TAS2R41 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TAS2R41
Entrez Gene ID	259287
Full Name	taste 2 receptor member 41
Synonyms	T2R41,T2R59
General protein information	Preferred Names taste 2 receptor member 41 Names taste receptor type 2 member 41 taste receptor type 2 member 59 taste receptor, type 2, member 41
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7q35
Summary	This gene encodes a member of the bitter taste receptor family which belong to the G protein-coupled receptor superfamily and are predominantly expressed in taste receptor cells of the tongue and palate epithelia. This intronless taste receptor gene encodes a seven-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered together with eight other taste receptor genes on chromosome 7. Chloramphenicol is an agonist for the encoded protein. [provided by RefSeq, Jul 2017].
Disorder MIM:	613965

mRNA and Protein(s)

mRNA	Protein	Name
NM_176883.2	NP_795364.2	taste receptor type 2 member 41

Pathways from BioSystems

Homologies

Bos taurus (cattle)	TAS2R41	XP_002687168.1
Xenopus tropicalis (tropical clawed frog)	t2r14	NP_001165529.1
Xenopus tropicalis (tropical clawed frog)	t2r11	NP_001165528.1
Homo sapiens (human)	TAS2R41	NP_795364.2
Canis lupus familiaris (dog)	TAS2R41	NP_001074192.1
Mus musculus (house mouse)	Tas2r126	NP_996911.1
Pan troglodytes (chimpanzee)	TAS2R41	NP_001009128.1
Rattus norvegicus (Norway rat)	Tas2r126	NP_647551.1
Xenopus tropicalis (tropical clawed frog)	t2r13	NP_001165474.1
	TAS2R41	XP_001092228.1

Gene Ontology
Bibliography

Related articles in PubMed

Major haplotypes of the human bitter taste receptor TAS2R41 encode functional receptors for chloramphenicol.
Thalmann S, Behrens M, Meyerhof W
Biochemical and biophysical research communications435(2)267-73(2013 May)

The molecular receptive ranges of human TAS2R bitter taste receptors.
Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, Bufe B, Appendino G, Behrens M
Chemical senses35(2)157-70(2010 Feb)

Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.
Go Y, Satta Y, Takenaka O, Takahata N
Genetics170(1)313-26(2005 May)

Evolution of bitter taste receptors in humans and apes.
Fischer A, Gilad Y, Man O, P??bo S
Molecular biology and evolution22(3)432-6(2005 Mar)

Identification and characterization of human taste receptor genes belonging to the TAS2R family.
Conte C, Ebeling M, Marcuz A, Nef P, Andres-Barquin PJ
Cytogenetic and genome research98(1)45-53(2002)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following TAS2R41 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TAS2R41 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu30183	NM_176883.2 Latest version!	Homo sapiens taste 2 receptor member 41 (TAS2R41), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TAS2R41 ( NM_176883.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_795364.2 Homo sapiens taste 2 receptor member 41 (TAS2R41), mRNA.

Price & Availability↑

CloneID	OHu30183
Clone ID Related Accession (Same CDS sequence)	NM_176883.2
Accession Version	NM_176883.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 924bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Homo sapiens(human)
Product	taste receptor type 2 member 41
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY114093.1. On Oct 19, 2006 this sequence version replaced NM_176883.1. ##Evidence-Data-START## Transcript is intronless :: BC101157.3 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000408916.1/ ENSP00000386201.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGCAAGCAG CACTGACGGC CTTCTTCGTG TTGCTCTTTA GCCTGCTGAG TCTTCTGGGG 
ATTGCAGCGA ATGGCTTCAT TGTGCTGGTG CTGGGCAGGG AGTGGCTGCG ATATGGCAGG 
TTGCTGCCCT TGGATATGAT CCTCATTAGC TTGGGTGCCT CCCGCTTCTG CCTGCAGTTG 
GTTGGGACGG TGCACAACTT CTACTACTCT GCCCAGAAGG TCGAGTACTC TGGGGGTCTC 
GGCCGACAGT TCTTCCATCT ACACTGGCAC TTCCTGAACT CAGCCACCTT CTGGTTTTGC 
AGCTGGCTCA GTGTCCTGTT CTGTGTGAAG ATTGCTAACA TCACACACTC CACCTTCCTG 
TGGCTGAAGT GGAGGTTCCC AGGGTGGGTG CCCTGGCTCC TGTTGGGCTC TGTCCTGATC 
TCCTTCATCA TAACCCTGCT GTTTTTTTGG GTGAACTACC CTGTATATCA AGAATTTTTA 
ATTAGAAAAT TTTCTGGGAA CATGACCTAC AAGTGGAATA CAAGGATAGA AACATACTAT 
TTCCCATCCC TGAAACTGGT CATCTGGTCA ATTCCTTTTT CTGTTTTTCT GGTCTCAATT 
ATGCTGTTAA TTAATTCTCT GAGGAGGCAT ACTCAGAGAA TGCAGCACAA CGGGCACAGC 
CTGCAGGACC CCAGCACCCA GGCTCACACC AGAGCTCTGA AGTCCCTCAT CTCCTTCCTC 
ATTCTTTATG CTCTGTCCTT TCTGTCCCTG ATCATTGATG CCGCAAAATT TATCTCCATG 
CAGAACGACT TTTACTGGCC ATGGCAAATT GCAGTCTACC TGTGCATATC TGTCCATCCC 
TTCATCCTCA TCTTCAGCAA CCTCAAGCTT CGAAGCGTGT TCTCGCAGCT CCTGTTGTTG 
GCAAGGGGCT TCTGGGTGGC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_795364.2
CDS	1..924
Translation	MQAALTAFFVLLFSLLSLLGIAANGFIVLVLGREWLRYGRLLPLDMILISLGASRFCLQLVGTVHNFYYSAQKVEYSGGLGRQFFHLHWHFLNSATFWFCSWLSVLFCVKIANITHSTFLWLKWRFPGWVPWLLLGSVLISFIITLLFFWVNYPVYQEFLIRKFSGNMTYKWNTRIETYYFPSLKLVIWSIPFSVFLVSIMLLINSLRRHTQRMQHNGHSLQDPSTQAHTRALKSLISFLILYALSFLSLIIDAAKFISMQNDFYWPWQIAVYLCISVHPFILIFSNLKLRSVFSQLLLLARGFWVA

