ANGPTL3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ANGPTL3
Entrez Gene ID	27329
Full Name	angiopoietin like 3
Synonyms	ANG-5,ANGPT5,ANL3,FHBL2
General protein information	Preferred Names angiopoietin like 3 Names angiopoietin-related protein 3 angiopoietin 5
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p31.3
Summary	This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metabolism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2. [provided by RefSeq, Aug 2015].
Disorder MIM:	604774
Disorder Html:	Hypobetalipoproteinemia, familial, 2, 605019 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_014495.3	NP_055310.1	angiopoietin-related protein 3 preproprotein
NM_014495.4	NP_055310.1	angiopoietin-related protein 3 preproprotein

Pathways from BioSystems

Homologies

Bos taurus (cattle)	ANGPTL3	NP_001073814.1
Gallus gallus (chicken)	ANGPTL3	NP_001128594.1
Danio rerio (zebrafish)	angptl3	NP_571893.1
Mus musculus (house mouse)	Angptl3	NP_038941.1
Pan troglodytes (chimpanzee)	ANGPTL3	XP_001159650.1
	ANGPTL3	XP_001086114.1
Canis lupus familiaris (dog)	ANGPTL3	XP_005620276.1
Homo sapiens (human)	ANGPTL3	NP_055310.1
Rattus norvegicus (Norway rat)	Angptl3	NP_001020236.1
Xenopus tropicalis (tropical clawed frog)	LOC496885	NP_001011408.1

Gene Ontology

The following ANGPTL3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ANGPTL3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu25106	NM_014495.4 Latest version!	Homo sapiens angiopoietin like 3 (ANGPTL3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
View Old Accession Versions >>
OHu25106	NM_014495.3	Homo sapiens angiopoietin like 3 (ANGPTL3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ANGPTL3 ( NM_014495.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_055310.1 Homo sapiens angiopoietin like 3 (ANGPTL3), mRNA.

Price & Availability↑

CloneID	OHu25106
Clone ID Related Accession (Same CDS sequence)	NM_014495.3 , NM_014495.4
Accession Version	NM_014495.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1383bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-22
Organism	Homo sapiens(human)
Product	angiopoietin-related protein 3 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG562798.1, BC007059.1, BC058287.1 and AL138847.14. This sequence is a reference standard in the RefSeqGene project. On Feb 23, 2013 this sequence version replaced NM_014495.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY358273.1, BC058287.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2145122 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTCACAA TTAAGCTCCT TCTTTTTATT GTTCCTCTAG TTATTTCCTC CAGAATTGAT 
CAAGACAATT CATCATTTGA TTCTCTATCT CCAGAGCCAA AATCAAGATT TGCTATGTTA 
GACGATGTAA AAATTTTAGC CAATGGCCTC CTTCAGTTGG GACATGGTCT TAAAGACTTT 
GTCCATAAGA CGAAGGGCCA AATTAATGAC ATATTTCAAA AACTCAACAT ATTTGATCAG 
TCTTTTTATG ATCTATCGCT GCAAACCAGT GAAATCAAAG AAGAAGAAAA GGAACTGAGA 
AGAACTACAT ATAAACTACA AGTCAAAAAT GAAGAGGTAA AGAATATGTC ACTTGAACTC 
AACTCAAAAC TTGAAAGCCT CCTAGAAGAA AAAATTCTAC TTCAACAAAA AGTGAAATAT 
TTAGAAGAGC AACTAACTAA CTTAATTCAA AATCAACCTG AAACTCCAGA ACACCCAGAA 
GTAACTTCAC TTAAAACTTT TGTAGAAAAA CAAGATAATA GCATCAAAGA CCTTCTCCAG 
ACCGTGGAAG ACCAATATAA ACAATTAAAC CAACAGCATA GTCAAATAAA AGAAATAGAA 
AATCAGCTCA GAAGGACTAG TATTCAAGAA CCCACAGAAA TTTCTCTATC TTCCAAGCCA 
AGAGCACCAA GAACTACTCC CTTTCTTCAG TTGAATGAAA TAAGAAATGT AAAACATGAT 
GGCATTCCTG CTGAATGTAC CACCATTTAT AACAGAGGTG AACATACAAG TGGCATGTAT 
GCCATCAGAC CCAGCAACTC TCAAGTTTTT CATGTCTACT GTGATGTTAT ATCAGGTAGT 
CCATGGACAT TAATTCAACA TCGAATAGAT GGATCACAAA ACTTCAATGA AACGTGGGAG 
AACTACAAAT ATGGTTTTGG GAGGCTTGAT GGAGAATTTT GGTTGGGCCT AGAGAAGATA 
TACTCCATAG TGAAGCAATC TAATTATGTT TTACGAATTG AGTTGGAAGA CTGGAAAGAC 
AACAAACATT ATATTGAATA TTCTTTTTAC TTGGGAAATC ACGAAACCAA CTATACGCTA 
CATCTAGTTG CGATTACTGG CAATGTCCCC AATGCAATCC CGGAAAACAA AGATTTGGTG 
TTTTCTACTT GGGATCACAA AGCAAAAGGA CACTTCAACT GTCCAGAGGG TTATTCAGGA 
GGCTGGTGGT GGCATGATGA GTGTGGAGAA AACAACCTAA ATGGTAAATA TAACAAACCA 
AGAGCAAAAT CTAAGCCAGA GAGGAGAAGA GGATTATCTT GGAAGTCTCA AAATGGAAGG 
TTATACTCTA TAAAATCAAC CAAAATGTTG ATCCATCCAA CAGATTCAGA AAGCTTTGAA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055310.1
CDS	81..1463
Translation	MFTIKLLLFIVPLVISSRIDQDNSSFDSLSPEPKSRFAMLDDVKILANGLLQLGHGLKDFVHKTKGQINDIFQKLNIFDQSFYDLSLQTSEIKEEEKELRRTTYKLQVKNEEVKNMSLELNSKLESLLEEKILLQQKVKYLEEQLTNLIQNQPETPEHPEVTSLKTFVEKQDNSIKDLLQTVEDQYKQLNQQHSQIKEIENQLRRTSIQEPTEISLSSKPRAPRTTPFLQLNEIRNVKHDGIPAECTTIYNRGEHTSGMYAIRPSNSQVFHVYCDVISGSPWTLIQHRIDGSQNFNETWENYKYGFGRLDGEFWLGLEKIYSIVKQSNYVLRIELEDWKDNKHYIEYSFYLGNHETNYTLHLVAITGNVPNAIPENKDLVFSTWDHKAKGHFNCPEGYSGGWWWHDECGENNLNGKYNKPRAKSKPERRRGLSWKSQNGRLYSIKSTKMLIHPTDSESFE

