GREM1 gene cDNA ORF clone, Homo sapiens(human)

mRNA	Protein	Name
XM_017022077.1	XP_016877566.1	gremlin-1 isoform X1
NM_001191323.1	NP_001178252.1	gremlin-1 isoform 2 precursor
XM_005254301.2	XP_005254358.1	gremlin-1 isoform X1
NM_001191323.2	NP_001178252.1	gremlin-1 isoform 2 precursor
NM_001191322.1	NP_001178251.1	gremlin-1 isoform 3
NM_013372.6	NP_037504.1	gremlin-1 isoform 1 precursor
NM_001368719.1	NP_001355648.1	gremlin-1 isoform 1 precursor
NM_013372.7	NP_037504.1	gremlin-1 isoform 1 precursor
NM_001191322.2	NP_001178251.1	gremlin-1 isoform 3

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu23108	NM_013372.7 Latest version!	Homo sapiens gremlin 1, DAN family BMP antagonist (GREM1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu23108	NM_001368719.1 Latest version!	Homo sapiens gremlin 1, DAN family BMP antagonist (GREM1), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu11337	NM_001191322.2 Latest version!	Homo sapiens gremlin 1, DAN family BMP antagonist (GREM1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu11815	NM_001191323.2 Latest version!	Homo sapiens gremlin 1, DAN family BMP antagonist (GREM1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu85350	XM_017022077.1 Latest version!	Homo sapiens gremlin 1, DAN family BMP antagonist (GREM1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu48229	XM_005254301.2 Latest version!	Homo sapiens gremlin 1, DAN family BMP antagonist (GREM1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00
View Old Accession Versions >>
OHu11815	NM_001191323.1	Homo sapiens gremlin 1, DAN family BMP antagonist (GREM1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu23108	NM_013372.6	Homo sapiens gremlin 1, DAN family BMP antagonist (GREM1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu11337	NM_001191322.1	Homo sapiens gremlin 1, DAN family BMP antagonist (GREM1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

GREM1 ( NM_013372.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_037504.1 Homo sapiens gremlin 1, DAN family BMP antagonist (GREM1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu23108
Clone ID Related Accession (Same CDS sequence)	NM_013372.6 , NM_001368719.1 , NM_013372.7
Accession Version	NM_013372.6	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 555bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-31
Organism	Homo sapiens(human)
Product	gremlin-1 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK095890.1, AC090877.4 and W19275.1. This sequence is a reference standard in the RefSeqGene project. On Jul 17, 2010 this sequence version replaced NM_013372.5. Transcript Variant: This variant (1) is the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DA573392.1, AY232290.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGCCGCA CAGCCTACAC GGTGGGAGCC CTGCTTCTCC TCTTGGGGAC CCTGCTGCCG 
GCTGCTGAAG GGAAAAAGAA AGGGTCCCAA GGTGCCATCC CCCCGCCAGA CAAGGCCCAG 
CACAATGACT CAGAGCAGAC TCAGTCGCCC CAGCAGCCTG GCTCCAGGAA CCGGGGGCGG 
GGCCAAGGGC GGGGCACTGC CATGCCCGGG GAGGAGGTGC TGGAGTCCAG CCAAGAGGCC 
CTGCATGTGA CGGAGCGCAA ATACCTGAAG CGAGACTGGT GCAAAACCCA GCCGCTTAAG 
CAGACCATCC ACGAGGAAGG CTGCAACAGT CGCACCATCA TCAACCGCTT CTGTTACGGC 
CAGTGCAACT CTTTCTACAT CCCCAGGCAC ATCCGGAAGG AGGAAGGTTC CTTTCAGTCC 
TGCTCCTTCT GCAAGCCCAA GAAATTCACT ACCATGATGG TCACACTCAA CTGCCCTGAA 
CTACAGCCAC CTACCAAGAA GAAGAGAGTC ACACGTGTGA AGCAGTGTCG TTGCATATCC 
ATCGATTTGG ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_037504.1
CDS	160..714
Translation	MSRTAYTVGALLLLLGTLLPAAEGKKKGSQGAIPPPDKAQHNDSEQTQSPQQPGSRNRGRGQGRGTAMPGEEVLESSQEALHVTERKYLKRDWCKTQPLKQTIHEEGCNSRTIINRFCYGQCNSFYIPRHIRKEEGSFQSCSFCKPKKFTTMMVTLNCPELQPPTKKKRVTRVKQCRCISIDLD

Target ORF information:

RefSeq Version	NM_013372.6
Organism	Homo sapiens(human)
Definition	Homo sapiens gremlin 1, DAN family BMP antagonist (GREM1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013372.6

