCC ATTTGGGCTT CATTCTCTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_016868860.1
    CDS245..1654
    Translation

    Target ORF information:

    RefSeq Version XM_017013371.2
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant X11, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_017013371.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    ATGGAGCCCG ACGCCAACAG CACCAGCCGC GCGCCGGCCG CCTTCCGAGC CTCTTTCCCC 
    CCTCTGGAGA CGGGCCGGAA CCTCAAGAAG GAGGTCAGCC GGGTGCTGTG CAAGCGGTGC
    GCCTTGCCTC CCCGATTGAA AGAGATGAAA AGCCAGGAAT CGGCTGCAGG TTCCAAACTA
    GTCCTTCGGT GTGAAACCAG TTCTGAATAC TCCTCTCTCA GATTCAAGTG GTTCAAGAAT
    GGGAATGAAT TGAATCGAAA AAACAAACCA CAAAATATCA AGATACAAAA AAAGCCAGGG
    AAGTCAGAAC TTCGCATTAA CAAAGCATCA CTGGCTGATT CTGGAGAGTA TATGTGCAAA
    GTGATCAGCA AATTAGGAAA TGACAGTGCC TCTGCCAATA TCACCATCGT GGAATCAAAC
    GAGATCATCA CTGGTATGCC AGCCTCAACT GAAGGAGCAT ATGTGTCTTC AGAGTCTCCC
    ATTAGAATAT CAGTATCCAC AGAAGGAGCA AATACTTCTT CATCTACATC TACATCCACC
    ACTGGGACAA GCCATCTTGT AAAATGTGCG GAGAAGGAGA AAACTTTCTG TGTGAATGGA
    GGGGAGTGCT TCATGGTGAA AGACCTTTCA AACCCCTCGA GATACTTGTG CAAGTGCCAA
    CCTGGATTCA CTGGAGCAAG ATGTACTGAG AATGTGCCCA TGAAAGTCCA AAACCAAGAA
    AAGGCGGAGG AGCTGTACCA GAAGAGAGTG CTGACCATAA CCGGCATCTG CATCGCCCTC
    CTTGTGGTCG GCATCATGTG TGTGGTGGCC TACTGCAAAA CCAAGAAACA GCGGAAAAAG
    CTGCATGACC GTCTTCGGCA GAGCCTTCGG TCTGAACGAA ACAATATGAT GAACATTGCC
    AATGGGCCTC ACCATCCTAA CCCACCCCCC GAGAATGTCC AGCTGGTGAA TCAATACGTA
    TCTAAAAACG TCATCTCCAG TGAGCATATT GTTGAGAGAG AAGCAGAGAC ATCCTTTTCC
    ACCAGTCACT ATACTTCCAC AGCCCATCAC TCCACTACTG TCACCCAGAC TCCTAGCCAC
    AGCTGGAGCA ACGGACACAC TGAAAGCATC CTTTCCGAAA GCCACTCTGT AATCGTGATG
    TCATCCGTAG AAAACAGTAG GCACAGCAGC CCAACTGGGG GCCCAAGAGG ACGTCTTAAT
    GGCACAGGAG GCCCTCGTGA ATGTAACAGC TTCCTCAGGC ATGCCAGAGA AACCCCTGAT
    TCCTACCGAG ACTCTCCTCA TAGTGAAAGA CATAACCTTA TAGCTGAGCT AAGGAGAAAC
    AAGGCACACA GATCCAAATG CATGCAGATC CAGCTATCAG CAACTCATCT TAGATCTTCT
    TCCATTCCCC ATTTGGGCTT CATTCTCTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu97939
    Clone ID Related Accession (Same CDS sequence) XM_017013371.2 , XM_017013371.1
    Accession Version XM_017013371.1 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1410bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2016-06-05
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform X10
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    ATGGAGCCCG ACGCCAACAG CACCAGCCGC GCGCCGGCCG CCTTCCGAGC CTCTTTCCCC 
    CCTCTGGAGA CGGGCCGGAA CCTCAAGAAG GAGGTCAGCC GGGTGCTGTG CAAGCGGTGC
    GCCTTGCCTC CCCGATTGAA AGAGATGAAA AGCCAGGAAT CGGCTGCAGG TTCCAAACTA
    GTCCTTCGGT GTGAAACCAG TTCTGAATAC TCCTCTCTCA GATTCAAGTG GTTCAAGAAT
    GGGAATGAAT TGAATCGAAA AAACAAACCA CAAAATATCA AGATACAAAA AAAGCCAGGG
    AAGTCAGAAC TTCGCATTAA CAAAGCATCA CTGGCTGATT CTGGAGAGTA TATGTGCAAA
    GTGATCAGCA AATTAGGAAA TGACAGTGCC TCTGCCAATA TCACCATCGT GGAATCAAAC
    GAGATCATCA CTGGTATGCC AGCCTCAACT GAAGGAGCAT ATGTGTCTTC AGAGTCTCCC
    ATTAGAATAT CAGTATCCAC AGAAGGAGCA AATACTTCTT CATCTACATC TACATCCACC
    ACTGGGACAA GCCATCTTGT AAAATGTGCG GAGAAGGAGA AAACTTTCTG TGTGAATGGA
    GGGGAGTGCT TCATGGTGAA AGACCTTTCA AACCCCTCGA GATACTTGTG CAAGTGCCAA
    CCTGGATTCA CTGGAGCAAG ATGTACTGAG AATGTGCCCA TGAAAGTCCA AAACCAAGAA
    AAGGCGGAGG AGCTGTACCA GAAGAGAGTG CTGACCATAA CCGGCATCTG CATCGCCCTC
    CTTGTGGTCG GCATCATGTG TGTGGTGGCC TACTGCAAAA CCAAGAAACA GCGGAAAAAG
    CTGCATGACC GTCTTCGGCA GAGCCTTCGG TCTGAACGAA ACAATATGAT GAACATTGCC
    AATGGGCCTC ACCATCCTAA CCCACCCCCC GAGAATGTCC AGCTGGTGAA TCAATACGTA
    TCTAAAAACG TCATCTCCAG TGAGCATATT GTTGAGAGAG AAGCAGAGAC ATCCTTTTCC
    ACCAGTCACT ATACTTCCAC AGCCCATCAC TCCACTACTG TCACCCAGAC TCCTAGCCAC
    AGCTGGAGCA ACGGACACAC TGAAAGCATC CTTTCCGAAA GCCACTCTGT AATCGTGATG
    TCATCCGTAG AAAACAGTAG GCACAGCAGC CCAACTGGGG GCCCAAGAGG ACGTCTTAAT
    GGCACAGGAG GCCCTCGTGA ATGTAACAGC TTCCTCAGGC ATGCCAGAGA AACCCCTGAT
    TCCTACCGAG ACTCTCCTCA TAGTGAAAGA CATAACCTTA TAGCTGAGCT AAGGAGAAAC
    AAGGCACACA GATCCAAATG CATGCAGATC CAGCTATCAG CAACTCATCT TAGATCTTCT
    TCCATTCCCC ATTTGGGCTT CATTCTCTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_016868860.1
    CDS209..1618
    Translation

    Target ORF information:

    RefSeq Version XM_017013371.1
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant X10, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_017013371.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    ATGGAGCCCG ACGCCAACAG CACCAGCCGC GCGCCGGCCG CCTTCCGAGC CTCTTTCCCC 
    CCTCTGGAGA CGGGCCGGAA CCTCAAGAAG GAGGTCAGCC GGGTGCTGTG CAAGCGGTGC
    GCCTTGCCTC CCCGATTGAA AGAGATGAAA AGCCAGGAAT CGGCTGCAGG TTCCAAACTA
    GTCCTTCGGT GTGAAACCAG TTCTGAATAC TCCTCTCTCA GATTCAAGTG GTTCAAGAAT
    GGGAATGAAT TGAATCGAAA AAACAAACCA CAAAATATCA AGATACAAAA AAAGCCAGGG
    AAGTCAGAAC TTCGCATTAA CAAAGCATCA CTGGCTGATT CTGGAGAGTA TATGTGCAAA
    GTGATCAGCA AATTAGGAAA TGACAGTGCC TCTGCCAATA TCACCATCGT GGAATCAAAC
    GAGATCATCA CTGGTATGCC AGCCTCAACT GAAGGAGCAT ATGTGTCTTC AGAGTCTCCC
    ATTAGAATAT CAGTATCCAC AGAAGGAGCA AATACTTCTT CATCTACATC TACATCCACC
    ACTGGGACAA GCCATCTTGT AAAATGTGCG GAGAAGGAGA AAACTTTCTG TGTGAATGGA
    GGGGAGTGCT TCATGGTGAA AGACCTTTCA AACCCCTCGA GATACTTGTG CAAGTGCCAA
    CCTGGATTCA CTGGAGCAAG ATGTACTGAG AATGTGCCCA TGAAAGTCCA AAACCAAGAA
    AAGGCGGAGG AGCTGTACCA GAAGAGAGTG CTGACCATAA CCGGCATCTG CATCGCCCTC
    CTTGTGGTCG GCATCATGTG TGTGGTGGCC TACTGCAAAA CCAAGAAACA GCGGAAAAAG
    CTGCATGACC GTCTTCGGCA GAGCCTTCGG TCTGAACGAA ACAATATGAT GAACATTGCC
    AATGGGCCTC ACCATCCTAA CCCACCCCCC GAGAATGTCC AGCTGGTGAA TCAATACGTA
    TCTAAAAACG TCATCTCCAG TGAGCATATT GTTGAGAGAG AAGCAGAGAC ATCCTTTTCC
    ACCAGTCACT ATACTTCCAC AGCCCATCAC TCCACTACTG TCACCCAGAC TCCTAGCCAC
    AGCTGGAGCA ACGGACACAC TGAAAGCATC CTTTCCGAAA GCCACTCTGT AATCGTGATG
    TCATCCGTAG AAAACAGTAG GCACAGCAGC CCAACTGGGG GCCCAAGAGG ACGTCTTAAT
    GGCACAGGAG GCCCTCGTGA ATGTAACAGC TTCCTCAGGC ATGCCAGAGA AACCCCTGAT
    TCCTACCGAG ACTCTCCTCA TAGTGAAAGA CATAACCTTA TAGCTGAGCT AAGGAGAAAC
    AAGGCACACA GATCCAAATG CATGCAGATC CAGCTATCAG CAACTCATCT TAGATCTTCT
    TCCATTCCCC ATTTGGGCTT CATTCTCTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu97940
    Clone ID Related Accession (Same CDS sequence) XM_017013372.2 , XM_017013372.1
    Accession Version XM_017013372.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1401bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-05
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform X12
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017013372.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    ATGGAGCCCG ACGCCAACAG CACCAGCCGC GCGCCGGCCG CCTTCCGAGC CTCTTTCCCC 
    CCTCTGGAGA CGGGCCGGAA CCTCAAGAAG GAGGTCAGCC GGGTGCTGTG CAAGCGGTGC
    GCCTTGCCTC CCCGATTGAA AGAGATGAAA AGCCAGGAAT CGGCTGCAGG TTCCAAACTA
    GTCCTTCGGT GTGAAACCAG TTCTGAATAC TCCTCTCTCA GATTCAAGTG GTTCAAGAAT
    GGGAATGAAT TGAATCGAAA AAACAAACCA CAAAATATCA AGATACAAAA AAAGCCAGGG
    AAGTCAGAAC TTCGCATTAA CAAAGCATCA CTGGCTGATT CTGGAGAGTA TATGTGCAAA
    GTGATCAGCA AATTAGGAAA TGACAGTGCC TCTGCCAATA TCACCATCGT GGAATCAAAC
    GAGATCATCA CTGGTATGCC AGCCTCAACT GAAGGAGCAT ATGTGTCTTC AGAGTCTCCC
    ATTAGAATAT CAGTATCCAC AGAAGGAGCA AATACTTCTT CATCTACATC TACATCCACC
    ACTGGGACAA GCCATCTTGT AAAATGTGCG GAGAAGGAGA AAACTTTCTG TGTGAATGGA
    GGGGAGTGCT TCATGGTGAA AGACCTTTCA AACCCCTCGA GATACTTGTG CAAGTGCCCA
    AATGAGTTTA CTGGTGATCG CTGCCAAAAC TACGTAATGG CCAGCTTCTA CAAGGCGGAG
    GAGCTGTACC AGAAGAGAGT GCTGACCATA ACCGGCATCT GCATCGCCCT CCTTGTGGTC
    GGCATCATGT GTGTGGTGGC CTACTGCAAA ACCAAGAAAC AGCGGAAAAA GCTGCATGAC
    CGTCTTCGGC AGAGCCTTCG GTCTGAACGA AACAATATGA TGAACATTGC CAATGGGCCT
    CACCATCCTA ACCCACCCCC CGAGAATGTC CAGCTGGTGA ATCAATACGT ATCTAAAAAC
    GTCATCTCCA GTGAGCATAT TGTTGAGAGA GAAGCAGAGA CATCCTTTTC CACCAGTCAC
    TATACTTCCA CAGCCCATCA CTCCACTACT GTCACCCAGA CTCCTAGCCA CAGCTGGAGC
    AACGGACACA CTGAAAGCAT CCTTTCCGAA AGCCACTCTG TAATCGTGAT GTCATCCGTA
    GAAAACAGTA GGCACAGCAG CCCAACTGGG GGCCCAAGAG GACGTCTTAA TGGCACAGGA
    GGCCCTCGTG AATGTAACAG CTTCCTCAGG CATGCCAGAG AAACCCCTGA TTCCTACCGA
    GACTCTCCTC ATAGTGAAAG ACATAACCTT ATAGCTGAGC TAAGGAGAAA CAAGGCACAC
    AGATCCAAAT GCATGCAGAT CCAGCTATCA GCAACTCATC TTAGATCTTC TTCCATTCCC
    CATTTGGGCT TCATTCTCTA A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_016868861.1
    CDS245..1645
    Translation

    Target ORF information:

    RefSeq Version XM_017013372.2
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant X12, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_017013372.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    ATGGAGCCCG ACGCCAACAG CACCAGCCGC GCGCCGGCCG CCTTCCGAGC CTCTTTCCCC 
    CCTCTGGAGA CGGGCCGGAA CCTCAAGAAG GAGGTCAGCC GGGTGCTGTG CAAGCGGTGC
    GCCTTGCCTC CCCGATTGAA AGAGATGAAA AGCCAGGAAT CGGCTGCAGG TTCCAAACTA
    GTCCTTCGGT GTGAAACCAG TTCTGAATAC TCCTCTCTCA GATTCAAGTG GTTCAAGAAT
    GGGAATGAAT TGAATCGAAA AAACAAACCA CAAAATATCA AGATACAAAA AAAGCCAGGG
    AAGTCAGAAC TTCGCATTAA CAAAGCATCA CTGGCTGATT CTGGAGAGTA TATGTGCAAA
    GTGATCAGCA AATTAGGAAA TGACAGTGCC TCTGCCAATA TCACCATCGT GGAATCAAAC
    GAGATCATCA CTGGTATGCC AGCCTCAACT GAAGGAGCAT ATGTGTCTTC AGAGTCTCCC
    ATTAGAATAT CAGTATCCAC AGAAGGAGCA AATACTTCTT CATCTACATC TACATCCACC
    ACTGGGACAA GCCATCTTGT AAAATGTGCG GAGAAGGAGA AAACTTTCTG TGTGAATGGA
    GGGGAGTGCT TCATGGTGAA AGACCTTTCA AACCCCTCGA GATACTTGTG CAAGTGCCCA
    AATGAGTTTA CTGGTGATCG CTGCCAAAAC TACGTAATGG CCAGCTTCTA CAAGGCGGAG
    GAGCTGTACC AGAAGAGAGT GCTGACCATA ACCGGCATCT GCATCGCCCT CCTTGTGGTC
    GGCATCATGT GTGTGGTGGC CTACTGCAAA ACCAAGAAAC AGCGGAAAAA GCTGCATGAC
    CGTCTTCGGC AGAGCCTTCG GTCTGAACGA AACAATATGA TGAACATTGC CAATGGGCCT
    CACCATCCTA ACCCACCCCC CGAGAATGTC CAGCTGGTGA ATCAATACGT ATCTAAAAAC
    GTCATCTCCA GTGAGCATAT TGTTGAGAGA GAAGCAGAGA CATCCTTTTC CACCAGTCAC
    TATACTTCCA CAGCCCATCA CTCCACTACT GTCACCCAGA CTCCTAGCCA CAGCTGGAGC
    AACGGACACA CTGAAAGCAT CCTTTCCGAA AGCCACTCTG TAATCGTGAT GTCATCCGTA
    GAAAACAGTA GGCACAGCAG CCCAACTGGG GGCCCAAGAG GACGTCTTAA TGGCACAGGA
    GGCCCTCGTG AATGTAACAG CTTCCTCAGG CATGCCAGAG AAACCCCTGA TTCCTACCGA
    GACTCTCCTC ATAGTGAAAG ACATAACCTT ATAGCTGAGC TAAGGAGAAA CAAGGCACAC
    AGATCCAAAT GCATGCAGAT CCAGCTATCA GCAACTCATC TTAGATCTTC TTCCATTCCC
    CATTTGGGCT TCATTCTCTA A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu97940
    Clone ID Related Accession (Same CDS sequence) XM_017013372.2 , XM_017013372.1
    Accession Version XM_017013372.1 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1401bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2016-06-05
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform X11
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    ATGGAGCCCG ACGCCAACAG CACCAGCCGC GCGCCGGCCG CCTTCCGAGC CTCTTTCCCC 
    CCTCTGGAGA CGGGCCGGAA CCTCAAGAAG GAGGTCAGCC GGGTGCTGTG CAAGCGGTGC
    GCCTTGCCTC CCCGATTGAA AGAGATGAAA AGCCAGGAAT CGGCTGCAGG TTCCAAACTA
    GTCCTTCGGT GTGAAACCAG TTCTGAATAC TCCTCTCTCA GATTCAAGTG GTTCAAGAAT
    GGGAATGAAT TGAATCGAAA AAACAAACCA CAAAATATCA AGATACAAAA AAAGCCAGGG
    AAGTCAGAAC TTCGCATTAA CAAAGCATCA CTGGCTGATT CTGGAGAGTA TATGTGCAAA
    GTGATCAGCA AATTAGGAAA TGACAGTGCC TCTGCCAATA TCACCATCGT GGAATCAAAC
    GAGATCATCA CTGGTATGCC AGCCTCAACT GAAGGAGCAT ATGTGTCTTC AGAGTCTCCC
    ATTAGAATAT CAGTATCCAC AGAAGGAGCA AATACTTCTT CATCTACATC TACATCCACC
    ACTGGGACAA GCCATCTTGT AAAATGTGCG GAGAAGGAGA AAACTTTCTG TGTGAATGGA
    GGGGAGTGCT TCATGGTGAA AGACCTTTCA AACCCCTCGA GATACTTGTG CAAGTGCCCA
    AATGAGTTTA CTGGTGATCG CTGCCAAAAC TACGTAATGG CCAGCTTCTA CAAGGCGGAG
    GAGCTGTACC AGAAGAGAGT GCTGACCATA ACCGGCATCT GCATCGCCCT CCTTGTGGTC
    GGCATCATGT GTGTGGTGGC CTACTGCAAA ACCAAGAAAC AGCGGAAAAA GCTGCATGAC
    CGTCTTCGGC AGAGCCTTCG GTCTGAACGA AACAATATGA TGAACATTGC CAATGGGCCT
    CACCATCCTA ACCCACCCCC CGAGAATGTC CAGCTGGTGA ATCAATACGT ATCTAAAAAC
    GTCATCTCCA GTGAGCATAT TGTTGAGAGA GAAGCAGAGA CATCCTTTTC CACCAGTCAC
    TATACTTCCA CAGCCCATCA CTCCACTACT GTCACCCAGA CTCCTAGCCA CAGCTGGAGC
    AACGGACACA CTGAAAGCAT CCTTTCCGAA AGCCACTCTG TAATCGTGAT GTCATCCGTA
    GAAAACAGTA GGCACAGCAG CCCAACTGGG GGCCCAAGAG GACGTCTTAA TGGCACAGGA
    GGCCCTCGTG AATGTAACAG CTTCCTCAGG CATGCCAGAG AAACCCCTGA TTCCTACCGA
    GACTCTCCTC ATAGTGAAAG ACATAACCTT ATAGCTGAGC TAAGGAGAAA CAAGGCACAC
    AGATCCAAAT GCATGCAGAT CCAGCTATCA GCAACTCATC TTAGATCTTC TTCCATTCCC
    CATTTGGGCT TCATTCTCTA A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_016868861.1
    CDS209..1609
    Translation

    Target ORF information:

    RefSeq Version XM_017013372.1
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant X11, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_017013372.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    ATGGAGCCCG ACGCCAACAG CACCAGCCGC GCGCCGGCCG CCTTCCGAGC CTCTTTCCCC 
    CCTCTGGAGA CGGGCCGGAA CCTCAAGAAG GAGGTCAGCC GGGTGCTGTG CAAGCGGTGC
    GCCTTGCCTC CCCGATTGAA AGAGATGAAA AGCCAGGAAT CGGCTGCAGG TTCCAAACTA
    GTCCTTCGGT GTGAAACCAG TTCTGAATAC TCCTCTCTCA GATTCAAGTG GTTCAAGAAT
    GGGAATGAAT TGAATCGAAA AAACAAACCA CAAAATATCA AGATACAAAA AAAGCCAGGG
    AAGTCAGAAC TTCGCATTAA CAAAGCATCA CTGGCTGATT CTGGAGAGTA TATGTGCAAA
    GTGATCAGCA AATTAGGAAA TGACAGTGCC TCTGCCAATA TCACCATCGT GGAATCAAAC
    GAGATCATCA CTGGTATGCC AGCCTCAACT GAAGGAGCAT ATGTGTCTTC AGAGTCTCCC
    ATTAGAATAT CAGTATCCAC AGAAGGAGCA AATACTTCTT CATCTACATC TACATCCACC
    ACTGGGACAA GCCATCTTGT AAAATGTGCG GAGAAGGAGA AAACTTTCTG TGTGAATGGA
    GGGGAGTGCT TCATGGTGAA AGACCTTTCA AACCCCTCGA GATACTTGTG CAAGTGCCCA
    AATGAGTTTA CTGGTGATCG CTGCCAAAAC TACGTAATGG CCAGCTTCTA CAAGGCGGAG
    GAGCTGTACC AGAAGAGAGT GCTGACCATA ACCGGCATCT GCATCGCCCT CCTTGTGGTC
    GGCATCATGT GTGTGGTGGC CTACTGCAAA ACCAAGAAAC AGCGGAAAAA GCTGCATGAC
    CGTCTTCGGC AGAGCCTTCG GTCTGAACGA AACAATATGA TGAACATTGC CAATGGGCCT
    CACCATCCTA ACCCACCCCC CGAGAATGTC CAGCTGGTGA ATCAATACGT ATCTAAAAAC
    GTCATCTCCA GTGAGCATAT TGTTGAGAGA GAAGCAGAGA CATCCTTTTC CACCAGTCAC
    TATACTTCCA CAGCCCATCA CTCCACTACT GTCACCCAGA CTCCTAGCCA CAGCTGGAGC
    AACGGACACA CTGAAAGCAT CCTTTCCGAA AGCCACTCTG TAATCGTGAT GTCATCCGTA
    GAAAACAGTA GGCACAGCAG CCCAACTGGG GGCCCAAGAG GACGTCTTAA TGGCACAGGA
    GGCCCTCGTG AATGTAACAG CTTCCTCAGG CATGCCAGAG AAACCCCTGA TTCCTACCGA
    GACTCTCCTC ATAGTGAAAG ACATAACCTT ATAGCTGAGC TAAGGAGAAA CAAGGCACAC
    AGATCCAAAT GCATGCAGAT CCAGCTATCA GCAACTCATC TTAGATCTTC TTCCATTCCC
    CATTTGGGCT TCATTCTCTA A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu42054
    Clone ID Related Accession (Same CDS sequence) XM_005273486.3
    Accession Version XM_005273486.3 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 2088bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-05
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform X1
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005273486.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    ATGGAGATTT ATTCCCCAGA CATGTCTGAG GTCGCCGCCG AGAGGTCCTC CAGCCCCTCC 
    ACTCAGCTGA GTGCAGACCC ATCTCTTGAT GGGCTTCCGG CAGCAGAAGA CATGCCAGAG
    CCCCAGACTG AAGATGGGAG AACCCCTGGA CTCGTGGGCC TGGCCGTGCC CTGCTGTGCG
    TGCCTAGAAG CTGAGCGCCT GAGAGGTTGC CTCAACTCAG AGAAAATCTG CATTGTCCCC
    ATCCTGGCTT GCCTGGTCAG CCTCTGCCTC TGCATCGCCG GCCTCAAGTG GGTATTTGTG
    GACAAGATCT TTGAATATGA CTCTCCTACT CACCTTGACC CTGGGGGGTT AGGCCAGGAC
    CCTATTATTT CTCTGGACGC AACTGCTGCC TCAGCTGTGT GGGTGTCGTC TGAGGCATAC
    ACTTCACCTG TCTCTAGGGC TCAATCTGAA AGTGAGGTTC AAGTTACAGT GCAAGGTGAC
    AAGGCTGTTG TCTCCTTTGA ACCATCAGCG GCACCGACAC CGAAGAATCG TATTTTTGCC
    TTTTCTTTCT TGCCGTCCAC TGCGCCATCC TTCCCTTCAC CCACCCGGAA CCCTGAGGTG
    AGAACGCCCA AGTCAGCAAC TCAGCCACAA ACAACAGAAA CTAATCTCCA AACTGCTCCT
    AAACTTTCTA CATCTACATC CACCACTGGG ACAAGCCATC TTGTAAAATG TGCGGAGAAG
    GAGAAAACTT TCTGTGTGAA TGGAGGGGAG TGCTTCATGG TGAAAGACCT TTCAAACCCC
    TCGAGATACT TGTGCAAGTG CCAACCTGGA TTCACTGGAG CAAGATGTAC TGAGAATGTG
    CCCATGAAAG TCCAAAACCA AGAAAAGGCG GAGGAGCTGT ACCAGAAGAG AGTGCTGACC
    ATAACCGGCA TCTGCATCGC CCTCCTTGTG GTCGGCATCA TGTGTGTGGT GGCCTACTGC
    AAAACCAAGA AACAGCGGAA AAAGCTGCAT GACCGTCTTC GGCAGAGCCT TCGGTCTGAA
    CGAAACAATA TGATGAACAT TGCCAATGGG CCTCACCATC CTAACCCACC CCCCGAGAAT
    GTCCAGCTGG TGAATCAATA CGTATCTAAA AACGTCATCT CCAGTGAGCA TATTGTTGAG
    AGAGAAGCAG AGACATCCTT TTCCACCAGT CACTATACTT CCACAGCCCA TCACTCCACT
    ACTGTCACCC AGACTCCTAG CCACAGCTGG AGCAACGGAC ACACTGAAAG CATCCTTTCC
    GAAAGCCACT CTGTAATCGT GATGTCATCC GTAGAAAACA GTAGGCACAG CAGCCCAACT
    GGGGGCCCAA GAGGACGTCT TAATGGCACA GGAGGCCCTC GTGAATGTAA CAGCTTCCTC
    AGGCATGCCA GAGAAACCCC TGATTCCTAC CGAGACTCTC CTCATAGTGA AAGGTATGTG
    TCAGCCATGA CCACCCCGGC TCGTATGTCA CCTGTAGATT TCCACACGCC AAGCTCCCCC
    AAATCGCCCC CTTCGGAAAT GTCTCCACCC GTGTCCAGCA TGACGGTGTC CATGCCTTCC
    ATGGCGGTCA GCCCCTTCAT GGAAGAAGAG AGACCTCTAC TTCTCGTGAC ACCACCAAGG
    CTGCGGGAGA AGAAGTTTGA CCATCACCCT CAGCAGTTCA GCTCCTTCCA CCACAACCCC
    GCGCATGACA GTAACAGCCT CCCTGCTAGC CCCTTGAGGA TAGTGGAGGA TGAGGAGTAT
    GAAACGACCC AAGAGTACGA GCCAGCCCAA GAGCCTGTTA AGAAACTCGC CAATAGCCGG
    CGGGCCAAAA GAACCAAGCC CAATGGCCAC ATTGCTAACA GATTGGAAGT GGACAGCAAC
    ACAAGCTCCC AGAGCAGTAA CTCAGAGAGT GAAACAGAAG ATGAAAGAGT AGGTGAAGAT
    ACGCCTTTCC TGGGCATACA GAACCCCCTG GCAGCCAGTC TTGAGGCAAC ACCTGCCTTC
    CGCCTGGCTG ACAGCAGGAC TAACCCAGCA GGCCGCTTCT CGACACAGGA AGAAATCCAG
    GCCAGGCTGT CTAGTGTAAT TGCTAACCAA GACCCTATTG CTGTATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_005273543.1
    CDS987..3074
    Translation

    Target ORF information:

    RefSeq Version XM_005273486.3
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant X1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_005273486.3