Target ORF information:

RefSeq Version	NM_014495.3
Organism	Homo sapiens(human)
Definition	Homo sapiens angiopoietin like 3 (ANGPTL3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014495.3

ORF Insert Sequence:

ATGTTCACAA TTAAGCTCCT TCTTTTTATT GTTCCTCTAG TTATTTCCTC CAGAATTGAT 
CAAGACAATT CATCATTTGA TTCTCTATCT CCAGAGCCAA AATCAAGATT TGCTATGTTA 
GACGATGTAA AAATTTTAGC CAATGGCCTC CTTCAGTTGG GACATGGTCT TAAAGACTTT 
GTCCATAAGA CGAAGGGCCA AATTAATGAC ATATTTCAAA AACTCAACAT ATTTGATCAG 
TCTTTTTATG ATCTATCGCT GCAAACCAGT GAAATCAAAG AAGAAGAAAA GGAACTGAGA 
AGAACTACAT ATAAACTACA AGTCAAAAAT GAAGAGGTAA AGAATATGTC ACTTGAACTC 
AACTCAAAAC TTGAAAGCCT CCTAGAAGAA AAAATTCTAC TTCAACAAAA AGTGAAATAT 
TTAGAAGAGC AACTAACTAA CTTAATTCAA AATCAACCTG AAACTCCAGA ACACCCAGAA 
GTAACTTCAC TTAAAACTTT TGTAGAAAAA CAAGATAATA GCATCAAAGA CCTTCTCCAG 
ACCGTGGAAG ACCAATATAA ACAATTAAAC CAACAGCATA GTCAAATAAA AGAAATAGAA 
AATCAGCTCA GAAGGACTAG TATTCAAGAA CCCACAGAAA TTTCTCTATC TTCCAAGCCA 
AGAGCACCAA GAACTACTCC CTTTCTTCAG TTGAATGAAA TAAGAAATGT AAAACATGAT 
GGCATTCCTG CTGAATGTAC CACCATTTAT AACAGAGGTG AACATACAAG TGGCATGTAT 
GCCATCAGAC CCAGCAACTC TCAAGTTTTT CATGTCTACT GTGATGTTAT ATCAGGTAGT 
CCATGGACAT TAATTCAACA TCGAATAGAT GGATCACAAA ACTTCAATGA AACGTGGGAG 
AACTACAAAT ATGGTTTTGG GAGGCTTGAT GGAGAATTTT GGTTGGGCCT AGAGAAGATA 
TACTCCATAG TGAAGCAATC TAATTATGTT TTACGAATTG AGTTGGAAGA CTGGAAAGAC 
AACAAACATT ATATTGAATA TTCTTTTTAC TTGGGAAATC ACGAAACCAA CTATACGCTA 
CATCTAGTTG CGATTACTGG CAATGTCCCC AATGCAATCC CGGAAAACAA AGATTTGGTG 
TTTTCTACTT GGGATCACAA AGCAAAAGGA CACTTCAACT GTCCAGAGGG TTATTCAGGA 
GGCTGGTGGT GGCATGATGA GTGTGGAGAA AACAACCTAA ATGGTAAATA TAACAAACCA 
AGAGCAAAAT CTAAGCCAGA GAGGAGAAGA GGATTATCTT GGAAGTCTCA AAATGGAAGG 
TTATACTCTA TAAAATCAAC CAAAATGTTG ATCCATCCAA CAGATTCAGA AAGCTTTGAA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ANGPTL3 ( NM_014495.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_055310.1 Homo sapiens angiopoietin like 3 (ANGPTL3), mRNA.

