ABCA5 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ABCA5
Entrez Gene ID	23461
Full Name	ATP binding cassette subfamily A member 5
Synonyms	ABC13,EST90625
General protein information	Preferred Names ATP binding cassette subfamily A member 5 Names ATP-binding cassette sub-family A member 5 ATP-binding cassette A5 ATP-binding cassette, sub-family A (ABC1), member 5
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q24.3
Summary	The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24, but neither the substrate nor the function of this gene is known. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008].
Disorder MIM:	612503

mRNA and Protein(s)

mRNA	Protein	Name
NM_018672.4	NP_061142.2	ATP-binding cassette sub-family A member 5
NM_172232.3	NP_758424.1	ATP-binding cassette sub-family A member 5
NM_172232.4	NP_758424.1	ATP-binding cassette sub-family A member 5

Pathways from BioSystems

Homologies

	ABCA5	XP_002800626.1
Canis lupus familiaris (dog)	ABCA5	XP_005624345.1
Mus musculus (house mouse)	Abca5	NP_671752.2
Xenopus tropicalis (tropical clawed frog)	abca5	NP_001135599.1
Pan troglodytes (chimpanzee)	ABCA5	XP_001166579.1
Bos taurus (cattle)	ABCA5	XP_005221403.1
Gallus gallus (chicken)	ABCA5	XP_004946295.1
Danio rerio (zebrafish)	abca5	NP_001092716.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010416	XP_311532.4
Homo sapiens (human)	ABCA5	NP_061142.2
Rattus norvegicus (Norway rat)	Abca5	NP_775429.1

Gene Ontology
Bibliography

Related articles in PubMed

ABCA5 regulates amyloid-? peptide production and is associated with Alzheimer's disease neuropathology.
Fu Y, Hsiao JH, Paxinos G, Halliday GM, Kim WS
Journal of Alzheimer's disease : JAD43(3)857-69(2015)

Mutations in the cholesterol transporter gene ABCA5 are associated with excessive hair overgrowth.
DeStefano GM, Kurban M, Anyane-Yeboa K, Dall'Armi C, Di Paolo G, Feenstra H, Silverberg N, Rohena L, L?pez-Cepeda LD, Jobanputra V, Fantauzzo KA, Kiuru M, Tadin-Strapps M, Sobrino A, Vitebsky A, Warburton D, Levy B, Salas-Alanis JC, Christiano AM
PLoS genetics10(5)e1004333(2014)

Identification of CBX3 and ABCA5 as putative biomarkers for tumor stem cells in osteosarcoma.
Saini V, Hose CD, Monks A, Nagashima K, Han B, Newton DL, Millione A, Shah J, Hollingshead MG, Hite KM, Burkett MW, Delosh RM, Silvers TE, Scudiero DA, Shoemaker RH
PloS one7(8)e41401(2012)

Changes in sphingomyelin level affect alpha-synuclein and ABCA5 expression.
Kim WS, Halliday GM
Journal of Parkinson's disease2(1)41-6(2012)

ATP-binding cassette transporter ABCB5 gene is expressed with variability in malignant melanoma.
V?squez-Moctezuma I, Meraz-R?os MA, Villanueva-L?pez CG, Maga?a M, Mart?nez-Macias R, S?nchez-Gonz?lez DJ, Garc?a-Sierra F, Herrera-Gonz?lez NE
Actas dermo-sifiliograficas101(4)341-8(2010 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This report represents the first extensive expression and functional study of ABCA5 in the human brain and our data suggest a plausible function of ABCA5 in the brain as a cholesterol transporter associated with Abeta generation
Title: ABCA5 regulates amyloid-? peptide production and is associated with Alzheimer's disease neuropathology.

our findings support ABCA5 as a gene underlying the congenital generalized hypertrichosis terminalis phenotype and suggest a novel, previously unrecognized role for this gene in regulating hair growth.
Title: Mutations in the cholesterol transporter gene ABCA5 are associated with excessive hair overgrowth.

Identification of CBX3 and ABCA5 as putative biomarkers for tumor stem cells in osteosarcoma.
Title: Identification of CBX3 and ABCA5 as putative biomarkers for tumor stem cells in osteosarcoma.

The expression of ABCA5 was significantly elevated in parkinson disease brains compared to age- and gender-matched control brains.
Title: Changes in sphingomyelin level affect alpha-synuclein and ABCA5 expression.

The ABCB5 gene may be related to the properties of chemoresistance and aggressiveness of melanoma
Title: ATP-binding cassette transporter ABCB5 gene is expressed with variability in malignant melanoma.

