ELP4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ELP4
Entrez Gene ID	26610
Full Name	elongator acetyltransferase complex subunit 4
Synonyms	AN,AN2,C11orf19,PAX6NEB,PAXNEB,dJ68P15A.1,hELP4
General protein information	Preferred Names elongator acetyltransferase complex subunit 4 Names elongator complex protein 4 PAX6 neighbor gene protein elongation protein 4 homolog
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11p13
Summary	This gene encodes a component of the six subunit elongator complex, a histone acetyltransferase complex that associates directly with RNA polymerase II during transcriptional elongation. The human gene can partially complement sensitivity phenotypes of yeast ELP4 deletion mutants. This gene has also been associated with Rolandic epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013].
Disorder MIM:	606985
Disorder Html:	?Aniridia 2, 617141 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_019040.5	NP_061913.3	elongator complex protein 4 isoform 1
NM_001288725.2	NP_001275654.1	elongator complex protein 4 isoform 2
NM_001288725.1	NP_001275654.1	elongator complex protein 4 isoform 2
NM_019040.4	NP_061913.3	elongator complex protein 4 isoform 1
NM_001288726.1	NP_001275655.1	elongator complex protein 4 isoform 3
NM_001288726.2	NP_001275655.1	elongator complex protein 4 isoform 3

Pathways from BioSystems

Homologies

Drosophila melanogaster (fruit fly)	CG6907	NP_608932.1
Oryza sativa (rice)	Os06g0639600	NP_001058161.1
Canis lupus familiaris (dog)	ELP4	XP_540560.2
Rattus norvegicus (Norway rat)	RGD1566052	NP_001108519.1
Rattus norvegicus (Norway rat)	LOC365839	XP_003749373.1
Gallus gallus (chicken)	ELP4	XP_426160.4
Homo sapiens (human)	ELP4	NP_061913.3
	ELP4	XP_001085806.1
Bos taurus (cattle)	ELP4	NP_001033773.1
Danio rerio (zebrafish)	elp4	NP_001017638.1
Caenorhabditis elegans (roundworm)	elpc-4	NP_501343.1
Xenopus tropicalis (tropical clawed frog)	elp4	XP_002938755.1
Pan troglodytes (chimpanzee)	ELP4	XP_508351.2
Mus musculus (house mouse)	Elp4	NP_076365.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010407	XP_311542.4
Arabidopsis thaliana (thale cress)	ELO1	NP_566388.2

Gene Ontology
Bibliography

Related articles in PubMed

Microdeletions of ELP4 Are Associated with Language Impairment, Autism Spectrum Disorder, and Mental Retardation.
Addis L, Ahn JW, Dobson R, Dixit A, Ogilvie CM, Pinto D, Vaags AK, Coon H, Chaste P, Wilson S, Parr JR, Andrieux J, Lenne B, Tumer Z, Leuzzi V, Aubell K, Koillinen H, Curran S, Marshall CR, Scherer SW, Strug LJ, Collier DA, Pal DK
Human mutation36(9)842-50(2015 Sep)

Association of brain-derived neurotrophic factor (BDNF) and elongator protein complex 4 (ELP4) polymorphisms with benign epilepsy with centrotemporal spikes in a Greek population.
Gkampeta A, Fidani L, Clarim?n J, Kalinderi K, Katopodi T, Zafeiriou D, Pavlou E
Epilepsy research108(10)1734-9(2014 Dec)

Genome-wide association and admixture analysis of glaucoma in the Women's Health Initiative.
Hoffmann TJ, Tang H, Thornton TA, Caan B, Haan M, Millen AE, Thomas F, Risch N
Human molecular genetics23(24)6634-43(2014 Dec)

Analysis of ELP4, SRPX2, and interacting genes in typical and atypical rolandic epilepsy.
Reinthaler EM, Lal D, Jurkowski W, Feucht M, Steinb?ck H, Gruber-Sedlmayr U, Ronen GM, Geldner J, Haberlandt E, Neophytou B, Hahn A, Altm?ller J, Thiele H, Toliat MR, , Lerche H, N?rnberg P, Sander T, Neubauer BA, Zimprich F
Epilepsia55(8)e89-93(2014 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Our results suggest that ELP4 deletions are highly likely to be pathogenic, predisposing to a range of neurodevelopmental phenotypes from ASD to language impairment and epilepsy.
Title: Microdeletions of ELP4 Are Associated with Language Impairment, Autism Spectrum Disorder, and Mental Retardation.

Results show no difference in BDNF and ELP4 genotype frequencies between benign epilepsy with centrotemporal spikes patients and controls; haplotype analysis also revealed no statistical difference
Title: Association of brain-derived neurotrophic factor (BDNF) and elongator protein complex 4 (ELP4) polymorphisms with benign epilepsy with centrotemporal spikes in a Greek population.

No association of SNPs in the ELP4 gene was detected in rolandic epilepsy patients.
Title: Analysis of ELP4, SRPX2, and interacting genes in typical and atypical rolandic epilepsy.

Data suggest that a non-coding mutation in ELP4 impairs brain-specific Elongator-mediated interaction of genes implicated in brain development, resulting in susceptibility to seizures and neurodevelopmental disorders.
Title: Centrotemporal sharp wave EEG trait in rolandic epilepsy maps to Elongator Protein Complex 4 (ELP4).

