ARHGEF16 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ARHGEF16
Entrez Gene ID	27237
Full Name	Rho guanine nucleotide exchange factor 16
Synonyms	GEF16,NBR
General protein information	Preferred Names Rho guanine nucleotide exchange factor 16 Names rho guanine nucleotide exchange factor 16 Rho guanine exchange factor (GEF) 16 Rho guanine nucleotide exchange factor (GEF) 16 ephexin-4
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p36.32
Summary	Although the specific function of this protein is not known yet, it is thought to be involved in protein-protein and protein-lipid interactions. [provided by RefSeq, Jul 2008].

mRNA and Protein(s)

mRNA	Protein	Name
NM_014448.4	NP_055263.2	rho guanine nucleotide exchange factor 16
XM_017001049.1	XP_016856538.1	rho guanine nucleotide exchange factor 16 isoform X1
XM_017001050.1	XP_016856539.1	rho guanine nucleotide exchange factor 16 isoform X2
NM_014448.3	NP_055263.2	rho guanine nucleotide exchange factor 16
XM_017001051.1	XP_016856540.1	rho guanine nucleotide exchange factor 16 isoform X2
XM_024446454.1	XP_024302222.1	rho guanine nucleotide exchange factor 16 isoform X3
XM_024446455.1	XP_024302223.1	rho guanine nucleotide exchange factor 16 isoform X3

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Arhgef16	NP_001121063.1
Pan troglodytes (chimpanzee)	ARHGEF16	XP_001159969.3
Canis lupus familiaris (dog)	ARHGEF16	XP_005620490.1
	ARHGEF16	XP_001082733.1
Mus musculus (house mouse)	Arhgef16	NP_001106215.1
Homo sapiens (human)	ARHGEF16	NP_055263.2
Gallus gallus (chicken)	ARHGEF16	XP_417549.4
Danio rerio (zebrafish)	arhgef16	NP_001116755.1
Bos taurus (cattle)	ARHGEF16	NP_001095468.1
Caenorhabditis elegans (roundworm)	tag-218	NP_494706.1

Gene Ontology
Bibliography

Related articles in PubMed

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
Guo Z, Neilson LJ, Zhong H, Murray PS, Zanivan S, Zaidel-Bar R
Science signaling7(354)rs7(2014 Dec)

The HPV16 E6 binding protein Tip-1 interacts with ARHGEF16, which activates Cdc42.
Oliver AW, He X, Borthwick K, Donne AJ, Hampson L, Hampson IN
British journal of cancer104(2)324-31(2011 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These data suggest that HPV16 E6, Tip-1 and ARHGEF16 may cooperate to activate Cdc42 and support a potential link between the expression of HPV16 E6 and Cdc42 activation
Title: The HPV16 E6 binding protein Tip-1 interacts with ARHGEF16, which activates Cdc42.

The ephexin4 protein mediates cell migration through a RhoG-dependent mechanism.
Title: Ephexin4 and EphA2 mediate cell migration through a RhoG-dependent mechanism.

Observational study of gene-disease association. (HuGE Navigator)
Title: Mutation of ARHGAP9 in patients with coronary spastic angina.

Sixty-four novel structural analogues of Y27632 were synthesized and tested for their ability to persistently inhibit the transformation of NIH3T3 cells by Rho guanidine exchange factor 16 (ARHGEF16) or Ras.
Title: Analogues of Y27632 increase gap junction communication and suppress the formation of transformed NIH3T3 colonies.

The following ARHGEF16 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ARHGEF16 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu06388	NM_014448.3 Latest version!	Homo sapiens Rho guanine nucleotide exchange factor 16 (ARHGEF16), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu104371	XM_024446454.1 Latest version!	Homo sapiens Rho guanine nucleotide exchange factor 16 (ARHGEF16), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu104371	XM_024446455.1 Latest version!	Homo sapiens Rho guanine nucleotide exchange factor 16 (ARHGEF16), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu87258	NM_014448.4 Latest version!	Homo sapiens Rho guanine nucleotide exchange factor 16 (ARHGEF16), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OHu87257	XM_017001049.1 Latest version!	Homo sapiens Rho guanine nucleotide exchange factor 16 (ARHGEF16), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OHu87258	XM_017001050.1 Latest version!	Homo sapiens Rho guanine nucleotide exchange factor 16 (ARHGEF16), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OHu87258	XM_017001051.1 Latest version!	Homo sapiens Rho guanine nucleotide exchange factor 16 (ARHGEF16), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ARHGEF16 ( NM_014448.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_055263.2 Homo sapiens Rho guanine nucleotide exchange factor 16 (ARHGEF16), mRNA.

Price & Availability↑

CloneID	OHu06388
Clone ID Related Accession (Same CDS sequence)	NM_014448.3
Accession Version	NM_014448.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2130bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-26
Organism	Homo sapiens(human)
Product	rho guanine nucleotide exchange factor 16
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB499586.1, AK095984.1, DA539376.1, BC002681.1 and BC051838.1. On Dec 20, 2007 this sequence version replaced NM_014448.2. ##Evidence-Data-START## Transcript exon combination :: AK095984.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCCAGC GGCACTCAGA CAGCTCCTTG GAGGAGAAGC TCCTGGGACA CCGCTTCCAC 
TCGGAGCTCC GGCTCGATGC CGGGGGGAAC CCAGCCTCCG GGCTCCCAAT GGTCCGTGGC 
TCCCCGCGTG TTAGAGACGA TGCCGCCTTC CAGCCCCAGG TCCCGGCACC CCCACAGCCT 
CGGCCCCCGG GGCACGAGGA GCCATGGCCC ATCGTCCTGA GCACAGAGAG CCCGGCGGCC 
CTCAAGCTGG GCACCCAACA GCTGATCCCT AAGAGCCTGG CTGTGGCCAG CAAGGCAAAG 
ACCCCAGCCC GCCACCAGAG CTTCGGGGCG GCTGTACTTA GCAGGGAGGC CGCCCGGCGG 
GACCCTAAGC TCCTCCCAGC CCCCAGCTTC TCCCTGGATG ACATGGACGT GGACAAGGAC 
CCCGGGGGCA TGCTGAGGCG GAACCTGCGG AACCAATCCT ACCGGGCGGC CATGAAGGGC 
CTGGGGAAGC CAGGTGGCCA GGGAGATGCC ATCCAGCTAA GCCCTAAGCT CCAGGCTCTG 
GCTGAGGAAC CCAGCCAGCC TCATACTCGG AGCCCGGCCA AAAACAAGAA GACGCTGGGG 
AGGAAACGTG GGCACAAGGG TTCCTTCAAG GACGACCCCC AGCTCTACCA GGAGATCCAG 
GAGCGGGGCC TGAACACCAG CCAGGAGTCT GATGACGACA TCCTCGATGA GTCCTCCAGC 
CCCGAGGGAA CCCAGAAGGT GGACGCCACC ATTGTGGTCA AGAGCTACCG GCCCGCCCAG 
GTCACCTGGA GCCAGCTCCC AGAGGTGGTG GAATTGGGCA TCCTGGACCA GCTCTCCACT 
GAGGAGCGGA AAAGGCAGGA GGCCATGTTC GAGATCCTCA CGTCGGAGTT CTCCTACCAG 
CACAGCCTGA GCATCCTGGT GGAGGAGTTC CTGCAGTCCA AGGAGCTGCG GGCGACCGTG 
ACCCAGATGG AGCACCACCA CCTCTTCTCC AACATCCTGG ATGTCCTGGG TGCCAGTCAG 
AGGTTCTTCG AGGACCTGGA GCAGCGGCAC AAGGCCCAGG TGCTGGTCGA GGACATCAGT 
GACATCCTGG AGGAGCACGC TGAGAAGCAC TTCCACCCCT ACATCGCCTA CTGCTCCAAC 
GAGGTCTACC AACAGCGCAC GCTGCAGAAG CTGATAAGCA GCAACGCCGC CTTCCGAGAG 
GCCCTGAGAG AGATTGAGAG GCGGCCGGCG TGCGGGGGCC TGCCCATGCT CTCCTTCCTG 
ATCCTCCCCA TGCAGCGGGT GACCCGGCTG CCCCTCCTGA TGGATACGCT CTGCCTCAAG 
ACCCAGGGCC ACTCCGAAAG GTACAAGGCT GCCAGCCGTG CACTGAAGGC CATCAGCAAG 
CTGGTGAGGC AGTGCAACGA GGGGGCCCAC AGGATGGAGC GCATGGAGCA GATGTACACG 
CTGCACACAC AGCTGGACTT CAGCAAGGTC AAGTCCCTCC CACTGATCTC CGCCTCCCGG 
TGGCTGCTGA AGCGCGGAGA GCTGTTCTTA GTGGAAGAAA CCGGACTTTT TCGAAAAATT 
GCCAGCCGGC CAACGTGCTA CCTTTTCCTG TTCAACGATG TCCTGGTTGT GACCAAGAAG 
AAGAGCGAGG AGAGCTACAT GGTCCAGGAC TACGCCCAGA TGAACCACAT CCAGGTGGAG 
AAGATAGAGC CGTCTGAGCT CCCTCTGCCC GGGGGCGGCA ACCGTAGCTC CTCCGTGCCC 
CACCCCTTCC AGGTGACCCT GCTTCGCAAC AGCGAGGGCC GCCAGGAGCA GCTCCTGCTC 
TCCTCGGACT CCGCGAGTGA CCGGGCACGG TGGATCGTGG CGCTCACACA CAGTGAGAGA 
CAGTGGCAGG GCCTCTCCAG CAAAGGAGAC CTGCCCCAGG TGGAGATCAC CAAGGCCTTC 
TTCGCGAAGC AAGCAGACGA GGTCACACTG CAGCAGGCGG ACGTGGTCCT GGTTCTGCAG 
CAGGAGGATG GGTGGCTCTA TGGCGAGAGG CTCCGGGACG GAGAGACGGG ATGGTTCCCC 
GAGGACTTTG CCCGCTTCAT CACCAGCCGT GTGGCCGTGG AGGGCAATGT CCGCAGGATG 
GAGCGTCTGC GGGTGGAGAC GGACGTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055263.2
CDS	249..2378
Translation	MAQRHSDSSLEEKLLGHRFHSELRLDAGGNPASGLPMVRGSPRVRDDAAFQPQVPAPPQPRPPGHEEPWPIVLSTESPAALKLGTQQLIPKSLAVASKAKTPARHQSFGAAVLSREAARRDPKLLPAPSFSLDDMDVDKDPGGMLRRNLRNQSYRAAMKGLGKPGGQGDAIQLSPKLQALAEEPSQPHTRSPAKNKKTLGRKRGHKGSFKDDPQLYQEIQERGLNTSQESDDDILDESSSPEGTQKVDATIVVKSYRPAQVTWSQLPEVVELGILDQLSTEERKRQEAMFEILTSEFSYQHSLSILVEEFLQSKELRATVTQMEHHHLFSNILDVLGASQRFFEDLEQRHKAQVLVEDISDILEEHAEKHFHPYIAYCSNEVYQQRTLQKLISSNAAFREALREIERRPACGGLPMLSFLILPMQRVTRLPLLMDTLCLKTQGHSERYKAASRALKAISKLVRQCNEGAHRMERMEQMYTLHTQLDFSKVKSLPLISASRWLLKRGELFLVEETGLFRKIASRPTCYLFLFNDVLVVTKKKSEESYMVQDYAQMNHIQVEKIEPSELPLPGGGNRSSSVPHPFQVTLLRNSEGRQEQLLLSSDSASDRARWIVALTHSERQWQGLSSKGDLPQVEITKAFFAKQADEVTLQQADVVLVLQQEDGWLYGERLRDGETGWFPEDFARFITSRVAVEGNVRRMERLRVETDV