The following ABCA5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ABCA5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu23763	NM_018672.4 Latest version!	Homo sapiens ATP binding cassette subfamily A member 5 (ABCA5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$811.30 $1159.00
OHu23763	NM_172232.4 Latest version!	Homo sapiens ATP binding cassette subfamily A member 5 (ABCA5), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$811.30 $1159.00
View Old Accession Versions >>
OHu23763	NM_172232.3	Homo sapiens ATP binding cassette subfamily A member 5 (ABCA5), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$811.30 $1159.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ABCA5 ( NM_018672.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_061142.2 Homo sapiens ATP binding cassette subfamily A member 5 (ABCA5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu23763
Clone ID Related Accession (Same CDS sequence)	NM_018672.4 , NM_172232.3 , NM_172232.4
Accession Version	NM_018672.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4929bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	ATP-binding cassette sub-family A member 5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC115085.4, AY028897.1, AJ275973.3, AK058170.1, AC005495.2 and KF456324.1. On Jan 17, 2014 this sequence version replaced NM_018672.3. Transcript Variant: This variant (1) represents the longer transcript variant. It contains a distinct 5' UTR compared to transcript variant 2, but encodes the same protein. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The extent of this RefSeq transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY028897.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCACTG CAATTAGGGA GGTAGGAGTT TGGAGACAGA CCAGAACACT TCTACTGAAG 
AATTACTTAA TTAAATGCAG AACCAAAAAG AGTAGTGTTC AGGAAATTCT TTTTCCACTA 
TTTTTTTTAT TTTGGTTAAT ATTAATTAGC ATGATGCATC CAAATAAGAA ATATGAAGAA 
GTGCCTAATA TAGAACTCAA TCCTATGGAC AAGTTTACTC TTTCTAATCT AATTCTTGGA 
TATACTCCAG TGACTAATAT TACAAGCAGC ATCATGCAGA AAGTGTCTAC TGATCATCTA 
CCTGATGTCA TAATTACTGA AGAATATACA AATGAAAAAG AAATGTTAAC ATCCAGTCTC 
TCTAAGCCGA GCAACTTTGT AGGTGTGGTT TTCAAAGACT CCATGTCCTA TGAACTTCGT 
TTTTTTCCTG ATATGATTCC AGTATCTTCT ATTTATATGG ATTCAAGAGC TGGCTGTTCA 
AAATCATGTG AGGCTGCTCA GTACTGGTCC TCAGGTTTCA CAGTTTTACA AGCATCCATA 
GATGCTGCCA TTATACAGTT GAAGACCAAT GTTTCTCTTT GGAAGGAGCT GGAGTCAACT 
AAAGCTGTTA TTATGGGAGA AACTGCTGTT GTAGAAATAG ATACCTTTCC CCGAGGAGTA 
ATTTTAATAT ACCTAGTTAT AGCATTTTCA CCTTTTGGAT ACTTTTTGGC AATTCATATC 
GTAGCAGAAA AAGAAAAAAA AATAAAAGAA TTTTTAAAGA TAATGGGACT TCATGATACT 
GCCTTTTGGC TTTCCTGGGT TCTTCTATAT ACAAGTTTAA TTTTTCTTAT GTCCCTTCTT 
ATGGCAGTCA TTGCGACAGC TTCTTTGTTA TTTCCTCAAA GTAGCAGCAT TGTGATATTT 
CTGCTTTTTT TCCTTTATGG ATTATCATCT GTATTTTTTG CTTTAATGCT GACACCTCTT 
TTTAAAAAAT CAAAACATGT GGGAATAGTT GAATTTTTTG TTACTGTGGC TTTTGGATTT 
ATTGGCCTTA TGATAATCCT CATAGAAAGT TTTCCCAAAT CGTTAGTGTG GCTTTTCAGT 
CCTTTCTGTC ACTGTACTTT TGTGATTGGT ATTGCACAGG TCATGCATTT AGAAGATTTT 
AATGAAGGTG CTTCATTTTC AAATTTGACT GCAGGCCCAT ATCCTCTAAT TATTACAATT 
ATCATGCTCA CACTTAATAG TATATTCTAT GTCCTCTTGG CTGTCTATCT TGATCAAGTC 
ATTCCAGGGG AATTTGGCTT ACGGAGATCA TCTTTATATT TTCTGAAGCC TTCATATTGG 
TCAAAGAGCA AAAGAAATTA TGAGGAGTTA TCAGAGGGCA ATGTTAATGG AAATATTAGT 
TTTAGTGAAA TTATTGAGCC AGTTTCTTCA GAATTTGTAG GAAAAGAAGC CATAAGAATT 
AGTGGTATTC AGAAGACATA CAGAAAGAAG GGTGAAAATG TGGAGGCTTT GAGAAATTTG 
TCATTTGACA TATATGAGGG TCAGATTACT GCCTTACTTG GCCACAGTGG AACAGGAAAG 
AGTACATTGA TGAATATTCT TTGTGGACTC TGCCCACCTT CTGATGGGTT TGCATCTATA 
TATGGACACA GAGTCTCAGA AATAGATGAA ATGTTTGAAG CAAGAAAAAT GATTGGCATT 
TGTCCACAGT TAGATATACA CTTTGATGTT TTGACAGTAG AAGAAAATTT ATCAATTTTG 
GCTTCAATCA AAGGGATACC AGCCAACAAT ATAATACAAG AAGTGCAGAA GGTTTTACTA 
GATTTAGACA TGCAGACTAT CAAAGATAAC CAAGCTAAAA AATTAAGTGG TGGTCAAAAA 
AGAAAGCTGT CATTAGGAAT TGCTGTTCTT GGGAACCCAA AGATACTGCT GCTAGATGAA 
CCAACAGCTG GAATGGACCC CTGTTCTCGA CATATTGTAT GGAATCTTTT AAAATACAGA 
AAAGCCAATC GGGTGACAGT GTTCAGTACT CATTTCATGG ATGAAGCTGA CATTCTTGCA 
GATAGGAAAG CTGTGATATC ACAAGGAATG CTGAAATGTG TTGGTTCTTC AATGTTCCTC 
AAAAGTAAAT GGGGGATCGG CTACCGCCTG AGCATGTACA TAGACAAATA TTGTGCCACA 
GAATCTCTTT CTTCACTGGT TAAACAACAT ATACCTGGAG CTACTTTATT ACAACAGAAT 
GACCAACAAC TTGTGTATAG CTTGCCTTTC AAGGACATGG ACAAATTTTC AGGTTTGTTT 
TCTGCCCTAG ACAGTCATTC AAATTTGGGT GTCATTTCTT ATGGTGTTTC CATGACGACT 
TTGGAAGACG TATTTTTAAA GCTAGAAGTT GAAGCAGAAA TTGACCAAGC AGATTATAGT 
GTATTTACTC AGCAGCCACT GGAGGAAGAA ATGGATTCAA AATCTTTTGA TGAAATGGAA 
CAGAGCTTAC TTATTCTTTC TGAAACCAAG GCTGCTCTAG TGAGCACCAT GAGCCTTTGG 
AAACAACAGA TGTATACAAT AGCAAAGTTT CATTTCTTTA CCTTGAAACG TGAAAGTAAA 
TCAGTGAGAT CAGTGTTGCT TCTGCTTTTA ATTTTTTTCA CAGTTCAGAT TTTTATGTTT 
TTGGTTCATC ACTCTTTTAA AAATGCTGTG GTTCCCATCA AACTTGTTCC AGACTTATAT 
TTTCTAAAAC CTGGAGACAA ACCACATAAA TACAAAACAA GTCTGCTTCT TCAAAATTCT 
GCTGACTCAG ATATCAGTGA TCTTATTAGC TTTTTCACAA GCCAGAACAT AATGGTGACG 
ATGATTAATG ACAGTGACTA TGTATCCGTG GCTCCCCATA GTGCGGCTTT AAATGTGATG 
CATTCAGAAA AGGACTATGT TTTTGCAGCT GTTTTCAACA GTACTATGGT TTATTCTTTA 
CCTATATTAG TGAATATCAT TAGTAACTAC TATCTTTATC ATTTAAATGT GACTGAAACC 
ATCCAGATCT GGAGTACCCC ATTCTTTCAA GAAATTACTG ATATAGTTTT TAAAATTGAG 
CTGTATTTTC AAGCAGCTTT GCTTGGAATC ATTGTTACTG CAATGCCACC TTACTTTGCC 
ATGGAAAATG CAGAGAATCA TAAGATCAAA GCTTATACTC AACTTAAACT TTCAGGTCTT 
TTGCCATCTG CATATTGGAT TGGACAAGCT GTTGTTGATA TCCCCTTATT TTTTATCATT 
CTTATTTTGA TGCTAGGAAG CTTATTGGCA TTTCATTATG GATTATATTT TTATACTGTA 
AAGTTCCTTG CTGTGGTTTT TTGCCTTATT GGTTATGTTC CATCAGTTAT TCTGTTCACT 
TATATTGCTT CTTTCACCTT TAAGAAAATT TTAAATACCA AAGAATTTTG GTCATTTATC 
TATTCTGTGG CAGCGTTGGC TTGTATTGCA ATCACTGAAA TAACTTTCTT TATGGGATAC 
ACAATTGCAA CTATTCTTCA TTATGCCTTT TGTATCATCA TTCCAATCTA TCCACTTCTA 
GGTTGCCTGA TTTCTTTCAT AAAGATTTCT TGGAAGAATG TACGAAAAAA TGTGGACACC 
TATAATCCAT GGGATAGGCT TTCAGTAGCT GTTATATCGC CTTACCTGCA GTGTGTACTG 
TGGATTTTCC TCTTACAATA CTATGAGAAA AAATATGGAG GCAGATCAAT AAGAAAAGAT 
CCCTTTTTCA GAAACCTTTC AACGAAGTCT AAAAATAGGA AGCTTCCAGA ACCACCAGAC 
AATGAGGATG AAGATGAAGA TGTCAAAGCT GAAAGACTAA AGGTCAAAGA GCTGATGGGT 
TGCCAGTGTT GTGAGGAGAA ACCATCCATT ATGGTCAGCA ATTTGCATAA AGAATATGAT 
GACAAGAAAG ATTTTCTTCT TTCAAGAAAA GTAAAGAAAG TGGCAACTAA ATACATCTCT 
TTCTGTGTGA AAAAAGGAGA GATCTTAGGA CTATTGGGTC CAAATGGTGC TGGCAAAAGC 
ACAATTATTA ATATTCTGGT TGGTGATATT GAACCAACTT CAGGCCAGGT ATTTTTAGGA 
GATTATTCTT CAGAGACAAG TGAAGATGAT GATTCACTGA AGTGTATGGG TTACTGTCCT 
CAGATAAACC CTTTGTGGCC AGATACTACA TTGCAGGAAC ATTTTGAAAT TTATGGAGCT 
GTCAAAGGAA TGAGTGCAAG TGACATGAAA GAAGTCATAA GTCGAATAAC ACATGCACTT 
GATTTAAAAG AACATCTTCA GAAGACTGTA AAGAAACTAC CTGCAGGAAT CAAACGAAAG 
TTGTGTTTTG CTCTAAGTAT GCTAGGGAAT CCTCAGATTA CTTTGCTAGA TGAACCATCT 
ACAGGTATGG ATCCCAAAGC CAAACAGCAC ATGTGGCGAG CAATTCGAAC TGCATTTAAA 
AACAGAAAGC GGGCTGCTAT TCTGACCACT CACTATATGG AGGAGGCAGA GGCTGTCTGT 
GATCGAGTAG CTATCATGGT GTCTGGGCAG TTAAGATGTA TCGGAACAGT ACAACATCTA 
AAGAGTAAAT TTGGAAAAGG CTACTTTTTG GAAATTAAAT TGAAGGACTG GATAGAAAAC 
CTAGAAGTAG ACCGCCTTCA AAGAGAAATT CAGTATATTT TCCCAAATGC AAGCCGTCAG 
GAAAGTTTTT CTTCTATTTT GGCTTATAAA ATTCCTAAGG AAGATGTTCA GTCCCTTTCA 
CAATCTTTTT TTAAGCTGGA AGAAGCTAAA CATGCTTTTG CCATTGAAGA ATATAGCTTT 
TCTCAAGCAA CATTGGAACA GGTTTTTGTA GAACTCACTA AAGAACAAGA GGAGGAAGAT 
AATAGTTGTG GAACTTTAAA CAGCACACTT TGGTGGGAAC GAACACAAGA AGATAGAGTA 
GTATTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061142.2
CDS	1219..6147
Translation	MSTAIREVGVWRQTRTLLLKNYLIKCRTKKSSVQEILFPLFFLFWLILISMMHPNKKYEEVPNIELNPMDKFTLSNLILGYTPVTNITSSIMQKVSTDHLPDVIITEEYTNEKEMLTSSLSKPSNFVGVVFKDSMSYELRFFPDMIPVSSIYMDSRAGCSKSCEAAQYWSSGFTVLQASIDAAIIQLKTNVSLWKELESTKAVIMGETAVVEIDTFPRGVILIYLVIAFSPFGYFLAIHIVAEKEKKIKEFLKIMGLHDTAFWLSWVLLYTSLIFLMSLLMAVIATASLLFPQSSSIVIFLLFFLYGLSSVFFALMLTPLFKKSKHVGIVEFFVTVAFGFIGLMIILIESFPKSLVWLFSPFCHCTFVIGIAQVMHLEDFNEGASFSNLTAGPYPLIITIIMLTLNSIFYVLLAVYLDQVIPGEFGLRRSSLYFLKPSYWSKSKRNYEELSEGNVNGNISFSEIIEPVSSEFVGKEAIRISGIQKTYRKKGENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARKMIGICPQLDIHFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQTIKDNQAKKLSGGQKRKLSLGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVGSSMFLKSKWGIGYRLSMYIDKYCATESLSSLVKQHIPGATLLQQNDQQLVYSLPFKDMDKFSGLFSALDSHSNLGVISYGVSMTTLEDVFLKLEVEAEIDQADYSVFTQQPLEEEMDSKSFDEMEQSLLILSETKAALVSTMSLWKQQMYTIAKFHFFTLKRESKSVRSVLLLLLIFFTVQIFMFLVHHSFKNAVVPIKLVPDLYFLKPGDKPHKYKTSLLLQNSADSDISDLISFFTSQNIMVTMINDSDYVSVAPHSAALNVMHSEKDYVFAAVFNSTMVYSLPILVNIISNYYLYHLNVTETIQIWSTPFFQEITDIVFKIELYFQAALLGIIVTAMPPYFAMENAENHKIKAYTQLKLSGLLPSAYWIGQAVVDIPLFFIILILMLGSLLAFHYGLYFYTVKFLAVVFCLIGYVPSVILFTYIASFTFKKILNTKEFWSFIYSVAALACIAITEITFFMGYTIATILHYAFCIIIPIYPLLGCLISFIKISWKNVRKNVDTYNPWDRLSVAVISPYLQCVLWIFLLQYYEKKYGGRSIRKDPFFRNLSTKSKNRKLPEPPDNEDEDEDVKAERLKVKELMGCQCCEEKPSIMVSNLHKEYDDKKDFLLSRKVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDDSLKCMGYCPQINPLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSKFGKGYFLEIKLKDWIENLEVDRLQREIQYIFPNASRQESFSSILAYKIPKEDVQSLSQSFFKLEEAKHAFAIEEYSFSQATLEQVFVELTKEQEEEDNSCGTLNSTLWWERTQEDRVVF

Target ORF information:

RefSeq Version	NM_018672.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ATP binding cassette subfamily A member 5 (ABCA5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018672.4

ORF Insert Sequence:

ATGTCCACTG CAATTAGGGA GGTAGGAGTT TGGAGACAGA CCAGAACACT TCTACTGAAG 
AATTACTTAA TTAAATGCAG AACCAAAAAG AGTAGTGTTC AGGAAATTCT TTTTCCACTA 
TTTTTTTTAT TTTGGTTAAT ATTAATTAGC ATGATGCATC CAAATAAGAA ATATGAAGAA 
GTGCCTAATA TAGAACTCAA TCCTATGGAC AAGTTTACTC TTTCTAATCT AATTCTTGGA 
TATACTCCAG TGACTAATAT TACAAGCAGC ATCATGCAGA AAGTGTCTAC TGATCATCTA 
CCTGATGTCA TAATTACTGA AGAATATACA AATGAAAAAG AAATGTTAAC ATCCAGTCTC 
TCTAAGCCGA GCAACTTTGT AGGTGTGGTT TTCAAAGACT CCATGTCCTA TGAACTTCGT 
TTTTTTCCTG ATATGATTCC AGTATCTTCT ATTTATATGG ATTCAAGAGC TGGCTGTTCA 
AAATCATGTG AGGCTGCTCA GTACTGGTCC TCAGGTTTCA CAGTTTTACA AGCATCCATA 
GATGCTGCCA TTATACAGTT GAAGACCAAT GTTTCTCTTT GGAAGGAGCT GGAGTCAACT 
AAAGCTGTTA TTATGGGAGA AACTGCTGTT GTAGAAATAG ATACCTTTCC CCGAGGAGTA 
ATTTTAATAT ACCTAGTTAT AGCATTTTCA CCTTTTGGAT ACTTTTTGGC AATTCATATC 
GTAGCAGAAA AAGAAAAAAA AATAAAAGAA TTTTTAAAGA TAATGGGACT TCATGATACT 
GCCTTTTGGC TTTCCTGGGT TCTTCTATAT ACAAGTTTAA TTTTTCTTAT GTCCCTTCTT 
ATGGCAGTCA TTGCGACAGC TTCTTTGTTA TTTCCTCAAA GTAGCAGCAT TGTGATATTT 
CTGCTTTTTT TCCTTTATGG ATTATCATCT GTATTTTTTG CTTTAATGCT GACACCTCTT 
TTTAAAAAAT CAAAACATGT GGGAATAGTT GAATTTTTTG TTACTGTGGC TTTTGGATTT 
ATTGGCCTTA TGATAATCCT CATAGAAAGT TTTCCCAAAT CGTTAGTGTG GCTTTTCAGT 
CCTTTCTGTC ACTGTACTTT TGTGATTGGT ATTGCACAGG TCATGCATTT AGAAGATTTT 
AATGAAGGTG CTTCATTTTC AAATTTGACT GCAGGCCCAT ATCCTCTAAT TATTACAATT 
ATCATGCTCA CACTTAATAG TATATTCTAT GTCCTCTTGG CTGTCTATCT TGATCAAGTC 
ATTCCAGGGG AATTTGGCTT ACGGAGATCA TCTTTATATT TTCTGAAGCC TTCATATTGG 
TCAAAGAGCA AAAGAAATTA TGAGGAGTTA TCAGAGGGCA ATGTTAATGG AAATATTAGT 
TTTAGTGAAA TTATTGAGCC AGTTTCTTCA GAATTTGTAG GAAAAGAAGC CATAAGAATT 
AGTGGTATTC AGAAGACATA CAGAAAGAAG GGTGAAAATG TGGAGGCTTT GAGAAATTTG 
TCATTTGACA TATATGAGGG TCAGATTACT GCCTTACTTG GCCACAGTGG AACAGGAAAG 
AGTACATTGA TGAATATTCT TTGTGGACTC TGCCCACCTT CTGATGGGTT TGCATCTATA 
TATGGACACA GAGTCTCAGA AATAGATGAA ATGTTTGAAG CAAGAAAAAT GATTGGCATT 
TGTCCACAGT TAGATATACA CTTTGATGTT TTGACAGTAG AAGAAAATTT ATCAATTTTG 
GCTTCAATCA AAGGGATACC AGCCAACAAT ATAATACAAG AAGTGCAGAA GGTTTTACTA 
GATTTAGACA TGCAGACTAT CAAAGATAAC CAAGCTAAAA AATTAAGTGG TGGTCAAAAA 
AGAAAGCTGT CATTAGGAAT TGCTGTTCTT GGGAACCCAA AGATACTGCT GCTAGATGAA 
CCAACAGCTG GAATGGACCC CTGTTCTCGA CATATTGTAT GGAATCTTTT AAAATACAGA 
AAAGCCAATC GGGTGACAGT GTTCAGTACT CATTTCATGG ATGAAGCTGA CATTCTTGCA 
GATAGGAAAG CTGTGATATC ACAAGGAATG CTGAAATGTG TTGGTTCTTC AATGTTCCTC 
AAAAGTAAAT GGGGGATCGG CTACCGCCTG AGCATGTACA TAGACAAATA TTGTGCCACA 
GAATCTCTTT CTTCACTGGT TAAACAACAT ATACCTGGAG CTACTTTATT ACAACAGAAT 
GACCAACAAC TTGTGTATAG CTTGCCTTTC AAGGACATGG ACAAATTTTC AGGTTTGTTT 
TCTGCCCTAG ACAGTCATTC AAATTTGGGT GTCATTTCTT ATGGTGTTTC CATGACGACT 
TTGGAAGACG TATTTTTAAA GCTAGAAGTT GAAGCAGAAA TTGACCAAGC AGATTATAGT 
GTATTTACTC AGCAGCCACT GGAGGAAGAA ATGGATTCAA AATCTTTTGA TGAAATGGAA 
CAGAGCTTAC TTATTCTTTC TGAAACCAAG GCTGCTCTAG TGAGCACCAT GAGCCTTTGG 
AAACAACAGA TGTATACAAT AGCAAAGTTT CATTTCTTTA CCTTGAAACG TGAAAGTAAA 
TCAGTGAGAT CAGTGTTGCT TCTGCTTTTA ATTTTTTTCA CAGTTCAGAT TTTTATGTTT 
TTGGTTCATC ACTCTTTTAA AAATGCTGTG GTTCCCATCA AACTTGTTCC AGACTTATAT 
TTTCTAAAAC CTGGAGACAA ACCACATAAA TACAAAACAA GTCTGCTTCT TCAAAATTCT 
GCTGACTCAG ATATCAGTGA TCTTATTAGC TTTTTCACAA GCCAGAACAT AATGGTGACG 
ATGATTAATG ACAGTGACTA TGTATCCGTG GCTCCCCATA GTGCGGCTTT AAATGTGATG 
CATTCAGAAA AGGACTATGT TTTTGCAGCT GTTTTCAACA GTACTATGGT TTATTCTTTA 
CCTATATTAG TGAATATCAT TAGTAACTAC TATCTTTATC ATTTAAATGT GACTGAAACC 
ATCCAGATCT GGAGTACCCC ATTCTTTCAA GAAATTACTG ATATAGTTTT TAAAATTGAG 
CTGTATTTTC AAGCAGCTTT GCTTGGAATC ATTGTTACTG CAATGCCACC TTACTTTGCC 
ATGGAAAATG CAGAGAATCA TAAGATCAAA GCTTATACTC AACTTAAACT TTCAGGTCTT 
TTGCCATCTG CATATTGGAT TGGACAAGCT GTTGTTGATA TCCCCTTATT TTTTATCATT 
CTTATTTTGA TGCTAGGAAG CTTATTGGCA TTTCATTATG GATTATATTT TTATACTGTA 
AAGTTCCTTG CTGTGGTTTT TTGCCTTATT GGTTATGTTC CATCAGTTAT TCTGTTCACT 
TATATTGCTT CTTTCACCTT TAAGAAAATT TTAAATACCA AAGAATTTTG GTCATTTATC 
TATTCTGTGG CAGCGTTGGC TTGTATTGCA ATCACTGAAA TAACTTTCTT TATGGGATAC 
ACAATTGCAA CTATTCTTCA TTATGCCTTT TGTATCATCA TTCCAATCTA TCCACTTCTA 
GGTTGCCTGA TTTCTTTCAT AAAGATTTCT TGGAAGAATG TACGAAAAAA TGTGGACACC 
TATAATCCAT GGGATAGGCT TTCAGTAGCT GTTATATCGC CTTACCTGCA GTGTGTACTG 
TGGATTTTCC TCTTACAATA CTATGAGAAA AAATATGGAG GCAGATCAAT AAGAAAAGAT 
CCCTTTTTCA GAAACCTTTC AACGAAGTCT AAAAATAGGA AGCTTCCAGA ACCACCAGAC 
AATGAGGATG AAGATGAAGA TGTCAAAGCT GAAAGACTAA AGGTCAAAGA GCTGATGGGT 
TGCCAGTGTT GTGAGGAGAA ACCATCCATT ATGGTCAGCA ATTTGCATAA AGAATATGAT 
GACAAGAAAG ATTTTCTTCT TTCAAGAAAA GTAAAGAAAG TGGCAACTAA ATACATCTCT 
TTCTGTGTGA AAAAAGGAGA GATCTTAGGA CTATTGGGTC CAAATGGTGC TGGCAAAAGC 
ACAATTATTA ATATTCTGGT TGGTGATATT GAACCAACTT CAGGCCAGGT ATTTTTAGGA 
GATTATTCTT CAGAGACAAG TGAAGATGAT GATTCACTGA AGTGTATGGG TTACTGTCCT 
CAGATAAACC CTTTGTGGCC AGATACTACA TTGCAGGAAC ATTTTGAAAT TTATGGAGCT 
GTCAAAGGAA TGAGTGCAAG TGACATGAAA GAAGTCATAA GTCGAATAAC ACATGCACTT 
GATTTAAAAG AACATCTTCA GAAGACTGTA AAGAAACTAC CTGCAGGAAT CAAACGAAAG 
TTGTGTTTTG CTCTAAGTAT GCTAGGGAAT CCTCAGATTA CTTTGCTAGA TGAACCATCT 
ACAGGTATGG ATCCCAAAGC CAAACAGCAC ATGTGGCGAG CAATTCGAAC TGCATTTAAA 
AACAGAAAGC GGGCTGCTAT TCTGACCACT CACTATATGG AGGAGGCAGA GGCTGTCTGT 
GATCGAGTAG CTATCATGGT GTCTGGGCAG TTAAGATGTA TCGGAACAGT ACAACATCTA 
AAGAGTAAAT TTGGAAAAGG CTACTTTTTG GAAATTAAAT TGAAGGACTG GATAGAAAAC 
CTAGAAGTAG ACCGCCTTCA AAGAGAAATT CAGTATATTT TCCCAAATGC AAGCCGTCAG 
GAAAGTTTTT CTTCTATTTT GGCTTATAAA ATTCCTAAGG AAGATGTTCA GTCCCTTTCA 
CAATCTTTTT TTAAGCTGGA AGAAGCTAAA CATGCTTTTG CCATTGAAGA ATATAGCTTT 
TCTCAAGCAA CATTGGAACA GGTTTTTGTA GAACTCACTA AAGAACAAGA GGAGGAAGAT 
AATAGTTGTG GAACTTTAAA CAGCACACTT TGGTGGGAAC GAACACAAGA AGATAGAGTA 
GTATTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ABCA5 ( NM_172232.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_758424.1 Homo sapiens ATP binding cassette subfamily A member 5 (ABCA5), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu23763
Clone ID Related Accession (Same CDS sequence)	NM_018672.4 , NM_172232.3 , NM_172232.4
Accession Version	NM_172232.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4929bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-27
Organism	Homo sapiens(human)
Product	ATP-binding cassette sub-family A member 5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB096625.1, AJ275973.3, AC115085.4, AK058170.1, AC005495.2 and KF456324.1. This sequence is a reference standard in the RefSeqGene project. On Jan 17, 2014 this sequence version replaced NM_172232.2. Transcript Variant: This variant (2) represents the shorter transcript variant. It contains a distinct 5' UTR compared to transcript variant 1, but encodes the same protein. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The extent of this RefSeq transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.49939.1, SRR1803617.206054.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCACTG CAATTAGGGA GGTAGGAGTT TGGAGACAGA CCAGAACACT TCTACTGAAG 
AATTACTTAA TTAAATGCAG AACCAAAAAG AGTAGTGTTC AGGAAATTCT TTTTCCACTA 
TTTTTTTTAT TTTGGTTAAT ATTAATTAGC ATGATGCATC CAAATAAGAA ATATGAAGAA 
