GAGE5 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	GAGE5
Entrez Gene ID	2577
Full Name	G antigen 5
Synonyms	CT4.5
General protein information	Preferred Names G antigen 5 Names G antigen 5 GAGE-5 cancer/testis antigen 4.5 cancer/testis antigen family 4, member 5
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xp11.4-p11.2
Summary	This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YYWPRPRRY, which is also encoded by several other family members, is recognized by autologous cytolytic T lymphocytes. [provided by RefSeq, Jul 2008].
Disorder MIM:	300598

mRNA and Protein(s)

mRNA	Protein	Name
NM_001475.1	NP_001466.1	G antigen 5

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Next-generation sequencing to generate interactome datasets.
Yu H, Tardivo L, Tam S, Weiner E, Gebreab F, Fan C, Svrzikapa N, Hirozane-Kishikawa T, Rietman E, Yang X, Sahalie J, Salehi-Ashtiani K, Hao T, Cusick ME, Hill DE, Roth FP, Braun P, Vidal M
Nature methods8(6)478-80(2011 Jun)

Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells.
Lee OH, Kim H, He Q, Baek HJ, Yang D, Chen LY, Liang J, Chae HK, Safari A, Liu D, Songyang Z
Molecular & cellular proteomics : MCP10(2)M110.001628(2011 Feb)

An overview of the GAGE cancer/testis antigen family with the inclusion of newly identified members.
Gjerstorff MF, Ditzel HJ
Tissue antigens71(3)187-92(2008 Mar)

Characterization of the GAGE genes that are expressed in various human cancers and in normal testis.
De Backer O, Arden KC, Boretti M, Vantomme V, De Smet C, Czekay S, Viars CS, De Plaen E, Brasseur F, Chomez P, Van den Eynde B, Boon T, van der Bruggen P
Cancer research59(13)3157-65(1999 Jul)

Isolation and characterization of PAGE-1 and GAGE-7. New genes expressed in the LNCaP prostate cancer progression model that share homology with melanoma-associated antigens.
Chen ME, Lin SH, Chung LW, Sikes RA
The Journal of biological chemistry273(28)17618-25(1998 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following GAGE5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GAGE5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu24190	NM_001475.1 Latest version!	Homo sapiens G antigen 5 (GAGE5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GAGE5 ( NM_001475.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001466.1 Homo sapiens G antigen 5 (GAGE5), mRNA.

Price & Availability↑

CloneID	OHu24190
Clone ID Related Accession (Same CDS sequence)	NM_001475.1
Accession Version	NM_001475.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 354bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-03
Organism	Homo sapiens(human)
Product	G antigen 5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from U19146.1. ##Evidence-Data-START## Transcript exon combination :: U19146.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAGTTGGC GAGGAAGATC GACCTATTAT TGGCCTAGAC CAAGGCGCTA TGTACAGCCT 
CCTGAAGTGA TTGGGCCTAT GCGGCCCGAG CAGTTCAGTG ATGAAGTGGA ACCAGCAACA 
CCTGAAGAAG GGGAACCAGC AACTCAACGT CAGGATCCTG CAGCTGCTCA GGAGGGAGAG 
GATGAGGGAG CATCTGCAGG TCAAGGGCCG AAGCCTGAAG CTGATAGCCA GGAACAGGGT 
CACCCACAGA CTGGGTGTGA GTGTGAAGAT GGTCCTGATG GGCAGGAGAT GGACCCGCCA 
AATCCAGAGG AGGTGAAAAC GCCTGAAGAA GGTGAAAAGC AATCACAGTG TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001466.1
CDS	75..428
Translation	MSWRGRSTYYWPRPRRYVQPPEVIGPMRPEQFSDEVEPATPEEGEPATQRQDPAAAQEGEDEGASAGQGPKPEADSQEQGHPQTGCECEDGPDGQEMDPPNPEEVKTPEEGEKQSQC

Target ORF information:

RefSeq Version	NM_001475.1
Organism	Homo sapiens(human)
Definition	Homo sapiens G antigen 5 (GAGE5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001475.1

ORF Insert Sequence:

ATGAGTTGGC GAGGAAGATC GACCTATTAT TGGCCTAGAC CAAGGCGCTA TGTACAGCCT 
CCTGAAGTGA TTGGGCCTAT GCGGCCCGAG CAGTTCAGTG ATGAAGTGGA ACCAGCAACA 
CCTGAAGAAG GGGAACCAGC AACTCAACGT CAGGATCCTG CAGCTGCTCA GGAGGGAGAG 
GATGAGGGAG CATCTGCAGG TCAAGGGCCG AAGCCTGAAG CTGATAGCCA GGAACAGGGT 
CACCCACAGA CTGGGTGTGA GTGTGAAGAT GGTCCTGATG GGCAGGAGAT GGACCCGCCA 
AATCCAGAGG AGGTGAAAAC GCCTGAAGAA GGTGAAAAGC AATCACAGTG TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Next-generation sequencing to generate interactome datasets.
Nature methods8(6)478-80(2011 Jun)
Yu H,Tardivo L,Tam S,Weiner E,Gebreab F,Fan C,Svrzikapa N,Hirozane-Kishikawa T,Rietman E,Yang X,Sahalie J,Salehi-Ashtiani K,Hao T,Cusick ME,Hill DE,Roth FP,Braun P,Vidal M

Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells.
Molecular & cellular proteomics : MCP10(2)M110.001628(2011 Feb)
Lee OH,Kim H,He Q,Baek HJ,Yang D,Chen LY,Liang J,Chae HK,Safari A,Liu D,Songyang Z

An overview of the GAGE cancer/testis antigen family with the inclusion of newly identified members.
Tissue antigens71(3)187-92(2008 Mar)
Gjerstorff MF,Ditzel HJ

Characterization of the GAGE genes that are expressed in various human cancers and in normal testis.
Cancer research59(13)3157-65(1999 Jul)
De Backer O,Arden KC,Boretti M,Vantomme V,De Smet C,Czekay S,Viars CS,De Plaen E,Brasseur F,Chomez P,Van den Eynde B,Boon T,van der Bruggen P

Isolation and characterization of PAGE-1 and GAGE-7. New genes expressed in the LNCaP prostate cancer progression model that share homology with melanoma-associated antigens.
The Journal of biological chemistry273(28)17618-25(1998 Jul)
Chen ME,Lin SH,Chung LW,Sikes RA

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GAGE5 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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