Target ORF information:

RefSeq Version	NM_014448.3
Organism	Homo sapiens(human)
Definition	Homo sapiens Rho guanine nucleotide exchange factor 16 (ARHGEF16), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014448.3

ORF Insert Sequence:

ATGGCCCAGC GGCACTCAGA CAGCTCCTTG GAGGAGAAGC TCCTGGGACA CCGCTTCCAC 
TCGGAGCTCC GGCTCGATGC CGGGGGGAAC CCAGCCTCCG GGCTCCCAAT GGTCCGTGGC 
TCCCCGCGTG TTAGAGACGA TGCCGCCTTC CAGCCCCAGG TCCCGGCACC CCCACAGCCT 
CGGCCCCCGG GGCACGAGGA GCCATGGCCC ATCGTCCTGA GCACAGAGAG CCCGGCGGCC 
CTCAAGCTGG GCACCCAACA GCTGATCCCT AAGAGCCTGG CTGTGGCCAG CAAGGCAAAG 
ACCCCAGCCC GCCACCAGAG CTTCGGGGCG GCTGTACTTA GCAGGGAGGC CGCCCGGCGG 
GACCCTAAGC TCCTCCCAGC CCCCAGCTTC TCCCTGGATG ACATGGACGT GGACAAGGAC 
CCCGGGGGCA TGCTGAGGCG GAACCTGCGG AACCAATCCT ACCGGGCGGC CATGAAGGGC 
CTGGGGAAGC CAGGTGGCCA GGGAGATGCC ATCCAGCTAA GCCCTAAGCT CCAGGCTCTG 
GCTGAGGAAC CCAGCCAGCC TCATACTCGG AGCCCGGCCA AAAACAAGAA GACGCTGGGG 
AGGAAACGTG GGCACAAGGG TTCCTTCAAG GACGACCCCC AGCTCTACCA GGAGATCCAG 
GAGCGGGGCC TGAACACCAG CCAGGAGTCT GATGACGACA TCCTCGATGA GTCCTCCAGC 
CCCGAGGGAA CCCAGAAGGT GGACGCCACC ATTGTGGTCA AGAGCTACCG GCCCGCCCAG 
GTCACCTGGA GCCAGCTCCC AGAGGTGGTG GAATTGGGCA TCCTGGACCA GCTCTCCACT 
GAGGAGCGGA AAAGGCAGGA GGCCATGTTC GAGATCCTCA CGTCGGAGTT CTCCTACCAG 
CACAGCCTGA GCATCCTGGT GGAGGAGTTC CTGCAGTCCA AGGAGCTGCG GGCGACCGTG 
ACCCAGATGG AGCACCACCA CCTCTTCTCC AACATCCTGG ATGTCCTGGG TGCCAGTCAG 
AGGTTCTTCG AGGACCTGGA GCAGCGGCAC AAGGCCCAGG TGCTGGTCGA GGACATCAGT 
GACATCCTGG AGGAGCACGC TGAGAAGCAC TTCCACCCCT ACATCGCCTA CTGCTCCAAC 
GAGGTCTACC AACAGCGCAC GCTGCAGAAG CTGATAAGCA GCAACGCCGC CTTCCGAGAG 
GCCCTGAGAG AGATTGAGAG GCGGCCGGCG TGCGGGGGCC TGCCCATGCT CTCCTTCCTG 
ATCCTCCCCA TGCAGCGGGT GACCCGGCTG CCCCTCCTGA TGGATACGCT CTGCCTCAAG 
ACCCAGGGCC ACTCCGAAAG GTACAAGGCT GCCAGCCGTG CACTGAAGGC CATCAGCAAG 
CTGGTGAGGC AGTGCAACGA GGGGGCCCAC AGGATGGAGC GCATGGAGCA GATGTACACG 
CTGCACACAC AGCTGGACTT CAGCAAGGTC AAGTCCCTCC CACTGATCTC CGCCTCCCGG 
TGGCTGCTGA AGCGCGGAGA GCTGTTCTTA GTGGAAGAAA CCGGACTTTT TCGAAAAATT 
GCCAGCCGGC CAACGTGCTA CCTTTTCCTG TTCAACGATG TCCTGGTTGT GACCAAGAAG 
AAGAGCGAGG AGAGCTACAT GGTCCAGGAC TACGCCCAGA TGAACCACAT CCAGGTGGAG 
AAGATAGAGC CGTCTGAGCT CCCTCTGCCC GGGGGCGGCA ACCGTAGCTC CTCCGTGCCC 
CACCCCTTCC AGGTGACCCT GCTTCGCAAC AGCGAGGGCC GCCAGGAGCA GCTCCTGCTC 
TCCTCGGACT CCGCGAGTGA CCGGGCACGG TGGATCGTGG CGCTCACACA CAGTGAGAGA 
CAGTGGCAGG GCCTCTCCAG CAAAGGAGAC CTGCCCCAGG TGGAGATCAC CAAGGCCTTC 
TTCGCGAAGC AAGCAGACGA GGTCACACTG CAGCAGGCGG ACGTGGTCCT GGTTCTGCAG 
CAGGAGGATG GGTGGCTCTA TGGCGAGAGG CTCCGGGACG GAGAGACGGG ATGGTTCCCC 
GAGGACTTTG CCCGCTTCAT CACCAGCCGT GTGGCCGTGG AGGGCAATGT CCGCAGGATG 
GAGCGTCTGC GGGTGGAGAC GGACGTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ARHGEF16 ( XM_024446454.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024302222.1 Homo sapiens Rho guanine nucleotide exchange factor 16 (ARHGEF16), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu104371
Clone ID Related Accession (Same CDS sequence)	XM_024446454.1 , XM_024446455.1
Accession Version	XM_024446454.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1266bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	rho guanine nucleotide exchange factor 16 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTCGAGA TCCTCACGTC GGAGTTCTCC TACCAGCACA GCCTGAGCAT CCTGGTGGAG 
GAGTTCCTGC AGTCCAAGGA GCTGCGGGCG ACCGTGACCC AGATGGAGCA CCACCACCTC 
TTCTCCAACA TCCTGGATGT CCTGGGTGCC AGTCAGAGGT TCTTCGAGGA CCTGGAGCAG 
CGGCACAAGG CCCAGGTGCT GGTCGAGGAC ATCAGTGACA TCCTGGAGGA GCACGCTGAG 
AAGCACTTCC ACCCCTACAT CGCCTACTGC TCCAACGAGG TCTACCAACA GCGCACGCTG 
CAGAAGCTGA TAAGCAGCAA CGCCGCCTTC CGAGAGGCCC TGAGAGAGAT TGAGAGGCGG 
CCGGCGTGCG GGGGCCTGCC CATGCTCTCC TTCCTGATCC TCCCCATGCA GCGGGTGACC 
CGGCTGCCCC TCCTGATGGA TACGCTCTGC CTCAAGACCC AGGGCCACTC CGAAAGGTAC 
AAGGCTGCCA GCCGTGCACT GAAGGCCATC AGCAAGCTGG TGAGGCAGTG CAACGAGGGG 
GCCCACAGGA TGGAGCGCAT GGAGCAGATG TACACGCTGC ACACACAGCT GGACTTCAGC 
AAGGTCAAGT CCCTCCCACT GATCTCTGCC TCCCGGTGGC TGCTGAAGCG CGGAGAGCTG 
TTCTTAGTGG AAGAAACCGG ACTTTTTCGA AAAATTGCCA GCCGGCCAAC GTGCTACCTT 
TTCCTGTTCA ACGATGTCCT GGTTGTGACC AAGAAGAAGA GCGAGGAGAG CTACATGGTC 
CAGGACTACG CCCAGATGAA CCACATCCAG GTGGAGAAGA TAGAGCCGTC TGAGCTCCCT 
CTGCCCGGGG GCGGCAACCG TAGCTCCTCC GTGCCCCACC CCTTCCAGGT GACCCTGCTT 
CGCAACAGCG AGGGCCGCCA GGAGCAGCTC CTGCTCTCCT CGGACTCCGC GAGTGACCGG 
GCACGGTGGA TCGTGGCGCT CACACACAGT GAGAGACAGT GGCAGGGCCT CTCCAGCAAA 
GGAGACCTGC CCCAGGTGGA GATCACCAAG GCCTTCTTCG CGAAGCAAGC AGACGAGGTC 
ACACTGCAGC AGGCGGACGT GGTCCTGGTT CTGCAGCAGG AGGATGGGTG GCTCTATGGC 
GAGAGGCTCC GGGACGGAGA GACGGGATGG TTCCCCGAGG ACTTTGCCCG CTTCATCACC 
AGCCGTGTGG CCGTGGAGGG CAATGTCCGC AGGATGGAGC GTCTGCGGGT GGAGACGGAC 
GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024302222.1
CDS	390..1655
Translation	MFEILTSEFSYQHSLSILVEEFLQSKELRATVTQMEHHHLFSNILDVLGASQRFFEDLEQRHKAQVLVEDISDILEEHAEKHFHPYIAYCSNEVYQQRTLQKLISSNAAFREALREIERRPACGGLPMLSFLILPMQRVTRLPLLMDTLCLKTQGHSERYKAASRALKAISKLVRQCNEGAHRMERMEQMYTLHTQLDFSKVKSLPLISASRWLLKRGELFLVEETGLFRKIASRPTCYLFLFNDVLVVTKKKSEESYMVQDYAQMNHIQVEKIEPSELPLPGGGNRSSSVPHPFQVTLLRNSEGRQEQLLLSSDSASDRARWIVALTHSERQWQGLSSKGDLPQVEITKAFFAKQADEVTLQQADVVLVLQQEDGWLYGERLRDGETGWFPEDFARFITSRVAVEGNVRRMERLRVETDV

