SHC2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SHC2
Entrez Gene ID	25759
Full Name	SHC adaptor protein 2
Synonyms	SCK,SHCB,SLI
General protein information	Preferred Names SHC adaptor protein 2 Names SHC-transforming protein 2 SH2 domain protein C2 SHC (Src homology 2 domain containing) transforming protein 2 SHC-transforming protein B neuronal Shc adaptor homolog protein Sck src homology 2 domain-containing-transforming protein C2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19p13.3
Disorder MIM:	605217

mRNA and Protein(s)

mRNA	Protein	Name
XM_011527895.2	XP_011526197.1	SHC-transforming protein 2 isoform X3
XM_017026567.1	XP_016882056.1	SHC-transforming protein 2 isoform X4
XM_011527893.3	XP_011526195.1	SHC-transforming protein 2 isoform X1
XM_011527894.2	XP_011526196.1	SHC-transforming protein 2 isoform X2
XM_011527896.2	XP_011526198.1	SHC-transforming protein 2 isoform X4
NM_012435.2	NP_036567.2	SHC-transforming protein 2
XM_011527893.2	XP_011526195.1	SHC-transforming protein 2 isoform X1

Pathways from BioSystems

Homologies

	SHC2	XP_002801035.1
Gallus gallus (chicken)	SHC2	XP_001233682.3
Homo sapiens (human)	SHC2	NP_036567.2
Canis lupus familiaris (dog)	LOC611955	XP_005633311.1
Danio rerio (zebrafish)	shc2	NP_001038438.1
Xenopus tropicalis (tropical clawed frog)	shc2	XP_002939812.2
Bos taurus (cattle)	LOC533455	XP_002689206.3
Mus musculus (house mouse)	Shc2	NP_001019710.1
Rattus norvegicus (Norway rat)	Shc2	NP_001101535.1

Gene Ontology
Bibliography

Related articles in PubMed

CD95 promotes metastatic spread via Sck in pancreatic ductal adenocarcinoma.
Teodorczyk M, Kleber S, Wollny D, Sefrin JP, Aykut B, Mateos A, Herhaus P, Sancho-Martinez I, Hill O, Gieffers C, Sykora J, Weichert W, Eisen C, Trumpp A, Sprick MR, Bergmann F, Welsch T, Martin-Villalba A
Cell death and differentiation22(7)1192-202(2015 Jul)

Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome.
Leung KK, Hause RJ Jr, Barkinge JL, Ciaccio MF, Chuu CP, Jones RB
Molecular & cellular proteomics : MCP13(7)1705-23(2014 Jul)

SHC2 gene copy number in multiple system atrophy (MSA).
Ferguson MC, Garland EM, Hedges L, Womack-Nunley B, Hamid R, Phillips JA 3rd, Shibao CA, Raj SR, Biaggioni I, Robertson D
Clinical autonomic research : official journal of the Clinical Autonomic Research Society24(1)25-30(2014 Feb)

Copy number loss of (src homology 2 domain containing)-transforming protein 2 (SHC2) gene: discordant loss in monozygotic twins and frequent loss in patients with multiple system atrophy.
Sasaki H, Emi M, Iijima H, Ito N, Sato H, Yabe I, Kato T, Utsumi J, Matsubara K
Molecular brain424(2011 Jun)

Genomic annotation of 15,809 ESTs identified from pooled early gestation human eyes.
Choy KW, Wang CC, Ogura A, Lau TK, Rogers MS, Ikeo K, Gojobori T, Lam DS, Pang CP
Physiological genomics25(1)9-15(2006 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Sck was identified as a novel molecule indispensable for CD95's activation of the PI3K and MAPK pathways and induction of cell cycle progression in pancreatic ductal adenocarcinoma.
Title: CD95 promotes metastatic spread via Sck in pancreatic ductal adenocarcinoma.

SHC2 gene deletions underlie few, if any, cases of well-characterized multiple system atrophy in the US population.
Title: SHC2 gene copy number in multiple system atrophy (MSA).

Data show that copy number loss of SHC2 strongly indicates a causal link to multiple system atrophy.
Title: Copy number loss of (src homology 2 domain containing)-transforming protein 2 (SHC2) gene: discordant loss in monozygotic twins and frequent loss in patients with multiple system atrophy.

The following SHC2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SHC2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu66461	XM_017026567.1 Latest version!	Homo sapiens SHC adaptor protein 2 (SHC2), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu66461	XM_011527896.2 Latest version!	Homo sapiens SHC adaptor protein 2 (SHC2), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu31440	NM_012435.2 Latest version!	Homo sapiens SHC adaptor protein 2 (SHC2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$314.30 $449.00
OHu66458	XM_011527893.3 Latest version!	Homo sapiens SHC adaptor protein 2 (SHC2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
OHu66459	XM_011527894.2 Latest version!	Homo sapiens SHC adaptor protein 2 (SHC2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
OHu66460	XM_011527895.2 Latest version!	Homo sapiens SHC adaptor protein 2 (SHC2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
View Old Accession Versions >>
OHu66458	XM_011527893.2	Homo sapiens SHC adaptor protein 2 (SHC2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SHC2 ( XM_017026567.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016882056.1 Homo sapiens SHC adaptor protein 2 (SHC2), transcript variant X5, mRNA.

Price & Availability↑

CloneID	OHu66461
Clone ID Related Accession (Same CDS sequence)	XM_017026567.1 , XM_011527896.2
Accession Version	XM_017026567.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1314bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	SHC-transforming protein 2 isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCTGCA TCGAGGTTCT CCGCTCTATG CGCTCCCTGG ACTTTAACAC GCGCACGCAG 
GTGACCAGGG AAGCCATCAA CCGGCTCCAT GAGGCCGTGC CTGGCGTCCG GGGATCCTGG 
AAGAAAAAGG CCCCCAACAA GGCCCTGGCG TCCGTCCTGG GCAAGAGCAA CCTTCGCTTT 
GCCGGCATGA GCATCTCCAT CCACATCTCC ACTGATGGCC TCAGCCTCTC CGTGCCTGCC 
ACGCGCCAGG TCATCGCCAA CCACCACATG CCGTCCATCT CCTTCGCGTC AGGCGGAGAC 
ACGGACATGA CGGATTACGT GGCCTACGTC GCCAAGGACC CCATCAACCA GAGAGCCTGC 
CACATCCTGG AGTGCTGTGA GGGCCTGGCA CAGAGCATCA TCAGCACCGT GGGCCAAGCT 
TTCGAGCTGC GCTTCAAGCA GTACCTGCAC AGCCCGCCCA AGGTGGCGCT GCCCCCAGAA 
AGGCTGGCAG GGCCGGAGGA GTCGGCCTGG GGGGACGAGG AGGACTCTTT GGAGCACAAT 
TACTACAACA GCATCCCGGG GAAGGAGCCG CCGCTGGGCG GGCTAGTGGA CTCCAGGCTG 
GCCCTGACAC AGCCCTGCGC CCTCACGGCC CTCGACCAGG GCCCATCTCC TTCTCTAAGA 
GATGCCTGCA GCCTGCCATG GGACGTGGGG TCCACCGGTA CAGCTCCACC GGGGGACGGC 
TACGTGCAGG CGGACGCCCG GGGCCCCCCG GACCACGAGG AGCACCTGTA TGTCAACACC 
CAGGGTCTGG ACGCCCCCGA GCCGGAGGAC AGCCCCAAAA AGGATCTGTT TGACATGCGA 
CCCTTTGAGG ATGCCCTGAA GTTGCATGAG TGCTCAGTGG CGGCAGGCGT GACAGCAGCC 
CCTCTTCCCT TGGAGGACCA GTGGCCCAGC CCCCCTACCC GCCGGGCCCC TGTGGCCCCC 
ACGGAGGAAC AGCTGCGTCA GGAGCCCTGG TACCACGGCC GGATGAGCCG CCGGGCGGCA 
GAGAGGATGC TTCGAGCTGA CGGGGACTTC CTTGTGCGAG ACAGCGTCAC CAACCCCGGG 
CAGTATGTCC TCACCGGCAT GCACGCCGGG CAGCCCAAGC ACCTGCTGCT CGTGGACCCC 
GAGGGCGTGG TAAGCTGTGC ACAGGTGGGA GGGTCTCGGG GCATCCAGGG GCTTCGCTGG 
GCACAGGTGG GAGGGTCTCA AGGGTCTCGA GGGTCTCGGG GCATGCAGGA GCTTTCCATG 
TTTATGAAGT TTTTCCAGAT TGTTCCAGAT GTTGCCTTTG ACCAGCTACT GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016882056.1
CDS	620..1933
Translation	MGCIEVLRSMRSLDFNTRTQVTREAINRLHEAVPGVRGSWKKKAPNKALASVLGKSNLRFAGMSISIHISTDGLSLSVPATRQVIANHHMPSISFASGGDTDMTDYVAYVAKDPINQRACHILECCEGLAQSIISTVGQAFELRFKQYLHSPPKVALPPERLAGPEESAWGDEEDSLEHNYYNSIPGKEPPLGGLVDSRLALTQPCALTALDQGPSPSLRDACSLPWDVGSTGTAPPGDGYVQADARGPPDHEEHLYVNTQGLDAPEPEDSPKKDLFDMRPFEDALKLHECSVAAGVTAAPLPLEDQWPSPPTRRAPVAPTEEQLRQEPWYHGRMSRRAAERMLRADGDFLVRDSVTNPGQYVLTGMHAGQPKHLLLVDPEGVVSCAQVGGSRGIQGLRWAQVGGSQGSRGSRGMQELSMFMKFFQIVPDVAFDQLL

