LRRC8B gene cDNA ORF clone, Homo sapiens(human)

mRNA	Protein	Name
XM_005270702.4	XP_005270759.1	volume-regulated anion channel subunit LRRC8B isoform X1
XM_005270703.4	XP_005270760.1	volume-regulated anion channel subunit LRRC8B isoform X1
XM_017000885.1	XP_016856374.1	volume-regulated anion channel subunit LRRC8B isoform X1
XM_011541146.2	XP_011539448.1	volume-regulated anion channel subunit LRRC8B isoform X1
NM_001134476.1	NP_001127948.1	volume-regulated anion channel subunit LRRC8B
XM_017000884.1	XP_016856373.1	volume-regulated anion channel subunit LRRC8B isoform X1
XM_005270703.5	XP_005270760.1	volume-regulated anion channel subunit LRRC8B isoform X1
NM_001369819.1	NP_001356748.1	volume-regulated anion channel subunit LRRC8B
XM_011541145.2	XP_011539447.1	volume-regulated anion channel subunit LRRC8B isoform X1
NM_015350.2	NP_056165.1	volume-regulated anion channel subunit LRRC8B
XM_011541144.2	XP_011539446.1	volume-regulated anion channel subunit LRRC8B isoform X1
NM_001134476.2	NP_001127948.1	volume-regulated anion channel subunit LRRC8B
NM_015350.3	NP_056165.1	volume-regulated anion channel subunit LRRC8B
XM_017000883.1	XP_016856372.1	volume-regulated anion channel subunit LRRC8B isoform X1
XM_017000886.1	XP_016856375.1	volume-regulated anion channel subunit LRRC8B isoform X2
XM_005270701.4	XP_005270758.1	volume-regulated anion channel subunit LRRC8B isoform X1
NM_001369817.1	NP_001356746.1	volume-regulated anion channel subunit LRRC8B
XM_011541143.2	XP_011539445.1	volume-regulated anion channel subunit LRRC8B isoform X1
XM_011541148.2	XP_011539450.1	volume-regulated anion channel subunit LRRC8B isoform X2
XM_011541146.3	XP_011539448.1	volume-regulated anion channel subunit LRRC8B isoform X1
NM_015350.4	NP_056165.1	volume-regulated anion channel subunit LRRC8B

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu09061	NM_001134476.2 Latest version!	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
OHu09061	NM_001369817.1 Latest version!	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
OHu09061	NM_001369819.1 Latest version!	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
OHu09061	XM_011541143.2 Latest version!	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
OHu09061	XM_011541144.2 Latest version!	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
OHu09061	XM_005270702.4 Latest version!	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant X8, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
OHu09061	XM_005270701.4 Latest version!	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
OHu09061	XM_017000884.1 Latest version!	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
OHu09061	XM_017000883.1 Latest version!	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
OHu09061	XM_005270703.5 Latest version!	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant X9, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
OHu09061	XM_011541146.3 Latest version!	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant X7, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
OHu09061	XM_011541145.2 Latest version!	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant X6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
OHu09061	XM_017000885.1 Latest version!	Homo sapiens leucine-rich repeat containing 8 family member B (LRRC8B), transcript variant X10, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
OHu66241	XM_017000886.1 Latest version!	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant X11, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu66241	XM_011541148.2 Latest version!	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant X10, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu09061	NM_015350.4 Latest version!	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
View Old Accession Versions >>
OHu09061	XM_005270703.4	Homo sapiens leucine-rich repeat containing 8 family member B (LRRC8B), transcript variant X9, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
OHu09061	NM_001134476.1	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
OHu09061	NM_015350.2	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
OHu09061	XM_011541146.2	Homo sapiens leucine-rich repeat containing 8 family member B (LRRC8B), transcript variant X7, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
OHu09061	NM_015350.3	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
Hide Old Accession Versions >>

LRRC8B ( NM_001134476.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001127948.1 Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu09061
Clone ID Related Accession (Same CDS sequence)	XM_005270702.4 , XM_005270703.4 , XM_017000885.1 , XM_011541146.2 , NM_001134476.1 , XM_017000884.1 , XM_005270703.5 , NM_001369819.1 , XM_011541145.2 , NM_015350.2 , XM_011541144.2 , NM_001134476.2 , NM_015350.3 , XM_017000883.1 , XM_005270701.4 , NM_001369817.1 , XM_011541143.2 , XM_011541146.3 , NM_015350.4
Accession Version	NM_001134476.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2412bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-20
Organism	Homo sapiens(human)
Product	volume-regulated anion channel subunit LRRC8B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI459217.1, BC060782.1, D86984.2, AC099569.2 and AW022123.1. Transcript Variant: This variant (2) uses different segments for its 5' UTR, compared to variant 1. Variants 1 and 2 both encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC060782.1, SRR1803613.138759.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END##