Target ORF information:

RefSeq Version	XM_024446454.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rho guanine nucleotide exchange factor 16 (ARHGEF16), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024446454.1

ORF Insert Sequence:

ATGTTCGAGA TCCTCACGTC GGAGTTCTCC TACCAGCACA GCCTGAGCAT CCTGGTGGAG 
GAGTTCCTGC AGTCCAAGGA GCTGCGGGCG ACCGTGACCC AGATGGAGCA CCACCACCTC 
TTCTCCAACA TCCTGGATGT CCTGGGTGCC AGTCAGAGGT TCTTCGAGGA CCTGGAGCAG 
CGGCACAAGG CCCAGGTGCT GGTCGAGGAC ATCAGTGACA TCCTGGAGGA GCACGCTGAG 
AAGCACTTCC ACCCCTACAT CGCCTACTGC TCCAACGAGG TCTACCAACA GCGCACGCTG 
CAGAAGCTGA TAAGCAGCAA CGCCGCCTTC CGAGAGGCCC TGAGAGAGAT TGAGAGGCGG 
CCGGCGTGCG GGGGCCTGCC CATGCTCTCC TTCCTGATCC TCCCCATGCA GCGGGTGACC 
CGGCTGCCCC TCCTGATGGA TACGCTCTGC CTCAAGACCC AGGGCCACTC CGAAAGGTAC 
AAGGCTGCCA GCCGTGCACT GAAGGCCATC AGCAAGCTGG TGAGGCAGTG CAACGAGGGG 
GCCCACAGGA TGGAGCGCAT GGAGCAGATG TACACGCTGC ACACACAGCT GGACTTCAGC 
AAGGTCAAGT CCCTCCCACT GATCTCTGCC TCCCGGTGGC TGCTGAAGCG CGGAGAGCTG 
TTCTTAGTGG AAGAAACCGG ACTTTTTCGA AAAATTGCCA GCCGGCCAAC GTGCTACCTT 
TTCCTGTTCA ACGATGTCCT GGTTGTGACC AAGAAGAAGA GCGAGGAGAG CTACATGGTC 
CAGGACTACG CCCAGATGAA CCACATCCAG GTGGAGAAGA TAGAGCCGTC TGAGCTCCCT 
CTGCCCGGGG GCGGCAACCG TAGCTCCTCC GTGCCCCACC CCTTCCAGGT GACCCTGCTT 
CGCAACAGCG AGGGCCGCCA GGAGCAGCTC CTGCTCTCCT CGGACTCCGC GAGTGACCGG 
GCACGGTGGA TCGTGGCGCT CACACACAGT GAGAGACAGT GGCAGGGCCT CTCCAGCAAA 
GGAGACCTGC CCCAGGTGGA GATCACCAAG GCCTTCTTCG CGAAGCAAGC AGACGAGGTC 
ACACTGCAGC AGGCGGACGT GGTCCTGGTT CTGCAGCAGG AGGATGGGTG GCTCTATGGC 
GAGAGGCTCC GGGACGGAGA GACGGGATGG TTCCCCGAGG ACTTTGCCCG CTTCATCACC 
AGCCGTGTGG CCGTGGAGGG CAATGTCCGC AGGATGGAGC GTCTGCGGGT GGAGACGGAC 
GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ARHGEF16 ( XM_024446455.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024302223.1 Homo sapiens Rho guanine nucleotide exchange factor 16 (ARHGEF16), transcript variant X5, mRNA.

Price & Availability↑

CloneID	OHu104371
Clone ID Related Accession (Same CDS sequence)	XM_024446454.1 , XM_024446455.1
Accession Version	XM_024446455.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1266bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	rho guanine nucleotide exchange factor 16 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTCGAGA TCCTCACGTC GGAGTTCTCC TACCAGCACA GCCTGAGCAT CCTGGTGGAG 
GAGTTCCTGC AGTCCAAGGA GCTGCGGGCG ACCGTGACCC AGATGGAGCA CCACCACCTC 
TTCTCCAACA TCCTGGATGT CCTGGGTGCC AGTCAGAGGT TCTTCGAGGA CCTGGAGCAG 
CGGCACAAGG CCCAGGTGCT GGTCGAGGAC ATCAGTGACA TCCTGGAGGA GCACGCTGAG 
AAGCACTTCC ACCCCTACAT CGCCTACTGC TCCAACGAGG TCTACCAACA GCGCACGCTG 
CAGAAGCTGA TAAGCAGCAA CGCCGCCTTC CGAGAGGCCC TGAGAGAGAT TGAGAGGCGG 
CCGGCGTGCG GGGGCCTGCC CATGCTCTCC TTCCTGATCC TCCCCATGCA GCGGGTGACC 
CGGCTGCCCC TCCTGATGGA TACGCTCTGC CTCAAGACCC AGGGCCACTC CGAAAGGTAC 
AAGGCTGCCA GCCGTGCACT GAAGGCCATC AGCAAGCTGG TGAGGCAGTG CAACGAGGGG 
GCCCACAGGA TGGAGCGCAT GGAGCAGATG TACACGCTGC ACACACAGCT GGACTTCAGC 
AAGGTCAAGT CCCTCCCACT GATCTCTGCC TCCCGGTGGC TGCTGAAGCG CGGAGAGCTG 
TTCTTAGTGG AAGAAACCGG ACTTTTTCGA AAAATTGCCA GCCGGCCAAC GTGCTACCTT 
TTCCTGTTCA ACGATGTCCT GGTTGTGACC AAGAAGAAGA GCGAGGAGAG CTACATGGTC 
CAGGACTACG CCCAGATGAA CCACATCCAG GTGGAGAAGA TAGAGCCGTC TGAGCTCCCT 
CTGCCCGGGG GCGGCAACCG TAGCTCCTCC GTGCCCCACC CCTTCCAGGT GACCCTGCTT 
CGCAACAGCG AGGGCCGCCA GGAGCAGCTC CTGCTCTCCT CGGACTCCGC GAGTGACCGG 
GCACGGTGGA TCGTGGCGCT CACACACAGT GAGAGACAGT GGCAGGGCCT CTCCAGCAAA 
GGAGACCTGC CCCAGGTGGA GATCACCAAG GCCTTCTTCG CGAAGCAAGC AGACGAGGTC 
ACACTGCAGC AGGCGGACGT GGTCCTGGTT CTGCAGCAGG AGGATGGGTG GCTCTATGGC 
GAGAGGCTCC GGGACGGAGA GACGGGATGG TTCCCCGAGG ACTTTGCCCG CTTCATCACC 
AGCCGTGTGG CCGTGGAGGG CAATGTCCGC AGGATGGAGC GTCTGCGGGT GGAGACGGAC 
GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024302223.1
CDS	81..1346
Translation	MFEILTSEFSYQHSLSILVEEFLQSKELRATVTQMEHHHLFSNILDVLGASQRFFEDLEQRHKAQVLVEDISDILEEHAEKHFHPYIAYCSNEVYQQRTLQKLISSNAAFREALREIERRPACGGLPMLSFLILPMQRVTRLPLLMDTLCLKTQGHSERYKAASRALKAISKLVRQCNEGAHRMERMEQMYTLHTQLDFSKVKSLPLISASRWLLKRGELFLVEETGLFRKIASRPTCYLFLFNDVLVVTKKKSEESYMVQDYAQMNHIQVEKIEPSELPLPGGGNRSSSVPHPFQVTLLRNSEGRQEQLLLSSDSASDRARWIVALTHSERQWQGLSSKGDLPQVEITKAFFAKQADEVTLQQADVVLVLQQEDGWLYGERLRDGETGWFPEDFARFITSRVAVEGNVRRMERLRVETDV

Target ORF information:

RefSeq Version	XM_024446455.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rho guanine nucleotide exchange factor 16 (ARHGEF16), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024446455.1

ORF Insert Sequence:

ATGTTCGAGA TCCTCACGTC GGAGTTCTCC TACCAGCACA GCCTGAGCAT CCTGGTGGAG 
GAGTTCCTGC AGTCCAAGGA GCTGCGGGCG ACCGTGACCC AGATGGAGCA CCACCACCTC 
TTCTCCAACA TCCTGGATGT CCTGGGTGCC AGTCAGAGGT TCTTCGAGGA CCTGGAGCAG 
CGGCACAAGG CCCAGGTGCT GGTCGAGGAC ATCAGTGACA TCCTGGAGGA GCACGCTGAG 
AAGCACTTCC ACCCCTACAT CGCCTACTGC TCCAACGAGG TCTACCAACA GCGCACGCTG 
CAGAAGCTGA TAAGCAGCAA CGCCGCCTTC CGAGAGGCCC TGAGAGAGAT TGAGAGGCGG 
CCGGCGTGCG GGGGCCTGCC CATGCTCTCC TTCCTGATCC TCCCCATGCA GCGGGTGACC 
CGGCTGCCCC TCCTGATGGA TACGCTCTGC CTCAAGACCC AGGGCCACTC CGAAAGGTAC 
AAGGCTGCCA GCCGTGCACT GAAGGCCATC AGCAAGCTGG TGAGGCAGTG CAACGAGGGG 
GCCCACAGGA TGGAGCGCAT GGAGCAGATG TACACGCTGC ACACACAGCT GGACTTCAGC 
AAGGTCAAGT CCCTCCCACT GATCTCTGCC TCCCGGTGGC TGCTGAAGCG CGGAGAGCTG 
TTCTTAGTGG AAGAAACCGG ACTTTTTCGA AAAATTGCCA GCCGGCCAAC GTGCTACCTT 
TTCCTGTTCA ACGATGTCCT GGTTGTGACC AAGAAGAAGA GCGAGGAGAG CTACATGGTC 
CAGGACTACG CCCAGATGAA CCACATCCAG GTGGAGAAGA TAGAGCCGTC TGAGCTCCCT 
CTGCCCGGGG GCGGCAACCG TAGCTCCTCC GTGCCCCACC CCTTCCAGGT GACCCTGCTT 
CGCAACAGCG AGGGCCGCCA GGAGCAGCTC CTGCTCTCCT CGGACTCCGC GAGTGACCGG 
GCACGGTGGA TCGTGGCGCT CACACACAGT GAGAGACAGT GGCAGGGCCT CTCCAGCAAA 
GGAGACCTGC CCCAGGTGGA GATCACCAAG GCCTTCTTCG CGAAGCAAGC AGACGAGGTC 
ACACTGCAGC AGGCGGACGT GGTCCTGGTT CTGCAGCAGG AGGATGGGTG GCTCTATGGC 
GAGAGGCTCC GGGACGGAGA GACGGGATGG TTCCCCGAGG ACTTTGCCCG CTTCATCACC 
AGCCGTGTGG CCGTGGAGGG CAATGTCCGC AGGATGGAGC GTCTGCGGGT GGAGACGGAC 
GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ARHGEF16 ( NM_014448.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_055263.2 Homo sapiens Rho guanine nucleotide exchange factor 16 (ARHGEF16), mRNA.