Target ORF information:

RefSeq Version	NM_176883.2
Organism	Homo sapiens(human)
Definition	Homo sapiens taste 2 receptor member 41 (TAS2R41), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_176883.2

ORF Insert Sequence:

ATGCAAGCAG CACTGACGGC CTTCTTCGTG TTGCTCTTTA GCCTGCTGAG TCTTCTGGGG 
ATTGCAGCGA ATGGCTTCAT TGTGCTGGTG CTGGGCAGGG AGTGGCTGCG ATATGGCAGG 
TTGCTGCCCT TGGATATGAT CCTCATTAGC TTGGGTGCCT CCCGCTTCTG CCTGCAGTTG 
GTTGGGACGG TGCACAACTT CTACTACTCT GCCCAGAAGG TCGAGTACTC TGGGGGTCTC 
GGCCGACAGT TCTTCCATCT ACACTGGCAC TTCCTGAACT CAGCCACCTT CTGGTTTTGC 
AGCTGGCTCA GTGTCCTGTT CTGTGTGAAG ATTGCTAACA TCACACACTC CACCTTCCTG 
TGGCTGAAGT GGAGGTTCCC AGGGTGGGTG CCCTGGCTCC TGTTGGGCTC TGTCCTGATC 
TCCTTCATCA TAACCCTGCT GTTTTTTTGG GTGAACTACC CTGTATATCA AGAATTTTTA 
ATTAGAAAAT TTTCTGGGAA CATGACCTAC AAGTGGAATA CAAGGATAGA AACATACTAT 
TTCCCATCCC TGAAACTGGT CATCTGGTCA ATTCCTTTTT CTGTTTTTCT GGTCTCAATT 
ATGCTGTTAA TTAATTCTCT GAGGAGGCAT ACTCAGAGAA TGCAGCACAA CGGGCACAGC 
CTGCAGGACC CCAGCACCCA GGCTCACACC AGAGCTCTGA AGTCCCTCAT CTCCTTCCTC 
ATTCTTTATG CTCTGTCCTT TCTGTCCCTG ATCATTGATG CCGCAAAATT TATCTCCATG 
CAGAACGACT TTTACTGGCC ATGGCAAATT GCAGTCTACC TGTGCATATC TGTCCATCCC 
TTCATCCTCA TCTTCAGCAA CCTCAAGCTT CGAAGCGTGT TCTCGCAGCT CCTGTTGTTG 
GCAAGGGGCT TCTGGGTGGC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Major haplotypes of the human bitter taste receptor TAS2R41 encode functional receptors for chloramphenicol.
Biochemical and biophysical research communications435(2)267-73(2013 May)
Thalmann S,Behrens M,Meyerhof W

The molecular receptive ranges of human TAS2R bitter taste receptors.
Chemical senses35(2)157-70(2010 Feb)
Meyerhof W,Batram C,Kuhn C,Brockhoff A,Chudoba E,Bufe B,Appendino G,Behrens M

Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.
Genetics170(1)313-26(2005 May)
Go Y,Satta Y,Takenaka O,Takahata N

Evolution of bitter taste receptors in humans and apes.
Molecular biology and evolution22(3)432-6(2005 Mar)
Fischer A,Gilad Y,Man O,P??bo S

Identification and characterization of human taste receptor genes belonging to the TAS2R family.
Cytogenetic and genome research98(1)45-53(2002)
Conte C,Ebeling M,Marcuz A,Nef P,Andres-Barquin PJ

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TAS2R41 cDNA ORF clone, Homo sapiens(human)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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