ALOX15B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ALOX15B
Entrez Gene ID	247
Full Name	arachidonate 15-lipoxygenase, type B
Synonyms	15-LOX-2
General protein information	Preferred Names arachidonate 15-lipoxygenase, type B Names arachidonate 15-lipoxygenase B 15-LOX-B 15S-lipoxygenase arachidonate 15-lipoxygenase 2 arachidonate 15-lipoxygenase type II arachidonate 15-lipoxygenase, second type arachidonate omega(6) lipoxygenase linoleate 13-lipoxygenase 15-LOb
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17p13.1
Summary	This gene encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
Disorder MIM:	603697

mRNA and Protein(s)

mRNA	Protein	Name
NM_001039131.2	NP_001034220.1	arachidonate 15-lipoxygenase B isoform b
NM_001039131.1	NP_001034220.1	arachidonate 15-lipoxygenase B isoform b
NM_001141.2	NP_001132.2	arachidonate 15-lipoxygenase B isoform d
NM_001141.3	NP_001132.2	arachidonate 15-lipoxygenase B isoform d
NM_001039130.1	NP_001034219.1	arachidonate 15-lipoxygenase B isoform a

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	ALOX15B	XP_511865.2
Gallus gallus (chicken)	ALOXE3	XP_423676.4
Rattus norvegicus (Norway rat)	Alox15b	NP_695213.1
	ALOX15B	XP_001111890.1
Canis lupus familiaris (dog)	ALOX15B	XP_546603.1
Bos taurus (cattle)	ALOX15B	NP_001192632.1
Mus musculus (house mouse)	Alox8	NP_033791.1
Homo sapiens (human)	ALOX15B	NP_001132.2

Gene Ontology
Bibliography

Related articles in PubMed

Structural Dynamics of 15-Lipoxygenase-2 via Hydrogen-Deuterium Exchange.
Droege KD, Keithly ME, Sanders CR, Armstrong RN, Thompson MK
Biochemistry56(38)5065-5074(2017 09)

Membrane-dependent Activities of Human 15-LOX-2 and Its Murine Counterpart: IMPLICATIONS FOR MURINE MODELS OF ATHEROSCLEROSIS.
Bender G, Schexnaydre EE, Murphy RC, Uhlson C, Newcomer ME
The Journal of biological chemistry291(37)19413-24(2016 09)

Strict Regiospecificity of Human Epithelial 15-Lipoxygenase-2 Delineates Its Transcellular Synthesis Potential.
Green AR, Barbour S, Horn T, Carlos J, Raskatov JA, Holman TR
Biochemistry55(20)2832-40(2016 05)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Ca(2+) binding induces major structural changes in the 15-lipoxygenase-2 PLAT domain.
Title: Structural Dynamics of 15-Lipoxygenase-2 via Hydrogen-Deuterium Exchange.

15-LOX-2 is distributed at the plasma membrane when cells are stimulated by the addition Ca(2+) ionophore and that cellular localization is dependent upon the presence of a putative membrane insertion loop.
Title: Membrane-dependent Activities of Human 15-LOX-2 and Its Murine Counterpart: IMPLICATIONS FOR MURINE MODELS OF ATHEROSCLEROSIS.

these results demonstrate the strict regiospecificity of h15-LOX-2 that circumscribes its role in transcellular synthesis.
Title: Strict Regiospecificity of Human Epithelial 15-Lipoxygenase-2 Delineates Its Transcellular Synthesis Potential.

This study combined molecular dynamics simulations, QM/MM calculations, and umbrella sampling free energy simulations to study the hydrogen atom abstraction from arachidonic acid catalyzed by the human enzyme 15-lipoxygenase-2.
Title: Understanding the Mechanism of the Hydrogen Abstraction from Arachidonic Acid Catalyzed by the Human Enzyme 15-Lipoxygenase-2. A Quantum Mechanics/Molecular Mechanics Free Energy Simulation.

Hpoxia-induced pulmonary vascular remodeling is associated with increased levels of 15-LO-2.
Title: Modulation of Pulmonary Vascular Remodeling in Hypoxia: Role of 15-LOX-2/15-HETE-MAPKs Pathway.

The following ALOX15B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ALOX15B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18842	NM_001141.3 Latest version!	Homo sapiens arachidonate 15-lipoxygenase type B (ALOX15B), transcript variant d, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu30405	NM_001039131.2 Latest version!	Homo sapiens arachidonate 15-lipoxygenase type B (ALOX15B), transcript variant b, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$349.30 $499.00
OHu30473	NM_001039130.1 Latest version!	Homo sapiens arachidonate 15-lipoxygenase type B (ALOX15B), transcript variant a, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$384.30 $549.00
View Old Accession Versions >>
OHu30405	NM_001039131.1	Homo sapiens arachidonate 15-lipoxygenase type B (ALOX15B), transcript variant b, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$349.30 $499.00
OHu18842	NM_001141.2	Homo sapiens arachidonate 15-lipoxygenase, type B (ALOX15B), transcript variant d, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ALOX15B ( NM_001141.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001132.2 Homo sapiens arachidonate 15-lipoxygenase, type B (ALOX15B), transcript variant d, mRNA.

