Gene Symbol | ANGPTL3 |
Entrez Gene ID | 27329 |
Full Name | angiopoietin like 3 |
Synonyms | ANG-5,ANGPT5,ANL3,FHBL2 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metabolism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2. [provided by RefSeq, Aug 2015]. |
Disorder MIM: | |
Disorder Html: | Hypobetalipoproteinemia, familial, 2, 605019 (3) |