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    ATGGAGATTT ATTCCCCAGA CATGTCTGAG GTCGCCGCCG AGAGGTCCTC CAGCCCCTCC 
    ACTCAGCTGA GTGCAGACCC ATCTCTTGAT GGGCTTCCGG CAGCAGAAGA CATGCCAGAG
    CCCCAGACTG AAGATGGGAG AACCCCTGGA CTCGTGGGCC TGGCCGTGCC CTGCTGTGCG
    TGCCTAGAAG CTGAGCGCCT GAGAGGTTGC CTCAACTCAG AGAAAATCTG CATTGTCCCC
    ATCCTGGCTT GCCTGGTCAG CCTCTGCCTC TGCATCGCCG GCCTCAAGTG GGTATTTGTG
    GACAAGATCT TTGAATATGA CTCTCCTACT CACCTTGACC CTGGGGGGTT AGGCCAGGAC
    CCTATTATTT CTCTGGACGC AACTGCTGCC TCAGCTGTGT GGGTGTCGTC TGAGGCATAC
    ACTTCACCTG TCTCTAGGGC TCAATCTGAA AGTGAGGTTC AAGTTACAGT GCAAGGTGAC
    AAGGCTGTTG TCTCCTTTGA ACCATCAGCG GCACCGACAC CGAAGAATCG TATTTTTGCC
    TTTTCTTTCT TGCCGTCCAC TGCGCCATCC TTCCCTTCAC CCACCCGGAA CCCTGAGGTG
    AGAACGCCCA AGTCAGCAAC TCAGCCACAA ACAACAGAAA CTAATCTCCA AACTGCTCCT
    AAACTTTCTA CATCTACATC CACCACTGGG ACAAGCCATC TTGTAAAATG TGCGGAGAAG
    GAGAAAACTT TCTGTGTGAA TGGAGGGGAG TGCTTCATGG TGAAAGACCT TTCAAACCCC
    TCGAGATACT TGTGCAAGTG CCAACCTGGA TTCACTGGAG CAAGATGTAC TGAGAATGTG
    CCCATGAAAG TCCAAAACCA AGAAAAGGCG GAGGAGCTGT ACCAGAAGAG AGTGCTGACC
    ATAACCGGCA TCTGCATCGC CCTCCTTGTG GTCGGCATCA TGTGTGTGGT GGCCTACTGC
    AAAACCAAGA AACAGCGGAA AAAGCTGCAT GACCGTCTTC GGCAGAGCCT TCGGTCTGAA
    CGAAACAATA TGATGAACAT TGCCAATGGG CCTCACCATC CTAACCCACC CCCCGAGAAT
    GTCCAGCTGG TGAATCAATA CGTATCTAAA AACGTCATCT CCAGTGAGCA TATTGTTGAG
    AGAGAAGCAG AGACATCCTT TTCCACCAGT CACTATACTT CCACAGCCCA TCACTCCACT
    ACTGTCACCC AGACTCCTAG CCACAGCTGG AGCAACGGAC ACACTGAAAG CATCCTTTCC
    GAAAGCCACT CTGTAATCGT GATGTCATCC GTAGAAAACA GTAGGCACAG CAGCCCAACT
    GGGGGCCCAA GAGGACGTCT TAATGGCACA GGAGGCCCTC GTGAATGTAA CAGCTTCCTC
    AGGCATGCCA GAGAAACCCC TGATTCCTAC CGAGACTCTC CTCATAGTGA AAGGTATGTG
    TCAGCCATGA CCACCCCGGC TCGTATGTCA CCTGTAGATT TCCACACGCC AAGCTCCCCC
    AAATCGCCCC CTTCGGAAAT GTCTCCACCC GTGTCCAGCA TGACGGTGTC CATGCCTTCC
    ATGGCGGTCA GCCCCTTCAT GGAAGAAGAG AGACCTCTAC TTCTCGTGAC ACCACCAAGG
    CTGCGGGAGA AGAAGTTTGA CCATCACCCT CAGCAGTTCA GCTCCTTCCA CCACAACCCC
    GCGCATGACA GTAACAGCCT CCCTGCTAGC CCCTTGAGGA TAGTGGAGGA TGAGGAGTAT
    GAAACGACCC AAGAGTACGA GCCAGCCCAA GAGCCTGTTA AGAAACTCGC CAATAGCCGG
    CGGGCCAAAA GAACCAAGCC CAATGGCCAC ATTGCTAACA GATTGGAAGT GGACAGCAAC
    ACAAGCTCCC AGAGCAGTAA CTCAGAGAGT GAAACAGAAG ATGAAAGAGT AGGTGAAGAT
    ACGCCTTTCC TGGGCATACA GAACCCCCTG GCAGCCAGTC TTGAGGCAAC ACCTGCCTTC
    CGCCTGGCTG ACAGCAGGAC TAACCCAGCA GGCCGCTTCT CGACACAGGA AGAAATCCAG
    GCCAGGCTGT CTAGTGTAAT TGCTAACCAA GACCCTATTG CTGTATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu42055
    Clone ID Related Accession (Same CDS sequence) XM_005273487.3
    Accession Version XM_005273487.3 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 2079bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-05
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform X2
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005273487.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    ATGGAGATTT ATTCCCCAGA CATGTCTGAG GTCGCCGCCG AGAGGTCCTC CAGCCCCTCC 
    ACTCAGCTGA GTGCAGACCC ATCTCTTGAT GGGCTTCCGG CAGCAGAAGA CATGCCAGAG
    CCCCAGACTG AAGATGGGAG AACCCCTGGA CTCGTGGGCC TGGCCGTGCC CTGCTGTGCG
    TGCCTAGAAG CTGAGCGCCT GAGAGGTTGC CTCAACTCAG AGAAAATCTG CATTGTCCCC
    ATCCTGGCTT GCCTGGTCAG CCTCTGCCTC TGCATCGCCG GCCTCAAGTG GGTATTTGTG
    GACAAGATCT TTGAATATGA CTCTCCTACT CACCTTGACC CTGGGGGGTT AGGCCAGGAC
    CCTATTATTT CTCTGGACGC AACTGCTGCC TCAGCTGTGT GGGTGTCGTC TGAGGCATAC
    ACTTCACCTG TCTCTAGGGC TCAATCTGAA AGTGAGGTTC AAGTTACAGT GCAAGGTGAC
    AAGGCTGTTG TCTCCTTTGA ACCATCAGCG GCACCGACAC CGAAGAATCG TATTTTTGCC
    TTTTCTTTCT TGCCGTCCAC TGCGCCATCC TTCCCTTCAC CCACCCGGAA CCCTGAGGTG
    AGAACGCCCA AGTCAGCAAC TCAGCCACAA ACAACAGAAA CTAATCTCCA AACTGCTCCT
    AAACTTTCTA CATCTACATC CACCACTGGG ACAAGCCATC TTGTAAAATG TGCGGAGAAG
    GAGAAAACTT TCTGTGTGAA TGGAGGGGAG TGCTTCATGG TGAAAGACCT TTCAAACCCC
    TCGAGATACT TGTGCAAGTG CCCAAATGAG TTTACTGGTG ATCGCTGCCA AAACTACGTA
    ATGGCCAGCT TCTACAAGGC GGAGGAGCTG TACCAGAAGA GAGTGCTGAC CATAACCGGC
    ATCTGCATCG CCCTCCTTGT GGTCGGCATC ATGTGTGTGG TGGCCTACTG CAAAACCAAG
    AAACAGCGGA AAAAGCTGCA TGACCGTCTT CGGCAGAGCC TTCGGTCTGA ACGAAACAAT
    ATGATGAACA TTGCCAATGG GCCTCACCAT CCTAACCCAC CCCCCGAGAA TGTCCAGCTG
    GTGAATCAAT ACGTATCTAA AAACGTCATC TCCAGTGAGC ATATTGTTGA GAGAGAAGCA
    GAGACATCCT TTTCCACCAG TCACTATACT TCCACAGCCC ATCACTCCAC TACTGTCACC
    CAGACTCCTA GCCACAGCTG GAGCAACGGA CACACTGAAA GCATCCTTTC CGAAAGCCAC
    TCTGTAATCG TGATGTCATC CGTAGAAAAC AGTAGGCACA GCAGCCCAAC TGGGGGCCCA
    AGAGGACGTC TTAATGGCAC AGGAGGCCCT CGTGAATGTA ACAGCTTCCT CAGGCATGCC
    AGAGAAACCC CTGATTCCTA CCGAGACTCT CCTCATAGTG AAAGGTATGT GTCAGCCATG
    ACCACCCCGG CTCGTATGTC ACCTGTAGAT TTCCACACGC CAAGCTCCCC CAAATCGCCC
    CCTTCGGAAA TGTCTCCACC CGTGTCCAGC ATGACGGTGT CCATGCCTTC CATGGCGGTC
    AGCCCCTTCA TGGAAGAAGA GAGACCTCTA CTTCTCGTGA CACCACCAAG GCTGCGGGAG
    AAGAAGTTTG ACCATCACCC TCAGCAGTTC AGCTCCTTCC ACCACAACCC CGCGCATGAC
    AGTAACAGCC TCCCTGCTAG CCCCTTGAGG ATAGTGGAGG ATGAGGAGTA TGAAACGACC
    CAAGAGTACG AGCCAGCCCA AGAGCCTGTT AAGAAACTCG CCAATAGCCG GCGGGCCAAA
    AGAACCAAGC CCAATGGCCA CATTGCTAAC AGATTGGAAG TGGACAGCAA CACAAGCTCC
    CAGAGCAGTA ACTCAGAGAG TGAAACAGAA GATGAAAGAG TAGGTGAAGA TACGCCTTTC
    CTGGGCATAC AGAACCCCCT GGCAGCCAGT CTTGAGGCAA CACCTGCCTT CCGCCTGGCT
    GACAGCAGGA CTAACCCAGC AGGCCGCTTC TCGACACAGG AAGAAATCCA GGCCAGGCTG
    TCTAGTGTAA TTGCTAACCA AGACCCTATT GCTGTATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_005273544.1
    CDS987..3065
    Translation

    Target ORF information:

    RefSeq Version XM_005273487.3
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant X2, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_005273487.3

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    ATGGAGATTT ATTCCCCAGA CATGTCTGAG GTCGCCGCCG AGAGGTCCTC CAGCCCCTCC 
    ACTCAGCTGA GTGCAGACCC ATCTCTTGAT GGGCTTCCGG CAGCAGAAGA CATGCCAGAG
    CCCCAGACTG AAGATGGGAG AACCCCTGGA CTCGTGGGCC TGGCCGTGCC CTGCTGTGCG
    TGCCTAGAAG CTGAGCGCCT GAGAGGTTGC CTCAACTCAG AGAAAATCTG CATTGTCCCC
    ATCCTGGCTT GCCTGGTCAG CCTCTGCCTC TGCATCGCCG GCCTCAAGTG GGTATTTGTG
    GACAAGATCT TTGAATATGA CTCTCCTACT CACCTTGACC CTGGGGGGTT AGGCCAGGAC
    CCTATTATTT CTCTGGACGC AACTGCTGCC TCAGCTGTGT GGGTGTCGTC TGAGGCATAC
    ACTTCACCTG TCTCTAGGGC TCAATCTGAA AGTGAGGTTC AAGTTACAGT GCAAGGTGAC
    AAGGCTGTTG TCTCCTTTGA ACCATCAGCG GCACCGACAC CGAAGAATCG TATTTTTGCC
    TTTTCTTTCT TGCCGTCCAC TGCGCCATCC TTCCCTTCAC CCACCCGGAA CCCTGAGGTG
    AGAACGCCCA AGTCAGCAAC TCAGCCACAA ACAACAGAAA CTAATCTCCA AACTGCTCCT
    AAACTTTCTA CATCTACATC CACCACTGGG ACAAGCCATC TTGTAAAATG TGCGGAGAAG
    GAGAAAACTT TCTGTGTGAA TGGAGGGGAG TGCTTCATGG TGAAAGACCT TTCAAACCCC
    TCGAGATACT TGTGCAAGTG CCCAAATGAG TTTACTGGTG ATCGCTGCCA AAACTACGTA
    ATGGCCAGCT TCTACAAGGC GGAGGAGCTG TACCAGAAGA GAGTGCTGAC CATAACCGGC
    ATCTGCATCG CCCTCCTTGT GGTCGGCATC ATGTGTGTGG TGGCCTACTG CAAAACCAAG
    AAACAGCGGA AAAAGCTGCA TGACCGTCTT CGGCAGAGCC TTCGGTCTGA ACGAAACAAT
    ATGATGAACA TTGCCAATGG GCCTCACCAT CCTAACCCAC CCCCCGAGAA TGTCCAGCTG
    GTGAATCAAT ACGTATCTAA AAACGTCATC TCCAGTGAGC ATATTGTTGA GAGAGAAGCA
    GAGACATCCT TTTCCACCAG TCACTATACT TCCACAGCCC ATCACTCCAC TACTGTCACC
    CAGACTCCTA GCCACAGCTG GAGCAACGGA CACACTGAAA GCATCCTTTC CGAAAGCCAC
    TCTGTAATCG TGATGTCATC CGTAGAAAAC AGTAGGCACA GCAGCCCAAC TGGGGGCCCA
    AGAGGACGTC TTAATGGCAC AGGAGGCCCT CGTGAATGTA ACAGCTTCCT CAGGCATGCC
    AGAGAAACCC CTGATTCCTA CCGAGACTCT CCTCATAGTG AAAGGTATGT GTCAGCCATG
    ACCACCCCGG CTCGTATGTC ACCTGTAGAT TTCCACACGC CAAGCTCCCC CAAATCGCCC
    CCTTCGGAAA TGTCTCCACC CGTGTCCAGC ATGACGGTGT CCATGCCTTC CATGGCGGTC
    AGCCCCTTCA TGGAAGAAGA GAGACCTCTA CTTCTCGTGA CACCACCAAG GCTGCGGGAG
    AAGAAGTTTG ACCATCACCC TCAGCAGTTC AGCTCCTTCC ACCACAACCC CGCGCATGAC
    AGTAACAGCC TCCCTGCTAG CCCCTTGAGG ATAGTGGAGG ATGAGGAGTA TGAAACGACC
    CAAGAGTACG AGCCAGCCCA AGAGCCTGTT AAGAAACTCG CCAATAGCCG GCGGGCCAAA
    AGAACCAAGC CCAATGGCCA CATTGCTAAC AGATTGGAAG TGGACAGCAA CACAAGCTCC
    CAGAGCAGTA ACTCAGAGAG TGAAACAGAA GATGAAAGAG TAGGTGAAGA TACGCCTTTC
    CTGGGCATAC AGAACCCCCT GGCAGCCAGT CTTGAGGCAA CACCTGCCTT CCGCCTGGCT
    GACAGCAGGA CTAACCCAGC AGGCCGCTTC TCGACACAGG AAGAAATCCA GGCCAGGCTG
    TCTAGTGTAA TTGCTAACCA AGACCCTATT GCTGTATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu106016
    Clone ID Related Accession (Same CDS sequence) XM_024447143.1
    Accession Version XM_024447143.1 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1821bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-05
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform X7
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG CTACATCTAC ATCCACCACT
    GGGACAAGCC ATCTTGTAAA ATGTGCGGAG AAGGAGAAAA CTTTCTGTGT GAATGGAGGG
    GAGTGCTTCA TGGTGAAAGA CCTTTCAAAC CCCTCGAGAT ACTTGTGCAA GTGCCAACCT
    GGATTCACTG GAGCAAGATG TACTGAGAAT GTGCCCATGA AAGTCCAAAA CCAAGAAAAG
    GCGGAGGAGC TGTACCAGAA GAGAGTGCTG ACCATAACCG GCATCTGCAT CGCCCTCCTT
    GTGGTCGGCA TCATGTGTGT GGTGGCCTAC TGCAAAACCA AGAAACAGCG GAAAAAGCTG
    CATGACCGTC TTCGGCAGAG CCTTCGGTCT GAACGAAACA ATATGATGAA CATTGCCAAT
    GGGCCTCACC ATCCTAACCC ACCCCCCGAG AATGTCCAGC TGGTGAATCA ATACGTATCT
    AAAAACGTCA TCTCCAGTGA GCATATTGTT GAGAGAGAAG CAGAGACATC CTTTTCCACC
    AGTCACTATA CTTCCACAGC CCATCACTCC ACTACTGTCA CCCAGACTCC TAGCCACAGC
    TGGAGCAACG GACACACTGA AAGCATCCTT TCCGAAAGCC ACTCTGTAAT CGTGATGTCA
    TCCGTAGAAA ACAGTAGGCA CAGCAGCCCA ACTGGGGGCC CAAGAGGACG TCTTAATGGC
    ACAGGAGGCC CTCGTGAATG TAACAGCTTC CTCAGGCATG CCAGAGAAAC CCCTGATTCC
    TACCGAGACT CTCCTCATAG TGAAAGGTAT GTGTCAGCCA TGACCACCCC GGCTCGTATG
    TCACCTGTAG ATTTCCACAC GCCAAGCTCC CCCAAATCGC CCCCTTCGGA AATGTCTCCA
    CCCGTGTCCA GCATGACGGT GTCCATGCCT TCCATGGCGG TCAGCCCCTT CATGGAAGAA
    GAGAGACCTC TACTTCTCGT GACACCACCA AGGCTGCGGG AGAAGAAGTT TGACCATCAC
    CCTCAGCAGT TCAGCTCCTT CCACCACAAC CCCGCGCATG ACAGTAACAG CCTCCCTGCT
    AGCCCCTTGA GGATAGTGGA GGATGAGGAG TATGAAACGA CCCAAGAGTA CGAGCCAGCC
    CAAGAGCCTG TTAAGAAACT CGCCAATAGC CGGCGGGCCA AAAGAACCAA GCCCAATGGC
    CACATTGCTA ACAGATTGGA AGTGGACAGC AACACAAGCT CCCAGAGCAG TAACTCAGAG
    AGTGAAACAG AAGATGAAAG AGTAGGTGAA GATACGCCTT TCCTGGGCAT ACAGAACCCC
    CTGGCAGCCA GTCTTGAGGC AACACCTGCC TTCCGCCTGG CTGACAGCAG GACTAACCCA
    GCAGGCCGCT TCTCGACACA GGAAGAAATC CAGGCCAGGC TGTCTAGTGT AATTGCTAAC
    CAAGACCCTA TTGCTGTATA A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_024302911.1
    CDS518..2338
    Translation