Price & Availability↑

CloneID	OHu18842
Clone ID Related Accession (Same CDS sequence)	NM_001141.2 , NM_001141.3
Accession Version	NM_001141.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2031bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-29
Organism	Homo sapiens(human)
Product	arachidonate 15-lipoxygenase B isoform d
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP327830.1, AF468051.1, CA405703.1, BC063647.1 and CA307212.1. This sequence is a reference standard in the RefSeqGene project. On Jan 18, 2006 this sequence version replaced NM_001141.1. Transcript Variant: This variant (d) represents the longest transcript and encodes the longest isoform (d). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC063647.1, SRR1803613.32624.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGAGT TCAGGGTCAG GGTGTCCACC GGAGAAGCCT TCGGGGCTGG CACATGGGAC 
AAAGTGTCTG TCAGCATCGT GGGGACCCGG GGAGAGAGCC CCCCACTGCC CCTGGACAAT 
CTCGGCAAGG AGTTCACTGC GGGCGCTGAG GAGGACTTCC AGGTGACGCT CCCGGAGGAC 
GTAGGCCGAG TGCTGCTGCT GCGCGTGCAC AAGGCGCCCC CAGTGCTGCC CCTGCTGGGG 
CCCCTGGCCC CGGATGCCTG GTTCTGCCGC TGGTTCCAGC TGACACCGCC GCGGGGCGGC 
CACCTCCTCT TCCCCTGCTA CCAGTGGCTG GAGGGGGCGG GGACCCTGGT GCTGCAGGAG 
GGTACAGCCA AGGTGTCCTG GGCAGACCAC CACCCTGTGC TCCAGCAACA GCGCCAGGAG 
GAGCTTCAGG CCCGGCAGGA GATGTACCAG TGGAAGGCTT ACAACCCAGG TTGGCCTCAC 
TGCCTGGATG AAAAGACAGT GGAAGACTTG GAGCTCAATA TCAAATACTC CACAGCCAAG 
AATGCCAACT TTTATCTACA GGCTGGCTCT GCTTTTGCAG AGATGAAAAT CAAGGGGTTG 
CTGGACCGCA AGGGGCTCTG GAGGAGTCTG AATGAGATGA AAAGGATCTT CAACTTCCGG 
AGGACCCCAG CAGCTGAGCA CGCATTTGAG CACTGGCAGG AGGACGCCTT CTTCGCCTCC 
CAGTTCCTGA ATGGTCTCAA CCCTGTCCTG ATCCGCCGCT GTCACTACCT CCCAAAGAAC 
TTCCCCGTCA CTGATGCCAT GGTGGCCTCA GTGTTGGGTC CTGGGACCAG CTTGCAGGCT 
GAGCTAGAGA AGGGCTCCCT GTTCTTGGTG GATCACGGCA TCCTCTCTGG CATCCAGACC 
AATGTCATTA ATGGGAAGCC TCAGTTCTCT GCGGCCCCAA TGACCCTGCT ATACCAGAGC 
CCAGGCTGCG GGCCGCTGCT GCCTCTCGCC ATCCAGCTCA GCCAGACCCC CGGCCCAAAC 
AGCCCCATCT TCCTGCCCAC TGATGACAAG TGGGACTGGT TGCTGGCCAA GACCTGGGTG 
CGCAATGCCG AGTTCTCCTT CCATGAGGCC CTCACGCACC TGCTGCACTC ACATCTGCTG 
CCTGAGGTCT TCACCCTGGC TACCCTGCGT CAGCTGCCCC ACTGCCACCC TCTCTTCAAG 
CTGCTGATCC CGCACACCCG ATACACCCTG CACATCAACA CACTCGCCCG GGAGCTGCTT 
ATCGTGCCAG GGCAGGTGGT GGACAGGTCC ACAGGCATCG GCATTGAAGG CTTCTCTGAG 
TTGATACAGA GGAACATGAA GCAGCTGAAC TATTCTCTCC TGTGTCTGCC TGAGGATATC 
CGGACCCGAG GAGTTGAAGA CATCCCAGGC TACTACTACC GTGATGATGG GATGCAGATC 
TGGGGTGCAG TGGAACGCTT TGTCTCTGAA ATCATCGGTA TCTACTACCC AAGTGATGAG 
TCTGTCCAAG ATGACAGAGA GCTCCAGGCC TGGGTCAGAG AGATCTTCTC CAAGGGCTTC 
CTAAACCAGG AGAGCTCAGG TATACCCTCC TCACTGGAGA CCCGGGAAGC CCTGGTGCAG 
TATGTCACCA TGGTGATATT CACCTGCTCC GCCAAGCATG CGGCTGTCAG TGCAGGGCAG 
TTTGACTCCT GTGCTTGGAT GCCCAACCTG CCACCCAGCA TGCAGCTGCC ACCACCCACC 
TCCAAAGGCC TGGCAACATG CGAGGGCTTC ATAGCCACCC TCCCACCTGT CAATGCCACA 
TGTGATGTCA TCCTTGCTCT CTGGTTGCTG AGCAAGGAGC CTGGAGACCA AAGGCCCCTG 
GGCACCTATC CGGATGAGCA CTTCACAGAG GAGGCCCCTC GGCGGAGCAT CGCCACCTTC 
CAGAGCCGCC TGGCCCAGAT CTCGAGGGGC ATCCAGGAGC GGAACCAGGG CCTGGTGCTG 
CCCTACACCT ACCTAGACCC TCCCCTCATC GAGAACAGCG TCTCCATCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001132.2
CDS	117..2147
Translation	MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPEDVGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQEGTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAKNANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFASQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQTNVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELLIVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQIWGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNATCDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVLPYTYLDPPLIENSVSI

Target ORF information:

RefSeq Version	NM_001141.2
Organism	Homo sapiens(human)
Definition	Homo sapiens arachidonate 15-lipoxygenase, type B (ALOX15B), transcript variant d, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001141.2

ORF Insert Sequence:

ATGGCCGAGT TCAGGGTCAG GGTGTCCACC GGAGAAGCCT TCGGGGCTGG CACATGGGAC 
AAAGTGTCTG TCAGCATCGT GGGGACCCGG GGAGAGAGCC CCCCACTGCC CCTGGACAAT 
CTCGGCAAGG AGTTCACTGC GGGCGCTGAG GAGGACTTCC AGGTGACGCT CCCGGAGGAC 
GTAGGCCGAG TGCTGCTGCT GCGCGTGCAC AAGGCGCCCC CAGTGCTGCC CCTGCTGGGG 
CCCCTGGCCC CGGATGCCTG GTTCTGCCGC TGGTTCCAGC TGACACCGCC GCGGGGCGGC 
CACCTCCTCT TCCCCTGCTA CCAGTGGCTG GAGGGGGCGG GGACCCTGGT GCTGCAGGAG 
GGTACAGCCA AGGTGTCCTG GGCAGACCAC CACCCTGTGC TCCAGCAACA GCGCCAGGAG 
GAGCTTCAGG CCCGGCAGGA GATGTACCAG TGGAAGGCTT ACAACCCAGG TTGGCCTCAC 
TGCCTGGATG AAAAGACAGT GGAAGACTTG GAGCTCAATA TCAAATACTC CACAGCCAAG 
AATGCCAACT TTTATCTACA GGCTGGCTCT GCTTTTGCAG AGATGAAAAT CAAGGGGTTG 
CTGGACCGCA AGGGGCTCTG GAGGAGTCTG AATGAGATGA AAAGGATCTT CAACTTCCGG 
AGGACCCCAG CAGCTGAGCA CGCATTTGAG CACTGGCAGG AGGACGCCTT CTTCGCCTCC 
CAGTTCCTGA ATGGTCTCAA CCCTGTCCTG ATCCGCCGCT GTCACTACCT CCCAAAGAAC 
TTCCCCGTCA CTGATGCCAT GGTGGCCTCA GTGTTGGGTC CTGGGACCAG CTTGCAGGCT 
GAGCTAGAGA AGGGCTCCCT GTTCTTGGTG GATCACGGCA TCCTCTCTGG CATCCAGACC 
AATGTCATTA ATGGGAAGCC TCAGTTCTCT GCGGCCCCAA TGACCCTGCT ATACCAGAGC 
CCAGGCTGCG GGCCGCTGCT GCCTCTCGCC ATCCAGCTCA GCCAGACCCC CGGCCCAAAC 
AGCCCCATCT TCCTGCCCAC TGATGACAAG TGGGACTGGT TGCTGGCCAA GACCTGGGTG 
CGCAATGCCG AGTTCTCCTT CCATGAGGCC CTCACGCACC TGCTGCACTC ACATCTGCTG 
CCTGAGGTCT TCACCCTGGC TACCCTGCGT CAGCTGCCCC ACTGCCACCC TCTCTTCAAG 
CTGCTGATCC CGCACACCCG ATACACCCTG CACATCAACA CACTCGCCCG GGAGCTGCTT 
ATCGTGCCAG GGCAGGTGGT GGACAGGTCC ACAGGCATCG GCATTGAAGG CTTCTCTGAG 
TTGATACAGA GGAACATGAA GCAGCTGAAC TATTCTCTCC TGTGTCTGCC TGAGGATATC 
CGGACCCGAG GAGTTGAAGA CATCCCAGGC TACTACTACC GTGATGATGG GATGCAGATC 
TGGGGTGCAG TGGAACGCTT TGTCTCTGAA ATCATCGGTA TCTACTACCC AAGTGATGAG 
TCTGTCCAAG ATGACAGAGA GCTCCAGGCC TGGGTCAGAG AGATCTTCTC CAAGGGCTTC 
CTAAACCAGG AGAGCTCAGG TATACCCTCC TCACTGGAGA CCCGGGAAGC CCTGGTGCAG 
TATGTCACCA TGGTGATATT CACCTGCTCC GCCAAGCATG CGGCTGTCAG TGCAGGGCAG 
TTTGACTCCT GTGCTTGGAT GCCCAACCTG CCACCCAGCA TGCAGCTGCC ACCACCCACC 
TCCAAAGGCC TGGCAACATG CGAGGGCTTC ATAGCCACCC TCCCACCTGT CAATGCCACA 
TGTGATGTCA TCCTTGCTCT CTGGTTGCTG AGCAAGGAGC CTGGAGACCA AAGGCCCCTG 
GGCACCTATC CGGATGAGCA CTTCACAGAG GAGGCCCCTC GGCGGAGCAT CGCCACCTTC 
CAGAGCCGCC TGGCCCAGAT CTCGAGGGGC ATCCAGGAGC GGAACCAGGG CCTGGTGCTG 
CCCTACACCT ACCTAGACCC TCCCCTCATC GAGAACAGCG TCTCCATCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ALOX15B ( NM_001141.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001132.2 Homo sapiens arachidonate 15-lipoxygenase type B (ALOX15B), transcript variant d, mRNA.