ORF Insert Sequence:

ATGAGCCGCA CAGCCTACAC GGTGGGAGCC CTGCTTCTCC TCTTGGGGAC CCTGCTGCCG 
GCTGCTGAAG GGAAAAAGAA AGGGTCCCAA GGTGCCATCC CCCCGCCAGA CAAGGCCCAG 
CACAATGACT CAGAGCAGAC TCAGTCGCCC CAGCAGCCTG GCTCCAGGAA CCGGGGGCGG 
GGCCAAGGGC GGGGCACTGC CATGCCCGGG GAGGAGGTGC TGGAGTCCAG CCAAGAGGCC 
CTGCATGTGA CGGAGCGCAA ATACCTGAAG CGAGACTGGT GCAAAACCCA GCCGCTTAAG 
CAGACCATCC ACGAGGAAGG CTGCAACAGT CGCACCATCA TCAACCGCTT CTGTTACGGC 
CAGTGCAACT CTTTCTACAT CCCCAGGCAC ATCCGGAAGG AGGAAGGTTC CTTTCAGTCC 
TGCTCCTTCT GCAAGCCCAA GAAATTCACT ACCATGATGG TCACACTCAA CTGCCCTGAA 
CTACAGCCAC CTACCAAGAA GAAGAGAGTC ACACGTGTGA AGCAGTGTCG TTGCATATCC 
ATCGATTTGG ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GREM1 ( NM_001368719.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001355648.1 Homo sapiens gremlin 1, DAN family BMP antagonist (GREM1), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu23108
Clone ID Related Accession (Same CDS sequence)	NM_013372.6 , NM_001368719.1 , NM_013372.7
Accession Version	NM_001368719.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 555bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	gremlin-1 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC090877.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.236918.1, SRR1803613.264747.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: downstream AUG is associated with N-terminal localization signal ##RefSeq-Attributes-END##

ATGAGCCGCA CAGCCTACAC GGTGGGAGCC CTGCTTCTCC TCTTGGGGAC CCTGCTGCCG 
GCTGCTGAAG GGAAAAAGAA AGGGTCCCAA GGTGCCATCC CCCCGCCAGA CAAGGCCCAG 
CACAATGACT CAGAGCAGAC TCAGTCGCCC CAGCAGCCTG GCTCCAGGAA CCGGGGGCGG 
GGCCAAGGGC GGGGCACTGC CATGCCCGGG GAGGAGGTGC TGGAGTCCAG CCAAGAGGCC 
CTGCATGTGA CGGAGCGCAA ATACCTGAAG CGAGACTGGT GCAAAACCCA GCCGCTTAAG 
CAGACCATCC ACGAGGAAGG CTGCAACAGT CGCACCATCA TCAACCGCTT CTGTTACGGC 
CAGTGCAACT CTTTCTACAT CCCCAGGCAC ATCCGGAAGG AGGAAGGTTC CTTTCAGTCC 
TGCTCCTTCT GCAAGCCCAA GAAATTCACT ACCATGATGG TCACACTCAA CTGCCCTGAA 
CTACAGCCAC CTACCAAGAA GAAGAGAGTC ACACGTGTGA AGCAGTGTCG TTGCATATCC 
ATCGATTTGG ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001355648.1
CDS	221..775
Translation	MSRTAYTVGALLLLLGTLLPAAEGKKKGSQGAIPPPDKAQHNDSEQTQSPQQPGSRNRGRGQGRGTAMPGEEVLESSQEALHVTERKYLKRDWCKTQPLKQTIHEEGCNSRTIINRFCYGQCNSFYIPRHIRKEEGSFQSCSFCKPKKFTTMMVTLNCPELQPPTKKKRVTRVKQCRCISIDLD

Target ORF information:

RefSeq Version	NM_001368719.1
Organism	Homo sapiens(human)
Definition	Homo sapiens gremlin 1, DAN family BMP antagonist (GREM1), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001368719.1

ORF Insert Sequence:

ATGAGCCGCA CAGCCTACAC GGTGGGAGCC CTGCTTCTCC TCTTGGGGAC CCTGCTGCCG 
GCTGCTGAAG GGAAAAAGAA AGGGTCCCAA GGTGCCATCC CCCCGCCAGA CAAGGCCCAG 
CACAATGACT CAGAGCAGAC TCAGTCGCCC CAGCAGCCTG GCTCCAGGAA CCGGGGGCGG 
GGCCAAGGGC GGGGCACTGC CATGCCCGGG GAGGAGGTGC TGGAGTCCAG CCAAGAGGCC 
CTGCATGTGA CGGAGCGCAA ATACCTGAAG CGAGACTGGT GCAAAACCCA GCCGCTTAAG 
CAGACCATCC ACGAGGAAGG CTGCAACAGT CGCACCATCA TCAACCGCTT CTGTTACGGC 
CAGTGCAACT CTTTCTACAT CCCCAGGCAC ATCCGGAAGG AGGAAGGTTC CTTTCAGTCC 
TGCTCCTTCT GCAAGCCCAA GAAATTCACT ACCATGATGG TCACACTCAA CTGCCCTGAA 
CTACAGCCAC CTACCAAGAA GAAGAGAGTC ACACGTGTGA AGCAGTGTCG TTGCATATCC 
ATCGATTTGG ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GREM1 ( NM_013372.7 ) cDNA ORF clone, Homo sapiens(human) -> NP_037504.1 Homo sapiens gremlin 1, DAN family BMP antagonist (GREM1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu23108
Clone ID Related Accession (Same CDS sequence)	NM_013372.6 , NM_001368719.1 , NM_013372.7
Accession Version	NM_013372.7 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 555bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	gremlin-1 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK095890.1, AC090877.4 and W19275.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_013372.6. Transcript Variant: This variant (1) is the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.144525.1, SRR1660803.112155.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000651154.1/ ENSP00000498748.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAGCCGCA CAGCCTACAC GGTGGGAGCC CTGCTTCTCC TCTTGGGGAC CCTGCTGCCG 
GCTGCTGAAG GGAAAAAGAA AGGGTCCCAA GGTGCCATCC CCCCGCCAGA CAAGGCCCAG 
CACAATGACT CAGAGCAGAC TCAGTCGCCC CAGCAGCCTG GCTCCAGGAA CCGGGGGCGG 
GGCCAAGGGC GGGGCACTGC CATGCCCGGG GAGGAGGTGC TGGAGTCCAG CCAAGAGGCC 
CTGCATGTGA CGGAGCGCAA ATACCTGAAG CGAGACTGGT GCAAAACCCA GCCGCTTAAG 
CAGACCATCC ACGAGGAAGG CTGCAACAGT CGCACCATCA TCAACCGCTT CTGTTACGGC 
CAGTGCAACT CTTTCTACAT CCCCAGGCAC ATCCGGAAGG AGGAAGGTTC CTTTCAGTCC 
TGCTCCTTCT GCAAGCCCAA GAAATTCACT ACCATGATGG TCACACTCAA CTGCCCTGAA 
CTACAGCCAC CTACCAAGAA GAAGAGAGTC ACACGTGTGA AGCAGTGTCG TTGCATATCC 
ATCGATTTGG ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_037504.1
CDS	160..714
Translation	MSRTAYTVGALLLLLGTLLPAAEGKKKGSQGAIPPPDKAQHNDSEQTQSPQQPGSRNRGRGQGRGTAMPGEEVLESSQEALHVTERKYLKRDWCKTQPLKQTIHEEGCNSRTIINRFCYGQCNSFYIPRHIRKEEGSFQSCSFCKPKKFTTMMVTLNCPELQPPTKKKRVTRVKQCRCISIDLD

Target ORF information:

RefSeq Version	NM_013372.7
Organism	Homo sapiens(human)
Definition	Homo sapiens gremlin 1, DAN family BMP antagonist (GREM1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013372.7

ORF Insert Sequence:

ATGAGCCGCA CAGCCTACAC GGTGGGAGCC CTGCTTCTCC TCTTGGGGAC CCTGCTGCCG 
GCTGCTGAAG GGAAAAAGAA AGGGTCCCAA GGTGCCATCC CCCCGCCAGA CAAGGCCCAG 
CACAATGACT CAGAGCAGAC TCAGTCGCCC CAGCAGCCTG GCTCCAGGAA CCGGGGGCGG 
GGCCAAGGGC GGGGCACTGC CATGCCCGGG GAGGAGGTGC TGGAGTCCAG CCAAGAGGCC 
CTGCATGTGA CGGAGCGCAA ATACCTGAAG CGAGACTGGT GCAAAACCCA GCCGCTTAAG 
CAGACCATCC ACGAGGAAGG CTGCAACAGT CGCACCATCA TCAACCGCTT CTGTTACGGC 
CAGTGCAACT CTTTCTACAT CCCCAGGCAC ATCCGGAAGG AGGAAGGTTC CTTTCAGTCC 
TGCTCCTTCT GCAAGCCCAA GAAATTCACT ACCATGATGG TCACACTCAA CTGCCCTGAA 
CTACAGCCAC CTACCAAGAA GAAGAGAGTC ACACGTGTGA AGCAGTGTCG TTGCATATCC 
ATCGATTTGG ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GREM1 ( NM_001191322.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001178251.1 Homo sapiens gremlin 1, DAN family BMP antagonist (GREM1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu11337
Clone ID Related Accession (Same CDS sequence)	NM_001191322.1 , NM_001191322.2
Accession Version	NM_001191322.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 345bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	gremlin-1 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK095972.1 and AC090877.4. Transcript Variant: This variant (3) lacks an in-frame segment in the CDS, as compared to variant 1. The resulting isoform (3) lacks an internal segment, as compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK095972.1, DA580547.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGAGCCGCA CAGCCTACAC GGTGGGAGCC CTGCATGTGA CGGAGCGCAA ATACCTGAAG 
CGAGACTGGT GCAAAACCCA GCCGCTTAAG CAGACCATCC ACGAGGAAGG CTGCAACAGT 
CGCACCATCA TCAACCGCTT CTGTTACGGC CAGTGCAACT CTTTCTACAT CCCCAGGCAC 
ATCCGGAAGG AGGAAGGTTC CTTTCAGTCC TGCTCCTTCT GCAAGCCCAA GAAATTCACT 
ACCATGATGG TCACACTCAA CTGCCCTGAA CTACAGCCAC CTACCAAGAA GAAGAGAGTC 
ACACGTGTGA AGCAGTGTCG TTGCATATCC ATCGATTTGG ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001178251.1
CDS	160..504
Translation	MSRTAYTVGALHVTERKYLKRDWCKTQPLKQTIHEEGCNSRTIINRFCYGQCNSFYIPRHIRKEEGSFQSCSFCKPKKFTTMMVTLNCPELQPPTKKKRVTRVKQCRCISIDLD

Target ORF information:

RefSeq Version	NM_001191322.1
Organism	Homo sapiens(human)
Definition	Homo sapiens gremlin 1, DAN family BMP antagonist (GREM1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001191322.1

ORF Insert Sequence:

ATGAGCCGCA CAGCCTACAC GGTGGGAGCC CTGCATGTGA CGGAGCGCAA ATACCTGAAG 
CGAGACTGGT GCAAAACCCA GCCGCTTAAG CAGACCATCC ACGAGGAAGG CTGCAACAGT 
CGCACCATCA TCAACCGCTT CTGTTACGGC CAGTGCAACT CTTTCTACAT CCCCAGGCAC 
ATCCGGAAGG AGGAAGGTTC CTTTCAGTCC TGCTCCTTCT GCAAGCCCAA GAAATTCACT 
ACCATGATGG TCACACTCAA CTGCCCTGAA CTACAGCCAC CTACCAAGAA GAAGAGAGTC 
ACACGTGTGA AGCAGTGTCG TTGCATATCC ATCGATTTGG ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GREM1 ( NM_001191322.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001178251.1 Homo sapiens gremlin 1, DAN family BMP antagonist (GREM1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu11337
Clone ID Related Accession (Same CDS sequence)	NM_001191322.1 , NM_001191322.2
Accession Version	NM_001191322.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 345bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	gremlin-1 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK095972.1 and AC090877.4. On May 31, 2019 this sequence version replaced NM_001191322.1. Transcript Variant: This variant (3) lacks an in-frame segment in the CDS, as compared to variant 1. The resulting isoform (3) lacks an internal segment, as compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK095972.1, DA580547.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGAGCCGCA CAGCCTACAC GGTGGGAGCC CTGCATGTGA CGGAGCGCAA ATACCTGAAG 
CGAGACTGGT GCAAAACCCA GCCGCTTAAG CAGACCATCC ACGAGGAAGG CTGCAACAGT 
CGCACCATCA TCAACCGCTT CTGTTACGGC CAGTGCAACT CTTTCTACAT CCCCAGGCAC 
ATCCGGAAGG AGGAAGGTTC CTTTCAGTCC TGCTCCTTCT GCAAGCCCAA GAAATTCACT 
ACCATGATGG TCACACTCAA CTGCCCTGAA CTACAGCCAC CTACCAAGAA GAAGAGAGTC 
ACACGTGTGA AGCAGTGTCG TTGCATATCC ATCGATTTGG ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001178251.1
CDS	160..504
Translation	MSRTAYTVGALHVTERKYLKRDWCKTQPLKQTIHEEGCNSRTIINRFCYGQCNSFYIPRHIRKEEGSFQSCSFCKPKKFTTMMVTLNCPELQPPTKKKRVTRVKQCRCISIDLD