GTGCCTAATA TAGAACTCAA TCCTATGGAC AAGTTTACTC TTTCTAATCT AATTCTTGGA 
TATACTCCAG TGACTAATAT TACAAGCAGC ATCATGCAGA AAGTGTCTAC TGATCATCTA 
CCTGATGTCA TAATTACTGA AGAATATACA AATGAAAAAG AAATGTTAAC ATCCAGTCTC 
TCTAAGCCGA GCAACTTTGT AGGTGTGGTT TTCAAAGACT CCATGTCCTA TGAACTTCGT 
TTTTTTCCTG ATATGATTCC AGTATCTTCT ATTTATATGG ATTCAAGAGC TGGCTGTTCA 
AAATCATGTG AGGCTGCTCA GTACTGGTCC TCAGGTTTCA CAGTTTTACA AGCATCCATA 
GATGCTGCCA TTATACAGTT GAAGACCAAT GTTTCTCTTT GGAAGGAGCT GGAGTCAACT 
AAAGCTGTTA TTATGGGAGA AACTGCTGTT GTAGAAATAG ATACCTTTCC CCGAGGAGTA 
ATTTTAATAT ACCTAGTTAT AGCATTTTCA CCTTTTGGAT ACTTTTTGGC AATTCATATC 
GTAGCAGAAA AAGAAAAAAA AATAAAAGAA TTTTTAAAGA TAATGGGACT TCATGATACT 
GCCTTTTGGC TTTCCTGGGT TCTTCTATAT ACAAGTTTAA TTTTTCTTAT GTCCCTTCTT 
ATGGCAGTCA TTGCGACAGC TTCTTTGTTA TTTCCTCAAA GTAGCAGCAT TGTGATATTT 
CTGCTTTTTT TCCTTTATGG ATTATCATCT GTATTTTTTG CTTTAATGCT GACACCTCTT 
TTTAAAAAAT CAAAACATGT GGGAATAGTT GAATTTTTTG TTACTGTGGC TTTTGGATTT 
ATTGGCCTTA TGATAATCCT CATAGAAAGT TTTCCCAAAT CGTTAGTGTG GCTTTTCAGT 
CCTTTCTGTC ACTGTACTTT TGTGATTGGT ATTGCACAGG TCATGCATTT AGAAGATTTT 
AATGAAGGTG CTTCATTTTC AAATTTGACT GCAGGCCCAT ATCCTCTAAT TATTACAATT 
ATCATGCTCA CACTTAATAG TATATTCTAT GTCCTCTTGG CTGTCTATCT TGATCAAGTC 
ATTCCAGGGG AATTTGGCTT ACGGAGATCA TCTTTATATT TTCTGAAGCC TTCATATTGG 
TCAAAGAGCA AAAGAAATTA TGAGGAGTTA TCAGAGGGCA ATGTTAATGG AAATATTAGT 
TTTAGTGAAA TTATTGAGCC AGTTTCTTCA GAATTTGTAG GAAAAGAAGC CATAAGAATT 
AGTGGTATTC AGAAGACATA CAGAAAGAAG GGTGAAAATG TGGAGGCTTT GAGAAATTTG 
TCATTTGACA TATATGAGGG TCAGATTACT GCCTTACTTG GCCACAGTGG AACAGGAAAG 
AGTACATTGA TGAATATTCT TTGTGGACTC TGCCCACCTT CTGATGGGTT TGCATCTATA 
TATGGACACA GAGTCTCAGA AATAGATGAA ATGTTTGAAG CAAGAAAAAT GATTGGCATT 
TGTCCACAGT TAGATATACA CTTTGATGTT TTGACAGTAG AAGAAAATTT ATCAATTTTG 
GCTTCAATCA AAGGGATACC AGCCAACAAT ATAATACAAG AAGTGCAGAA GGTTTTACTA 
GATTTAGACA TGCAGACTAT CAAAGATAAC CAAGCTAAAA AATTAAGTGG TGGTCAAAAA 
AGAAAGCTGT CATTAGGAAT TGCTGTTCTT GGGAACCCAA AGATACTGCT GCTAGATGAA 
CCAACAGCTG GAATGGACCC CTGTTCTCGA CATATTGTAT GGAATCTTTT AAAATACAGA 
AAAGCCAATC GGGTGACAGT GTTCAGTACT CATTTCATGG ATGAAGCTGA CATTCTTGCA 
GATAGGAAAG CTGTGATATC ACAAGGAATG CTGAAATGTG TTGGTTCTTC AATGTTCCTC 
AAAAGTAAAT GGGGGATCGG CTACCGCCTG AGCATGTACA TAGACAAATA TTGTGCCACA 
GAATCTCTTT CTTCACTGGT TAAACAACAT ATACCTGGAG CTACTTTATT ACAACAGAAT 
GACCAACAAC TTGTGTATAG CTTGCCTTTC AAGGACATGG ACAAATTTTC AGGTTTGTTT 
TCTGCCCTAG ACAGTCATTC AAATTTGGGT GTCATTTCTT ATGGTGTTTC CATGACGACT 
TTGGAAGACG TATTTTTAAA GCTAGAAGTT GAAGCAGAAA TTGACCAAGC AGATTATAGT 
GTATTTACTC AGCAGCCACT GGAGGAAGAA ATGGATTCAA AATCTTTTGA TGAAATGGAA 
CAGAGCTTAC TTATTCTTTC TGAAACCAAG GCTGCTCTAG TGAGCACCAT GAGCCTTTGG 
AAACAACAGA TGTATACAAT AGCAAAGTTT CATTTCTTTA CCTTGAAACG TGAAAGTAAA 
TCAGTGAGAT CAGTGTTGCT TCTGCTTTTA ATTTTTTTCA CAGTTCAGAT TTTTATGTTT 
TTGGTTCATC ACTCTTTTAA AAATGCTGTG GTTCCCATCA AACTTGTTCC AGACTTATAT 
TTTCTAAAAC CTGGAGACAA ACCACATAAA TACAAAACAA GTCTGCTTCT TCAAAATTCT 
GCTGACTCAG ATATCAGTGA TCTTATTAGC TTTTTCACAA GCCAGAACAT AATGGTGACG 
ATGATTAATG ACAGTGACTA TGTATCCGTG GCTCCCCATA GTGCGGCTTT AAATGTGATG 
CATTCAGAAA AGGACTATGT TTTTGCAGCT GTTTTCAACA GTACTATGGT TTATTCTTTA 
CCTATATTAG TGAATATCAT TAGTAACTAC TATCTTTATC ATTTAAATGT GACTGAAACC 
ATCCAGATCT GGAGTACCCC ATTCTTTCAA GAAATTACTG ATATAGTTTT TAAAATTGAG 
CTGTATTTTC AAGCAGCTTT GCTTGGAATC ATTGTTACTG CAATGCCACC TTACTTTGCC 
ATGGAAAATG CAGAGAATCA TAAGATCAAA GCTTATACTC AACTTAAACT TTCAGGTCTT 
TTGCCATCTG CATATTGGAT TGGACAAGCT GTTGTTGATA TCCCCTTATT TTTTATCATT 
CTTATTTTGA TGCTAGGAAG CTTATTGGCA TTTCATTATG GATTATATTT TTATACTGTA 
AAGTTCCTTG CTGTGGTTTT TTGCCTTATT GGTTATGTTC CATCAGTTAT TCTGTTCACT 
TATATTGCTT CTTTCACCTT TAAGAAAATT TTAAATACCA AAGAATTTTG GTCATTTATC 
TATTCTGTGG CAGCGTTGGC TTGTATTGCA ATCACTGAAA TAACTTTCTT TATGGGATAC 
ACAATTGCAA CTATTCTTCA TTATGCCTTT TGTATCATCA TTCCAATCTA TCCACTTCTA 
GGTTGCCTGA TTTCTTTCAT AAAGATTTCT TGGAAGAATG TACGAAAAAA TGTGGACACC 
TATAATCCAT GGGATAGGCT TTCAGTAGCT GTTATATCGC CTTACCTGCA GTGTGTACTG 
TGGATTTTCC TCTTACAATA CTATGAGAAA AAATATGGAG GCAGATCAAT AAGAAAAGAT 
CCCTTTTTCA GAAACCTTTC AACGAAGTCT AAAAATAGGA AGCTTCCAGA ACCACCAGAC 
AATGAGGATG AAGATGAAGA TGTCAAAGCT GAAAGACTAA AGGTCAAAGA GCTGATGGGT 
TGCCAGTGTT GTGAGGAGAA ACCATCCATT ATGGTCAGCA ATTTGCATAA AGAATATGAT 
GACAAGAAAG ATTTTCTTCT TTCAAGAAAA GTAAAGAAAG TGGCAACTAA ATACATCTCT 
TTCTGTGTGA AAAAAGGAGA GATCTTAGGA CTATTGGGTC CAAATGGTGC TGGCAAAAGC 
ACAATTATTA ATATTCTGGT TGGTGATATT GAACCAACTT CAGGCCAGGT ATTTTTAGGA 
GATTATTCTT CAGAGACAAG TGAAGATGAT GATTCACTGA AGTGTATGGG TTACTGTCCT 
CAGATAAACC CTTTGTGGCC AGATACTACA TTGCAGGAAC ATTTTGAAAT TTATGGAGCT 
GTCAAAGGAA TGAGTGCAAG TGACATGAAA GAAGTCATAA GTCGAATAAC ACATGCACTT 
GATTTAAAAG AACATCTTCA GAAGACTGTA AAGAAACTAC CTGCAGGAAT CAAACGAAAG 
TTGTGTTTTG CTCTAAGTAT GCTAGGGAAT CCTCAGATTA CTTTGCTAGA TGAACCATCT 
ACAGGTATGG ATCCCAAAGC CAAACAGCAC ATGTGGCGAG CAATTCGAAC TGCATTTAAA 
AACAGAAAGC GGGCTGCTAT TCTGACCACT CACTATATGG AGGAGGCAGA GGCTGTCTGT 
GATCGAGTAG CTATCATGGT GTCTGGGCAG TTAAGATGTA TCGGAACAGT ACAACATCTA 
AAGAGTAAAT TTGGAAAAGG CTACTTTTTG GAAATTAAAT TGAAGGACTG GATAGAAAAC 
CTAGAAGTAG ACCGCCTTCA AAGAGAAATT CAGTATATTT TCCCAAATGC AAGCCGTCAG 
GAAAGTTTTT CTTCTATTTT GGCTTATAAA ATTCCTAAGG AAGATGTTCA GTCCCTTTCA 
CAATCTTTTT TTAAGCTGGA AGAAGCTAAA CATGCTTTTG CCATTGAAGA ATATAGCTTT 
TCTCAAGCAA CATTGGAACA GGTTTTTGTA GAACTCACTA AAGAACAAGA GGAGGAAGAT 
AATAGTTGTG GAACTTTAAA CAGCACACTT TGGTGGGAAC GAACACAAGA AGATAGAGTA 
GTATTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_758424.1
CDS	147..5075
Translation	MSTAIREVGVWRQTRTLLLKNYLIKCRTKKSSVQEILFPLFFLFWLILISMMHPNKKYEEVPNIELNPMDKFTLSNLILGYTPVTNITSSIMQKVSTDHLPDVIITEEYTNEKEMLTSSLSKPSNFVGVVFKDSMSYELRFFPDMIPVSSIYMDSRAGCSKSCEAAQYWSSGFTVLQASIDAAIIQLKTNVSLWKELESTKAVIMGETAVVEIDTFPRGVILIYLVIAFSPFGYFLAIHIVAEKEKKIKEFLKIMGLHDTAFWLSWVLLYTSLIFLMSLLMAVIATASLLFPQSSSIVIFLLFFLYGLSSVFFALMLTPLFKKSKHVGIVEFFVTVAFGFIGLMIILIESFPKSLVWLFSPFCHCTFVIGIAQVMHLEDFNEGASFSNLTAGPYPLIITIIMLTLNSIFYVLLAVYLDQVIPGEFGLRRSSLYFLKPSYWSKSKRNYEELSEGNVNGNISFSEIIEPVSSEFVGKEAIRISGIQKTYRKKGENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARKMIGICPQLDIHFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQTIKDNQAKKLSGGQKRKLSLGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVGSSMFLKSKWGIGYRLSMYIDKYCATESLSSLVKQHIPGATLLQQNDQQLVYSLPFKDMDKFSGLFSALDSHSNLGVISYGVSMTTLEDVFLKLEVEAEIDQADYSVFTQQPLEEEMDSKSFDEMEQSLLILSETKAALVSTMSLWKQQMYTIAKFHFFTLKRESKSVRSVLLLLLIFFTVQIFMFLVHHSFKNAVVPIKLVPDLYFLKPGDKPHKYKTSLLLQNSADSDISDLISFFTSQNIMVTMINDSDYVSVAPHSAALNVMHSEKDYVFAAVFNSTMVYSLPILVNIISNYYLYHLNVTETIQIWSTPFFQEITDIVFKIELYFQAALLGIIVTAMPPYFAMENAENHKIKAYTQLKLSGLLPSAYWIGQAVVDIPLFFIILILMLGSLLAFHYGLYFYTVKFLAVVFCLIGYVPSVILFTYIASFTFKKILNTKEFWSFIYSVAALACIAITEITFFMGYTIATILHYAFCIIIPIYPLLGCLISFIKISWKNVRKNVDTYNPWDRLSVAVISPYLQCVLWIFLLQYYEKKYGGRSIRKDPFFRNLSTKSKNRKLPEPPDNEDEDEDVKAERLKVKELMGCQCCEEKPSIMVSNLHKEYDDKKDFLLSRKVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDDSLKCMGYCPQINPLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSKFGKGYFLEIKLKDWIENLEVDRLQREIQYIFPNASRQESFSSILAYKIPKEDVQSLSQSFFKLEEAKHAFAIEEYSFSQATLEQVFVELTKEQEEEDNSCGTLNSTLWWERTQEDRVVF