Price & Availability↑

CloneID	OHu18842
Clone ID Related Accession (Same CDS sequence)	NM_001141.2 , NM_001141.3
Accession Version	NM_001141.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2031bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-07
Organism	Homo sapiens(human)
Product	arachidonate 15-lipoxygenase B isoform d
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP327830.1, AF468051.1, CA405703.1, BC063647.1 and CA307212.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_001141.2. Transcript Variant: This variant (d) represents the longest transcript and encodes the longest isoform (d). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC063647.1, SRR1803613.32624.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000380183.9/ ENSP00000369530.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCGAGT TCAGGGTCAG GGTGTCCACC GGAGAAGCCT TCGGGGCTGG CACATGGGAC 
AAAGTGTCTG TCAGCATCGT GGGGACCCGG GGAGAGAGCC CCCCACTGCC CCTGGACAAT 
CTCGGCAAGG AGTTCACTGC GGGCGCTGAG GAGGACTTCC AGGTGACGCT CCCGGAGGAC 
GTAGGCCGAG TGCTGCTGCT GCGCGTGCAC AAGGCGCCCC CAGTGCTGCC CCTGCTGGGG 
CCCCTGGCCC CGGATGCCTG GTTCTGCCGC TGGTTCCAGC TGACACCGCC GCGGGGCGGC 
CACCTCCTCT TCCCCTGCTA CCAGTGGCTG GAGGGGGCGG GGACCCTGGT GCTGCAGGAG 
GGTACAGCCA AGGTGTCCTG GGCAGACCAC CACCCTGTGC TCCAGCAACA GCGCCAGGAG 
GAGCTTCAGG CCCGGCAGGA GATGTACCAG TGGAAGGCTT ACAACCCAGG TTGGCCTCAC 
TGCCTGGATG AAAAGACAGT GGAAGACTTG GAGCTCAATA TCAAATACTC CACAGCCAAG 
AATGCCAACT TTTATCTACA GGCTGGCTCT GCTTTTGCAG AGATGAAAAT CAAGGGGTTG 
CTGGACCGCA AGGGGCTCTG GAGGAGTCTG AATGAGATGA AAAGGATCTT CAACTTCCGG 
AGGACCCCAG CAGCTGAGCA CGCATTTGAG CACTGGCAGG AGGACGCCTT CTTCGCCTCC 
CAGTTCCTGA ATGGTCTCAA CCCTGTCCTG ATCCGCCGCT GTCACTACCT CCCAAAGAAC 
TTCCCCGTCA CTGATGCCAT GGTGGCCTCA GTGTTGGGTC CTGGGACCAG CTTGCAGGCT 
GAGCTAGAGA AGGGCTCCCT GTTCTTGGTG GATCACGGCA TCCTCTCTGG CATCCAGACC 
AATGTCATTA ATGGGAAGCC TCAGTTCTCT GCGGCCCCAA TGACCCTGCT ATACCAGAGC 
CCAGGCTGCG GGCCGCTGCT GCCTCTCGCC ATCCAGCTCA GCCAGACCCC CGGCCCAAAC 
AGCCCCATCT TCCTGCCCAC TGATGACAAG TGGGACTGGT TGCTGGCCAA GACCTGGGTG 
CGCAATGCCG AGTTCTCCTT CCATGAGGCC CTCACGCACC TGCTGCACTC ACATCTGCTG 
CCTGAGGTCT TCACCCTGGC TACCCTGCGT CAGCTGCCCC ACTGCCACCC TCTCTTCAAG 
CTGCTGATCC CGCACACCCG ATACACCCTG CACATCAACA CACTCGCCCG GGAGCTGCTT 
ATCGTGCCAG GGCAGGTGGT GGACAGGTCC ACAGGCATCG GCATTGAAGG CTTCTCTGAG 
TTGATACAGA GGAACATGAA GCAGCTGAAC TATTCTCTCC TGTGTCTGCC TGAGGATATC 
CGGACCCGAG GAGTTGAAGA CATCCCAGGC TACTACTACC GTGATGATGG GATGCAGATC 
TGGGGTGCAG TGGAACGCTT TGTCTCTGAA ATCATCGGTA TCTACTACCC AAGTGATGAG 
TCTGTCCAAG ATGACAGAGA GCTCCAGGCC TGGGTCAGAG AGATCTTCTC CAAGGGCTTC 
CTAAACCAGG AGAGCTCAGG TATACCCTCC TCACTGGAGA CCCGGGAAGC CCTGGTGCAG 
TATGTCACCA TGGTGATATT CACCTGCTCC GCCAAGCATG CGGCTGTCAG TGCAGGGCAG 
TTTGACTCCT GTGCTTGGAT GCCCAACCTG CCACCCAGCA TGCAGCTGCC ACCACCCACC 
TCCAAAGGCC TGGCAACATG CGAGGGCTTC ATAGCCACCC TCCCACCTGT CAATGCCACA 
TGTGATGTCA TCCTTGCTCT CTGGTTGCTG AGCAAGGAGC CTGGAGACCA AAGGCCCCTG 
GGCACCTATC CGGATGAGCA CTTCACAGAG GAGGCCCCTC GGCGGAGCAT CGCCACCTTC 
CAGAGCCGCC TGGCCCAGAT CTCGAGGGGC ATCCAGGAGC GGAACCAGGG CCTGGTGCTG 
CCCTACACCT ACCTAGACCC TCCCCTCATC GAGAACAGCG TCTCCATCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001132.2
CDS	98..2128
Translation	MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPEDVGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQEGTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAKNANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFASQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQTNVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELLIVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQIWGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNATCDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVLPYTYLDPPLIENSVSI

Target ORF information:

RefSeq Version	NM_001141.3
Organism	Homo sapiens(human)
Definition	Homo sapiens arachidonate 15-lipoxygenase type B (ALOX15B), transcript variant d, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001141.3

ORF Insert Sequence:

ATGGCCGAGT TCAGGGTCAG GGTGTCCACC GGAGAAGCCT TCGGGGCTGG CACATGGGAC 
AAAGTGTCTG TCAGCATCGT GGGGACCCGG GGAGAGAGCC CCCCACTGCC CCTGGACAAT 
CTCGGCAAGG AGTTCACTGC GGGCGCTGAG GAGGACTTCC AGGTGACGCT CCCGGAGGAC 
GTAGGCCGAG TGCTGCTGCT GCGCGTGCAC AAGGCGCCCC CAGTGCTGCC CCTGCTGGGG 
CCCCTGGCCC CGGATGCCTG GTTCTGCCGC TGGTTCCAGC TGACACCGCC GCGGGGCGGC 
CACCTCCTCT TCCCCTGCTA CCAGTGGCTG GAGGGGGCGG GGACCCTGGT GCTGCAGGAG 
GGTACAGCCA AGGTGTCCTG GGCAGACCAC CACCCTGTGC TCCAGCAACA GCGCCAGGAG 
GAGCTTCAGG CCCGGCAGGA GATGTACCAG TGGAAGGCTT ACAACCCAGG TTGGCCTCAC 
TGCCTGGATG AAAAGACAGT GGAAGACTTG GAGCTCAATA TCAAATACTC CACAGCCAAG 
AATGCCAACT TTTATCTACA GGCTGGCTCT GCTTTTGCAG AGATGAAAAT CAAGGGGTTG 
CTGGACCGCA AGGGGCTCTG GAGGAGTCTG AATGAGATGA AAAGGATCTT CAACTTCCGG 
AGGACCCCAG CAGCTGAGCA CGCATTTGAG CACTGGCAGG AGGACGCCTT CTTCGCCTCC 
CAGTTCCTGA ATGGTCTCAA CCCTGTCCTG ATCCGCCGCT GTCACTACCT CCCAAAGAAC 
TTCCCCGTCA CTGATGCCAT GGTGGCCTCA GTGTTGGGTC CTGGGACCAG CTTGCAGGCT 
GAGCTAGAGA AGGGCTCCCT GTTCTTGGTG GATCACGGCA TCCTCTCTGG CATCCAGACC 
AATGTCATTA ATGGGAAGCC TCAGTTCTCT GCGGCCCCAA TGACCCTGCT ATACCAGAGC 
CCAGGCTGCG GGCCGCTGCT GCCTCTCGCC ATCCAGCTCA GCCAGACCCC CGGCCCAAAC 
AGCCCCATCT TCCTGCCCAC TGATGACAAG TGGGACTGGT TGCTGGCCAA GACCTGGGTG 
CGCAATGCCG AGTTCTCCTT CCATGAGGCC CTCACGCACC TGCTGCACTC ACATCTGCTG 
CCTGAGGTCT TCACCCTGGC TACCCTGCGT CAGCTGCCCC ACTGCCACCC TCTCTTCAAG 
CTGCTGATCC CGCACACCCG ATACACCCTG CACATCAACA CACTCGCCCG GGAGCTGCTT 
ATCGTGCCAG GGCAGGTGGT GGACAGGTCC ACAGGCATCG GCATTGAAGG CTTCTCTGAG 
TTGATACAGA GGAACATGAA GCAGCTGAAC TATTCTCTCC TGTGTCTGCC TGAGGATATC 
CGGACCCGAG GAGTTGAAGA CATCCCAGGC TACTACTACC GTGATGATGG GATGCAGATC 
TGGGGTGCAG TGGAACGCTT TGTCTCTGAA ATCATCGGTA TCTACTACCC AAGTGATGAG 
TCTGTCCAAG ATGACAGAGA GCTCCAGGCC TGGGTCAGAG AGATCTTCTC CAAGGGCTTC 
CTAAACCAGG AGAGCTCAGG TATACCCTCC TCACTGGAGA CCCGGGAAGC CCTGGTGCAG 
TATGTCACCA TGGTGATATT CACCTGCTCC GCCAAGCATG CGGCTGTCAG TGCAGGGCAG 
TTTGACTCCT GTGCTTGGAT GCCCAACCTG CCACCCAGCA TGCAGCTGCC ACCACCCACC 
TCCAAAGGCC TGGCAACATG CGAGGGCTTC ATAGCCACCC TCCCACCTGT CAATGCCACA 
TGTGATGTCA TCCTTGCTCT CTGGTTGCTG AGCAAGGAGC CTGGAGACCA AAGGCCCCTG 
GGCACCTATC CGGATGAGCA CTTCACAGAG GAGGCCCCTC GGCGGAGCAT CGCCACCTTC 
CAGAGCCGCC TGGCCCAGAT CTCGAGGGGC ATCCAGGAGC GGAACCAGGG CCTGGTGCTG 
CCCTACACCT ACCTAGACCC TCCCCTCATC GAGAACAGCG TCTCCATCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ALOX15B ( NM_001039131.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001034220.1 Homo sapiens arachidonate 15-lipoxygenase type B (ALOX15B), transcript variant b, mRNA.