The following ELP4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ELP4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu16071	NM_001288726.2 Latest version!	Homo sapiens elongator acetyltransferase complex subunit 4 (ELP4), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu16081	NM_001288725.2 Latest version!	Homo sapiens elongator acetyltransferase complex subunit 4 (ELP4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu21125	NM_019040.5 Latest version!	Homo sapiens elongator acetyltransferase complex subunit 4 (ELP4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
View Old Accession Versions >>
OHu16081	NM_001288725.1	Homo sapiens elongator acetyltransferase complex subunit 4 (ELP4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu21125	NM_019040.4	Homo sapiens elongator acetyltransferase complex subunit 4 (ELP4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu16071	NM_001288726.1	Homo sapiens elongator acetyltransferase complex subunit 4 (ELP4), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ELP4 ( NM_001288726.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001275655.1 Homo sapiens elongator acetyltransferase complex subunit 4 (ELP4), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu16071
Clone ID Related Accession (Same CDS sequence)	NM_001288726.1 , NM_001288726.2
Accession Version	NM_001288726.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1608bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-29
Organism	Homo sapiens(human)
Product	elongator complex protein 4 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY127287.1, AK000505.1, BC012514.1, AC131571.4, BM680240.1, D59285.1, BF969161.1 and BQ083338.1. On Jan 1, 2014 this sequence version replaced XM_005252863.1. Transcript Variant: This variant (3) contains two alternate exon in the 3' coding region, which results in a frameshift, compared to variant 1. The encoded isoform (3) has a longer and distinct C-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC012514.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCAG TGGCAACCTG CGGTAGTGTT GCCGCGAGTA CTGGGTCTGC AGTGGCGACA 
GCCAGCAAGA GCAACGTCAC CAGTTTCCAG AGGAGGGGTC CTAGAGCCAG CGTGACCAAC 
GACAGCGGCC CTCGACTGGT GTCCATTGCG GGCACGCGAC CGTCGGTGCG GAATGGACAG 
CTGCTGGTAT CAACCGGGCT CCCAGCCCTA GACCAGCTCT TAGGTGGAGG TTTAGCCGTT 
GGAACAGTTC TTCTAATTGA GGAGGATAAA TATAATATTT ACTCACCTTT GCTCTTCAAG 
TATTTCCTGG CAGAAGGAAT TGTCAATGGG CATACTTTGT TGGTTGCATC TGCTAAAGAG 
GATCCTGCCA ACATTTTACA GGAACTTCCA GCACCATTAC TTGATGATAA ATGTAAAAAG 
GAATTTGATG AAGATGTATA CAATCATAAA ACACCAGAAT CTAATATTAA GATGAAAATA 
GCTTGGCGTT ACCAGTTATT ACCCAAGATG GAGATTGGAC CAGTATCATC TTCAAGATTT 
GGTCACTATT ATGATGCATC AAAAAGAATG CCACAAGAAC TAATTGAGGC TTCAAATTGG 
CATGGATTTT TTCTTCCAGA GAAAATATCT TCAACTCTCA AAGTAGAACC CTGTTCTTTG 
ACCCCTGGCT ACACAAAGCT GCTTCAGTTT ATCCAGAACA TCATTTATGA GGAAGGATTT 
GATGGATCCA ATCCTCAGAA AAAACAGAGA AACATTTTAA GAATAGGAAT TCAGAATCTT 
GGCTCACCTT TATGGGGAGA CGATATTTGC TGTGCAGAAA ATGGTGGCAA CAGTCACAGC 
CTTACCAAGT TCCTCTATGT TCTCCGTGGT CTTCTGAGAA CCTCTCTTTC AGCCTGCATC 
ATCACAATGC CAACACATCT GATCCAGAAT AAAGCCATTA TTGCCCGTGT CACAACCTTG 
TCAGATGTAG TAGTTGGTCT GGAATCATTT ATTGGTTCTG AGAGAGAAAC TAACCCATTG 
TATAAGGATT ATCATGGATT GATTCATATA CGGCAGATTC CTCGGCTTAA TAACTTGATC 
TGTGATGAAT CAGATGTCAA AGACTTAGCT TTTAAATTAA AAAGGAAGCT ATTCACCATT 
GAGGCTGGAG TGCAGTGGCA CGATCTCGGC TCACGGCAAC CTCGCCTCCT GGGTTCAAGC 
AATTCTCCCG CCTCAGCCTC CCTAGTAGCT GGGATTACAG GCGCCCACCA CCACACCCAG 
CTAATTTTTG TATTTTTAGT AGAGATGGGG TTCCACCATG TTGGCCAGGC TGGTCTCGAA 
CTCCTGACCT CAGGTGATTC ATCCGCCTCA GCCTCCCAAA GTGCTGGAAT TACAGGCATG 
AGCTACCGCG CCCGGCCTAG GGCTTTGTAT TTCAAAGAGA ACAAGTCTAA AGTGGGTGCA 
AGACAACTAC TTGAGACAAG AGAGGAACAT TTATCCTCCA GGCTTCTCAT ACTTACTCAA 
GCAGAAAGAC TCTGCATGGG GAGAAGGTTC TTTACAGCAT TCCACATTTT TAATGAGCTT 
CCTTGCAAAG GCGACTGCAT TTGCCTCCAG ACTTGTCAGA CACAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001275655.1
CDS	57..1664
Translation	MAAVATCGSVAASTGSAVATASKSNVTSFQRRGPRASVTNDSGPRLVSIAGTRPSVRNGQLLVSTGLPALDQLLGGGLAVGTVLLIEEDKYNIYSPLLFKYFLAEGIVNGHTLLVASAKEDPANILQELPAPLLDDKCKKEFDEDVYNHKTPESNIKMKIAWRYQLLPKMEIGPVSSSRFGHYYDASKRMPQELIEASNWHGFFLPEKISSTLKVEPCSLTPGYTKLLQFIQNIIYEEGFDGSNPQKKQRNILRIGIQNLGSPLWGDDICCAENGGNSHSLTKFLYVLRGLLRTSLSACIITMPTHLIQNKAIIARVTTLSDVVVGLESFIGSERETNPLYKDYHGLIHIRQIPRLNNLICDESDVKDLAFKLKRKLFTIEAGVQWHDLGSRQPRLLGSSNSPASASLVAGITGAHHHTQLIFVFLVEMGFHHVGQAGLELLTSGDSSASASQSAGITGMSYRARPRALYFKENKSKVGARQLLETREEHLSSRLLILTQAERLCMGRRFFTAFHIFNELPCKGDCICLQTCQTQ

Target ORF information:

RefSeq Version	NM_001288726.1
Organism	Homo sapiens(human)
Definition	Homo sapiens elongator acetyltransferase complex subunit 4 (ELP4), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001288726.1

ORF Insert Sequence:

ATGGCGGCAG TGGCAACCTG CGGTAGTGTT GCCGCGAGTA CTGGGTCTGC AGTGGCGACA 
GCCAGCAAGA GCAACGTCAC CAGTTTCCAG AGGAGGGGTC CTAGAGCCAG CGTGACCAAC 
GACAGCGGCC CTCGACTGGT GTCCATTGCG GGCACGCGAC CGTCGGTGCG GAATGGACAG 
CTGCTGGTAT CAACCGGGCT CCCAGCCCTA GACCAGCTCT TAGGTGGAGG TTTAGCCGTT 
GGAACAGTTC TTCTAATTGA GGAGGATAAA TATAATATTT ACTCACCTTT GCTCTTCAAG 
TATTTCCTGG CAGAAGGAAT TGTCAATGGG CATACTTTGT TGGTTGCATC TGCTAAAGAG 
GATCCTGCCA ACATTTTACA GGAACTTCCA GCACCATTAC TTGATGATAA ATGTAAAAAG 
GAATTTGATG AAGATGTATA CAATCATAAA ACACCAGAAT CTAATATTAA GATGAAAATA 
GCTTGGCGTT ACCAGTTATT ACCCAAGATG GAGATTGGAC CAGTATCATC TTCAAGATTT 
GGTCACTATT ATGATGCATC AAAAAGAATG CCACAAGAAC TAATTGAGGC TTCAAATTGG 
CATGGATTTT TTCTTCCAGA GAAAATATCT TCAACTCTCA AAGTAGAACC CTGTTCTTTG 
ACCCCTGGCT ACACAAAGCT GCTTCAGTTT ATCCAGAACA TCATTTATGA GGAAGGATTT 
GATGGATCCA ATCCTCAGAA AAAACAGAGA AACATTTTAA GAATAGGAAT TCAGAATCTT 
GGCTCACCTT TATGGGGAGA CGATATTTGC TGTGCAGAAA ATGGTGGCAA CAGTCACAGC 
CTTACCAAGT TCCTCTATGT TCTCCGTGGT CTTCTGAGAA CCTCTCTTTC AGCCTGCATC 
ATCACAATGC CAACACATCT GATCCAGAAT AAAGCCATTA TTGCCCGTGT CACAACCTTG 
TCAGATGTAG TAGTTGGTCT GGAATCATTT ATTGGTTCTG AGAGAGAAAC TAACCCATTG 
TATAAGGATT ATCATGGATT GATTCATATA CGGCAGATTC CTCGGCTTAA TAACTTGATC 
TGTGATGAAT CAGATGTCAA AGACTTAGCT TTTAAATTAA AAAGGAAGCT ATTCACCATT 
GAGGCTGGAG TGCAGTGGCA CGATCTCGGC TCACGGCAAC CTCGCCTCCT GGGTTCAAGC 
AATTCTCCCG CCTCAGCCTC CCTAGTAGCT GGGATTACAG GCGCCCACCA CCACACCCAG 
CTAATTTTTG TATTTTTAGT AGAGATGGGG TTCCACCATG TTGGCCAGGC TGGTCTCGAA 
CTCCTGACCT CAGGTGATTC ATCCGCCTCA GCCTCCCAAA GTGCTGGAAT TACAGGCATG 
AGCTACCGCG CCCGGCCTAG GGCTTTGTAT TTCAAAGAGA ACAAGTCTAA AGTGGGTGCA 
AGACAACTAC TTGAGACAAG AGAGGAACAT TTATCCTCCA GGCTTCTCAT ACTTACTCAA 
GCAGAAAGAC TCTGCATGGG GAGAAGGTTC TTTACAGCAT TCCACATTTT TAATGAGCTT 
CCTTGCAAAG GCGACTGCAT TTGCCTCCAG ACTTGTCAGA CACAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ELP4 ( NM_001288726.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001275655.1 Homo sapiens elongator acetyltransferase complex subunit 4 (ELP4), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu16071
Clone ID Related Accession (Same CDS sequence)	NM_001288726.1 , NM_001288726.2
Accession Version	NM_001288726.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1608bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-14
Organism	Homo sapiens(human)
Product	elongator complex protein 4 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK000505.1, BC012514.1, AC131571.4, BM680240.1, D59285.1, BF969161.1, BQ083338.1 and Z83307.1. On Jun 1, 2019 this sequence version replaced NM_001288726.1. Transcript Variant: This variant (3) contains two alternate exon in the 3' coding region, which results in a frameshift, compared to variant 1. The encoded isoform (3) has a longer and distinct C-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC012514.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCAG TGGCAACCTG CGGTAGTGTT GCCGCGAGTA CTGGGTCTGC AGTGGCGACA 
GCCAGCAAGA GCAACGTCAC CAGTTTCCAG AGGAGGGGTC CTAGAGCCAG CGTGACCAAC 
GACAGCGGCC CTCGACTGGT GTCCATTGCG GGCACGCGAC CGTCGGTGCG GAATGGACAG 
CTGCTGGTAT CAACCGGGCT CCCAGCCCTA GACCAGCTCT TAGGTGGAGG TTTAGCCGTT 
GGAACAGTTC TTCTAATTGA GGAGGATAAA TATAATATTT ACTCACCTTT GCTCTTCAAG 
TATTTCCTGG CAGAAGGAAT TGTCAATGGG CATACTTTGT TGGTTGCATC TGCTAAAGAG 
GATCCTGCCA ACATTTTACA GGAACTTCCA GCACCATTAC TTGATGATAA ATGTAAAAAG 
GAATTTGATG AAGATGTATA CAATCATAAA ACACCAGAAT CTAATATTAA GATGAAAATA 
GCTTGGCGTT ACCAGTTATT ACCCAAGATG GAGATTGGAC CAGTATCATC TTCAAGATTT 
GGTCACTATT ATGATGCATC AAAAAGAATG CCACAAGAAC TAATTGAGGC TTCAAATTGG 
CATGGATTTT TTCTTCCAGA GAAAATATCT TCAACTCTCA AAGTAGAACC CTGTTCTTTG 
ACCCCTGGCT ACACAAAGCT GCTTCAGTTT ATCCAGAACA TCATTTATGA GGAAGGATTT 
GATGGATCCA ATCCTCAGAA AAAACAGAGA AACATTTTAA GAATAGGAAT TCAGAATCTT 
GGCTCACCTT TATGGGGAGA CGATATTTGC TGTGCAGAAA ATGGTGGCAA CAGTCACAGC 
CTTACCAAGT TCCTCTATGT TCTCCGTGGT CTTCTGAGAA CCTCTCTTTC AGCCTGCATC 
ATCACAATGC CAACACATCT GATCCAGAAT AAAGCCATTA TTGCCCGTGT CACAACCTTG 
TCAGATGTAG TAGTTGGTCT GGAATCATTT ATTGGTTCTG AGAGAGAAAC TAACCCATTG 
TATAAGGATT ATCATGGATT GATTCATATA CGGCAGATTC CTCGGCTTAA TAACTTGATC 
TGTGATGAAT CAGATGTCAA AGACTTAGCT TTTAAATTAA AAAGGAAGCT ATTCACCATT 
GAGGCTGGAG TGCAGTGGCA CGATCTCGGC TCACGGCAAC CTCGCCTCCT GGGTTCAAGC 
AATTCTCCCG CCTCAGCCTC CCTAGTAGCT GGGATTACAG GCGCCCACCA CCACACCCAG 
CTAATTTTTG TATTTTTAGT AGAGATGGGG TTCCACCATG TTGGCCAGGC TGGTCTCGAA 
CTCCTGACCT CAGGTGATTC ATCCGCCTCA GCCTCCCAAA GTGCTGGAAT TACAGGCATG 
AGCTACCGCG CCCGGCCTAG GGCTTTGTAT TTCAAAGAGA ACAAGTCTAA AGTGGGTGCA 
AGACAACTAC TTGAGACAAG AGAGGAACAT TTATCCTCCA GGCTTCTCAT ACTTACTCAA 
GCAGAAAGAC TCTGCATGGG GAGAAGGTTC TTTACAGCAT TCCACATTTT TAATGAGCTT 
CCTTGCAAAG GCGACTGCAT TTGCCTCCAG ACTTGTCAGA CACAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001275655.1
CDS	19..1626
Translation	MAAVATCGSVAASTGSAVATASKSNVTSFQRRGPRASVTNDSGPRLVSIAGTRPSVRNGQLLVSTGLPALDQLLGGGLAVGTVLLIEEDKYNIYSPLLFKYFLAEGIVNGHTLLVASAKEDPANILQELPAPLLDDKCKKEFDEDVYNHKTPESNIKMKIAWRYQLLPKMEIGPVSSSRFGHYYDASKRMPQELIEASNWHGFFLPEKISSTLKVEPCSLTPGYTKLLQFIQNIIYEEGFDGSNPQKKQRNILRIGIQNLGSPLWGDDICCAENGGNSHSLTKFLYVLRGLLRTSLSACIITMPTHLIQNKAIIARVTTLSDVVVGLESFIGSERETNPLYKDYHGLIHIRQIPRLNNLICDESDVKDLAFKLKRKLFTIEAGVQWHDLGSRQPRLLGSSNSPASASLVAGITGAHHHTQLIFVFLVEMGFHHVGQAGLELLTSGDSSASASQSAGITGMSYRARPRALYFKENKSKVGARQLLETREEHLSSRLLILTQAERLCMGRRFFTAFHIFNELPCKGDCICLQTCQTQ

Target ORF information:

RefSeq Version	NM_001288726.2
Organism	Homo sapiens(human)
Definition	Homo sapiens elongator acetyltransferase complex subunit 4 (ELP4), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001288726.2

ORF Insert Sequence:

ATGGCGGCAG TGGCAACCTG CGGTAGTGTT GCCGCGAGTA CTGGGTCTGC AGTGGCGACA 
GCCAGCAAGA GCAACGTCAC CAGTTTCCAG AGGAGGGGTC CTAGAGCCAG CGTGACCAAC 
GACAGCGGCC CTCGACTGGT GTCCATTGCG GGCACGCGAC CGTCGGTGCG GAATGGACAG 
CTGCTGGTAT CAACCGGGCT CCCAGCCCTA GACCAGCTCT TAGGTGGAGG TTTAGCCGTT 
GGAACAGTTC TTCTAATTGA GGAGGATAAA TATAATATTT ACTCACCTTT GCTCTTCAAG 
TATTTCCTGG CAGAAGGAAT TGTCAATGGG CATACTTTGT TGGTTGCATC TGCTAAAGAG 
GATCCTGCCA ACATTTTACA GGAACTTCCA GCACCATTAC TTGATGATAA ATGTAAAAAG 
GAATTTGATG AAGATGTATA CAATCATAAA ACACCAGAAT CTAATATTAA GATGAAAATA 
GCTTGGCGTT ACCAGTTATT ACCCAAGATG GAGATTGGAC CAGTATCATC TTCAAGATTT 
GGTCACTATT ATGATGCATC AAAAAGAATG CCACAAGAAC TAATTGAGGC TTCAAATTGG 
CATGGATTTT TTCTTCCAGA GAAAATATCT TCAACTCTCA AAGTAGAACC CTGTTCTTTG 
ACCCCTGGCT ACACAAAGCT GCTTCAGTTT ATCCAGAACA TCATTTATGA GGAAGGATTT 
GATGGATCCA ATCCTCAGAA AAAACAGAGA AACATTTTAA GAATAGGAAT TCAGAATCTT 
GGCTCACCTT TATGGGGAGA CGATATTTGC TGTGCAGAAA ATGGTGGCAA CAGTCACAGC 
CTTACCAAGT TCCTCTATGT TCTCCGTGGT CTTCTGAGAA CCTCTCTTTC AGCCTGCATC 
ATCACAATGC CAACACATCT GATCCAGAAT AAAGCCATTA TTGCCCGTGT CACAACCTTG 
TCAGATGTAG TAGTTGGTCT GGAATCATTT ATTGGTTCTG AGAGAGAAAC TAACCCATTG 
TATAAGGATT ATCATGGATT GATTCATATA CGGCAGATTC CTCGGCTTAA TAACTTGATC 
TGTGATGAAT CAGATGTCAA AGACTTAGCT TTTAAATTAA AAAGGAAGCT ATTCACCATT 
GAGGCTGGAG TGCAGTGGCA CGATCTCGGC TCACGGCAAC CTCGCCTCCT GGGTTCAAGC 
AATTCTCCCG CCTCAGCCTC CCTAGTAGCT GGGATTACAG GCGCCCACCA CCACACCCAG 
CTAATTTTTG TATTTTTAGT AGAGATGGGG TTCCACCATG TTGGCCAGGC TGGTCTCGAA 
CTCCTGACCT CAGGTGATTC ATCCGCCTCA GCCTCCCAAA GTGCTGGAAT TACAGGCATG 
AGCTACCGCG CCCGGCCTAG GGCTTTGTAT TTCAAAGAGA ACAAGTCTAA AGTGGGTGCA 
AGACAACTAC TTGAGACAAG AGAGGAACAT TTATCCTCCA GGCTTCTCAT ACTTACTCAA 
GCAGAAAGAC TCTGCATGGG GAGAAGGTTC TTTACAGCAT TCCACATTTT TAATGAGCTT 
CCTTGCAAAG GCGACTGCAT TTGCCTCCAG ACTTGTCAGA CACAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ELP4 ( NM_001288725.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001275654.1 Homo sapiens elongator acetyltransferase complex subunit 4 (ELP4), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu16081
Clone ID Related Accession (Same CDS sequence)	NM_001288725.2 , NM_001288725.1
Accession Version	NM_001288725.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1431bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-14
Organism	Homo sapiens(human)
Product	elongator complex protein 4 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK000505.1, AK304885.1, AL136677.1, BM680240.1, D59285.1, BF969161.1, BQ083338.1 and Z83307.1. On May 31, 2019 this sequence version replaced NM_001288725.1. Transcript Variant: This variant (2) contains an alternate exon in the 3' coding region, which results in a frameshift, compared to variant 1. The encoded isoform (2) has a longer and distinct C-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK304885.1, SRR1803612.474356.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2152719 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCAG TGGCAACCTG CGGTAGTGTT GCCGCGAGTA CTGGGTCTGC AGTGGCGACA 
GCCAGCAAGA GCAACGTCAC CAGTTTCCAG AGGAGGGGTC CTAGAGCCAG CGTGACCAAC 
GACAGCGGCC CTCGACTGGT GTCCATTGCG GGCACGCGAC CGTCGGTGCG GAATGGACAG 
CTGCTGGTAT CAACCGGGCT CCCAGCCCTA GACCAGCTCT TAGGTGGAGG TTTAGCCGTT 
GGAACAGTTC TTCTAATTGA GGAGGATAAA TATAATATTT ACTCACCTTT GCTCTTCAAG 
TATTTCCTGG CAGAAGGAAT TGTCAATGGG CATACTTTGT TGGTTGCATC TGCTAAAGAG 
GATCCTGCCA ACATTTTACA GGAACTTCCA GCACCATTAC TTGATGATAA ATGTAAAAAG 
GAATTTGATG AAGATGTATA CAATCATAAA ACACCAGAAT CTAATATTAA GATGAAAATA 
GCTTGGCGTT ACCAGTTATT ACCCAAGATG GAGCAGATTG GACCAGTATC ATCTTCAAGA 
TTTGGTCACT ATTATGATGC ATCAAAAAGA ATGCCACAAG AACTAATTGA GGCTTCAAAT 
TGGCATGGAT TTTTTCTTCC AGAGAAAATA TCTTCAACTC TCAAAGTAGA ACCCTGTTCT 
TTGACCCCTG GCTACACAAA GCTGCTTCAG TTTATCCAGA ACATCATTTA TGAGGAAGGA 
TTTGATGGAT CCAATCCTCA GAAAAAACAG AGAAACATTT TAAGAATAGG AATTCAGAAT 
CTTGGCTCAC CTTTATGGGG AGACGATATT TGCTGTGCAG AAAATGGTGG CAACAGTCAC 
AGCCTTACCA AGTTCCTCTA TGTTCTCCGT GGTCTTCTGA GAACCTCTCT TTCAGCCTGC 
ATCATCACAA TGCCAACACA TCTGATCCAG AATAAAGCCA TTATTGCCCG TGTCACAACC 
TTGTCAGATG TAGTAGTTGG TCTGGAATCA TTTATTGGTT CTGAGAGAGA AACTAACCCA 
TTGTATAAGG ATTATCATGG ATTGATTCAT ATACGGCAGA TTCCTCGGCT TAATAACTTG 
ATCTGTGATG AATCAGATGT CAAAGACTTA GCTTTTAAAT TAAAAAGGAA GCTATTCACC 
ATTGAGTGGG TGCAAGACAA CTACTTGAGA CAAGAGAGGA ACATTTATCC TCCAGGCTTC 
TCATACTTAC TCAAGCAGAA AGACTCTGCA TGGGGAGAAG GTTCTTTACA GCATTCCACA 
TTTTTAATGA GCTTCCTTGC AAAGGCGACT GCATTTGCCT CCAGACTTGT CAGACACAGT 
GAGCCGCTCA AGCAAAATGG ATCTGGCAGA ATCCGCCAAG CGGCTGGGCC CAGGCTGTGG 
CATGATGGCC GGAGGCAAGA AGCACCTGGA CTTCTAGGGA TTCCTCCTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001275654.1
CDS	19..1449
Translation	MAAVATCGSVAASTGSAVATASKSNVTSFQRRGPRASVTNDSGPRLVSIAGTRPSVRNGQLLVSTGLPALDQLLGGGLAVGTVLLIEEDKYNIYSPLLFKYFLAEGIVNGHTLLVASAKEDPANILQELPAPLLDDKCKKEFDEDVYNHKTPESNIKMKIAWRYQLLPKMEQIGPVSSSRFGHYYDASKRMPQELIEASNWHGFFLPEKISSTLKVEPCSLTPGYTKLLQFIQNIIYEEGFDGSNPQKKQRNILRIGIQNLGSPLWGDDICCAENGGNSHSLTKFLYVLRGLLRTSLSACIITMPTHLIQNKAIIARVTTLSDVVVGLESFIGSERETNPLYKDYHGLIHIRQIPRLNNLICDESDVKDLAFKLKRKLFTIEWVQDNYLRQERNIYPPGFSYLLKQKDSAWGEGSLQHSTFLMSFLAKATAFASRLVRHSEPLKQNGSGRIRQAAGPRLWHDGRRQEAPGLLGIPP

