Gene Symbol | DDX58 |
Entrez Gene ID | 23586 |
Full Name | DExD/H-box helicase 58 |
Synonyms | RIG-I,RIGI,RLR-1,SGMRT2 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response. [provided by RefSeq, Jul 2008]. |
Disorder MIM: | |
Disorder Html: | Singleton-Merten syndrome 2, 616298 (3) |