Price & Availability↑

CloneID	OHu30405
Clone ID Related Accession (Same CDS sequence)	NM_001039131.2 , NM_001039131.1
Accession Version	NM_001039131.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1809bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-07
Organism	Homo sapiens(human)
Product	arachidonate 15-lipoxygenase B isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP327830.1, AF468053.1, CA405703.1, CA307212.1 and BC063647.1. On May 31, 2019 this sequence version replaced NM_001039131.1. Transcript Variant: This variant (b) has multiple differences in the coding region but maintains the reading frame, compared to variant d. The encoded isoform (b) is shorter than isoform d. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF468053.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA2142363 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGAGT TCAGGGTCAG GGTGTCCACC GGAGAAGCCT TCGGGGCTGG CACATGGGAC 
AAAGTGTCTG TCAGCATCGT GGGGACCCGG GGAGAGAGCC CCCCACTGCC CCTGGACAAT 
CTCGGCAAGG AGTTCACTGC GGGCGCTGAG GAGGACTTCC AGGTGACGCT CCCGGAGGAC 
GTAGGCCGAG TGCTGCTGCT GCGCGTGCAC AAGGCGCCCC CAGTGCTGCC CCTGCTGGGG 
CCCCTGGCCC CGGATGCCTG GTTCTGCCGC TGGTTCCAGC TGACACCGCC GCGGGGCGGC 
CACCTCCTCT TCCCCTGCTA CCAGTGGCTG GAGGGGGCGG GGACCCTGGT GCTGCAGGAG 
GGTACAGCCA AGGTGTCCTG GGCAGACCAC CACCCTGTGC TCCAGCAACA GCGCCAGGAG 
GAGCTTCAGG CCCGGCAGGA GATGTACCAG TGGAAGGCTT ACAACCCAGG TTGGCCTCAC 
TGCCTGGATG AAAAGACAGT GGAAGACTTG GAGCTCAATA TCAAATACTC CACAGCCAAG 
AATGCCAACT TTTATCTACA GGCTGGCTCT GCTTTTGCAG AGATGAAAAT CAAGGGGTTG 
CTGGACCGCA AGGGGCTCTG GAGGAGTCTG AATGAGATGA AAAGGATCTT CAACTTCCGG 
AGGACCCCAG CAGCTGAGCA CGCATTTGAG CACTGGCAGG AGGACGCCTT CTTCGCCTCC 
CAGTTCCTGA ATGGTCTCAA CCCTGTCCTG ATCCGCCGCT GTCACTACCT CCCAAAGAAC 
TTCCCCGTCA CTGATGCCAT GGTGGCCTCA GTGTTGGGTC CTGGGACCAG CTTGCAGGCT 
GAGCTAGAGA AGGGCTCCCT GTTCTTGGTG GATCACGGCA TCCTCTCTGG CATCCAGACC 
AATGTCATTA ATGGGAAGCC TCAGTTCTCT GCGGCCCCAA TGACCCTGCT ATACCAGAGC 
CCAGGCTGCG GGCCGCTGCT GCCTCTCGCC ATCCAGCTCA GCCAGACCCC CGGCCCAAAC 
AGCCCCATCT TCCTGCCCAC TGATGACAAG TGGGACTGGT TGCTGGCCAA GACCTGGGTG 
CGCAATGCCG AGTTCTCCTT CCATGAGGCC CTCACGCACC TGCTGCACTC ACATCTGCTG 
CCTGAGGTCT TCACCCTGGC TACCCTGCGT CAGCTGCCCC ACTGCCACCC TCTCTTCAAG 
TCCACAGGCA TCGGCATTGA AGGCTTCTCT GAGTTGATAC AGAGGAACAT GAAGCAGCTG 
AACTATTCTC TCCTGTGTCT GCCTGAGGAT ATCCGGACCC GAGGAGTTGA AGACATCCCA 
GGCTACTACT ACCGTGATGA TGGGATGCAG ATCTGGGGTA TACCCTCCTC ACTGGAGACC 
CGGGAAGCCC TGGTGCAGTA TGTCACCATG GTGATATTCA CCTGCTCCGC CAAGCATGCG 
GCTGTCAGTG CAGGGCAGTT TGACTCCTGT GCTTGGATGC CCAACCTGCC ACCCAGCATG 
CAGCTGCCAC CACCCACCTC CAAAGGCCTG GCAACATGCG AGGGCTTCAT AGCCACCCTC 
CCACCTGTCA ATGCCACATG TGATGTCATC CTTGCTCTCT GGTTGCTGAG CAAGGAGCCT 
GGAGACCAAA GGCCCCTGGG CACCTATCCG GATGAGCACT TCACAGAGGA GGCCCCTCGG 
CGGAGCATCG CCACCTTCCA GAGCCGCCTG GCCCAGATCT CGAGGGGCAT CCAGGAGCGG 
AACCAGGGCC TGGTGCTGCC CTACACCTAC CTAGACCCTC CCCTCATCGA GAACAGCGTC 
TCCATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001034220.1
CDS	98..1906
Translation	MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPEDVGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQEGTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAKNANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFASQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQTNVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQIWGIPSSLETREALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNATCDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVLPYTYLDPPLIENSVSI

Target ORF information:

RefSeq Version	NM_001039131.2
Organism	Homo sapiens(human)
Definition	Homo sapiens arachidonate 15-lipoxygenase type B (ALOX15B), transcript variant b, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001039131.2

ORF Insert Sequence:

ATGGCCGAGT TCAGGGTCAG GGTGTCCACC GGAGAAGCCT TCGGGGCTGG CACATGGGAC 
AAAGTGTCTG TCAGCATCGT GGGGACCCGG GGAGAGAGCC CCCCACTGCC CCTGGACAAT 
CTCGGCAAGG AGTTCACTGC GGGCGCTGAG GAGGACTTCC AGGTGACGCT CCCGGAGGAC 
GTAGGCCGAG TGCTGCTGCT GCGCGTGCAC AAGGCGCCCC CAGTGCTGCC CCTGCTGGGG 
CCCCTGGCCC CGGATGCCTG GTTCTGCCGC TGGTTCCAGC TGACACCGCC GCGGGGCGGC 
CACCTCCTCT TCCCCTGCTA CCAGTGGCTG GAGGGGGCGG GGACCCTGGT GCTGCAGGAG 
GGTACAGCCA AGGTGTCCTG GGCAGACCAC CACCCTGTGC TCCAGCAACA GCGCCAGGAG 
GAGCTTCAGG CCCGGCAGGA GATGTACCAG TGGAAGGCTT ACAACCCAGG TTGGCCTCAC 
TGCCTGGATG AAAAGACAGT GGAAGACTTG GAGCTCAATA TCAAATACTC CACAGCCAAG 
AATGCCAACT TTTATCTACA GGCTGGCTCT GCTTTTGCAG AGATGAAAAT CAAGGGGTTG 
CTGGACCGCA AGGGGCTCTG GAGGAGTCTG AATGAGATGA AAAGGATCTT CAACTTCCGG 
AGGACCCCAG CAGCTGAGCA CGCATTTGAG CACTGGCAGG AGGACGCCTT CTTCGCCTCC 
CAGTTCCTGA ATGGTCTCAA CCCTGTCCTG ATCCGCCGCT GTCACTACCT CCCAAAGAAC 
TTCCCCGTCA CTGATGCCAT GGTGGCCTCA GTGTTGGGTC CTGGGACCAG CTTGCAGGCT 
GAGCTAGAGA AGGGCTCCCT GTTCTTGGTG GATCACGGCA TCCTCTCTGG CATCCAGACC 
AATGTCATTA ATGGGAAGCC TCAGTTCTCT GCGGCCCCAA TGACCCTGCT ATACCAGAGC 
CCAGGCTGCG GGCCGCTGCT GCCTCTCGCC ATCCAGCTCA GCCAGACCCC CGGCCCAAAC 
AGCCCCATCT TCCTGCCCAC TGATGACAAG TGGGACTGGT TGCTGGCCAA GACCTGGGTG 
CGCAATGCCG AGTTCTCCTT CCATGAGGCC CTCACGCACC TGCTGCACTC ACATCTGCTG 
CCTGAGGTCT TCACCCTGGC TACCCTGCGT CAGCTGCCCC ACTGCCACCC TCTCTTCAAG 
TCCACAGGCA TCGGCATTGA AGGCTTCTCT GAGTTGATAC AGAGGAACAT GAAGCAGCTG 
AACTATTCTC TCCTGTGTCT GCCTGAGGAT ATCCGGACCC GAGGAGTTGA AGACATCCCA 
GGCTACTACT ACCGTGATGA TGGGATGCAG ATCTGGGGTA TACCCTCCTC ACTGGAGACC 
CGGGAAGCCC TGGTGCAGTA TGTCACCATG GTGATATTCA CCTGCTCCGC CAAGCATGCG 
GCTGTCAGTG CAGGGCAGTT TGACTCCTGT GCTTGGATGC CCAACCTGCC ACCCAGCATG 
CAGCTGCCAC CACCCACCTC CAAAGGCCTG GCAACATGCG AGGGCTTCAT AGCCACCCTC 
CCACCTGTCA ATGCCACATG TGATGTCATC CTTGCTCTCT GGTTGCTGAG CAAGGAGCCT 
GGAGACCAAA GGCCCCTGGG CACCTATCCG GATGAGCACT TCACAGAGGA GGCCCCTCGG 
CGGAGCATCG CCACCTTCCA GAGCCGCCTG GCCCAGATCT CGAGGGGCAT CCAGGAGCGG 
AACCAGGGCC TGGTGCTGCC CTACACCTAC CTAGACCCTC CCCTCATCGA GAACAGCGTC 
TCCATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ALOX15B ( NM_001039131.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001034220.1 Homo sapiens arachidonate 15-lipoxygenase type B (ALOX15B), transcript variant b, mRNA.