Target ORF information:

RefSeq Version	NM_001288725.2
Organism	Homo sapiens(human)
Definition	Homo sapiens elongator acetyltransferase complex subunit 4 (ELP4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001288725.2

ORF Insert Sequence:

ATGGCGGCAG TGGCAACCTG CGGTAGTGTT GCCGCGAGTA CTGGGTCTGC AGTGGCGACA 
GCCAGCAAGA GCAACGTCAC CAGTTTCCAG AGGAGGGGTC CTAGAGCCAG CGTGACCAAC 
GACAGCGGCC CTCGACTGGT GTCCATTGCG GGCACGCGAC CGTCGGTGCG GAATGGACAG 
CTGCTGGTAT CAACCGGGCT CCCAGCCCTA GACCAGCTCT TAGGTGGAGG TTTAGCCGTT 
GGAACAGTTC TTCTAATTGA GGAGGATAAA TATAATATTT ACTCACCTTT GCTCTTCAAG 
TATTTCCTGG CAGAAGGAAT TGTCAATGGG CATACTTTGT TGGTTGCATC TGCTAAAGAG 
GATCCTGCCA ACATTTTACA GGAACTTCCA GCACCATTAC TTGATGATAA ATGTAAAAAG 
GAATTTGATG AAGATGTATA CAATCATAAA ACACCAGAAT CTAATATTAA GATGAAAATA 
GCTTGGCGTT ACCAGTTATT ACCCAAGATG GAGCAGATTG GACCAGTATC ATCTTCAAGA 
TTTGGTCACT ATTATGATGC ATCAAAAAGA ATGCCACAAG AACTAATTGA GGCTTCAAAT 
TGGCATGGAT TTTTTCTTCC AGAGAAAATA TCTTCAACTC TCAAAGTAGA ACCCTGTTCT 
TTGACCCCTG GCTACACAAA GCTGCTTCAG TTTATCCAGA ACATCATTTA TGAGGAAGGA 
TTTGATGGAT CCAATCCTCA GAAAAAACAG AGAAACATTT TAAGAATAGG AATTCAGAAT 
CTTGGCTCAC CTTTATGGGG AGACGATATT TGCTGTGCAG AAAATGGTGG CAACAGTCAC 
AGCCTTACCA AGTTCCTCTA TGTTCTCCGT GGTCTTCTGA GAACCTCTCT TTCAGCCTGC 
ATCATCACAA TGCCAACACA TCTGATCCAG AATAAAGCCA TTATTGCCCG TGTCACAACC 
TTGTCAGATG TAGTAGTTGG TCTGGAATCA TTTATTGGTT CTGAGAGAGA AACTAACCCA 
TTGTATAAGG ATTATCATGG ATTGATTCAT ATACGGCAGA TTCCTCGGCT TAATAACTTG 
ATCTGTGATG AATCAGATGT CAAAGACTTA GCTTTTAAAT TAAAAAGGAA GCTATTCACC 
ATTGAGTGGG TGCAAGACAA CTACTTGAGA CAAGAGAGGA ACATTTATCC TCCAGGCTTC 
TCATACTTAC TCAAGCAGAA AGACTCTGCA TGGGGAGAAG GTTCTTTACA GCATTCCACA 
TTTTTAATGA GCTTCCTTGC AAAGGCGACT GCATTTGCCT CCAGACTTGT CAGACACAGT 
GAGCCGCTCA AGCAAAATGG ATCTGGCAGA ATCCGCCAAG CGGCTGGGCC CAGGCTGTGG 
CATGATGGCC GGAGGCAAGA AGCACCTGGA CTTCTAGGGA TTCCTCCTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ELP4 ( NM_001288725.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001275654.1 Homo sapiens elongator acetyltransferase complex subunit 4 (ELP4), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu16081
Clone ID Related Accession (Same CDS sequence)	NM_001288725.2 , NM_001288725.1
Accession Version	NM_001288725.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1431bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-29
Organism	Homo sapiens(human)
Product	elongator complex protein 4 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY127287.1, AK000505.1, AK304885.1, AL136677.1, BM680240.1, D59285.1, BF969161.1 and BQ083338.1. On Jan 1, 2014 this sequence version replaced XM_005252864.1. Transcript Variant: This variant (2) contains an alternate exon in the 3' coding region, which results in a frameshift, compared to variant 1. The encoded isoform (2) has a longer and distinct C-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK304885.1, SRR1803612.474356.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2152719 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCAG TGGCAACCTG CGGTAGTGTT GCCGCGAGTA CTGGGTCTGC AGTGGCGACA 
GCCAGCAAGA GCAACGTCAC CAGTTTCCAG AGGAGGGGTC CTAGAGCCAG CGTGACCAAC 
GACAGCGGCC CTCGACTGGT GTCCATTGCG GGCACGCGAC CGTCGGTGCG GAATGGACAG 
CTGCTGGTAT CAACCGGGCT CCCAGCCCTA GACCAGCTCT TAGGTGGAGG TTTAGCCGTT 
GGAACAGTTC TTCTAATTGA GGAGGATAAA TATAATATTT ACTCACCTTT GCTCTTCAAG 
TATTTCCTGG CAGAAGGAAT TGTCAATGGG CATACTTTGT TGGTTGCATC TGCTAAAGAG 
GATCCTGCCA ACATTTTACA GGAACTTCCA GCACCATTAC TTGATGATAA ATGTAAAAAG 
GAATTTGATG AAGATGTATA CAATCATAAA ACACCAGAAT CTAATATTAA GATGAAAATA 
GCTTGGCGTT ACCAGTTATT ACCCAAGATG GAGCAGATTG GACCAGTATC ATCTTCAAGA 
TTTGGTCACT ATTATGATGC ATCAAAAAGA ATGCCACAAG AACTAATTGA GGCTTCAAAT 
TGGCATGGAT TTTTTCTTCC AGAGAAAATA TCTTCAACTC TCAAAGTAGA ACCCTGTTCT 
TTGACCCCTG GCTACACAAA GCTGCTTCAG TTTATCCAGA ACATCATTTA TGAGGAAGGA 
TTTGATGGAT CCAATCCTCA GAAAAAACAG AGAAACATTT TAAGAATAGG AATTCAGAAT 
CTTGGCTCAC CTTTATGGGG AGACGATATT TGCTGTGCAG AAAATGGTGG CAACAGTCAC 
AGCCTTACCA AGTTCCTCTA TGTTCTCCGT GGTCTTCTGA GAACCTCTCT TTCAGCCTGC 
ATCATCACAA TGCCAACACA TCTGATCCAG AATAAAGCCA TTATTGCCCG TGTCACAACC 
TTGTCAGATG TAGTAGTTGG TCTGGAATCA TTTATTGGTT CTGAGAGAGA AACTAACCCA 
TTGTATAAGG ATTATCATGG ATTGATTCAT ATACGGCAGA TTCCTCGGCT TAATAACTTG 
ATCTGTGATG AATCAGATGT CAAAGACTTA GCTTTTAAAT TAAAAAGGAA GCTATTCACC 
ATTGAGTGGG TGCAAGACAA CTACTTGAGA CAAGAGAGGA ACATTTATCC TCCAGGCTTC 
TCATACTTAC TCAAGCAGAA AGACTCTGCA TGGGGAGAAG GTTCTTTACA GCATTCCACA 
TTTTTAATGA GCTTCCTTGC AAAGGCGACT GCATTTGCCT CCAGACTTGT CAGACACAGT 
GAGCCGCTCA AGCAAAATGG ATCTGGCAGA ATCCGCCAAG CGGCTGGGCC CAGGCTGTGG 
CATGATGGCC GGAGGCAAGA AGCACCTGGA CTTCTAGGGA TTCCTCCTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001275654.1
CDS	57..1487
Translation	MAAVATCGSVAASTGSAVATASKSNVTSFQRRGPRASVTNDSGPRLVSIAGTRPSVRNGQLLVSTGLPALDQLLGGGLAVGTVLLIEEDKYNIYSPLLFKYFLAEGIVNGHTLLVASAKEDPANILQELPAPLLDDKCKKEFDEDVYNHKTPESNIKMKIAWRYQLLPKMEQIGPVSSSRFGHYYDASKRMPQELIEASNWHGFFLPEKISSTLKVEPCSLTPGYTKLLQFIQNIIYEEGFDGSNPQKKQRNILRIGIQNLGSPLWGDDICCAENGGNSHSLTKFLYVLRGLLRTSLSACIITMPTHLIQNKAIIARVTTLSDVVVGLESFIGSERETNPLYKDYHGLIHIRQIPRLNNLICDESDVKDLAFKLKRKLFTIEWVQDNYLRQERNIYPPGFSYLLKQKDSAWGEGSLQHSTFLMSFLAKATAFASRLVRHSEPLKQNGSGRIRQAAGPRLWHDGRRQEAPGLLGIPP