    Target ORF information:

    RefSeq Version XM_024447143.1
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant X7, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_024447143.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG CTACATCTAC ATCCACCACT
    GGGACAAGCC ATCTTGTAAA ATGTGCGGAG AAGGAGAAAA CTTTCTGTGT GAATGGAGGG
    GAGTGCTTCA TGGTGAAAGA CCTTTCAAAC CCCTCGAGAT ACTTGTGCAA GTGCCAACCT
    GGATTCACTG GAGCAAGATG TACTGAGAAT GTGCCCATGA AAGTCCAAAA CCAAGAAAAG
    GCGGAGGAGC TGTACCAGAA GAGAGTGCTG ACCATAACCG GCATCTGCAT CGCCCTCCTT
    GTGGTCGGCA TCATGTGTGT GGTGGCCTAC TGCAAAACCA AGAAACAGCG GAAAAAGCTG
    CATGACCGTC TTCGGCAGAG CCTTCGGTCT GAACGAAACA ATATGATGAA CATTGCCAAT
    GGGCCTCACC ATCCTAACCC ACCCCCCGAG AATGTCCAGC TGGTGAATCA ATACGTATCT
    AAAAACGTCA TCTCCAGTGA GCATATTGTT GAGAGAGAAG CAGAGACATC CTTTTCCACC
    AGTCACTATA CTTCCACAGC CCATCACTCC ACTACTGTCA CCCAGACTCC TAGCCACAGC
    TGGAGCAACG GACACACTGA AAGCATCCTT TCCGAAAGCC ACTCTGTAAT CGTGATGTCA
    TCCGTAGAAA ACAGTAGGCA CAGCAGCCCA ACTGGGGGCC CAAGAGGACG TCTTAATGGC
    ACAGGAGGCC CTCGTGAATG TAACAGCTTC CTCAGGCATG CCAGAGAAAC CCCTGATTCC
    TACCGAGACT CTCCTCATAG TGAAAGGTAT GTGTCAGCCA TGACCACCCC GGCTCGTATG
    TCACCTGTAG ATTTCCACAC GCCAAGCTCC CCCAAATCGC CCCCTTCGGA AATGTCTCCA
    CCCGTGTCCA GCATGACGGT GTCCATGCCT TCCATGGCGG TCAGCCCCTT CATGGAAGAA
    GAGAGACCTC TACTTCTCGT GACACCACCA AGGCTGCGGG AGAAGAAGTT TGACCATCAC
    CCTCAGCAGT TCAGCTCCTT CCACCACAAC CCCGCGCATG ACAGTAACAG CCTCCCTGCT
    AGCCCCTTGA GGATAGTGGA GGATGAGGAG TATGAAACGA CCCAAGAGTA CGAGCCAGCC
    CAAGAGCCTG TTAAGAAACT CGCCAATAGC CGGCGGGCCA AAAGAACCAA GCCCAATGGC
    CACATTGCTA ACAGATTGGA AGTGGACAGC AACACAAGCT CCCAGAGCAG TAACTCAGAG
    AGTGAAACAG AAGATGAAAG AGTAGGTGAA GATACGCCTT TCCTGGGCAT ACAGAACCCC
    CTGGCAGCCA GTCTTGAGGC AACACCTGCC TTCCGCCTGG CTGACAGCAG GACTAACCCA
    GCAGGCCGCT TCTCGACACA GGAAGAAATC CAGGCCAGGC TGTCTAGTGT AATTGCTAAC
    CAAGACCCTA TTGCTGTATA A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu97933
    Clone ID Related Accession (Same CDS sequence) XM_017013365.1 , XM_017013365.2
    Accession Version XM_017013365.1 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1944bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2016-06-05
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform X3
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    ATGGAGCCCG ACGCCAACAG CACCAGCCGC GCGCCGGCCG CCTTCCGAGC CTCTTTCCCC 
    CCTCTGGAGA CGGGCCGGAA CCTCAAGAAG GAGGTCAGCC GGGTGCTGTG CAAGCGGTGC
    GCCTTGCCTC CCCGATTGAA AGAGATGAAA AGCCAGGAAT CGGCTGCAGG TTCCAAACTA
    GTCCTTCGGT GTGAAACCAG TTCTGAATAC TCCTCTCTCA GATTCAAGTG GTTCAAGAAT
    GGGAATGAAT TGAATCGAAA AAACAAACCA CAAAATATCA AGATACAAAA AAAGCCAGGG
    AAGTCAGAAC TTCGCATTAA CAAAGCATCA CTGGCTGATT CTGGAGAGTA TATGTGCAAA
    GTGATCAGCA AATTAGGAAA TGACAGTGCC TCTGCCAATA TCACCATCGT GGAATCAAAC
    GAGATCATCA CTGGTATGCC AGCCTCAACT GAAGGAGCAT ATGTGTCTTC AGAGTCTCCC
    ATTAGAATAT CAGTATCCAC AGAAGGAGCA AATACTTCTT CATCTACATC TACATCCACC
    ACTGGGACAA GCCATCTTGT AAAATGTGCG GAGAAGGAGA AAACTTTCTG TGTGAATGGA
    GGGGAGTGCT TCATGGTGAA AGACCTTTCA AACCCCTCGA GATACTTGTG CAAGTGCCAA
    CCTGGATTCA CTGGAGCAAG ATGTACTGAG AATGTGCCCA TGAAAGTCCA AAACCAAGAA
    AAGGCGGAGG AGCTGTACCA GAAGAGAGTG CTGACCATAA CCGGCATCTG CATCGCCCTC
    CTTGTGGTCG GCATCATGTG TGTGGTGGCC TACTGCAAAA CCAAGAAACA GCGGAAAAAG
    CTGCATGACC GTCTTCGGCA GAGCCTTCGG TCTGAACGAA ACAATATGAT GAACATTGCC
    AATGGGCCTC ACCATCCTAA CCCACCCCCC GAGAATGTCC AGCTGGTGAA TCAATACGTA
    TCTAAAAACG TCATCTCCAG TGAGCATATT GTTGAGAGAG AAGCAGAGAC ATCCTTTTCC
    ACCAGTCACT ATACTTCCAC AGCCCATCAC TCCACTACTG TCACCCAGAC TCCTAGCCAC
    AGCTGGAGCA ACGGACACAC TGAAAGCATC CTTTCCGAAA GCCACTCTGT AATCGTGATG
    TCATCCGTAG AAAACAGTAG GCACAGCAGC CCAACTGGGG GCCCAAGAGG ACGTCTTAAT
    GGCACAGGAG GCCCTCGTGA ATGTAACAGC TTCCTCAGGC ATGCCAGAGA AACCCCTGAT
    TCCTACCGAG ACTCTCCTCA TAGTGAAAGG TATGTGTCAG CCATGACCAC CCCGGCTCGT
    ATGTCACCTG TAGATTTCCA CACGCCAAGC TCCCCCAAAT CGCCCCCTTC GGAAATGTCT
    CCACCCGTGT CCAGCATGAC GGTGTCCATG CCTTCCATGG CGGTCAGCCC CTTCATGGAA
    GAAGAGAGAC CTCTACTTCT CGTGACACCA CCAAGGCTGC GGGAGAAGAA GTTTGACCAT
    CACCCTCAGC AGTTCAGCTC CTTCCACCAC AACCCCGCGC ATGACAGTAA CAGCCTCCCT
    GCTAGCCCCT TGAGGATAGT GGAGGATGAG GAGTATGAAA CGACCCAAGA GTACGAGCCA
    GCCCAAGAGC CTGTTAAGAA ACTCGCCAAT AGCCGGCGGG CCAAAAGAAC CAAGCCCAAT
    GGCCACATTG CTAACAGATT GGAAGTGGAC AGCAACACAA GCTCCCAGAG CAGTAACTCA
    GAGAGTGAAA CAGAAGATGA AAGAGTAGGT GAAGATACGC CTTTCCTGGG CATACAGAAC
    CCCCTGGCAG CCAGTCTTGA GGCAACACCT GCCTTCCGCC TGGCTGACAG CAGGACTAAC
    CCAGCAGGCC GCTTCTCGAC ACAGGAAGAA ATCCAGGCCA GGCTGTCTAG TGTAATTGCT
    AACCAAGACC CTATTGCTGT ATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_016868854.1
    CDS209..2152
    Translation

    Target ORF information:

    RefSeq Version XM_017013365.1
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant X3, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_017013365.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    ATGGAGCCCG ACGCCAACAG CACCAGCCGC GCGCCGGCCG CCTTCCGAGC CTCTTTCCCC 
    CCTCTGGAGA CGGGCCGGAA CCTCAAGAAG GAGGTCAGCC GGGTGCTGTG CAAGCGGTGC
    GCCTTGCCTC CCCGATTGAA AGAGATGAAA AGCCAGGAAT CGGCTGCAGG TTCCAAACTA
    GTCCTTCGGT GTGAAACCAG TTCTGAATAC TCCTCTCTCA GATTCAAGTG GTTCAAGAAT
    GGGAATGAAT TGAATCGAAA AAACAAACCA CAAAATATCA AGATACAAAA AAAGCCAGGG
    AAGTCAGAAC TTCGCATTAA CAAAGCATCA CTGGCTGATT CTGGAGAGTA TATGTGCAAA
    GTGATCAGCA AATTAGGAAA TGACAGTGCC TCTGCCAATA TCACCATCGT GGAATCAAAC
    GAGATCATCA CTGGTATGCC AGCCTCAACT GAAGGAGCAT ATGTGTCTTC AGAGTCTCCC
    ATTAGAATAT CAGTATCCAC AGAAGGAGCA AATACTTCTT CATCTACATC TACATCCACC
    ACTGGGACAA GCCATCTTGT AAAATGTGCG GAGAAGGAGA AAACTTTCTG TGTGAATGGA
    GGGGAGTGCT TCATGGTGAA AGACCTTTCA AACCCCTCGA GATACTTGTG CAAGTGCCAA
    CCTGGATTCA CTGGAGCAAG ATGTACTGAG AATGTGCCCA TGAAAGTCCA AAACCAAGAA
    AAGGCGGAGG AGCTGTACCA GAAGAGAGTG CTGACCATAA CCGGCATCTG CATCGCCCTC
    CTTGTGGTCG GCATCATGTG TGTGGTGGCC TACTGCAAAA CCAAGAAACA GCGGAAAAAG
    CTGCATGACC GTCTTCGGCA GAGCCTTCGG TCTGAACGAA ACAATATGAT GAACATTGCC
    AATGGGCCTC ACCATCCTAA CCCACCCCCC GAGAATGTCC AGCTGGTGAA TCAATACGTA
    TCTAAAAACG TCATCTCCAG TGAGCATATT GTTGAGAGAG AAGCAGAGAC ATCCTTTTCC
    ACCAGTCACT ATACTTCCAC AGCCCATCAC TCCACTACTG TCACCCAGAC TCCTAGCCAC
    AGCTGGAGCA ACGGACACAC TGAAAGCATC CTTTCCGAAA GCCACTCTGT AATCGTGATG
    TCATCCGTAG AAAACAGTAG GCACAGCAGC CCAACTGGGG GCCCAAGAGG ACGTCTTAAT
    GGCACAGGAG GCCCTCGTGA ATGTAACAGC TTCCTCAGGC ATGCCAGAGA AACCCCTGAT
    TCCTACCGAG ACTCTCCTCA TAGTGAAAGG TATGTGTCAG CCATGACCAC CCCGGCTCGT
    ATGTCACCTG TAGATTTCCA CACGCCAAGC TCCCCCAAAT CGCCCCCTTC GGAAATGTCT
    CCACCCGTGT CCAGCATGAC GGTGTCCATG CCTTCCATGG CGGTCAGCCC CTTCATGGAA
    GAAGAGAGAC CTCTACTTCT CGTGACACCA CCAAGGCTGC GGGAGAAGAA GTTTGACCAT
    CACCCTCAGC AGTTCAGCTC CTTCCACCAC AACCCCGCGC ATGACAGTAA CAGCCTCCCT
    GCTAGCCCCT TGAGGATAGT GGAGGATGAG GAGTATGAAA CGACCCAAGA GTACGAGCCA
    GCCCAAGAGC CTGTTAAGAA ACTCGCCAAT AGCCGGCGGG CCAAAAGAAC CAAGCCCAAT
    GGCCACATTG CTAACAGATT GGAAGTGGAC AGCAACACAA GCTCCCAGAG CAGTAACTCA
    GAGAGTGAAA CAGAAGATGA AAGAGTAGGT GAAGATACGC CTTTCCTGGG CATACAGAAC
    CCCCTGGCAG CCAGTCTTGA GGCAACACCT GCCTTCCGCC TGGCTGACAG CAGGACTAAC
    CCAGCAGGCC GCTTCTCGAC ACAGGAAGAA ATCCAGGCCA GGCTGTCTAG TGTAATTGCT
    AACCAAGACC CTATTGCTGT ATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu97933
    Clone ID Related Accession (Same CDS sequence) XM_017013365.1 , XM_017013365.2
    Accession Version XM_017013365.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1944bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-05
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform X3
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017013365.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    ATGGAGCCCG ACGCCAACAG CACCAGCCGC GCGCCGGCCG CCTTCCGAGC CTCTTTCCCC 
    CCTCTGGAGA CGGGCCGGAA CCTCAAGAAG GAGGTCAGCC GGGTGCTGTG CAAGCGGTGC
    GCCTTGCCTC CCCGATTGAA AGAGATGAAA AGCCAGGAAT CGGCTGCAGG TTCCAAACTA
    GTCCTTCGGT GTGAAACCAG TTCTGAATAC TCCTCTCTCA GATTCAAGTG GTTCAAGAAT
    GGGAATGAAT TGAATCGAAA AAACAAACCA CAAAATATCA AGATACAAAA AAAGCCAGGG
    AAGTCAGAAC TTCGCATTAA CAAAGCATCA CTGGCTGATT CTGGAGAGTA TATGTGCAAA
    GTGATCAGCA AATTAGGAAA TGACAGTGCC TCTGCCAATA TCACCATCGT GGAATCAAAC
    GAGATCATCA CTGGTATGCC AGCCTCAACT GAAGGAGCAT ATGTGTCTTC AGAGTCTCCC
    ATTAGAATAT CAGTATCCAC AGAAGGAGCA AATACTTCTT CATCTACATC TACATCCACC
    ACTGGGACAA GCCATCTTGT AAAATGTGCG GAGAAGGAGA AAACTTTCTG TGTGAATGGA
    GGGGAGTGCT TCATGGTGAA AGACCTTTCA AACCCCTCGA GATACTTGTG CAAGTGCCAA
    CCTGGATTCA CTGGAGCAAG ATGTACTGAG AATGTGCCCA TGAAAGTCCA AAACCAAGAA
    AAGGCGGAGG AGCTGTACCA GAAGAGAGTG CTGACCATAA CCGGCATCTG CATCGCCCTC
    CTTGTGGTCG GCATCATGTG TGTGGTGGCC TACTGCAAAA CCAAGAAACA GCGGAAAAAG
    CTGCATGACC GTCTTCGGCA GAGCCTTCGG TCTGAACGAA ACAATATGAT GAACATTGCC
    AATGGGCCTC ACCATCCTAA CCCACCCCCC GAGAATGTCC AGCTGGTGAA TCAATACGTA
    TCTAAAAACG TCATCTCCAG TGAGCATATT GTTGAGAGAG AAGCAGAGAC ATCCTTTTCC
    ACCAGTCACT ATACTTCCAC AGCCCATCAC TCCACTACTG TCACCCAGAC TCCTAGCCAC
    AGCTGGAGCA ACGGACACAC TGAAAGCATC CTTTCCGAAA GCCACTCTGT AATCGTGATG
    TCATCCGTAG AAAACAGTAG GCACAGCAGC CCAACTGGGG GCCCAAGAGG ACGTCTTAAT
    GGCACAGGAG GCCCTCGTGA ATGTAACAGC TTCCTCAGGC ATGCCAGAGA AACCCCTGAT
    TCCTACCGAG ACTCTCCTCA TAGTGAAAGG TATGTGTCAG CCATGACCAC CCCGGCTCGT
    ATGTCACCTG TAGATTTCCA CACGCCAAGC TCCCCCAAAT CGCCCCCTTC GGAAATGTCT
    CCACCCGTGT CCAGCATGAC GGTGTCCATG CCTTCCATGG CGGTCAGCCC CTTCATGGAA
    GAAGAGAGAC CTCTACTTCT CGTGACACCA CCAAGGCTGC GGGAGAAGAA GTTTGACCAT
    CACCCTCAGC AGTTCAGCTC CTTCCACCAC AACCCCGCGC ATGACAGTAA CAGCCTCCCT
    GCTAGCCCCT TGAGGATAGT GGAGGATGAG GAGTATGAAA CGACCCAAGA GTACGAGCCA
    GCCCAAGAGC CTGTTAAGAA ACTCGCCAAT AGCCGGCGGG CCAAAAGAAC CAAGCCCAAT
    GGCCACATTG CTAACAGATT GGAAGTGGAC AGCAACACAA GCTCCCAGAG CAGTAACTCA
    GAGAGTGAAA CAGAAGATGA AAGAGTAGGT GAAGATACGC CTTTCCTGGG CATACAGAAC
    CCCCTGGCAG CCAGTCTTGA GGCAACACCT GCCTTCCGCC TGGCTGACAG CAGGACTAAC
    CCAGCAGGCC GCTTCTCGAC ACAGGAAGAA ATCCAGGCCA GGCTGTCTAG TGTAATTGCT
    AACCAAGACC CTATTGCTGT ATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_016868854.1
    CDS245..2188
    Translation

    Target ORF information:

    RefSeq Version XM_017013365.2
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant X3, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_017013365.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    ATGGAGCCCG ACGCCAACAG CACCAGCCGC GCGCCGGCCG CCTTCCGAGC CTCTTTCCCC 
    CCTCTGGAGA CGGGCCGGAA CCTCAAGAAG GAGGTCAGCC GGGTGCTGTG CAAGCGGTGC
    GCCTTGCCTC CCCGATTGAA AGAGATGAAA AGCCAGGAAT CGGCTGCAGG TTCCAAACTA
    GTCCTTCGGT GTGAAACCAG TTCTGAATAC TCCTCTCTCA GATTCAAGTG GTTCAAGAAT
    GGGAATGAAT TGAATCGAAA AAACAAACCA CAAAATATCA AGATACAAAA AAAGCCAGGG
    AAGTCAGAAC TTCGCATTAA CAAAGCATCA CTGGCTGATT CTGGAGAGTA TATGTGCAAA
    GTGATCAGCA AATTAGGAAA TGACAGTGCC TCTGCCAATA TCACCATCGT GGAATCAAAC
    GAGATCATCA CTGGTATGCC AGCCTCAACT GAAGGAGCAT ATGTGTCTTC AGAGTCTCCC
    ATTAGAATAT CAGTATCCAC AGAAGGAGCA AATACTTCTT CATCTACATC TACATCCACC
    ACTGGGACAA GCCATCTTGT AAAATGTGCG GAGAAGGAGA AAACTTTCTG TGTGAATGGA
    GGGGAGTGCT TCATGGTGAA AGACCTTTCA AACCCCTCGA GATACTTGTG CAAGTGCCAA
    CCTGGATTCA CTGGAGCAAG ATGTACTGAG AATGTGCCCA TGAAAGTCCA AAACCAAGAA
    AAGGCGGAGG AGCTGTACCA GAAGAGAGTG CTGACCATAA CCGGCATCTG CATCGCCCTC
    CTTGTGGTCG GCATCATGTG TGTGGTGGCC TACTGCAAAA CCAAGAAACA GCGGAAAAAG
    CTGCATGACC GTCTTCGGCA GAGCCTTCGG TCTGAACGAA ACAATATGAT GAACATTGCC
    AATGGGCCTC ACCATCCTAA CCCACCCCCC GAGAATGTCC AGCTGGTGAA TCAATACGTA
    TCTAAAAACG TCATCTCCAG TGAGCATATT GTTGAGAGAG AAGCAGAGAC ATCCTTTTCC
    ACCAGTCACT ATACTTCCAC AGCCCATCAC TCCACTACTG TCACCCAGAC TCCTAGCCAC
    AGCTGGAGCA ACGGACACAC TGAAAGCATC CTTTCCGAAA GCCACTCTGT AATCGTGATG
    TCATCCGTAG AAAACAGTAG GCACAGCAGC CCAACTGGGG GCCCAAGAGG ACGTCTTAAT
    GGCACAGGAG GCCCTCGTGA ATGTAACAGC TTCCTCAGGC ATGCCAGAGA AACCCCTGAT
    TCCTACCGAG ACTCTCCTCA TAGTGAAAGG TATGTGTCAG CCATGACCAC CCCGGCTCGT
    ATGTCACCTG TAGATTTCCA CACGCCAAGC TCCCCCAAAT CGCCCCCTTC GGAAATGTCT
    CCACCCGTGT CCAGCATGAC GGTGTCCATG CCTTCCATGG CGGTCAGCCC CTTCATGGAA
    GAAGAGAGAC CTCTACTTCT CGTGACACCA CCAAGGCTGC GGGAGAAGAA GTTTGACCAT
    CACCCTCAGC AGTTCAGCTC CTTCCACCAC AACCCCGCGC ATGACAGTAA CAGCCTCCCT
    GCTAGCCCCT TGAGGATAGT GGAGGATGAG GAGTATGAAA CGACCCAAGA GTACGAGCCA
    GCCCAAGAGC CTGTTAAGAA ACTCGCCAAT AGCCGGCGGG CCAAAAGAAC CAAGCCCAAT
    GGCCACATTG CTAACAGATT GGAAGTGGAC AGCAACACAA GCTCCCAGAG CAGTAACTCA
    GAGAGTGAAA CAGAAGATGA AAGAGTAGGT GAAGATACGC CTTTCCTGGG CATACAGAAC
    CCCCTGGCAG CCAGTCTTGA GGCAACACCT GCCTTCCGCC TGGCTGACAG CAGGACTAAC
    CCAGCAGGCC GCTTCTCGAC ACAGGAAGAA ATCCAGGCCA GGCTGTCTAG TGTAATTGCT
    AACCAAGACC CTATTGCTGT ATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu97934
    Clone ID Related Accession (Same CDS sequence) XM_017013366.1 , XM_017013366.2
    Accession Version XM_017013366.1 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1935bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2016-06-05
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform X4
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    ATGGAGCCCG ACGCCAACAG CACCAGCCGC GCGCCGGCCG CCTTCCGAGC CTCTTTCCCC 
    CCTCTGGAGA CGGGCCGGAA CCTCAAGAAG GAGGTCAGCC GGGTGCTGTG CAAGCGGTGC
    GCCTTGCCTC CCCGATTGAA AGAGATGAAA AGCCAGGAAT CGGCTGCAGG TTCCAAACTA
    GTCCTTCGGT GTGAAACCAG TTCTGAATAC TCCTCTCTCA GATTCAAGTG GTTCAAGAAT
    GGGAATGAAT TGAATCGAAA AAACAAACCA CAAAATATCA AGATACAAAA AAAGCCAGGG
    AAGTCAGAAC TTCGCATTAA CAAAGCATCA CTGGCTGATT CTGGAGAGTA TATGTGCAAA
    GTGATCAGCA AATTAGGAAA TGACAGTGCC TCTGCCAATA TCACCATCGT GGAATCAAAC
    GAGATCATCA CTGGTATGCC AGCCTCAACT GAAGGAGCAT ATGTGTCTTC AGAGTCTCCC
    ATTAGAATAT CAGTATCCAC AGAAGGAGCA AATACTTCTT CATCTACATC TACATCCACC
    ACTGGGACAA GCCATCTTGT AAAATGTGCG GAGAAGGAGA AAACTTTCTG TGTGAATGGA
    GGGGAGTGCT TCATGGTGAA AGACCTTTCA AACCCCTCGA GATACTTGTG CAAGTGCCCA
    AATGAGTTTA CTGGTGATCG CTGCCAAAAC TACGTAATGG CCAGCTTCTA CAAGGCGGAG
    GAGCTGTACC AGAAGAGAGT GCTGACCATA ACCGGCATCT GCATCGCCCT CCTTGTGGTC
    GGCATCATGT GTGTGGTGGC CTACTGCAAA ACCAAGAAAC AGCGGAAAAA GCTGCATGAC
    CGTCTTCGGC AGAGCCTTCG GTCTGAACGA AACAATATGA TGAACATTGC CAATGGGCCT
    CACCATCCTA ACCCACCCCC CGAGAATGTC CAGCTGGTGA ATCAATACGT ATCTAAAAAC
    GTCATCTCCA GTGAGCATAT TGTTGAGAGA GAAGCAGAGA CATCCTTTTC CACCAGTCAC
    TATACTTCCA CAGCCCATCA CTCCACTACT GTCACCCAGA CTCCTAGCCA CAGCTGGAGC
    AACGGACACA CTGAAAGCAT CCTTTCCGAA AGCCACTCTG TAATCGTGAT GTCATCCGTA
    GAAAACAGTA GGCACAGCAG CCCAACTGGG GGCCCAAGAG GACGTCTTAA TGGCACAGGA
    GGCCCTCGTG AATGTAACAG CTTCCTCAGG CATGCCAGAG AAACCCCTGA TTCCTACCGA
    GACTCTCCTC ATAGTGAAAG GTATGTGTCA GCCATGACCA CCCCGGCTCG TATGTCACCT
    GTAGATTTCC ACACGCCAAG CTCCCCCAAA TCGCCCCCTT CGGAAATGTC TCCACCCGTG
    TCCAGCATGA CGGTGTCCAT GCCTTCCATG GCGGTCAGCC CCTTCATGGA AGAAGAGAGA
    CCTCTACTTC TCGTGACACC ACCAAGGCTG CGGGAGAAGA AGTTTGACCA TCACCCTCAG
    CAGTTCAGCT CCTTCCACCA CAACCCCGCG CATGACAGTA ACAGCCTCCC TGCTAGCCCC
    TTGAGGATAG TGGAGGATGA GGAGTATGAA ACGACCCAAG AGTACGAGCC AGCCCAAGAG
    CCTGTTAAGA AACTCGCCAA TAGCCGGCGG GCCAAAAGAA CCAAGCCCAA TGGCCACATT
    GCTAACAGAT TGGAAGTGGA CAGCAACACA AGCTCCCAGA GCAGTAACTC AGAGAGTGAA
    ACAGAAGATG AAAGAGTAGG TGAAGATACG CCTTTCCTGG GCATACAGAA CCCCCTGGCA
    GCCAGTCTTG AGGCAACACC TGCCTTCCGC CTGGCTGACA GCAGGACTAA CCCAGCAGGC
    CGCTTCTCGA CACAGGAAGA AATCCAGGCC AGGCTGTCTA GTGTAATTGC TAACCAAGAC
    CCTATTGCTG TATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_016868855.1
    CDS209..2143
    Translation

    Target ORF information:

    RefSeq Version XM_017013366.1
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant X4, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_017013366.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    ATGGAGCCCG ACGCCAACAG CACCAGCCGC GCGCCGGCCG CCTTCCGAGC CTCTTTCCCC 
    CCTCTGGAGA CGGGCCGGAA CCTCAAGAAG GAGGTCAGCC GGGTGCTGTG CAAGCGGTGC
    GCCTTGCCTC CCCGATTGAA AGAGATGAAA AGCCAGGAAT CGGCTGCAGG TTCCAAACTA
    GTCCTTCGGT GTGAAACCAG TTCTGAATAC TCCTCTCTCA GATTCAAGTG GTTCAAGAAT
    GGGAATGAAT TGAATCGAAA AAACAAACCA CAAAATATCA AGATACAAAA AAAGCCAGGG
    AAGTCAGAAC TTCGCATTAA CAAAGCATCA CTGGCTGATT CTGGAGAGTA TATGTGCAAA
    GTGATCAGCA AATTAGGAAA TGACAGTGCC TCTGCCAATA TCACCATCGT GGAATCAAAC
    GAGATCATCA CTGGTATGCC AGCCTCAACT GAAGGAGCAT ATGTGTCTTC AGAGTCTCCC
    ATTAGAATAT CAGTATCCAC AGAAGGAGCA AATACTTCTT CATCTACATC TACATCCACC
    ACTGGGACAA GCCATCTTGT AAAATGTGCG GAGAAGGAGA AAACTTTCTG TGTGAATGGA
    GGGGAGTGCT TCATGGTGAA AGACCTTTCA AACCCCTCGA GATACTTGTG CAAGTGCCCA
    AATGAGTTTA CTGGTGATCG CTGCCAAAAC TACGTAATGG CCAGCTTCTA CAAGGCGGAG
    GAGCTGTACC AGAAGAGAGT GCTGACCATA ACCGGCATCT GCATCGCCCT CCTTGTGGTC
    GGCATCATGT GTGTGGTGGC CTACTGCAAA ACCAAGAAAC AGCGGAAAAA GCTGCATGAC
    CGTCTTCGGC AGAGCCTTCG GTCTGAACGA AACAATATGA TGAACATTGC CAATGGGCCT
    CACCATCCTA ACCCACCCCC CGAGAATGTC CAGCTGGTGA ATCAATACGT ATCTAAAAAC
    GTCATCTCCA GTGAGCATAT TGTTGAGAGA GAAGCAGAGA CATCCTTTTC CACCAGTCAC
    TATACTTCCA CAGCCCATCA CTCCACTACT GTCACCCAGA CTCCTAGCCA CAGCTGGAGC
    AACGGACACA CTGAAAGCAT CCTTTCCGAA AGCCACTCTG TAATCGTGAT GTCATCCGTA
    GAAAACAGTA GGCACAGCAG CCCAACTGGG GGCCCAAGAG GACGTCTTAA TGGCACAGGA
    GGCCCTCGTG AATGTAACAG CTTCCTCAGG CATGCCAGAG AAACCCCTGA TTCCTACCGA
    GACTCTCCTC ATAGTGAAAG GTATGTGTCA GCCATGACCA CCCCGGCTCG TATGTCACCT
    GTAGATTTCC ACACGCCAAG CTCCCCCAAA TCGCCCCCTT CGGAAATGTC TCCACCCGTG
    TCCAGCATGA CGGTGTCCAT GCCTTCCATG GCGGTCAGCC CCTTCATGGA AGAAGAGAGA
    CCTCTACTTC TCGTGACACC ACCAAGGCTG CGGGAGAAGA AGTTTGACCA TCACCCTCAG
    CAGTTCAGCT CCTTCCACCA CAACCCCGCG CATGACAGTA ACAGCCTCCC TGCTAGCCCC
    TTGAGGATAG TGGAGGATGA GGAGTATGAA ACGACCCAAG AGTACGAGCC AGCCCAAGAG
    CCTGTTAAGA AACTCGCCAA TAGCCGGCGG GCCAAAAGAA CCAAGCCCAA TGGCCACATT
    GCTAACAGAT TGGAAGTGGA CAGCAACACA AGCTCCCAGA GCAGTAACTC AGAGAGTGAA
    ACAGAAGATG AAAGAGTAGG TGAAGATACG CCTTTCCTGG GCATACAGAA CCCCCTGGCA
    GCCAGTCTTG AGGCAACACC TGCCTTCCGC CTGGCTGACA GCAGGACTAA CCCAGCAGGC
    CGCTTCTCGA CACAGGAAGA AATCCAGGCC AGGCTGTCTA GTGTAATTGC TAACCAAGAC
    CCTATTGCTG TATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu97934
    Clone ID Related Accession (Same CDS sequence) XM_017013366.1 , XM_017013366.2
    Accession Version XM_017013366.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1935bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-05
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform X4
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017013366.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    ATGGAGCCCG ACGCCAACAG CACCAGCCGC GCGCCGGCCG CCTTCCGAGC CTCTTTCCCC 
    CCTCTGGAGA CGGGCCGGAA CCTCAAGAAG GAGGTCAGCC GGGTGCTGTG CAAGCGGTGC
    GCCTTGCCTC CCCGATTGAA AGAGATGAAA AGCCAGGAAT CGGCTGCAGG TTCCAAACTA
    GTCCTTCGGT GTGAAACCAG TTCTGAATAC TCCTCTCTCA GATTCAAGTG GTTCAAGAAT
    GGGAATGAAT TGAATCGAAA AAACAAACCA CAAAATATCA AGATACAAAA AAAGCCAGGG
    AAGTCAGAAC TTCGCATTAA CAAAGCATCA CTGGCTGATT CTGGAGAGTA TATGTGCAAA
    GTGATCAGCA AATTAGGAAA TGACAGTGCC TCTGCCAATA TCACCATCGT GGAATCAAAC
    GAGATCATCA CTGGTATGCC AGCCTCAACT GAAGGAGCAT ATGTGTCTTC AGAGTCTCCC
    ATTAGAATAT CAGTATCCAC AGAAGGAGCA AATACTTCTT CATCTACATC TACATCCACC
    ACTGGGACAA GCCATCTTGT AAAATGTGCG GAGAAGGAGA AAACTTTCTG TGTGAATGGA
    GGGGAGTGCT TCATGGTGAA AGACCTTTCA AACCCCTCGA GATACTTGTG CAAGTGCCCA
    AATGAGTTTA CTGGTGATCG CTGCCAAAAC TACGTAATGG CCAGCTTCTA CAAGGCGGAG
    GAGCTGTACC AGAAGAGAGT GCTGACCATA ACCGGCATCT GCATCGCCCT CCTTGTGGTC
    GGCATCATGT GTGTGGTGGC CTACTGCAAA ACCAAGAAAC AGCGGAAAAA GCTGCATGAC
    CGTCTTCGGC AGAGCCTTCG GTCTGAACGA AACAATATGA TGAACATTGC CAATGGGCCT
    CACCATCCTA ACCCACCCCC CGAGAATGTC CAGCTGGTGA ATCAATACGT ATCTAAAAAC
    GTCATCTCCA GTGAGCATAT TGTTGAGAGA GAAGCAGAGA CATCCTTTTC CACCAGTCAC
    TATACTTCCA CAGCCCATCA CTCCACTACT GTCACCCAGA CTCCTAGCCA CAGCTGGAGC
    AACGGACACA CTGAAAGCAT CCTTTCCGAA AGCCACTCTG TAATCGTGAT GTCATCCGTA
    GAAAACAGTA GGCACAGCAG CCCAACTGGG GGCCCAAGAG GACGTCTTAA TGGCACAGGA
    GGCCCTCGTG AATGTAACAG CTTCCTCAGG CATGCCAGAG AAACCCCTGA TTCCTACCGA
    GACTCTCCTC ATAGTGAAAG GTATGTGTCA GCCATGACCA CCCCGGCTCG TATGTCACCT
    GTAGATTTCC ACACGCCAAG CTCCCCCAAA TCGCCCCCTT CGGAAATGTC TCCACCCGTG
    TCCAGCATGA CGGTGTCCAT GCCTTCCATG GCGGTCAGCC CCTTCATGGA AGAAGAGAGA
    CCTCTACTTC TCGTGACACC ACCAAGGCTG CGGGAGAAGA AGTTTGACCA TCACCCTCAG
    CAGTTCAGCT CCTTCCACCA CAACCCCGCG CATGACAGTA ACAGCCTCCC TGCTAGCCCC
    TTGAGGATAG TGGAGGATGA GGAGTATGAA ACGACCCAAG AGTACGAGCC AGCCCAAGAG
    CCTGTTAAGA AACTCGCCAA TAGCCGGCGG GCCAAAAGAA CCAAGCCCAA TGGCCACATT
    GCTAACAGAT TGGAAGTGGA CAGCAACACA AGCTCCCAGA GCAGTAACTC AGAGAGTGAA
    ACAGAAGATG AAAGAGTAGG TGAAGATACG CCTTTCCTGG GCATACAGAA CCCCCTGGCA
    GCCAGTCTTG AGGCAACACC TGCCTTCCGC CTGGCTGACA GCAGGACTAA CCCAGCAGGC
    CGCTTCTCGA CACAGGAAGA AATCCAGGCC AGGCTGTCTA GTGTAATTGC TAACCAAGAC
    CCTATTGCTG TATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_016868855.1
    CDS245..2179
    Translation

    Target ORF information:

    RefSeq Version XM_017013366.2
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant X4, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_017013366.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    ATGGAGCCCG ACGCCAACAG CACCAGCCGC GCGCCGGCCG CCTTCCGAGC CTCTTTCCCC 
    CCTCTGGAGA CGGGCCGGAA CCTCAAGAAG GAGGTCAGCC GGGTGCTGTG CAAGCGGTGC
    GCCTTGCCTC CCCGATTGAA AGAGATGAAA AGCCAGGAAT CGGCTGCAGG TTCCAAACTA
    GTCCTTCGGT GTGAAACCAG TTCTGAATAC TCCTCTCTCA GATTCAAGTG GTTCAAGAAT
    GGGAATGAAT TGAATCGAAA AAACAAACCA CAAAATATCA AGATACAAAA AAAGCCAGGG
    AAGTCAGAAC TTCGCATTAA CAAAGCATCA CTGGCTGATT CTGGAGAGTA TATGTGCAAA
    GTGATCAGCA AATTAGGAAA TGACAGTGCC TCTGCCAATA TCACCATCGT GGAATCAAAC
    GAGATCATCA CTGGTATGCC AGCCTCAACT GAAGGAGCAT ATGTGTCTTC AGAGTCTCCC
    ATTAGAATAT CAGTATCCAC AGAAGGAGCA AATACTTCTT CATCTACATC TACATCCACC
    ACTGGGACAA GCCATCTTGT AAAATGTGCG GAGAAGGAGA AAACTTTCTG TGTGAATGGA
    GGGGAGTGCT TCATGGTGAA AGACCTTTCA AACCCCTCGA GATACTTGTG CAAGTGCCCA
    AATGAGTTTA CTGGTGATCG CTGCCAAAAC TACGTAATGG CCAGCTTCTA CAAGGCGGAG
    GAGCTGTACC AGAAGAGAGT GCTGACCATA ACCGGCATCT GCATCGCCCT CCTTGTGGTC
    GGCATCATGT GTGTGGTGGC CTACTGCAAA ACCAAGAAAC AGCGGAAAAA GCTGCATGAC
    CGTCTTCGGC AGAGCCTTCG GTCTGAACGA AACAATATGA TGAACATTGC CAATGGGCCT
    CACCATCCTA ACCCACCCCC CGAGAATGTC CAGCTGGTGA ATCAATACGT ATCTAAAAAC
    GTCATCTCCA GTGAGCATAT TGTTGAGAGA GAAGCAGAGA CATCCTTTTC CACCAGTCAC
    TATACTTCCA CAGCCCATCA CTCCACTACT GTCACCCAGA CTCCTAGCCA CAGCTGGAGC
    AACGGACACA CTGAAAGCAT CCTTTCCGAA AGCCACTCTG TAATCGTGAT GTCATCCGTA
    GAAAACAGTA GGCACAGCAG CCCAACTGGG GGCCCAAGAG GACGTCTTAA TGGCACAGGA
    GGCCCTCGTG AATGTAACAG CTTCCTCAGG CATGCCAGAG AAACCCCTGA TTCCTACCGA
    GACTCTCCTC ATAGTGAAAG GTATGTGTCA GCCATGACCA CCCCGGCTCG TATGTCACCT
    GTAGATTTCC ACACGCCAAG CTCCCCCAAA TCGCCCCCTT CGGAAATGTC TCCACCCGTG
    TCCAGCATGA CGGTGTCCAT GCCTTCCATG GCGGTCAGCC CCTTCATGGA AGAAGAGAGA
    CCTCTACTTC TCGTGACACC ACCAAGGCTG CGGGAGAAGA AGTTTGACCA TCACCCTCAG
    CAGTTCAGCT CCTTCCACCA CAACCCCGCG CATGACAGTA ACAGCCTCCC TGCTAGCCCC
    TTGAGGATAG TGGAGGATGA GGAGTATGAA ACGACCCAAG AGTACGAGCC AGCCCAAGAG
    CCTGTTAAGA AACTCGCCAA TAGCCGGCGG GCCAAAAGAA CCAAGCCCAA TGGCCACATT
    GCTAACAGAT TGGAAGTGGA CAGCAACACA AGCTCCCAGA GCAGTAACTC AGAGAGTGAA
    ACAGAAGATG AAAGAGTAGG TGAAGATACG CCTTTCCTGG GCATACAGAA CCCCCTGGCA
    GCCAGTCTTG AGGCAACACC TGCCTTCCGC CTGGCTGACA GCAGGACTAA CCCAGCAGGC
    CGCTTCTCGA CACAGGAAGA AATCCAGGCC AGGCTGTCTA GTGTAATTGC TAACCAAGAC
    CCTATTGCTG TATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu97935
    Clone ID Related Accession (Same CDS sequence) XM_017013367.1
    Accession Version XM_017013367.1 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1857bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-05
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform X5
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    ATGGAGCCCG ACGCCAACAG CACCAGCCGC GCGCCGGCCG CCTTCCGAGC CTCTTTCCCC 
    CCTCTGGAGA CGGGCCGGAA CCTCAAGAAG GAGGTCAGCC GGGTGCTGTG CAAGCGGTGC
    GCCTTGCCTC CCCGATTGAA AGAGATGAAA AGCCAGGAAT CGGCTGCAGG TTCCAAACTA
    GTCCTTCGGT GTGAAACCAG TTCTGAATAC TCCTCTCTCA GATTCAAGTG GTTCAAGAAT
    GGGAATGAAT TGAATCGAAA AAACAAACCA CAAAATATCA AGATACAAAA AAAGCCAGGG
    AAGTCAGAAC TTCGCATTAA CAAAGCATCA CTGGCTGATT CTGGAGAGTA TATGTGCAAA
    GTGATCAGCA AATTAGGAAA TGACAGTGCC TCTGCCAATA TCACCATCGT GGAATCAAAC
    GCTACATCTA CATCCACCAC TGGGACAAGC CATCTTGTAA AATGTGCGGA GAAGGAGAAA
    ACTTTCTGTG TGAATGGAGG GGAGTGCTTC ATGGTGAAAG ACCTTTCAAA CCCCTCGAGA
    TACTTGTGCA AGTGCCCAAA TGAGTTTACT GGTGATCGCT GCCAAAACTA CGTAATGGCC
    AGCTTCTACA AGCATCTTGG GATTGAATTT ATGGAGGCGG AGGAGCTGTA CCAGAAGAGA
    GTGCTGACCA TAACCGGCAT CTGCATCGCC CTCCTTGTGG TCGGCATCAT GTGTGTGGTG
    GCCTACTGCA AAACCAAGAA ACAGCGGAAA AAGCTGCATG ACCGTCTTCG GCAGAGCCTT
    CGGTCTGAAC GAAACAATAT GATGAACATT GCCAATGGGC CTCACCATCC TAACCCACCC
    CCCGAGAATG TCCAGCTGGT GAATCAATAC GTATCTAAAA ACGTCATCTC CAGTGAGCAT
    ATTGTTGAGA GAGAAGCAGA GACATCCTTT TCCACCAGTC ACTATACTTC CACAGCCCAT
    CACTCCACTA CTGTCACCCA GACTCCTAGC CACAGCTGGA GCAACGGACA CACTGAAAGC
    ATCCTTTCCG AAAGCCACTC TGTAATCGTG ATGTCATCCG TAGAAAACAG TAGGCACAGC
    AGCCCAACTG GGGGCCCAAG AGGACGTCTT AATGGCACAG GAGGCCCTCG TGAATGTAAC
    AGCTTCCTCA GGCATGCCAG AGAAACCCCT GATTCCTACC GAGACTCTCC TCATAGTGAA
    AGGTATGTGT CAGCCATGAC CACCCCGGCT CGTATGTCAC CTGTAGATTT CCACACGCCA
    AGCTCCCCCA AATCGCCCCC TTCGGAAATG TCTCCACCCG TGTCCAGCAT GACGGTGTCC
    ATGCCTTCCA TGGCGGTCAG CCCCTTCATG GAAGAAGAGA GACCTCTACT TCTCGTGACA
    CCACCAAGGC TGCGGGAGAA GAAGTTTGAC CATCACCCTC AGCAGTTCAG CTCCTTCCAC
    CACAACCCCG CGCATGACAG TAACAGCCTC CCTGCTAGCC CCTTGAGGAT AGTGGAGGAT
    GAGGAGTATG AAACGACCCA AGAGTACGAG CCAGCCCAAG AGCCTGTTAA GAAACTCGCC
    AATAGCCGGC GGGCCAAAAG AACCAAGCCC AATGGCCACA TTGCTAACAG ATTGGAAGTG
    GACAGCAACA CAAGCTCCCA GAGCAGTAAC TCAGAGAGTG AAACAGAAGA TGAAAGAGTA
    GGTGAAGATA CGCCTTTCCT GGGCATACAG AACCCCCTGG CAGCCAGTCT TGAGGCAACA
    CCTGCCTTCC GCCTGGCTGA CAGCAGGACT AACCCAGCAG GCCGCTTCTC GACACAGGAA
    GAAATCCAGG CCAGGCTGTC TAGTGTAATT GCTAACCAAG ACCCTATTGC TGTATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_016868856.1
    CDS92..1948
    Translation

