GRB14 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	GRB14
Entrez Gene ID	2888
Full Name	growth factor receptor bound protein 14
General protein information	Preferred Names growth factor receptor bound protein 14 Names growth factor receptor-bound protein 14 GRB14 adapter protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2q24.3
Summary	The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. This protein likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. This gene may play a role in signaling pathways that regulate growth and metabolism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014].
Disorder MIM:	601524

mRNA and Protein(s)

mRNA	Protein	Name
NM_004490.3	NP_004481.2	growth factor receptor-bound protein 14 isoform 1
XM_024452815.1	XP_024308583.1	growth factor receptor-bound protein 14 isoform X1
XM_011511022.2	XP_011509324.1	growth factor receptor-bound protein 14 isoform X3
NM_004490.2	NP_004481.2	growth factor receptor-bound protein 14 isoform 1
NM_001303422.1	NP_001290351.1	growth factor receptor-bound protein 14 isoform 2
NM_001303422.2	NP_001290351.1	growth factor receptor-bound protein 14 isoform 2
XM_024452816.1	XP_024308584.1	growth factor receptor-bound protein 14 isoform X1
XM_017003899.1	XP_016859388.1	growth factor receptor-bound protein 14 isoform X2

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Grb14	NP_113811.1
Danio rerio (zebrafish)	LOC100334415	XP_002661994.2
Xenopus tropicalis (tropical clawed frog)	grb14	XP_004917759.1
Bos taurus (cattle)	GRB14	NP_001011681.2
Gallus gallus (chicken)	GRB14	XP_422029.4
Homo sapiens (human)	GRB14	NP_004481.2
Pan troglodytes (chimpanzee)	GRB14	XP_515864.2
Mus musculus (house mouse)	Grb14	NP_057928.1
	LOC707075	XP_002808050.1
Canis lupus familiaris (dog)	GRB14	XP_005640314.1

Gene Ontology
Bibliography

Related articles in PubMed

Phosphorylation of clustered serine residues in the N-terminus of BPS domain negatively regulates formation of the complex between human Grb14 and insulin receptor.
Taira J, Kida Y, Inatomi K, Komatsu H, Higashimoto Y, Sakamoto H
Journal of biochemistry162(2)113-122(2017 Aug)

The adaptors Grb10 and Grb14 are calmodulin-binding proteins.
Garc?a-Palmero I, Pompas-Veganzones N, Villalobo E, Gioria S, Haiech J, Villalobo A
FEBS letters591(8)1176-1186(2017 04)

Air pollution and diabetes association: Modification by type 2 diabetes genetic risk score.
Eze IC, Imboden M, Kumar A, von Eckardstein A, Stolz D, Gerbase MW, K?nzli N, Pons M, Kronenberg F, Schindler C, Probst-Hensch N
Environment international94263-271(2016 Sep)

High expression of growth factor receptor-bound protein 14 predicts poor prognosis for colorectal cancer patients.
Yang P, Wei J, Li W, He F, Zeng S, Zhang T, Sun Z, Cao J
Biotechnology letters38(6)1043-7(2016 Jun)

Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia.
Simino J, Shi G, Bis JC, Chasman DI, Ehret GB, Gu X, Guo X, Hwang SJ, Sijbrands E, Smith AV, Verwoert GC, Bragg-Gresham JL, Cadby G, Chen P, Cheng CY, Corre T, de Boer RA, Goel A, Johnson T, Khor CC, , Llu?s-Ganella C, Luan J, Lyytik?inen LP, Nolte IM, Sim X, S?ber S, van der Most PJ, Verweij N, Zhao JH, Amin N, Boerwinkle E, Bouchard C, Dehghan A, Eiriksdottir G, Elosua R, Franco OH, Gieger C, Harris TB, Hercberg S, Hofman A, James AL, Johnson AD, K?h?nen M, Khaw KT, Kutalik Z, Larson MG, Launer LJ, Li G, Liu J, Liu K, Morrison AC, Navis G, Ong RT, Papanicolau GJ, Penninx BW, Psaty BM, Raffel LJ, Raitakari OT, Rice K, Rivadeneira F, Rose LM, Sanna S, Scott RA, Siscovick DS, Stolk RP, Uitterlinden AG, Vaidya D, van der Klauw MM, Vasan RS, Vithana EN, V?lker U, V?lzke H, Watkins H, Young TL, Aung T, Bochud M, Farrall M, Hartman CA, Laan M, Lakatta EG, Lehtim?ki T, Loos RJ, Lucas G, Meneton P, Palmer LJ, Rettig R, Snieder H, Tai ES, Teo YY, van der Harst P, Wareham NJ, Wijmenga C, Wong TY, Fornage M, Gudnason V, Levy D, Palmas W, Ridker PM, Rotter JI, van Duijn CM, Witteman JC, Chakravarti A, Rao DC
American journal of human genetics95(1)24-38(2014 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The N-terminus of the BPS domain plays an important role in the regulation of human Grb14 and insulin receptor complex formation through phosphorylation, in addition to other domains.
Title: Phosphorylation of clustered serine residues in the N-terminus of BPS domain negatively regulates formation of the complex between human Grb14 and insulin receptor.

Data suggest that GRB10 and GRB14 are both Ca2+-dependent CaM-binding proteins; more than one CaM-binding site and/or accessory CaM-binding sites appear to exist in GRB10 and GRB14, as compared to a single one present in GRB7. (GRB10 = growth factor receptor-bound protein 10; GRB14 = growth factor receptor-bound protein 14; CaM = calmodulin; GRB7 = growth factor receptor-bound protein 7)
Title: The adaptors Grb10 and Grb14 are calmodulin-binding proteins.

Colorectal cancer patients with high GRB14 levels had a shorter survival and GRB14 was upregulated at an advanced clinical stage with enhanced tumor invasion and lymph node metastasis.
Title: High expression of growth factor receptor-bound protein 14 predicts poor prognosis for colorectal cancer patients.

Phosphorylation of Grb14 BPS domain by GSK-3 correlates with complex forming of Grb14 and insulin receptor.
Title: Phosphorylation of Grb14 BPS domain by GSK-3 correlates with complex forming of Grb14 and insulin receptor.

Modulation of mouse rod photoreceptor responses by Grb14 protein.
Title: Modulation of mouse rod photoreceptor responses by Grb14 protein.

The following GRB14 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GRB14 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu36146	XM_017003899.1 Latest version!	Homo sapiens growth factor receptor bound protein 14 (GRB14), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
OHu13500	NM_004490.3 Latest version!	Homo sapiens growth factor receptor bound protein 14 (GRB14), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu36145	NM_001303422.2 Latest version!	Homo sapiens growth factor receptor bound protein 14 (GRB14), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu58055	XM_011511022.2 Latest version!	Homo sapiens growth factor receptor bound protein 14 (GRB14), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu104860	XM_024452815.1 Latest version!	Homo sapiens growth factor receptor bound protein 14 (GRB14), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu104860	XM_024452816.1 Latest version!	Homo sapiens growth factor receptor bound protein 14 (GRB14), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OHu13500	NM_004490.2	Homo sapiens growth factor receptor bound protein 14 (GRB14), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu36145	NM_001303422.1	Homo sapiens growth factor receptor bound protein 14 (GRB14), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GRB14 ( XM_017003899.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016859388.1 Homo sapiens growth factor receptor bound protein 14 (GRB14), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu36146
Clone ID Related Accession (Same CDS sequence)	XM_017003899.1
Accession Version	XM_017003899.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1023bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	growth factor receptor-bound protein 14 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTATTTTT TTCCAGAGCA TATGGTATCT TTTGCAACTG AAACCAATGG TGAAATATCC 
CCCACACAGA TTTTGCAGAT GTTTCTGAGT TCAAGCACAT ATCCTGAAAT TCATGGTTTC 
TTACATGCGA AAGAACAGGG AAAGAAGTCT TGGAAAAAAA TTTACTTTTT TCTAAGAAGA 
TCTGGTTTAT ATTTTTCTAC TAAAGGAACA TCAAAGGAAC CGCGGCATTT GCAGTTTTTC 
AGCGAATTTG GCAATAGTGA TATTTATGTG TCACTGGCAG GCAAAAAAAA ACATGGAGCA 
CCGACTAACT ATGGATTCTG CTTTAAGCCT AACAAAGCGG GAGGGCCCCG AGACCTGAAA 
ATGCTCTGTG CAGAAGAAGA GCAGAGTAGG ACGTGCTGGG TGACCGCGAT TAGATTGCTT 
AAGTATGGCA TGCAGCTGTA CCAGAATTAT ATGCATCCAT ATCAAGGTAG AAGTGGCTGC 
AGTTCACAGA GCATATCACC TATGAGAAGT ATATCAGAGA ATTCCCTGGT AGCAATGGAC 
TTCTCAGGCC AGAAAAGCAG AGTTATAGAA AATCCCACTG AAGCCCTTTC AGTTGCGGTT 
GAAGAAGGAC TCGCTTGGAG GAAAAAAGGA TGTTTACGCC TGGGCACTCA CGGTAGCCCC 
ACTGCCTCTT CACAGAGCTC TGCCACAAAC ATGGCTATCC ACCGGTCCCA GCCATGGTTT 
CACCACAAAA TTTCTAGAGA TGAGGCTCAG CGATTGATTA TTCAGCAAGG ACTTGTGGAT 
GGAGTTTTCT TGGTACGGGA TAGTCAGAGT AACCCCAAAA CTTTCGTACT GTCAATGAGT 
CATGGACAAA AAATAAAGCA CTTTCAAATT ATACCAGTAG AAGATGACGG TGAAATGTTC 
CACACACTGG ATGATGGCCA CACAAGATTT ACAGATCTAA TACAGCTGGT GGAGTTCTAT 
CAACTCAATA AGGGCGTTCT TCCTTGCAAG TTGAAACATT ATTGTGCTAG GATTGCTCTC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016859388.1
CDS	579..1601
Translation	MYFFPEHMVSFATETNGEISPTQILQMFLSSSTYPEIHGFLHAKEQGKKSWKKIYFFLRRSGLYFSTKGTSKEPRHLQFFSEFGNSDIYVSLAGKKKHGAPTNYGFCFKPNKAGGPRDLKMLCAEEEQSRTCWVTAIRLLKYGMQLYQNYMHPYQGRSGCSSQSISPMRSISENSLVAMDFSGQKSRVIENPTEALSVAVEEGLAWRKKGCLRLGTHGSPTASSQSSATNMAIHRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNPKTFVLSMSHGQKIKHFQIIPVEDDGEMFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCKLKHYCARIAL

Target ORF information:

RefSeq Version	XM_017003899.1
Organism	Homo sapiens(human)
Definition	Homo sapiens growth factor receptor bound protein 14 (GRB14), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017003899.1

ORF Insert Sequence:

ATGTATTTTT TTCCAGAGCA TATGGTATCT TTTGCAACTG AAACCAATGG TGAAATATCC 
CCCACACAGA TTTTGCAGAT GTTTCTGAGT TCAAGCACAT ATCCTGAAAT TCATGGTTTC 
TTACATGCGA AAGAACAGGG AAAGAAGTCT TGGAAAAAAA TTTACTTTTT TCTAAGAAGA 
TCTGGTTTAT ATTTTTCTAC TAAAGGAACA TCAAAGGAAC CGCGGCATTT GCAGTTTTTC 
AGCGAATTTG GCAATAGTGA TATTTATGTG TCACTGGCAG GCAAAAAAAA ACATGGAGCA 
CCGACTAACT ATGGATTCTG CTTTAAGCCT AACAAAGCGG GAGGGCCCCG AGACCTGAAA 
ATGCTCTGTG CAGAAGAAGA GCAGAGTAGG ACGTGCTGGG TGACCGCGAT TAGATTGCTT 
AAGTATGGCA TGCAGCTGTA CCAGAATTAT ATGCATCCAT ATCAAGGTAG AAGTGGCTGC 
AGTTCACAGA GCATATCACC TATGAGAAGT ATATCAGAGA ATTCCCTGGT AGCAATGGAC 
TTCTCAGGCC AGAAAAGCAG AGTTATAGAA AATCCCACTG AAGCCCTTTC AGTTGCGGTT 
GAAGAAGGAC TCGCTTGGAG GAAAAAAGGA TGTTTACGCC TGGGCACTCA CGGTAGCCCC 
ACTGCCTCTT CACAGAGCTC TGCCACAAAC ATGGCTATCC ACCGGTCCCA GCCATGGTTT 
CACCACAAAA TTTCTAGAGA TGAGGCTCAG CGATTGATTA TTCAGCAAGG ACTTGTGGAT 
GGAGTTTTCT TGGTACGGGA TAGTCAGAGT AACCCCAAAA CTTTCGTACT GTCAATGAGT 
CATGGACAAA AAATAAAGCA CTTTCAAATT ATACCAGTAG AAGATGACGG TGAAATGTTC 
CACACACTGG ATGATGGCCA CACAAGATTT ACAGATCTAA TACAGCTGGT GGAGTTCTAT 
CAACTCAATA AGGGCGTTCT TCCTTGCAAG TTGAAACATT ATTGTGCTAG GATTGCTCTC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GRB14 ( NM_004490.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_004481.2 Homo sapiens growth factor receptor bound protein 14 (GRB14), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu13500
Clone ID Related Accession (Same CDS sequence)	NM_004490.3 , NM_004490.2
Accession Version	NM_004490.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1623bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-24
Organism	Homo sapiens(human)
Product	growth factor receptor-bound protein 14 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC107075.4, BC053559.1 and AC110086.3. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_004490.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.267463.1, SRR1803612.265908.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968189, SAMEA1968540 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000263915.8/ ENSP00000263915.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGACCACTT CCCTGCAAGA TGGGCAGAGC GCCGCGAGCA GGGCGGCTGC CCGGGATTCG 
CCGCTGGCCG CCCAGGTGTG TGGCGCTGCC CAGGGGAGGG GCGACGCCCA CGACCTGGCG 
CCGGCCCCCT GGCTGCACGC GCGAGCGCTC CTGCCCCTTC CGGACGGGAC CCGCGGCTGT 
GCTGCAGACA GGAGAAAAAA GAAAGATCTT GATGTTCCGG AAATGCCATC TATTCCAAAC 
CCTTTTCCTG AGCTATGCTG TTCTCCATTT ACATCTGTGT TGTCAGCAGA CCTATTTCCC 
AAAGCAAATT CAAGGAAAAA ACAGGTGATT AAAGTATACA GTGAAGATGA AACCAGCAGG 
GCTTTAGATG TACCCAGTGA CATAACGGCT CGAGATGTTT GTCAGCTGTT GATCCTGAAG 
AATCATTACA TTGATGACCA CAGCTGGACC CTTTTTGAGC ACCTGCCTCA CATAGGTGTA 
GAAAGAACAA TAGAAGACCA CGAACTGGTG ATTGAAGTGC TATCCAACTG GGGGATAGAA 
GAAGAAAACA AACTATACTT TAGAAAAAAT TATGCCAAAT ATGAGTTCTT TAAAAACCCA 
ATGTATTTTT TTCCAGAGCA TATGGTATCT TTTGCAACTG AAACCAATGG TGAAATATCC 
CCCACACAGA TTTTGCAGAT GTTTCTGAGT TCAAGCACAT ATCCTGAAAT TCATGGTTTC 
TTACATGCGA AAGAACAGGG AAAGAAGTCT TGGAAAAAAA TTTACTTTTT TCTAAGAAGA 
TCTGGTTTAT ATTTTTCTAC TAAAGGAACA TCAAAGGAAC CGCGGCATTT GCAGTTTTTC 
AGCGAATTTG GCAATAGTGA TATTTATGTG TCACTGGCAG GCAAAAAAAA ACATGGAGCA 
CCGACTAACT ATGGATTCTG CTTTAAGCCT AACAAAGCGG GAGGGCCCCG AGACCTGAAA 
ATGCTCTGTG CAGAAGAAGA GCAGAGTAGG ACGTGCTGGG TGACCGCGAT TAGATTGCTT 
AAGTATGGCA TGCAGCTGTA CCAGAATTAT ATGCATCCAT ATCAAGGTAG AAGTGGCTGC 
AGTTCACAGA GCATATCACC TATGAGAAGT ATATCAGAGA ATTCCCTGGT AGCAATGGAC 
TTCTCAGGCC AGAAAAGCAG AGTTATAGAA AATCCCACTG AAGCCCTTTC AGTTGCGGTT 
GAAGAAGGAC TCGCTTGGAG GAAAAAAGGA TGTTTACGCC TGGGCACTCA CGGTAGCCCC 
ACTGCCTCTT CACAGAGCTC TGCCACAAAC ATGGCTATCC ACCGGTCCCA GCCATGGTTT 
CACCACAAAA TTTCTAGAGA TGAGGCTCAG CGATTGATTA TTCAGCAAGG ACTTGTGGAT 
GGAGTTTTCT TGGTACGGGA TAGTCAGAGT AACCCCAAAA CTTTCGTACT GTCAATGAGT 
CATGGACAAA AAATAAAGCA CTTTCAAATT ATACCAGTAG AAGATGACGG TGAAATGTTC 
CACACACTGG ATGATGGCCA CACAAGATTT ACAGATCTAA TACAGCTGGT GGAGTTCTAT 
CAACTCAATA AGGGCGTTCT TCCTTGCAAG TTGAAACATT ATTGTGCTAG GATTGCTCTC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004481.2
CDS	174..1796
Translation	MTTSLQDGQSAASRAAARDSPLAAQVCGAAQGRGDAHDLAPAPWLHARALLPLPDGTRGCAADRRKKKDLDVPEMPSIPNPFPELCCSPFTSVLSADLFPKANSRKKQVIKVYSEDETSRALDVPSDITARDVCQLLILKNHYIDDHSWTLFEHLPHIGVERTIEDHELVIEVLSNWGIEEENKLYFRKNYAKYEFFKNPMYFFPEHMVSFATETNGEISPTQILQMFLSSSTYPEIHGFLHAKEQGKKSWKKIYFFLRRSGLYFSTKGTSKEPRHLQFFSEFGNSDIYVSLAGKKKHGAPTNYGFCFKPNKAGGPRDLKMLCAEEEQSRTCWVTAIRLLKYGMQLYQNYMHPYQGRSGCSSQSISPMRSISENSLVAMDFSGQKSRVIENPTEALSVAVEEGLAWRKKGCLRLGTHGSPTASSQSSATNMAIHRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNPKTFVLSMSHGQKIKHFQIIPVEDDGEMFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCKLKHYCARIAL

Target ORF information:

RefSeq Version	NM_004490.3
Organism	Homo sapiens(human)
Definition	Homo sapiens growth factor receptor bound protein 14 (GRB14), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004490.3

ORF Insert Sequence:

ATGACCACTT CCCTGCAAGA TGGGCAGAGC GCCGCGAGCA GGGCGGCTGC CCGGGATTCG 
CCGCTGGCCG CCCAGGTGTG TGGCGCTGCC CAGGGGAGGG GCGACGCCCA CGACCTGGCG 
CCGGCCCCCT GGCTGCACGC GCGAGCGCTC CTGCCCCTTC CGGACGGGAC CCGCGGCTGT 
GCTGCAGACA GGAGAAAAAA GAAAGATCTT GATGTTCCGG AAATGCCATC TATTCCAAAC 
CCTTTTCCTG AGCTATGCTG TTCTCCATTT ACATCTGTGT TGTCAGCAGA CCTATTTCCC 
AAAGCAAATT CAAGGAAAAA ACAGGTGATT AAAGTATACA GTGAAGATGA AACCAGCAGG 
GCTTTAGATG TACCCAGTGA CATAACGGCT CGAGATGTTT GTCAGCTGTT GATCCTGAAG 
AATCATTACA TTGATGACCA CAGCTGGACC CTTTTTGAGC ACCTGCCTCA CATAGGTGTA 
GAAAGAACAA TAGAAGACCA CGAACTGGTG ATTGAAGTGC TATCCAACTG GGGGATAGAA 
GAAGAAAACA AACTATACTT TAGAAAAAAT TATGCCAAAT ATGAGTTCTT TAAAAACCCA 
ATGTATTTTT TTCCAGAGCA TATGGTATCT TTTGCAACTG AAACCAATGG TGAAATATCC 
CCCACACAGA TTTTGCAGAT GTTTCTGAGT TCAAGCACAT ATCCTGAAAT TCATGGTTTC 
TTACATGCGA AAGAACAGGG AAAGAAGTCT TGGAAAAAAA TTTACTTTTT TCTAAGAAGA 
TCTGGTTTAT ATTTTTCTAC TAAAGGAACA TCAAAGGAAC CGCGGCATTT GCAGTTTTTC 
AGCGAATTTG GCAATAGTGA TATTTATGTG TCACTGGCAG GCAAAAAAAA ACATGGAGCA 
CCGACTAACT ATGGATTCTG CTTTAAGCCT AACAAAGCGG GAGGGCCCCG AGACCTGAAA 
ATGCTCTGTG CAGAAGAAGA GCAGAGTAGG ACGTGCTGGG TGACCGCGAT TAGATTGCTT 
AAGTATGGCA TGCAGCTGTA CCAGAATTAT ATGCATCCAT ATCAAGGTAG AAGTGGCTGC 
AGTTCACAGA GCATATCACC TATGAGAAGT ATATCAGAGA ATTCCCTGGT AGCAATGGAC 
TTCTCAGGCC AGAAAAGCAG AGTTATAGAA AATCCCACTG AAGCCCTTTC AGTTGCGGTT 
GAAGAAGGAC TCGCTTGGAG GAAAAAAGGA TGTTTACGCC TGGGCACTCA CGGTAGCCCC 
ACTGCCTCTT CACAGAGCTC TGCCACAAAC ATGGCTATCC ACCGGTCCCA GCCATGGTTT 
CACCACAAAA TTTCTAGAGA TGAGGCTCAG CGATTGATTA TTCAGCAAGG ACTTGTGGAT 
GGAGTTTTCT TGGTACGGGA TAGTCAGAGT AACCCCAAAA CTTTCGTACT GTCAATGAGT 
CATGGACAAA AAATAAAGCA CTTTCAAATT ATACCAGTAG AAGATGACGG TGAAATGTTC 
CACACACTGG ATGATGGCCA CACAAGATTT ACAGATCTAA TACAGCTGGT GGAGTTCTAT 
CAACTCAATA AGGGCGTTCT TCCTTGCAAG TTGAAACATT ATTGTGCTAG GATTGCTCTC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GRB14 ( NM_004490.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_004481.2 Homo sapiens growth factor receptor bound protein 14 (GRB14), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu13500
Clone ID Related Accession (Same CDS sequence)	NM_004490.3 , NM_004490.2
Accession Version	NM_004490.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1623bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Homo sapiens(human)
Product	growth factor receptor-bound protein 14 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC107075.4 and BC053559.1. This sequence is a reference standard in the RefSeqGene project. On or before Mar 4, 2006 this sequence version replaced XM_944164.1, XM_944166.1, XM_944172.1, XM_944177.1, XM_939493.1, NM_004490.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC053559.1, L76687.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968189, SAMEA1968540 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACCACTT CCCTGCAAGA TGGGCAGAGC GCCGCGAGCA GGGCGGCTGC CCGGGATTCG 
CCGCTGGCCG CCCAGGTGTG TGGCGCTGCC CAGGGGAGGG GCGACGCCCA CGACCTGGCG 
CCGGCCCCCT GGCTGCACGC GCGAGCGCTC CTGCCCCTTC CGGACGGGAC CCGCGGCTGT 
GCTGCAGACA GGAGAAAAAA GAAAGATCTT GATGTTCCGG AAATGCCATC TATTCCAAAC 
CCTTTTCCTG AGCTATGCTG TTCTCCATTT ACATCTGTGT TGTCAGCAGA CCTATTTCCC 
AAAGCAAATT CAAGGAAAAA ACAGGTGATT AAAGTATACA GTGAAGATGA AACCAGCAGG 
GCTTTAGATG TACCCAGTGA CATAACGGCT CGAGATGTTT GTCAGCTGTT GATCCTGAAG 
AATCATTACA TTGATGACCA CAGCTGGACC CTTTTTGAGC ACCTGCCTCA CATAGGTGTA 
GAAAGAACAA TAGAAGACCA CGAACTGGTG ATTGAAGTGC TATCCAACTG GGGGATAGAA 
GAAGAAAACA AACTATACTT TAGAAAAAAT TATGCCAAAT ATGAGTTCTT TAAAAACCCA 
ATGTATTTTT TTCCAGAGCA TATGGTATCT TTTGCAACTG AAACCAATGG TGAAATATCC 
CCCACACAGA TTTTGCAGAT GTTTCTGAGT TCAAGCACAT ATCCTGAAAT TCATGGTTTC 
TTACATGCGA AAGAACAGGG AAAGAAGTCT TGGAAAAAAA TTTACTTTTT TCTAAGAAGA 
TCTGGTTTAT ATTTTTCTAC TAAAGGAACA TCAAAGGAAC CGCGGCATTT GCAGTTTTTC 
AGCGAATTTG GCAATAGTGA TATTTATGTG TCACTGGCAG GCAAAAAAAA ACATGGAGCA 
CCGACTAACT ATGGATTCTG CTTTAAGCCT AACAAAGCGG GAGGGCCCCG AGACCTGAAA 
ATGCTCTGTG CAGAAGAAGA GCAGAGTAGG ACGTGCTGGG TGACCGCGAT TAGATTGCTT 
AAGTATGGCA TGCAGCTGTA CCAGAATTAT ATGCATCCAT ATCAAGGTAG AAGTGGCTGC 
AGTTCACAGA GCATATCACC TATGAGAAGT ATATCAGAGA ATTCCCTGGT AGCAATGGAC 
TTCTCAGGCC AGAAAAGCAG AGTTATAGAA AATCCCACTG AAGCCCTTTC AGTTGCGGTT 
GAAGAAGGAC TCGCTTGGAG GAAAAAAGGA TGTTTACGCC TGGGCACTCA CGGTAGCCCC 
ACTGCCTCTT CACAGAGCTC TGCCACAAAC ATGGCTATCC ACCGGTCCCA GCCATGGTTT 
CACCACAAAA TTTCTAGAGA TGAGGCTCAG CGATTGATTA TTCAGCAAGG ACTTGTGGAT 
GGAGTTTTCT TGGTACGGGA TAGTCAGAGT AACCCCAAAA CTTTCGTACT GTCAATGAGT 
CATGGACAAA AAATAAAGCA CTTTCAAATT ATACCAGTAG AAGATGACGG TGAAATGTTC 
CACACACTGG ATGATGGCCA CACAAGATTT ACAGATCTAA TACAGCTGGT GGAGTTCTAT 
CAACTCAATA AGGGCGTTCT TCCTTGCAAG TTGAAACATT ATTGTGCTAG GATTGCTCTC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004481.2
CDS	542..2164
Translation	MTTSLQDGQSAASRAAARDSPLAAQVCGAAQGRGDAHDLAPAPWLHARALLPLPDGTRGCAADRRKKKDLDVPEMPSIPNPFPELCCSPFTSVLSADLFPKANSRKKQVIKVYSEDETSRALDVPSDITARDVCQLLILKNHYIDDHSWTLFEHLPHIGVERTIEDHELVIEVLSNWGIEEENKLYFRKNYAKYEFFKNPMYFFPEHMVSFATETNGEISPTQILQMFLSSSTYPEIHGFLHAKEQGKKSWKKIYFFLRRSGLYFSTKGTSKEPRHLQFFSEFGNSDIYVSLAGKKKHGAPTNYGFCFKPNKAGGPRDLKMLCAEEEQSRTCWVTAIRLLKYGMQLYQNYMHPYQGRSGCSSQSISPMRSISENSLVAMDFSGQKSRVIENPTEALSVAVEEGLAWRKKGCLRLGTHGSPTASSQSSATNMAIHRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNPKTFVLSMSHGQKIKHFQIIPVEDDGEMFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCKLKHYCARIAL

Target ORF information:

RefSeq Version	NM_004490.2
Organism	Homo sapiens(human)
Definition	Homo sapiens growth factor receptor bound protein 14 (GRB14), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004490.2

ORF Insert Sequence:

ATGACCACTT CCCTGCAAGA TGGGCAGAGC GCCGCGAGCA GGGCGGCTGC CCGGGATTCG 
CCGCTGGCCG CCCAGGTGTG TGGCGCTGCC CAGGGGAGGG GCGACGCCCA CGACCTGGCG 
CCGGCCCCCT GGCTGCACGC GCGAGCGCTC CTGCCCCTTC CGGACGGGAC CCGCGGCTGT 
GCTGCAGACA GGAGAAAAAA GAAAGATCTT GATGTTCCGG AAATGCCATC TATTCCAAAC 
CCTTTTCCTG AGCTATGCTG TTCTCCATTT ACATCTGTGT TGTCAGCAGA CCTATTTCCC 
AAAGCAAATT CAAGGAAAAA ACAGGTGATT AAAGTATACA GTGAAGATGA AACCAGCAGG 
GCTTTAGATG TACCCAGTGA CATAACGGCT CGAGATGTTT GTCAGCTGTT GATCCTGAAG 
AATCATTACA TTGATGACCA CAGCTGGACC CTTTTTGAGC ACCTGCCTCA CATAGGTGTA 
GAAAGAACAA TAGAAGACCA CGAACTGGTG ATTGAAGTGC TATCCAACTG GGGGATAGAA 
GAAGAAAACA AACTATACTT TAGAAAAAAT TATGCCAAAT ATGAGTTCTT TAAAAACCCA 
ATGTATTTTT TTCCAGAGCA TATGGTATCT TTTGCAACTG AAACCAATGG TGAAATATCC 
CCCACACAGA TTTTGCAGAT GTTTCTGAGT TCAAGCACAT ATCCTGAAAT TCATGGTTTC 
TTACATGCGA AAGAACAGGG AAAGAAGTCT TGGAAAAAAA TTTACTTTTT TCTAAGAAGA 
TCTGGTTTAT ATTTTTCTAC TAAAGGAACA TCAAAGGAAC CGCGGCATTT GCAGTTTTTC 
AGCGAATTTG GCAATAGTGA TATTTATGTG TCACTGGCAG GCAAAAAAAA ACATGGAGCA 
CCGACTAACT ATGGATTCTG CTTTAAGCCT AACAAAGCGG GAGGGCCCCG AGACCTGAAA 
ATGCTCTGTG CAGAAGAAGA GCAGAGTAGG ACGTGCTGGG TGACCGCGAT TAGATTGCTT 
AAGTATGGCA TGCAGCTGTA CCAGAATTAT ATGCATCCAT ATCAAGGTAG AAGTGGCTGC 
AGTTCACAGA GCATATCACC TATGAGAAGT ATATCAGAGA ATTCCCTGGT AGCAATGGAC 
TTCTCAGGCC AGAAAAGCAG AGTTATAGAA AATCCCACTG AAGCCCTTTC AGTTGCGGTT 
GAAGAAGGAC TCGCTTGGAG GAAAAAAGGA TGTTTACGCC TGGGCACTCA CGGTAGCCCC 
ACTGCCTCTT CACAGAGCTC TGCCACAAAC ATGGCTATCC ACCGGTCCCA GCCATGGTTT 
CACCACAAAA TTTCTAGAGA TGAGGCTCAG CGATTGATTA TTCAGCAAGG ACTTGTGGAT 
GGAGTTTTCT TGGTACGGGA TAGTCAGAGT AACCCCAAAA CTTTCGTACT GTCAATGAGT 
CATGGACAAA AAATAAAGCA CTTTCAAATT ATACCAGTAG AAGATGACGG TGAAATGTTC 
CACACACTGG ATGATGGCCA CACAAGATTT ACAGATCTAA TACAGCTGGT GGAGTTCTAT 
CAACTCAATA AGGGCGTTCT TCCTTGCAAG TTGAAACATT ATTGTGCTAG GATTGCTCTC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GRB14 ( NM_001303422.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001290351.1 Homo sapiens growth factor receptor bound protein 14 (GRB14), transcript variant 2, mRNA.

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CloneID	OHu36145
Clone ID Related Accession (Same CDS sequence)	NM_001303422.1 , NM_001303422.2
Accession Version	NM_001303422.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1362bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-29
Organism	Homo sapiens(human)
Product	growth factor receptor-bound protein 14 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC359097.1, AK301961.1, AC107075.4, CN266581.1 and DB560753.1. On Dec 31, 2014 this sequence version replaced XM_005246477.2. Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK301961.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1966682, SAMEA1968189 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGTTTGA GTGCAAGAAG AGTCACTCTG CCTGCAATAA CGCCAATAAT TCTACAGAAA 
AGGGTGATTA AAGTATACAG TGAAGATGAA ACCAGCAGGG CTTTAGATGT ACCCAGTGAC 
ATAACGGCTC GAGATGTTTG TCAGCTGTTG ATCCTGAAGA ATCATTACAT TGATGACCAC 
AGCTGGACCC TTTTTGAGCA CCTGCCTCAC ATAGGTGTAG AAAGAACAAT AGAAGACCAC 
GAACTGGTGA TTGAAGTGCT ATCCAACTGG GGGATAGAAG AAGAAAACAA ACTATACTTT 
AGAAAAAATT ATGCCAAATA TGAGTTCTTT AAAAACCCAA TGTATTTTTT TCCAGAGCAT 
ATGGTATCTT TTGCAACTGA AACCAATGGT GAAATATCCC CCACACAGAT TTTGCAGATG 
TTTCTGAGTT CAAGCACATA TCCTGAAATT CATGGTTTCT TACATGCGAA AGAACAGGGA 
AAGAAGTCTT GGAAAAAAAT TTACTTTTTT CTAAGAAGAT CTGGTTTATA TTTTTCTACT 
AAAGGAACAT CAAAGGAACC GCGGCATTTG CAGTTTTTCA GCGAATTTGG CAATAGTGAT 
ATTTATGTGT CACTGGCAGG CAAAAAAAAA CATGGAGCAC CGACTAACTA TGGATTCTGC 
TTTAAGCCTA ACAAAGCGGG AGGGCCCCGA GACCTGAAAA TGCTCTGTGC AGAAGAAGAG 
CAGAGTAGGA CGTGCTGGGT GACCGCGATT AGATTGCTTA AGTATGGCAT GCAGCTGTAC 
CAGAATTATA TGCATCCATA TCAAGGTAGA AGTGGCTGCA GTTCACAGAG CATATCACCT 
ATGAGAAGTA TATCAGAGAA TTCCCTGGTA GCAATGGACT TCTCAGGCCA GAAAAGCAGA 
GTTATAGAAA ATCCCACTGA AGCCCTTTCA GTTGCGGTTG AAGAAGGACT CGCTTGGAGG 
AAAAAAGGAT GTTTACGCCT GGGCACTCAC GGTAGCCCCA CTGCCTCTTC ACAGAGCTCT 
GCCACAAACA TGGCTATCCA CCGGTCCCAG CCATGGTTTC ACCACAAAAT TTCTAGAGAT 
GAGGCTCAGC GATTGATTAT TCAGCAAGGA CTTGTGGATG GAGTTTTCTT GGTACGGGAT 
AGTCAGAGTA ACCCCAAAAC TTTCGTACTG TCAATGAGTC ATGGACAAAA AATAAAGCAC 
TTTCAAATTA TACCAGTAGA AGATGACGGT GAAATGTTCC ACACACTGGA TGATGGCCAC 
ACAAGATTTA CAGATCTAAT ACAGCTGGTG GAGTTCTATC AACTCAATAA GGGCGTTCTT 
CCTTGCAAGT TGAAACATTA TTGTGCTAGG ATTGCTCTCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001290351.1
CDS	174..1535
Translation	MSLSARRVTLPAITPIILQKRVIKVYSEDETSRALDVPSDITARDVCQLLILKNHYIDDHSWTLFEHLPHIGVERTIEDHELVIEVLSNWGIEEENKLYFRKNYAKYEFFKNPMYFFPEHMVSFATETNGEISPTQILQMFLSSSTYPEIHGFLHAKEQGKKSWKKIYFFLRRSGLYFSTKGTSKEPRHLQFFSEFGNSDIYVSLAGKKKHGAPTNYGFCFKPNKAGGPRDLKMLCAEEEQSRTCWVTAIRLLKYGMQLYQNYMHPYQGRSGCSSQSISPMRSISENSLVAMDFSGQKSRVIENPTEALSVAVEEGLAWRKKGCLRLGTHGSPTASSQSSATNMAIHRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNPKTFVLSMSHGQKIKHFQIIPVEDDGEMFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCKLKHYCARIAL

Target ORF information:

RefSeq Version	NM_001303422.1
Organism	Homo sapiens(human)
Definition	Homo sapiens growth factor receptor bound protein 14 (GRB14), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001303422.1

ORF Insert Sequence:

ATGAGTTTGA GTGCAAGAAG AGTCACTCTG CCTGCAATAA CGCCAATAAT TCTACAGAAA 
AGGGTGATTA AAGTATACAG TGAAGATGAA ACCAGCAGGG CTTTAGATGT ACCCAGTGAC 
ATAACGGCTC GAGATGTTTG TCAGCTGTTG ATCCTGAAGA ATCATTACAT TGATGACCAC 
AGCTGGACCC TTTTTGAGCA CCTGCCTCAC ATAGGTGTAG AAAGAACAAT AGAAGACCAC 
GAACTGGTGA TTGAAGTGCT ATCCAACTGG GGGATAGAAG AAGAAAACAA ACTATACTTT 
AGAAAAAATT ATGCCAAATA TGAGTTCTTT AAAAACCCAA TGTATTTTTT TCCAGAGCAT 
ATGGTATCTT TTGCAACTGA AACCAATGGT GAAATATCCC CCACACAGAT TTTGCAGATG 
TTTCTGAGTT CAAGCACATA TCCTGAAATT CATGGTTTCT TACATGCGAA AGAACAGGGA 
AAGAAGTCTT GGAAAAAAAT TTACTTTTTT CTAAGAAGAT CTGGTTTATA TTTTTCTACT 
AAAGGAACAT CAAAGGAACC GCGGCATTTG CAGTTTTTCA GCGAATTTGG CAATAGTGAT 
ATTTATGTGT CACTGGCAGG CAAAAAAAAA CATGGAGCAC CGACTAACTA TGGATTCTGC 
TTTAAGCCTA ACAAAGCGGG AGGGCCCCGA GACCTGAAAA TGCTCTGTGC AGAAGAAGAG 
CAGAGTAGGA CGTGCTGGGT GACCGCGATT AGATTGCTTA AGTATGGCAT GCAGCTGTAC 
CAGAATTATA TGCATCCATA TCAAGGTAGA AGTGGCTGCA GTTCACAGAG CATATCACCT 
ATGAGAAGTA TATCAGAGAA TTCCCTGGTA GCAATGGACT TCTCAGGCCA GAAAAGCAGA 
GTTATAGAAA ATCCCACTGA AGCCCTTTCA GTTGCGGTTG AAGAAGGACT CGCTTGGAGG 
AAAAAAGGAT GTTTACGCCT GGGCACTCAC GGTAGCCCCA CTGCCTCTTC ACAGAGCTCT 
GCCACAAACA TGGCTATCCA CCGGTCCCAG CCATGGTTTC ACCACAAAAT TTCTAGAGAT 
GAGGCTCAGC GATTGATTAT TCAGCAAGGA CTTGTGGATG GAGTTTTCTT GGTACGGGAT 
AGTCAGAGTA ACCCCAAAAC TTTCGTACTG TCAATGAGTC ATGGACAAAA AATAAAGCAC 
TTTCAAATTA TACCAGTAGA AGATGACGGT GAAATGTTCC ACACACTGGA TGATGGCCAC 
ACAAGATTTA CAGATCTAAT ACAGCTGGTG GAGTTCTATC AACTCAATAA GGGCGTTCTT 
CCTTGCAAGT TGAAACATTA TTGTGCTAGG ATTGCTCTCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GRB14 ( NM_001303422.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001290351.1 Homo sapiens growth factor receptor bound protein 14 (GRB14), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu36145
Clone ID Related Accession (Same CDS sequence)	NM_001303422.1 , NM_001303422.2
Accession Version	NM_001303422.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1362bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-30
Organism	Homo sapiens(human)
Product	growth factor receptor-bound protein 14 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK301961.1, AC107075.4, CN266581.1 and DB560753.1. On May 31, 2019 this sequence version replaced NM_001303422.1. Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK301961.1, SRR5189667.282123.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1966682, SAMEA1968189 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGTTTGA GTGCAAGAAG AGTCACTCTG CCTGCAATAA CGCCAATAAT TCTACAGAAA 
AGGGTGATTA AAGTATACAG TGAAGATGAA ACCAGCAGGG CTTTAGATGT ACCCAGTGAC 
ATAACGGCTC GAGATGTTTG TCAGCTGTTG ATCCTGAAGA ATCATTACAT TGATGACCAC 
AGCTGGACCC TTTTTGAGCA CCTGCCTCAC ATAGGTGTAG AAAGAACAAT AGAAGACCAC 
GAACTGGTGA TTGAAGTGCT ATCCAACTGG GGGATAGAAG AAGAAAACAA ACTATACTTT 
AGAAAAAATT ATGCCAAATA TGAGTTCTTT AAAAACCCAA TGTATTTTTT TCCAGAGCAT 
ATGGTATCTT TTGCAACTGA AACCAATGGT GAAATATCCC CCACACAGAT TTTGCAGATG 
TTTCTGAGTT CAAGCACATA TCCTGAAATT CATGGTTTCT TACATGCGAA AGAACAGGGA 
AAGAAGTCTT GGAAAAAAAT TTACTTTTTT CTAAGAAGAT CTGGTTTATA TTTTTCTACT 
AAAGGAACAT CAAAGGAACC GCGGCATTTG CAGTTTTTCA GCGAATTTGG CAATAGTGAT 
ATTTATGTGT CACTGGCAGG CAAAAAAAAA CATGGAGCAC CGACTAACTA TGGATTCTGC 
TTTAAGCCTA ACAAAGCGGG AGGGCCCCGA GACCTGAAAA TGCTCTGTGC AGAAGAAGAG 
CAGAGTAGGA CGTGCTGGGT GACCGCGATT AGATTGCTTA AGTATGGCAT GCAGCTGTAC 
CAGAATTATA TGCATCCATA TCAAGGTAGA AGTGGCTGCA GTTCACAGAG CATATCACCT 
ATGAGAAGTA TATCAGAGAA TTCCCTGGTA GCAATGGACT TCTCAGGCCA GAAAAGCAGA 
GTTATAGAAA ATCCCACTGA AGCCCTTTCA GTTGCGGTTG AAGAAGGACT CGCTTGGAGG 
AAAAAAGGAT GTTTACGCCT GGGCACTCAC GGTAGCCCCA CTGCCTCTTC ACAGAGCTCT 
GCCACAAACA TGGCTATCCA CCGGTCCCAG CCATGGTTTC ACCACAAAAT TTCTAGAGAT 
GAGGCTCAGC GATTGATTAT TCAGCAAGGA CTTGTGGATG GAGTTTTCTT GGTACGGGAT 
AGTCAGAGTA ACCCCAAAAC TTTCGTACTG TCAATGAGTC ATGGACAAAA AATAAAGCAC 
TTTCAAATTA TACCAGTAGA AGATGACGGT GAAATGTTCC ACACACTGGA TGATGGCCAC 
ACAAGATTTA CAGATCTAAT ACAGCTGGTG GAGTTCTATC AACTCAATAA GGGCGTTCTT 
CCTTGCAAGT TGAAACATTA TTGTGCTAGG ATTGCTCTCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001290351.1
CDS	119..1480
Translation	MSLSARRVTLPAITPIILQKRVIKVYSEDETSRALDVPSDITARDVCQLLILKNHYIDDHSWTLFEHLPHIGVERTIEDHELVIEVLSNWGIEEENKLYFRKNYAKYEFFKNPMYFFPEHMVSFATETNGEISPTQILQMFLSSSTYPEIHGFLHAKEQGKKSWKKIYFFLRRSGLYFSTKGTSKEPRHLQFFSEFGNSDIYVSLAGKKKHGAPTNYGFCFKPNKAGGPRDLKMLCAEEEQSRTCWVTAIRLLKYGMQLYQNYMHPYQGRSGCSSQSISPMRSISENSLVAMDFSGQKSRVIENPTEALSVAVEEGLAWRKKGCLRLGTHGSPTASSQSSATNMAIHRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNPKTFVLSMSHGQKIKHFQIIPVEDDGEMFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCKLKHYCARIAL

Target ORF information:

RefSeq Version	NM_001303422.2
Organism	Homo sapiens(human)
Definition	Homo sapiens growth factor receptor bound protein 14 (GRB14), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001303422.2

ORF Insert Sequence:

ATGAGTTTGA GTGCAAGAAG AGTCACTCTG CCTGCAATAA CGCCAATAAT TCTACAGAAA 
AGGGTGATTA AAGTATACAG TGAAGATGAA ACCAGCAGGG CTTTAGATGT ACCCAGTGAC 
ATAACGGCTC GAGATGTTTG TCAGCTGTTG ATCCTGAAGA ATCATTACAT TGATGACCAC 
AGCTGGACCC TTTTTGAGCA CCTGCCTCAC ATAGGTGTAG AAAGAACAAT AGAAGACCAC 
GAACTGGTGA TTGAAGTGCT ATCCAACTGG GGGATAGAAG AAGAAAACAA ACTATACTTT 
AGAAAAAATT ATGCCAAATA TGAGTTCTTT AAAAACCCAA TGTATTTTTT TCCAGAGCAT 
ATGGTATCTT TTGCAACTGA AACCAATGGT GAAATATCCC CCACACAGAT TTTGCAGATG 
TTTCTGAGTT CAAGCACATA TCCTGAAATT CATGGTTTCT TACATGCGAA AGAACAGGGA 
AAGAAGTCTT GGAAAAAAAT TTACTTTTTT CTAAGAAGAT CTGGTTTATA TTTTTCTACT 
AAAGGAACAT CAAAGGAACC GCGGCATTTG CAGTTTTTCA GCGAATTTGG CAATAGTGAT 
ATTTATGTGT CACTGGCAGG CAAAAAAAAA CATGGAGCAC CGACTAACTA TGGATTCTGC 
TTTAAGCCTA ACAAAGCGGG AGGGCCCCGA GACCTGAAAA TGCTCTGTGC AGAAGAAGAG 
CAGAGTAGGA CGTGCTGGGT GACCGCGATT AGATTGCTTA AGTATGGCAT GCAGCTGTAC 
CAGAATTATA TGCATCCATA TCAAGGTAGA AGTGGCTGCA GTTCACAGAG CATATCACCT 
ATGAGAAGTA TATCAGAGAA TTCCCTGGTA GCAATGGACT TCTCAGGCCA GAAAAGCAGA 
GTTATAGAAA ATCCCACTGA AGCCCTTTCA GTTGCGGTTG AAGAAGGACT CGCTTGGAGG 
AAAAAAGGAT GTTTACGCCT GGGCACTCAC GGTAGCCCCA CTGCCTCTTC ACAGAGCTCT 
GCCACAAACA TGGCTATCCA CCGGTCCCAG CCATGGTTTC ACCACAAAAT TTCTAGAGAT 
GAGGCTCAGC GATTGATTAT TCAGCAAGGA CTTGTGGATG GAGTTTTCTT GGTACGGGAT 
AGTCAGAGTA ACCCCAAAAC TTTCGTACTG TCAATGAGTC ATGGACAAAA AATAAAGCAC 
TTTCAAATTA TACCAGTAGA AGATGACGGT GAAATGTTCC ACACACTGGA TGATGGCCAC 
ACAAGATTTA CAGATCTAAT ACAGCTGGTG GAGTTCTATC AACTCAATAA GGGCGTTCTT 
CCTTGCAAGT TGAAACATTA TTGTGCTAGG ATTGCTCTCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GRB14 ( XM_011511022.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011509324.1 Homo sapiens growth factor receptor bound protein 14 (GRB14), transcript variant X5, mRNA.

Price & Availability↑

CloneID	OHu58055
Clone ID Related Accession (Same CDS sequence)	XM_011511022.2
Accession Version	XM_011511022.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 939bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	growth factor receptor-bound protein 14 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011511022.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCACTT CCCTGCAAGA TGGGCAGAGC GCCGCGAGCA GGGCGGCTGC CCGGGATTCG 
CCGCTGGCCG CCCAGGTGTG TGGCGCTGCC CAGGGGAGGG GCGACGCCCA CGACCTGGCG 
CCGGCCCCCT GGCTGCACGC GCGAGCGCTC CTGCCCCTTC CGGACGGGAC CCGCGGCTGT 
GCTGCAGACA GGAGAAAAAA GAAAGATCTT GATGTTCCGG AAATGCCATC TATTCCAAAC 
CCTTTTCCTG AGCTATGCTG TTCTCCATTT ACATCTGTGT TGTCAGCAGA CCTATTTCCC 
AAAGCAAATT CAAGGAAAAA ACAGGTGATT AAAGTATACA GTGAAGATGA AACCAGCAGG 
GCTTTAGATG TACCCAGTGA CATAACGGCT CGAGATGTTT GTCAGCTGTT GATCCTGAAG 
AATCATTACA TTGATGACCA CAGCTGGACC CTTTTTGAGC ACCTGCCTCA CATAGGTGTA 
GAAAGAACAA TAGAAGACCA CGAACTGGTG ATTGAAGTGC TATCCAACTG GGGGATAGAA 
GAAGAAAACA AACTATACTT TAGAAAAAAT TATGCCAAAT ATGAGTTCTT TAAAAACCCA 
ATGTATTTTT TTCCAGAGCA TATGGTATCT TTTGCAACTG AAACCAATGG TGAAATATCC 
CCCACACAGA TTTTGCAGAT GTTTCTGAGT TCAAGCACAT ATCCTGAAAT TCATGGTTTC 
TTACATGCGA AAGAACAGGG AAAGAAGTCT TGGAAAAAAA TTTACTTTTT TCTAAGAAGA 
TCTGGTTTAT ATTTTTCTAC TAAAGGAACA TCAAAGGAAC CGCGGCATTT GCAGTTTTTC 
AGCGAATTTG GCAATAGTGA TATTTATGTG TCACTGGCAG GCAAAAAAAA ACATGGAGCA 
CCGACTAACT ATGGATTCTG CTTTAAGGTA CAGGCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011509324.1
CDS	174..1112
Translation	MTTSLQDGQSAASRAAARDSPLAAQVCGAAQGRGDAHDLAPAPWLHARALLPLPDGTRGCAADRRKKKDLDVPEMPSIPNPFPELCCSPFTSVLSADLFPKANSRKKQVIKVYSEDETSRALDVPSDITARDVCQLLILKNHYIDDHSWTLFEHLPHIGVERTIEDHELVIEVLSNWGIEEENKLYFRKNYAKYEFFKNPMYFFPEHMVSFATETNGEISPTQILQMFLSSSTYPEIHGFLHAKEQGKKSWKKIYFFLRRSGLYFSTKGTSKEPRHLQFFSEFGNSDIYVSLAGKKKHGAPTNYGFCFKVQA

Target ORF information:

RefSeq Version	XM_011511022.2
Organism	Homo sapiens(human)
Definition	Homo sapiens growth factor receptor bound protein 14 (GRB14), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011511022.2

ORF Insert Sequence:

ATGACCACTT CCCTGCAAGA TGGGCAGAGC GCCGCGAGCA GGGCGGCTGC CCGGGATTCG 
CCGCTGGCCG CCCAGGTGTG TGGCGCTGCC CAGGGGAGGG GCGACGCCCA CGACCTGGCG 
CCGGCCCCCT GGCTGCACGC GCGAGCGCTC CTGCCCCTTC CGGACGGGAC CCGCGGCTGT 
GCTGCAGACA GGAGAAAAAA GAAAGATCTT GATGTTCCGG AAATGCCATC TATTCCAAAC 
CCTTTTCCTG AGCTATGCTG TTCTCCATTT ACATCTGTGT TGTCAGCAGA CCTATTTCCC 
AAAGCAAATT CAAGGAAAAA ACAGGTGATT AAAGTATACA GTGAAGATGA AACCAGCAGG 
GCTTTAGATG TACCCAGTGA CATAACGGCT CGAGATGTTT GTCAGCTGTT GATCCTGAAG 
AATCATTACA TTGATGACCA CAGCTGGACC CTTTTTGAGC ACCTGCCTCA CATAGGTGTA 
GAAAGAACAA TAGAAGACCA CGAACTGGTG ATTGAAGTGC TATCCAACTG GGGGATAGAA 
GAAGAAAACA AACTATACTT TAGAAAAAAT TATGCCAAAT ATGAGTTCTT TAAAAACCCA 
ATGTATTTTT TTCCAGAGCA TATGGTATCT TTTGCAACTG AAACCAATGG TGAAATATCC 
CCCACACAGA TTTTGCAGAT GTTTCTGAGT TCAAGCACAT ATCCTGAAAT TCATGGTTTC 
TTACATGCGA AAGAACAGGG AAAGAAGTCT TGGAAAAAAA TTTACTTTTT TCTAAGAAGA 
TCTGGTTTAT ATTTTTCTAC TAAAGGAACA TCAAAGGAAC CGCGGCATTT GCAGTTTTTC 
AGCGAATTTG GCAATAGTGA TATTTATGTG TCACTGGCAG GCAAAAAAAA ACATGGAGCA 
CCGACTAACT ATGGATTCTG CTTTAAGGTA CAGGCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GRB14 ( XM_024452815.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024308583.1 Homo sapiens growth factor receptor bound protein 14 (GRB14), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu104860
Clone ID Related Accession (Same CDS sequence)	XM_024452815.1 , XM_024452816.1
Accession Version	XM_024452815.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1401bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	growth factor receptor-bound protein 14 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCATCTA TTCCAAACCC TTTTCCTGAG CTATGCTGTT CTCCATTTAC ATCTGTGTTG 
TCAGCAGACC TATTTCCCAA AGCAAATTCA AGGAAAAAAC AGGTGATTAA AGTATACAGT 
GAAGATGAAA CCAGCAGGGC TTTAGATGTA CCCAGTGACA TAACGGCTCG AGATGTTTGT 
CAGCTGTTGA TCCTGAAGAA TCATTACATT GATGACCACA GCTGGACCCT TTTTGAGCAC 
CTGCCTCACA TAGGTGTAGA AAGAACAATA GAAGACCACG AACTGGTGAT TGAAGTGCTA 
TCCAACTGGG GGATAGAAGA AGAAAACAAA CTATACTTTA GAAAAAATTA TGCCAAATAT 
GAGTTCTTTA AAAACCCAAT GTATTTTTTT CCAGAGCATA TGGTATCTTT TGCAACTGAA 
ACCAATGGTG AAATATCCCC CACACAGATT TTGCAGATGT TTCTGAGTTC AAGCACATAT 
CCTGAAATTC ATGGTTTCTT ACATGCGAAA GAACAGGGAA AGAAGTCTTG GAAAAAAATT 
TACTTTTTTC TAAGAAGATC TGGTTTATAT TTTTCTACTA AAGGAACATC AAAGGAACCG 
CGGCATTTGC AGTTTTTCAG CGAATTTGGC AATAGTGATA TTTATGTGTC ACTGGCAGGC 
AAAAAAAAAC ATGGAGCACC GACTAACTAT GGATTCTGCT TTAAGCCTAA CAAAGCGGGA 
GGGCCCCGAG ACCTGAAAAT GCTCTGTGCA GAAGAAGAGC AGAGTAGGAC GTGCTGGGTG 
ACCGCGATTA GATTGCTTAA GTATGGCATG CAGCTGTACC AGAATTATAT GCATCCATAT 
CAAGGTAGAA GTGGCTGCAG TTCACAGAGC ATATCACCTA TGAGAAGTAT ATCAGAGAAT 
TCCCTGGTAG CAATGGACTT CTCAGGCCAG AAAAGCAGAG TTATAGAAAA TCCCACTGAA 
GCCCTTTCAG TTGCGGTTGA AGAAGGACTC GCTTGGAGGA AAAAAGGATG TTTACGCCTG 
GGCACTCACG GTAGCCCCAC TGCCTCTTCA CAGAGCTCTG CCACAAACAT GGCTATCCAC 
CGGTCCCAGC CATGGTTTCA CCACAAAATT TCTAGAGATG AGGCTCAGCG ATTGATTATT 
CAGCAAGGAC TTGTGGATGG AGTTTTCTTG GTACGGGATA GTCAGAGTAA CCCCAAAACT 
TTCGTACTGT CAATGAGTCA TGGACAAAAA ATAAAGCACT TTCAAATTAT ACCAGTAGAA 
GATGACGGTG AAATGTTCCA CACACTGGAT GATGGCCACA CAAGATTTAC AGATCTAATA 
CAGCTGGTGG AGTTCTATCA ACTCAATAAG GGCGTTCTTC CTTGCAAGTT GAAACATTAT 
TGTGCTAGGA TTGCTCTCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024308583.1
CDS	619..2019
Translation	MPSIPNPFPELCCSPFTSVLSADLFPKANSRKKQVIKVYSEDETSRALDVPSDITARDVCQLLILKNHYIDDHSWTLFEHLPHIGVERTIEDHELVIEVLSNWGIEEENKLYFRKNYAKYEFFKNPMYFFPEHMVSFATETNGEISPTQILQMFLSSSTYPEIHGFLHAKEQGKKSWKKIYFFLRRSGLYFSTKGTSKEPRHLQFFSEFGNSDIYVSLAGKKKHGAPTNYGFCFKPNKAGGPRDLKMLCAEEEQSRTCWVTAIRLLKYGMQLYQNYMHPYQGRSGCSSQSISPMRSISENSLVAMDFSGQKSRVIENPTEALSVAVEEGLAWRKKGCLRLGTHGSPTASSQSSATNMAIHRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNPKTFVLSMSHGQKIKHFQIIPVEDDGEMFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCKLKHYCARIAL

Target ORF information:

RefSeq Version	XM_024452815.1
Organism	Homo sapiens(human)
Definition	Homo sapiens growth factor receptor bound protein 14 (GRB14), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024452815.1

ORF Insert Sequence:

ATGCCATCTA TTCCAAACCC TTTTCCTGAG CTATGCTGTT CTCCATTTAC ATCTGTGTTG 
TCAGCAGACC TATTTCCCAA AGCAAATTCA AGGAAAAAAC AGGTGATTAA AGTATACAGT 
GAAGATGAAA CCAGCAGGGC TTTAGATGTA CCCAGTGACA TAACGGCTCG AGATGTTTGT 
CAGCTGTTGA TCCTGAAGAA TCATTACATT GATGACCACA GCTGGACCCT TTTTGAGCAC 
CTGCCTCACA TAGGTGTAGA AAGAACAATA GAAGACCACG AACTGGTGAT TGAAGTGCTA 
TCCAACTGGG GGATAGAAGA AGAAAACAAA CTATACTTTA GAAAAAATTA TGCCAAATAT 
GAGTTCTTTA AAAACCCAAT GTATTTTTTT CCAGAGCATA TGGTATCTTT TGCAACTGAA 
ACCAATGGTG AAATATCCCC CACACAGATT TTGCAGATGT TTCTGAGTTC AAGCACATAT 
CCTGAAATTC ATGGTTTCTT ACATGCGAAA GAACAGGGAA AGAAGTCTTG GAAAAAAATT 
TACTTTTTTC TAAGAAGATC TGGTTTATAT TTTTCTACTA AAGGAACATC AAAGGAACCG 
CGGCATTTGC AGTTTTTCAG CGAATTTGGC AATAGTGATA TTTATGTGTC ACTGGCAGGC 
AAAAAAAAAC ATGGAGCACC GACTAACTAT GGATTCTGCT TTAAGCCTAA CAAAGCGGGA 
GGGCCCCGAG ACCTGAAAAT GCTCTGTGCA GAAGAAGAGC AGAGTAGGAC GTGCTGGGTG 
ACCGCGATTA GATTGCTTAA GTATGGCATG CAGCTGTACC AGAATTATAT GCATCCATAT 
CAAGGTAGAA GTGGCTGCAG TTCACAGAGC ATATCACCTA TGAGAAGTAT ATCAGAGAAT 
TCCCTGGTAG CAATGGACTT CTCAGGCCAG AAAAGCAGAG TTATAGAAAA TCCCACTGAA 
GCCCTTTCAG TTGCGGTTGA AGAAGGACTC GCTTGGAGGA AAAAAGGATG TTTACGCCTG 
GGCACTCACG GTAGCCCCAC TGCCTCTTCA CAGAGCTCTG CCACAAACAT GGCTATCCAC 
CGGTCCCAGC CATGGTTTCA CCACAAAATT TCTAGAGATG AGGCTCAGCG ATTGATTATT 
CAGCAAGGAC TTGTGGATGG AGTTTTCTTG GTACGGGATA GTCAGAGTAA CCCCAAAACT 
TTCGTACTGT CAATGAGTCA TGGACAAAAA ATAAAGCACT TTCAAATTAT ACCAGTAGAA 
GATGACGGTG AAATGTTCCA CACACTGGAT GATGGCCACA CAAGATTTAC AGATCTAATA 
CAGCTGGTGG AGTTCTATCA ACTCAATAAG GGCGTTCTTC CTTGCAAGTT GAAACATTAT 
TGTGCTAGGA TTGCTCTCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GRB14 ( XM_024452816.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024308584.1 Homo sapiens growth factor receptor bound protein 14 (GRB14), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu104860
Clone ID Related Accession (Same CDS sequence)	XM_024452815.1 , XM_024452816.1
Accession Version	XM_024452816.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1401bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	growth factor receptor-bound protein 14 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCATCTA TTCCAAACCC TTTTCCTGAG CTATGCTGTT CTCCATTTAC ATCTGTGTTG 
TCAGCAGACC TATTTCCCAA AGCAAATTCA AGGAAAAAAC AGGTGATTAA AGTATACAGT 
GAAGATGAAA CCAGCAGGGC TTTAGATGTA CCCAGTGACA TAACGGCTCG AGATGTTTGT 
CAGCTGTTGA TCCTGAAGAA TCATTACATT GATGACCACA GCTGGACCCT TTTTGAGCAC 
CTGCCTCACA TAGGTGTAGA AAGAACAATA GAAGACCACG AACTGGTGAT TGAAGTGCTA 
TCCAACTGGG GGATAGAAGA AGAAAACAAA CTATACTTTA GAAAAAATTA TGCCAAATAT 
GAGTTCTTTA AAAACCCAAT GTATTTTTTT CCAGAGCATA TGGTATCTTT TGCAACTGAA 
ACCAATGGTG AAATATCCCC CACACAGATT TTGCAGATGT TTCTGAGTTC AAGCACATAT 
CCTGAAATTC ATGGTTTCTT ACATGCGAAA GAACAGGGAA AGAAGTCTTG GAAAAAAATT 
TACTTTTTTC TAAGAAGATC TGGTTTATAT TTTTCTACTA AAGGAACATC AAAGGAACCG 
CGGCATTTGC AGTTTTTCAG CGAATTTGGC AATAGTGATA TTTATGTGTC ACTGGCAGGC 
AAAAAAAAAC ATGGAGCACC GACTAACTAT GGATTCTGCT TTAAGCCTAA CAAAGCGGGA 
GGGCCCCGAG ACCTGAAAAT GCTCTGTGCA GAAGAAGAGC AGAGTAGGAC GTGCTGGGTG 
ACCGCGATTA GATTGCTTAA GTATGGCATG CAGCTGTACC AGAATTATAT GCATCCATAT 
CAAGGTAGAA GTGGCTGCAG TTCACAGAGC ATATCACCTA TGAGAAGTAT ATCAGAGAAT 
TCCCTGGTAG CAATGGACTT CTCAGGCCAG AAAAGCAGAG TTATAGAAAA TCCCACTGAA 
GCCCTTTCAG TTGCGGTTGA AGAAGGACTC GCTTGGAGGA AAAAAGGATG TTTACGCCTG 
GGCACTCACG GTAGCCCCAC TGCCTCTTCA CAGAGCTCTG CCACAAACAT GGCTATCCAC 
CGGTCCCAGC CATGGTTTCA CCACAAAATT TCTAGAGATG AGGCTCAGCG ATTGATTATT 
CAGCAAGGAC TTGTGGATGG AGTTTTCTTG GTACGGGATA GTCAGAGTAA CCCCAAAACT 
TTCGTACTGT CAATGAGTCA TGGACAAAAA ATAAAGCACT TTCAAATTAT ACCAGTAGAA 
GATGACGGTG AAATGTTCCA CACACTGGAT GATGGCCACA CAAGATTTAC AGATCTAATA 
CAGCTGGTGG AGTTCTATCA ACTCAATAAG GGCGTTCTTC CTTGCAAGTT GAAACATTAT 
TGTGCTAGGA TTGCTCTCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024308584.1
CDS	234..1634
Translation	MPSIPNPFPELCCSPFTSVLSADLFPKANSRKKQVIKVYSEDETSRALDVPSDITARDVCQLLILKNHYIDDHSWTLFEHLPHIGVERTIEDHELVIEVLSNWGIEEENKLYFRKNYAKYEFFKNPMYFFPEHMVSFATETNGEISPTQILQMFLSSSTYPEIHGFLHAKEQGKKSWKKIYFFLRRSGLYFSTKGTSKEPRHLQFFSEFGNSDIYVSLAGKKKHGAPTNYGFCFKPNKAGGPRDLKMLCAEEEQSRTCWVTAIRLLKYGMQLYQNYMHPYQGRSGCSSQSISPMRSISENSLVAMDFSGQKSRVIENPTEALSVAVEEGLAWRKKGCLRLGTHGSPTASSQSSATNMAIHRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNPKTFVLSMSHGQKIKHFQIIPVEDDGEMFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCKLKHYCARIAL

Target ORF information:

RefSeq Version	XM_024452816.1
Organism	Homo sapiens(human)
Definition	Homo sapiens growth factor receptor bound protein 14 (GRB14), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024452816.1

ORF Insert Sequence:

ATGCCATCTA TTCCAAACCC TTTTCCTGAG CTATGCTGTT CTCCATTTAC ATCTGTGTTG 
TCAGCAGACC TATTTCCCAA AGCAAATTCA AGGAAAAAAC AGGTGATTAA AGTATACAGT 
GAAGATGAAA CCAGCAGGGC TTTAGATGTA CCCAGTGACA TAACGGCTCG AGATGTTTGT 
CAGCTGTTGA TCCTGAAGAA TCATTACATT GATGACCACA GCTGGACCCT TTTTGAGCAC 
CTGCCTCACA TAGGTGTAGA AAGAACAATA GAAGACCACG AACTGGTGAT TGAAGTGCTA 
TCCAACTGGG GGATAGAAGA AGAAAACAAA CTATACTTTA GAAAAAATTA TGCCAAATAT 
GAGTTCTTTA AAAACCCAAT GTATTTTTTT CCAGAGCATA TGGTATCTTT TGCAACTGAA 
ACCAATGGTG AAATATCCCC CACACAGATT TTGCAGATGT TTCTGAGTTC AAGCACATAT 
CCTGAAATTC ATGGTTTCTT ACATGCGAAA GAACAGGGAA AGAAGTCTTG GAAAAAAATT 
TACTTTTTTC TAAGAAGATC TGGTTTATAT TTTTCTACTA AAGGAACATC AAAGGAACCG 
CGGCATTTGC AGTTTTTCAG CGAATTTGGC AATAGTGATA TTTATGTGTC ACTGGCAGGC 
AAAAAAAAAC ATGGAGCACC GACTAACTAT GGATTCTGCT TTAAGCCTAA CAAAGCGGGA 
GGGCCCCGAG ACCTGAAAAT GCTCTGTGCA GAAGAAGAGC AGAGTAGGAC GTGCTGGGTG 
ACCGCGATTA GATTGCTTAA GTATGGCATG CAGCTGTACC AGAATTATAT GCATCCATAT 
CAAGGTAGAA GTGGCTGCAG TTCACAGAGC ATATCACCTA TGAGAAGTAT ATCAGAGAAT 
TCCCTGGTAG CAATGGACTT CTCAGGCCAG AAAAGCAGAG TTATAGAAAA TCCCACTGAA 
GCCCTTTCAG TTGCGGTTGA AGAAGGACTC GCTTGGAGGA AAAAAGGATG TTTACGCCTG 
GGCACTCACG GTAGCCCCAC TGCCTCTTCA CAGAGCTCTG CCACAAACAT GGCTATCCAC 
CGGTCCCAGC CATGGTTTCA CCACAAAATT TCTAGAGATG AGGCTCAGCG ATTGATTATT 
CAGCAAGGAC TTGTGGATGG AGTTTTCTTG GTACGGGATA GTCAGAGTAA CCCCAAAACT 
TTCGTACTGT CAATGAGTCA TGGACAAAAA ATAAAGCACT TTCAAATTAT ACCAGTAGAA 
GATGACGGTG AAATGTTCCA CACACTGGAT GATGGCCACA CAAGATTTAC AGATCTAATA 
CAGCTGGTGG AGTTCTATCA ACTCAATAAG GGCGTTCTTC CTTGCAAGTT GAAACATTAT 
TGTGCTAGGA TTGCTCTCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Phosphorylation of clustered serine residues in the N-terminus of BPS domain negatively regulates formation of the complex between human Grb14 and insulin receptor.
Journal of biochemistry162(2)113-122(2017 Aug)
Taira J,Kida Y,Inatomi K,Komatsu H,Higashimoto Y,Sakamoto H

The adaptors Grb10 and Grb14 are calmodulin-binding proteins.
FEBS letters591(8)1176-1186(2017 04)
Garc?a-Palmero I,Pompas-Veganzones N,Villalobo E,Gioria S,Haiech J,Villalobo A

Air pollution and diabetes association: Modification by type 2 diabetes genetic risk score.
Environment international94263-271(2016 Sep)
Eze IC,Imboden M,Kumar A,von Eckardstein A,Stolz D,Gerbase MW,K?nzli N,Pons M,Kronenberg F,Schindler C,Probst-Hensch N

High expression of growth factor receptor-bound protein 14 predicts poor prognosis for colorectal cancer patients.
Biotechnology letters38(6)1043-7(2016 Jun)
Yang P,Wei J,Li W,He F,Zeng S,Zhang T,Sun Z,Cao J

Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia.
American journal of human genetics95(1)24-38(2014 Jul)
Simino J,Shi G,Bis JC,Chasman DI,Ehret GB,Gu X,Guo X,Hwang SJ,Sijbrands E,Smith AV,Verwoert GC,Bragg-Gresham JL,Cadby G,Chen P,Cheng CY,Corre T,de Boer RA,Goel A,Johnson T,Khor CC,,Llu?s-Ganella C,Luan J,Lyytik?inen LP,Nolte IM,Sim X,S?ber S,van der Most PJ,Verweij N,Zhao JH,Amin N,Boerwinkle E,Bouchard C,Dehghan A,Eiriksdottir G,Elosua R,Franco OH,Gieger C,Harris TB,Hercberg S,Hofman A,James AL,Johnson AD,K?h?nen M,Khaw KT,Kutalik Z,Larson MG,Launer LJ,Li G,Liu J,Liu K,Morrison AC,Navis G,Ong RT,Papanicolau GJ,Penninx BW,Psaty BM,Raffel LJ,Raitakari OT,Rice K,Rivadeneira F,Rose LM,Sanna S,Scott RA,Siscovick DS,Stolk RP,Uitterlinden AG,Vaidya D,van der Klauw MM,Vasan RS,Vithana EN,V?lker U,V?lzke H,Watkins H,Young TL,Aung T,Bochud M,Farrall M,Hartman CA,Laan M,Lakatta EG,Lehtim?ki T,Loos RJ,Lucas G,Meneton P,Palmer LJ,Rettig R,Snieder H,Tai ES,Teo YY,van der Harst P,Wareham NJ,Wijmenga C,Wong TY,Fornage M,Gudnason V,Levy D,Palmas W,Ridker PM,Rotter JI,van Duijn CM,Witteman JC,Chakravarti A,Rao DC

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GRB14 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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