Target ORF information:

RefSeq Version	NM_001191322.2
Organism	Homo sapiens(human)
Definition	Homo sapiens gremlin 1, DAN family BMP antagonist (GREM1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001191322.2

ORF Insert Sequence:

ATGAGCCGCA CAGCCTACAC GGTGGGAGCC CTGCATGTGA CGGAGCGCAA ATACCTGAAG 
CGAGACTGGT GCAAAACCCA GCCGCTTAAG CAGACCATCC ACGAGGAAGG CTGCAACAGT 
CGCACCATCA TCAACCGCTT CTGTTACGGC CAGTGCAACT CTTTCTACAT CCCCAGGCAC 
ATCCGGAAGG AGGAAGGTTC CTTTCAGTCC TGCTCCTTCT GCAAGCCCAA GAAATTCACT 
ACCATGATGG TCACACTCAA CTGCCCTGAA CTACAGCCAC CTACCAAGAA GAAGAGAGTC 
ACACGTGTGA AGCAGTGTCG TTGCATATCC ATCGATTTGG ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GREM1 ( NM_001191323.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001178252.1 Homo sapiens gremlin 1, DAN family BMP antagonist (GREM1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu11815
Clone ID Related Accession (Same CDS sequence)	NM_001191323.1 , NM_001191323.2
Accession Version	NM_001191323.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 432bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	gremlin-1 isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK095890.1 and AC090877.4. Transcript Variant: This variant (2) lacks an in-frame segment in the CDS, as compared to variant 1. The resulting isoform (2) lacks an internal segment, as compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK095890.1, DA556356.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGAGCCGCA CAGCCTACAC GGTGGGAGCC CTGCTTCTCC TCTTGGGGAC CCTGCTGCCG 
GCTGCTGAAG GGAAAAAGAA AGGGTCCCAA GGTGCCATCC CCCCGCCAGA CAAGGCCCTG 
CATGTGACGG AGCGCAAATA CCTGAAGCGA GACTGGTGCA AAACCCAGCC GCTTAAGCAG 
ACCATCCACG AGGAAGGCTG CAACAGTCGC ACCATCATCA ACCGCTTCTG TTACGGCCAG 
TGCAACTCTT TCTACATCCC CAGGCACATC CGGAAGGAGG AAGGTTCCTT TCAGTCCTGC 
TCCTTCTGCA AGCCCAAGAA ATTCACTACC ATGATGGTCA CACTCAACTG CCCTGAACTA 
CAGCCACCTA CCAAGAAGAA GAGAGTCACA CGTGTGAAGC AGTGTCGTTG CATATCCATC 
GATTTGGATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001178252.1
CDS	160..591
Translation	MSRTAYTVGALLLLLGTLLPAAEGKKKGSQGAIPPPDKALHVTERKYLKRDWCKTQPLKQTIHEEGCNSRTIINRFCYGQCNSFYIPRHIRKEEGSFQSCSFCKPKKFTTMMVTLNCPELQPPTKKKRVTRVKQCRCISIDLD

Target ORF information:

RefSeq Version	NM_001191323.1
Organism	Homo sapiens(human)
Definition	Homo sapiens gremlin 1, DAN family BMP antagonist (GREM1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001191323.1

ORF Insert Sequence:

ATGAGCCGCA CAGCCTACAC GGTGGGAGCC CTGCTTCTCC TCTTGGGGAC CCTGCTGCCG 
GCTGCTGAAG GGAAAAAGAA AGGGTCCCAA GGTGCCATCC CCCCGCCAGA CAAGGCCCTG 
CATGTGACGG AGCGCAAATA CCTGAAGCGA GACTGGTGCA AAACCCAGCC GCTTAAGCAG 
ACCATCCACG AGGAAGGCTG CAACAGTCGC ACCATCATCA ACCGCTTCTG TTACGGCCAG 
TGCAACTCTT TCTACATCCC CAGGCACATC CGGAAGGAGG AAGGTTCCTT TCAGTCCTGC 
TCCTTCTGCA AGCCCAAGAA ATTCACTACC ATGATGGTCA CACTCAACTG CCCTGAACTA 
CAGCCACCTA CCAAGAAGAA GAGAGTCACA CGTGTGAAGC AGTGTCGTTG CATATCCATC 
GATTTGGATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GREM1 ( NM_001191323.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001178252.1 Homo sapiens gremlin 1, DAN family BMP antagonist (GREM1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu11815
Clone ID Related Accession (Same CDS sequence)	NM_001191323.1 , NM_001191323.2
Accession Version	NM_001191323.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 432bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	gremlin-1 isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK095890.1 and AC090877.4. On Jun 1, 2019 this sequence version replaced NM_001191323.1. Transcript Variant: This variant (2) lacks an in-frame segment in the CDS, as compared to variant 1. The resulting isoform (2) lacks an internal segment, as compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK095890.1, DA556356.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGAGCCGCA CAGCCTACAC GGTGGGAGCC CTGCTTCTCC TCTTGGGGAC CCTGCTGCCG 
GCTGCTGAAG GGAAAAAGAA AGGGTCCCAA GGTGCCATCC CCCCGCCAGA CAAGGCCCTG 
CATGTGACGG AGCGCAAATA CCTGAAGCGA GACTGGTGCA AAACCCAGCC GCTTAAGCAG 
ACCATCCACG AGGAAGGCTG CAACAGTCGC ACCATCATCA ACCGCTTCTG TTACGGCCAG 
TGCAACTCTT TCTACATCCC CAGGCACATC CGGAAGGAGG AAGGTTCCTT TCAGTCCTGC 
TCCTTCTGCA AGCCCAAGAA ATTCACTACC ATGATGGTCA CACTCAACTG CCCTGAACTA 
CAGCCACCTA CCAAGAAGAA GAGAGTCACA CGTGTGAAGC AGTGTCGTTG CATATCCATC 
GATTTGGATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001178252.1
CDS	160..591
Translation	MSRTAYTVGALLLLLGTLLPAAEGKKKGSQGAIPPPDKALHVTERKYLKRDWCKTQPLKQTIHEEGCNSRTIINRFCYGQCNSFYIPRHIRKEEGSFQSCSFCKPKKFTTMMVTLNCPELQPPTKKKRVTRVKQCRCISIDLD

Target ORF information:

RefSeq Version	NM_001191323.2
Organism	Homo sapiens(human)
Definition	Homo sapiens gremlin 1, DAN family BMP antagonist (GREM1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001191323.2

ORF Insert Sequence:

ATGAGCCGCA CAGCCTACAC GGTGGGAGCC CTGCTTCTCC TCTTGGGGAC CCTGCTGCCG 
GCTGCTGAAG GGAAAAAGAA AGGGTCCCAA GGTGCCATCC CCCCGCCAGA CAAGGCCCTG 
CATGTGACGG AGCGCAAATA CCTGAAGCGA GACTGGTGCA AAACCCAGCC GCTTAAGCAG 
ACCATCCACG AGGAAGGCTG CAACAGTCGC ACCATCATCA ACCGCTTCTG TTACGGCCAG 
TGCAACTCTT TCTACATCCC CAGGCACATC CGGAAGGAGG AAGGTTCCTT TCAGTCCTGC 
TCCTTCTGCA AGCCCAAGAA ATTCACTACC ATGATGGTCA CACTCAACTG CCCTGAACTA 
CAGCCACCTA CCAAGAAGAA GAGAGTCACA CGTGTGAAGC AGTGTCGTTG CATATCCATC 
GATTTGGATT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GREM1 ( XM_017022077.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016877566.1 Homo sapiens gremlin 1, DAN family BMP antagonist (GREM1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu85350
Clone ID Related Accession (Same CDS sequence)	XM_017022077.1
Accession Version	XM_017022077.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 666bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-25
Organism	Homo sapiens(human)
Product	gremlin-1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000015.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Homo sapiens Annotation Release 109 Annotation Version :: 109 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGCTTGG GGCGCCGCGC TGGGTCTGGG GGCGTCTTGG GGCGCCCATT GGAGTCCGCG 
GGTTGGAGCA TCCGGAGAAT CCATGATGTG TGCATTTGCC GATCCCCGAG TATGAGCCGC 
ACAGCCTACA CGGTGGGAGC CCTGCTTCTC CTCTTGGGGA CCCTGCTGCC GGCTGCTGAA 
GGGAAAAAGA AAGGGTCCCA AGGTGCCATC CCCCCGCCAG ACAAGGCCCA GCACAATGAC 
TCAGAGCAGA CTCAGTCGCC CCAGCAGCCT GGCTCCAGGA ACCGGGGGCG GGGCCAAGGG 
CGGGGCACTG CCATGCCCGG GGAGGAGGTG CTGGAGTCCA GCCAAGAGGC CCTGCATGTG 
ACGGAGCGCA AATACCTGAA GCGAGACTGG TGCAAAACCC AGCCGCTTAA GCAGACCATC 
CACGAGGAAG GCTGCAACAG TCGCACCATC ATCAACCGCT TCTGTTACGG CCAGTGCAAC 
TCTTTCTACA TCCCCAGGCA CATCCGGAAG GAGGAAGGTT CCTTTCAGTC CTGCTCCTTC 
TGCAAGCCCA AGAAATTCAC TACCATGATG GTCACACTCA ACTGCCCTGA ACTACAGCCA 
CCTACCAAGA AGAAGAGAGT CACACGTGTG AAGCAGTGTC GTTGCATATC CATCGATTTG 
GATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016877566.1
CDS	95..760
Translation	MCLGRRAGSGGVLGRPLESAGWSIRRIHDVCICRSPSMSRTAYTVGALLLLLGTLLPAAEGKKKGSQGAIPPPDKAQHNDSEQTQSPQQPGSRNRGRGQGRGTAMPGEEVLESSQEALHVTERKYLKRDWCKTQPLKQTIHEEGCNSRTIINRFCYGQCNSFYIPRHIRKEEGSFQSCSFCKPKKFTTMMVTLNCPELQPPTKKKRVTRVKQCRCISIDLD