    Target ORF information:

    RefSeq Version XM_017013367.1
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant X5, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_017013367.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    ATGGAGCCCG ACGCCAACAG CACCAGCCGC GCGCCGGCCG CCTTCCGAGC CTCTTTCCCC 
    CCTCTGGAGA CGGGCCGGAA CCTCAAGAAG GAGGTCAGCC GGGTGCTGTG CAAGCGGTGC
    GCCTTGCCTC CCCGATTGAA AGAGATGAAA AGCCAGGAAT CGGCTGCAGG TTCCAAACTA
    GTCCTTCGGT GTGAAACCAG TTCTGAATAC TCCTCTCTCA GATTCAAGTG GTTCAAGAAT
    GGGAATGAAT TGAATCGAAA AAACAAACCA CAAAATATCA AGATACAAAA AAAGCCAGGG
    AAGTCAGAAC TTCGCATTAA CAAAGCATCA CTGGCTGATT CTGGAGAGTA TATGTGCAAA
    GTGATCAGCA AATTAGGAAA TGACAGTGCC TCTGCCAATA TCACCATCGT GGAATCAAAC
    GCTACATCTA CATCCACCAC TGGGACAAGC CATCTTGTAA AATGTGCGGA GAAGGAGAAA
    ACTTTCTGTG TGAATGGAGG GGAGTGCTTC ATGGTGAAAG ACCTTTCAAA CCCCTCGAGA
    TACTTGTGCA AGTGCCCAAA TGAGTTTACT GGTGATCGCT GCCAAAACTA CGTAATGGCC
    AGCTTCTACA AGCATCTTGG GATTGAATTT ATGGAGGCGG AGGAGCTGTA CCAGAAGAGA
    GTGCTGACCA TAACCGGCAT CTGCATCGCC CTCCTTGTGG TCGGCATCAT GTGTGTGGTG
    GCCTACTGCA AAACCAAGAA ACAGCGGAAA AAGCTGCATG ACCGTCTTCG GCAGAGCCTT
    CGGTCTGAAC GAAACAATAT GATGAACATT GCCAATGGGC CTCACCATCC TAACCCACCC
    CCCGAGAATG TCCAGCTGGT GAATCAATAC GTATCTAAAA ACGTCATCTC CAGTGAGCAT
    ATTGTTGAGA GAGAAGCAGA GACATCCTTT TCCACCAGTC ACTATACTTC CACAGCCCAT
    CACTCCACTA CTGTCACCCA GACTCCTAGC CACAGCTGGA GCAACGGACA CACTGAAAGC
    ATCCTTTCCG AAAGCCACTC TGTAATCGTG ATGTCATCCG TAGAAAACAG TAGGCACAGC
    AGCCCAACTG GGGGCCCAAG AGGACGTCTT AATGGCACAG GAGGCCCTCG TGAATGTAAC
    AGCTTCCTCA GGCATGCCAG AGAAACCCCT GATTCCTACC GAGACTCTCC TCATAGTGAA
    AGGTATGTGT CAGCCATGAC CACCCCGGCT CGTATGTCAC CTGTAGATTT CCACACGCCA
    AGCTCCCCCA AATCGCCCCC TTCGGAAATG TCTCCACCCG TGTCCAGCAT GACGGTGTCC
    ATGCCTTCCA TGGCGGTCAG CCCCTTCATG GAAGAAGAGA GACCTCTACT TCTCGTGACA
    CCACCAAGGC TGCGGGAGAA GAAGTTTGAC CATCACCCTC AGCAGTTCAG CTCCTTCCAC
    CACAACCCCG CGCATGACAG TAACAGCCTC CCTGCTAGCC CCTTGAGGAT AGTGGAGGAT
    GAGGAGTATG AAACGACCCA AGAGTACGAG CCAGCCCAAG AGCCTGTTAA GAAACTCGCC
    AATAGCCGGC GGGCCAAAAG AACCAAGCCC AATGGCCACA TTGCTAACAG ATTGGAAGTG
    GACAGCAACA CAAGCTCCCA GAGCAGTAAC TCAGAGAGTG AAACAGAAGA TGAAAGAGTA
    GGTGAAGATA CGCCTTTCCT GGGCATACAG AACCCCCTGG CAGCCAGTCT TGAGGCAACA
    CCTGCCTTCC GCCTGGCTGA CAGCAGGACT AACCCAGCAG GCCGCTTCTC GACACAGGAA
    GAAATCCAGG CCAGGCTGTC TAGTGTAATT GCTAACCAAG ACCCTATTGC TGTATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu97936
    Clone ID Related Accession (Same CDS sequence) XM_017013368.1 , XM_017013368.2
    Accession Version XM_017013368.1 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1836bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2016-06-05
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform X6
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG CTACATCTAC ATCCACCACT
    GGGACAAGCC ATCTTGTAAA ATGTGCGGAG AAGGAGAAAA CTTTCTGTGT GAATGGAGGG
    GAGTGCTTCA TGGTGAAAGA CCTTTCAAAC CCCTCGAGAT ACTTGTGCAA GTGCCCAAAT
    GAGTTTACTG GTGATCGCTG CCAAAACTAC GTAATGGCCA GCTTCTACAA GCATCTTGGG
    ATTGAATTTA TGGAGGCGGA GGAGCTGTAC CAGAAGAGAG TGCTGACCAT AACCGGCATC
    TGCATCGCCC TCCTTGTGGT CGGCATCATG TGTGTGGTGG CCTACTGCAA AACCAAGAAA
    CAGCGGAAAA AGCTGCATGA CCGTCTTCGG CAGAGCCTTC GGTCTGAACG AAACAATATG
    ATGAACATTG CCAATGGGCC TCACCATCCT AACCCACCCC CCGAGAATGT CCAGCTGGTG
    AATCAATACG TATCTAAAAA CGTCATCTCC AGTGAGCATA TTGTTGAGAG AGAAGCAGAG
    ACATCCTTTT CCACCAGTCA CTATACTTCC ACAGCCCATC ACTCCACTAC TGTCACCCAG
    ACTCCTAGCC ACAGCTGGAG CAACGGACAC ACTGAAAGCA TCCTTTCCGA AAGCCACTCT
    GTAATCGTGA TGTCATCCGT AGAAAACAGT AGGCACAGCA GCCCAACTGG GGGCCCAAGA
    GGACGTCTTA ATGGCACAGG AGGCCCTCGT GAATGTAACA GCTTCCTCAG GCATGCCAGA
    GAAACCCCTG ATTCCTACCG AGACTCTCCT CATAGTGAAA GGTATGTGTC AGCCATGACC
    ACCCCGGCTC GTATGTCACC TGTAGATTTC CACACGCCAA GCTCCCCCAA ATCGCCCCCT
    TCGGAAATGT CTCCACCCGT GTCCAGCATG ACGGTGTCCA TGCCTTCCAT GGCGGTCAGC
    CCCTTCATGG AAGAAGAGAG ACCTCTACTT CTCGTGACAC CACCAAGGCT GCGGGAGAAG
    AAGTTTGACC ATCACCCTCA GCAGTTCAGC TCCTTCCACC ACAACCCCGC GCATGACAGT
    AACAGCCTCC CTGCTAGCCC CTTGAGGATA GTGGAGGATG AGGAGTATGA AACGACCCAA
    GAGTACGAGC CAGCCCAAGA GCCTGTTAAG AAACTCGCCA ATAGCCGGCG GGCCAAAAGA
    ACCAAGCCCA ATGGCCACAT TGCTAACAGA TTGGAAGTGG ACAGCAACAC AAGCTCCCAG
    AGCAGTAACT CAGAGAGTGA AACAGAAGAT GAAAGAGTAG GTGAAGATAC GCCTTTCCTG
    GGCATACAGA ACCCCCTGGC AGCCAGTCTT GAGGCAACAC CTGCCTTCCG CCTGGCTGAC
    AGCAGGACTA ACCCAGCAGG CCGCTTCTCG ACACAGGAAG AAATCCAGGC CAGGCTGTCT
    AGTGTAATTG CTAACCAAGA CCCTATTGCT GTATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_016868857.1
    CDS450..2285
    Translation

    Target ORF information:

    RefSeq Version XM_017013368.1
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant X6, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_017013368.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG CTACATCTAC ATCCACCACT
    GGGACAAGCC ATCTTGTAAA ATGTGCGGAG AAGGAGAAAA CTTTCTGTGT GAATGGAGGG
    GAGTGCTTCA TGGTGAAAGA CCTTTCAAAC CCCTCGAGAT ACTTGTGCAA GTGCCCAAAT
    GAGTTTACTG GTGATCGCTG CCAAAACTAC GTAATGGCCA GCTTCTACAA GCATCTTGGG
    ATTGAATTTA TGGAGGCGGA GGAGCTGTAC CAGAAGAGAG TGCTGACCAT AACCGGCATC
    TGCATCGCCC TCCTTGTGGT CGGCATCATG TGTGTGGTGG CCTACTGCAA AACCAAGAAA
    CAGCGGAAAA AGCTGCATGA CCGTCTTCGG CAGAGCCTTC GGTCTGAACG AAACAATATG
    ATGAACATTG CCAATGGGCC TCACCATCCT AACCCACCCC CCGAGAATGT CCAGCTGGTG
    AATCAATACG TATCTAAAAA CGTCATCTCC AGTGAGCATA TTGTTGAGAG AGAAGCAGAG
    ACATCCTTTT CCACCAGTCA CTATACTTCC ACAGCCCATC ACTCCACTAC TGTCACCCAG
    ACTCCTAGCC ACAGCTGGAG CAACGGACAC ACTGAAAGCA TCCTTTCCGA AAGCCACTCT
    GTAATCGTGA TGTCATCCGT AGAAAACAGT AGGCACAGCA GCCCAACTGG GGGCCCAAGA
    GGACGTCTTA ATGGCACAGG AGGCCCTCGT GAATGTAACA GCTTCCTCAG GCATGCCAGA
    GAAACCCCTG ATTCCTACCG AGACTCTCCT CATAGTGAAA GGTATGTGTC AGCCATGACC
    ACCCCGGCTC GTATGTCACC TGTAGATTTC CACACGCCAA GCTCCCCCAA ATCGCCCCCT
    TCGGAAATGT CTCCACCCGT GTCCAGCATG ACGGTGTCCA TGCCTTCCAT GGCGGTCAGC
    CCCTTCATGG AAGAAGAGAG ACCTCTACTT CTCGTGACAC CACCAAGGCT GCGGGAGAAG
    AAGTTTGACC ATCACCCTCA GCAGTTCAGC TCCTTCCACC ACAACCCCGC GCATGACAGT
    AACAGCCTCC CTGCTAGCCC CTTGAGGATA GTGGAGGATG AGGAGTATGA AACGACCCAA
    GAGTACGAGC CAGCCCAAGA GCCTGTTAAG AAACTCGCCA ATAGCCGGCG GGCCAAAAGA
    ACCAAGCCCA ATGGCCACAT TGCTAACAGA TTGGAAGTGG ACAGCAACAC AAGCTCCCAG
    AGCAGTAACT CAGAGAGTGA AACAGAAGAT GAAAGAGTAG GTGAAGATAC GCCTTTCCTG
    GGCATACAGA ACCCCCTGGC AGCCAGTCTT GAGGCAACAC CTGCCTTCCG CCTGGCTGAC
    AGCAGGACTA ACCCAGCAGG CCGCTTCTCG ACACAGGAAG AAATCCAGGC CAGGCTGTCT
    AGTGTAATTG CTAACCAAGA CCCTATTGCT GTATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu97936
    Clone ID Related Accession (Same CDS sequence) XM_017013368.1 , XM_017013368.2
    Accession Version XM_017013368.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1836bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-05
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform X6
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017013368.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG CTACATCTAC ATCCACCACT
    GGGACAAGCC ATCTTGTAAA ATGTGCGGAG AAGGAGAAAA CTTTCTGTGT GAATGGAGGG
    GAGTGCTTCA TGGTGAAAGA CCTTTCAAAC CCCTCGAGAT ACTTGTGCAA GTGCCCAAAT
    GAGTTTACTG GTGATCGCTG CCAAAACTAC GTAATGGCCA GCTTCTACAA GCATCTTGGG
    ATTGAATTTA TGGAGGCGGA GGAGCTGTAC CAGAAGAGAG TGCTGACCAT AACCGGCATC
    TGCATCGCCC TCCTTGTGGT CGGCATCATG TGTGTGGTGG CCTACTGCAA AACCAAGAAA
    CAGCGGAAAA AGCTGCATGA CCGTCTTCGG CAGAGCCTTC GGTCTGAACG AAACAATATG
    ATGAACATTG CCAATGGGCC TCACCATCCT AACCCACCCC CCGAGAATGT CCAGCTGGTG
    AATCAATACG TATCTAAAAA CGTCATCTCC AGTGAGCATA TTGTTGAGAG AGAAGCAGAG
    ACATCCTTTT CCACCAGTCA CTATACTTCC ACAGCCCATC ACTCCACTAC TGTCACCCAG
    ACTCCTAGCC ACAGCTGGAG CAACGGACAC ACTGAAAGCA TCCTTTCCGA AAGCCACTCT
    GTAATCGTGA TGTCATCCGT AGAAAACAGT AGGCACAGCA GCCCAACTGG GGGCCCAAGA
    GGACGTCTTA ATGGCACAGG AGGCCCTCGT GAATGTAACA GCTTCCTCAG GCATGCCAGA
    GAAACCCCTG ATTCCTACCG AGACTCTCCT CATAGTGAAA GGTATGTGTC AGCCATGACC
    ACCCCGGCTC GTATGTCACC TGTAGATTTC CACACGCCAA GCTCCCCCAA ATCGCCCCCT
    TCGGAAATGT CTCCACCCGT GTCCAGCATG ACGGTGTCCA TGCCTTCCAT GGCGGTCAGC
    CCCTTCATGG AAGAAGAGAG ACCTCTACTT CTCGTGACAC CACCAAGGCT GCGGGAGAAG
    AAGTTTGACC ATCACCCTCA GCAGTTCAGC TCCTTCCACC ACAACCCCGC GCATGACAGT
    AACAGCCTCC CTGCTAGCCC CTTGAGGATA GTGGAGGATG AGGAGTATGA AACGACCCAA
    GAGTACGAGC CAGCCCAAGA GCCTGTTAAG AAACTCGCCA ATAGCCGGCG GGCCAAAAGA
    ACCAAGCCCA ATGGCCACAT TGCTAACAGA TTGGAAGTGG ACAGCAACAC AAGCTCCCAG
    AGCAGTAACT CAGAGAGTGA AACAGAAGAT GAAAGAGTAG GTGAAGATAC GCCTTTCCTG
    GGCATACAGA ACCCCCTGGC AGCCAGTCTT GAGGCAACAC CTGCCTTCCG CCTGGCTGAC
    AGCAGGACTA ACCCAGCAGG CCGCTTCTCG ACACAGGAAG AAATCCAGGC CAGGCTGTCT
    AGTGTAATTG CTAACCAAGA CCCTATTGCT GTATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_016868857.1
    CDS518..2353
    Translation