Target ORF information:

RefSeq Version	NM_172232.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ATP binding cassette subfamily A member 5 (ABCA5), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_172232.3

ORF Insert Sequence:

ATGTCCACTG CAATTAGGGA GGTAGGAGTT TGGAGACAGA CCAGAACACT TCTACTGAAG 
AATTACTTAA TTAAATGCAG AACCAAAAAG AGTAGTGTTC AGGAAATTCT TTTTCCACTA 
TTTTTTTTAT TTTGGTTAAT ATTAATTAGC ATGATGCATC CAAATAAGAA ATATGAAGAA 
GTGCCTAATA TAGAACTCAA TCCTATGGAC AAGTTTACTC TTTCTAATCT AATTCTTGGA 
TATACTCCAG TGACTAATAT TACAAGCAGC ATCATGCAGA AAGTGTCTAC TGATCATCTA 
CCTGATGTCA TAATTACTGA AGAATATACA AATGAAAAAG AAATGTTAAC ATCCAGTCTC 
TCTAAGCCGA GCAACTTTGT AGGTGTGGTT TTCAAAGACT CCATGTCCTA TGAACTTCGT 
TTTTTTCCTG ATATGATTCC AGTATCTTCT ATTTATATGG ATTCAAGAGC TGGCTGTTCA 
AAATCATGTG AGGCTGCTCA GTACTGGTCC TCAGGTTTCA CAGTTTTACA AGCATCCATA 
GATGCTGCCA TTATACAGTT GAAGACCAAT GTTTCTCTTT GGAAGGAGCT GGAGTCAACT 
AAAGCTGTTA TTATGGGAGA AACTGCTGTT GTAGAAATAG ATACCTTTCC CCGAGGAGTA 
ATTTTAATAT ACCTAGTTAT AGCATTTTCA CCTTTTGGAT ACTTTTTGGC AATTCATATC 
GTAGCAGAAA AAGAAAAAAA AATAAAAGAA TTTTTAAAGA TAATGGGACT TCATGATACT 
GCCTTTTGGC TTTCCTGGGT TCTTCTATAT ACAAGTTTAA TTTTTCTTAT GTCCCTTCTT 
ATGGCAGTCA TTGCGACAGC TTCTTTGTTA TTTCCTCAAA GTAGCAGCAT TGTGATATTT 
CTGCTTTTTT TCCTTTATGG ATTATCATCT GTATTTTTTG CTTTAATGCT GACACCTCTT 
TTTAAAAAAT CAAAACATGT GGGAATAGTT GAATTTTTTG TTACTGTGGC TTTTGGATTT 
ATTGGCCTTA TGATAATCCT CATAGAAAGT TTTCCCAAAT CGTTAGTGTG GCTTTTCAGT 
CCTTTCTGTC ACTGTACTTT TGTGATTGGT ATTGCACAGG TCATGCATTT AGAAGATTTT 
AATGAAGGTG CTTCATTTTC AAATTTGACT GCAGGCCCAT ATCCTCTAAT TATTACAATT 
ATCATGCTCA CACTTAATAG TATATTCTAT GTCCTCTTGG CTGTCTATCT TGATCAAGTC 
ATTCCAGGGG AATTTGGCTT ACGGAGATCA TCTTTATATT TTCTGAAGCC TTCATATTGG 
TCAAAGAGCA AAAGAAATTA TGAGGAGTTA TCAGAGGGCA ATGTTAATGG AAATATTAGT 
TTTAGTGAAA TTATTGAGCC AGTTTCTTCA GAATTTGTAG GAAAAGAAGC CATAAGAATT 
AGTGGTATTC AGAAGACATA CAGAAAGAAG GGTGAAAATG TGGAGGCTTT GAGAAATTTG 
TCATTTGACA TATATGAGGG TCAGATTACT GCCTTACTTG GCCACAGTGG AACAGGAAAG 
AGTACATTGA TGAATATTCT TTGTGGACTC TGCCCACCTT CTGATGGGTT TGCATCTATA 
TATGGACACA GAGTCTCAGA AATAGATGAA ATGTTTGAAG CAAGAAAAAT GATTGGCATT 
TGTCCACAGT TAGATATACA CTTTGATGTT TTGACAGTAG AAGAAAATTT ATCAATTTTG 
GCTTCAATCA AAGGGATACC AGCCAACAAT ATAATACAAG AAGTGCAGAA GGTTTTACTA 
GATTTAGACA TGCAGACTAT CAAAGATAAC CAAGCTAAAA AATTAAGTGG TGGTCAAAAA 
AGAAAGCTGT CATTAGGAAT TGCTGTTCTT GGGAACCCAA AGATACTGCT GCTAGATGAA 
CCAACAGCTG GAATGGACCC CTGTTCTCGA CATATTGTAT GGAATCTTTT AAAATACAGA 
AAAGCCAATC GGGTGACAGT GTTCAGTACT CATTTCATGG ATGAAGCTGA CATTCTTGCA 
GATAGGAAAG CTGTGATATC ACAAGGAATG CTGAAATGTG TTGGTTCTTC AATGTTCCTC 
AAAAGTAAAT GGGGGATCGG CTACCGCCTG AGCATGTACA TAGACAAATA TTGTGCCACA 
GAATCTCTTT CTTCACTGGT TAAACAACAT ATACCTGGAG CTACTTTATT ACAACAGAAT 
GACCAACAAC TTGTGTATAG CTTGCCTTTC AAGGACATGG ACAAATTTTC AGGTTTGTTT 
TCTGCCCTAG ACAGTCATTC AAATTTGGGT GTCATTTCTT ATGGTGTTTC CATGACGACT 
TTGGAAGACG TATTTTTAAA GCTAGAAGTT GAAGCAGAAA TTGACCAAGC AGATTATAGT 
GTATTTACTC AGCAGCCACT GGAGGAAGAA ATGGATTCAA AATCTTTTGA TGAAATGGAA 
CAGAGCTTAC TTATTCTTTC TGAAACCAAG GCTGCTCTAG TGAGCACCAT GAGCCTTTGG 
AAACAACAGA TGTATACAAT AGCAAAGTTT CATTTCTTTA CCTTGAAACG TGAAAGTAAA 
TCAGTGAGAT CAGTGTTGCT TCTGCTTTTA ATTTTTTTCA CAGTTCAGAT TTTTATGTTT 
TTGGTTCATC ACTCTTTTAA AAATGCTGTG GTTCCCATCA AACTTGTTCC AGACTTATAT 
TTTCTAAAAC CTGGAGACAA ACCACATAAA TACAAAACAA GTCTGCTTCT TCAAAATTCT 
GCTGACTCAG ATATCAGTGA TCTTATTAGC TTTTTCACAA GCCAGAACAT AATGGTGACG 
ATGATTAATG ACAGTGACTA TGTATCCGTG GCTCCCCATA GTGCGGCTTT AAATGTGATG 
CATTCAGAAA AGGACTATGT TTTTGCAGCT GTTTTCAACA GTACTATGGT TTATTCTTTA 
CCTATATTAG TGAATATCAT TAGTAACTAC TATCTTTATC ATTTAAATGT GACTGAAACC 
ATCCAGATCT GGAGTACCCC ATTCTTTCAA GAAATTACTG ATATAGTTTT TAAAATTGAG 
CTGTATTTTC AAGCAGCTTT GCTTGGAATC ATTGTTACTG CAATGCCACC TTACTTTGCC 
ATGGAAAATG CAGAGAATCA TAAGATCAAA GCTTATACTC AACTTAAACT TTCAGGTCTT 
TTGCCATCTG CATATTGGAT TGGACAAGCT GTTGTTGATA TCCCCTTATT TTTTATCATT 
CTTATTTTGA TGCTAGGAAG CTTATTGGCA TTTCATTATG GATTATATTT TTATACTGTA 
AAGTTCCTTG CTGTGGTTTT TTGCCTTATT GGTTATGTTC CATCAGTTAT TCTGTTCACT 
TATATTGCTT CTTTCACCTT TAAGAAAATT TTAAATACCA AAGAATTTTG GTCATTTATC 
TATTCTGTGG CAGCGTTGGC TTGTATTGCA ATCACTGAAA TAACTTTCTT TATGGGATAC 
ACAATTGCAA CTATTCTTCA TTATGCCTTT TGTATCATCA TTCCAATCTA TCCACTTCTA 
GGTTGCCTGA TTTCTTTCAT AAAGATTTCT TGGAAGAATG TACGAAAAAA TGTGGACACC 
TATAATCCAT GGGATAGGCT TTCAGTAGCT GTTATATCGC CTTACCTGCA GTGTGTACTG 
TGGATTTTCC TCTTACAATA CTATGAGAAA AAATATGGAG GCAGATCAAT AAGAAAAGAT 
CCCTTTTTCA GAAACCTTTC AACGAAGTCT AAAAATAGGA AGCTTCCAGA ACCACCAGAC 
AATGAGGATG AAGATGAAGA TGTCAAAGCT GAAAGACTAA AGGTCAAAGA GCTGATGGGT 
TGCCAGTGTT GTGAGGAGAA ACCATCCATT ATGGTCAGCA ATTTGCATAA AGAATATGAT 
GACAAGAAAG ATTTTCTTCT TTCAAGAAAA GTAAAGAAAG TGGCAACTAA ATACATCTCT 