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001127948.1
CDS	508..2919
Translation	MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKVEFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKFFPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRPLKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEKVKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYKRYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIPDVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQDKIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNLRTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIVEENLLNTLPLPVTERLQTCLDKC

Target ORF information:

RefSeq Version	NM_001134476.1
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001134476.1

ORF Insert Sequence:

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRRC8B ( NM_001369819.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001356748.1 Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu09061
Clone ID Related Accession (Same CDS sequence)	XM_005270702.4 , XM_005270703.4 , XM_017000885.1 , XM_011541146.2 , NM_001134476.1 , XM_017000884.1 , XM_005270703.5 , NM_001369819.1 , XM_011541145.2 , NM_015350.2 , XM_011541144.2 , NM_001134476.2 , NM_015350.3 , XM_017000883.1 , XM_005270701.4 , NM_001369817.1 , XM_011541143.2 , XM_011541146.3 , NM_015350.4
Accession Version	NM_001369819.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2412bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	volume-regulated anion channel subunit LRRC8B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC099569.2. On Apr 19, 2019 this sequence version replaced XM_005270702.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.56819.1, SRR1803615.223176.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END##

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001356748.1
CDS	451..2862
Translation	MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKVEFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKFFPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRPLKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEKVKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYKRYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIPDVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQDKIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNLRTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIVEENLLNTLPLPVTERLQTCLDKC

Target ORF information:

RefSeq Version	NM_001369819.1
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001369819.1

ORF Insert Sequence:

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRRC8B ( NM_015350.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_056165.1 Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu09061
Clone ID Related Accession (Same CDS sequence)	XM_005270702.4 , XM_005270703.4 , XM_017000885.1 , XM_011541146.2 , NM_001134476.1 , XM_017000884.1 , XM_005270703.5 , NM_001369819.1 , XM_011541145.2 , NM_015350.2 , XM_011541144.2 , NM_001134476.2 , NM_015350.3 , XM_017000883.1 , XM_005270701.4 , NM_001369817.1 , XM_011541143.2 , XM_011541146.3 , NM_015350.4
Accession Version	NM_015350.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2412bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-19
Organism	Homo sapiens(human)
Product	volume-regulated anion channel subunit LRRC8B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF385436.1, D86984.2, AC099569.2 and AW022123.1. On Aug 29, 2008 this sequence version replaced NM_015350.1. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AF385436.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056165.1
CDS	565..2976
Translation	MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKVEFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKFFPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRPLKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEKVKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYKRYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIPDVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQDKIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNLRTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIVEENLLNTLPLPVTERLQTCLDKC

Target ORF information:

RefSeq Version	NM_015350.2
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015350.2

ORF Insert Sequence:

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRRC8B ( NM_001134476.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001127948.1 Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu09061
Clone ID Related Accession (Same CDS sequence)	XM_005270702.4 , XM_005270703.4 , XM_017000885.1 , XM_011541146.2 , NM_001134476.1 , XM_017000884.1 , XM_005270703.5 , NM_001369819.1 , XM_011541145.2 , NM_015350.2 , XM_011541144.2 , NM_001134476.2 , NM_015350.3 , XM_017000883.1 , XM_005270701.4 , NM_001369817.1 , XM_011541143.2 , XM_011541146.3 , NM_015350.4
Accession Version	NM_001134476.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2412bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	volume-regulated anion channel subunit LRRC8B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC099569.2, BI459217.1, BC060782.1, D86984.2 and AW022123.1. On Jun 2, 2019 this sequence version replaced NM_001134476.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.138759.1, SRR1803617.179849.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END##

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001127948.1
CDS	517..2928
Translation	MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKVEFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKFFPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRPLKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEKVKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYKRYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIPDVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQDKIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNLRTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIVEENLLNTLPLPVTERLQTCLDKC

Target ORF information:

RefSeq Version	NM_001134476.2
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001134476.2

ORF Insert Sequence:

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRRC8B ( NM_015350.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_056165.1 Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu09061
Clone ID Related Accession (Same CDS sequence)	XM_005270702.4 , XM_005270703.4 , XM_017000885.1 , XM_011541146.2 , NM_001134476.1 , XM_017000884.1 , XM_005270703.5 , NM_001369819.1 , XM_011541145.2 , NM_015350.2 , XM_011541144.2 , NM_001134476.2 , NM_015350.3 , XM_017000883.1 , XM_005270701.4 , NM_001369817.1 , XM_011541143.2 , XM_011541146.3 , NM_015350.4
Accession Version	NM_015350.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2412bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-01
Organism	Homo sapiens(human)
Product	volume-regulated anion channel subunit LRRC8B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC099569.2. On or before Apr 19, 2019 this sequence version replaced XM_011541145.2, NM_015350.2. Transcript Variant: This variant (1) represents the longest transcript. Variants 1 and 2 both encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.27625.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END##

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056165.1
CDS	834..3245
Translation	MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKVEFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKFFPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRPLKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEKVKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYKRYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIPDVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQDKIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNLRTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIVEENLLNTLPLPVTERLQTCLDKC

Target ORF information:

RefSeq Version	NM_015350.3
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015350.3

ORF Insert Sequence:

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRRC8B ( NM_001369817.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001356746.1 Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu09061
Clone ID Related Accession (Same CDS sequence)	XM_005270702.4 , XM_005270703.4 , XM_017000885.1 , XM_011541146.2 , NM_001134476.1 , XM_017000884.1 , XM_005270703.5 , NM_001369819.1 , XM_011541145.2 , NM_015350.2 , XM_011541144.2 , NM_001134476.2 , NM_015350.3 , XM_017000883.1 , XM_005270701.4 , NM_001369817.1 , XM_011541143.2 , XM_011541146.3 , NM_015350.4
Accession Version	NM_001369817.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2412bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	volume-regulated anion channel subunit LRRC8B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC099569.2. On Apr 19, 2019 this sequence version replaced XM_005270701.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.106562.1, SRR1803612.248463.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END##

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001356746.1
CDS	426..2837
Translation	MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKVEFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKFFPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRPLKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEKVKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYKRYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIPDVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQDKIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNLRTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIVEENLLNTLPLPVTERLQTCLDKC

Target ORF information:

RefSeq Version	NM_001369817.1
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001369817.1

ORF Insert Sequence:

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRRC8B ( XM_005270702.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005270759.1 Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant X8, mRNA.

Price & Availability↑

CloneID	OHu09061
Clone ID Related Accession (Same CDS sequence)	XM_005270702.4 , XM_005270703.4 , XM_017000885.1 , XM_011541146.2 , NM_001134476.1 , XM_017000884.1 , XM_005270703.5 , NM_001369819.1 , XM_011541145.2 , NM_015350.2 , XM_011541144.2 , NM_001134476.2 , NM_015350.3 , XM_017000883.1 , XM_005270701.4 , NM_001369817.1 , XM_011541143.2 , XM_011541146.3 , NM_015350.4
Accession Version	XM_005270702.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2412bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-25
Organism	Homo sapiens(human)
Product	volume-regulated anion channel subunit LRRC8B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005270702.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Homo sapiens Annotation Release 109 Annotation Version :: 109 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005270759.1
CDS	455..2866
Translation	MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKVEFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKFFPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRPLKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEKVKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYKRYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIPDVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQDKIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNLRTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIVEENLLNTLPLPVTERLQTCLDKC

Target ORF information:

RefSeq Version	XM_005270702.4
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant X8, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005270702.4

ORF Insert Sequence:

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRRC8B ( XM_005270703.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005270760.1 Homo sapiens leucine-rich repeat containing 8 family member B (LRRC8B), transcript variant X9, mRNA.