Target ORF information:

RefSeq Version	XM_017022077.1
Organism	Homo sapiens(human)
Definition	Homo sapiens gremlin 1, DAN family BMP antagonist (GREM1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017022077.1

ORF Insert Sequence:

ATGTGCTTGG GGCGCCGCGC TGGGTCTGGG GGCGTCTTGG GGCGCCCATT GGAGTCCGCG 
GGTTGGAGCA TCCGGAGAAT CCATGATGTG TGCATTTGCC GATCCCCGAG TATGAGCCGC 
ACAGCCTACA CGGTGGGAGC CCTGCTTCTC CTCTTGGGGA CCCTGCTGCC GGCTGCTGAA 
GGGAAAAAGA AAGGGTCCCA AGGTGCCATC CCCCCGCCAG ACAAGGCCCA GCACAATGAC 
TCAGAGCAGA CTCAGTCGCC CCAGCAGCCT GGCTCCAGGA ACCGGGGGCG GGGCCAAGGG 
CGGGGCACTG CCATGCCCGG GGAGGAGGTG CTGGAGTCCA GCCAAGAGGC CCTGCATGTG 
ACGGAGCGCA AATACCTGAA GCGAGACTGG TGCAAAACCC AGCCGCTTAA GCAGACCATC 
CACGAGGAAG GCTGCAACAG TCGCACCATC ATCAACCGCT TCTGTTACGG CCAGTGCAAC 
TCTTTCTACA TCCCCAGGCA CATCCGGAAG GAGGAAGGTT CCTTTCAGTC CTGCTCCTTC 
TGCAAGCCCA AGAAATTCAC TACCATGATG GTCACACTCA ACTGCCCTGA ACTACAGCCA 
CCTACCAAGA AGAAGAGAGT CACACGTGTG AAGCAGTGTC GTTGCATATC CATCGATTTG 
GATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GREM1 ( XM_005254301.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005254358.1 Homo sapiens gremlin 1, DAN family BMP antagonist (GREM1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu48229
Clone ID Related Accession (Same CDS sequence)	XM_005254301.2
Accession Version	XM_005254301.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 723bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	gremlin-1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000015.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005254301.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTGGCA CTCGGTGCGC CTTCCGCGGA CCGGGCGACC CAGTGCACGG CCGCCGCGTC 
ACTCTCGGTC CCGCTGACCC CGCGCCGAGC CCCGGCGGCT CTGGCCGCGG CCGCACTCAG 
CGCCACGCGT CGAAAGCGCA GGCCCCGAGG ACCCGCCGCA CTGACAGTAT GAGCCGCACA 
GCCTACACGG TGGGAGCCCT GCTTCTCCTC TTGGGGACCC TGCTGCCGGC TGCTGAAGGG 
AAAAAGAAAG GGTCCCAAGG TGCCATCCCC CCGCCAGACA AGGCCCAGCA CAATGACTCA 
GAGCAGACTC AGTCGCCCCA GCAGCCTGGC TCCAGGAACC GGGGGCGGGG CCAAGGGCGG 
GGCACTGCCA TGCCCGGGGA GGAGGTGCTG GAGTCCAGCC AAGAGGCCCT GCATGTGACG 
GAGCGCAAAT ACCTGAAGCG AGACTGGTGC AAAACCCAGC CGCTTAAGCA GACCATCCAC 
GAGGAAGGCT GCAACAGTCG CACCATCATC AACCGCTTCT GTTACGGCCA GTGCAACTCT 
TTCTACATCC CCAGGCACAT CCGGAAGGAG GAAGGTTCCT TTCAGTCCTG CTCCTTCTGC 
AAGCCCAAGA AATTCACTAC CATGATGGTC ACACTCAACT GCCCTGAACT ACAGCCACCT 
ACCAAGAAGA AGAGAGTCAC ACGTGTGAAG CAGTGTCGTT GCATATCCAT CGATTTGGAT 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005254358.1
CDS	56..778
Translation	MPGTRCAFRGPGDPVHGRRVTLGPADPAPSPGGSGRGRTQRHASKAQAPRTRRTDSMSRTAYTVGALLLLLGTLLPAAEGKKKGSQGAIPPPDKAQHNDSEQTQSPQQPGSRNRGRGQGRGTAMPGEEVLESSQEALHVTERKYLKRDWCKTQPLKQTIHEEGCNSRTIINRFCYGQCNSFYIPRHIRKEEGSFQSCSFCKPKKFTTMMVTLNCPELQPPTKKKRVTRVKQCRCISIDLD