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CloneID	OHu87258
Clone ID Related Accession (Same CDS sequence)	NM_014448.4 , XM_017001050.1 , XM_017001051.1
Accession Version	NM_014448.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2130bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	rho guanine nucleotide exchange factor 16
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL512413.23. On Nov 23, 2018 this sequence version replaced NM_014448.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK095984.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000378378.9/ ENSP00000367629.4 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCCAGC GGCACTCAGA CAGCTCCTTG GAGGAGAAGC TCCTGGGACA CCGCTTCCAC 
TCGGAGCTCC GGCTCGATGC CGGGGGGAAC CCAGCCTCCG GGCTCCCAAT GGTCCGTGGC 
TCCCCGCGTG TTAGAGACGA TGCCGCCTTC CAGCCCCAGG TCCCGGCACC CCCACAGCCT 
CGGCCCCCGG GGCACGAGGA GCCATGGCCC ATCGTCCTGA GCACAGAGAG CCCGGCGGCC 
CTCAAGCTGG GCACCCAACA GCTGATCCCT AAGAGCCTGG CTGTGGCCAG CAAGGCAAAG 
ACCCCAGCCC GCCACCAGAG CTTCGGGGCG GCTGTACTTA GCAGGGAGGC CGCCCGGCGG 
GACCCTAAGC TCCTCCCAGC CCCCAGCTTC TCCCTGGATG ACATGGACGT GGACAAGGAC 
CCCGGGGGCA TGCTGAGGCG GAACCTGCGG AACCAATCCT ACCGGGCGGC CATGAAGGGC 
CTGGGGAAGC CAGGTGGCCA GGGAGATGCC ATCCAGCTAA GCCCTAAGCT CCAGGCTCTG 
GCTGAGGAAC CCAGCCAGCC TCATACTCGG AGCCCGGCCA AAAACAAGAA GACGCTGGGG 
AGGAAACGTG GGCACAAGGG TTCCTTCAAG GACGACCCCC AGCTCTACCA GGAGATCCAG 
GAGCGGGGCC TGAACACCAG CCAGGAGTCT GATGACGACA TCCTCGATGA GTCCTCCAGC 
CCCGAGGGAA CCCAGAAGGT GGACGCCACC ATTGTGGTCA AGAGCTACCG GCCCGCCCAG 
GTCACCTGGA GCCAGCTCCC AGAGGTGGTG GAATTGGGCA TCCTGGACCA GCTCTCCACT 
GAGGAGCGGA AAAGGCAGGA GGCCATGTTC GAGATCCTCA CGTCGGAGTT CTCCTACCAG 
CACAGCCTGA GCATCCTGGT GGAGGAGTTC CTGCAGTCCA AGGAGCTGCG GGCGACCGTG 
ACCCAGATGG AGCACCACCA CCTCTTCTCC AACATCCTGG ATGTCCTGGG TGCCAGTCAG 
AGGTTCTTCG AGGACCTGGA GCAGCGGCAC AAGGCCCAGG TGCTGGTCGA GGACATCAGT 
GACATCCTGG AGGAGCACGC TGAGAAGCAC TTCCACCCCT ACATCGCCTA CTGCTCCAAC 
GAGGTCTACC AACAGCGCAC GCTGCAGAAG CTGATAAGCA GCAACGCCGC CTTCCGAGAG 
GCCCTGAGAG AGATTGAGAG GCGGCCGGCG TGCGGGGGCC TGCCCATGCT CTCCTTCCTG 
ATCCTCCCCA TGCAGCGGGT GACCCGGCTG CCCCTCCTGA TGGATACGCT CTGCCTCAAG 
ACCCAGGGCC ACTCCGAAAG GTACAAGGCT GCCAGCCGTG CACTGAAGGC CATCAGCAAG 
CTGGTGAGGC AGTGCAACGA GGGGGCCCAC AGGATGGAGC GCATGGAGCA GATGTACACG 
CTGCACACAC AGCTGGACTT CAGCAAGGTC AAGTCCCTCC CACTGATCTC TGCCTCCCGG 
TGGCTGCTGA AGCGCGGAGA GCTGTTCTTA GTGGAAGAAA CCGGACTTTT TCGAAAAATT 
GCCAGCCGGC CAACGTGCTA CCTTTTCCTG TTCAACGATG TCCTGGTTGT GACCAAGAAG 
AAGAGCGAGG AGAGCTACAT GGTCCAGGAC TACGCCCAGA TGAACCACAT CCAGGTGGAG 
AAGATAGAGC CGTCTGAGCT CCCTCTGCCC GGGGGCGGCA ACCGTAGCTC CTCCGTGCCC 
CACCCCTTCC AGGTGACCCT GCTTCGCAAC AGCGAGGGCC GCCAGGAGCA GCTCCTGCTC 
TCCTCGGACT CCGCGAGTGA CCGGGCACGG TGGATCGTGG CGCTCACACA CAGTGAGAGA 
CAGTGGCAGG GCCTCTCCAG CAAAGGAGAC CTGCCCCAGG TGGAGATCAC CAAGGCCTTC 
TTCGCGAAGC AAGCAGACGA GGTCACACTG CAGCAGGCGG ACGTGGTCCT GGTTCTGCAG 
CAGGAGGATG GGTGGCTCTA TGGCGAGAGG CTCCGGGACG GAGAGACGGG ATGGTTCCCC 
GAGGACTTTG CCCGCTTCAT CACCAGCCGT GTGGCCGTGG AGGGCAATGT CCGCAGGATG 
GAGCGTCTGC GGGTGGAGAC GGACGTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055263.2
CDS	167..2296
Translation	MAQRHSDSSLEEKLLGHRFHSELRLDAGGNPASGLPMVRGSPRVRDDAAFQPQVPAPPQPRPPGHEEPWPIVLSTESPAALKLGTQQLIPKSLAVASKAKTPARHQSFGAAVLSREAARRDPKLLPAPSFSLDDMDVDKDPGGMLRRNLRNQSYRAAMKGLGKPGGQGDAIQLSPKLQALAEEPSQPHTRSPAKNKKTLGRKRGHKGSFKDDPQLYQEIQERGLNTSQESDDDILDESSSPEGTQKVDATIVVKSYRPAQVTWSQLPEVVELGILDQLSTEERKRQEAMFEILTSEFSYQHSLSILVEEFLQSKELRATVTQMEHHHLFSNILDVLGASQRFFEDLEQRHKAQVLVEDISDILEEHAEKHFHPYIAYCSNEVYQQRTLQKLISSNAAFREALREIERRPACGGLPMLSFLILPMQRVTRLPLLMDTLCLKTQGHSERYKAASRALKAISKLVRQCNEGAHRMERMEQMYTLHTQLDFSKVKSLPLISASRWLLKRGELFLVEETGLFRKIASRPTCYLFLFNDVLVVTKKKSEESYMVQDYAQMNHIQVEKIEPSELPLPGGGNRSSSVPHPFQVTLLRNSEGRQEQLLLSSDSASDRARWIVALTHSERQWQGLSSKGDLPQVEITKAFFAKQADEVTLQQADVVLVLQQEDGWLYGERLRDGETGWFPEDFARFITSRVAVEGNVRRMERLRVETDV

Target ORF information:

RefSeq Version	NM_014448.4
Organism	Homo sapiens(human)
Definition	Homo sapiens Rho guanine nucleotide exchange factor 16 (ARHGEF16), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014448.4

ORF Insert Sequence:

ATGGCCCAGC GGCACTCAGA CAGCTCCTTG GAGGAGAAGC TCCTGGGACA CCGCTTCCAC 
TCGGAGCTCC GGCTCGATGC CGGGGGGAAC CCAGCCTCCG GGCTCCCAAT GGTCCGTGGC 
TCCCCGCGTG TTAGAGACGA TGCCGCCTTC CAGCCCCAGG TCCCGGCACC CCCACAGCCT 
CGGCCCCCGG GGCACGAGGA GCCATGGCCC ATCGTCCTGA GCACAGAGAG CCCGGCGGCC 
CTCAAGCTGG GCACCCAACA GCTGATCCCT AAGAGCCTGG CTGTGGCCAG CAAGGCAAAG 
ACCCCAGCCC GCCACCAGAG CTTCGGGGCG GCTGTACTTA GCAGGGAGGC CGCCCGGCGG 
GACCCTAAGC TCCTCCCAGC CCCCAGCTTC TCCCTGGATG ACATGGACGT GGACAAGGAC 
CCCGGGGGCA TGCTGAGGCG GAACCTGCGG AACCAATCCT ACCGGGCGGC CATGAAGGGC 
CTGGGGAAGC CAGGTGGCCA GGGAGATGCC ATCCAGCTAA GCCCTAAGCT CCAGGCTCTG 
GCTGAGGAAC CCAGCCAGCC TCATACTCGG AGCCCGGCCA AAAACAAGAA GACGCTGGGG 
AGGAAACGTG GGCACAAGGG TTCCTTCAAG GACGACCCCC AGCTCTACCA GGAGATCCAG 
GAGCGGGGCC TGAACACCAG CCAGGAGTCT GATGACGACA TCCTCGATGA GTCCTCCAGC 
CCCGAGGGAA CCCAGAAGGT GGACGCCACC ATTGTGGTCA AGAGCTACCG GCCCGCCCAG 
GTCACCTGGA GCCAGCTCCC AGAGGTGGTG GAATTGGGCA TCCTGGACCA GCTCTCCACT 
GAGGAGCGGA AAAGGCAGGA GGCCATGTTC GAGATCCTCA CGTCGGAGTT CTCCTACCAG 
CACAGCCTGA GCATCCTGGT GGAGGAGTTC CTGCAGTCCA AGGAGCTGCG GGCGACCGTG 
ACCCAGATGG AGCACCACCA CCTCTTCTCC AACATCCTGG ATGTCCTGGG TGCCAGTCAG 
AGGTTCTTCG AGGACCTGGA GCAGCGGCAC AAGGCCCAGG TGCTGGTCGA GGACATCAGT 
GACATCCTGG AGGAGCACGC TGAGAAGCAC TTCCACCCCT ACATCGCCTA CTGCTCCAAC 
GAGGTCTACC AACAGCGCAC GCTGCAGAAG CTGATAAGCA GCAACGCCGC CTTCCGAGAG 
GCCCTGAGAG AGATTGAGAG GCGGCCGGCG TGCGGGGGCC TGCCCATGCT CTCCTTCCTG 
ATCCTCCCCA TGCAGCGGGT GACCCGGCTG CCCCTCCTGA TGGATACGCT CTGCCTCAAG 
ACCCAGGGCC ACTCCGAAAG GTACAAGGCT GCCAGCCGTG CACTGAAGGC CATCAGCAAG 
CTGGTGAGGC AGTGCAACGA GGGGGCCCAC AGGATGGAGC GCATGGAGCA GATGTACACG 
CTGCACACAC AGCTGGACTT CAGCAAGGTC AAGTCCCTCC CACTGATCTC TGCCTCCCGG 
TGGCTGCTGA AGCGCGGAGA GCTGTTCTTA GTGGAAGAAA CCGGACTTTT TCGAAAAATT 
GCCAGCCGGC CAACGTGCTA CCTTTTCCTG TTCAACGATG TCCTGGTTGT GACCAAGAAG 
AAGAGCGAGG AGAGCTACAT GGTCCAGGAC TACGCCCAGA TGAACCACAT CCAGGTGGAG 
AAGATAGAGC CGTCTGAGCT CCCTCTGCCC GGGGGCGGCA ACCGTAGCTC CTCCGTGCCC 
CACCCCTTCC AGGTGACCCT GCTTCGCAAC AGCGAGGGCC GCCAGGAGCA GCTCCTGCTC 
TCCTCGGACT CCGCGAGTGA CCGGGCACGG TGGATCGTGG CGCTCACACA CAGTGAGAGA 
CAGTGGCAGG GCCTCTCCAG CAAAGGAGAC CTGCCCCAGG TGGAGATCAC CAAGGCCTTC 
TTCGCGAAGC AAGCAGACGA GGTCACACTG CAGCAGGCGG ACGTGGTCCT GGTTCTGCAG 
CAGGAGGATG GGTGGCTCTA TGGCGAGAGG CTCCGGGACG GAGAGACGGG ATGGTTCCCC 
GAGGACTTTG CCCGCTTCAT CACCAGCCGT GTGGCCGTGG AGGGCAATGT CCGCAGGATG 
GAGCGTCTGC GGGTGGAGAC GGACGTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ARHGEF16 ( XM_017001049.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016856538.1 Homo sapiens Rho guanine nucleotide exchange factor 16 (ARHGEF16), transcript variant X1, mRNA.

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CloneID	OHu87257
Clone ID Related Accession (Same CDS sequence)	XM_017001049.1
Accession Version	XM_017001049.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2181bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	rho guanine nucleotide exchange factor 16 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCTTCA GGGCAATGAG GGCCGGGAGC AGGACCCCAC AGCCGCCCAG CATGGCCCAG 
CGGCACTCAG ACAGCTCCTT GGAGGAGAAG CTCCTGGGAC ACCGCTTCCA CTCGGAGCTC 
CGGCTCGATG CCGGGGGGAA CCCAGCCTCC GGGCTCCCAA TGGTCCGTGG CTCCCCGCGT 
GTTAGAGACG ATGCCGCCTT CCAGCCCCAG GTCCCGGCAC CCCCACAGCC TCGGCCCCCG 
GGGCACGAGG AGCCATGGCC CATCGTCCTG AGCACAGAGA GCCCGGCGGC CCTCAAGCTG 
GGCACCCAAC AGCTGATCCC TAAGAGCCTG GCTGTGGCCA GCAAGGCAAA GACCCCAGCC 
CGCCACCAGA GCTTCGGGGC GGCTGTACTT AGCAGGGAGG CCGCCCGGCG GGACCCTAAG 
CTCCTCCCAG CCCCCAGCTT CTCCCTGGAT GACATGGACG TGGACAAGGA CCCCGGGGGC 
ATGCTGAGGC GGAACCTGCG GAACCAATCC TACCGGGCGG CCATGAAGGG CCTGGGGAAG 
CCAGGTGGCC AGGGAGATGC CATCCAGCTA AGCCCTAAGC TCCAGGCTCT GGCTGAGGAA 
CCCAGCCAGC CTCATACTCG GAGCCCGGCC AAAAACAAGA AGACGCTGGG GAGGAAACGT 
GGGCACAAGG GTTCCTTCAA GGACGACCCC CAGCTCTACC AGGAGATCCA GGAGCGGGGC 
CTGAACACCA GCCAGGAGTC TGATGACGAC ATCCTCGATG AGTCCTCCAG CCCCGAGGGA 
ACCCAGAAGG TGGACGCCAC CATTGTGGTC AAGAGCTACC GGCCCGCCCA GGTCACCTGG 
AGCCAGCTCC CAGAGGTGGT GGAATTGGGC ATCCTGGACC AGCTCTCCAC TGAGGAGCGG 
AAAAGGCAGG AGGCCATGTT CGAGATCCTC ACGTCGGAGT TCTCCTACCA GCACAGCCTG 
AGCATCCTGG TGGAGGAGTT CCTGCAGTCC AAGGAGCTGC GGGCGACCGT GACCCAGATG 
GAGCACCACC ACCTCTTCTC CAACATCCTG GATGTCCTGG GTGCCAGTCA GAGGTTCTTC 
GAGGACCTGG AGCAGCGGCA CAAGGCCCAG GTGCTGGTCG AGGACATCAG TGACATCCTG 
GAGGAGCACG CTGAGAAGCA CTTCCACCCC TACATCGCCT ACTGCTCCAA CGAGGTCTAC 
CAACAGCGCA CGCTGCAGAA GCTGATAAGC AGCAACGCCG CCTTCCGAGA GGCCCTGAGA 
GAGATTGAGA GGCGGCCGGC GTGCGGGGGC CTGCCCATGC TCTCCTTCCT GATCCTCCCC 
ATGCAGCGGG TGACCCGGCT GCCCCTCCTG ATGGATACGC TCTGCCTCAA GACCCAGGGC 
CACTCCGAAA GGTACAAGGC TGCCAGCCGT GCACTGAAGG CCATCAGCAA GCTGGTGAGG 
CAGTGCAACG AGGGGGCCCA CAGGATGGAG CGCATGGAGC AGATGTACAC GCTGCACACA 
CAGCTGGACT TCAGCAAGGT CAAGTCCCTC CCACTGATCT CTGCCTCCCG GTGGCTGCTG 
AAGCGCGGAG AGCTGTTCTT AGTGGAAGAA ACCGGACTTT TTCGAAAAAT TGCCAGCCGG 
CCAACGTGCT ACCTTTTCCT GTTCAACGAT GTCCTGGTTG TGACCAAGAA GAAGAGCGAG 
GAGAGCTACA TGGTCCAGGA CTACGCCCAG ATGAACCACA TCCAGGTGGA GAAGATAGAG 
CCGTCTGAGC TCCCTCTGCC CGGGGGCGGC AACCGTAGCT CCTCCGTGCC CCACCCCTTC 
CAGGTGACCC TGCTTCGCAA CAGCGAGGGC CGCCAGGAGC AGCTCCTGCT CTCCTCGGAC 
TCCGCGAGTG ACCGGGCACG GTGGATCGTG GCGCTCACAC ACAGTGAGAG ACAGTGGCAG 
GGCCTCTCCA GCAAAGGAGA CCTGCCCCAG GTGGAGATCA CCAAGGCCTT CTTCGCGAAG 
CAAGCAGACG AGGTCACACT GCAGCAGGCG GACGTGGTCC TGGTTCTGCA GCAGGAGGAT 
GGGTGGCTCT ATGGCGAGAG GCTCCGGGAC GGAGAGACGG GATGGTTCCC CGAGGACTTT 
GCCCGCTTCA TCACCAGCCG TGTGGCCGTG GAGGGCAATG TCCGCAGGAT GGAGCGTCTG 
CGGGTGGAGA CGGACGTGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016856538.1
CDS	799..2979
Translation	MSFRAMRAGSRTPQPPSMAQRHSDSSLEEKLLGHRFHSELRLDAGGNPASGLPMVRGSPRVRDDAAFQPQVPAPPQPRPPGHEEPWPIVLSTESPAALKLGTQQLIPKSLAVASKAKTPARHQSFGAAVLSREAARRDPKLLPAPSFSLDDMDVDKDPGGMLRRNLRNQSYRAAMKGLGKPGGQGDAIQLSPKLQALAEEPSQPHTRSPAKNKKTLGRKRGHKGSFKDDPQLYQEIQERGLNTSQESDDDILDESSSPEGTQKVDATIVVKSYRPAQVTWSQLPEVVELGILDQLSTEERKRQEAMFEILTSEFSYQHSLSILVEEFLQSKELRATVTQMEHHHLFSNILDVLGASQRFFEDLEQRHKAQVLVEDISDILEEHAEKHFHPYIAYCSNEVYQQRTLQKLISSNAAFREALREIERRPACGGLPMLSFLILPMQRVTRLPLLMDTLCLKTQGHSERYKAASRALKAISKLVRQCNEGAHRMERMEQMYTLHTQLDFSKVKSLPLISASRWLLKRGELFLVEETGLFRKIASRPTCYLFLFNDVLVVTKKKSEESYMVQDYAQMNHIQVEKIEPSELPLPGGGNRSSSVPHPFQVTLLRNSEGRQEQLLLSSDSASDRARWIVALTHSERQWQGLSSKGDLPQVEITKAFFAKQADEVTLQQADVVLVLQQEDGWLYGERLRDGETGWFPEDFARFITSRVAVEGNVRRMERLRVETDV