Target ORF information:

RefSeq Version	XM_017026567.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SHC adaptor protein 2 (SHC2), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017026567.1

ORF Insert Sequence:

ATGGGCTGCA TCGAGGTTCT CCGCTCTATG CGCTCCCTGG ACTTTAACAC GCGCACGCAG 
GTGACCAGGG AAGCCATCAA CCGGCTCCAT GAGGCCGTGC CTGGCGTCCG GGGATCCTGG 
AAGAAAAAGG CCCCCAACAA GGCCCTGGCG TCCGTCCTGG GCAAGAGCAA CCTTCGCTTT 
GCCGGCATGA GCATCTCCAT CCACATCTCC ACTGATGGCC TCAGCCTCTC CGTGCCTGCC 
ACGCGCCAGG TCATCGCCAA CCACCACATG CCGTCCATCT CCTTCGCGTC AGGCGGAGAC 
ACGGACATGA CGGATTACGT GGCCTACGTC GCCAAGGACC CCATCAACCA GAGAGCCTGC 
CACATCCTGG AGTGCTGTGA GGGCCTGGCA CAGAGCATCA TCAGCACCGT GGGCCAAGCT 
TTCGAGCTGC GCTTCAAGCA GTACCTGCAC AGCCCGCCCA AGGTGGCGCT GCCCCCAGAA 
AGGCTGGCAG GGCCGGAGGA GTCGGCCTGG GGGGACGAGG AGGACTCTTT GGAGCACAAT 
TACTACAACA GCATCCCGGG GAAGGAGCCG CCGCTGGGCG GGCTAGTGGA CTCCAGGCTG 
GCCCTGACAC AGCCCTGCGC CCTCACGGCC CTCGACCAGG GCCCATCTCC TTCTCTAAGA 
GATGCCTGCA GCCTGCCATG GGACGTGGGG TCCACCGGTA CAGCTCCACC GGGGGACGGC 
TACGTGCAGG CGGACGCCCG GGGCCCCCCG GACCACGAGG AGCACCTGTA TGTCAACACC 
CAGGGTCTGG ACGCCCCCGA GCCGGAGGAC AGCCCCAAAA AGGATCTGTT TGACATGCGA 
CCCTTTGAGG ATGCCCTGAA GTTGCATGAG TGCTCAGTGG CGGCAGGCGT GACAGCAGCC 
CCTCTTCCCT TGGAGGACCA GTGGCCCAGC CCCCCTACCC GCCGGGCCCC TGTGGCCCCC 
ACGGAGGAAC AGCTGCGTCA GGAGCCCTGG TACCACGGCC GGATGAGCCG CCGGGCGGCA 
GAGAGGATGC TTCGAGCTGA CGGGGACTTC CTTGTGCGAG ACAGCGTCAC CAACCCCGGG 
CAGTATGTCC TCACCGGCAT GCACGCCGGG CAGCCCAAGC ACCTGCTGCT CGTGGACCCC 
GAGGGCGTGG TAAGCTGTGC ACAGGTGGGA GGGTCTCGGG GCATCCAGGG GCTTCGCTGG 
GCACAGGTGG GAGGGTCTCA AGGGTCTCGA GGGTCTCGGG GCATGCAGGA GCTTTCCATG 
TTTATGAAGT TTTTCCAGAT TGTTCCAGAT GTTGCCTTTG ACCAGCTACT GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SHC2 ( XM_011527896.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011526198.1 Homo sapiens SHC adaptor protein 2 (SHC2), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu66461
Clone ID Related Accession (Same CDS sequence)	XM_017026567.1 , XM_011527896.2
Accession Version	XM_011527896.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1314bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	SHC-transforming protein 2 isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011527896.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCTGCA TCGAGGTTCT CCGCTCTATG CGCTCCCTGG ACTTTAACAC GCGCACGCAG 
GTGACCAGGG AAGCCATCAA CCGGCTCCAT GAGGCCGTGC CTGGCGTCCG GGGATCCTGG 
AAGAAAAAGG CCCCCAACAA GGCCCTGGCG TCCGTCCTGG GCAAGAGCAA CCTTCGCTTT 
GCCGGCATGA GCATCTCCAT CCACATCTCC ACTGATGGCC TCAGCCTCTC CGTGCCTGCC 
ACGCGCCAGG TCATCGCCAA CCACCACATG CCGTCCATCT CCTTCGCGTC AGGCGGAGAC 
ACGGACATGA CGGATTACGT GGCCTACGTC GCCAAGGACC CCATCAACCA GAGAGCCTGC 
CACATCCTGG AGTGCTGTGA GGGCCTGGCA CAGAGCATCA TCAGCACCGT GGGCCAAGCT 
TTCGAGCTGC GCTTCAAGCA GTACCTGCAC AGCCCGCCCA AGGTGGCGCT GCCCCCAGAA 
AGGCTGGCAG GGCCGGAGGA GTCGGCCTGG GGGGACGAGG AGGACTCTTT GGAGCACAAT 
TACTACAACA GCATCCCGGG GAAGGAGCCG CCGCTGGGCG GGCTAGTGGA CTCCAGGCTG 
GCCCTGACAC AGCCCTGCGC CCTCACGGCC CTCGACCAGG GCCCATCTCC TTCTCTAAGA 
GATGCCTGCA GCCTGCCATG GGACGTGGGG TCCACCGGTA CAGCTCCACC GGGGGACGGC 
TACGTGCAGG CGGACGCCCG GGGCCCCCCG GACCACGAGG AGCACCTGTA TGTCAACACC 
CAGGGTCTGG ACGCCCCCGA GCCGGAGGAC AGCCCCAAAA AGGATCTGTT TGACATGCGA 
CCCTTTGAGG ATGCCCTGAA GTTGCATGAG TGCTCAGTGG CGGCAGGCGT GACAGCAGCC 
CCTCTTCCCT TGGAGGACCA GTGGCCCAGC CCCCCTACCC GCCGGGCCCC TGTGGCCCCC 
ACGGAGGAAC AGCTGCGTCA GGAGCCCTGG TACCACGGCC GGATGAGCCG CCGGGCGGCA 
GAGAGGATGC TTCGAGCTGA CGGGGACTTC CTTGTGCGAG ACAGCGTCAC CAACCCCGGG 
CAGTATGTCC TCACCGGCAT GCACGCCGGG CAGCCCAAGC ACCTGCTGCT CGTGGACCCC 
GAGGGCGTGG TAAGCTGTGC ACAGGTGGGA GGGTCTCGGG GCATCCAGGG GCTTCGCTGG 
GCACAGGTGG GAGGGTCTCA AGGGTCTCGA GGGTCTCGGG GCATGCAGGA GCTTTCCATG 
TTTATGAAGT TTTTCCAGAT TGTTCCAGAT GTTGCCTTTG ACCAGCTACT GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011526198.1
CDS	532..1845
Translation	MGCIEVLRSMRSLDFNTRTQVTREAINRLHEAVPGVRGSWKKKAPNKALASVLGKSNLRFAGMSISIHISTDGLSLSVPATRQVIANHHMPSISFASGGDTDMTDYVAYVAKDPINQRACHILECCEGLAQSIISTVGQAFELRFKQYLHSPPKVALPPERLAGPEESAWGDEEDSLEHNYYNSIPGKEPPLGGLVDSRLALTQPCALTALDQGPSPSLRDACSLPWDVGSTGTAPPGDGYVQADARGPPDHEEHLYVNTQGLDAPEPEDSPKKDLFDMRPFEDALKLHECSVAAGVTAAPLPLEDQWPSPPTRRAPVAPTEEQLRQEPWYHGRMSRRAAERMLRADGDFLVRDSVTNPGQYVLTGMHAGQPKHLLLVDPEGVVSCAQVGGSRGIQGLRWAQVGGSQGSRGSRGMQELSMFMKFFQIVPDVAFDQLL

Target ORF information:

RefSeq Version	XM_011527896.2
Organism	Homo sapiens(human)
Definition	Homo sapiens SHC adaptor protein 2 (SHC2), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011527896.2

ORF Insert Sequence:

