RGS17 cDNA ORF clone, Homo sapiens(Human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RGS17
Entrez Gene ID	26575
Full Name	regulator of G protein signaling 17
Synonyms	RGS-17,RGSZ2,hRGS17
General protein information	Preferred Names regulator of G protein signaling 17 Names regulator of G-protein signaling 17
Gene Type	protein-coding
Organism	Homo sapiens(Human)
Genome	Chromosome: 6 Map Location: 6q25.2
Summary	This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq, Jul 2008].
Disorder MIM:	607191

mRNA and Protein(s)

mRNA	Protein	Name
XM_017010733.1	XP_016866222.1	regulator of G-protein signaling 17 isoform X1
NM_012419.5	NP_036551.3	regulator of G-protein signaling 17
NM_012419.4	NP_036551.3	regulator of G-protein signaling 17
XM_011535754.1	XP_011534056.1	regulator of G-protein signaling 17 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	RGS17	NP_036551.3
Pan troglodytes (chimpanzee)	RGS17	XP_001141408.1
Canis lupus familiaris (dog)	RGS17	XP_005615583.1
Bos taurus (cattle)	RGS17	NP_001095306.1
Danio rerio (zebrafish)	rgs17	NP_001002523.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007127	XP_308634.3
Xenopus tropicalis (tropical clawed frog)	rgs17	XP_004914725.1
Mus musculus (house mouse)	Rgs17	NP_064342.1
Rattus norvegicus (Norway rat)	Rgs17	NP_001100929.1
Gallus gallus (chicken)	RGS17	NP_990172.1
Drosophila melanogaster (fruit fly)	CG5036	NP_611271.3

Gene Ontology
Bibliography

Related articles in PubMed

Screen Targeting Lung and Prostate Cancer Oncogene Identifies Novel Inhibitors of RGS17 and Problematic Chemical Substructures.
Bodle CR, Schamp JH, O'Brien JB, Hayes MP, Wu M, Doorn JA, Roman DL
SLAS discovery : advancing life sciences R & D2472555217752301(2018 Jan)

miR-203 inhibits cell proliferation, invasion, and migration of non-small-cell lung cancer by downregulating RGS17.
Chi Y, Jin Q, Liu X, Xu L, He X, Shen Y, Zhou Q, Zhang J, Jin M
Cancer science108(12)2366-2372(2017 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Taken together, the results suggested that expression of miR-203 inhibited non-small-cell lung cancer tumor growth and metastasis by targeting RGS17
Title: miR-203 inhibits cell proliferation, invasion, and migration of non-small-cell lung cancer by downregulating RGS17.

Two single nucleotide polymorphisms in the regulator of G-protein signaling 17 gene are associated with smoking initiation.
Title: Large-scale genome-wide association study of Asian population reveals genetic factors in FRMD4A and other loci influencing smoking initiation and nicotine dependence.

Variation in RGS17 was associated with risk for substance dependence diagnoses in both African American and European American populations.
Title: Variation in regulator of G-protein signaling 17 gene (RGS17) is associated with multiple substance dependence diagnoses.

RGS17 is differentially expressed in hepatocellular carcinoma cells and plays a central role in regulating transformed hepatocyte tumorgenicity.
Title: Altered expression and function of regulator of G-protein signaling-17 (RGS17) in hepatocellular carcinoma.

Results establish RGS10 and RGS17 as novel regulators of cell survival and chemoresistance in ovarian cancer cells and suggest that their reduced expression may be diagnostic of chemoresistance.
Title: Regulators of G-Protein signaling RGS10 and RGS17 regulate chemoresistance in ovarian cancer cells.

The following RGS17 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RGS17 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu06221	NM_012419.5 Latest version!	Homo sapiens regulator of G protein signaling 17 (RGS17), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu06221	XM_011535754.1 Latest version!	Homo sapiens regulator of G-protein signaling 17 (RGS17), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu96533	XM_017010733.1 Latest version!	Homo sapiens regulator of G protein signaling 17 (RGS17), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OHu06221	NM_012419.4	Homo sapiens regulator of G protein signaling 17 (RGS17), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RGS17 ( NM_012419.5 ) cDNA ORF clone, Homo sapiens(Human) -> NP_036551.3 Homo sapiens regulator of G protein signaling 17 (RGS17), mRNA.