Target ORF information:

RefSeq Version	XM_017001049.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rho guanine nucleotide exchange factor 16 (ARHGEF16), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017001049.1

ORF Insert Sequence:

ATGTCCTTCA GGGCAATGAG GGCCGGGAGC AGGACCCCAC AGCCGCCCAG CATGGCCCAG 
CGGCACTCAG ACAGCTCCTT GGAGGAGAAG CTCCTGGGAC ACCGCTTCCA CTCGGAGCTC 
CGGCTCGATG CCGGGGGGAA CCCAGCCTCC GGGCTCCCAA TGGTCCGTGG CTCCCCGCGT 
GTTAGAGACG ATGCCGCCTT CCAGCCCCAG GTCCCGGCAC CCCCACAGCC TCGGCCCCCG 
GGGCACGAGG AGCCATGGCC CATCGTCCTG AGCACAGAGA GCCCGGCGGC CCTCAAGCTG 
GGCACCCAAC AGCTGATCCC TAAGAGCCTG GCTGTGGCCA GCAAGGCAAA GACCCCAGCC 
CGCCACCAGA GCTTCGGGGC GGCTGTACTT AGCAGGGAGG CCGCCCGGCG GGACCCTAAG 
CTCCTCCCAG CCCCCAGCTT CTCCCTGGAT GACATGGACG TGGACAAGGA CCCCGGGGGC 
ATGCTGAGGC GGAACCTGCG GAACCAATCC TACCGGGCGG CCATGAAGGG CCTGGGGAAG 
CCAGGTGGCC AGGGAGATGC CATCCAGCTA AGCCCTAAGC TCCAGGCTCT GGCTGAGGAA 
CCCAGCCAGC CTCATACTCG GAGCCCGGCC AAAAACAAGA AGACGCTGGG GAGGAAACGT 
GGGCACAAGG GTTCCTTCAA GGACGACCCC CAGCTCTACC AGGAGATCCA GGAGCGGGGC 
CTGAACACCA GCCAGGAGTC TGATGACGAC ATCCTCGATG AGTCCTCCAG CCCCGAGGGA 
ACCCAGAAGG TGGACGCCAC CATTGTGGTC AAGAGCTACC GGCCCGCCCA GGTCACCTGG 
AGCCAGCTCC CAGAGGTGGT GGAATTGGGC ATCCTGGACC AGCTCTCCAC TGAGGAGCGG 
AAAAGGCAGG AGGCCATGTT CGAGATCCTC ACGTCGGAGT TCTCCTACCA GCACAGCCTG 
AGCATCCTGG TGGAGGAGTT CCTGCAGTCC AAGGAGCTGC GGGCGACCGT GACCCAGATG 
GAGCACCACC ACCTCTTCTC CAACATCCTG GATGTCCTGG GTGCCAGTCA GAGGTTCTTC 
GAGGACCTGG AGCAGCGGCA CAAGGCCCAG GTGCTGGTCG AGGACATCAG TGACATCCTG 
GAGGAGCACG CTGAGAAGCA CTTCCACCCC TACATCGCCT ACTGCTCCAA CGAGGTCTAC 
CAACAGCGCA CGCTGCAGAA GCTGATAAGC AGCAACGCCG CCTTCCGAGA GGCCCTGAGA 
GAGATTGAGA GGCGGCCGGC GTGCGGGGGC CTGCCCATGC TCTCCTTCCT GATCCTCCCC 
ATGCAGCGGG TGACCCGGCT GCCCCTCCTG ATGGATACGC TCTGCCTCAA GACCCAGGGC 
CACTCCGAAA GGTACAAGGC TGCCAGCCGT GCACTGAAGG CCATCAGCAA GCTGGTGAGG 
CAGTGCAACG AGGGGGCCCA CAGGATGGAG CGCATGGAGC AGATGTACAC GCTGCACACA 
CAGCTGGACT TCAGCAAGGT CAAGTCCCTC CCACTGATCT CTGCCTCCCG GTGGCTGCTG 
AAGCGCGGAG AGCTGTTCTT AGTGGAAGAA ACCGGACTTT TTCGAAAAAT TGCCAGCCGG 
CCAACGTGCT ACCTTTTCCT GTTCAACGAT GTCCTGGTTG TGACCAAGAA GAAGAGCGAG 
GAGAGCTACA TGGTCCAGGA CTACGCCCAG ATGAACCACA TCCAGGTGGA GAAGATAGAG 
CCGTCTGAGC TCCCTCTGCC CGGGGGCGGC AACCGTAGCT CCTCCGTGCC CCACCCCTTC 
CAGGTGACCC TGCTTCGCAA CAGCGAGGGC CGCCAGGAGC AGCTCCTGCT CTCCTCGGAC 
TCCGCGAGTG ACCGGGCACG GTGGATCGTG GCGCTCACAC ACAGTGAGAG ACAGTGGCAG 
GGCCTCTCCA GCAAAGGAGA CCTGCCCCAG GTGGAGATCA CCAAGGCCTT CTTCGCGAAG 
CAAGCAGACG AGGTCACACT GCAGCAGGCG GACGTGGTCC TGGTTCTGCA GCAGGAGGAT 
GGGTGGCTCT ATGGCGAGAG GCTCCGGGAC GGAGAGACGG GATGGTTCCC CGAGGACTTT 
GCCCGCTTCA TCACCAGCCG TGTGGCCGTG GAGGGCAATG TCCGCAGGAT GGAGCGTCTG 
CGGGTGGAGA CGGACGTGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ARHGEF16 ( XM_017001050.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016856539.1 Homo sapiens Rho guanine nucleotide exchange factor 16 (ARHGEF16), transcript variant X2, mRNA.

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CloneID	OHu87258
Clone ID Related Accession (Same CDS sequence)	NM_014448.4 , XM_017001050.1 , XM_017001051.1
Accession Version	XM_017001050.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2130bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	rho guanine nucleotide exchange factor 16 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCCAGC GGCACTCAGA CAGCTCCTTG GAGGAGAAGC TCCTGGGACA CCGCTTCCAC 
TCGGAGCTCC GGCTCGATGC CGGGGGGAAC CCAGCCTCCG GGCTCCCAAT GGTCCGTGGC 
TCCCCGCGTG TTAGAGACGA TGCCGCCTTC CAGCCCCAGG TCCCGGCACC CCCACAGCCT 
CGGCCCCCGG GGCACGAGGA GCCATGGCCC ATCGTCCTGA GCACAGAGAG CCCGGCGGCC 
CTCAAGCTGG GCACCCAACA GCTGATCCCT AAGAGCCTGG CTGTGGCCAG CAAGGCAAAG 
ACCCCAGCCC GCCACCAGAG CTTCGGGGCG GCTGTACTTA GCAGGGAGGC CGCCCGGCGG 
GACCCTAAGC TCCTCCCAGC CCCCAGCTTC TCCCTGGATG ACATGGACGT GGACAAGGAC 
CCCGGGGGCA TGCTGAGGCG GAACCTGCGG AACCAATCCT ACCGGGCGGC CATGAAGGGC 
CTGGGGAAGC CAGGTGGCCA GGGAGATGCC ATCCAGCTAA GCCCTAAGCT CCAGGCTCTG 
GCTGAGGAAC CCAGCCAGCC TCATACTCGG AGCCCGGCCA AAAACAAGAA GACGCTGGGG 
AGGAAACGTG GGCACAAGGG TTCCTTCAAG GACGACCCCC AGCTCTACCA GGAGATCCAG 
GAGCGGGGCC TGAACACCAG CCAGGAGTCT GATGACGACA TCCTCGATGA GTCCTCCAGC 
CCCGAGGGAA CCCAGAAGGT GGACGCCACC ATTGTGGTCA AGAGCTACCG GCCCGCCCAG 
GTCACCTGGA GCCAGCTCCC AGAGGTGGTG GAATTGGGCA TCCTGGACCA GCTCTCCACT 
GAGGAGCGGA AAAGGCAGGA GGCCATGTTC GAGATCCTCA CGTCGGAGTT CTCCTACCAG 
CACAGCCTGA GCATCCTGGT GGAGGAGTTC CTGCAGTCCA AGGAGCTGCG GGCGACCGTG 
ACCCAGATGG AGCACCACCA CCTCTTCTCC AACATCCTGG ATGTCCTGGG TGCCAGTCAG 
AGGTTCTTCG AGGACCTGGA GCAGCGGCAC AAGGCCCAGG TGCTGGTCGA GGACATCAGT 
GACATCCTGG AGGAGCACGC TGAGAAGCAC TTCCACCCCT ACATCGCCTA CTGCTCCAAC 
GAGGTCTACC AACAGCGCAC GCTGCAGAAG CTGATAAGCA GCAACGCCGC CTTCCGAGAG 
GCCCTGAGAG AGATTGAGAG GCGGCCGGCG TGCGGGGGCC TGCCCATGCT CTCCTTCCTG 
ATCCTCCCCA TGCAGCGGGT GACCCGGCTG CCCCTCCTGA TGGATACGCT CTGCCTCAAG 
ACCCAGGGCC ACTCCGAAAG GTACAAGGCT GCCAGCCGTG CACTGAAGGC CATCAGCAAG 
CTGGTGAGGC AGTGCAACGA GGGGGCCCAC AGGATGGAGC GCATGGAGCA GATGTACACG 
CTGCACACAC AGCTGGACTT CAGCAAGGTC AAGTCCCTCC CACTGATCTC TGCCTCCCGG 
TGGCTGCTGA AGCGCGGAGA GCTGTTCTTA GTGGAAGAAA CCGGACTTTT TCGAAAAATT 
GCCAGCCGGC CAACGTGCTA CCTTTTCCTG TTCAACGATG TCCTGGTTGT GACCAAGAAG 
AAGAGCGAGG AGAGCTACAT GGTCCAGGAC TACGCCCAGA TGAACCACAT CCAGGTGGAG 
AAGATAGAGC CGTCTGAGCT CCCTCTGCCC GGGGGCGGCA ACCGTAGCTC CTCCGTGCCC 
CACCCCTTCC AGGTGACCCT GCTTCGCAAC AGCGAGGGCC GCCAGGAGCA GCTCCTGCTC 
TCCTCGGACT CCGCGAGTGA CCGGGCACGG TGGATCGTGG CGCTCACACA CAGTGAGAGA 
CAGTGGCAGG GCCTCTCCAG CAAAGGAGAC CTGCCCCAGG TGGAGATCAC CAAGGCCTTC 
TTCGCGAAGC AAGCAGACGA GGTCACACTG CAGCAGGCGG ACGTGGTCCT GGTTCTGCAG 
CAGGAGGATG GGTGGCTCTA TGGCGAGAGG CTCCGGGACG GAGAGACGGG ATGGTTCCCC 
GAGGACTTTG CCCGCTTCAT CACCAGCCGT GTGGCCGTGG AGGGCAATGT CCGCAGGATG 
GAGCGTCTGC GGGTGGAGAC GGACGTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016856539.1
CDS	55..2184
Translation	MAQRHSDSSLEEKLLGHRFHSELRLDAGGNPASGLPMVRGSPRVRDDAAFQPQVPAPPQPRPPGHEEPWPIVLSTESPAALKLGTQQLIPKSLAVASKAKTPARHQSFGAAVLSREAARRDPKLLPAPSFSLDDMDVDKDPGGMLRRNLRNQSYRAAMKGLGKPGGQGDAIQLSPKLQALAEEPSQPHTRSPAKNKKTLGRKRGHKGSFKDDPQLYQEIQERGLNTSQESDDDILDESSSPEGTQKVDATIVVKSYRPAQVTWSQLPEVVELGILDQLSTEERKRQEAMFEILTSEFSYQHSLSILVEEFLQSKELRATVTQMEHHHLFSNILDVLGASQRFFEDLEQRHKAQVLVEDISDILEEHAEKHFHPYIAYCSNEVYQQRTLQKLISSNAAFREALREIERRPACGGLPMLSFLILPMQRVTRLPLLMDTLCLKTQGHSERYKAASRALKAISKLVRQCNEGAHRMERMEQMYTLHTQLDFSKVKSLPLISASRWLLKRGELFLVEETGLFRKIASRPTCYLFLFNDVLVVTKKKSEESYMVQDYAQMNHIQVEKIEPSELPLPGGGNRSSSVPHPFQVTLLRNSEGRQEQLLLSSDSASDRARWIVALTHSERQWQGLSSKGDLPQVEITKAFFAKQADEVTLQQADVVLVLQQEDGWLYGERLRDGETGWFPEDFARFITSRVAVEGNVRRMERLRVETDV