TTCTGTGTGA AAAAAGGAGA GATCTTAGGA CTATTGGGTC CAAATGGTGC TGGCAAAAGC 
ACAATTATTA ATATTCTGGT TGGTGATATT GAACCAACTT CAGGCCAGGT ATTTTTAGGA 
GATTATTCTT CAGAGACAAG TGAAGATGAT GATTCACTGA AGTGTATGGG TTACTGTCCT 
CAGATAAACC CTTTGTGGCC AGATACTACA TTGCAGGAAC ATTTTGAAAT TTATGGAGCT 
GTCAAAGGAA TGAGTGCAAG TGACATGAAA GAAGTCATAA GTCGAATAAC ACATGCACTT 
GATTTAAAAG AACATCTTCA GAAGACTGTA AAGAAACTAC CTGCAGGAAT CAAACGAAAG 
TTGTGTTTTG CTCTAAGTAT GCTAGGGAAT CCTCAGATTA CTTTGCTAGA TGAACCATCT 
ACAGGTATGG ATCCCAAAGC CAAACAGCAC ATGTGGCGAG CAATTCGAAC TGCATTTAAA 
AACAGAAAGC GGGCTGCTAT TCTGACCACT CACTATATGG AGGAGGCAGA GGCTGTCTGT 
GATCGAGTAG CTATCATGGT GTCTGGGCAG TTAAGATGTA TCGGAACAGT ACAACATCTA 
AAGAGTAAAT TTGGAAAAGG CTACTTTTTG GAAATTAAAT TGAAGGACTG GATAGAAAAC 
CTAGAAGTAG ACCGCCTTCA AAGAGAAATT CAGTATATTT TCCCAAATGC AAGCCGTCAG 
GAAAGTTTTT CTTCTATTTT GGCTTATAAA ATTCCTAAGG AAGATGTTCA GTCCCTTTCA 
CAATCTTTTT TTAAGCTGGA AGAAGCTAAA CATGCTTTTG CCATTGAAGA ATATAGCTTT 
TCTCAAGCAA CATTGGAACA GGTTTTTGTA GAACTCACTA AAGAACAAGA GGAGGAAGAT 
AATAGTTGTG GAACTTTAAA CAGCACACTT TGGTGGGAAC GAACACAAGA AGATAGAGTA 
GTATTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ABCA5 ( NM_172232.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_758424.1 Homo sapiens ATP binding cassette subfamily A member 5 (ABCA5), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu23763
Clone ID Related Accession (Same CDS sequence)	NM_018672.4 , NM_172232.3 , NM_172232.4
Accession Version	NM_172232.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4929bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	ATP-binding cassette sub-family A member 5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB096625.1, AJ275973.3, AC115085.4, AK058170.1, AC005495.2 and KF456324.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_172232.3. Transcript Variant: This variant (2) represents the shorter transcript variant. It contains a distinct 5' UTR compared to transcript variant 1, but encodes the same protein. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The extent of this RefSeq transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.49939.1, SRR1803617.206054.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000392676.8/ ENSP00000376443.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCCACTG CAATTAGGGA GGTAGGAGTT TGGAGACAGA CCAGAACACT TCTACTGAAG 
AATTACTTAA TTAAATGCAG AACCAAAAAG AGTAGTGTTC AGGAAATTCT TTTTCCACTA 
TTTTTTTTAT TTTGGTTAAT ATTAATTAGC ATGATGCATC CAAATAAGAA ATATGAAGAA 
GTGCCTAATA TAGAACTCAA TCCTATGGAC AAGTTTACTC TTTCTAATCT AATTCTTGGA 
TATACTCCAG TGACTAATAT TACAAGCAGC ATCATGCAGA AAGTGTCTAC TGATCATCTA 
CCTGATGTCA TAATTACTGA AGAATATACA AATGAAAAAG AAATGTTAAC ATCCAGTCTC 
TCTAAGCCGA GCAACTTTGT AGGTGTGGTT TTCAAAGACT CCATGTCCTA TGAACTTCGT 
TTTTTTCCTG ATATGATTCC AGTATCTTCT ATTTATATGG ATTCAAGAGC TGGCTGTTCA 
AAATCATGTG AGGCTGCTCA GTACTGGTCC TCAGGTTTCA CAGTTTTACA AGCATCCATA 
GATGCTGCCA TTATACAGTT GAAGACCAAT GTTTCTCTTT GGAAGGAGCT GGAGTCAACT 
AAAGCTGTTA TTATGGGAGA AACTGCTGTT GTAGAAATAG ATACCTTTCC CCGAGGAGTA 
ATTTTAATAT ACCTAGTTAT AGCATTTTCA CCTTTTGGAT ACTTTTTGGC AATTCATATC 
GTAGCAGAAA AAGAAAAAAA AATAAAAGAA TTTTTAAAGA TAATGGGACT TCATGATACT 
GCCTTTTGGC TTTCCTGGGT TCTTCTATAT ACAAGTTTAA TTTTTCTTAT GTCCCTTCTT 
ATGGCAGTCA TTGCGACAGC TTCTTTGTTA TTTCCTCAAA GTAGCAGCAT TGTGATATTT 
CTGCTTTTTT TCCTTTATGG ATTATCATCT GTATTTTTTG CTTTAATGCT GACACCTCTT 
TTTAAAAAAT CAAAACATGT GGGAATAGTT GAATTTTTTG TTACTGTGGC TTTTGGATTT 
ATTGGCCTTA TGATAATCCT CATAGAAAGT TTTCCCAAAT CGTTAGTGTG GCTTTTCAGT 
CCTTTCTGTC ACTGTACTTT TGTGATTGGT ATTGCACAGG TCATGCATTT AGAAGATTTT 
AATGAAGGTG CTTCATTTTC AAATTTGACT GCAGGCCCAT ATCCTCTAAT TATTACAATT 
ATCATGCTCA CACTTAATAG TATATTCTAT GTCCTCTTGG CTGTCTATCT TGATCAAGTC 
ATTCCAGGGG AATTTGGCTT ACGGAGATCA TCTTTATATT TTCTGAAGCC TTCATATTGG 
TCAAAGAGCA AAAGAAATTA TGAGGAGTTA TCAGAGGGCA ATGTTAATGG AAATATTAGT 
TTTAGTGAAA TTATTGAGCC AGTTTCTTCA GAATTTGTAG GAAAAGAAGC CATAAGAATT 
AGTGGTATTC AGAAGACATA CAGAAAGAAG GGTGAAAATG TGGAGGCTTT GAGAAATTTG 
TCATTTGACA TATATGAGGG TCAGATTACT GCCTTACTTG GCCACAGTGG AACAGGAAAG 
AGTACATTGA TGAATATTCT TTGTGGACTC TGCCCACCTT CTGATGGGTT TGCATCTATA 
TATGGACACA GAGTCTCAGA AATAGATGAA ATGTTTGAAG CAAGAAAAAT GATTGGCATT 
TGTCCACAGT TAGATATACA CTTTGATGTT TTGACAGTAG AAGAAAATTT ATCAATTTTG 
GCTTCAATCA AAGGGATACC AGCCAACAAT ATAATACAAG AAGTGCAGAA GGTTTTACTA 
GATTTAGACA TGCAGACTAT CAAAGATAAC CAAGCTAAAA AATTAAGTGG TGGTCAAAAA 
AGAAAGCTGT CATTAGGAAT TGCTGTTCTT GGGAACCCAA AGATACTGCT GCTAGATGAA 
CCAACAGCTG GAATGGACCC CTGTTCTCGA CATATTGTAT GGAATCTTTT AAAATACAGA 
AAAGCCAATC GGGTGACAGT GTTCAGTACT CATTTCATGG ATGAAGCTGA CATTCTTGCA 
GATAGGAAAG CTGTGATATC ACAAGGAATG CTGAAATGTG TTGGTTCTTC AATGTTCCTC 
AAAAGTAAAT GGGGGATCGG CTACCGCCTG AGCATGTACA TAGACAAATA TTGTGCCACA 
GAATCTCTTT CTTCACTGGT TAAACAACAT ATACCTGGAG CTACTTTATT ACAACAGAAT 