Price & Availability↑

CloneID	OHu30405
Clone ID Related Accession (Same CDS sequence)	NM_001039131.2 , NM_001039131.1
Accession Version	NM_001039131.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1809bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-09
Organism	Homo sapiens(human)
Product	arachidonate 15-lipoxygenase B isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP327830.1, AF468053.1, CA405703.1, CA307212.1 and BC063647.1. Transcript Variant: This variant (b) has multiple differences in the coding region but maintains the reading frame, compared to variant d. The encoded isoform (b) is shorter than isoform d. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF468053.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA2142363 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGAGT TCAGGGTCAG GGTGTCCACC GGAGAAGCCT TCGGGGCTGG CACATGGGAC 
AAAGTGTCTG TCAGCATCGT GGGGACCCGG GGAGAGAGCC CCCCACTGCC CCTGGACAAT 
CTCGGCAAGG AGTTCACTGC GGGCGCTGAG GAGGACTTCC AGGTGACGCT CCCGGAGGAC 
GTAGGCCGAG TGCTGCTGCT GCGCGTGCAC AAGGCGCCCC CAGTGCTGCC CCTGCTGGGG 
CCCCTGGCCC CGGATGCCTG GTTCTGCCGC TGGTTCCAGC TGACACCGCC GCGGGGCGGC 
CACCTCCTCT TCCCCTGCTA CCAGTGGCTG GAGGGGGCGG GGACCCTGGT GCTGCAGGAG 
GGTACAGCCA AGGTGTCCTG GGCAGACCAC CACCCTGTGC TCCAGCAACA GCGCCAGGAG 
GAGCTTCAGG CCCGGCAGGA GATGTACCAG TGGAAGGCTT ACAACCCAGG TTGGCCTCAC 
TGCCTGGATG AAAAGACAGT GGAAGACTTG GAGCTCAATA TCAAATACTC CACAGCCAAG 
AATGCCAACT TTTATCTACA GGCTGGCTCT GCTTTTGCAG AGATGAAAAT CAAGGGGTTG 
CTGGACCGCA AGGGGCTCTG GAGGAGTCTG AATGAGATGA AAAGGATCTT CAACTTCCGG 
AGGACCCCAG CAGCTGAGCA CGCATTTGAG CACTGGCAGG AGGACGCCTT CTTCGCCTCC 
CAGTTCCTGA ATGGTCTCAA CCCTGTCCTG ATCCGCCGCT GTCACTACCT CCCAAAGAAC 
TTCCCCGTCA CTGATGCCAT GGTGGCCTCA GTGTTGGGTC CTGGGACCAG CTTGCAGGCT 
GAGCTAGAGA AGGGCTCCCT GTTCTTGGTG GATCACGGCA TCCTCTCTGG CATCCAGACC 
AATGTCATTA ATGGGAAGCC TCAGTTCTCT GCGGCCCCAA TGACCCTGCT ATACCAGAGC 
CCAGGCTGCG GGCCGCTGCT GCCTCTCGCC ATCCAGCTCA GCCAGACCCC CGGCCCAAAC 
AGCCCCATCT TCCTGCCCAC TGATGACAAG TGGGACTGGT TGCTGGCCAA GACCTGGGTG 
CGCAATGCCG AGTTCTCCTT CCATGAGGCC CTCACGCACC TGCTGCACTC ACATCTGCTG 
CCTGAGGTCT TCACCCTGGC TACCCTGCGT CAGCTGCCCC ACTGCCACCC TCTCTTCAAG 
TCCACAGGCA TCGGCATTGA AGGCTTCTCT GAGTTGATAC AGAGGAACAT GAAGCAGCTG 
AACTATTCTC TCCTGTGTCT GCCTGAGGAT ATCCGGACCC GAGGAGTTGA AGACATCCCA 
GGCTACTACT ACCGTGATGA TGGGATGCAG ATCTGGGGTA TACCCTCCTC ACTGGAGACC 
CGGGAAGCCC TGGTGCAGTA TGTCACCATG GTGATATTCA CCTGCTCCGC CAAGCATGCG 
GCTGTCAGTG CAGGGCAGTT TGACTCCTGT GCTTGGATGC CCAACCTGCC ACCCAGCATG 
CAGCTGCCAC CACCCACCTC CAAAGGCCTG GCAACATGCG AGGGCTTCAT AGCCACCCTC 
CCACCTGTCA ATGCCACATG TGATGTCATC CTTGCTCTCT GGTTGCTGAG CAAGGAGCCT 
GGAGACCAAA GGCCCCTGGG CACCTATCCG GATGAGCACT TCACAGAGGA GGCCCCTCGG 
CGGAGCATCG CCACCTTCCA GAGCCGCCTG GCCCAGATCT CGAGGGGCAT CCAGGAGCGG 
AACCAGGGCC TGGTGCTGCC CTACACCTAC CTAGACCCTC CCCTCATCGA GAACAGCGTC 
TCCATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001034220.1
CDS	117..1925
Translation	MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPEDVGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQEGTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAKNANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFASQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQTNVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQIWGIPSSLETREALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNATCDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVLPYTYLDPPLIENSVSI

Target ORF information:

RefSeq Version	NM_001039131.1
Organism	Homo sapiens(human)
Definition	Homo sapiens arachidonate 15-lipoxygenase type B (ALOX15B), transcript variant b, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001039131.1

ORF Insert Sequence:

ATGGCCGAGT TCAGGGTCAG GGTGTCCACC GGAGAAGCCT TCGGGGCTGG CACATGGGAC 
AAAGTGTCTG TCAGCATCGT GGGGACCCGG GGAGAGAGCC CCCCACTGCC CCTGGACAAT 
CTCGGCAAGG AGTTCACTGC GGGCGCTGAG GAGGACTTCC AGGTGACGCT CCCGGAGGAC 
GTAGGCCGAG TGCTGCTGCT GCGCGTGCAC AAGGCGCCCC CAGTGCTGCC CCTGCTGGGG 
CCCCTGGCCC CGGATGCCTG GTTCTGCCGC TGGTTCCAGC TGACACCGCC GCGGGGCGGC 
CACCTCCTCT TCCCCTGCTA CCAGTGGCTG GAGGGGGCGG GGACCCTGGT GCTGCAGGAG 
GGTACAGCCA AGGTGTCCTG GGCAGACCAC CACCCTGTGC TCCAGCAACA GCGCCAGGAG 
GAGCTTCAGG CCCGGCAGGA GATGTACCAG TGGAAGGCTT ACAACCCAGG TTGGCCTCAC 
TGCCTGGATG AAAAGACAGT GGAAGACTTG GAGCTCAATA TCAAATACTC CACAGCCAAG 
AATGCCAACT TTTATCTACA GGCTGGCTCT GCTTTTGCAG AGATGAAAAT CAAGGGGTTG 
CTGGACCGCA AGGGGCTCTG GAGGAGTCTG AATGAGATGA AAAGGATCTT CAACTTCCGG 
AGGACCCCAG CAGCTGAGCA CGCATTTGAG CACTGGCAGG AGGACGCCTT CTTCGCCTCC 
CAGTTCCTGA ATGGTCTCAA CCCTGTCCTG ATCCGCCGCT GTCACTACCT CCCAAAGAAC 
TTCCCCGTCA CTGATGCCAT GGTGGCCTCA GTGTTGGGTC CTGGGACCAG CTTGCAGGCT 
GAGCTAGAGA AGGGCTCCCT GTTCTTGGTG GATCACGGCA TCCTCTCTGG CATCCAGACC 
AATGTCATTA ATGGGAAGCC TCAGTTCTCT GCGGCCCCAA TGACCCTGCT ATACCAGAGC 
CCAGGCTGCG GGCCGCTGCT GCCTCTCGCC ATCCAGCTCA GCCAGACCCC CGGCCCAAAC 
AGCCCCATCT TCCTGCCCAC TGATGACAAG TGGGACTGGT TGCTGGCCAA GACCTGGGTG 
CGCAATGCCG AGTTCTCCTT CCATGAGGCC CTCACGCACC TGCTGCACTC ACATCTGCTG 
CCTGAGGTCT TCACCCTGGC TACCCTGCGT CAGCTGCCCC ACTGCCACCC TCTCTTCAAG 
TCCACAGGCA TCGGCATTGA AGGCTTCTCT GAGTTGATAC AGAGGAACAT GAAGCAGCTG 
AACTATTCTC TCCTGTGTCT GCCTGAGGAT ATCCGGACCC GAGGAGTTGA AGACATCCCA 
GGCTACTACT ACCGTGATGA TGGGATGCAG ATCTGGGGTA TACCCTCCTC ACTGGAGACC 
CGGGAAGCCC TGGTGCAGTA TGTCACCATG GTGATATTCA CCTGCTCCGC CAAGCATGCG 
GCTGTCAGTG CAGGGCAGTT TGACTCCTGT GCTTGGATGC CCAACCTGCC ACCCAGCATG 
CAGCTGCCAC CACCCACCTC CAAAGGCCTG GCAACATGCG AGGGCTTCAT AGCCACCCTC 
CCACCTGTCA ATGCCACATG TGATGTCATC CTTGCTCTCT GGTTGCTGAG CAAGGAGCCT 
GGAGACCAAA GGCCCCTGGG CACCTATCCG GATGAGCACT TCACAGAGGA GGCCCCTCGG 
CGGAGCATCG CCACCTTCCA GAGCCGCCTG GCCCAGATCT CGAGGGGCAT CCAGGAGCGG 
AACCAGGGCC TGGTGCTGCC CTACACCTAC CTAGACCCTC CCCTCATCGA GAACAGCGTC 
TCCATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ALOX15B ( NM_001039130.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001034219.1 Homo sapiens arachidonate 15-lipoxygenase type B (ALOX15B), transcript variant a, mRNA.

Price & Availability↑

CloneID	OHu30473
Clone ID Related Accession (Same CDS sequence)	NM_001039130.1
Accession Version	NM_001039130.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1944bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-07
Organism	Homo sapiens(human)
Product	arachidonate 15-lipoxygenase B isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP327830.1, AF468052.1, CA405703.1, BC063647.1 and CA307212.1. Transcript Variant: This variant (a) lacks an exon in the 3' coding region but maintains the reading frame, compared to variant d. The encoded isoform (a) is shorter than isoform d. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.109638.1, AF468052.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA2142363 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGAGT TCAGGGTCAG GGTGTCCACC GGAGAAGCCT TCGGGGCTGG CACATGGGAC 
AAAGTGTCTG TCAGCATCGT GGGGACCCGG GGAGAGAGCC CCCCACTGCC CCTGGACAAT 
CTCGGCAAGG AGTTCACTGC GGGCGCTGAG GAGGACTTCC AGGTGACGCT CCCGGAGGAC 
GTAGGCCGAG TGCTGCTGCT GCGCGTGCAC AAGGCGCCCC CAGTGCTGCC CCTGCTGGGG 
CCCCTGGCCC CGGATGCCTG GTTCTGCCGC TGGTTCCAGC TGACACCGCC GCGGGGCGGC 
CACCTCCTCT TCCCCTGCTA CCAGTGGCTG GAGGGGGCGG GGACCCTGGT GCTGCAGGAG 
GGTACAGCCA AGGTGTCCTG GGCAGACCAC CACCCTGTGC TCCAGCAACA GCGCCAGGAG 
GAGCTTCAGG CCCGGCAGGA GATGTACCAG TGGAAGGCTT ACAACCCAGG TTGGCCTCAC 
TGCCTGGATG AAAAGACAGT GGAAGACTTG GAGCTCAATA TCAAATACTC CACAGCCAAG 
AATGCCAACT TTTATCTACA GGCTGGCTCT GCTTTTGCAG AGATGAAAAT CAAGGGGTTG 
CTGGACCGCA AGGGGCTCTG GAGGAGTCTG AATGAGATGA AAAGGATCTT CAACTTCCGG 
AGGACCCCAG CAGCTGAGCA CGCATTTGAG CACTGGCAGG AGGACGCCTT CTTCGCCTCC 
CAGTTCCTGA ATGGTCTCAA CCCTGTCCTG ATCCGCCGCT GTCACTACCT CCCAAAGAAC 
TTCCCCGTCA CTGATGCCAT GGTGGCCTCA GTGTTGGGTC CTGGGACCAG CTTGCAGGCT 
GAGCTAGAGA AGGGCTCCCT GTTCTTGGTG GATCACGGCA TCCTCTCTGG CATCCAGACC 
AATGTCATTA ATGGGAAGCC TCAGTTCTCT GCGGCCCCAA TGACCCTGCT ATACCAGAGC 
CCAGGCTGCG GGCCGCTGCT GCCTCTCGCC ATCCAGCTCA GCCAGACCCC CGGCCCAAAC 
AGCCCCATCT TCCTGCCCAC TGATGACAAG TGGGACTGGT TGCTGGCCAA GACCTGGGTG 
CGCAATGCCG AGTTCTCCTT CCATGAGGCC CTCACGCACC TGCTGCACTC ACATCTGCTG 
CCTGAGGTCT TCACCCTGGC TACCCTGCGT CAGCTGCCCC ACTGCCACCC TCTCTTCAAG 
TCCACAGGCA TCGGCATTGA AGGCTTCTCT GAGTTGATAC AGAGGAACAT GAAGCAGCTG 
AACTATTCTC TCCTGTGTCT GCCTGAGGAT ATCCGGACCC GAGGAGTTGA AGACATCCCA 
GGCTACTACT ACCGTGATGA TGGGATGCAG ATCTGGGGTG CAGTGGAACG CTTTGTCTCT 
GAAATCATCG GTATCTACTA CCCAAGTGAT GAGTCTGTCC AAGATGACAG AGAGCTCCAG 
GCCTGGGTCA GAGAGATCTT CTCCAAGGGC TTCCTAAACC AGGAGAGCTC AGGTATACCC 
TCCTCACTGG AGACCCGGGA AGCCCTGGTG CAGTATGTCA CCATGGTGAT ATTCACCTGC 
TCCGCCAAGC ATGCGGCTGT CAGTGCAGGG CAGTTTGACT CCTGTGCTTG GATGCCCAAC 
CTGCCACCCA GCATGCAGCT GCCACCACCC ACCTCCAAAG GCCTGGCAAC ATGCGAGGGC 
TTCATAGCCA CCCTCCCACC TGTCAATGCC ACATGTGATG TCATCCTTGC TCTCTGGTTG 
CTGAGCAAGG AGCCTGGAGA CCAAAGGCCC CTGGGCACCT ATCCGGATGA GCACTTCACA 
GAGGAGGCCC CTCGGCGGAG CATCGCCACC TTCCAGAGCC GCCTGGCCCA GATCTCGAGG 
GGCATCCAGG AGCGGAACCA GGGCCTGGTG CTGCCCTACA CCTACCTAGA CCCTCCCCTC 
ATCGAGAACA GCGTCTCCAT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001034219.1
CDS	117..2060
Translation	MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPEDVGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQEGTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAKNANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFASQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQTNVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQIWGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNATCDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVLPYTYLDPPLIENSVSI

Target ORF information:

RefSeq Version	NM_001039130.1
Organism	Homo sapiens(human)
Definition	Homo sapiens arachidonate 15-lipoxygenase type B (ALOX15B), transcript variant a, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001039130.1

ORF Insert Sequence:

ATGGCCGAGT TCAGGGTCAG GGTGTCCACC GGAGAAGCCT TCGGGGCTGG CACATGGGAC 
AAAGTGTCTG TCAGCATCGT GGGGACCCGG GGAGAGAGCC CCCCACTGCC CCTGGACAAT 
CTCGGCAAGG AGTTCACTGC GGGCGCTGAG GAGGACTTCC AGGTGACGCT CCCGGAGGAC 
GTAGGCCGAG TGCTGCTGCT GCGCGTGCAC AAGGCGCCCC CAGTGCTGCC CCTGCTGGGG 
CCCCTGGCCC CGGATGCCTG GTTCTGCCGC TGGTTCCAGC TGACACCGCC GCGGGGCGGC 
CACCTCCTCT TCCCCTGCTA CCAGTGGCTG GAGGGGGCGG GGACCCTGGT GCTGCAGGAG 
GGTACAGCCA AGGTGTCCTG GGCAGACCAC CACCCTGTGC TCCAGCAACA GCGCCAGGAG 
GAGCTTCAGG CCCGGCAGGA GATGTACCAG TGGAAGGCTT ACAACCCAGG TTGGCCTCAC 
TGCCTGGATG AAAAGACAGT GGAAGACTTG GAGCTCAATA TCAAATACTC CACAGCCAAG 
AATGCCAACT TTTATCTACA GGCTGGCTCT GCTTTTGCAG AGATGAAAAT CAAGGGGTTG 
CTGGACCGCA AGGGGCTCTG GAGGAGTCTG AATGAGATGA AAAGGATCTT CAACTTCCGG 
AGGACCCCAG CAGCTGAGCA CGCATTTGAG CACTGGCAGG AGGACGCCTT CTTCGCCTCC 
CAGTTCCTGA ATGGTCTCAA CCCTGTCCTG ATCCGCCGCT GTCACTACCT CCCAAAGAAC 
TTCCCCGTCA CTGATGCCAT GGTGGCCTCA GTGTTGGGTC CTGGGACCAG CTTGCAGGCT 
GAGCTAGAGA AGGGCTCCCT GTTCTTGGTG GATCACGGCA TCCTCTCTGG CATCCAGACC 
AATGTCATTA ATGGGAAGCC TCAGTTCTCT GCGGCCCCAA TGACCCTGCT ATACCAGAGC 
CCAGGCTGCG GGCCGCTGCT GCCTCTCGCC ATCCAGCTCA GCCAGACCCC CGGCCCAAAC 
AGCCCCATCT TCCTGCCCAC TGATGACAAG TGGGACTGGT TGCTGGCCAA GACCTGGGTG 
CGCAATGCCG AGTTCTCCTT CCATGAGGCC CTCACGCACC TGCTGCACTC ACATCTGCTG 
CCTGAGGTCT TCACCCTGGC TACCCTGCGT CAGCTGCCCC ACTGCCACCC TCTCTTCAAG 
TCCACAGGCA TCGGCATTGA AGGCTTCTCT GAGTTGATAC AGAGGAACAT GAAGCAGCTG 
AACTATTCTC TCCTGTGTCT GCCTGAGGAT ATCCGGACCC GAGGAGTTGA AGACATCCCA 
GGCTACTACT ACCGTGATGA TGGGATGCAG ATCTGGGGTG CAGTGGAACG CTTTGTCTCT 
GAAATCATCG GTATCTACTA CCCAAGTGAT GAGTCTGTCC AAGATGACAG AGAGCTCCAG 
GCCTGGGTCA GAGAGATCTT CTCCAAGGGC TTCCTAAACC AGGAGAGCTC AGGTATACCC 
TCCTCACTGG AGACCCGGGA AGCCCTGGTG CAGTATGTCA CCATGGTGAT ATTCACCTGC 
TCCGCCAAGC ATGCGGCTGT CAGTGCAGGG CAGTTTGACT CCTGTGCTTG GATGCCCAAC 
CTGCCACCCA GCATGCAGCT GCCACCACCC ACCTCCAAAG GCCTGGCAAC ATGCGAGGGC 
TTCATAGCCA CCCTCCCACC TGTCAATGCC ACATGTGATG TCATCCTTGC TCTCTGGTTG 
CTGAGCAAGG AGCCTGGAGA CCAAAGGCCC CTGGGCACCT ATCCGGATGA GCACTTCACA 
GAGGAGGCCC CTCGGCGGAG CATCGCCACC TTCCAGAGCC GCCTGGCCCA GATCTCGAGG 
GGCATCCAGG AGCGGAACCA GGGCCTGGTG CTGCCCTACA CCTACCTAGA CCCTCCCCTC 
ATCGAGAACA GCGTCTCCAT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Structural Dynamics of 15-Lipoxygenase-2 via Hydrogen-Deuterium Exchange.
Biochemistry56(38)5065-5074(2017 09)
Droege KD,Keithly ME,Sanders CR,Armstrong RN,Thompson MK

Membrane-dependent Activities of Human 15-LOX-2 and Its Murine Counterpart: IMPLICATIONS FOR MURINE MODELS OF ATHEROSCLEROSIS.
The Journal of biological chemistry291(37)19413-24(2016 09)
Bender G,Schexnaydre EE,Murphy RC,Uhlson C,Newcomer ME

Strict Regiospecificity of Human Epithelial 15-Lipoxygenase-2 Delineates Its Transcellular Synthesis Potential.
Biochemistry55(20)2832-40(2016 05)
Green AR,Barbour S,Horn T,Carlos J,Raskatov JA,Holman TR

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ALOX15B cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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