Target ORF information:

RefSeq Version	NM_001288725.1
Organism	Homo sapiens(human)
Definition	Homo sapiens elongator acetyltransferase complex subunit 4 (ELP4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001288725.1

ORF Insert Sequence:

ATGGCGGCAG TGGCAACCTG CGGTAGTGTT GCCGCGAGTA CTGGGTCTGC AGTGGCGACA 
GCCAGCAAGA GCAACGTCAC CAGTTTCCAG AGGAGGGGTC CTAGAGCCAG CGTGACCAAC 
GACAGCGGCC CTCGACTGGT GTCCATTGCG GGCACGCGAC CGTCGGTGCG GAATGGACAG 
CTGCTGGTAT CAACCGGGCT CCCAGCCCTA GACCAGCTCT TAGGTGGAGG TTTAGCCGTT 
GGAACAGTTC TTCTAATTGA GGAGGATAAA TATAATATTT ACTCACCTTT GCTCTTCAAG 
TATTTCCTGG CAGAAGGAAT TGTCAATGGG CATACTTTGT TGGTTGCATC TGCTAAAGAG 
GATCCTGCCA ACATTTTACA GGAACTTCCA GCACCATTAC TTGATGATAA ATGTAAAAAG 
GAATTTGATG AAGATGTATA CAATCATAAA ACACCAGAAT CTAATATTAA GATGAAAATA 
GCTTGGCGTT ACCAGTTATT ACCCAAGATG GAGCAGATTG GACCAGTATC ATCTTCAAGA 
TTTGGTCACT ATTATGATGC ATCAAAAAGA ATGCCACAAG AACTAATTGA GGCTTCAAAT 
TGGCATGGAT TTTTTCTTCC AGAGAAAATA TCTTCAACTC TCAAAGTAGA ACCCTGTTCT 
TTGACCCCTG GCTACACAAA GCTGCTTCAG TTTATCCAGA ACATCATTTA TGAGGAAGGA 
TTTGATGGAT CCAATCCTCA GAAAAAACAG AGAAACATTT TAAGAATAGG AATTCAGAAT 
CTTGGCTCAC CTTTATGGGG AGACGATATT TGCTGTGCAG AAAATGGTGG CAACAGTCAC 
AGCCTTACCA AGTTCCTCTA TGTTCTCCGT GGTCTTCTGA GAACCTCTCT TTCAGCCTGC 
ATCATCACAA TGCCAACACA TCTGATCCAG AATAAAGCCA TTATTGCCCG TGTCACAACC 
TTGTCAGATG TAGTAGTTGG TCTGGAATCA TTTATTGGTT CTGAGAGAGA AACTAACCCA 
TTGTATAAGG ATTATCATGG ATTGATTCAT ATACGGCAGA TTCCTCGGCT TAATAACTTG 
ATCTGTGATG AATCAGATGT CAAAGACTTA GCTTTTAAAT TAAAAAGGAA GCTATTCACC 
ATTGAGTGGG TGCAAGACAA CTACTTGAGA CAAGAGAGGA ACATTTATCC TCCAGGCTTC 
TCATACTTAC TCAAGCAGAA AGACTCTGCA TGGGGAGAAG GTTCTTTACA GCATTCCACA 
TTTTTAATGA GCTTCCTTGC AAAGGCGACT GCATTTGCCT CCAGACTTGT CAGACACAGT 
GAGCCGCTCA AGCAAAATGG ATCTGGCAGA ATCCGCCAAG CGGCTGGGCC CAGGCTGTGG 
CATGATGGCC GGAGGCAAGA AGCACCTGGA CTTCTAGGGA TTCCTCCTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ELP4 ( NM_019040.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_061913.3 Homo sapiens elongator acetyltransferase complex subunit 4 (ELP4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu21125
Clone ID Related Accession (Same CDS sequence)	NM_019040.5 , NM_019040.4
Accession Version	NM_019040.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1275bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-21
Organism	Homo sapiens(human)
Product	elongator complex protein 4 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK000505.1, BM680240.1, D59285.1, BF969161.1, BQ083338.1 and Z83307.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_019040.4. Transcript Variant: This variant (1) represents the shortest transcript and encodes the shortest protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.26083.1, SRR1660803.84621.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000640961.2/ ENSP00000492152.1 RefSeq Select criteria :: based on expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGCAG TGGCAACCTG CGGTAGTGTT GCCGCGAGTA CTGGGTCTGC AGTGGCGACA 
GCCAGCAAGA GCAACGTCAC CAGTTTCCAG AGGAGGGGTC CTAGAGCCAG CGTGACCAAC 
GACAGCGGCC CTCGACTGGT GTCCATTGCG GGCACGCGAC CGTCGGTGCG GAATGGACAG 
CTGCTGGTAT CAACCGGGCT CCCAGCCCTA GACCAGCTCT TAGGTGGAGG TTTAGCCGTT 
GGAACAGTTC TTCTAATTGA GGAGGATAAA TATAATATTT ACTCACCTTT GCTCTTCAAG 
TATTTCCTGG CAGAAGGAAT TGTCAATGGG CATACTTTGT TGGTTGCATC TGCTAAAGAG 
GATCCTGCCA ACATTTTACA GGAACTTCCA GCACCATTAC TTGATGATAA ATGTAAAAAG 
GAATTTGATG AAGATGTATA CAATCATAAA ACACCAGAAT CTAATATTAA GATGAAAATA 
GCTTGGCGTT ACCAGTTATT ACCCAAGATG GAGATTGGAC CAGTATCATC TTCAAGATTT 
GGTCACTATT ATGATGCATC AAAAAGAATG CCACAAGAAC TAATTGAGGC TTCAAATTGG 
CATGGATTTT TTCTTCCAGA GAAAATATCT TCAACTCTCA AAGTAGAACC CTGTTCTTTG 
ACCCCTGGCT ACACAAAGCT GCTTCAGTTT ATCCAGAACA TCATTTATGA GGAAGGATTT 
GATGGATCCA ATCCTCAGAA AAAACAGAGA AACATTTTAA GAATAGGAAT TCAGAATCTT 
GGCTCACCTT TATGGGGAGA CGATATTTGC TGTGCAGAAA ATGGTGGCAA CAGTCACAGC 
CTTACCAAGT TCCTCTATGT TCTCCGTGGT CTTCTGAGAA CCTCTCTTTC AGCCTGCATC 
ATCACAATGC CAACACATCT GATCCAGAAT AAAGCCATTA TTGCCCGTGT CACAACCTTG 
TCAGATGTAG TAGTTGGTCT GGAATCATTT ATTGGTTCTG AGAGAGAAAC TAACCCATTG 
TATAAGGATT ATCATGGATT GATTCATATA CGGCAGATTC CTCGGCTTAA TAACTTGATC 
TGTGATGAAT CAGATGTCAA AGACTTAGCT TTTAAATTAA AAAGGAAGCT ATTCACCATT 
GAGCGACTGC ATTTGCCTCC AGACTTGTCA GACACAGTGA GCCGCTCAAG CAAAATGGAT 
CTGGCAGAAT CCGCCAAGCG GCTGGGCCCA GGCTGTGGCA TGATGGCCGG AGGCAAGAAG 
CACCTGGACT TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061913.3
CDS	19..1293
Translation	MAAVATCGSVAASTGSAVATASKSNVTSFQRRGPRASVTNDSGPRLVSIAGTRPSVRNGQLLVSTGLPALDQLLGGGLAVGTVLLIEEDKYNIYSPLLFKYFLAEGIVNGHTLLVASAKEDPANILQELPAPLLDDKCKKEFDEDVYNHKTPESNIKMKIAWRYQLLPKMEIGPVSSSRFGHYYDASKRMPQELIEASNWHGFFLPEKISSTLKVEPCSLTPGYTKLLQFIQNIIYEEGFDGSNPQKKQRNILRIGIQNLGSPLWGDDICCAENGGNSHSLTKFLYVLRGLLRTSLSACIITMPTHLIQNKAIIARVTTLSDVVVGLESFIGSERETNPLYKDYHGLIHIRQIPRLNNLICDESDVKDLAFKLKRKLFTIERLHLPPDLSDTVSRSSKMDLAESAKRLGPGCGMMAGGKKHLDF

