Gene Symbol | NNT |
Entrez Gene ID | 23530 |
Full Name | nicotinamide nucleotide transhydrogenase |
Synonyms | GCCD4 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. The resulting NADPH is used for biosynthesis and in free radical detoxification. [provided by RefSeq, Sep 2016]. |
Disorder MIM: | |
Disorder Html: | Glucocorticoid deficiency 4, with or without mineralocorticoid deficiency, 614736 (3) |