Price & Availability↑

CloneID	OHu06221
Clone ID Related Accession (Same CDS sequence)	NM_012419.5 , NM_012419.4 , XM_011535754.1
Accession Version	NM_012419.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 633bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	regulator of G-protein signaling 17
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL356963.17, AF202257.3, BC013117.1, AA902430.1, CK902282.1 and AL080276.9. On Nov 23, 2018 this sequence version replaced NM_012419.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC013117.1, SRR3476690.1148404.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1968540 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000206262.2/ ENSP00000206262.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCGAAAAA GGCAGCAGTC CCAAAATGAA GGAACACCTG CCGTGTCTCA AGCTCCTGGA 
AACCAGAGGC CCAACAACAC CTGTTGCTTT TGTTGGTGCT GTTGTTGCAG CTGCTCCTGC 
CTCACTGTGA GGAATGAAGA AAGAGGGGAA AATGCGGGAA GACCCACACA CACTACAAAA 
ATGGAGAGTA TCCAGGTCCT AGAGGAATGC CAAAACCCCA CTGCAGAGGA AGTCTTGTCC 
TGGTCTCAAA ATTTTGACAA GATGATGAAG GCCCCAGCAG GAAGAAACCT TTTCAGAGAG 
TTCCTCCGAA CAGAATACAG TGAAGAGAAC CTACTTTTCT GGCTTGCTTG TGAAGACTTA 
AAGAAGGAGC AGAACAAAAA AGTAATTGAA GAAAAGGCTA GGATGATATA TGAAGATTAC 
ATTTCTATAC TATCACCAAA AGAGGTCAGT CTTGATTCTC GAGTTAGAGA GGTGATCAAT 
AGAAATCTGT TGGATCCCAA TCCTCACATG TATGAAGATG CCCAACTTCA GATATATACT 
TTAATGCACA GAGATTCTTT TCCAAGGTTT TTGAACTCTC AAATTTATAA GTCATTTGTT 
GAAAGTACTG CTGGCTCTTC TTCTGAATCT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036551.3
CDS	185..817
Translation	MRKRQQSQNEGTPAVSQAPGNQRPNNTCCFCWCCCCSCSCLTVRNEERGENAGRPTHTTKMESIQVLEECQNPTAEEVLSWSQNFDKMMKAPAGRNLFREFLRTEYSEENLLFWLACEDLKKEQNKKVIEEKARMIYEDYISILSPKEVSLDSRVREVINRNLLDPNPHMYEDAQLQIYTLMHRDSFPRFLNSQIYKSFVESTAGSSSES

Target ORF information:

RefSeq Version	NM_012419.5
Organism	Homo sapiens(human)
Definition	Homo sapiens regulator of G protein signaling 17 (RGS17), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012419.5

ORF Insert Sequence:

ATGCGAAAAA GGCAGCAGTC CCAAAATGAA GGAACACCTG CCGTGTCTCA AGCTCCTGGA 
AACCAGAGGC CCAACAACAC CTGTTGCTTT TGTTGGTGCT GTTGTTGCAG CTGCTCCTGC 
CTCACTGTGA GGAATGAAGA AAGAGGGGAA AATGCGGGAA GACCCACACA CACTACAAAA 
ATGGAGAGTA TCCAGGTCCT AGAGGAATGC CAAAACCCCA CTGCAGAGGA AGTCTTGTCC 
TGGTCTCAAA ATTTTGACAA GATGATGAAG GCCCCAGCAG GAAGAAACCT TTTCAGAGAG 
TTCCTCCGAA CAGAATACAG TGAAGAGAAC CTACTTTTCT GGCTTGCTTG TGAAGACTTA 
AAGAAGGAGC AGAACAAAAA AGTAATTGAA GAAAAGGCTA GGATGATATA TGAAGATTAC 
ATTTCTATAC TATCACCAAA AGAGGTCAGT CTTGATTCTC GAGTTAGAGA GGTGATCAAT 
AGAAATCTGT TGGATCCCAA TCCTCACATG TATGAAGATG CCCAACTTCA GATATATACT 
TTAATGCACA GAGATTCTTT TCCAAGGTTT TTGAACTCTC AAATTTATAA GTCATTTGTT 
GAAAGTACTG CTGGCTCTTC TTCTGAATCT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RGS17 ( NM_012419.4 ) cDNA ORF clone, Homo sapiens(Human) -> NP_036551.3 Homo sapiens regulator of G protein signaling 17 (RGS17), mRNA.

