Gene Symbol | KAT2A |
Entrez Gene ID | 2648 |
Full Name | lysine acetyltransferase 2A |
Synonyms | GCN5,GCN5L2,PCAF-b,hGCN5 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).[supplied by OMIM, Sep 2009]. |
Disorder MIM: |