Target ORF information:

RefSeq Version	NM_019040.5
Organism	Homo sapiens(human)
Definition	Homo sapiens elongator acetyltransferase complex subunit 4 (ELP4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019040.5

ORF Insert Sequence:

ATGGCGGCAG TGGCAACCTG CGGTAGTGTT GCCGCGAGTA CTGGGTCTGC AGTGGCGACA 
GCCAGCAAGA GCAACGTCAC CAGTTTCCAG AGGAGGGGTC CTAGAGCCAG CGTGACCAAC 
GACAGCGGCC CTCGACTGGT GTCCATTGCG GGCACGCGAC CGTCGGTGCG GAATGGACAG 
CTGCTGGTAT CAACCGGGCT CCCAGCCCTA GACCAGCTCT TAGGTGGAGG TTTAGCCGTT 
GGAACAGTTC TTCTAATTGA GGAGGATAAA TATAATATTT ACTCACCTTT GCTCTTCAAG 
TATTTCCTGG CAGAAGGAAT TGTCAATGGG CATACTTTGT TGGTTGCATC TGCTAAAGAG 
GATCCTGCCA ACATTTTACA GGAACTTCCA GCACCATTAC TTGATGATAA ATGTAAAAAG 
GAATTTGATG AAGATGTATA CAATCATAAA ACACCAGAAT CTAATATTAA GATGAAAATA 
GCTTGGCGTT ACCAGTTATT ACCCAAGATG GAGATTGGAC CAGTATCATC TTCAAGATTT 
GGTCACTATT ATGATGCATC AAAAAGAATG CCACAAGAAC TAATTGAGGC TTCAAATTGG 
CATGGATTTT TTCTTCCAGA GAAAATATCT TCAACTCTCA AAGTAGAACC CTGTTCTTTG 
ACCCCTGGCT ACACAAAGCT GCTTCAGTTT ATCCAGAACA TCATTTATGA GGAAGGATTT 
GATGGATCCA ATCCTCAGAA AAAACAGAGA AACATTTTAA GAATAGGAAT TCAGAATCTT 
GGCTCACCTT TATGGGGAGA CGATATTTGC TGTGCAGAAA ATGGTGGCAA CAGTCACAGC 
CTTACCAAGT TCCTCTATGT TCTCCGTGGT CTTCTGAGAA CCTCTCTTTC AGCCTGCATC 
ATCACAATGC CAACACATCT GATCCAGAAT AAAGCCATTA TTGCCCGTGT CACAACCTTG 
TCAGATGTAG TAGTTGGTCT GGAATCATTT ATTGGTTCTG AGAGAGAAAC TAACCCATTG 
TATAAGGATT ATCATGGATT GATTCATATA CGGCAGATTC CTCGGCTTAA TAACTTGATC 
TGTGATGAAT CAGATGTCAA AGACTTAGCT TTTAAATTAA AAAGGAAGCT ATTCACCATT 
GAGCGACTGC ATTTGCCTCC AGACTTGTCA GACACAGTGA GCCGCTCAAG CAAAATGGAT 
CTGGCAGAAT CCGCCAAGCG GCTGGGCCCA GGCTGTGGCA TGATGGCCGG AGGCAAGAAG 
CACCTGGACT TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ELP4 ( NM_019040.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_061913.3 Homo sapiens elongator acetyltransferase complex subunit 4 (ELP4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu21125
Clone ID Related Accession (Same CDS sequence)	NM_019040.5 , NM_019040.4
Accession Version	NM_019040.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1275bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-27
Organism	Homo sapiens(human)
Product	elongator complex protein 4 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY127287.1, AK000505.1, BM680240.1, D59285.1, BF969161.1 and BQ083338.1. This sequence is a reference standard in the RefSeqGene project. On Jan 1, 2014 this sequence version replaced NM_019040.3. Transcript Variant: This variant (1) represents the shortest transcript and encodes the shortest protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.205842.1, SRR1803616.122224.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCAG TGGCAACCTG CGGTAGTGTT GCCGCGAGTA CTGGGTCTGC AGTGGCGACA 
GCCAGCAAGA GCAACGTCAC CAGTTTCCAG AGGAGGGGTC CTAGAGCCAG CGTGACCAAC 
GACAGCGGCC CTCGACTGGT GTCCATTGCG GGCACGCGAC CGTCGGTGCG GAATGGACAG 
CTGCTGGTAT CAACCGGGCT CCCAGCCCTA GACCAGCTCT TAGGTGGAGG TTTAGCCGTT 
GGAACAGTTC TTCTAATTGA GGAGGATAAA TATAATATTT ACTCACCTTT GCTCTTCAAG 
TATTTCCTGG CAGAAGGAAT TGTCAATGGG CATACTTTGT TGGTTGCATC TGCTAAAGAG 
GATCCTGCCA ACATTTTACA GGAACTTCCA GCACCATTAC TTGATGATAA ATGTAAAAAG 
GAATTTGATG AAGATGTATA CAATCATAAA ACACCAGAAT CTAATATTAA GATGAAAATA 
GCTTGGCGTT ACCAGTTATT ACCCAAGATG GAGATTGGAC CAGTATCATC TTCAAGATTT 
GGTCACTATT ATGATGCATC AAAAAGAATG CCACAAGAAC TAATTGAGGC TTCAAATTGG 
CATGGATTTT TTCTTCCAGA GAAAATATCT TCAACTCTCA AAGTAGAACC CTGTTCTTTG 
ACCCCTGGCT ACACAAAGCT GCTTCAGTTT ATCCAGAACA TCATTTATGA GGAAGGATTT 
GATGGATCCA ATCCTCAGAA AAAACAGAGA AACATTTTAA GAATAGGAAT TCAGAATCTT 
GGCTCACCTT TATGGGGAGA CGATATTTGC TGTGCAGAAA ATGGTGGCAA CAGTCACAGC 
CTTACCAAGT TCCTCTATGT TCTCCGTGGT CTTCTGAGAA CCTCTCTTTC AGCCTGCATC 
ATCACAATGC CAACACATCT GATCCAGAAT AAAGCCATTA TTGCCCGTGT CACAACCTTG 
TCAGATGTAG TAGTTGGTCT GGAATCATTT ATTGGTTCTG AGAGAGAAAC TAACCCATTG 
TATAAGGATT ATCATGGATT GATTCATATA CGGCAGATTC CTCGGCTTAA TAACTTGATC 
TGTGATGAAT CAGATGTCAA AGACTTAGCT TTTAAATTAA AAAGGAAGCT ATTCACCATT 
GAGCGACTGC ATTTGCCTCC AGACTTGTCA GACACAGTGA GCCGCTCAAG CAAAATGGAT 
CTGGCAGAAT CCGCCAAGCG GCTGGGCCCA GGCTGTGGCA TGATGGCCGG AGGCAAGAAG 
CACCTGGACT TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061913.3
CDS	57..1331
Translation	MAAVATCGSVAASTGSAVATASKSNVTSFQRRGPRASVTNDSGPRLVSIAGTRPSVRNGQLLVSTGLPALDQLLGGGLAVGTVLLIEEDKYNIYSPLLFKYFLAEGIVNGHTLLVASAKEDPANILQELPAPLLDDKCKKEFDEDVYNHKTPESNIKMKIAWRYQLLPKMEIGPVSSSRFGHYYDASKRMPQELIEASNWHGFFLPEKISSTLKVEPCSLTPGYTKLLQFIQNIIYEEGFDGSNPQKKQRNILRIGIQNLGSPLWGDDICCAENGGNSHSLTKFLYVLRGLLRTSLSACIITMPTHLIQNKAIIARVTTLSDVVVGLESFIGSERETNPLYKDYHGLIHIRQIPRLNNLICDESDVKDLAFKLKRKLFTIERLHLPPDLSDTVSRSSKMDLAESAKRLGPGCGMMAGGKKHLDF