ATGGGCTGCA TCGAGGTTCT CCGCTCTATG CGCTCCCTGG ACTTTAACAC GCGCACGCAG 
GTGACCAGGG AAGCCATCAA CCGGCTCCAT GAGGCCGTGC CTGGCGTCCG GGGATCCTGG 
AAGAAAAAGG CCCCCAACAA GGCCCTGGCG TCCGTCCTGG GCAAGAGCAA CCTTCGCTTT 
GCCGGCATGA GCATCTCCAT CCACATCTCC ACTGATGGCC TCAGCCTCTC CGTGCCTGCC 
ACGCGCCAGG TCATCGCCAA CCACCACATG CCGTCCATCT CCTTCGCGTC AGGCGGAGAC 
ACGGACATGA CGGATTACGT GGCCTACGTC GCCAAGGACC CCATCAACCA GAGAGCCTGC 
CACATCCTGG AGTGCTGTGA GGGCCTGGCA CAGAGCATCA TCAGCACCGT GGGCCAAGCT 
TTCGAGCTGC GCTTCAAGCA GTACCTGCAC AGCCCGCCCA AGGTGGCGCT GCCCCCAGAA 
AGGCTGGCAG GGCCGGAGGA GTCGGCCTGG GGGGACGAGG AGGACTCTTT GGAGCACAAT 
TACTACAACA GCATCCCGGG GAAGGAGCCG CCGCTGGGCG GGCTAGTGGA CTCCAGGCTG 
GCCCTGACAC AGCCCTGCGC CCTCACGGCC CTCGACCAGG GCCCATCTCC TTCTCTAAGA 
GATGCCTGCA GCCTGCCATG GGACGTGGGG TCCACCGGTA CAGCTCCACC GGGGGACGGC 
TACGTGCAGG CGGACGCCCG GGGCCCCCCG GACCACGAGG AGCACCTGTA TGTCAACACC 
CAGGGTCTGG ACGCCCCCGA GCCGGAGGAC AGCCCCAAAA AGGATCTGTT TGACATGCGA 
CCCTTTGAGG ATGCCCTGAA GTTGCATGAG TGCTCAGTGG CGGCAGGCGT GACAGCAGCC 
CCTCTTCCCT TGGAGGACCA GTGGCCCAGC CCCCCTACCC GCCGGGCCCC TGTGGCCCCC 
ACGGAGGAAC AGCTGCGTCA GGAGCCCTGG TACCACGGCC GGATGAGCCG CCGGGCGGCA 
GAGAGGATGC TTCGAGCTGA CGGGGACTTC CTTGTGCGAG ACAGCGTCAC CAACCCCGGG 
CAGTATGTCC TCACCGGCAT GCACGCCGGG CAGCCCAAGC ACCTGCTGCT CGTGGACCCC 
GAGGGCGTGG TAAGCTGTGC ACAGGTGGGA GGGTCTCGGG GCATCCAGGG GCTTCGCTGG 
GCACAGGTGG GAGGGTCTCA AGGGTCTCGA GGGTCTCGGG GCATGCAGGA GCTTTCCATG 
TTTATGAAGT TTTTCCAGAT TGTTCCAGAT GTTGCCTTTG ACCAGCTACT GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SHC2 ( NM_012435.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_036567.2 Homo sapiens SHC adaptor protein 2 (SHC2), mRNA.

Price & Availability↑

CloneID	OHu31440
Clone ID Related Accession (Same CDS sequence)	NM_012435.2
Accession Version	NM_012435.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1749bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-04
Organism	Homo sapiens(human)
Product	SHC-transforming protein 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC006124.2, AB001451.1, AL360254.1, BC048290.1, BQ025513.1 and CK826553.1. On Mar 12, 2008 this sequence version replaced NM_012435.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by orthologous data. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB001451.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END##

ATGACGCAGG GTCCGGGCGG GCGCGCGCCC CCGGCGCCCC CCGCGCCCCC CGAGCCCGAG 
GCGCCCACCA CCTTCTGCGC GTTGCTGCCC CGAATGCCGC AGTGGAAGTT CGCGGCCCCG 
GGCGGCTTCC TGGGCCGCGG CCCGGCGGCG GCGCGGGCGG CTGGGGCCTC GGGGGGCGCG 
GACCCCCAAC CCGAGCCGGC GGGCCCGGGG GGCGTCCCGG CGCTGGCGGC CGCCGTCCTG 
GGCGCCTGCG AGCCCCGCTG CGCCGCGCCC TGTCCCCTGC CCGCGCTCAG CCGCTGTCGG 
GGCGCGGGGT CGCGGGGGTC GCGGGGCGGG CGGGGGGCGG CGGGGTCCGG GGACGCCGCC 
GCCGCCGCCG AGTGGATCCG GAAGGGCAGC TTCATCCACA AACCCGCGCA CGGCTGGCTA 
CACCCCGACG CCAGGGTCCT GGGGCCCGGG GTCTCCTACG TCGTGCGGTA CATGGGCTGC 
ATCGAGGTTC TCCGCTCTAT GCGCTCCCTG GACTTTAACA CGCGCACGCA GGTGACCAGG 
GAAGCCATCA ACCGGCTCCA TGAGGCCGTG CCTGGCGTCC GGGGATCCTG GAAGAAAAAG 
GCCCCCAACA AGGCCCTGGC GTCCGTCCTG GGCAAGAGCA ACCTTCGCTT TGCCGGCATG 
AGCATCTCCA TCCACATCTC CACTGATGGC CTCAGCCTCT CCGTGCCTGC CACGCGCCAG 
GTCATCGCCA ACCACCACAT GCCGTCCATC TCCTTCGCGT CAGGCGGAGA CACGGACATG 
ACGGATTACG TGGCCTACGT CGCCAAGGAC CCCATCAACC AGAGAGCCTG CCACATCCTG 
GAGTGCTGTG AGGGCCTGGC ACAGAGCATC ATCAGCACCG TGGGCCAAGC TTTCGAGCTG 
CGCTTCAAGC AGTACCTGCA CAGCCCGCCC AAGGTGGCGC TGCCCCCAGA AAGGCTGGCA 
GGGCCGGAGG AGTCGGCCTG GGGGGACGAG GAGGACTCTT TGGAGCACAA TTACTACAAC 
AGCATCCCGG GGAAGGAGCC GCCGCTGGGC GGGCTAGTGG ACTCCAGGCT GGCCCTGACA 
CAGCCCTGCG CCCTCACGGC CCTCGACCAG GGCCCATCTC CTTCTCTAAG AGATGCCTGC 
AGCCTGCCAT GGGACGTGGG GTCCACCGGT ACAGCTCCAC CGGGGGACGG CTACGTGCAG 
GCGGACGCCC GGGGCCCCCC GGACCACGAG GAGCACCTGT ATGTCAACAC CCAGGGTCTG 
GACGCCCCCG AGCCGGAGGA CAGCCCCAAA AAGGATCTGT TTGACATGCG ACCCTTTGAG 
GATGCCCTGA AGTTGCATGA GTGCTCAGTG GCGGCAGGCG TGACAGCAGC CCCTCTTCCC 
TTGGAGGACC AGTGGCCCAG CCCCCCTACC CGCCGGGCCC CTGTGGCCCC CACGGAGGAA 
CAGCTGCGTC AGGAGCCCTG GTACCACGGC CGGATGAGCC GCCGGGCGGC AGAGAGGATG 
CTTCGAGCTG ACGGGGACTT CCTTGTGCGA GACAGCGTCA CCAACCCCGG GCAGTATGTC 
CTCACCGGCA TGCACGCCGG GCAGCCCAAG CACCTGCTGC TCGTGGACCC CGAGGGCGTG 
GTACGGACGA AGGACGTGCT GTTTGAGAGC ATCAGCCACC TGATCGACCA CCACCTGCAG 
AACGGGCAGC CCATCGTGGC CGCCGAGAGT GAGCTGCACC TGCGTGGCGT GGTCTCACGG 
GAGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036567.2
CDS	1..1749
Translation	MTQGPGGRAPPAPPAPPEPEAPTTFCALLPRMPQWKFAAPGGFLGRGPAAARAAGASGGADPQPEPAGPGGVPALAAAVLGACEPRCAAPCPLPALSRCRGAGSRGSRGGRGAAGSGDAAAAAEWIRKGSFIHKPAHGWLHPDARVLGPGVSYVVRYMGCIEVLRSMRSLDFNTRTQVTREAINRLHEAVPGVRGSWKKKAPNKALASVLGKSNLRFAGMSISIHISTDGLSLSVPATRQVIANHHMPSISFASGGDTDMTDYVAYVAKDPINQRACHILECCEGLAQSIISTVGQAFELRFKQYLHSPPKVALPPERLAGPEESAWGDEEDSLEHNYYNSIPGKEPPLGGLVDSRLALTQPCALTALDQGPSPSLRDACSLPWDVGSTGTAPPGDGYVQADARGPPDHEEHLYVNTQGLDAPEPEDSPKKDLFDMRPFEDALKLHECSVAAGVTAAPLPLEDQWPSPPTRRAPVAPTEEQLRQEPWYHGRMSRRAAERMLRADGDFLVRDSVTNPGQYVLTGMHAGQPKHLLLVDPEGVVRTKDVLFESISHLIDHHLQNGQPIVAAESELHLRGVVSREP

Target ORF information:

RefSeq Version	NM_012435.2
Organism	Homo sapiens(human)
Definition	Homo sapiens SHC adaptor protein 2 (SHC2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012435.2

ORF Insert Sequence:

ATGACGCAGG GTCCGGGCGG GCGCGCGCCC CCGGCGCCCC CCGCGCCCCC CGAGCCCGAG 
GCGCCCACCA CCTTCTGCGC GTTGCTGCCC CGAATGCCGC AGTGGAAGTT CGCGGCCCCG 
GGCGGCTTCC TGGGCCGCGG CCCGGCGGCG GCGCGGGCGG CTGGGGCCTC GGGGGGCGCG 
GACCCCCAAC CCGAGCCGGC GGGCCCGGGG GGCGTCCCGG CGCTGGCGGC CGCCGTCCTG 
GGCGCCTGCG AGCCCCGCTG CGCCGCGCCC TGTCCCCTGC CCGCGCTCAG CCGCTGTCGG 
GGCGCGGGGT CGCGGGGGTC GCGGGGCGGG CGGGGGGCGG CGGGGTCCGG GGACGCCGCC 
GCCGCCGCCG AGTGGATCCG GAAGGGCAGC TTCATCCACA AACCCGCGCA CGGCTGGCTA 
CACCCCGACG CCAGGGTCCT GGGGCCCGGG GTCTCCTACG TCGTGCGGTA CATGGGCTGC 
ATCGAGGTTC TCCGCTCTAT GCGCTCCCTG GACTTTAACA CGCGCACGCA GGTGACCAGG 
GAAGCCATCA ACCGGCTCCA TGAGGCCGTG CCTGGCGTCC GGGGATCCTG GAAGAAAAAG 
GCCCCCAACA AGGCCCTGGC GTCCGTCCTG GGCAAGAGCA ACCTTCGCTT TGCCGGCATG 
AGCATCTCCA TCCACATCTC CACTGATGGC CTCAGCCTCT CCGTGCCTGC CACGCGCCAG 
GTCATCGCCA ACCACCACAT GCCGTCCATC TCCTTCGCGT CAGGCGGAGA CACGGACATG 
ACGGATTACG TGGCCTACGT CGCCAAGGAC CCCATCAACC AGAGAGCCTG CCACATCCTG 
GAGTGCTGTG AGGGCCTGGC ACAGAGCATC ATCAGCACCG TGGGCCAAGC TTTCGAGCTG 
CGCTTCAAGC AGTACCTGCA CAGCCCGCCC AAGGTGGCGC TGCCCCCAGA AAGGCTGGCA 
GGGCCGGAGG AGTCGGCCTG GGGGGACGAG GAGGACTCTT TGGAGCACAA TTACTACAAC 
AGCATCCCGG GGAAGGAGCC GCCGCTGGGC GGGCTAGTGG ACTCCAGGCT GGCCCTGACA 
CAGCCCTGCG CCCTCACGGC CCTCGACCAG GGCCCATCTC CTTCTCTAAG AGATGCCTGC 
AGCCTGCCAT GGGACGTGGG GTCCACCGGT ACAGCTCCAC CGGGGGACGG CTACGTGCAG 
GCGGACGCCC GGGGCCCCCC GGACCACGAG GAGCACCTGT ATGTCAACAC CCAGGGTCTG 
GACGCCCCCG AGCCGGAGGA CAGCCCCAAA AAGGATCTGT TTGACATGCG ACCCTTTGAG 
GATGCCCTGA AGTTGCATGA GTGCTCAGTG GCGGCAGGCG TGACAGCAGC CCCTCTTCCC 
TTGGAGGACC AGTGGCCCAG CCCCCCTACC CGCCGGGCCC CTGTGGCCCC CACGGAGGAA 
CAGCTGCGTC AGGAGCCCTG GTACCACGGC CGGATGAGCC GCCGGGCGGC AGAGAGGATG 
CTTCGAGCTG ACGGGGACTT CCTTGTGCGA GACAGCGTCA CCAACCCCGG GCAGTATGTC 
CTCACCGGCA TGCACGCCGG GCAGCCCAAG CACCTGCTGC TCGTGGACCC CGAGGGCGTG 
GTACGGACGA AGGACGTGCT GTTTGAGAGC ATCAGCCACC TGATCGACCA CCACCTGCAG 
AACGGGCAGC CCATCGTGGC CGCCGAGAGT GAGCTGCACC TGCGTGGCGT GGTCTCACGG 
GAGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SHC2 ( XM_011527893.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011526195.1 Homo sapiens SHC adaptor protein 2 (SHC2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu66458
Clone ID Related Accession (Same CDS sequence)	XM_011527893.3 , XM_011527893.2
Accession Version	XM_011527893.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1785bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	SHC-transforming protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011527893.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACGCAGG GTCCGGGCGG GCGCGCGCCC CCGGCGCCCC CCGCGCCCCC CGAGCCCGAG 
GCGCCCACCA CCTTCTGCGC GTTGCTGCCC CGAATGCCGC AGTGGAAGTT CGCGGCCCCG 
GGCGGCTTCC TGGGCCGCGG CCCGGCGGCG GCGCGGGCGG CTGGGGCCTC GGGGGGCGCG 
GACCCCCAAC CCGAGCCGGC GGGCCCGGGG GGCGTCCCGG CGCTGGCGGC CGCCGTCCTG 
GGCGCCTGCG AGCCCCGCTG CGCCGCGCCC TGTCCCCTGC CCGCGCTCAG CCGCTGTCGG 
GGCGCGGGGT CGCGGGGGTC GCGGGGCGGG CGGGGGGCGG CGGGGTCCGG GGACGCCGCC 
GCCGCCGCCG AGTGGATCCG GAAGGGCAGC TTCATCCACA AACCCGCGCA CGGCTGGCTA 
CACCCCGACG CCAGGGTCCT GGGGCCCGGG GTCTCCTACG TCGTGCGGTA CATGGGCTGC 
ATCGAGGTTC TCCGCTCTAT GCGCTCCCTG GACTTTAACA CGCGCACGCA GGTGACCAGG 
GAAGCCATCA ACCGGCTCCA TGAGGCCGTG CCTGGCGTCC GGGGATCCTG GAAGAAAAAG 
GCCCCCAACA AGGCCCTGGC GTCCGTCCTG GGCAAGAGCA ACCTTCGCTT TGCCGGCATG 
AGCATCTCCA TCCACATCTC CACTGATGGC CTCAGCCTCT CCGTGCCTGC CACGCGCCAG 
GTCATCGCCA ACCACCACAT GCCGTCCATC TCCTTCGCGT CAGGCGGAGA CACGGACATG 
ACGGATTACG TGGCCTACGT CGCCAAGGAC CCCATCAACC AGAGAGCCTG CCACATCCTG 
GAGTGCTGTG AGGGCCTGGC ACAGAGCATC ATCAGCACCG TGGGCCAAGC TTTCGAGCTG 
CGCTTCAAGC AGTACCTGCA CAGCCCGCCC AAGGTGGCGC TGCCCCCAGA AAGGCTGGCA 
GGGCCGGAGG AGTCGGCCTG GGGGGACGAG GAGGACTCTT TGGAGCACAA TTACTACAAC 
AGCATCCCGG GGAAGGAGCC GCCGCTGGGC GGGCTAGTGG ACTCCAGGCT GGCCCTGACA 
CAGCCCTGCG CCCTCACGGC CCTCGACCAG GGCCCATCTC CTTCTCTAAG AGATGCCTGC 
AGCCTGCCAT GGGACGTGGG GTCCACCGGT ACAGCTCCAC CGGGGGACGG CTACGTGCAG 
GCGGACGCCC GGGGCCCCCC GGACCACGAG GAGCACCTGT ATGTCAACAC CCAGGGTCTG 
GACGCCCCCG AGCCGGAGGA CAGCCCCAAA AAGGATCTGT TTGACATGCG ACCCTTTGAG 
GATGCCCTGA AGTTGCATGA GTGCTCAGTG GCGGCAGGCG TGACAGCAGC CCCTCTTCCC 
TTGGAGGACC AGTGGCCCAG CCCCCCTACC CGCCGGGCCC CTGTGGCCCC CACGGAGGAA 
CAGCTGCGTC AGGAGCCCTG GTACCACGGC CGGATGAGCC GCCGGGCGGC AGAGAGGATG 
CTTCGAGCTG ACGGGGACTT CCTTGTGCGA GACAGCGTCA CCAACCCCGG GCAGTATGTC 
CTCACCGGCA TGCACGCCGG GCAGCCCAAG CACCTGCTGC TCGTGGACCC CGAGGGCGTG 
GTAAGCTGTG CACAGGTGGG AGGGTCTCGG GGCATCCAGG GGCTTCGCTG GGCACAGGTG 
GGAGGGTCTC AAGGGTCTCG AGGGTCTCGG GGCATGCAGG AGCTTTCCAT GTTTATGAAG 
TTTTTCCAGA TTGTTCCAGA TGTTGCCTTT GACCAGCTAC TGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011526195.1
CDS	16..1800
Translation	MTQGPGGRAPPAPPAPPEPEAPTTFCALLPRMPQWKFAAPGGFLGRGPAAARAAGASGGADPQPEPAGPGGVPALAAAVLGACEPRCAAPCPLPALSRCRGAGSRGSRGGRGAAGSGDAAAAAEWIRKGSFIHKPAHGWLHPDARVLGPGVSYVVRYMGCIEVLRSMRSLDFNTRTQVTREAINRLHEAVPGVRGSWKKKAPNKALASVLGKSNLRFAGMSISIHISTDGLSLSVPATRQVIANHHMPSISFASGGDTDMTDYVAYVAKDPINQRACHILECCEGLAQSIISTVGQAFELRFKQYLHSPPKVALPPERLAGPEESAWGDEEDSLEHNYYNSIPGKEPPLGGLVDSRLALTQPCALTALDQGPSPSLRDACSLPWDVGSTGTAPPGDGYVQADARGPPDHEEHLYVNTQGLDAPEPEDSPKKDLFDMRPFEDALKLHECSVAAGVTAAPLPLEDQWPSPPTRRAPVAPTEEQLRQEPWYHGRMSRRAAERMLRADGDFLVRDSVTNPGQYVLTGMHAGQPKHLLLVDPEGVVSCAQVGGSRGIQGLRWAQVGGSQGSRGSRGMQELSMFMKFFQIVPDVAFDQLL