Price & Availability↑

CloneID	OHu09061
Clone ID Related Accession (Same CDS sequence)	XM_005270702.4 , XM_005270703.4 , XM_017000885.1 , XM_011541146.2 , NM_001134476.1 , XM_017000884.1 , XM_005270703.5 , NM_001369819.1 , XM_011541145.2 , NM_015350.2 , XM_011541144.2 , NM_001134476.2 , NM_015350.3 , XM_017000883.1 , XM_005270701.4 , NM_001369817.1 , XM_011541143.2 , XM_011541146.3 , NM_015350.4
Accession Version	XM_005270703.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2412bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	volume-regulated anion channel subunit LRRC8B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005270703.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005270760.1
CDS	2202..4613
Translation	MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKVEFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKFFPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRPLKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEKVKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYKRYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIPDVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQDKIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNLRTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIVEENLLNTLPLPVTERLQTCLDKC

Target ORF information:

RefSeq Version	XM_005270703.4
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine-rich repeat containing 8 family member B (LRRC8B), transcript variant X9, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005270703.4

ORF Insert Sequence:

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRRC8B ( XM_017000885.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016856374.1 Homo sapiens leucine-rich repeat containing 8 family member B (LRRC8B), transcript variant X10, mRNA.

Price & Availability↑

CloneID	OHu09061
Clone ID Related Accession (Same CDS sequence)	XM_005270702.4 , XM_005270703.4 , XM_017000885.1 , XM_011541146.2 , NM_001134476.1 , XM_017000884.1 , XM_005270703.5 , NM_001369819.1 , XM_011541145.2 , NM_015350.2 , XM_011541144.2 , NM_001134476.2 , NM_015350.3 , XM_017000883.1 , XM_005270701.4 , NM_001369817.1 , XM_011541143.2 , XM_011541146.3 , NM_015350.4
Accession Version	XM_017000885.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2412bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	volume-regulated anion channel subunit LRRC8B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016856374.1
CDS	526..2937
Translation	MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKVEFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKFFPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRPLKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEKVKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYKRYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIPDVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQDKIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNLRTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIVEENLLNTLPLPVTERLQTCLDKC

Target ORF information:

RefSeq Version	XM_017000885.1
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine-rich repeat containing 8 family member B (LRRC8B), transcript variant X10, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017000885.1

ORF Insert Sequence:

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRRC8B ( XM_011541146.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011539448.1 Homo sapiens leucine-rich repeat containing 8 family member B (LRRC8B), transcript variant X7, mRNA.

Price & Availability↑

CloneID	OHu09061
Clone ID Related Accession (Same CDS sequence)	XM_005270702.4 , XM_005270703.4 , XM_017000885.1 , XM_011541146.2 , NM_001134476.1 , XM_017000884.1 , XM_005270703.5 , NM_001369819.1 , XM_011541145.2 , NM_015350.2 , XM_011541144.2 , NM_001134476.2 , NM_015350.3 , XM_017000883.1 , XM_005270701.4 , NM_001369817.1 , XM_011541143.2 , XM_011541146.3 , NM_015350.4
Accession Version	XM_011541146.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2412bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	volume-regulated anion channel subunit LRRC8B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011541146.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011539448.1
CDS	2259..4670
Translation	MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKVEFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKFFPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRPLKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEKVKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYKRYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIPDVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQDKIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNLRTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIVEENLLNTLPLPVTERLQTCLDKC

Target ORF information:

RefSeq Version	XM_011541146.2
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine-rich repeat containing 8 family member B (LRRC8B), transcript variant X7, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011541146.2

ORF Insert Sequence:

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRRC8B ( XM_017000884.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016856373.1 Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu09061
Clone ID Related Accession (Same CDS sequence)	XM_005270702.4 , XM_005270703.4 , XM_017000885.1 , XM_011541146.2 , NM_001134476.1 , XM_017000884.1 , XM_005270703.5 , NM_001369819.1 , XM_011541145.2 , NM_015350.2 , XM_011541144.2 , NM_001134476.2 , NM_015350.3 , XM_017000883.1 , XM_005270701.4 , NM_001369817.1 , XM_011541143.2 , XM_011541146.3 , NM_015350.4
Accession Version	XM_017000884.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2412bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	volume-regulated anion channel subunit LRRC8B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016856373.1
CDS	2356..4767
Translation	MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKVEFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKFFPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRPLKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEKVKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYKRYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIPDVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQDKIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNLRTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIVEENLLNTLPLPVTERLQTCLDKC

Target ORF information:

RefSeq Version	XM_017000884.1
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017000884.1

ORF Insert Sequence:

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRRC8B ( XM_005270703.5 ) cDNA ORF clone, Homo sapiens(human) -> XP_005270760.1 Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant X9, mRNA.