Price & Availability↑

CloneID	OHu25106
Clone ID Related Accession (Same CDS sequence)	NM_014495.3 , NM_014495.4
Accession Version	NM_014495.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1383bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-25
Organism	Homo sapiens(human)
Product	angiopoietin-related protein 3 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC007059.1, BC058287.1 and AL138847.14. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_014495.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC058287.1, AK289426.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2145122 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000371129.4/ ENSP00000360170.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTTCACAA TTAAGCTCCT TCTTTTTATT GTTCCTCTAG TTATTTCCTC CAGAATTGAT 
CAAGACAATT CATCATTTGA TTCTCTATCT CCAGAGCCAA AATCAAGATT TGCTATGTTA 
GACGATGTAA AAATTTTAGC CAATGGCCTC CTTCAGTTGG GACATGGTCT TAAAGACTTT 
GTCCATAAGA CGAAGGGCCA AATTAATGAC ATATTTCAAA AACTCAACAT ATTTGATCAG 
TCTTTTTATG ATCTATCGCT GCAAACCAGT GAAATCAAAG AAGAAGAAAA GGAACTGAGA 
AGAACTACAT ATAAACTACA AGTCAAAAAT GAAGAGGTAA AGAATATGTC ACTTGAACTC 
AACTCAAAAC TTGAAAGCCT CCTAGAAGAA AAAATTCTAC TTCAACAAAA AGTGAAATAT 
TTAGAAGAGC AACTAACTAA CTTAATTCAA AATCAACCTG AAACTCCAGA ACACCCAGAA 
GTAACTTCAC TTAAAACTTT TGTAGAAAAA CAAGATAATA GCATCAAAGA CCTTCTCCAG 
ACCGTGGAAG ACCAATATAA ACAATTAAAC CAACAGCATA GTCAAATAAA AGAAATAGAA 
AATCAGCTCA GAAGGACTAG TATTCAAGAA CCCACAGAAA TTTCTCTATC TTCCAAGCCA 
AGAGCACCAA GAACTACTCC CTTTCTTCAG TTGAATGAAA TAAGAAATGT AAAACATGAT 
GGCATTCCTG CTGAATGTAC CACCATTTAT AACAGAGGTG AACATACAAG TGGCATGTAT 
GCCATCAGAC CCAGCAACTC TCAAGTTTTT CATGTCTACT GTGATGTTAT ATCAGGTAGT 
CCATGGACAT TAATTCAACA TCGAATAGAT GGATCACAAA ACTTCAATGA AACGTGGGAG 
AACTACAAAT ATGGTTTTGG GAGGCTTGAT GGAGAATTTT GGTTGGGCCT AGAGAAGATA 
TACTCCATAG TGAAGCAATC TAATTATGTT TTACGAATTG AGTTGGAAGA CTGGAAAGAC 
AACAAACATT ATATTGAATA TTCTTTTTAC TTGGGAAATC ACGAAACCAA CTATACGCTA 
CATCTAGTTG CGATTACTGG CAATGTCCCC AATGCAATCC CGGAAAACAA AGATTTGGTG 
TTTTCTACTT GGGATCACAA AGCAAAAGGA CACTTCAACT GTCCAGAGGG TTATTCAGGA 
GGCTGGTGGT GGCATGATGA GTGTGGAGAA AACAACCTAA ATGGTAAATA TAACAAACCA 
AGAGCAAAAT CTAAGCCAGA GAGGAGAAGA GGATTATCTT GGAAGTCTCA AAATGGAAGG 
TTATACTCTA TAAAATCAAC CAAAATGTTG ATCCATCCAA CAGATTCAGA AAGCTTTGAA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055310.1
CDS	48..1430
Translation	MFTIKLLLFIVPLVISSRIDQDNSSFDSLSPEPKSRFAMLDDVKILANGLLQLGHGLKDFVHKTKGQINDIFQKLNIFDQSFYDLSLQTSEIKEEEKELRRTTYKLQVKNEEVKNMSLELNSKLESLLEEKILLQQKVKYLEEQLTNLIQNQPETPEHPEVTSLKTFVEKQDNSIKDLLQTVEDQYKQLNQQHSQIKEIENQLRRTSIQEPTEISLSSKPRAPRTTPFLQLNEIRNVKHDGIPAECTTIYNRGEHTSGMYAIRPSNSQVFHVYCDVISGSPWTLIQHRIDGSQNFNETWENYKYGFGRLDGEFWLGLEKIYSIVKQSNYVLRIELEDWKDNKHYIEYSFYLGNHETNYTLHLVAITGNVPNAIPENKDLVFSTWDHKAKGHFNCPEGYSGGWWWHDECGENNLNGKYNKPRAKSKPERRRGLSWKSQNGRLYSIKSTKMLIHPTDSESFE