Target ORF information:

RefSeq Version	XM_011527893.3
Organism	Homo sapiens(human)
Definition	Homo sapiens SHC adaptor protein 2 (SHC2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011527893.3

ORF Insert Sequence:

ATGACGCAGG GTCCGGGCGG GCGCGCGCCC CCGGCGCCCC CCGCGCCCCC CGAGCCCGAG 
GCGCCCACCA CCTTCTGCGC GTTGCTGCCC CGAATGCCGC AGTGGAAGTT CGCGGCCCCG 
GGCGGCTTCC TGGGCCGCGG CCCGGCGGCG GCGCGGGCGG CTGGGGCCTC GGGGGGCGCG 
GACCCCCAAC CCGAGCCGGC GGGCCCGGGG GGCGTCCCGG CGCTGGCGGC CGCCGTCCTG 
GGCGCCTGCG AGCCCCGCTG CGCCGCGCCC TGTCCCCTGC CCGCGCTCAG CCGCTGTCGG 
GGCGCGGGGT CGCGGGGGTC GCGGGGCGGG CGGGGGGCGG CGGGGTCCGG GGACGCCGCC 
GCCGCCGCCG AGTGGATCCG GAAGGGCAGC TTCATCCACA AACCCGCGCA CGGCTGGCTA 
CACCCCGACG CCAGGGTCCT GGGGCCCGGG GTCTCCTACG TCGTGCGGTA CATGGGCTGC 
ATCGAGGTTC TCCGCTCTAT GCGCTCCCTG GACTTTAACA CGCGCACGCA GGTGACCAGG 
GAAGCCATCA ACCGGCTCCA TGAGGCCGTG CCTGGCGTCC GGGGATCCTG GAAGAAAAAG 
GCCCCCAACA AGGCCCTGGC GTCCGTCCTG GGCAAGAGCA ACCTTCGCTT TGCCGGCATG 
AGCATCTCCA TCCACATCTC CACTGATGGC CTCAGCCTCT CCGTGCCTGC CACGCGCCAG 
GTCATCGCCA ACCACCACAT GCCGTCCATC TCCTTCGCGT CAGGCGGAGA CACGGACATG 
ACGGATTACG TGGCCTACGT CGCCAAGGAC CCCATCAACC AGAGAGCCTG CCACATCCTG 
GAGTGCTGTG AGGGCCTGGC ACAGAGCATC ATCAGCACCG TGGGCCAAGC TTTCGAGCTG 
CGCTTCAAGC AGTACCTGCA CAGCCCGCCC AAGGTGGCGC TGCCCCCAGA AAGGCTGGCA 
GGGCCGGAGG AGTCGGCCTG GGGGGACGAG GAGGACTCTT TGGAGCACAA TTACTACAAC 
AGCATCCCGG GGAAGGAGCC GCCGCTGGGC GGGCTAGTGG ACTCCAGGCT GGCCCTGACA 
CAGCCCTGCG CCCTCACGGC CCTCGACCAG GGCCCATCTC CTTCTCTAAG AGATGCCTGC 
AGCCTGCCAT GGGACGTGGG GTCCACCGGT ACAGCTCCAC CGGGGGACGG CTACGTGCAG 
GCGGACGCCC GGGGCCCCCC GGACCACGAG GAGCACCTGT ATGTCAACAC CCAGGGTCTG 
GACGCCCCCG AGCCGGAGGA CAGCCCCAAA AAGGATCTGT TTGACATGCG ACCCTTTGAG 
GATGCCCTGA AGTTGCATGA GTGCTCAGTG GCGGCAGGCG TGACAGCAGC CCCTCTTCCC 
TTGGAGGACC AGTGGCCCAG CCCCCCTACC CGCCGGGCCC CTGTGGCCCC CACGGAGGAA 
CAGCTGCGTC AGGAGCCCTG GTACCACGGC CGGATGAGCC GCCGGGCGGC AGAGAGGATG 
CTTCGAGCTG ACGGGGACTT CCTTGTGCGA GACAGCGTCA CCAACCCCGG GCAGTATGTC 
CTCACCGGCA TGCACGCCGG GCAGCCCAAG CACCTGCTGC TCGTGGACCC CGAGGGCGTG 
GTAAGCTGTG CACAGGTGGG AGGGTCTCGG GGCATCCAGG GGCTTCGCTG GGCACAGGTG 
GGAGGGTCTC AAGGGTCTCG AGGGTCTCGG GGCATGCAGG AGCTTTCCAT GTTTATGAAG 
TTTTTCCAGA TTGTTCCAGA TGTTGCCTTT GACCAGCTAC TGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SHC2 ( XM_011527893.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011526195.1 Homo sapiens SHC adaptor protein 2 (SHC2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu66458
Clone ID Related Accession (Same CDS sequence)	XM_011527893.3 , XM_011527893.2
Accession Version	XM_011527893.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1785bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	SHC-transforming protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011527893.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACGCAGG GTCCGGGCGG GCGCGCGCCC CCGGCGCCCC CCGCGCCCCC CGAGCCCGAG 
GCGCCCACCA CCTTCTGCGC GTTGCTGCCC CGAATGCCGC AGTGGAAGTT CGCGGCCCCG 
GGCGGCTTCC TGGGCCGCGG CCCGGCGGCG GCGCGGGCGG CTGGGGCCTC GGGGGGCGCG 
GACCCCCAAC CCGAGCCGGC GGGCCCGGGG GGCGTCCCGG CGCTGGCGGC CGCCGTCCTG 
GGCGCCTGCG AGCCCCGCTG CGCCGCGCCC TGTCCCCTGC CCGCGCTCAG CCGCTGTCGG 
GGCGCGGGGT CGCGGGGGTC GCGGGGCGGG CGGGGGGCGG CGGGGTCCGG GGACGCCGCC 
GCCGCCGCCG AGTGGATCCG GAAGGGCAGC TTCATCCACA AACCCGCGCA CGGCTGGCTA 
CACCCCGACG CCAGGGTCCT GGGGCCCGGG GTCTCCTACG TCGTGCGGTA CATGGGCTGC 
ATCGAGGTTC TCCGCTCTAT GCGCTCCCTG GACTTTAACA CGCGCACGCA GGTGACCAGG 
GAAGCCATCA ACCGGCTCCA TGAGGCCGTG CCTGGCGTCC GGGGATCCTG GAAGAAAAAG 
GCCCCCAACA AGGCCCTGGC GTCCGTCCTG GGCAAGAGCA ACCTTCGCTT TGCCGGCATG 
AGCATCTCCA TCCACATCTC CACTGATGGC CTCAGCCTCT CCGTGCCTGC CACGCGCCAG 
GTCATCGCCA ACCACCACAT GCCGTCCATC TCCTTCGCGT CAGGCGGAGA CACGGACATG 
ACGGATTACG TGGCCTACGT CGCCAAGGAC CCCATCAACC AGAGAGCCTG CCACATCCTG 
GAGTGCTGTG AGGGCCTGGC ACAGAGCATC ATCAGCACCG TGGGCCAAGC TTTCGAGCTG 
CGCTTCAAGC AGTACCTGCA CAGCCCGCCC AAGGTGGCGC TGCCCCCAGA AAGGCTGGCA 
GGGCCGGAGG AGTCGGCCTG GGGGGACGAG GAGGACTCTT TGGAGCACAA TTACTACAAC 
AGCATCCCGG GGAAGGAGCC GCCGCTGGGC GGGCTAGTGG ACTCCAGGCT GGCCCTGACA 
CAGCCCTGCG CCCTCACGGC CCTCGACCAG GGCCCATCTC CTTCTCTAAG AGATGCCTGC 
AGCCTGCCAT GGGACGTGGG GTCCACCGGT ACAGCTCCAC CGGGGGACGG CTACGTGCAG 
GCGGACGCCC GGGGCCCCCC GGACCACGAG GAGCACCTGT ATGTCAACAC CCAGGGTCTG 
GACGCCCCCG AGCCGGAGGA CAGCCCCAAA AAGGATCTGT TTGACATGCG ACCCTTTGAG 
GATGCCCTGA AGTTGCATGA GTGCTCAGTG GCGGCAGGCG TGACAGCAGC CCCTCTTCCC 
TTGGAGGACC AGTGGCCCAG CCCCCCTACC CGCCGGGCCC CTGTGGCCCC CACGGAGGAA 
CAGCTGCGTC AGGAGCCCTG GTACCACGGC CGGATGAGCC GCCGGGCGGC AGAGAGGATG 
CTTCGAGCTG ACGGGGACTT CCTTGTGCGA GACAGCGTCA CCAACCCCGG GCAGTATGTC 
CTCACCGGCA TGCACGCCGG GCAGCCCAAG CACCTGCTGC TCGTGGACCC CGAGGGCGTG 
GTAAGCTGTG CACAGGTGGG AGGGTCTCGG GGCATCCAGG GGCTTCGCTG GGCACAGGTG 
GGAGGGTCTC AAGGGTCTCG AGGGTCTCGG GGCATGCAGG AGCTTTCCAT GTTTATGAAG 
TTTTTCCAGA TTGTTCCAGA TGTTGCCTTT GACCAGCTAC TGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011526195.1
CDS	16..1800
Translation	MTQGPGGRAPPAPPAPPEPEAPTTFCALLPRMPQWKFAAPGGFLGRGPAAARAAGASGGADPQPEPAGPGGVPALAAAVLGACEPRCAAPCPLPALSRCRGAGSRGSRGGRGAAGSGDAAAAAEWIRKGSFIHKPAHGWLHPDARVLGPGVSYVVRYMGCIEVLRSMRSLDFNTRTQVTREAINRLHEAVPGVRGSWKKKAPNKALASVLGKSNLRFAGMSISIHISTDGLSLSVPATRQVIANHHMPSISFASGGDTDMTDYVAYVAKDPINQRACHILECCEGLAQSIISTVGQAFELRFKQYLHSPPKVALPPERLAGPEESAWGDEEDSLEHNYYNSIPGKEPPLGGLVDSRLALTQPCALTALDQGPSPSLRDACSLPWDVGSTGTAPPGDGYVQADARGPPDHEEHLYVNTQGLDAPEPEDSPKKDLFDMRPFEDALKLHECSVAAGVTAAPLPLEDQWPSPPTRRAPVAPTEEQLRQEPWYHGRMSRRAAERMLRADGDFLVRDSVTNPGQYVLTGMHAGQPKHLLLVDPEGVVSCAQVGGSRGIQGLRWAQVGGSQGSRGSRGMQELSMFMKFFQIVPDVAFDQLL