Price & Availability↑

CloneID	OHu09061
Clone ID Related Accession (Same CDS sequence)	XM_005270702.4 , XM_005270703.4 , XM_017000885.1 , XM_011541146.2 , NM_001134476.1 , XM_017000884.1 , XM_005270703.5 , NM_001369819.1 , XM_011541145.2 , NM_015350.2 , XM_011541144.2 , NM_001134476.2 , NM_015350.3 , XM_017000883.1 , XM_005270701.4 , NM_001369817.1 , XM_011541143.2 , XM_011541146.3 , NM_015350.4
Accession Version	XM_005270703.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2412bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	volume-regulated anion channel subunit LRRC8B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005270703.4. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005270760.1
CDS	2203..4614
Translation	MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKVEFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKFFPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRPLKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEKVKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYKRYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIPDVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQDKIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNLRTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIVEENLLNTLPLPVTERLQTCLDKC

Target ORF information:

RefSeq Version	XM_005270703.5
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant X9, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005270703.5

ORF Insert Sequence:

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRRC8B ( XM_011541145.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011539447.1 Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant X6, mRNA.

Price & Availability↑

CloneID	OHu09061
Clone ID Related Accession (Same CDS sequence)	XM_005270702.4 , XM_005270703.4 , XM_017000885.1 , XM_011541146.2 , NM_001134476.1 , XM_017000884.1 , XM_005270703.5 , NM_001369819.1 , XM_011541145.2 , NM_015350.2 , XM_011541144.2 , NM_001134476.2 , NM_015350.3 , XM_017000883.1 , XM_005270701.4 , NM_001369817.1 , XM_011541143.2 , XM_011541146.3 , NM_015350.4
Accession Version	XM_011541145.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2412bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-25
Organism	Homo sapiens(human)
Product	volume-regulated anion channel subunit LRRC8B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011541145.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Homo sapiens Annotation Release 109 Annotation Version :: 109 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011539447.1
CDS	829..3240
Translation	MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKVEFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKFFPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRPLKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEKVKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYKRYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIPDVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQDKIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNLRTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIVEENLLNTLPLPVTERLQTCLDKC

Target ORF information:

RefSeq Version	XM_011541145.2
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant X6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011541145.2

ORF Insert Sequence:

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRRC8B ( XM_011541144.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011539446.1 Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant X5, mRNA.

Price & Availability↑

CloneID	OHu09061
Clone ID Related Accession (Same CDS sequence)	XM_005270702.4 , XM_005270703.4 , XM_017000885.1 , XM_011541146.2 , NM_001134476.1 , XM_017000884.1 , XM_005270703.5 , NM_001369819.1 , XM_011541145.2 , NM_015350.2 , XM_011541144.2 , NM_001134476.2 , NM_015350.3 , XM_017000883.1 , XM_005270701.4 , NM_001369817.1 , XM_011541143.2 , XM_011541146.3 , NM_015350.4
Accession Version	XM_011541144.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2412bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	volume-regulated anion channel subunit LRRC8B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011541144.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011539446.1
CDS	804..3215
Translation	MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKVEFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKFFPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRPLKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEKVKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYKRYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIPDVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQDKIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNLRTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIVEENLLNTLPLPVTERLQTCLDKC

Target ORF information:

RefSeq Version	XM_011541144.2
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011541144.2

ORF Insert Sequence:

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRRC8B ( XM_017000883.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016856372.1 Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu09061
Clone ID Related Accession (Same CDS sequence)	XM_005270702.4 , XM_005270703.4 , XM_017000885.1 , XM_011541146.2 , NM_001134476.1 , XM_017000884.1 , XM_005270703.5 , NM_001369819.1 , XM_011541145.2 , NM_015350.2 , XM_011541144.2 , NM_001134476.2 , NM_015350.3 , XM_017000883.1 , XM_005270701.4 , NM_001369817.1 , XM_011541143.2 , XM_011541146.3 , NM_015350.4
Accession Version	XM_017000883.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2412bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	volume-regulated anion channel subunit LRRC8B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016856372.1
CDS	1454..3865
Translation	MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKVEFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKFFPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRPLKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEKVKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYKRYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIPDVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQDKIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNLRTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIVEENLLNTLPLPVTERLQTCLDKC

Target ORF information:

RefSeq Version	XM_017000883.1
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017000883.1

ORF Insert Sequence:

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRRC8B ( XM_005270701.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005270758.1 Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu09061
Clone ID Related Accession (Same CDS sequence)	XM_005270702.4 , XM_005270703.4 , XM_017000885.1 , XM_011541146.2 , NM_001134476.1 , XM_017000884.1 , XM_005270703.5 , NM_001369819.1 , XM_011541145.2 , NM_015350.2 , XM_011541144.2 , NM_001134476.2 , NM_015350.3 , XM_017000883.1 , XM_005270701.4 , NM_001369817.1 , XM_011541143.2 , XM_011541146.3 , NM_015350.4
Accession Version	XM_005270701.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2412bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-25
Organism	Homo sapiens(human)
Product	volume-regulated anion channel subunit LRRC8B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005270701.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Homo sapiens Annotation Release 109 Annotation Version :: 109 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005270758.1
CDS	434..2845
Translation	MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKVEFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKFFPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRPLKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEKVKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYKRYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIPDVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQDKIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNLRTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIVEENLLNTLPLPVTERLQTCLDKC

Target ORF information:

RefSeq Version	XM_005270701.4
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005270701.4

ORF Insert Sequence:

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRRC8B ( XM_011541143.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011539445.1 Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu09061
Clone ID Related Accession (Same CDS sequence)	XM_005270702.4 , XM_005270703.4 , XM_017000885.1 , XM_011541146.2 , NM_001134476.1 , XM_017000884.1 , XM_005270703.5 , NM_001369819.1 , XM_011541145.2 , NM_015350.2 , XM_011541144.2 , NM_001134476.2 , NM_015350.3 , XM_017000883.1 , XM_005270701.4 , NM_001369817.1 , XM_011541143.2 , XM_011541146.3 , NM_015350.4
Accession Version	XM_011541143.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2412bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	volume-regulated anion channel subunit LRRC8B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011541143.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011539445.1
CDS	492..2903
Translation	MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKVEFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKFFPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRPLKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEKVKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYKRYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIPDVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQDKIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNLRTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIVEENLLNTLPLPVTERLQTCLDKC

Target ORF information:

RefSeq Version	XM_011541143.2
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011541143.2

ORF Insert Sequence:

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRRC8B ( XM_011541146.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011539448.1 Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant X7, mRNA.

Price & Availability↑

CloneID	OHu09061
Clone ID Related Accession (Same CDS sequence)	XM_005270702.4 , XM_005270703.4 , XM_017000885.1 , XM_011541146.2 , NM_001134476.1 , XM_017000884.1 , XM_005270703.5 , NM_001369819.1 , XM_011541145.2 , NM_015350.2 , XM_011541144.2 , NM_001134476.2 , NM_015350.3 , XM_017000883.1 , XM_005270701.4 , NM_001369817.1 , XM_011541143.2 , XM_011541146.3 , NM_015350.4
Accession Version	XM_011541146.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2412bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	volume-regulated anion channel subunit LRRC8B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011541146.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011539448.1
CDS	2260..4671
Translation	MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKVEFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKFFPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRPLKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEKVKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYKRYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIPDVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQDKIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNLRTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIVEENLLNTLPLPVTERLQTCLDKC

Target ORF information:

RefSeq Version	XM_011541146.3
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant X7, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011541146.3

ORF Insert Sequence:

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRRC8B ( XM_017000886.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016856375.1 Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant X11, mRNA.

Price & Availability↑

CloneID	OHu66241
Clone ID Related Accession (Same CDS sequence)	XM_017000886.1 , XM_011541148.2
Accession Version	XM_017000886.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2196bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	volume-regulated anion channel subunit LRRC8B isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATG ATTCTTCAGA GCCTTTAACA 
TATGAATATG CATTGTGCTT CTCCAAGGAG AGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016856375.1
CDS	430..2625
Translation	MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKVEFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKFFPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRPLKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEKVKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYKRYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIPDVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQDKIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNLRTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNDSSEPLTYEYALCFSKER

Target ORF information:

RefSeq Version	XM_017000886.1
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant X11, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017000886.1

ORF Insert Sequence:

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATG ATTCTTCAGA GCCTTTAACA 
TATGAATATG CATTGTGCTT CTCCAAGGAG AGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRRC8B ( XM_011541148.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011539450.1 Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant X10, mRNA.