GACCAACAAC TTGTGTATAG CTTGCCTTTC AAGGACATGG ACAAATTTTC AGGTTTGTTT 
TCTGCCCTAG ACAGTCATTC AAATTTGGGT GTCATTTCTT ATGGTGTTTC CATGACGACT 
TTGGAAGACG TATTTTTAAA GCTAGAAGTT GAAGCAGAAA TTGACCAAGC AGATTATAGT 
GTATTTACTC AGCAGCCACT GGAGGAAGAA ATGGATTCAA AATCTTTTGA TGAAATGGAA 
CAGAGCTTAC TTATTCTTTC TGAAACCAAG GCTGCTCTAG TGAGCACCAT GAGCCTTTGG 
AAACAACAGA TGTATACAAT AGCAAAGTTT CATTTCTTTA CCTTGAAACG TGAAAGTAAA 
TCAGTGAGAT CAGTGTTGCT TCTGCTTTTA ATTTTTTTCA CAGTTCAGAT TTTTATGTTT 
TTGGTTCATC ACTCTTTTAA AAATGCTGTG GTTCCCATCA AACTTGTTCC AGACTTATAT 
TTTCTAAAAC CTGGAGACAA ACCACATAAA TACAAAACAA GTCTGCTTCT TCAAAATTCT 
GCTGACTCAG ATATCAGTGA TCTTATTAGC TTTTTCACAA GCCAGAACAT AATGGTGACG 
ATGATTAATG ACAGTGACTA TGTATCCGTG GCTCCCCATA GTGCGGCTTT AAATGTGATG 
CATTCAGAAA AGGACTATGT TTTTGCAGCT GTTTTCAACA GTACTATGGT TTATTCTTTA 
CCTATATTAG TGAATATCAT TAGTAACTAC TATCTTTATC ATTTAAATGT GACTGAAACC 
ATCCAGATCT GGAGTACCCC ATTCTTTCAA GAAATTACTG ATATAGTTTT TAAAATTGAG 
CTGTATTTTC AAGCAGCTTT GCTTGGAATC ATTGTTACTG CAATGCCACC TTACTTTGCC 
ATGGAAAATG CAGAGAATCA TAAGATCAAA GCTTATACTC AACTTAAACT TTCAGGTCTT 
TTGCCATCTG CATATTGGAT TGGACAAGCT GTTGTTGATA TCCCCTTATT TTTTATCATT 
CTTATTTTGA TGCTAGGAAG CTTATTGGCA TTTCATTATG GATTATATTT TTATACTGTA 
AAGTTCCTTG CTGTGGTTTT TTGCCTTATT GGTTATGTTC CATCAGTTAT TCTGTTCACT 
TATATTGCTT CTTTCACCTT TAAGAAAATT TTAAATACCA AAGAATTTTG GTCATTTATC 
TATTCTGTGG CAGCGTTGGC TTGTATTGCA ATCACTGAAA TAACTTTCTT TATGGGATAC 
ACAATTGCAA CTATTCTTCA TTATGCCTTT TGTATCATCA TTCCAATCTA TCCACTTCTA 
GGTTGCCTGA TTTCTTTCAT AAAGATTTCT TGGAAGAATG TACGAAAAAA TGTGGACACC 
TATAATCCAT GGGATAGGCT TTCAGTAGCT GTTATATCGC CTTACCTGCA GTGTGTACTG 
TGGATTTTCC TCTTACAATA CTATGAGAAA AAATATGGAG GCAGATCAAT AAGAAAAGAT 
CCCTTTTTCA GAAACCTTTC AACGAAGTCT AAAAATAGGA AGCTTCCAGA ACCACCAGAC 
AATGAGGATG AAGATGAAGA TGTCAAAGCT GAAAGACTAA AGGTCAAAGA GCTGATGGGT 
TGCCAGTGTT GTGAGGAGAA ACCATCCATT ATGGTCAGCA ATTTGCATAA AGAATATGAT 
GACAAGAAAG ATTTTCTTCT TTCAAGAAAA GTAAAGAAAG TGGCAACTAA ATACATCTCT 
TTCTGTGTGA AAAAAGGAGA GATCTTAGGA CTATTGGGTC CAAATGGTGC TGGCAAAAGC 
ACAATTATTA ATATTCTGGT TGGTGATATT GAACCAACTT CAGGCCAGGT ATTTTTAGGA 
GATTATTCTT CAGAGACAAG TGAAGATGAT GATTCACTGA AGTGTATGGG TTACTGTCCT 
CAGATAAACC CTTTGTGGCC AGATACTACA TTGCAGGAAC ATTTTGAAAT TTATGGAGCT 
GTCAAAGGAA TGAGTGCAAG TGACATGAAA GAAGTCATAA GTCGAATAAC ACATGCACTT 
GATTTAAAAG AACATCTTCA GAAGACTGTA AAGAAACTAC CTGCAGGAAT CAAACGAAAG 
TTGTGTTTTG CTCTAAGTAT GCTAGGGAAT CCTCAGATTA CTTTGCTAGA TGAACCATCT 
ACAGGTATGG ATCCCAAAGC CAAACAGCAC ATGTGGCGAG CAATTCGAAC TGCATTTAAA 
AACAGAAAGC GGGCTGCTAT TCTGACCACT CACTATATGG AGGAGGCAGA GGCTGTCTGT 
GATCGAGTAG CTATCATGGT GTCTGGGCAG TTAAGATGTA TCGGAACAGT ACAACATCTA 
AAGAGTAAAT TTGGAAAAGG CTACTTTTTG GAAATTAAAT TGAAGGACTG GATAGAAAAC 
CTAGAAGTAG ACCGCCTTCA AAGAGAAATT CAGTATATTT TCCCAAATGC AAGCCGTCAG 
GAAAGTTTTT CTTCTATTTT GGCTTATAAA ATTCCTAAGG AAGATGTTCA GTCCCTTTCA 
CAATCTTTTT TTAAGCTGGA AGAAGCTAAA CATGCTTTTG CCATTGAAGA ATATAGCTTT 
TCTCAAGCAA CATTGGAACA GGTTTTTGTA GAACTCACTA AAGAACAAGA GGAGGAAGAT 
AATAGTTGTG GAACTTTAAA CAGCACACTT TGGTGGGAAC GAACACAAGA AGATAGAGTA 
GTATTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_758424.1
CDS	98..5026
Translation	MSTAIREVGVWRQTRTLLLKNYLIKCRTKKSSVQEILFPLFFLFWLILISMMHPNKKYEEVPNIELNPMDKFTLSNLILGYTPVTNITSSIMQKVSTDHLPDVIITEEYTNEKEMLTSSLSKPSNFVGVVFKDSMSYELRFFPDMIPVSSIYMDSRAGCSKSCEAAQYWSSGFTVLQASIDAAIIQLKTNVSLWKELESTKAVIMGETAVVEIDTFPRGVILIYLVIAFSPFGYFLAIHIVAEKEKKIKEFLKIMGLHDTAFWLSWVLLYTSLIFLMSLLMAVIATASLLFPQSSSIVIFLLFFLYGLSSVFFALMLTPLFKKSKHVGIVEFFVTVAFGFIGLMIILIESFPKSLVWLFSPFCHCTFVIGIAQVMHLEDFNEGASFSNLTAGPYPLIITIIMLTLNSIFYVLLAVYLDQVIPGEFGLRRSSLYFLKPSYWSKSKRNYEELSEGNVNGNISFSEIIEPVSSEFVGKEAIRISGIQKTYRKKGENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARKMIGICPQLDIHFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQTIKDNQAKKLSGGQKRKLSLGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVGSSMFLKSKWGIGYRLSMYIDKYCATESLSSLVKQHIPGATLLQQNDQQLVYSLPFKDMDKFSGLFSALDSHSNLGVISYGVSMTTLEDVFLKLEVEAEIDQADYSVFTQQPLEEEMDSKSFDEMEQSLLILSETKAALVSTMSLWKQQMYTIAKFHFFTLKRESKSVRSVLLLLLIFFTVQIFMFLVHHSFKNAVVPIKLVPDLYFLKPGDKPHKYKTSLLLQNSADSDISDLISFFTSQNIMVTMINDSDYVSVAPHSAALNVMHSEKDYVFAAVFNSTMVYSLPILVNIISNYYLYHLNVTETIQIWSTPFFQEITDIVFKIELYFQAALLGIIVTAMPPYFAMENAENHKIKAYTQLKLSGLLPSAYWIGQAVVDIPLFFIILILMLGSLLAFHYGLYFYTVKFLAVVFCLIGYVPSVILFTYIASFTFKKILNTKEFWSFIYSVAALACIAITEITFFMGYTIATILHYAFCIIIPIYPLLGCLISFIKISWKNVRKNVDTYNPWDRLSVAVISPYLQCVLWIFLLQYYEKKYGGRSIRKDPFFRNLSTKSKNRKLPEPPDNEDEDEDVKAERLKVKELMGCQCCEEKPSIMVSNLHKEYDDKKDFLLSRKVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDDSLKCMGYCPQINPLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSKFGKGYFLEIKLKDWIENLEVDRLQREIQYIFPNASRQESFSSILAYKIPKEDVQSLSQSFFKLEEAKHAFAIEEYSFSQATLEQVFVELTKEQEEEDNSCGTLNSTLWWERTQEDRVVF