Target ORF information:

RefSeq Version	XM_011527893.2
Organism	Homo sapiens(human)
Definition	Homo sapiens SHC adaptor protein 2 (SHC2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011527893.2

ORF Insert Sequence:

ATGACGCAGG GTCCGGGCGG GCGCGCGCCC CCGGCGCCCC CCGCGCCCCC CGAGCCCGAG 
GCGCCCACCA CCTTCTGCGC GTTGCTGCCC CGAATGCCGC AGTGGAAGTT CGCGGCCCCG 
GGCGGCTTCC TGGGCCGCGG CCCGGCGGCG GCGCGGGCGG CTGGGGCCTC GGGGGGCGCG 
GACCCCCAAC CCGAGCCGGC GGGCCCGGGG GGCGTCCCGG CGCTGGCGGC CGCCGTCCTG 
GGCGCCTGCG AGCCCCGCTG CGCCGCGCCC TGTCCCCTGC CCGCGCTCAG CCGCTGTCGG 
GGCGCGGGGT CGCGGGGGTC GCGGGGCGGG CGGGGGGCGG CGGGGTCCGG GGACGCCGCC 
GCCGCCGCCG AGTGGATCCG GAAGGGCAGC TTCATCCACA AACCCGCGCA CGGCTGGCTA 
CACCCCGACG CCAGGGTCCT GGGGCCCGGG GTCTCCTACG TCGTGCGGTA CATGGGCTGC 
ATCGAGGTTC TCCGCTCTAT GCGCTCCCTG GACTTTAACA CGCGCACGCA GGTGACCAGG 
GAAGCCATCA ACCGGCTCCA TGAGGCCGTG CCTGGCGTCC GGGGATCCTG GAAGAAAAAG 
GCCCCCAACA AGGCCCTGGC GTCCGTCCTG GGCAAGAGCA ACCTTCGCTT TGCCGGCATG 
AGCATCTCCA TCCACATCTC CACTGATGGC CTCAGCCTCT CCGTGCCTGC CACGCGCCAG 
GTCATCGCCA ACCACCACAT GCCGTCCATC TCCTTCGCGT CAGGCGGAGA CACGGACATG 
ACGGATTACG TGGCCTACGT CGCCAAGGAC CCCATCAACC AGAGAGCCTG CCACATCCTG 
GAGTGCTGTG AGGGCCTGGC ACAGAGCATC ATCAGCACCG TGGGCCAAGC TTTCGAGCTG 
CGCTTCAAGC AGTACCTGCA CAGCCCGCCC AAGGTGGCGC TGCCCCCAGA AAGGCTGGCA 
GGGCCGGAGG AGTCGGCCTG GGGGGACGAG GAGGACTCTT TGGAGCACAA TTACTACAAC 
AGCATCCCGG GGAAGGAGCC GCCGCTGGGC GGGCTAGTGG ACTCCAGGCT GGCCCTGACA 
CAGCCCTGCG CCCTCACGGC CCTCGACCAG GGCCCATCTC CTTCTCTAAG AGATGCCTGC 
AGCCTGCCAT GGGACGTGGG GTCCACCGGT ACAGCTCCAC CGGGGGACGG CTACGTGCAG 
GCGGACGCCC GGGGCCCCCC GGACCACGAG GAGCACCTGT ATGTCAACAC CCAGGGTCTG 
GACGCCCCCG AGCCGGAGGA CAGCCCCAAA AAGGATCTGT TTGACATGCG ACCCTTTGAG 
GATGCCCTGA AGTTGCATGA GTGCTCAGTG GCGGCAGGCG TGACAGCAGC CCCTCTTCCC 
TTGGAGGACC AGTGGCCCAG CCCCCCTACC CGCCGGGCCC CTGTGGCCCC CACGGAGGAA 
CAGCTGCGTC AGGAGCCCTG GTACCACGGC CGGATGAGCC GCCGGGCGGC AGAGAGGATG 
CTTCGAGCTG ACGGGGACTT CCTTGTGCGA GACAGCGTCA CCAACCCCGG GCAGTATGTC 
CTCACCGGCA TGCACGCCGG GCAGCCCAAG CACCTGCTGC TCGTGGACCC CGAGGGCGTG 
GTAAGCTGTG CACAGGTGGG AGGGTCTCGG GGCATCCAGG GGCTTCGCTG GGCACAGGTG 
GGAGGGTCTC AAGGGTCTCG AGGGTCTCGG GGCATGCAGG AGCTTTCCAT GTTTATGAAG 
TTTTTCCAGA TTGTTCCAGA TGTTGCCTTT GACCAGCTAC TGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SHC2 ( XM_011527894.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011526196.1 Homo sapiens SHC adaptor protein 2 (SHC2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu66459
Clone ID Related Accession (Same CDS sequence)	XM_011527894.2
Accession Version	XM_011527894.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1650bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	SHC-transforming protein 2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011527894.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACGCAGG GTCCGGGCGG GCGCGCGCCC CCGGCGCCCC CCGCGCCCCC CGAGCCCGAG 
GCGCCCACCA CCTTCTGCGC GTTGCTGCCC CGAATGCCGC AGTGGAAGTT CGCGGCCCCG 
GGCGGCTTCC TGGGCCGCGG CCCGGCGGCG GCGCGGGCGG CTGGGGCCTC GGGGGGCGCG 
GACCCCCAAC CCGAGCCGGC GGGCCCGGGG GGCGTCCCGG CGCTGGCGGC CGCCGTCCTG 
GGCGCCTGCG AGCCCCGCTG CGCCGCGCCC TGTCCCCTGC CCGCGCTCAG CCGCTGTCGG 
GGCGCGGGGT CGCGGGGGTC GCGGGGCGGG CGGGGGGCGG CGGGGTCCGG GGACGCCGCC 
GCCGCCGCCG AGTGGATCCG GAAGGGCAGC TTCATCCACA AACCCGCGCA CGGCTGGCTA 
CACCCCGACG CCAGGGTCCT GGGGCCCGGG GTCTCCTACG TCGTGCGGTA CATGGGCTGC 
ATCGAGGTTC TCCGCTCTAT GCGCTCCCTG GACTTTAACA CGCGCACGCA GGTGACCAGG 
GAAGCCATCA ACCGGCTCCA TGAGGCCGTG CCTGGCGTCC GGGGATCCTG GAAGAAAAAG 
GCCCCCAACA AGGCCCTGGC GTCCGTCCTG GGCAAGAGCA ACCTTCGCTT TGCCGGCATG 
AGCATCTCCA TCCACATCTC CACTGATGGC CTCAGCCTCT CCGTGCCTGC CACGCGCCAG 
GTCATCGCCA ACCACCACAT GCCGTCCATC TCCTTCGCGT CAGGCGGAGA CACGGACATG 
ACGGATTACG TGGCCTACGT CGCCAAGGAC CCCATCAACC AGAGAGCCTG CCACATCCTG 
GAGTGCTGTG AGGGCCTGGC ACAGAGCATC ATCAGCACCG TGGGCCAAGC TTTCGAGCTG 
CGCTTCAAGC AGTACCTGCA CAGCCCGCCC AAGGTGGCGC TGCCCCCAGA AAGGCTGGCA 
GGGCCGGAGG AGTCGGCCTG GGGGGACGAG GAGGACTCTT TGGAGCACAA TTACTACAAC 
AGCATCCCGG GGAAGGAGCC GCCGCTGGGC GGGCTAGTGG ACTCCAGGCT GGCCCTGACA 
CAGCCCTGCG CCCTCACGGC CCTCGACCAG GGCCCATCTC CTTCTCTAAG AGATGCCTGC 
AGCCTGCCAT GGGACGTGGG GTCCACCGGT ACAGGACCCT TTGAGGATGC CCTGAAGTTG 
CATGAGTGCT CAGTGGCGGC AGGCGTGACA GCAGCCCCTC TTCCCTTGGA GGACCAGTGG 
CCCAGCCCCC CTACCCGCCG GGCCCCTGTG GCCCCCACGG AGGAACAGCT GCGTCAGGAG 
CCCTGGTACC ACGGCCGGAT GAGCCGCCGG GCGGCAGAGA GGATGCTTCG AGCTGACGGG 
GACTTCCTTG TGCGAGACAG CGTCACCAAC CCCGGGCAGT ATGTCCTCAC CGGCATGCAC 
GCCGGGCAGC CCAAGCACCT GCTGCTCGTG GACCCCGAGG GCGTGGTAAG CTGTGCACAG 
GTGGGAGGGT CTCGGGGCAT CCAGGGGCTT CGCTGGGCAC AGGTGGGAGG GTCTCAAGGG 
TCTCGAGGGT CTCGGGGCAT GCAGGAGCTT TCCATGTTTA TGAAGTTTTT CCAGATTGTT 
CCAGATGTTG CCTTTGACCA GCTACTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011526196.1
CDS	16..1665
Translation	MTQGPGGRAPPAPPAPPEPEAPTTFCALLPRMPQWKFAAPGGFLGRGPAAARAAGASGGADPQPEPAGPGGVPALAAAVLGACEPRCAAPCPLPALSRCRGAGSRGSRGGRGAAGSGDAAAAAEWIRKGSFIHKPAHGWLHPDARVLGPGVSYVVRYMGCIEVLRSMRSLDFNTRTQVTREAINRLHEAVPGVRGSWKKKAPNKALASVLGKSNLRFAGMSISIHISTDGLSLSVPATRQVIANHHMPSISFASGGDTDMTDYVAYVAKDPINQRACHILECCEGLAQSIISTVGQAFELRFKQYLHSPPKVALPPERLAGPEESAWGDEEDSLEHNYYNSIPGKEPPLGGLVDSRLALTQPCALTALDQGPSPSLRDACSLPWDVGSTGTGPFEDALKLHECSVAAGVTAAPLPLEDQWPSPPTRRAPVAPTEEQLRQEPWYHGRMSRRAAERMLRADGDFLVRDSVTNPGQYVLTGMHAGQPKHLLLVDPEGVVSCAQVGGSRGIQGLRWAQVGGSQGSRGSRGMQELSMFMKFFQIVPDVAFDQLL