Target ORF information:

RefSeq Version	XM_017001050.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rho guanine nucleotide exchange factor 16 (ARHGEF16), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017001050.1

ORF Insert Sequence:

ATGGCCCAGC GGCACTCAGA CAGCTCCTTG GAGGAGAAGC TCCTGGGACA CCGCTTCCAC 
TCGGAGCTCC GGCTCGATGC CGGGGGGAAC CCAGCCTCCG GGCTCCCAAT GGTCCGTGGC 
TCCCCGCGTG TTAGAGACGA TGCCGCCTTC CAGCCCCAGG TCCCGGCACC CCCACAGCCT 
CGGCCCCCGG GGCACGAGGA GCCATGGCCC ATCGTCCTGA GCACAGAGAG CCCGGCGGCC 
CTCAAGCTGG GCACCCAACA GCTGATCCCT AAGAGCCTGG CTGTGGCCAG CAAGGCAAAG 
ACCCCAGCCC GCCACCAGAG CTTCGGGGCG GCTGTACTTA GCAGGGAGGC CGCCCGGCGG 
GACCCTAAGC TCCTCCCAGC CCCCAGCTTC TCCCTGGATG ACATGGACGT GGACAAGGAC 
CCCGGGGGCA TGCTGAGGCG GAACCTGCGG AACCAATCCT ACCGGGCGGC CATGAAGGGC 
CTGGGGAAGC CAGGTGGCCA GGGAGATGCC ATCCAGCTAA GCCCTAAGCT CCAGGCTCTG 
GCTGAGGAAC CCAGCCAGCC TCATACTCGG AGCCCGGCCA AAAACAAGAA GACGCTGGGG 
AGGAAACGTG GGCACAAGGG TTCCTTCAAG GACGACCCCC AGCTCTACCA GGAGATCCAG 
GAGCGGGGCC TGAACACCAG CCAGGAGTCT GATGACGACA TCCTCGATGA GTCCTCCAGC 
CCCGAGGGAA CCCAGAAGGT GGACGCCACC ATTGTGGTCA AGAGCTACCG GCCCGCCCAG 
GTCACCTGGA GCCAGCTCCC AGAGGTGGTG GAATTGGGCA TCCTGGACCA GCTCTCCACT 
GAGGAGCGGA AAAGGCAGGA GGCCATGTTC GAGATCCTCA CGTCGGAGTT CTCCTACCAG 
CACAGCCTGA GCATCCTGGT GGAGGAGTTC CTGCAGTCCA AGGAGCTGCG GGCGACCGTG 
ACCCAGATGG AGCACCACCA CCTCTTCTCC AACATCCTGG ATGTCCTGGG TGCCAGTCAG 
AGGTTCTTCG AGGACCTGGA GCAGCGGCAC AAGGCCCAGG TGCTGGTCGA GGACATCAGT 
GACATCCTGG AGGAGCACGC TGAGAAGCAC TTCCACCCCT ACATCGCCTA CTGCTCCAAC 
GAGGTCTACC AACAGCGCAC GCTGCAGAAG CTGATAAGCA GCAACGCCGC CTTCCGAGAG 
GCCCTGAGAG AGATTGAGAG GCGGCCGGCG TGCGGGGGCC TGCCCATGCT CTCCTTCCTG 
ATCCTCCCCA TGCAGCGGGT GACCCGGCTG CCCCTCCTGA TGGATACGCT CTGCCTCAAG 
ACCCAGGGCC ACTCCGAAAG GTACAAGGCT GCCAGCCGTG CACTGAAGGC CATCAGCAAG 
CTGGTGAGGC AGTGCAACGA GGGGGCCCAC AGGATGGAGC GCATGGAGCA GATGTACACG 
CTGCACACAC AGCTGGACTT CAGCAAGGTC AAGTCCCTCC CACTGATCTC TGCCTCCCGG 
TGGCTGCTGA AGCGCGGAGA GCTGTTCTTA GTGGAAGAAA CCGGACTTTT TCGAAAAATT 
GCCAGCCGGC CAACGTGCTA CCTTTTCCTG TTCAACGATG TCCTGGTTGT GACCAAGAAG 
AAGAGCGAGG AGAGCTACAT GGTCCAGGAC TACGCCCAGA TGAACCACAT CCAGGTGGAG 
AAGATAGAGC CGTCTGAGCT CCCTCTGCCC GGGGGCGGCA ACCGTAGCTC CTCCGTGCCC 
CACCCCTTCC AGGTGACCCT GCTTCGCAAC AGCGAGGGCC GCCAGGAGCA GCTCCTGCTC 
TCCTCGGACT CCGCGAGTGA CCGGGCACGG TGGATCGTGG CGCTCACACA CAGTGAGAGA 
CAGTGGCAGG GCCTCTCCAG CAAAGGAGAC CTGCCCCAGG TGGAGATCAC CAAGGCCTTC 
TTCGCGAAGC AAGCAGACGA GGTCACACTG CAGCAGGCGG ACGTGGTCCT GGTTCTGCAG 
CAGGAGGATG GGTGGCTCTA TGGCGAGAGG CTCCGGGACG GAGAGACGGG ATGGTTCCCC 
GAGGACTTTG CCCGCTTCAT CACCAGCCGT GTGGCCGTGG AGGGCAATGT CCGCAGGATG 
GAGCGTCTGC GGGTGGAGAC GGACGTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ARHGEF16 ( XM_017001051.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016856540.1 Homo sapiens Rho guanine nucleotide exchange factor 16 (ARHGEF16), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu87258
Clone ID Related Accession (Same CDS sequence)	NM_014448.4 , XM_017001050.1 , XM_017001051.1
Accession Version	XM_017001051.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2130bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	rho guanine nucleotide exchange factor 16 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCCAGC GGCACTCAGA CAGCTCCTTG GAGGAGAAGC TCCTGGGACA CCGCTTCCAC 
TCGGAGCTCC GGCTCGATGC CGGGGGGAAC CCAGCCTCCG GGCTCCCAAT GGTCCGTGGC 
TCCCCGCGTG TTAGAGACGA TGCCGCCTTC CAGCCCCAGG TCCCGGCACC CCCACAGCCT 
CGGCCCCCGG GGCACGAGGA GCCATGGCCC ATCGTCCTGA GCACAGAGAG CCCGGCGGCC 
CTCAAGCTGG GCACCCAACA GCTGATCCCT AAGAGCCTGG CTGTGGCCAG CAAGGCAAAG 
ACCCCAGCCC GCCACCAGAG CTTCGGGGCG GCTGTACTTA GCAGGGAGGC CGCCCGGCGG 
GACCCTAAGC TCCTCCCAGC CCCCAGCTTC TCCCTGGATG ACATGGACGT GGACAAGGAC 
CCCGGGGGCA TGCTGAGGCG GAACCTGCGG AACCAATCCT ACCGGGCGGC CATGAAGGGC 
CTGGGGAAGC CAGGTGGCCA GGGAGATGCC ATCCAGCTAA GCCCTAAGCT CCAGGCTCTG 
GCTGAGGAAC CCAGCCAGCC TCATACTCGG AGCCCGGCCA AAAACAAGAA GACGCTGGGG 
AGGAAACGTG GGCACAAGGG TTCCTTCAAG GACGACCCCC AGCTCTACCA GGAGATCCAG 
GAGCGGGGCC TGAACACCAG CCAGGAGTCT GATGACGACA TCCTCGATGA GTCCTCCAGC 
CCCGAGGGAA CCCAGAAGGT GGACGCCACC ATTGTGGTCA AGAGCTACCG GCCCGCCCAG 
GTCACCTGGA GCCAGCTCCC AGAGGTGGTG GAATTGGGCA TCCTGGACCA GCTCTCCACT 
GAGGAGCGGA AAAGGCAGGA GGCCATGTTC GAGATCCTCA CGTCGGAGTT CTCCTACCAG 
CACAGCCTGA GCATCCTGGT GGAGGAGTTC CTGCAGTCCA AGGAGCTGCG GGCGACCGTG 
ACCCAGATGG AGCACCACCA CCTCTTCTCC AACATCCTGG ATGTCCTGGG TGCCAGTCAG 
AGGTTCTTCG AGGACCTGGA GCAGCGGCAC AAGGCCCAGG TGCTGGTCGA GGACATCAGT 
GACATCCTGG AGGAGCACGC TGAGAAGCAC TTCCACCCCT ACATCGCCTA CTGCTCCAAC 
GAGGTCTACC AACAGCGCAC GCTGCAGAAG CTGATAAGCA GCAACGCCGC CTTCCGAGAG 
GCCCTGAGAG AGATTGAGAG GCGGCCGGCG TGCGGGGGCC TGCCCATGCT CTCCTTCCTG 
ATCCTCCCCA TGCAGCGGGT GACCCGGCTG CCCCTCCTGA TGGATACGCT CTGCCTCAAG 
ACCCAGGGCC ACTCCGAAAG GTACAAGGCT GCCAGCCGTG CACTGAAGGC CATCAGCAAG 
CTGGTGAGGC AGTGCAACGA GGGGGCCCAC AGGATGGAGC GCATGGAGCA GATGTACACG 
CTGCACACAC AGCTGGACTT CAGCAAGGTC AAGTCCCTCC CACTGATCTC TGCCTCCCGG 
TGGCTGCTGA AGCGCGGAGA GCTGTTCTTA GTGGAAGAAA CCGGACTTTT TCGAAAAATT 
GCCAGCCGGC CAACGTGCTA CCTTTTCCTG TTCAACGATG TCCTGGTTGT GACCAAGAAG 
AAGAGCGAGG AGAGCTACAT GGTCCAGGAC TACGCCCAGA TGAACCACAT CCAGGTGGAG 
AAGATAGAGC CGTCTGAGCT CCCTCTGCCC GGGGGCGGCA ACCGTAGCTC CTCCGTGCCC 
CACCCCTTCC AGGTGACCCT GCTTCGCAAC AGCGAGGGCC GCCAGGAGCA GCTCCTGCTC 
TCCTCGGACT CCGCGAGTGA CCGGGCACGG TGGATCGTGG CGCTCACACA CAGTGAGAGA 
CAGTGGCAGG GCCTCTCCAG CAAAGGAGAC CTGCCCCAGG TGGAGATCAC CAAGGCCTTC 
TTCGCGAAGC AAGCAGACGA GGTCACACTG CAGCAGGCGG ACGTGGTCCT GGTTCTGCAG 
CAGGAGGATG GGTGGCTCTA TGGCGAGAGG CTCCGGGACG GAGAGACGGG ATGGTTCCCC 
GAGGACTTTG CCCGCTTCAT CACCAGCCGT GTGGCCGTGG AGGGCAATGT CCGCAGGATG 
GAGCGTCTGC GGGTGGAGAC GGACGTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016856540.1
CDS	260..2389
Translation	MAQRHSDSSLEEKLLGHRFHSELRLDAGGNPASGLPMVRGSPRVRDDAAFQPQVPAPPQPRPPGHEEPWPIVLSTESPAALKLGTQQLIPKSLAVASKAKTPARHQSFGAAVLSREAARRDPKLLPAPSFSLDDMDVDKDPGGMLRRNLRNQSYRAAMKGLGKPGGQGDAIQLSPKLQALAEEPSQPHTRSPAKNKKTLGRKRGHKGSFKDDPQLYQEIQERGLNTSQESDDDILDESSSPEGTQKVDATIVVKSYRPAQVTWSQLPEVVELGILDQLSTEERKRQEAMFEILTSEFSYQHSLSILVEEFLQSKELRATVTQMEHHHLFSNILDVLGASQRFFEDLEQRHKAQVLVEDISDILEEHAEKHFHPYIAYCSNEVYQQRTLQKLISSNAAFREALREIERRPACGGLPMLSFLILPMQRVTRLPLLMDTLCLKTQGHSERYKAASRALKAISKLVRQCNEGAHRMERMEQMYTLHTQLDFSKVKSLPLISASRWLLKRGELFLVEETGLFRKIASRPTCYLFLFNDVLVVTKKKSEESYMVQDYAQMNHIQVEKIEPSELPLPGGGNRSSSVPHPFQVTLLRNSEGRQEQLLLSSDSASDRARWIVALTHSERQWQGLSSKGDLPQVEITKAFFAKQADEVTLQQADVVLVLQQEDGWLYGERLRDGETGWFPEDFARFITSRVAVEGNVRRMERLRVETDV