Target ORF information:

RefSeq Version	XM_005254301.2
Organism	Homo sapiens(human)
Definition	Homo sapiens gremlin 1, DAN family BMP antagonist (GREM1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005254301.2

ORF Insert Sequence:

ATGCCTGGCA CTCGGTGCGC CTTCCGCGGA CCGGGCGACC CAGTGCACGG CCGCCGCGTC 
ACTCTCGGTC CCGCTGACCC CGCGCCGAGC CCCGGCGGCT CTGGCCGCGG CCGCACTCAG 
CGCCACGCGT CGAAAGCGCA GGCCCCGAGG ACCCGCCGCA CTGACAGTAT GAGCCGCACA 
GCCTACACGG TGGGAGCCCT GCTTCTCCTC TTGGGGACCC TGCTGCCGGC TGCTGAAGGG 
AAAAAGAAAG GGTCCCAAGG TGCCATCCCC CCGCCAGACA AGGCCCAGCA CAATGACTCA 
GAGCAGACTC AGTCGCCCCA GCAGCCTGGC TCCAGGAACC GGGGGCGGGG CCAAGGGCGG 
GGCACTGCCA TGCCCGGGGA GGAGGTGCTG GAGTCCAGCC AAGAGGCCCT GCATGTGACG 
GAGCGCAAAT ACCTGAAGCG AGACTGGTGC AAAACCCAGC CGCTTAAGCA GACCATCCAC 
GAGGAAGGCT GCAACAGTCG CACCATCATC AACCGCTTCT GTTACGGCCA GTGCAACTCT 
TTCTACATCC CCAGGCACAT CCGGAAGGAG GAAGGTTCCT TTCAGTCCTG CTCCTTCTGC 
AAGCCCAAGA AATTCACTAC CATGATGGTC ACACTCAACT GCCCTGAACT ACAGCCACCT 
ACCAAGAAGA AGAGAGTCAC ACGTGTGAAG CAGTGTCGTT GCATATCCAT CGATTTGGAT 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gene Symbol	GREM1
Entrez Gene ID	26585
Full Name	gremlin 1, DAN family BMP antagonist
Synonyms	C15DUPq,CKTSF1B1,CRAC1,CRCS4,DAND2,DRM,DUP15q,GREMLIN,HMPS,HMPS1,IHG-2,MPSH,PIG2
General protein information	Preferred Names gremlin 1, DAN family BMP antagonist Names gremlin-1 DAN domain family member 2 cell proliferation-inducing gene 2 protein colorectal adenoma and carcinoma 1 cysteine knot superfamily 1, BMP antagonist 1 down-regulated in Mos-transformed cells protein gremlin 1, cysteine knot superfamily, homolog gremlin 1-like protein increased in high glucose-2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 15 Map Location: 15q13.3
Summary	This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010].
Disorder MIM:	603054

Gallus gallus (chicken)	GREM1	NP_990309.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007994	XP_555475.3
Pan troglodytes (chimpanzee)	GREM1	XP_523036.2
	GREM1	NP_001028020.1
Homo sapiens (human)	GREM1	NP_037504.1
Danio rerio (zebrafish)	LOC100005728	XP_005173629.1
Xenopus tropicalis (tropical clawed frog)	grem1	NP_001093701.1
Canis lupus familiaris (dog)	GREM1	XP_005638258.1
Bos taurus (cattle)	GREM1	NP_001075919.1
Mus musculus (house mouse)	Grem1	NP_035954.1
Rattus norvegicus (Norway rat)	Grem1	NP_062155.1

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

GREM1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Target ORF information:

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ORF Insert Sequence:

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Target ORF information:

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Target ORF information:

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Target ORF information:

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