Target ORF information:

RefSeq Version	XM_011527894.2
Organism	Homo sapiens(human)
Definition	Homo sapiens SHC adaptor protein 2 (SHC2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011527894.2

ORF Insert Sequence:

ATGACGCAGG GTCCGGGCGG GCGCGCGCCC CCGGCGCCCC CCGCGCCCCC CGAGCCCGAG 
GCGCCCACCA CCTTCTGCGC GTTGCTGCCC CGAATGCCGC AGTGGAAGTT CGCGGCCCCG 
GGCGGCTTCC TGGGCCGCGG CCCGGCGGCG GCGCGGGCGG CTGGGGCCTC GGGGGGCGCG 
GACCCCCAAC CCGAGCCGGC GGGCCCGGGG GGCGTCCCGG CGCTGGCGGC CGCCGTCCTG 
GGCGCCTGCG AGCCCCGCTG CGCCGCGCCC TGTCCCCTGC CCGCGCTCAG CCGCTGTCGG 
GGCGCGGGGT CGCGGGGGTC GCGGGGCGGG CGGGGGGCGG CGGGGTCCGG GGACGCCGCC 
GCCGCCGCCG AGTGGATCCG GAAGGGCAGC TTCATCCACA AACCCGCGCA CGGCTGGCTA 
CACCCCGACG CCAGGGTCCT GGGGCCCGGG GTCTCCTACG TCGTGCGGTA CATGGGCTGC 
ATCGAGGTTC TCCGCTCTAT GCGCTCCCTG GACTTTAACA CGCGCACGCA GGTGACCAGG 
GAAGCCATCA ACCGGCTCCA TGAGGCCGTG CCTGGCGTCC GGGGATCCTG GAAGAAAAAG 
GCCCCCAACA AGGCCCTGGC GTCCGTCCTG GGCAAGAGCA ACCTTCGCTT TGCCGGCATG 
AGCATCTCCA TCCACATCTC CACTGATGGC CTCAGCCTCT CCGTGCCTGC CACGCGCCAG 
GTCATCGCCA ACCACCACAT GCCGTCCATC TCCTTCGCGT CAGGCGGAGA CACGGACATG 
ACGGATTACG TGGCCTACGT CGCCAAGGAC CCCATCAACC AGAGAGCCTG CCACATCCTG 
GAGTGCTGTG AGGGCCTGGC ACAGAGCATC ATCAGCACCG TGGGCCAAGC TTTCGAGCTG 
CGCTTCAAGC AGTACCTGCA CAGCCCGCCC AAGGTGGCGC TGCCCCCAGA AAGGCTGGCA 
GGGCCGGAGG AGTCGGCCTG GGGGGACGAG GAGGACTCTT TGGAGCACAA TTACTACAAC 
AGCATCCCGG GGAAGGAGCC GCCGCTGGGC GGGCTAGTGG ACTCCAGGCT GGCCCTGACA 
CAGCCCTGCG CCCTCACGGC CCTCGACCAG GGCCCATCTC CTTCTCTAAG AGATGCCTGC 
AGCCTGCCAT GGGACGTGGG GTCCACCGGT ACAGGACCCT TTGAGGATGC CCTGAAGTTG 
CATGAGTGCT CAGTGGCGGC AGGCGTGACA GCAGCCCCTC TTCCCTTGGA GGACCAGTGG 
CCCAGCCCCC CTACCCGCCG GGCCCCTGTG GCCCCCACGG AGGAACAGCT GCGTCAGGAG 
CCCTGGTACC ACGGCCGGAT GAGCCGCCGG GCGGCAGAGA GGATGCTTCG AGCTGACGGG 
GACTTCCTTG TGCGAGACAG CGTCACCAAC CCCGGGCAGT ATGTCCTCAC CGGCATGCAC 
GCCGGGCAGC CCAAGCACCT GCTGCTCGTG GACCCCGAGG GCGTGGTAAG CTGTGCACAG 
GTGGGAGGGT CTCGGGGCAT CCAGGGGCTT CGCTGGGCAC AGGTGGGAGG GTCTCAAGGG 
TCTCGAGGGT CTCGGGGCAT GCAGGAGCTT TCCATGTTTA TGAAGTTTTT CCAGATTGTT 
CCAGATGTTG CCTTTGACCA GCTACTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SHC2 ( XM_011527895.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011526197.1 Homo sapiens SHC adaptor protein 2 (SHC2), transcript variant X3, mRNA.