Target ORF information:

RefSeq Version	NM_019040.4
Organism	Homo sapiens(human)
Definition	Homo sapiens elongator acetyltransferase complex subunit 4 (ELP4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019040.4

ORF Insert Sequence:

ATGGCGGCAG TGGCAACCTG CGGTAGTGTT GCCGCGAGTA CTGGGTCTGC AGTGGCGACA 
GCCAGCAAGA GCAACGTCAC CAGTTTCCAG AGGAGGGGTC CTAGAGCCAG CGTGACCAAC 
GACAGCGGCC CTCGACTGGT GTCCATTGCG GGCACGCGAC CGTCGGTGCG GAATGGACAG 
CTGCTGGTAT CAACCGGGCT CCCAGCCCTA GACCAGCTCT TAGGTGGAGG TTTAGCCGTT 
GGAACAGTTC TTCTAATTGA GGAGGATAAA TATAATATTT ACTCACCTTT GCTCTTCAAG 
TATTTCCTGG CAGAAGGAAT TGTCAATGGG CATACTTTGT TGGTTGCATC TGCTAAAGAG 
GATCCTGCCA ACATTTTACA GGAACTTCCA GCACCATTAC TTGATGATAA ATGTAAAAAG 
GAATTTGATG AAGATGTATA CAATCATAAA ACACCAGAAT CTAATATTAA GATGAAAATA 
GCTTGGCGTT ACCAGTTATT ACCCAAGATG GAGATTGGAC CAGTATCATC TTCAAGATTT 
GGTCACTATT ATGATGCATC AAAAAGAATG CCACAAGAAC TAATTGAGGC TTCAAATTGG 
CATGGATTTT TTCTTCCAGA GAAAATATCT TCAACTCTCA AAGTAGAACC CTGTTCTTTG 
ACCCCTGGCT ACACAAAGCT GCTTCAGTTT ATCCAGAACA TCATTTATGA GGAAGGATTT 
GATGGATCCA ATCCTCAGAA AAAACAGAGA AACATTTTAA GAATAGGAAT TCAGAATCTT 
GGCTCACCTT TATGGGGAGA CGATATTTGC TGTGCAGAAA ATGGTGGCAA CAGTCACAGC 
CTTACCAAGT TCCTCTATGT TCTCCGTGGT CTTCTGAGAA CCTCTCTTTC AGCCTGCATC 
ATCACAATGC CAACACATCT GATCCAGAAT AAAGCCATTA TTGCCCGTGT CACAACCTTG 
TCAGATGTAG TAGTTGGTCT GGAATCATTT ATTGGTTCTG AGAGAGAAAC TAACCCATTG 
TATAAGGATT ATCATGGATT GATTCATATA CGGCAGATTC CTCGGCTTAA TAACTTGATC 
TGTGATGAAT CAGATGTCAA AGACTTAGCT TTTAAATTAA AAAGGAAGCT ATTCACCATT 
GAGCGACTGC ATTTGCCTCC AGACTTGTCA GACACAGTGA GCCGCTCAAG CAAAATGGAT 
CTGGCAGAAT CCGCCAAGCG GCTGGGCCCA GGCTGTGGCA TGATGGCCGG AGGCAAGAAG 
CACCTGGACT TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Microdeletions of ELP4 Are Associated with Language Impairment, Autism Spectrum Disorder, and Mental Retardation.
Human mutation36(9)842-50(2015 Sep)
Addis L,Ahn JW,Dobson R,Dixit A,Ogilvie CM,Pinto D,Vaags AK,Coon H,Chaste P,Wilson S,Parr JR,Andrieux J,Lenne B,Tumer Z,Leuzzi V,Aubell K,Koillinen H,Curran S,Marshall CR,Scherer SW,Strug LJ,Collier DA,Pal DK

Association of brain-derived neurotrophic factor (BDNF) and elongator protein complex 4 (ELP4) polymorphisms with benign epilepsy with centrotemporal spikes in a Greek population.
Epilepsy research108(10)1734-9(2014 Dec)
Gkampeta A,Fidani L,Clarim?n J,Kalinderi K,Katopodi T,Zafeiriou D,Pavlou E

Genome-wide association and admixture analysis of glaucoma in the Women's Health Initiative.
Human molecular genetics23(24)6634-43(2014 Dec)
Hoffmann TJ,Tang H,Thornton TA,Caan B,Haan M,Millen AE,Thomas F,Risch N

Analysis of ELP4, SRPX2, and interacting genes in typical and atypical rolandic epilepsy.
Epilepsia55(8)e89-93(2014 Aug)
Reinthaler EM,Lal D,Jurkowski W,Feucht M,Steinb?ck H,Gruber-Sedlmayr U,Ronen GM,Geldner J,Haberlandt E,Neophytou B,Hahn A,Altm?ller J,Thiele H,Toliat MR,,Lerche H,N?rnberg P,Sander T,Neubauer BA,Zimprich F

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ELP4 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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