Target ORF information:

RefSeq Version	NM_172232.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ATP binding cassette subfamily A member 5 (ABCA5), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_172232.4

ORF Insert Sequence:

ATGTCCACTG CAATTAGGGA GGTAGGAGTT TGGAGACAGA CCAGAACACT TCTACTGAAG 
AATTACTTAA TTAAATGCAG AACCAAAAAG AGTAGTGTTC AGGAAATTCT TTTTCCACTA 
TTTTTTTTAT TTTGGTTAAT ATTAATTAGC ATGATGCATC CAAATAAGAA ATATGAAGAA 
GTGCCTAATA TAGAACTCAA TCCTATGGAC AAGTTTACTC TTTCTAATCT AATTCTTGGA 
TATACTCCAG TGACTAATAT TACAAGCAGC ATCATGCAGA AAGTGTCTAC TGATCATCTA 
CCTGATGTCA TAATTACTGA AGAATATACA AATGAAAAAG AAATGTTAAC ATCCAGTCTC 
TCTAAGCCGA GCAACTTTGT AGGTGTGGTT TTCAAAGACT CCATGTCCTA TGAACTTCGT 
TTTTTTCCTG ATATGATTCC AGTATCTTCT ATTTATATGG ATTCAAGAGC TGGCTGTTCA 
AAATCATGTG AGGCTGCTCA GTACTGGTCC TCAGGTTTCA CAGTTTTACA AGCATCCATA 
GATGCTGCCA TTATACAGTT GAAGACCAAT GTTTCTCTTT GGAAGGAGCT GGAGTCAACT 
AAAGCTGTTA TTATGGGAGA AACTGCTGTT GTAGAAATAG ATACCTTTCC CCGAGGAGTA 
ATTTTAATAT ACCTAGTTAT AGCATTTTCA CCTTTTGGAT ACTTTTTGGC AATTCATATC 
GTAGCAGAAA AAGAAAAAAA AATAAAAGAA TTTTTAAAGA TAATGGGACT TCATGATACT 
GCCTTTTGGC TTTCCTGGGT TCTTCTATAT ACAAGTTTAA TTTTTCTTAT GTCCCTTCTT 
ATGGCAGTCA TTGCGACAGC TTCTTTGTTA TTTCCTCAAA GTAGCAGCAT TGTGATATTT 
CTGCTTTTTT TCCTTTATGG ATTATCATCT GTATTTTTTG CTTTAATGCT GACACCTCTT 
TTTAAAAAAT CAAAACATGT GGGAATAGTT GAATTTTTTG TTACTGTGGC TTTTGGATTT 
ATTGGCCTTA TGATAATCCT CATAGAAAGT TTTCCCAAAT CGTTAGTGTG GCTTTTCAGT 
CCTTTCTGTC ACTGTACTTT TGTGATTGGT ATTGCACAGG TCATGCATTT AGAAGATTTT 
AATGAAGGTG CTTCATTTTC AAATTTGACT GCAGGCCCAT ATCCTCTAAT TATTACAATT 
ATCATGCTCA CACTTAATAG TATATTCTAT GTCCTCTTGG CTGTCTATCT TGATCAAGTC 
ATTCCAGGGG AATTTGGCTT ACGGAGATCA TCTTTATATT TTCTGAAGCC TTCATATTGG 
TCAAAGAGCA AAAGAAATTA TGAGGAGTTA TCAGAGGGCA ATGTTAATGG AAATATTAGT 
TTTAGTGAAA TTATTGAGCC AGTTTCTTCA GAATTTGTAG GAAAAGAAGC CATAAGAATT 
AGTGGTATTC AGAAGACATA CAGAAAGAAG GGTGAAAATG TGGAGGCTTT GAGAAATTTG 
TCATTTGACA TATATGAGGG TCAGATTACT GCCTTACTTG GCCACAGTGG AACAGGAAAG 
AGTACATTGA TGAATATTCT TTGTGGACTC TGCCCACCTT CTGATGGGTT TGCATCTATA 
TATGGACACA GAGTCTCAGA AATAGATGAA ATGTTTGAAG CAAGAAAAAT GATTGGCATT 
TGTCCACAGT TAGATATACA CTTTGATGTT TTGACAGTAG AAGAAAATTT ATCAATTTTG 
GCTTCAATCA AAGGGATACC AGCCAACAAT ATAATACAAG AAGTGCAGAA GGTTTTACTA 
GATTTAGACA TGCAGACTAT CAAAGATAAC CAAGCTAAAA AATTAAGTGG TGGTCAAAAA 
AGAAAGCTGT CATTAGGAAT TGCTGTTCTT GGGAACCCAA AGATACTGCT GCTAGATGAA 
CCAACAGCTG GAATGGACCC CTGTTCTCGA CATATTGTAT GGAATCTTTT AAAATACAGA 
AAAGCCAATC GGGTGACAGT GTTCAGTACT CATTTCATGG ATGAAGCTGA CATTCTTGCA 
GATAGGAAAG CTGTGATATC ACAAGGAATG CTGAAATGTG TTGGTTCTTC AATGTTCCTC 
AAAAGTAAAT GGGGGATCGG CTACCGCCTG AGCATGTACA TAGACAAATA TTGTGCCACA 
GAATCTCTTT CTTCACTGGT TAAACAACAT ATACCTGGAG CTACTTTATT ACAACAGAAT 
GACCAACAAC TTGTGTATAG CTTGCCTTTC AAGGACATGG ACAAATTTTC AGGTTTGTTT 
TCTGCCCTAG ACAGTCATTC AAATTTGGGT GTCATTTCTT ATGGTGTTTC CATGACGACT 
TTGGAAGACG TATTTTTAAA GCTAGAAGTT GAAGCAGAAA TTGACCAAGC AGATTATAGT 
GTATTTACTC AGCAGCCACT GGAGGAAGAA ATGGATTCAA AATCTTTTGA TGAAATGGAA 
CAGAGCTTAC TTATTCTTTC TGAAACCAAG GCTGCTCTAG TGAGCACCAT GAGCCTTTGG 
AAACAACAGA TGTATACAAT AGCAAAGTTT CATTTCTTTA CCTTGAAACG TGAAAGTAAA 
TCAGTGAGAT CAGTGTTGCT TCTGCTTTTA ATTTTTTTCA CAGTTCAGAT TTTTATGTTT 
TTGGTTCATC ACTCTTTTAA AAATGCTGTG GTTCCCATCA AACTTGTTCC AGACTTATAT 
TTTCTAAAAC CTGGAGACAA ACCACATAAA TACAAAACAA GTCTGCTTCT TCAAAATTCT 
GCTGACTCAG ATATCAGTGA TCTTATTAGC TTTTTCACAA GCCAGAACAT AATGGTGACG 
ATGATTAATG ACAGTGACTA TGTATCCGTG GCTCCCCATA GTGCGGCTTT AAATGTGATG 
CATTCAGAAA AGGACTATGT TTTTGCAGCT GTTTTCAACA GTACTATGGT TTATTCTTTA 
CCTATATTAG TGAATATCAT TAGTAACTAC TATCTTTATC ATTTAAATGT GACTGAAACC 
ATCCAGATCT GGAGTACCCC ATTCTTTCAA GAAATTACTG ATATAGTTTT TAAAATTGAG 
CTGTATTTTC AAGCAGCTTT GCTTGGAATC ATTGTTACTG CAATGCCACC TTACTTTGCC 
ATGGAAAATG CAGAGAATCA TAAGATCAAA GCTTATACTC AACTTAAACT TTCAGGTCTT 
TTGCCATCTG CATATTGGAT TGGACAAGCT GTTGTTGATA TCCCCTTATT TTTTATCATT 
CTTATTTTGA TGCTAGGAAG CTTATTGGCA TTTCATTATG GATTATATTT TTATACTGTA 
AAGTTCCTTG CTGTGGTTTT TTGCCTTATT GGTTATGTTC CATCAGTTAT TCTGTTCACT 
TATATTGCTT CTTTCACCTT TAAGAAAATT TTAAATACCA AAGAATTTTG GTCATTTATC 
TATTCTGTGG CAGCGTTGGC TTGTATTGCA ATCACTGAAA TAACTTTCTT TATGGGATAC 
ACAATTGCAA CTATTCTTCA TTATGCCTTT TGTATCATCA TTCCAATCTA TCCACTTCTA 
GGTTGCCTGA TTTCTTTCAT AAAGATTTCT TGGAAGAATG TACGAAAAAA TGTGGACACC 
TATAATCCAT GGGATAGGCT TTCAGTAGCT GTTATATCGC CTTACCTGCA GTGTGTACTG 
TGGATTTTCC TCTTACAATA CTATGAGAAA AAATATGGAG GCAGATCAAT AAGAAAAGAT 
CCCTTTTTCA GAAACCTTTC AACGAAGTCT AAAAATAGGA AGCTTCCAGA ACCACCAGAC 
AATGAGGATG AAGATGAAGA TGTCAAAGCT GAAAGACTAA AGGTCAAAGA GCTGATGGGT 
TGCCAGTGTT GTGAGGAGAA ACCATCCATT ATGGTCAGCA ATTTGCATAA AGAATATGAT 
GACAAGAAAG ATTTTCTTCT TTCAAGAAAA GTAAAGAAAG TGGCAACTAA ATACATCTCT 
TTCTGTGTGA AAAAAGGAGA GATCTTAGGA CTATTGGGTC CAAATGGTGC TGGCAAAAGC 
ACAATTATTA ATATTCTGGT TGGTGATATT GAACCAACTT CAGGCCAGGT ATTTTTAGGA 
GATTATTCTT CAGAGACAAG TGAAGATGAT GATTCACTGA AGTGTATGGG TTACTGTCCT 
CAGATAAACC CTTTGTGGCC AGATACTACA TTGCAGGAAC ATTTTGAAAT TTATGGAGCT 
GTCAAAGGAA TGAGTGCAAG TGACATGAAA GAAGTCATAA GTCGAATAAC ACATGCACTT 
GATTTAAAAG AACATCTTCA GAAGACTGTA AAGAAACTAC CTGCAGGAAT CAAACGAAAG 
TTGTGTTTTG CTCTAAGTAT GCTAGGGAAT CCTCAGATTA CTTTGCTAGA TGAACCATCT 
ACAGGTATGG ATCCCAAAGC CAAACAGCAC ATGTGGCGAG CAATTCGAAC TGCATTTAAA 
AACAGAAAGC GGGCTGCTAT TCTGACCACT CACTATATGG AGGAGGCAGA GGCTGTCTGT 
GATCGAGTAG CTATCATGGT GTCTGGGCAG TTAAGATGTA TCGGAACAGT ACAACATCTA 
AAGAGTAAAT TTGGAAAAGG CTACTTTTTG GAAATTAAAT TGAAGGACTG GATAGAAAAC 
CTAGAAGTAG ACCGCCTTCA AAGAGAAATT CAGTATATTT TCCCAAATGC AAGCCGTCAG 
GAAAGTTTTT CTTCTATTTT GGCTTATAAA ATTCCTAAGG AAGATGTTCA GTCCCTTTCA 
CAATCTTTTT TTAAGCTGGA AGAAGCTAAA CATGCTTTTG CCATTGAAGA ATATAGCTTT 
TCTCAAGCAA CATTGGAACA GGTTTTTGTA GAACTCACTA AAGAACAAGA GGAGGAAGAT 
AATAGTTGTG GAACTTTAAA CAGCACACTT TGGTGGGAAC GAACACAAGA AGATAGAGTA 
GTATTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ABCA5 regulates amyloid-? peptide production and is associated with Alzheimer's disease neuropathology.
Journal of Alzheimer's disease : JAD43(3)857-69(2015)
Fu Y,Hsiao JH,Paxinos G,Halliday GM,Kim WS

Mutations in the cholesterol transporter gene ABCA5 are associated with excessive hair overgrowth.
PLoS genetics10(5)e1004333(2014)
DeStefano GM,Kurban M,Anyane-Yeboa K,Dall'Armi C,Di Paolo G,Feenstra H,Silverberg N,Rohena L,L?pez-Cepeda LD,Jobanputra V,Fantauzzo KA,Kiuru M,Tadin-Strapps M,Sobrino A,Vitebsky A,Warburton D,Levy B,Salas-Alanis JC,Christiano AM

Identification of CBX3 and ABCA5 as putative biomarkers for tumor stem cells in osteosarcoma.
PloS one7(8)e41401(2012)
Saini V,Hose CD,Monks A,Nagashima K,Han B,Newton DL,Millione A,Shah J,Hollingshead MG,Hite KM,Burkett MW,Delosh RM,Silvers TE,Scudiero DA,Shoemaker RH

Changes in sphingomyelin level affect alpha-synuclein and ABCA5 expression.
Journal of Parkinson's disease2(1)41-6(2012)
Kim WS,Halliday GM

ATP-binding cassette transporter ABCB5 gene is expressed with variability in malignant melanoma.
Actas dermo-sifiliograficas101(4)341-8(2010 May)
V?squez-Moctezuma I,Meraz-R?os MA,Villanueva-L?pez CG,Maga?a M,Mart?nez-Macias R,S?nchez-Gonz?lez DJ,Garc?a-Sierra F,Herrera-Gonz?lez NE

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ABCA5 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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