Target ORF information:

RefSeq Version	NM_014495.4
Organism	Homo sapiens(human)
Definition	Homo sapiens angiopoietin like 3 (ANGPTL3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014495.4

ORF Insert Sequence:

ATGTTCACAA TTAAGCTCCT TCTTTTTATT GTTCCTCTAG TTATTTCCTC CAGAATTGAT 
CAAGACAATT CATCATTTGA TTCTCTATCT CCAGAGCCAA AATCAAGATT TGCTATGTTA 
GACGATGTAA AAATTTTAGC CAATGGCCTC CTTCAGTTGG GACATGGTCT TAAAGACTTT 
GTCCATAAGA CGAAGGGCCA AATTAATGAC ATATTTCAAA AACTCAACAT ATTTGATCAG 
TCTTTTTATG ATCTATCGCT GCAAACCAGT GAAATCAAAG AAGAAGAAAA GGAACTGAGA 
AGAACTACAT ATAAACTACA AGTCAAAAAT GAAGAGGTAA AGAATATGTC ACTTGAACTC 
AACTCAAAAC TTGAAAGCCT CCTAGAAGAA AAAATTCTAC TTCAACAAAA AGTGAAATAT 
TTAGAAGAGC AACTAACTAA CTTAATTCAA AATCAACCTG AAACTCCAGA ACACCCAGAA 
GTAACTTCAC TTAAAACTTT TGTAGAAAAA CAAGATAATA GCATCAAAGA CCTTCTCCAG 
ACCGTGGAAG ACCAATATAA ACAATTAAAC CAACAGCATA GTCAAATAAA AGAAATAGAA 
AATCAGCTCA GAAGGACTAG TATTCAAGAA CCCACAGAAA TTTCTCTATC TTCCAAGCCA 
AGAGCACCAA GAACTACTCC CTTTCTTCAG TTGAATGAAA TAAGAAATGT AAAACATGAT 
GGCATTCCTG CTGAATGTAC CACCATTTAT AACAGAGGTG AACATACAAG TGGCATGTAT 
GCCATCAGAC CCAGCAACTC TCAAGTTTTT CATGTCTACT GTGATGTTAT ATCAGGTAGT 
CCATGGACAT TAATTCAACA TCGAATAGAT GGATCACAAA ACTTCAATGA AACGTGGGAG 
AACTACAAAT ATGGTTTTGG GAGGCTTGAT GGAGAATTTT GGTTGGGCCT AGAGAAGATA 
TACTCCATAG TGAAGCAATC TAATTATGTT TTACGAATTG AGTTGGAAGA CTGGAAAGAC 
AACAAACATT ATATTGAATA TTCTTTTTAC TTGGGAAATC ACGAAACCAA CTATACGCTA 
CATCTAGTTG CGATTACTGG CAATGTCCCC AATGCAATCC CGGAAAACAA AGATTTGGTG 
TTTTCTACTT GGGATCACAA AGCAAAAGGA CACTTCAACT GTCCAGAGGG TTATTCAGGA 
GGCTGGTGGT GGCATGATGA GTGTGGAGAA AACAACCTAA ATGGTAAATA TAACAAACCA 
AGAGCAAAAT CTAAGCCAGA GAGGAGAAGA GGATTATCTT GGAAGTCTCA AAATGGAAGG 
TTATACTCTA TAAAATCAAC CAAAATGTTG ATCCATCCAA CAGATTCAGA AAGCTTTGAA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

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ANGPTL3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

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