Target ORF information:

RefSeq Version	XM_017001051.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rho guanine nucleotide exchange factor 16 (ARHGEF16), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017001051.1

ORF Insert Sequence:

ATGGCCCAGC GGCACTCAGA CAGCTCCTTG GAGGAGAAGC TCCTGGGACA CCGCTTCCAC 
TCGGAGCTCC GGCTCGATGC CGGGGGGAAC CCAGCCTCCG GGCTCCCAAT GGTCCGTGGC 
TCCCCGCGTG TTAGAGACGA TGCCGCCTTC CAGCCCCAGG TCCCGGCACC CCCACAGCCT 
CGGCCCCCGG GGCACGAGGA GCCATGGCCC ATCGTCCTGA GCACAGAGAG CCCGGCGGCC 
CTCAAGCTGG GCACCCAACA GCTGATCCCT AAGAGCCTGG CTGTGGCCAG CAAGGCAAAG 
ACCCCAGCCC GCCACCAGAG CTTCGGGGCG GCTGTACTTA GCAGGGAGGC CGCCCGGCGG 
GACCCTAAGC TCCTCCCAGC CCCCAGCTTC TCCCTGGATG ACATGGACGT GGACAAGGAC 
CCCGGGGGCA TGCTGAGGCG GAACCTGCGG AACCAATCCT ACCGGGCGGC CATGAAGGGC 
CTGGGGAAGC CAGGTGGCCA GGGAGATGCC ATCCAGCTAA GCCCTAAGCT CCAGGCTCTG 
GCTGAGGAAC CCAGCCAGCC TCATACTCGG AGCCCGGCCA AAAACAAGAA GACGCTGGGG 
AGGAAACGTG GGCACAAGGG TTCCTTCAAG GACGACCCCC AGCTCTACCA GGAGATCCAG 
GAGCGGGGCC TGAACACCAG CCAGGAGTCT GATGACGACA TCCTCGATGA GTCCTCCAGC 
CCCGAGGGAA CCCAGAAGGT GGACGCCACC ATTGTGGTCA AGAGCTACCG GCCCGCCCAG 
GTCACCTGGA GCCAGCTCCC AGAGGTGGTG GAATTGGGCA TCCTGGACCA GCTCTCCACT 
GAGGAGCGGA AAAGGCAGGA GGCCATGTTC GAGATCCTCA CGTCGGAGTT CTCCTACCAG 
CACAGCCTGA GCATCCTGGT GGAGGAGTTC CTGCAGTCCA AGGAGCTGCG GGCGACCGTG 
ACCCAGATGG AGCACCACCA CCTCTTCTCC AACATCCTGG ATGTCCTGGG TGCCAGTCAG 
AGGTTCTTCG AGGACCTGGA GCAGCGGCAC AAGGCCCAGG TGCTGGTCGA GGACATCAGT 
GACATCCTGG AGGAGCACGC TGAGAAGCAC TTCCACCCCT ACATCGCCTA CTGCTCCAAC 
GAGGTCTACC AACAGCGCAC GCTGCAGAAG CTGATAAGCA GCAACGCCGC CTTCCGAGAG 
GCCCTGAGAG AGATTGAGAG GCGGCCGGCG TGCGGGGGCC TGCCCATGCT CTCCTTCCTG 
ATCCTCCCCA TGCAGCGGGT GACCCGGCTG CCCCTCCTGA TGGATACGCT CTGCCTCAAG 
ACCCAGGGCC ACTCCGAAAG GTACAAGGCT GCCAGCCGTG CACTGAAGGC CATCAGCAAG 
CTGGTGAGGC AGTGCAACGA GGGGGCCCAC AGGATGGAGC GCATGGAGCA GATGTACACG 
CTGCACACAC AGCTGGACTT CAGCAAGGTC AAGTCCCTCC CACTGATCTC TGCCTCCCGG 
TGGCTGCTGA AGCGCGGAGA GCTGTTCTTA GTGGAAGAAA CCGGACTTTT TCGAAAAATT 
GCCAGCCGGC CAACGTGCTA CCTTTTCCTG TTCAACGATG TCCTGGTTGT GACCAAGAAG 
AAGAGCGAGG AGAGCTACAT GGTCCAGGAC TACGCCCAGA TGAACCACAT CCAGGTGGAG 
AAGATAGAGC CGTCTGAGCT CCCTCTGCCC GGGGGCGGCA ACCGTAGCTC CTCCGTGCCC 
CACCCCTTCC AGGTGACCCT GCTTCGCAAC AGCGAGGGCC GCCAGGAGCA GCTCCTGCTC 
TCCTCGGACT CCGCGAGTGA CCGGGCACGG TGGATCGTGG CGCTCACACA CAGTGAGAGA 
CAGTGGCAGG GCCTCTCCAG CAAAGGAGAC CTGCCCCAGG TGGAGATCAC CAAGGCCTTC 
TTCGCGAAGC AAGCAGACGA GGTCACACTG CAGCAGGCGG ACGTGGTCCT GGTTCTGCAG 
CAGGAGGATG GGTGGCTCTA TGGCGAGAGG CTCCGGGACG GAGAGACGGG ATGGTTCCCC 
GAGGACTTTG CCCGCTTCAT CACCAGCCGT GTGGCCGTGG AGGGCAATGT CCGCAGGATG 
GAGCGTCTGC GGGTGGAGAC GGACGTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
Science signaling7(354)rs7(2014 Dec)
Guo Z,Neilson LJ,Zhong H,Murray PS,Zanivan S,Zaidel-Bar R

The HPV16 E6 binding protein Tip-1 interacts with ARHGEF16, which activates Cdc42.
British journal of cancer104(2)324-31(2011 Jan)
Oliver AW,He X,Borthwick K,Donne AJ,Hampson L,Hampson IN

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ARHGEF16 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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