Price & Availability↑

CloneID	OHu06221
Clone ID Related Accession (Same CDS sequence)	NM_012419.5 , NM_012419.4 , XM_011535754.1
Accession Version	NM_012419.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 633bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-17
Organism	Homo sapiens(human)
Product	regulator of G-protein signaling 17
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF202257.3, BC013117.1, AA902430.1 and CK902282.1. On Dec 23, 2004 this sequence version replaced NM_012419.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC013117.1, SRR1660803.370783.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1968540 [ECO:0000350] ##Evidence-Data-END##

ATGCGAAAAA GGCAGCAGTC CCAAAATGAA GGAACACCTG CCGTGTCTCA AGCTCCTGGA 
AACCAGAGGC CCAACAACAC CTGTTGCTTT TGTTGGTGCT GTTGTTGCAG CTGCTCCTGC 
CTCACTGTGA GGAATGAAGA AAGAGGGGAA AATGCGGGAA GACCCACACA CACTACAAAA 
ATGGAGAGTA TCCAGGTCCT AGAGGAATGC CAAAACCCCA CTGCAGAGGA AGTCTTGTCC 
TGGTCTCAAA ATTTTGACAA GATGATGAAG GCCCCAGCAG GAAGAAACCT TTTCAGAGAG 
TTCCTCCGAA CAGAATACAG TGAAGAGAAC CTACTTTTCT GGCTTGCTTG TGAAGACTTA 
AAGAAGGAGC AGAACAAAAA AGTAATTGAA GAAAAGGCTA GGATGATATA TGAAGATTAC 
ATTTCTATAC TATCACCAAA AGAGGTCAGT CTTGATTCTC GAGTTAGAGA GGTGATCAAT 
AGAAATCTGT TGGATCCCAA TCCTCACATG TATGAAGATG CCCAACTTCA GATATATACT 
TTAATGCACA GAGATTCTTT TCCAAGGTTT TTGAACTCTC AAATTTATAA GTCATTTGTT 
GAAAGTACTG CTGGCTCTTC TTCTGAATCT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036551.3
CDS	157..789
Translation	MRKRQQSQNEGTPAVSQAPGNQRPNNTCCFCWCCCCSCSCLTVRNEERGENAGRPTHTTKMESIQVLEECQNPTAEEVLSWSQNFDKMMKAPAGRNLFREFLRTEYSEENLLFWLACEDLKKEQNKKVIEEKARMIYEDYISILSPKEVSLDSRVREVINRNLLDPNPHMYEDAQLQIYTLMHRDSFPRFLNSQIYKSFVESTAGSSSES

Target ORF information:

RefSeq Version	NM_012419.4
Organism	Homo sapiens(human)
Definition	Homo sapiens regulator of G protein signaling 17 (RGS17), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012419.4

ORF Insert Sequence:

ATGCGAAAAA GGCAGCAGTC CCAAAATGAA GGAACACCTG CCGTGTCTCA AGCTCCTGGA 
AACCAGAGGC CCAACAACAC CTGTTGCTTT TGTTGGTGCT GTTGTTGCAG CTGCTCCTGC 
CTCACTGTGA GGAATGAAGA AAGAGGGGAA AATGCGGGAA GACCCACACA CACTACAAAA 
ATGGAGAGTA TCCAGGTCCT AGAGGAATGC CAAAACCCCA CTGCAGAGGA AGTCTTGTCC 
TGGTCTCAAA ATTTTGACAA GATGATGAAG GCCCCAGCAG GAAGAAACCT TTTCAGAGAG 
TTCCTCCGAA CAGAATACAG TGAAGAGAAC CTACTTTTCT GGCTTGCTTG TGAAGACTTA 
AAGAAGGAGC AGAACAAAAA AGTAATTGAA GAAAAGGCTA GGATGATATA TGAAGATTAC 
ATTTCTATAC TATCACCAAA AGAGGTCAGT CTTGATTCTC GAGTTAGAGA GGTGATCAAT 
AGAAATCTGT TGGATCCCAA TCCTCACATG TATGAAGATG CCCAACTTCA GATATATACT 
TTAATGCACA GAGATTCTTT TCCAAGGTTT TTGAACTCTC AAATTTATAA GTCATTTGTT 
GAAAGTACTG CTGGCTCTTC TTCTGAATCT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RGS17 ( XM_011535754.1 ) cDNA ORF clone, Homo sapiens(Human) -> XP_011534056.1 Homo sapiens regulator of G-protein signaling 17 (RGS17), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu06221
Clone ID Related Accession (Same CDS sequence)	NM_012419.5 , NM_012419.4 , XM_011535754.1
Accession Version	XM_011535754.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 633bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	regulator of G-protein signaling 17 isoform X1
Comment