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CloneID	OHu66460
Clone ID Related Accession (Same CDS sequence)	XM_011527895.2
Accession Version	XM_011527895.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1614bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	SHC-transforming protein 2 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011527895.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACGCAGG GTCCGGGCGG GCGCGCGCCC CCGGCGCCCC CCGCGCCCCC CGAGCCCGAG 
GCGCCCACCA CCTTCTGCGC GTTGCTGCCC CGAATGCCGC AGTGGAAGTT CGCGGCCCCG 
GGCGGCTTCC TGGGCCGCGG CCCGGCGGCG GCGCGGGCGG CTGGGGCCTC GGGGGGCGCG 
GACCCCCAAC CCGAGCCGGC GGGCCCGGGG GGCGTCCCGG CGCTGGCGGC CGCCGTCCTG 
GGCGCCTGCG AGCCCCGCTG CGCCGCGCCC TGTCCCCTGC CCGCGCTCAG CCGCTGTCGG 
GGCGCGGGGT CGCGGGGGTC GCGGGGCGGG CGGGGGGCGG CGGGGTCCGG GGACGCCGCC 
GCCGCCGCCG AGTGGATCCG GAAGGGCAGC TTCATCCACA AACCCGCGCA CGGCTGGCTA 
CACCCCGACG CCAGGGTCCT GGGGCCCGGG GTCTCCTACG TCGTGCGGTA CATGGGCTGC 
ATCGAGGTTC TCCGCTCTAT GCGCTCCCTG GACTTTAACA CGCGCACGCA GGTGACCAGG 
GAAGCCATCA ACCGGCTCCA TGAGGCCGTG CCTGGCGTCC GGGGATCCTG GAAGAAAAAG 
GCCCCCAACA AGGCCCTGGC GTCCGTCCTG GGCAAGAGCA ACCTTCGCTT TGCCGGCATG 
AGCATCTCCA TCCACATCTC CACTGATGGC CTCAGCCTCT CCGTGCCTGC CACGCGCCAG 
GTCATCGCCA ACCACCACAT GCCGTCCATC TCCTTCGCGT CAGGCGGAGA CACGGACATG 
ACGGATTACG TGGCCTACGT CGCCAAGGAC CCCATCAACC AGAGAGCCTG CCACATCCTG 
GAGTGCTGTG AGGGCCTGGC ACAGAGCATC ATCAGCACCG TGGGCCAAGC TTTCGAGCTG 
CGCTTCAAGC AGTACCTGCA CAGCCCGCCC AAGGTGGCGC TGCCCCCAGA AAGGCTGGCA 
GGGCCGGAGG AGTCGGCCTG GGGGGACGAG GAGGACTCTT TGGAGCACAA TTACTACAAC 
AGCATCCCGG GGAAGGAGCC GCCGCTGGGC GGGCTAGTGG ACTCCAGGCT GGCCCTGACA 
CAGCCCTGCG CCCTCACGGC CCTCGACCAG GGCCCATCTC CTTCTCTAAG AGATGCCTGC 
AGCCTGCCAT GGGACGTGGG GTCCACCGGT ACAGGACCCT TTGAGGATGC CCTGAAGTTG 
CATGAGTGCT CAGTGGCGGC AGGCGTGACA GCAGCCCCTC TTCCCTTGGA GGACCAGTGG 
CCCAGCCCCC CTACCCGCCG GGCCCCTGTG GCCCCCACGG AGGAACAGCT GCGTCAGGAG 
CCCTGGTACC ACGGCCGGAT GAGCCGCCGG GCGGCAGAGA GGATGCTTCG AGCTGACGGG 
GACTTCCTTG TGCGAGACAG CGTCACCAAC CCCGGGCAGT ATGTCCTCAC CGGCATGCAC 
GCCGGGCAGC CCAAGCACCT GCTGCTCGTG GACCCCGAGG GCGTGGTACG GACGAAGGAC 
GTGCTGTTTG AGAGCATCAG CCACCTGATC GACCACCACC TGCAGAACGG GCAGCCCATC 
GTGGCCGCCG AGAGTGAGCT GCACCTGCGT GGCGTGGTCT CACGGGAGCC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011526197.1
CDS	16..1629
Translation	MTQGPGGRAPPAPPAPPEPEAPTTFCALLPRMPQWKFAAPGGFLGRGPAAARAAGASGGADPQPEPAGPGGVPALAAAVLGACEPRCAAPCPLPALSRCRGAGSRGSRGGRGAAGSGDAAAAAEWIRKGSFIHKPAHGWLHPDARVLGPGVSYVVRYMGCIEVLRSMRSLDFNTRTQVTREAINRLHEAVPGVRGSWKKKAPNKALASVLGKSNLRFAGMSISIHISTDGLSLSVPATRQVIANHHMPSISFASGGDTDMTDYVAYVAKDPINQRACHILECCEGLAQSIISTVGQAFELRFKQYLHSPPKVALPPERLAGPEESAWGDEEDSLEHNYYNSIPGKEPPLGGLVDSRLALTQPCALTALDQGPSPSLRDACSLPWDVGSTGTGPFEDALKLHECSVAAGVTAAPLPLEDQWPSPPTRRAPVAPTEEQLRQEPWYHGRMSRRAAERMLRADGDFLVRDSVTNPGQYVLTGMHAGQPKHLLLVDPEGVVRTKDVLFESISHLIDHHLQNGQPIVAAESELHLRGVVSREP

Target ORF information:

RefSeq Version	XM_011527895.2
Organism	Homo sapiens(human)
Definition	Homo sapiens SHC adaptor protein 2 (SHC2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011527895.2

ORF Insert Sequence:

ATGACGCAGG GTCCGGGCGG GCGCGCGCCC CCGGCGCCCC CCGCGCCCCC CGAGCCCGAG 
GCGCCCACCA CCTTCTGCGC GTTGCTGCCC CGAATGCCGC AGTGGAAGTT CGCGGCCCCG 
GGCGGCTTCC TGGGCCGCGG CCCGGCGGCG GCGCGGGCGG CTGGGGCCTC GGGGGGCGCG 
GACCCCCAAC CCGAGCCGGC GGGCCCGGGG GGCGTCCCGG CGCTGGCGGC CGCCGTCCTG 
GGCGCCTGCG AGCCCCGCTG CGCCGCGCCC TGTCCCCTGC CCGCGCTCAG CCGCTGTCGG 
GGCGCGGGGT CGCGGGGGTC GCGGGGCGGG CGGGGGGCGG CGGGGTCCGG GGACGCCGCC 
GCCGCCGCCG AGTGGATCCG GAAGGGCAGC TTCATCCACA AACCCGCGCA CGGCTGGCTA 
CACCCCGACG CCAGGGTCCT GGGGCCCGGG GTCTCCTACG TCGTGCGGTA CATGGGCTGC 
ATCGAGGTTC TCCGCTCTAT GCGCTCCCTG GACTTTAACA CGCGCACGCA GGTGACCAGG 
GAAGCCATCA ACCGGCTCCA TGAGGCCGTG CCTGGCGTCC GGGGATCCTG GAAGAAAAAG 
GCCCCCAACA AGGCCCTGGC GTCCGTCCTG GGCAAGAGCA ACCTTCGCTT TGCCGGCATG 
AGCATCTCCA TCCACATCTC CACTGATGGC CTCAGCCTCT CCGTGCCTGC CACGCGCCAG 
GTCATCGCCA ACCACCACAT GCCGTCCATC TCCTTCGCGT CAGGCGGAGA CACGGACATG 
ACGGATTACG TGGCCTACGT CGCCAAGGAC CCCATCAACC AGAGAGCCTG CCACATCCTG 
GAGTGCTGTG AGGGCCTGGC ACAGAGCATC ATCAGCACCG TGGGCCAAGC TTTCGAGCTG 
CGCTTCAAGC AGTACCTGCA CAGCCCGCCC AAGGTGGCGC TGCCCCCAGA AAGGCTGGCA 
GGGCCGGAGG AGTCGGCCTG GGGGGACGAG GAGGACTCTT TGGAGCACAA TTACTACAAC 
AGCATCCCGG GGAAGGAGCC GCCGCTGGGC GGGCTAGTGG ACTCCAGGCT GGCCCTGACA 
CAGCCCTGCG CCCTCACGGC CCTCGACCAG GGCCCATCTC CTTCTCTAAG AGATGCCTGC 
AGCCTGCCAT GGGACGTGGG GTCCACCGGT ACAGGACCCT TTGAGGATGC CCTGAAGTTG 
CATGAGTGCT CAGTGGCGGC AGGCGTGACA GCAGCCCCTC TTCCCTTGGA GGACCAGTGG 
CCCAGCCCCC CTACCCGCCG GGCCCCTGTG GCCCCCACGG AGGAACAGCT GCGTCAGGAG 
CCCTGGTACC ACGGCCGGAT GAGCCGCCGG GCGGCAGAGA GGATGCTTCG AGCTGACGGG 
GACTTCCTTG TGCGAGACAG CGTCACCAAC CCCGGGCAGT ATGTCCTCAC CGGCATGCAC 
GCCGGGCAGC CCAAGCACCT GCTGCTCGTG GACCCCGAGG GCGTGGTACG GACGAAGGAC 
GTGCTGTTTG AGAGCATCAG CCACCTGATC GACCACCACC TGCAGAACGG GCAGCCCATC 
GTGGCCGCCG AGAGTGAGCT GCACCTGCGT GGCGTGGTCT CACGGGAGCC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

CD95 promotes metastatic spread via Sck in pancreatic ductal adenocarcinoma.
Cell death and differentiation22(7)1192-202(2015 Jul)
Teodorczyk M,Kleber S,Wollny D,Sefrin JP,Aykut B,Mateos A,Herhaus P,Sancho-Martinez I,Hill O,Gieffers C,Sykora J,Weichert W,Eisen C,Trumpp A,Sprick MR,Bergmann F,Welsch T,Martin-Villalba A

Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome.
Molecular & cellular proteomics : MCP13(7)1705-23(2014 Jul)
Leung KK,Hause RJ Jr,Barkinge JL,Ciaccio MF,Chuu CP,Jones RB

SHC2 gene copy number in multiple system atrophy (MSA).
Clinical autonomic research : official journal of the Clinical Autonomic Research Society24(1)25-30(2014 Feb)
Ferguson MC,Garland EM,Hedges L,Womack-Nunley B,Hamid R,Phillips JA 3rd,Shibao CA,Raj SR,Biaggioni I,Robertson D

Copy number loss of (src homology 2 domain containing)-transforming protein 2 (SHC2) gene: discordant loss in monozygotic twins and frequent loss in patients with multiple system atrophy.
Molecular brain424(2011 Jun)
Sasaki H,Emi M,Iijima H,Ito N,Sato H,Yabe I,Kato T,Utsumi J,Matsubara K

Genomic annotation of 15,809 ESTs identified from pooled early gestation human eyes.
Physiological genomics25(1)9-15(2006 Mar)
Choy KW,Wang CC,Ogura A,Lau TK,Rogers MS,Ikeo K,Gojobori T,Lam DS,Pang CP

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SHC2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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