    Target ORF information:

    RefSeq Version XM_017013368.2
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant X6, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_017013368.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    ATGTCCGAGC GCAAAGAAGG CAGAGGCAAA GGGAAGGGCA AGAAGAAGGA GCGAGGCTCC 
    GGCAAGAAGC CGGAGTCCGC GGCGGGCAGC CAGAGCCCAG CCTTGCCTCC CCGATTGAAA
    GAGATGAAAA GCCAGGAATC GGCTGCAGGT TCCAAACTAG TCCTTCGGTG TGAAACCAGT
    TCTGAATACT CCTCTCTCAG ATTCAAGTGG TTCAAGAATG GGAATGAATT GAATCGAAAA
    AACAAACCAC AAAATATCAA GATACAAAAA AAGCCAGGGA AGTCAGAACT TCGCATTAAC
    AAAGCATCAC TGGCTGATTC TGGAGAGTAT ATGTGCAAAG TGATCAGCAA ATTAGGAAAT
    GACAGTGCCT CTGCCAATAT CACCATCGTG GAATCAAACG CTACATCTAC ATCCACCACT
    GGGACAAGCC ATCTTGTAAA ATGTGCGGAG AAGGAGAAAA CTTTCTGTGT GAATGGAGGG
    GAGTGCTTCA TGGTGAAAGA CCTTTCAAAC CCCTCGAGAT ACTTGTGCAA GTGCCCAAAT
    GAGTTTACTG GTGATCGCTG CCAAAACTAC GTAATGGCCA GCTTCTACAA GCATCTTGGG
    ATTGAATTTA TGGAGGCGGA GGAGCTGTAC CAGAAGAGAG TGCTGACCAT AACCGGCATC
    TGCATCGCCC TCCTTGTGGT CGGCATCATG TGTGTGGTGG CCTACTGCAA AACCAAGAAA
    CAGCGGAAAA AGCTGCATGA CCGTCTTCGG CAGAGCCTTC GGTCTGAACG AAACAATATG
    ATGAACATTG CCAATGGGCC TCACCATCCT AACCCACCCC CCGAGAATGT CCAGCTGGTG
    AATCAATACG TATCTAAAAA CGTCATCTCC AGTGAGCATA TTGTTGAGAG AGAAGCAGAG
    ACATCCTTTT CCACCAGTCA CTATACTTCC ACAGCCCATC ACTCCACTAC TGTCACCCAG
    ACTCCTAGCC ACAGCTGGAG CAACGGACAC ACTGAAAGCA TCCTTTCCGA AAGCCACTCT
    GTAATCGTGA TGTCATCCGT AGAAAACAGT AGGCACAGCA GCCCAACTGG GGGCCCAAGA
    GGACGTCTTA ATGGCACAGG AGGCCCTCGT GAATGTAACA GCTTCCTCAG GCATGCCAGA
    GAAACCCCTG ATTCCTACCG AGACTCTCCT CATAGTGAAA GGTATGTGTC AGCCATGACC
    ACCCCGGCTC GTATGTCACC TGTAGATTTC CACACGCCAA GCTCCCCCAA ATCGCCCCCT
    TCGGAAATGT CTCCACCCGT GTCCAGCATG ACGGTGTCCA TGCCTTCCAT GGCGGTCAGC
    CCCTTCATGG AAGAAGAGAG ACCTCTACTT CTCGTGACAC CACCAAGGCT GCGGGAGAAG
    AAGTTTGACC ATCACCCTCA GCAGTTCAGC TCCTTCCACC ACAACCCCGC GCATGACAGT
    AACAGCCTCC CTGCTAGCCC CTTGAGGATA GTGGAGGATG AGGAGTATGA AACGACCCAA
    GAGTACGAGC CAGCCCAAGA GCCTGTTAAG AAACTCGCCA ATAGCCGGCG GGCCAAAAGA
    ACCAAGCCCA ATGGCCACAT TGCTAACAGA TTGGAAGTGG ACAGCAACAC AAGCTCCCAG
    AGCAGTAACT CAGAGAGTGA AACAGAAGAT GAAAGAGTAG GTGAAGATAC GCCTTTCCTG
    GGCATACAGA ACCCCCTGGC AGCCAGTCTT GAGGCAACAC CTGCCTTCCG CCTGGCTGAC
    AGCAGGACTA ACCCAGCAGG CCGCTTCTCG ACACAGGAAG AAATCCAGGC CAGGCTGTCT
    AGTGTAATTG CTAACCAAGA CCCTATTGCT GTATAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu28449
    Clone ID Related Accession (Same CDS sequence) NM_013962.2
    Accession Version NM_013962.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1269bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-20
    Organism Homo sapiens(human)
    Product pro-neuregulin-1, membrane-bound isoform isoform GGF2 precursor
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from L12260.1, M94165.1 and M94168.1. This sequence is a reference standard in the RefSeqGene project. On Oct 10, 2006 this sequence version replaced NM_013962.1. Transcript Variant: This variant (GGF2), which uses the type II promoter, is expressed in the nervous system and functions as a neuronal signal that promotes the proliferation and survival of the oligodendrocyte and the myelinating cell. This variant contains alternate 5' and 3' terminal exons and thus differs in the 5' and 3' coding regions and in both UTRs, and it also lacks two alternate in-frame exons in the central coding region, compared to variant HRG-beta1. The resulting isoform (GGF2, also known as GGFHBS5) has distinct N- and C-termini, lacks an internal segment, and is shorter than isoform HRG-beta1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: L12260.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2154665, SAMN03465403 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGAGATGGC GACGCGCCCC GCGCCGCTCC GGGCGTCCCG GCCCCCGGGC CCAGCGCCCC 
    GGCTCCGCCG CCCGCTCGTC GCCGCCGCTG CCGCTGCTGC CACTACTGCT GCTGCTGGGG
    ACCGCGGCCC TGGCGCCGGG GGCGGCGGCC GGCAACGAGG CGGCTCCCGC GGGGGCCTCG
    GTGTGCTACT CGTCCCCGCC CAGCGTGGGA TCGGTGCAGG AGCTAGCTCA GCGCGCCGCG
    GTGGTGATCG AGGGAAAGGT GCACCCGCAG CGGCGGCAGC AGGGGGCACT CGACAGGAAG
    GCGGCGGCGG CGGCGGGCGA GGCAGGGGCG TGGGGCGGCG ATCGCGAGCC GCCAGCCGCG
    GGCCCACGGG CGCTGGGGCC GCCCGCCGAG GAGCCGCTGC TCGCCGCCAA CGGGACCGTG
    CCCTCTTGGC CCACCGCCCC GGTGCCCAGC GCCGGCGAGC CCGGGGAGGA GGCGCCCTAT
    CTGGTGAAGG TGCACCAGGT GTGGGCGGTG AAAGCCGGGG GCTTGAAGAA GGACTCGCTG
    CTCACCGTGC GCCTGGGGAC CTGGGGCCAC CCCGCCTTCC CCTCCTGCGG GAGGCTCAAG
    GAGGACAGCA GGTACATCTT CTTCATGGAG CCCGACGCCA ACAGCACCAG CCGCGCGCCG
    GCCGCCTTCC GAGCCTCTTT CCCCCCTCTG GAGACGGGCC GGAACCTCAA GAAGGAGGTC
    AGCCGGGTGC TGTGCAAGCG GTGCGCCTTG CCTCCCCGAT TGAAAGAGAT GAAAAGCCAG
    GAATCGGCTG CAGGTTCCAA ACTAGTCCTT CGGTGTGAAA CCAGTTCTGA ATACTCCTCT
    CTCAGATTCA AGTGGTTCAA GAATGGGAAT GAATTGAATC GAAAAAACAA ACCACAAAAT
    ATCAAGATAC AAAAAAAGCC AGGGAAGTCA GAACTTCGCA TTAACAAAGC ATCACTGGCT
    GATTCTGGAG AGTATATGTG CAAAGTGATC AGCAAATTAG GAAATGACAG TGCCTCTGCC
    AATATCACCA TCGTGGAATC AAACGCTACA TCTACATCCA CCACTGGGAC AAGCCATCTT
    GTAAAATGTG CGGAGAAGGA GAAAACTTTC TGTGTGAATG GAGGGGAGTG CTTCATGGTG
    AAAGACCTTT CAAACCCCTC GAGATACTTG TGCAAGTGCC CAAATGAGTT TACTGGTGAT
    CGCTGCCAAA ACTACGTAAT GGCCAGCTTC TACAGTACGT CCACTCCCTT TCTGTCTCTG
    CCTGAATAG

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_039256.2
    CDS234..1502
    Translation

    Target ORF information:

    RefSeq Version NM_013962.2
    Organism Homo sapiens(human)
    Definition Homo sapiens neuregulin 1 (NRG1), transcript variant GGF2, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_013962.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGAGATGGC GACGCGCCCC GCGCCGCTCC GGGCGTCCCG GCCCCCGGGC CCAGCGCCCC 
    GGCTCCGCCG CCCGCTCGTC GCCGCCGCTG CCGCTGCTGC CACTACTGCT GCTGCTGGGG
    ACCGCGGCCC TGGCGCCGGG GGCGGCGGCC GGCAACGAGG CGGCTCCCGC GGGGGCCTCG
    GTGTGCTACT CGTCCCCGCC CAGCGTGGGA TCGGTGCAGG AGCTAGCTCA GCGCGCCGCG
    GTGGTGATCG AGGGAAAGGT GCACCCGCAG CGGCGGCAGC AGGGGGCACT CGACAGGAAG
    GCGGCGGCGG CGGCGGGCGA GGCAGGGGCG TGGGGCGGCG ATCGCGAGCC GCCAGCCGCG
    GGCCCACGGG CGCTGGGGCC GCCCGCCGAG GAGCCGCTGC TCGCCGCCAA CGGGACCGTG
    CCCTCTTGGC CCACCGCCCC GGTGCCCAGC GCCGGCGAGC CCGGGGAGGA GGCGCCCTAT
    CTGGTGAAGG TGCACCAGGT GTGGGCGGTG AAAGCCGGGG GCTTGAAGAA GGACTCGCTG
    CTCACCGTGC GCCTGGGGAC CTGGGGCCAC CCCGCCTTCC CCTCCTGCGG GAGGCTCAAG
    GAGGACAGCA GGTACATCTT CTTCATGGAG CCCGACGCCA ACAGCACCAG CCGCGCGCCG
    GCCGCCTTCC GAGCCTCTTT CCCCCCTCTG GAGACGGGCC GGAACCTCAA GAAGGAGGTC
    AGCCGGGTGC TGTGCAAGCG GTGCGCCTTG CCTCCCCGAT TGAAAGAGAT GAAAAGCCAG
    GAATCGGCTG CAGGTTCCAA ACTAGTCCTT CGGTGTGAAA CCAGTTCTGA ATACTCCTCT
    CTCAGATTCA AGTGGTTCAA GAATGGGAAT GAATTGAATC GAAAAAACAA ACCACAAAAT
    ATCAAGATAC AAAAAAAGCC AGGGAAGTCA GAACTTCGCA TTAACAAAGC ATCACTGGCT
    GATTCTGGAG AGTATATGTG CAAAGTGATC AGCAAATTAG GAAATGACAG TGCCTCTGCC
    AATATCACCA TCGTGGAATC AAACGCTACA TCTACATCCA CCACTGGGAC AAGCCATCTT
    GTAAAATGTG CGGAGAAGGA GAAAACTTTC TGTGTGAATG GAGGGGAGTG CTTCATGGTG
    AAAGACCTTT CAAACCCCTC GAGATACTTG TGCAAGTGCC CAAATGAGTT TACTGGTGAT
    CGCTGCCAAA ACTACGTAAT GGCCAGCTTC TACAGTACGT CCACTCCCTT TCTGTCTCTG
    CCTGAATAG

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.