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CloneID	OHu66241
Clone ID Related Accession (Same CDS sequence)	XM_017000886.1 , XM_011541148.2
Accession Version	XM_011541148.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2196bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	volume-regulated anion channel subunit LRRC8B isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011541148.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATG ATTCTTCAGA GCCTTTAACA 
TATGAATATG CATTGTGCTT CTCCAAGGAG AGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011539450.1
CDS	480..2675
Translation	MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKVEFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKFFPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRPLKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEKVKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYKRYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIPDVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQDKIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNLRTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNDSSEPLTYEYALCFSKER

Target ORF information:

RefSeq Version	XM_011541148.2
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant X10, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011541148.2

ORF Insert Sequence:

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATG ATTCTTCAGA GCCTTTAACA 
TATGAATATG CATTGTGCTT CTCCAAGGAG AGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRRC8B ( NM_015350.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_056165.1 Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant 1, mRNA.

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CloneID	OHu09061
Clone ID Related Accession (Same CDS sequence)	XM_005270702.4 , XM_005270703.4 , XM_017000885.1 , XM_011541146.2 , NM_001134476.1 , XM_017000884.1 , XM_005270703.5 , NM_001369819.1 , XM_011541145.2 , NM_015350.2 , XM_011541144.2 , NM_001134476.2 , NM_015350.3 , XM_017000883.1 , XM_005270701.4 , NM_001369817.1 , XM_011541143.2 , XM_011541146.3 , NM_015350.4
Accession Version	NM_015350.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2412bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	volume-regulated anion channel subunit LRRC8B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC099569.2. On Aug 28, 2019 this sequence version replaced NM_015350.3. Transcript Variant: This variant (1) represents the longest transcript. Variants 1 and 2 both encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.27625.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END##

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056165.1
CDS	843..3254
Translation	MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKVEFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKFFPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRPLKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEKVKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYKRYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIPDVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQDKIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNLRTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIVEENLLNTLPLPVTERLQTCLDKC

Target ORF information:

RefSeq Version	NM_015350.4
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat containing 8 VRAC subunit B (LRRC8B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015350.4

ORF Insert Sequence:

ATGATTACAC TAACTGAGCT AAAATGCTTA GCAGATGCCC AGTCATCTTA TCACATCTTA 
AAACCATGGT GGGACGTCTT CTGGTATTAC ATCACACTGA TCATGCTGCT GGTGGCCGTG 
CTGGCCGGAG CTCTCCAGCT GACGCAGAGC AGGGTTCTGT GCTGTCTTCC ATGCAAAGTG 
GAATTTGACA ATCACTGTGC CGTGCCTTGG GACATCCTGA AAGCCAGCAT GAACACATCC 
TCTAATCCTG GGACACCGCT TCCGCTCCCC CTCCGAATTC AGAATGACCT CCACCGACAG 
CAGTACTCCT ATATTGATGC CGTCTGTTAC GAGAAACAGC TCCATTGGTT TGCAAAGTTT 
TTCCCCTATC TGGTGCTCTT GCACACGCTC ATCTTTGCAG CCTGCAGCAA CTTTTGGCTT 
CACTACCCCA GTACCAGTTC CAGGCTCGAG CATTTTGTGG CCATCCTTCA CAAGTGCTTC 
GATTCTCCAT GGACCACCCG CGCCCTTTCA GAAACAGTGG CTGAGCAGTC AGTGAGGCCT 
CTGAAACTCT CCAAGTCCAA GATTTTGCTT TCGTCCTCAG GGTGTTCAGC TGACATAGAT 
TCCGGCAAAC AGTCATTGCC CTACCCACAG CCAGGTTTGG AGTCAGCTGG CATAGAAAGC 
CCAACTTCCA GTGTCCTGGA CAAGAAGGAG GGTGAACAGG CCAAAGCCAT CTTTGAAAAA 
GTGAAAAGAT TCCGCATGCA TGTGGAGCAG AAGGACATCA TTTATAGAGT ATATCTGAAA 
CAGATAATAG TCAAAGTCAT TTTGTTTGTG CTCATCATAA CTTATGTTCC ATATTTTTTA 
ACCCACATCA CTCTTGAAAT CGACTGTTCA GTTGATGTGC AGGCTTTTAC AGGATATAAG 
CGCTACCAGT GTGTCTATTC CTTGGCAGAA ATCTTTAAGG TCCTGGCTTC ATTTTATGTC 
ATTTTGGTTA TACTTTATGG TCTGACCTCT TCCTACAGCC TGTGGTGGAT GCTGAGGAGT 
TCCCTGAAGC AATATTCCTT TGAGGCGTTA AGAGAAAAAA GCAACTACAG TGACATCCCT 
GATGTCAAGA ATGACTTTGC CTTCATCCTT CATCTGGCTG ATCAGTATGA TCCTCTTTAT 
TCCAAACGCT TCTCCATATT CCTATCAGAG GTCAGTGAGA ACAAACTGAA ACAGATCAAC 
CTCAATAATG AATGGACAGT TGAGAAACTG AAAAGTAAGC TTGTGAAAAA TGCCCAGGAC 
AAGATAGAAC TGCATCTTTT TATGCTCAAC GGTCTTCCAG ACAATGTCTT TGAGTTAACT 
GAAATGGAAG TGCTAAGCCT GGAGCTTATC CCAGAGGTGA AGCTGCCCTC TGCAGTCTCA 
CAGCTGGTCA ACCTCAAGGA GCTTCGTGTG TACCATTCAT CTCTGGTCGT AGACCATCCT 
GCACTGGCCT TTCTAGAGGA GAATTTAAAA ATCCTCCGCC TGAAATTTAC TGAAATGGGA 
AAAATCCCAC GCTGGGTATT TCACCTCAAG AATCTCAAGG AACTTTATCT TTCGGGCTGT 
GTTCTCCCTG AACAGTTGAG TACTATGCAG TTGGAGGGCT TTCAGGACTT AAAAAATCTA 
AGGACCCTGT ACTTGAAGAG CAGCCTCTCC CGGATCCCAC AAGTTGTTAC AGACCTCCTG 
CCTTCATTGC AGAAACTGTC CCTTGATAAT GAGGGAAGCA AACTGGTTGT GTTGAACAAC 
TTGAAAAAGA TGGTCAATCT GAAAAGCCTA GAACTGATCA GCTGTGACCT GGAACGCATC 
CCACATTCCA TTTTCAGCCT GAATAATTTG CATGAGTTAG ACCTAAGGGA AAATAACCTT 
AAAACTGTGG AAGAGATCAT TAGCTTTCAG CATCTTCAGA ATCTTTCCTG CTTAAAGTTG 
TGGCACAATA ACATTGCTTA TATTCCTGCA CAGATTGGGG CATTATCTAA CCTAGAGCAG 
CTCTCTTTGG ACCATAATAA TATTGAGAAT CTGCCCTTGC AGCTTTTCCT ATGCACTAAA 
CTACATTATT TGGATCTAAG CTATAACCAC TTGACCTTCA TTCCAGAAGA AATCCAGTAT 
CTGAGTAATT TGCAGTACTT TGCTGTGACC AACAACAATA TTGAGATGCT ACCAGATGGG 
CTGTTTCAGT GCAAAAAGCT GCAGTGTTTA CTTTTGGGGA AAAATAGCTT GATGAATTTG 
TCCCCTCATG TGGGTGAGCT GTCAAACCTT ACTCATCTGG AGCTCATTGG TAATTACCTG 
GAAACACTTC CTCCTGAACT AGAAGGATGT CAGTCCCTAA AACGGAACTG TCTGATTGTT 
GAGGAGAACT TGCTCAATAC TCTTCCTCTC CCTGTAACAG AACGTTTACA GACGTGCTTA 
GACAAATGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gene Symbol	LRRC8B
Entrez Gene ID	23507
Full Name	leucine rich repeat containing 8 VRAC subunit B
Synonyms	TA-LRRP,TALRRP
General protein information	Preferred Names leucine rich repeat containing 8 VRAC subunit B Names volume-regulated anion channel subunit LRRC8B T-cell activation leucine repeat-rich protein leucine rich repeat containing 8 family member B leucine-rich repeat-containing protein 8B
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p22.2
Disorder MIM:	612888

Homo sapiens (human)	LRRC8B	NP_056165.1
Rattus norvegicus (Norway rat)	Lrrc8b	NP_001100674.1
Gallus gallus (chicken)	LRRC8B	XP_004936694.1
	LRRC8B	XP_002801670.1
Pan troglodytes (chimpanzee)	LRRC8B	XP_001150409.1
Bos taurus (cattle)	LRRC8B	XP_005204398.1
Mus musculus (house mouse)	Lrrc8b	NP_001028722.1
Canis lupus familiaris (dog)	LRRC8B	XP_005622010.1
Xenopus tropicalis (tropical clawed frog)	lrrc8b	XP_002941172.1

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LRRC8B cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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