ATGCGAAAAA GGCAGCAGTC CCAAAATGAA GGAACACCTG CCGTGTCTCA AGCTCCTGGA 
AACCAGAGGC CCAACAACAC CTGTTGCTTT TGTTGGTGCT GTTGTTGCAG CTGCTCCTGC 
CTCACTGTGA GGAATGAAGA AAGAGGGGAA AATGCGGGAA GACCCACACA CACTACAAAA 
ATGGAGAGTA TCCAGGTCCT AGAGGAATGC CAAAACCCCA CTGCAGAGGA AGTCTTGTCC 
TGGTCTCAAA ATTTTGACAA GATGATGAAG GCCCCAGCAG GAAGAAACCT TTTCAGAGAG 
TTCCTCCGAA CAGAATACAG TGAAGAGAAC CTACTTTTCT GGCTTGCTTG TGAAGACTTA 
AAGAAGGAGC AGAACAAAAA AGTAATTGAA GAAAAGGCTA GGATGATATA TGAAGATTAC 
ATTTCTATAC TATCACCAAA AGAGGTCAGT CTTGATTCTC GAGTTAGAGA GGTGATCAAT 
AGAAATCTGT TGGATCCCAA TCCTCACATG TATGAAGATG CCCAACTTCA GATATATACT 
TTAATGCACA GAGATTCTTT TCCAAGGTTT TTGAACTCTC AAATTTATAA GTCATTTGTT 
GAAAGTACTG CTGGCTCTTC TTCTGAATCT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011534056.1
Translation	MRKRQQSQNEGTPAVSQAPGNQRPNNTCCFCWCCCCSCSCLTVRNEERGENAGRPTHTTKMESIQVLEECQNPTAEEVLSWSQNFDKMMKAPAGRNLFREFLRTEYSEENLLFWLACEDLKKEQNKKVIEEKARMIYEDYISILSPKEVSLDSRVREVINRNLLDPNPHMYEDAQLQIYTLMHRDSFPRFLNSQIYKSFVESTAGSSSES

Target ORF information:

RefSeq Version	XM_011535754.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens regulator of G-protein signaling 17 (RGS17), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011535754.1

ORF Insert Sequence:

ATGCGAAAAA GGCAGCAGTC CCAAAATGAA GGAACACCTG CCGTGTCTCA AGCTCCTGGA 
AACCAGAGGC CCAACAACAC CTGTTGCTTT TGTTGGTGCT GTTGTTGCAG CTGCTCCTGC 
CTCACTGTGA GGAATGAAGA AAGAGGGGAA AATGCGGGAA GACCCACACA CACTACAAAA 
ATGGAGAGTA TCCAGGTCCT AGAGGAATGC CAAAACCCCA CTGCAGAGGA AGTCTTGTCC 
TGGTCTCAAA ATTTTGACAA GATGATGAAG GCCCCAGCAG GAAGAAACCT TTTCAGAGAG 
TTCCTCCGAA CAGAATACAG TGAAGAGAAC CTACTTTTCT GGCTTGCTTG TGAAGACTTA 
AAGAAGGAGC AGAACAAAAA AGTAATTGAA GAAAAGGCTA GGATGATATA TGAAGATTAC 
ATTTCTATAC TATCACCAAA AGAGGTCAGT CTTGATTCTC GAGTTAGAGA GGTGATCAAT 
AGAAATCTGT TGGATCCCAA TCCTCACATG TATGAAGATG CCCAACTTCA GATATATACT 
TTAATGCACA GAGATTCTTT TCCAAGGTTT TTGAACTCTC AAATTTATAA GTCATTTGTT 
GAAAGTACTG CTGGCTCTTC TTCTGAATCT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RGS17 ( XM_017010733.1 ) cDNA ORF clone, Homo sapiens(Human) -> XP_016866222.1 Homo sapiens regulator of G protein signaling 17 (RGS17), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu96533
Clone ID Related Accession (Same CDS sequence)	XM_017010733.1
Accession Version	XM_017010733.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 480bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	regulator of G-protein signaling 17 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGAAAAA GGCAGCAGTC CCAAAATGAA GGAACACCTG CCGTGTCTCA AGCTCCTGGA 
AACCAGAGGC CCAACAACAC CTGTTGCTTT TGTTGGTGCT GTTGTTGCAG CTGCTCCTGC 
CTCACTGTGA GGAATGAAGA AAGAGGGGAA AATGCGGGAA GACCCACACA CACTACAAAA 
ATGGAGAGTA TCCAGGTCCT AGAGGAATGC CAAAACCCCA CTGCAGAGGA AGTCTTGTCC 
TGGTCTCAAA ATTTTGACAA GATGATGAAG GCCCCAGCAG GAAGAAACCT TTTCAGAGAG 
TTCCTCCGAA CAGAATACAG TGAAGAGAAC CTACTTTTCT GGCTTGCTTG TGAAGACTTA 
AAGAAGGAGC AGAACAAAAA AGTAATTGAA GAAAAGGCTA GGATGATATA TGAAGATTAC 
ATTTCTATAC TATCACCAAA AGAGGTAAAA ATCTGGAAAA CATTGAGGTG GGCTTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016866222.1
CDS	187..666
Translation	MRKRQQSQNEGTPAVSQAPGNQRPNNTCCFCWCCCCSCSCLTVRNEERGENAGRPTHTTKMESIQVLEECQNPTAEEVLSWSQNFDKMMKAPAGRNLFREFLRTEYSEENLLFWLACEDLKKEQNKKVIEEKARMIYEDYISILSPKEVKIWKTLRWAS

Target ORF information:

RefSeq Version	XM_017010733.1
Organism	Homo sapiens(human)
Definition	Homo sapiens regulator of G protein signaling 17 (RGS17), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017010733.1

ORF Insert Sequence:

ATGCGAAAAA GGCAGCAGTC CCAAAATGAA GGAACACCTG CCGTGTCTCA AGCTCCTGGA 
AACCAGAGGC CCAACAACAC CTGTTGCTTT TGTTGGTGCT GTTGTTGCAG CTGCTCCTGC 
CTCACTGTGA GGAATGAAGA AAGAGGGGAA AATGCGGGAA GACCCACACA CACTACAAAA 
ATGGAGAGTA TCCAGGTCCT AGAGGAATGC CAAAACCCCA CTGCAGAGGA AGTCTTGTCC 
TGGTCTCAAA ATTTTGACAA GATGATGAAG GCCCCAGCAG GAAGAAACCT TTTCAGAGAG 
TTCCTCCGAA CAGAATACAG TGAAGAGAAC CTACTTTTCT GGCTTGCTTG TGAAGACTTA 
AAGAAGGAGC AGAACAAAAA AGTAATTGAA GAAAAGGCTA GGATGATATA TGAAGATTAC 
ATTTCTATAC TATCACCAAA AGAGGTAAAA ATCTGGAAAA CATTGAGGTG GGCTTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Screen Targeting Lung and Prostate Cancer Oncogene Identifies Novel Inhibitors of RGS17 and Problematic Chemical Substructures.
SLAS discovery : advancing life sciences R & D2472555217752301(2018 Jan)
Bodle CR,Schamp JH,O'Brien JB,Hayes MP,Wu M,Doorn JA,Roman DL

miR-203 inhibits cell proliferation, invasion, and migration of non-small-cell lung cancer by downregulating RGS17.
Cancer science108(12)2366-2372(2017 Dec)
Chi Y,Jin Q,Liu X,Xu L,He X,Shen Y,Zhou Q,Zhang J,Jin M

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RGS17 cDNA ORF clone, Homo sapiens(Human)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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